Methylation biomarkers and methods of use

ABSTRACT

Disclosed are methods and compositions of assessing one or more statuses of a subject. Also disclosed are methods and compositions of identifying status biomarkers associated with a status of a subject. Also disclosed are sets of one or more status biomarkers. Also disclosed are methods and compositions of producing status biomarker capture probes.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims benefit of U.S. Provisional Application No.61/234,367, filed Aug. 17, 2009. Application No. 61/234,367, filed Aug.17, 2009, is hereby incorporated herein by reference in its entirety.

STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH

This invention was made with government support under grant No.1R21CA116079 from the National Institutes of Health (NIH). Thegovernment has certain rights in the invention.

BACKGROUND

The DNA of most tumors has a reduced content of methylated cytosineresidues. This so-called global “hypomethylation” affects primarily DNAsequences that belong to interspersed DNA repeats. In normal humantissues, DNA repeats are predominantly methylated, consistent with therequirement to maintain genomic stability by transcriptional silencingof retroelements whose potential deleterious functions include DNAmobilization as well as the facilitation of recombination events insomatic cells.

BRIEF SUMMARY

Disclosed are methods and compositions of assessing one or more statusesof a subject. Also disclosed are methods and compositions of identifyingstatus biomarkers associated with a status of a subject. Also disclosedare sets of one or more status biomarkers. Also disclosed are methodsand compositions of producing status biomarker capture probes.

In some forms of the methods and compositions of assessing one or morestatuses of a subject, the method can comprise, for example, determiningthe methylation state of one or more status biomarkers in the subject,and comparing one or more of the determined methylation states to one ormore reference methylation states, wherein a difference, lack of adifference, or both in one or more of the determined methylation statesand one or more of the reference methylation states indicates one ormore statuses of the subject.

In some forms of the methods and compositions of identifying statusbiomarkers associated with a status of a subject, the method cancomprise, for example, determining the methylation state of one or morestatus biomarkers in one or more DNA samples, wherein the DNA samplesare from sources that are relevant to one or more specific statuses, andcomparing one or more of the determined methylation states to one ormore reference methylation states, wherein a difference in one or moreof the determined methylation states and one or more of the referencemethylation states indicates that the status biomarkers for which thedifference in the methylation states is found is a status biomarkerassociated with one or more of the specific statuses.

In some forms, the methylation state can be determined by, for example,treating a DNA sample of the subject to differentiate methylated andunmethylated nucleotides, and detecting the level of methylated forms ofthe one or more status biomarkers in the treated DNA, detecting thelevel of unmethylated forms of the one or more status biomarkers in thetreated DNA, or both, wherein the level of methylated forms of thestatus biomarkers, the level of unmethylated forms of the statusbiomarkers, or both indicates the methylation state of the statusbiomarkers.

In some forms, treating the DNA sample can be accomplished by, forexample, incubating the DNA sample with one or more restrictionendonucleases and amplifying the incubated DNA, wherein the restrictionendonucleases are methylation-sensitive restriction endonucleases,wherein the level of the status biomarkers in the amplified DNA is lowerwhen the status biomarkers have reduced methylation and the level of thestatus biomarkers in the amplified DNA is higher when the statusbiomarkers have increased methylation, wherein the level of the statusbiomarkers comprise the level of methylated forms of the one or morestatus biomarkers in the treated DNA, the level of unmethylated forms ofthe one or more status biomarkers in the treated DNA, or both.

In some forms, the restriction endonucleases can further comprise atleast one methylation-dependent restriction endonuclease. In some forms,the restriction endonucleases can further comprise at least onemethylation-independent restriction endonuclease. In some forms, therestriction endonucleases can comprise AciI and HhaI. In some forms, therestriction endonucleases can comprise McrBC. In some forms, incubatingthe DNA sample with one or more endonucleases can be accomplished by,for example, incubating different aliquots of the DNA sample withdifferent restriction endonucleases. In some forms, amplifying theincubated DNA can be accomplished by, for example, multiple displacementamplification.

In some forms, treating the DNA sample can be accomplished by, forexample, processing the DNA sample with sodium bisulfite.

In some forms, treating the DNA sample can be accomplished by, forexample, fragmenting the DNA and separating methylated DNA fromunmethylated DNA. In some forms, the DNA can be fragmented by, forexample, nebularization, cleavage with a restriction endonuclease,sonication, or a combination. In some forms, methylated DNA can beseparated from unmethylated DNA by, for example, binding methylated DNAwith a specific binding molecule specific for methyl groups andseparating the bound from the unbound DNA. In some forms, the specificbinding molecule can comprise, for example, an antibody specific for5-methyl cytosine, methyl-biding protein MBD1, methyl-biding proteinMECP2, or a combination.

In some forms, treating the DNA sample can be accomplished by, forexample, capturing status biomarker DNA fragments and sequencing thecaptured status biomarker DNA fragments, wherein the sequencingdistinguishes cytosine from methylcytosine, wherein the level ofmethylcytosine indicates level of methylated forms of the statusbiomarkers. In some forms, the status biomarker DNA fragments can becaptured by, for example, binding DNA fragments in the DNA sample tostatus biomarker probes attached to a support. In some forms, one ormore of the status biomarker probes can specifically hybridize to one ormore repetitive DNA sequences, wherein the one or more of the statusbiomarker probes comprises degenerate sequence representing a consensussequence for a family of repetitive DNA sequences. In some forms, eachof the status biomarker probes can specifically hybridize to one or morerepetitive DNA sequences, wherein each of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, the family ofrepetitive DNA sequences can be a family of repetitive DNA sequenceslisted in, for example, Table 1. In some forms, the one or more of thestatus biomarker probes can comprise different degenerate sequences eachrepresenting a consensus sequence for a different one of the families ofrepetitive DNA sequences listed in, for example, Table 1. In some forms,the one or more of the status biomarker probes can comprise at least 20different degenerate sequences each representing a different consensussequence for a different one of the families of repetitive DNA sequenceslisted in, for example, Table 1. In some forms, the support cancomprise, for example, gel, a bead, a magnetic bead, a plate, a slide, asurface, or a microparticle. In some forms, DNA not captured can beseparated from the captured status biomarker DNA fragments. In someforms, the sequencing can be a form of SMRT sequencing.

In some forms, the method can further comprise, after capturing statusbiomarker DNA fragments and prior to sequencing the captured statusbiomarker DNA fragments, releasing the captured status biomarker DNAfragments and recapturing the released status biomarker DNA fragments.In some forms, the status biomarker DNA fragments can be recaptured bybinding DNA fragments in the DNA sample to secondary status biomarkerprobes attached to a support. In some forms, one or more of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein the one or more of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, each of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein each of the status biomarker probes comprisesdegenerate sequence representing a consensus sequence for a family ofrepetitive DNA sequences. In some forms, the family of repetitive DNAsequences can be a family of repetitive DNA sequences listed in, forexample, Table 16 and Table 17. In some forms, the family of repetitiveDNA sequences can be a family of repetitive DNA sequences listed inTable 16 or 17. For example, the family of repetitive DNA sequences canbe the AluY, AluSx, AluSp, AluSg, or AluSc family of repetitive DNAsequences. In some forms, the one or more of the status biomarker probescan comprise different degenerate sequences each representing aconsensus sequence for a different one of the families of repetitive DNAsequences listed in, for example, Table 16 and Table 17. In some forms,the one or more of the status biomarker probes can comprise differentdegenerate sequences each representing a consensus sequence for adifferent one of the families of repetitive DNA sequences listed inTable 16 or 17, such as AluY, AluSx, AluSp, AluSg, or AluSc. In someforms, the support can comprise, for example, gel, a bead, a magneticbead, a plate, a slide, a surface, or a microparticle. In some forms,DNA not recaptured can be separated from the recaptured status biomarkerDNA fragments.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, an array of probes specific for thestatus biomarkers. In some forms, the array of probes can be, forexample, a microarray.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, amplifying the processed DNA anddetermining the ratio of cytosine to thymidine in the amplified DNA andconverting the ratio to the level of methylated forms of the statusbiomarkers. In some forms, the processed DNA can be amplified via, forexample, PCR amplification of the status biomarkers using primersspecific for the status biomarkers.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, PCR amplification of the statusbiomarkers using primers specific for the status biomarkers. In someforms, the PCR amplification can be quantitative PCR. In some forms, thePCR amplification can be nanoliter-microarray quantitative PCR.

In some forms, the level of the status biomarkers can be grouped into aplurality of status biomarker families, wherein the level of the statusbiomarkers in one or more of the families is analyzed, wherein theanalyzed level of the status biomarkers in the one or more of thefamilies indicates the methylation state of the status biomarkers in thefamily. In some forms, the analyzed level of the status biomarkers inone or more of the families can be the average of the levels of theindividual status biomarkers in the family. In some forms, one or moreof the status biomarker families each independently can consist of, forexample, a single class of repetitive DNA element, a single subclass ofrepetitive DNA element, a single family of repetitive DNA element, asingle subfamily of repetitive DNA element, or a combination. In someforms, the analyzed level of the status biomarkers in one or more of thefamilies can be normalized to one or more of the reference methylationstates. In some forms, the level of one or more of the status biomarkerscan be normalized to one or more of the reference methylation states. Insome forms, the level of one or more of the status biomarker familiescan be normalized to one or more of the reference methylation states. Insome forms, the status biomarkers can be grouped according to one ormore repetitive DNA sequences that the status biomarkers comprise,wherein each biomarker in each status biomarker family comprises one ormore repetitive DNA sequences that belong to a single family ofrepetitive DNA sequences listed in, for example, Table 1.

In some forms, one or more of the one or more reference methylationstates can be a normal methylation state. In some forms, the normalmethylation state can be, for example, the methylation state of ahealthy subject, the average of the methylation states of healthysubjects, or the average of the methylation states of a population ofsubjects. In some forms, one or more of the one or more referencemethylation states can be, for example, the methylation state of thesame subject at a different time, the methylation state of the samesubject at an earlier time, the methylation state of the same subject ata later time, or the methylation state of one or more normal cells,tissues, organs, or a combination of the same subject. In some forms,one or more of the one or more reference methylation states can be themethylation state from non-tumor adjacent tissue. In some forms, one ormore of the one or more reference methylation states can be a normalmethylation state of a status biomarker family.

In some forms, the method can further comprise determining the geneticstate of one or more status biomarkers by, for example, comparing one ormore of the determined genetic states to one or more reference geneticstates, wherein a difference, lack of a difference, or both in one ormore of the determined genetic states and one or more of the referencegenetic states indicates one or more statuses of the subject. In someforms, determining the genetic state of one or more status biomarkerscan be determined in one or more of the DNA samples.

In some forms, the source of one or more of the DNA samples can be oneor more tissues of the subject, organs of the subject, or both. In someforms, the source of one or more of the DNA samples can be a tissue ororgan of the subject. In some forms, the source of one or more of theDNA samples can be one or more cells of the subject. In some forms, thesource of one or more of the DNA samples can be one or more cells,tissue, skin, lung, head, neck, prostate, breast, ovary, brain, liver,stomach, intestine, kidney, testicle, cervix, uterus, spleen, bone,throat, esophagus, muscle, bodily fluids, blood, urine, semen, lymphaticfluid, cerebrospinal fluid, amniotic fluid, biological samples, tissueculture cells, buccal swabs, mouthwash, stool, tissues slices, biopsyaspiration, or a combination.

In some forms, the subject can be assessed for the status of wellness,level of health, risk to wellness, risk to level of health, or acombination. In some forms, the subject can be assessed for the statusof the genome. In some forms, the subject can be assessed for the statusof aging, risk of aging, or both. In some forms, the subject can beassessed for the status of cancer, risk of cancer, or both. In someforms, the subject can be assessed for the status of stress response. Insome forms, the subject can be assessed for the status of diabetes, riskof diabetes, or both. In some forms, the subject can be assessed for thestatus of heart disease, risk of heart disease, or both. In some forms,the subject can be assessed for the status of genomic instability. Insome forms, the subject can be assessed for the status of tumor burden.In some forms, the subject can be assessed for the status of response totreatment.

In some forms, the subject can be assessed for a change in one or morestatuses. In some forms, the change in one or more of the one or morestatuses can be assessed compared to an earlier assessment. In someforms, the earlier assessment can have been made at, for example, anearlier time, prior to diagnosis of a disease or condition, prior to atreatment, following diagnosis of a disease or condition, followingtreatment, or a combination. In some forms, the change in one or more ofthe one or more statuses can be assessed following the passage of time,prior to diagnosis of a disease or condition, prior to a treatment,following diagnosis of a disease or condition, following treatment, or acombination. In some forms, assessing the subject can comprise assessingone or more tissues of the subject, organs of the subject, or both. Insome forms, assessing the subject can comprise assessing a tissue ororgan of the subject. In some forms, assessing the subject can compriseassessing one or more cells of the subject.

In some forms, the status biomarkers can comprise nucleic acid sequencesin the genome of the species to which the subject belongs. In some formsof the sets of one or more status biomarkers the status biomarkers cancomprise, for example, nucleic acid sequences in a genome. In someforms, the nucleic acid sequences can be in proximity to CpG islands orislets, wherein the CpG islands or islets comprise nucleic acid regionsgreater than 100 nucleotides in length that contain a minimum of 5 CpGresidues and have a ratio of CG content to GC content greater than 0.3.In some forms, the CpG islands or islets can comprise nucleic acidregions greater than 200 nucleotides in length. In some forms, the CpGislands or islets can comprise nucleic acid regions greater than 300nucleotides in length. In some forms, the nucleic acid regions can havea ratio of CG content to GC content greater than 0.4. In some forms, thenucleic acid regions can have a ratio of CG content to GC contentgreater than 0.5. In some forms, the status biomarkers can be inproximity to CpG islands or islets when they are within 1200 bases of aCpG island or islet.

In some forms, one or more of the status biomarkers can overlap with allor part of a CpG island or islet. In some forms, the one or more of thestatus biomarkers can comprise a probe binding site, wherein the probebinding site of the one or more of the status biomarkers is specific fora probe. In some forms, one or more of the probes can be specific for arepetitive DNA sequence locus, wherein the repetitive DNA sequence locuscomprises one or more repetitive DNA sequences, wherein independentlyfor each of the one or more of the probes one or more of the repetitiveDNA sequences belongs to a family of repetitive DNA sequences listed in,for example, Table 1. In some forms, each probe can be specific for arepetitive DNA sequence locus, wherein independently for each probe oneor more of the repetitive DNA sequences belongs to a family ofrepetitive DNA sequences listed in, for example, Table 1. In some forms,one or more of the probes can be specific for a repetitive DNA sequencelocus, wherein the repetitive DNA sequence locus comprises one or morerepetitive DNA sequences, wherein for one or more of the probes one ormore of the repetitive DNA sequences is an interspersed repeat element.In some forms, each probe can be specific for a repetitive DNA sequencelocus, wherein for each probe one or more of the repetitive DNAsequences is an interspersed repeat element.

In some forms, one or more of the status biomarkers can comprise a PCRamplicon. In some forms, the PCR amplicon of each of the one or more ofthe status biomarkers can be defined by a first primer specific for asingle one of the status biomarkers and a second primer. In some forms,the PCR amplicon of each of the one or more of the status biomarkers canbe defined by the same first primer specific for a first type ofrepetitive DNA sequence and a second primer, wherein the second primeris specific for a second type of repetitive DNA sequence, wherein thesecond primer is the same for some and different for some of the one ormore of the status biomarkers. In some forms, the first primer can bespecific for one of the families of repetitive DNA sequences listed inTable 16 or 17, wherein independently for each of the one or more of thestatus biomarkers the second primer is specific for a family ofrepetitive DNA sequences listed in, for example, Table 1.

In some forms, one or more of the status biomarkers can comprise one ormore repetitive DNA sequences, wherein independently for each of the oneor more of the status biomarkers that comprise repetitive DNA sequencesone or more of the repetitive DNA sequences belongs to a family ofrepetitive DNA sequences listed in, for example, Table 1. In some forms,each status biomarker can comprise a repetitive DNA sequence, whereinindependently for each of the status biomarkers the repetitive DNAsequence belongs to a family of repetitive DNA sequences listed in, forexample, Table 1. In some forms, one or more of the status biomarkerscan comprise one or more repetitive DNA sequences, wherein for one ormore of the status biomarkers that comprise repetitive DNA sequences oneor more of the repetitive DNA sequences is an interspersed repeatelement. In some forms, each status biomarker can comprise a repetitiveDNA sequence, wherein for each status biomarker the repetitive DNAsequence is an interspersed repeat element.

In some forms, the methylation state of more than 100 biomarkers isdetermined. In some forms, the methylation state of more than 1000biomarkers can be determined. In some forms, the methylation state ofmore than 10,000 biomarkers can be determined. In some forms, themethylation state of more than 100,000 biomarkers can be determined. Insome forms, the methylation state of more than 200,000 biomarkers can bedetermined. In some forms, the status biomarkers can comprise a set ofstatus biomarkers. In some forms, the set can comprise more than 100status biomarkers. In some forms, the set can comprise more than 1000status biomarkers. In some forms, the set can comprise more than 10,000status biomarkers. In some forms, the set can comprise more than 100,000status biomarkers. In some forms, the set can comprise more than 200,000status biomarkers.

In some forms, a plurality of the biomarkers can independently belong toone or more status biomarker families, wherein each biomarker in eachstatus biomarker family comprises one or more repetitive DNA sequencesthat belong to a single family of repetitive DNA sequences listed in,for example, Table 1. In some forms, a plurality of biomarkers canindependently belong to two or more status biomarker families. In someforms, a plurality of biomarkers can independently belong to three ormore status biomarker families. In some forms, a plurality of biomarkerscan independently belong to four or more status biomarker families. Insome forms, a plurality of biomarkers can independently belong to fiveor more status biomarker families. In some forms, a plurality ofbiomarkers can independently belong to ten or more status biomarkerfamilies. In some forms, a plurality of biomarkers can independentlybelong to twenty or more status biomarker families.

In some forms, 100 or more biomarkers can belong to one or more of thestatus biomarker families. In some forms, 100 or more biomarkers canbelong to each of the status biomarker families. In some forms, 200 ormore biomarkers can belong to one or more of the status biomarkerfamilies. In some forms, 200 or more biomarkers can belong to each ofthe status biomarker families. In some forms, 300 or more biomarkers canbelong to one or more of the status biomarker families. In some forms,300 or more biomarkers can belong to each of the status biomarkerfamilies. In some forms, 400 or more biomarkers can belong to one ormore of the status biomarker families. In some forms, the 400 or morebiomarkers can belong to each of the status biomarker families.

In some forms, the status biomarkers can comprise a set of statusbiomarkers. In some forms, the members of the set of status biomarkerscan be status biomarkers that indicate the status of one or morespecific statuses. In some forms, the one or more specific statuses cancomprise, for example, wellness, level of health, risk to wellness, riskto level of health, status of the genome, genomic instability, aging,risk of aging, cancer, risk of cancer, head and neck cancer, risk ofhead and neck cancer, breast cancer, risk of breast cancer, lung cancer,risk of lung cancer, prostate cancer, risk of prostate cancer, coloncancer, risk of colon cancer, esophageal cancer, risk of esophagealcancer, ovarian cancer, risk of ovarian cancer, liver cancer, risk ofliver cancer, pancreatic cancer, risk of pancreatic cancer, skin cancer,risk of skin cancer, melanoma, risk of melanoma, lymphoma, risk oflymphoma, leukemia, risk of leukemia, cervical cancer, risk of cervicalcancer, cervical dysplasia, risk of cervical dysplasia, cervicalintraepithelial neoplasia, risk of cervical intraepithelial neoplasia,tumor burden, stress response, diabetes, risk of diabetes, heartdisease, risk of heart disease, and/or response to treatment.

In some forms, the one or more specific statuses can comprise thepresence of a disease or condition. In some forms, the one or morespecific statuses can comprise, for example, a lack of wellness, lowlevel of health, risk to wellness, risk to level of health, poor statusof the genome, genomic instability, aging, risk of aging, cancer, riskof cancer, head and neck cancer, risk of head and neck cancer, breastcancer, risk of breast cancer, lung cancer, risk of lung cancer,prostate cancer, risk of prostate cancer, colon cancer, risk of coloncancer, esophageal cancer, risk of esophageal cancer, ovarian cancer,risk of ovarian cancer, liver cancer, risk of liver cancer, pancreaticcancer, risk of pancreatic cancer, skin cancer, risk of skin cancer,melanoma, risk of melanoma, lymphoma, risk of lymphoma, leukemia, riskof leukemia, cervical cancer, risk of cervical cancer, cervicaldysplasia, risk of cervical dysplasia, cervical intraepithelialneoplasia, risk of cervical intraepithelial neoplasia, tumor burden,stress response, diabetes, risk of diabetes, heart disease, and/or riskof heart disease.

In some forms of the methods and compositions of producing statusbiomarker capture probes, the method can comprise, for example,selecting a subset of repetitive DNA sequence loci from a set ofrepetitive DNA sequence loci, generating a set of status biomarkercapture probe sequences, and synthesizing one or more status biomarkercapture probes. In some forms, the repetitive DNA sequence loci in theset of repetitive DNA sequence loci can belong to a single one of thefamilies of repetitive DNA sequence listed in, for example, Table 1,wherein the subset of repetitive DNA sequence loci can be selected byidentifying those repetitive DNA sequence loci that comprise arepetitive DNA sequence belonging to one of the families of repetitiveDNA sequences listed in, for example, Table 16 and Table 17.

In some forms, each status biomarker capture probe sequence in the setcan have a length of 50 bases or more, wherein each status biomarkercapture probe represented in the set of status biomarker capture probesequences can hybridize to at least 5% of the repetitive DNA sequenceloci in the selected subset of repetitive DNA sequence loci. In someforms, each status biomarker capture probe can have the sequence of oneof the status biomarker capture probe sequences.

In some forms, the repetitive DNA sequence loci in the set of repetitiveDNA sequence loci can belong to a single one of the families ofrepetitive DNA sequence LTR54B, MER11B, MER34B, LTR56, THE1B, HERV9,LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D, HERVK11, LTR10B, HERVK22,MER6, MER66C, MLT1G1, MER4D, and MLTD2. In some forms, the repetitiveDNA sequence in the subset of repetitive DNA sequence loci can belong toone of the families of repetitive DNA sequences listed in Table 16 or17, such as AluY, AluSx, AluSp, AluSg, AluSc, LTR9, or LTR9B.

In some forms, the method can further comprise selecting one or moreadditional subsets of repetitive DNA sequence loci each from a differentadditional set of repetitive DNA sequence loci, generating one or moreadditional sets of status biomarker capture probe sequences each basedon one of the one or more additional subsets, and synthesizing one ormore additional status biomarker capture probes, wherein each additionalstatus biomarker capture probe has the sequence of one of the additionalstatus biomarker capture probe sequences. In some forms, the repetitiveDNA sequence loci in each additional set of repetitive DNA sequence locican independently belong to a different single one of the families ofrepetitive DNA sequence listed in, for example, Table 1, wherein therepetitive DNA sequence loci in the set of repetitive DNA sequence lociand in each additional set of repetitive DNA sequence loci belong todifferent families of repetitive DNA sequence.

In some forms, the repetitive DNA sequence loci in the each additionalset of repetitive DNA sequence loci can independently belong to a singleone of the families of repetitive DNA sequence LTR54B, MER11B, MER34B,LTR56, THE1B, HERV9, LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D,HERVK11, LTR10B, HERVK22, MER6, MER66C, MLT1G1, MER4D, and MLTD2. Insome forms, each status biomarker capture probe sequence in the set canhave a length of 100 bases or more. In some forms, each status biomarkercapture probe represented in the set of status biomarker capture probesequences can hybridize to at least 10% of the repetitive DNA sequenceloci in the selected subset of repetitive DNA sequence loci. In someforms, the set of status biomarker capture probe sequences can comprisefrom 1 to 100 status biomarker probe capture sequences. In some forms,the set of status biomarker capture probe sequences can comprise from 5to 100 status biomarker probe capture sequences. In some forms, the setof status biomarker capture probe sequences can comprise from 10 to 100status biomarker probe capture sequences. In some forms, one or more ofthe additional sets of status biomarker capture probe sequences each cancomprise from 1 to 100 status biomarker probe capture sequences. In someforms, the one or more additional sets of status biomarker capture probesequences each can comprise from 5 to 100 status biomarker probe capturesequences. In some forms, the one or more additional sets of statusbiomarker capture probe sequences each can comprise from 10 to 100status biomarker probe capture sequences.

Additional advantages of the disclosed method and compositions will beset forth in part in the description which follows, and in part will beunderstood from the description, or may be learned by practice of thedisclosed method and compositions. The advantages of the disclosedmethod and compositions will be realized and attained by means of theelements and combinations particularly pointed out in the appendedclaims. It is to be understood that both the foregoing generaldescription and the following detailed description are exemplary andexplanatory only and are not restrictive of the invention as claimed.

BRIEF DESCRIPTION OF THE DRAWINGS

The accompanying drawings, which are incorporated in and constitute apart of this specification, illustrate several embodiments of thedisclosed method and compositions and together with the description,serve to explain the principles of the disclosed method andcompositions.

FIG. 1 is divided into 3 sections, with each of the sections summarizinginformation about a subset of experiments: 10 Normal, 17 Non-TumorAdjacent or 33 Tumor. Initially, within each experiment, a subset ofprobes reporting on a particular group of repetitive elements wereaveraged to present a single methylation level per repetitive elementgroup in an experiment. Subsequently the mean methylation levels from asubset of experiments were pooled to calculate the median value plottedin the figure. The repetitive element categories are indicated on theleft side of the plot. The number in parenthesis next to each nameindicates how many probe measurements were averaged in each of theexperiments. The categories in the shaded boxes represent the results ofin-silico PCR amplification performed using the LINE-element-amplifyingprimers as described in the literature (Choi et al. Carcinogenesis 2009;Woloszynska-Read et al. Clinical Cancer Research 2008; Rago et al.Cancer research 2007; Chalitchagorn et al. Oncogene 2004; Yang et al.Nucleic Acids Res 2004; Sunami et al. Ann NY Acad Sci 2008). Thein-silico PCR was conducted as follows: first primer sequences from theliterature were aligned to the genome using FASTA. Subsequently theFASTA outputs for two complementary primers were parsed and filtered sothat only the alignments separated by 50-1500 bases were reported as thein-silico PCR amplicons. The coordinates of the amplicons were used toquery the RepBase database of repetitive elements to classify what kindof repetitive elements were amplified. Given that the primers allow foramplification of various groups of repetitive elements, the relativeamount of each was recorded for use in the subsequent step. The valuesplotted are thus based on an average of the methylation levels ofseveral repetitive elements group in an experiment, weighed according tothe relative composition of the in-silico PCR result. These weightedaverages are subsequently pooled per experiment subset to plot thesubset's median. The arrows point to the values that were generatedusing the in-silico PCR reaction. The order or repetitive elementcategories within each of the 3 sections of this figure is constant, andbased on the information content of the methylation levels of givenrepeat element category in normal and tumor experiments. The informationcontent is calculated using Shannon Entropy measure, and the categoriesare ordered so that the most informative is on the bottom. Furthermore,the 5 most informative categories of repetitive elements arehighlighted. The remaining less-informative categories are plotted ingray.

FIG. 2 represents a Random Forest List of Category importance based onMean Decreased Accuracy (left panel) and Mean Decreased Gini (rightpanel). The top 30 categories shown in the plot were selected from alist of 139,379 variables including gene probes, unique probes andrepetitive element categories.

FIG. 3 shows a multi-dimensional scaling plot of proximity of theexperiments based on the random forest classification. 1 representsNormal experiments, 2—Non-Tumor Adjacent experiments, 3 represents aTumor experiment. The distance between any 2 experiments represents thefrequency of classification into the same category based on the “forest”of 45,000 classification trees. 139,379 categories.

FIG. 4 shows Receiver-Operator Curves for Margin and Normal experiments(left panel) Tumor and Non-Tumor Adjacent experiments (right panel).Out-Of-Bag (OOB) cross validation results are shown. 139,379 categories.

FIGS. 5A-5F show a simplified diagram summarizing the steps of anexample of the disclosed methods Example 3). (A) DNA is first acquiredfrom a tissue material (B) the DNA is split into two equal aliquots (C)each of them is then digested with methylation sensitive or dependentenzymes (D) the DNA is then amplified (E) labeled and (F) hybridized toa microarray.

FIG. 6 represents examples of probe design and microarray response fortwo probes near repetitive elements. The figure shows the genomiccontext of a repetitive element, the locations of probes, CpG islands,other repeats, potential enzyme cuts as well as outcomes from 6methylation experiments. The top part was generated using the UCSCgenome browser. The top 2 boxes of both 6A and 6B are normal samples,the middle two boxes are non-tumor adjacent samples and the bottom twoboxes are tumor samples and each of the six boxes corresponds to asingle methylation experiment. The text underneath provides a summary ofa region using ASCII characters (generated using a tool ASCIIMap). The 6ASCIIMap tracks show the location of the probe (∘ and highlighted withan arrow) and ˜700 bases up- and downstream (:) which together form aregion where the probe's signal is coming from. The location of a CpGisland is marked underneath (*) as are the locations of repetitiveelements in the area (1—Line1, 2—Line2, T—LTR(MaLR), S—SINE, =—other,A—Alu, etc.). The vertical bars (|) indicate the presence of an enzymerecognition site for AciI, HHaI and McrBC enzymes respectively. Theresolution of 1 character is about 100 nucleotides. FIG. 6A shows L1PA3,the total region shown is approximately 16 kb wide and FIG. 6B showsTHE1C, the total region shown is approximately 11 kb wide.

FIG. 7 shows the four sections of the plot indicate 4 distinct classesof tissue types used for methylation profiling: Normals (10experiments), non-tumor adjacent (17 experiments), Tumors (33Experiments) and Sperm (3 replicate experiments). Each of the foursections contains the methylation levels of the same 13 categories ofrepetitive elements. Per category, the values are summarized using abox-and-whisker plot. A line within each box indicates the median value.Box boundaries are drawn based on 1^(st) and 3^(rd) quartiles. Thedashed lines extending from the box indicate the extreme values of thedistribution. Outliers, if any, are indicated by a circle. The classesand families of repetitive elements are indicated on the left of thebox-and-whisker segment. The number in parenthesis next to the categorydescription indicates the number of probes corresponding to the numberof repetitive elements uniquely probed in the genome. The order ofcategories is constant in all four of the subsections. It wasestablished based on the extent of variation in the plotteddistributions using Shannon entropy information content metric. OnlyNormal and Tumor experiments were used to calculate the Shannon'sInformation metric. For a more detailed explanation see ‘Plotting thedata’ section in Example 2. FIG. 7A shows the distribution of averagemethylation levels per category. In each of the 4 subsections of theplot the pertinent experiments contributed an average methylation levelfor all probes in proximity of a specific class of repetitive element.FIG. 7B shows the same as 7A except this time every experiment isnormalized using an average of all tumor-adjacent experiments.

FIG. 8 shows the distributions of average methylation levels perlineages of MaLR (Smit, 1993) in subsets of experiments. In each of the4 subsections of the plot, the pertinent experiments contributed anaverage methylation level for all probes in proximity of a specificclass of repetitive element indicated on the left. The values aresummarized using a box-and-whisker plot. A star next to a name indicatesthat it is primate-specific, and the estimated time of its origin in thegenome is less than 60 million years ago (MYA). Table 10 containsdetailed information about the ages of each of the subfamilies. (Paceand Feschotte, 2007; Khan et al., 2006; Batzer and Deininger, 2002;Kapitonov and Jurka, 1996).

FIG. 9 shows the average methylation levels of repetitive elementcategories per experiment. Numbers in parenthesis indicate how manyprobes were averaged per experiment (See also the ‘Plotting the Data’section in Example 2)

FIGS. 10A and 10B show the ordering within plots. Per-experiment averagemethylation levels of the most informative subset of L1P and the leastinformative probes near DNA transposons and AluSq regions. (A)Experiments are not ordered. The dotted line indicates the averagevalues of significant L1P probes in normal, non-tumor adjacent, tumorand sperm experiments (from top to bottom). (B) Experiments orderedwithin their groups based on L1P-mean(AluSq+DNA) probe values. Thedotted line indicates the average values of significant L1P probes innormal, non-tumor adjacent, tumor and sperm experiments (from top tobottom).

FIGS. 11A and 11B represent example of a per-experiment plot showingaverage methylation levels of 4 categories of genomic compartments andper-category plot showing distributions of average methylation levels of4 categories of genomic compartments, respectively. See the ‘Plottingthe Data’ section in Example 2.

FIGS. 12A-12D characterize the genomic context of the repetitive elementfamily (bin plot). The sub-plots characterize all repetitive elements ofa particular class in the human genome. The bins of plot A summarize thedistribution of CpG counts in all sequences of all repetitive elementsfrom a given lineage and 1,500 bases up˜ and downstream from the repeatin 100 base increments per bin. The distribution of CpG in the repeatbin and external bins are presented in the form of a standard box andwhisker plot, where the thick line inside the box indicates a median,the box is drawn around 25^(th) and 75^(th) percentiles, and theoutliers are indicated as dots. Plots B and C keep the binding structureof the sequence as in plot A, and show the average number of potentialenzyme cuts among all the sequences per bin normalized to the size ofthe bin. Gray lines indicate the standard deviation. Plot D is pertinentto the central bin of Plot A, it shows the distribution of sizes of allgenomic repeats of a given family which were included in the central binof plot A.

FIG. 13 shows the genomic organization of a biomarker probe LOCUScomprising a HUERS-P3 repetitive element, and two adjacent repetitiveelements. The gene identifiers, RepeatMasker and Scale information inthe figure were generated by the UCSC Genome Browser. The probecoordinates are chr17:73,126,561-73,126,611, and this position isindicated by a vertical arrow at the top of the figure. The locus is inthe vicinity of the CD300 antigen-like family member B (BC028091,CD300LB). The annotation of Repeating Elements by RepeatMasker shows aHUERS-P3 element (grey bars), interrupted by an AluY sequence (blackbar). The HUERS-P3 element is flanked on the left side by an LTR9Bsequence (dark grey bar). The two large horizontal arrows near thebottom of the figure indicate the boundaries of the locus, whichcomprises approximately 1400 bases of genomic DNA. A CpG island islocated exactly in the center of the locus, but is not shown in thefigure.

DETAILED DESCRIPTION

The disclosed method and compositions may be understood more readily byreference to the following detailed description of particularembodiments and the Example included therein and to the Figures andtheir previous and following description.

It has been discovered that the methylation status and/or level ofcertain loci in genomes can be used to assess and determine the statusof subjects, tissues, and cells. For example, it has been discoveredthat the methylation status and/or level of certain repetitive DNAsequence loci and families of repetitive DNA sequence loci candistinguish the presence, absence, and/or risk or progress toward avariety of diseases and conditions.

The DNA of most tumors has a reduced content of methylated cytosineresidues. This so-called global “hypomethylation” affects primarily DNAsequences that belong to interspersed DNA repeats. In normal humantissues, DNA repeats are predominantly methylated, consistent with therequirement to maintain genomic stability by transcriptional silencingof retroelements whose potential deleterious functions include DNAmobilization as well as the facilitation of recombination events insomatic cells. There have been a considerable number of reports oftranscriptional activation of retrotransposons in the context of loss ofDNA methylation. Expression of human endogenous retroviruses (HERVs) hasbeen detected in breast cancer (Wang-Johanning et al., 2001), ovariancancer (Menendez et al., 2004, Wang-Johanning et al., 2007), leukemiacell lines, (Patzke et al., 2002), urothelial and renal cell carcinomas(Florl et al., 1999). Increased transcriptional expression of HERV-K hasbeen reported in teratocarcinoma (Löwer et al., 1984; Herbst et al.,1998), breast cancer cells and adjacent tissues (Wang-Johanning et al.,2003, Golan et al., 2008), and in melanoma (Muster et al., 2003; Büscheret al., 2006, Serafino et al., 2009). Stauffer et al. (2004) usedmassively parallel signature sequencing (MPSS) to define the number andtype of transcripts of endogenous retroviruses of the LTR family invarious cancers. This study reported that HERV-H, a relatively youngretrotransposon, was expressed in cancers of the intestine, bone marrow,bladder and cervix, and was more highly expressed than the otherfamilies in cancers of the stomach, colon and prostate. Recently Alveset al. (2008) have reported that a specific HERVH element present in theX chromosome is selectively transcribed in 60% of colon cancers, and ina high proportion of metastatic colon cancers. There is evidence forcontext-specific induction of LINE-1 transcription during oxidativestress (Teneng et al., 2007). In a relatively large study of squamoushead and neck carcinomas, Smith et al. (2007) reported that the DNAmethylation level of LINE-1 elements was significantly reduced, andcorrelated with environmental insults such as alcohol use and smoking,as well as tumor stage.

Disclosed are methods and compositions of assessing one or more statusesof a subject. Also disclosed are methods and compositions of identifyingstatus biomarkers associated with a status of a subject. Also disclosedare sets of one or more status biomarkers. Also disclosed are methodsand compositions of producing status biomarker capture probes.

It is to be understood that the disclosed method and compositions arenot limited to specific synthetic methods, specific analyticaltechniques, or to particular reagents unless otherwise specified, and,as such, may vary. It is also to be understood that the terminology usedherein is for the purpose of describing particular embodiments only andis not intended to be limiting.

Materials

Disclosed are materials, compositions, and components that can be usedfor, can be used in conjunction with, can be used in preparation for, orare products of the disclosed method and compositions. These and othermaterials are disclosed herein, and it is understood that whencombinations, subsets, interactions, groups, etc. of these materials aredisclosed that while specific reference of each various individual andcollective combinations and permutation of these compounds may not beexplicitly disclosed, each is specifically contemplated and describedherein. For example, if a status biomarker is disclosed and discussedand a number of modifications that can be made to a number of moleculesincluding the status biomarker are discussed, each and every combinationand permutation of status biomarker and the modifications that arepossible are specifically contemplated unless specifically indicated tothe contrary. Thus, if a class of molecules A, B, and C are disclosed aswell as a class of molecules D, E, and F and an example of a combinationmolecule, A-D is disclosed, then even if each is not individuallyrecited, each is individually and collectively contemplated. Thus, isthis example, each of the combinations A-E, A-F, B-D, B-E, B-F, C-D,C-E, and C-F are specifically contemplated and should be considereddisclosed from disclosure of A, B, and C; D, E, and F; and the examplecombination A-D. Likewise, any subset or combination of these is alsospecifically contemplated and disclosed. Thus, for example, thesub-group of A-E, B-F, and C-E are specifically contemplated and shouldbe considered disclosed from disclosure of A, B, and C; D, E, and F; andthe example combination A-D. This concept applies to all aspects of thisapplication including, but not limited to, steps in methods of makingand using the disclosed compositions. Thus, if there are a variety ofadditional steps that can be performed it is understood that each ofthese additional steps can be performed with any specific embodiment orcombination of embodiments of the disclosed methods, and that each suchcombination is specifically contemplated and should be considereddisclosed.

A. Status Biomarkers

Status biomarkers as used herein refer to nucleic acid sequences in agenome the methylation levels of which can be used to assess the statusof a subject and/or one or more diseases, conditions, and/or states in asubject. Status biomarkers also include groups of such nucleic acidsequences, in the case of collective status biomarkers. Example 2provides an example of identification of biomarkers that can be used toidentify status biomarkers and all of the examples provide examples ofhow to identify status biomarkers and use status biomarkers forassessing the status of subjects and samples. Biomarkers from whichstatus biomarkers are selected can be referred to as prospective statusbiomarkers.

Useful nucleic acid sequences for use as status biomarkers and nucleicacid sequences from which status biomarkers can be selected can includeCpG islands or CpG islets and a unique sequence in proximity to a CpGisland or CpG islet. Thus, status biomarkers and prospective statusbiomarkers can be loci having a unique sequence in proximity to a CpGisland or CpG islet. CpG islands and CpG islets are described below andelsewhere herein. Proximity to a CpG island or CpG islet is describedbelow and elsewhere herein. By unique sequence, in the context of statusbiomarkers, is meant a sequence of sufficient length and having anucleotide sequence distinctive enough to be uniquely in the genomeidentified by a probe. For example, nucleic acid sequences of or atleast 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90,95, or 100 nucleotides in length can be used as unique sequences. Uniquesequences can be identified by, for example, analysis of a genomesequence or by analysis of probe hybridization. The examples ofselection of unique sequences herein make use of analysis of the humangenome sequence. Status biomarkers are referred to herein by differentterms such as variables, classifiers, and category classifiers.

In some forms of the sets of one or more status biomarkers the statusbiomarkers can comprise, for example, nucleic acid sequences in agenome. In some forms, the status biomarkers can comprise nucleic acidsequences in the genome of the species to which the subject belongs. Insome forms, the nucleic acid sequences can be in proximity to CpGislands or islets. CpG islands and CpG islets are one significantlocation of DNA methylation that can affect gene expression. Example 2describes the criteria used for selecting CpG islands and CpG islets,which was more lax than standard selection criteria. The CpG islands orislets can comprise nucleic acid regions of or greater than, forexample, 20, 30, 40, 40, 60, 70, 80, 90, 100, 120, 140, 160, 180, 200,220, 240, 260, 280, 300, 350, 400, or 500 nucleotides in length thatcontain a minimum of 5, 6, 7, 8, 9, 10, 11, or 12 CpG residues. The CpGislands and islets can have a ratio of CG content to GC content of orgreater than, for example, 0.2, 0.3, 0.35, 0.38, 0.4, 0.40, 0.42, 0.43,0.44, 0.45, 0.46, 0.47, 0.48, 0.49, 0.5, 0.50, 0.51, 0.52, 0.53, 0.54,0.55, 0.56, 0.58, 0.59, 0.6, 0.60, 0.62, 0.65, 0.7, or 0.8. Thesequence(s) that define the status biomarkers can be considered to be inproximity to CpG islands or islets when they are within 800, 850, 900,950, 1000, 1050, 1100, 1150, 1200, 1250, 1300, 1350, 1400, 1450, 1500,1600, 1700, 1800, 1900, or 2000 bases of a CpG island or islet.

569 repetitive DNA sequence families were identified from among the lociidentified as CpG island- or CpG islet-containing loci as described inExample 2. Table 18 is a list of these repetitive DNA sequence families.Among the 569 repetitive element families comprising the full set ofrepetitive DNA sequence status biomarkers, a subset of 138 wasidentified that are most effective as classifiers. This subset wasgenerated by merging the top 75 categories identified by a Random Forestanalysis with another 75 categories that were the best performers usinga Support Vector Machine classifier. This produced the list of Top 138status biomarkers (Table 1). Each of these families represents multiplerepetitive DNA sequence loci. Selected loci belonging to these familiescan be probed via unique sequences in the loci. Useful loci for the Top138 families are specifically identified in Table 15 by listing of startand ending coordinates of example probe sequences in the loci. The lociidentified by these probe sequences can be assessed, probed, detected,etc. according to the disclosed methods. The probe sequences identifiedin Table 15 are only examples of probe sequences that can be used todetect and assess the identified loci.

In some forms, one or more of the status biomarkers can overlap with allor part of a CpG island or islet. In some forms, the one or more of thestatus biomarkers can comprise a probe binding site, wherein the probebinding site of the one or more of the status biomarkers is specific fora probe. Probe binding sites can be, for example, all or a portion of aunique sequence in the status biomarker. In some forms, one or more ofthe probes can be specific for a repetitive DNA sequence locus, whereinthe repetitive DNA sequence locus comprises one or more repetitive DNAsequences, wherein independently for each of the one or more of theprobes one or more of the repetitive DNA sequences belongs to a familyof repetitive DNA sequences listed in, for example, Table 1.

A repetitive DNA sequence is a DNA sequence that is repeated numeroustimes in a genome. Repetitive DNA sequences can also be referred to asrepetitive DNA elements, repetitive sequences, repetitive elements, andrepetitive DNA sequence elements. Repetitive DNA sequences can berepeated in different patterns in the genome, such as interspersedrepetitive DNA sequences and tandem repetitive DNA sequences. Arepetitive DNA sequence locus refers to a locus that includes one ormore repetitive DNA sequences. An example of a repetitive DNA sequencelocus is shown in FIG. 13. Repetitive DNA sequences have been classifiedinto different families, sub-families, classes, subclasses, etc. ofrepetitive DNA elements. Although different such groups of repetitiveDNA sequences can have different meanings, for convenience, all suchgroups and classifications are referred to herein as families or groups.Such reference should be considered to refer to all the different typesof groups and classifications unless the context clearly indicatesotherwise. Repetitive DNA sequence loci that comprise a given repetitiveDNA sequence can be said to belong to the repetitive DNA sequence.Repetitive DNA sequence loci that comprise a repetitive DNA sequencethat belongs to a given repetitive DNA sequence family can be said tobelong to the repetitive DNA sequence family. In some forms, each probecan be specific for a repetitive DNA sequence locus, whereinindependently for each probe one or more of the repetitive DNA sequencesbelongs to a family of repetitive DNA sequences such as the repetitiveDNA sequence families listed in, for example, Table 1, Table 12, orTable 13.

In some forms, one or more of the probes can be specific for arepetitive DNA sequence locus, wherein the repetitive DNA sequence locuscomprises one or more repetitive DNA sequences, wherein for one or moreof the probes one or more of the repetitive DNA sequences is aninterspersed repeat element. In some forms, each probe can be specificfor a repetitive DNA sequence locus, wherein for each probe one or moreof the repetitive DNA sequences is an interspersed repeat element.

In some forms, one or more of the status biomarkers can comprise a PCRamplicon. A PCR amplicon is a region of nucleic acid including andbetween the binding sites of PCR primers. PCR amplicons can be said tobe defined by the binding sites of the primers and by the primersthemselves. In some forms, the PCR amplicon of each of the one or moreof the status biomarkers can be defined by a first primer specific for asingle one of the status biomarkers and a second primer. A primerspecific for a status biomarker refers to a primer that can bind to asequence in, and prime replication of, the status biomarker. A primerspecific for a repetitive DNA sequence refers to a primer that can bindto a sequence in, and prime replication of, the repetitive DNA sequence.In some forms, the PCR amplicon of each of the one or more of the statusbiomarkers can be defined by the same first primer specific for a firsttype of repetitive DNA sequence and a second primer, wherein the secondprimer is specific for a second type of repetitive DNA sequence, whereinthe second primer is the same for some and different for some of the oneor more of the status biomarkers. In some forms, the first primer can bespecific for one of the families of repetitive DNA sequences listed inTable 16 or 17, wherein independently for each of the one or more of thestatus biomarkers the second primer is specific for a family ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. A primerspecific for a family of repetitive DNA sequence refers to a primer thatcan bind to a sequence in, and prime replication of, one or morerepetitive DNA sequences in the family of repetitive DNA sequences.

In some forms, one or more of the status biomarkers can comprise one ormore repetitive DNA sequences, wherein independently for each of the oneor more of the status biomarkers that comprise repetitive DNA sequencesone or more of the repetitive DNA sequences belongs to a family ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. By independentlyis meant that, for each component in the group referred to, the specificidentity of each component can be the same or different from thespecific identity of any other of the components in the group. Forexample, in the group of status biomarkers above each different statusbiomarker can comprise the same or a different repetitive DNA sequenceas any of the other status biomarkers in the group. In some forms, eachstatus biomarker can comprise a repetitive DNA sequence, whereinindependently for each of the status biomarkers the repetitive DNAsequence belongs to a family of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 1, Table12, or Table 13. In some forms, one or more of the status biomarkers cancomprise one or more repetitive DNA sequences, wherein for one or moreof the status biomarkers that comprise repetitive DNA sequences one ormore of the repetitive DNA sequences is an interspersed repeat element.In some forms, each status biomarker can comprise a repetitive DNAsequence, wherein for each status biomarker the repetitive DNA sequenceis an interspersed repeat element.

The disclosed components, such as status biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, and collective prospective status biomarkers, can be used insets or groups. For example, sets of biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, and collective prospective status biomarkers can include,for example, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18,19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35, 36, 38, 40,42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 110,120, 130, 140, 150, 160, 170, 180, 190, 200, 220, 240, 250, 260, 280,300, 320, 340, 350, 360, 380, 400, 420, 440, 450, 460, 480, 500, 550,600, 650, 700, 750, 800, 850, 900, 950, 1000, 1100, 1200, 1300, 1400,1500, 1600, 1700, 1800, 1900, 2000, 2200, 2400, 2500, 2600, 2800, 3000,3200, 3400, 3500, 3600, 3800, 4000, 4200, 4400, 4500, 4600, 4800, 5000,5500, 6000, 6500, 700, 7500, 8000, 8500, 9000, 9500, 10,000, 11,000,12,000, 13,000, 14,000, 15,000, 16,000, 17,000, 18,000, 19,000, 20,000,22,000, 24,000, 25,000, 26,000, 28,000, 30,000, 32,000, 34,000, 35,000,36,000, 38,000, 40,000, 42,000, 44,000, 45,000, 46,000, 48,000, 50,000,55,000, 60,000, 65,000, 70,000, 75,000, 80,000, 85,000, 90,000, 95,000,100,000, 110,000, 120,000, 130,000, 140,000, 150,000, 160,000, 170,000,180,000, 190,000, 200,000, 210,000, 220,000, 230,000, 240,000, 250,000,260,000, 270,000, 280,000, 290,000, 300,000, 320,000, 340,000, 350,000,360,000, 380,000, 400,000 or more biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, or collective prospective status biomarkers, respectively.For collective biomarkers, the group of biomarkers making up thecollective biomarker can include a number of individual biomarkers asdescribed herein.

As another example, sets of biomarker loci, repetitive DNA sequences,repetitive DNA loci, biomarkers, status biomarkers prospective statusbiomarkers, collective biomarkers, collective status biomarkers, andcollective prospective status biomarkers can include, for example,exactly or at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16,17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35, 36,38, 40, 42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100,110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 220, 240, 250, 260,280, 300, 320, 340, 350, 360, 380, 400, 420, 440, 450, 460, 480, 500,550, 600, 650, 700, 750, 800, 850, 900, 950, 1000, 1100, 1200, 1300,1400, 1500, 1600, 1700, 1800, 1900, 2000, 2200, 2400, 2500, 2600, 2800,3000, 3200, 3400, 3500, 3600, 3800, 4000, 4200, 4400, 4500, 4600, 4800,5000, 5500, 6000, 6500, 700, 7500, 8000, 8500, 9000, 9500, 10,000,11,000, 12,000, 13,000, 14,000, 15,000, 16,000, 17,000, 18,000, 19,000,20,000, 22,000, 24,000, 25,000, 26,000, 28,000, 30,000, 32,000, 34,000,35,000, 36,000, 38,000, 40,000, 42,000, 44,000, 45,000, 46,000, 48,000,50,000, 55,000, 60,000, 65,000, 70,000, 75,000, 80,000, 85,000, 90,000,95,000, 100,000, 110,000, 120,000, 130,000, 140,000, 150,000, 160,000,170,000, 180,000, 190,000, 200,000, 210,000, 220,000, 230,000, 240,000,250,000, 260,000, 270,000, 280,000, 290,000, 300,000, 320,000, 340,000,350,000, 360,000, 380,000, 400,000 biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, or collective prospective status biomarkers, respectively.

As another example, sets of biomarker loci, repetitive DNA sequences,repetitive DNA loci, biomarkers, status biomarkers prospective statusbiomarkers, collective biomarkers, collective status biomarkers, andcollective prospective status biomarkers can include, for example, anyrange of from 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17,18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35, 36, 38,40, 42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100,110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 220, 240, 250, 260,280, 300, 320, 340, 350, 360, 380, 400, 420, 440, 450, 460, 480, 500,550, 600, 650, 700, 750, 800, 850, 900, 950, 1000, 1100, 1200, 1300,1400, 1500, 1600, 1700, 1800, 1900, 2000, 2200, 2400, 2500, 2600, 2800,3000, 3200, 3400, 3500, 3600, 3800, 4000, 4200, 4400, 4500, 4600, 4800,5000, 5500, 6000, 6500, 700, 7500, 8000, 8500, 9000, 9500, 10,000,11,000, 12,000, 13,000, 14,000, 15,000, 16,000, 17,000, 18,000, 19,000,20,000, 22,000, 24,000, 25,000, 26,000, 28,000, 30,000, 32,000, 34,000,35,000, 36,000, 38,000, 40,000, 42,000, 44,000, 45,000, 46,000, 48,000,50,000, 55,000, 60,000, 65,000, 70,000, 75,000, 80,000, 85,000, 90,000,95,000, 100,000, 110,000, 120,000, 130,000, 140,000, 150,000, 160,000,170,000, 180,000, 190,000, 200,000, 210,000, 220,000, 230,000, 240,000,250,000, 260,000, 270,000, 280,000, 290,000, 300,000, 320,000, 340,000,350,000, 360,000, or 380,000 biomarker loci, repetitive DNA sequences,repetitive DNA loci, biomarkers, status biomarkers prospective statusbiomarkers, collective biomarkers, collective status biomarkers, orcollective prospective status biomarkers, respectively, to 3, 4, 5, 6,7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25,26, 27, 28, 29, 30, 32, 34, 35, 36, 38, 40, 42, 44, 45, 46, 48, 50, 55,60, 65, 70, 75, 80, 85, 90, 95, 100, 110, 120, 130, 140, 150, 160, 170,180, 190, 200, 220, 240, 250, 260, 280, 300, 320, 340, 350, 360, 380,400, 420, 440, 450, 460, 480, 500, 550, 600, 650, 700, 750, 800, 850,900, 950, 1000, 1100, 1200, 1300, 1400, 1500, 1600, 1700, 1800, 1900,2000, 2200, 2400, 2500, 2600, 2800, 3000, 3200, 3400, 3500, 3600, 3800,4000, 4200, 4400, 4500, 4600, 4800, 5000, 5500, 6000, 6500, 700, 7500,8000, 8500, 9000, 9500, 10,000, 11,000, 12,000, 13,000, 14,000, 15,000,16,000, 17,000, 18,000, 19,000, 20,000, 22,000, 24,000, 25,000, 26,000,28,000, 30,000, 32,000, 34,000, 35,000, 36,000, 38,000, 40,000, 42,000,44,000, 45,000, 46,000, 48,000, 50,000, 55,000, 60,000, 65,000, 70,000,75,000, 80,000, 85,000, 90,000, 95,000, 100,000, 110,000, 120,000,130,000, 140,000, 150,000, 160,000, 170,000, 180,000, 190,000, 200,000,210,000, 220,000, 230,000, 240,000, 250,000, 260,000, 270,000, 280,000,290,000, 300,000, 320,000, 340,000, 350,000, 360,000, 380,000, or400,000 biomarker loci, repetitive DNA sequences, repetitive DNA loci,biomarkers, status biomarkers prospective status biomarkers, collectivebiomarkers, collective status biomarkers, or collective prospectivestatus biomarkers, respectively.

The methylation state of any number (such as the numbers and rangesdescribed above) of, for example, biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, or collective prospective status biomarkers can bedetermined. In some forms, the methylation state of more than 100biomarkers can be determined. In some forms, the methylation state ofmore than 1000 biomarkers can be determined. In some forms, themethylation state of more than 10,000 biomarkers can be determined. Insome forms, the methylation state of more than 100,000 biomarkers can bedetermined. In some forms, the methylation state of more than 200,000biomarkers can be determined. In some forms, the biomarker loci,repetitive DNA sequences, repetitive DNA loci, biomarkers, statusbiomarkers prospective status biomarkers, collective biomarkers,collective status biomarkers, and collective prospective statusbiomarkers can comprise a set of biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, or collective prospective status biomarkers, respectively.The set can comprise any number (such as the numbers and rangesdescribed above) of, for example, biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, or collective prospective status biomarkers. In some forms,the set can comprise more than 100 status biomarkers. In some forms, theset can comprise more than 1000 status biomarkers. In some forms, theset can comprise more than 10,000 status biomarkers. In some forms, theset can comprise more than 100,000 status biomarkers. In some forms, theset can comprise more than 200,000 status biomarkers.

In some forms, a plurality of the biomarkers can independently belong toone or more status biomarker families, wherein each biomarker in eachstatus biomarker family comprises one or more repetitive DNA sequencesthat belong to a single family of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 1, Table12, or Table 13. In some forms, a plurality of biomarkers canindependently belong to 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15,16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35,36, 38, 40, 42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95,100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 220, 240, 250,260, 280, 300, 320, 340, 350, 360, 380, 400, 420, 440, 450, 460, 480,500, 550, 600, 650, 700, 750, 800, 850, 900, 950, 1000, 1100, 1200 ormore status biomarker families. In some forms, a plurality of biomarkerscan independently belong to three or more status biomarker families. Insome forms, a plurality of biomarkers can independently belong to fouror more status biomarker families. In some forms, a plurality ofbiomarkers can independently belong to five or more status biomarkerfamilies. In some forms, a plurality of biomarkers can independentlybelong to ten or more status biomarker families. In some forms, aplurality of biomarkers can independently belong to twenty or morestatus biomarker families.

In some forms, 100 or more biomarkers can belong to one or more of thestatus biomarker families. In some forms, 100 or more biomarkers canbelong to each of the status biomarker families. In some forms, 200 ormore biomarkers can belong to one or more of the status biomarkerfamilies. In some forms, 200 or more biomarkers can belong to each ofthe status biomarker families. In some forms, 300 or more biomarkers canbelong to one or more of the status biomarker families. In some forms,300 or more biomarkers can belong to each of the status biomarkerfamilies. In some forms, 400 or more biomarkers can belong to one ormore of the status biomarker families. In some forms, the 400 or morebiomarkers can belong to each of the status biomarker families. In someforms, a plurality of, for example, biomarker loci, repetitive DNAsequences, repetitive DNA loci, biomarkers, status biomarkersprospective status biomarkers, collective biomarkers, collective statusbiomarkers, and collective prospective status biomarkers canindependently belong to 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15,16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35,36, 38, 40, 42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95,100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 220, 240, 250,260, 280, 300, 320, 340, 350, 360, 380, 400, 420, 440, 450, 460, 480,500, 550, 600, 650, 700, 750, 800, 850, 900, 950, 1000, 1100, 1200 ormore families of biomarker loci, repetitive DNA sequences, repetitiveDNA loci, biomarkers, status biomarkers prospective status biomarkers,collective biomarkers, collective status biomarkers, or collectiveprospective status biomarkers, respectively.

In some forms, the status biomarkers can comprise a set of statusbiomarkers. In some forms, the members of the set of status biomarkerscan be status biomarkers that indicate the status of one or morespecific statuses. In some forms, the one or more specific statuses cancomprise, for example, wellness, level of health, risk to wellness, riskto level of health, status of the genome, genomic instability, aging,risk of aging, cancer, risk of cancer, head and neck cancer, risk ofhead and neck cancer, breast cancer, risk of breast cancer, lung cancer,risk of lung cancer, prostate cancer, risk of prostate cancer, coloncancer, risk of colon cancer, esophageal cancer, risk of esophagealcancer, ovarian cancer, risk of ovarian cancer, liver cancer, risk ofliver cancer, pancreatic cancer, risk of pancreatic cancer, skin cancer,risk of skin cancer, melanoma, risk of melanoma, lymphoma, risk oflymphoma, leukemia, risk of leukemia, cervical cancer, risk of cervicalcancer, cervical dysplasia, risk of cervical dysplasia, cervicalintraepithelial neoplasia, risk of cervical intraepithelial neoplasia,tumor burden, stress response, diabetes, risk of diabetes, heartdisease, risk of heart disease, and/or response to treatment.

In some forms, the one or more specific statuses can comprise thepresence of a disease or condition. In some forms, the one or morespecific statuses can comprise, for example, a lack of wellness, lowlevel of health, risk to wellness, risk to level of health, poor statusof the genome, genomic instability, aging, risk of aging, cancer, riskof cancer, head and neck cancer, risk of head and neck cancer, breastcancer, risk of breast cancer, lung cancer, risk of lung cancer,prostate cancer, risk of prostate cancer, colon cancer, risk of coloncancer, esophageal cancer, risk of esophageal cancer, ovarian cancer,risk of ovarian cancer, liver cancer, risk of liver cancer, pancreaticcancer, risk of pancreatic cancer, skin cancer, risk of skin cancer,melanoma, risk of melanoma, lymphoma, risk of lymphoma, leukemia, riskof leukemia, cervical cancer, risk of cervical cancer, cervicaldysplasia, risk of cervical dysplasia, cervical intraepithelialneoplasia, risk of cervical intraepithelial neoplasia, tumor burden,stress response, diabetes, risk of diabetes, heart disease, and/or riskof heart disease.

1. Lists of Status Biomarkers

Analysis of methylation levels in biological samples relevant to subjectstatus (for example, normal, margin, tumor) of loci having CpG islandsor CpG islets as described herein resulted in identification of variousloci showing significant differences in methylation levels based ondifferent status. Such loci are a useful form of status biomarker.Status biomarkers can be grouped in various ways. One useful way togroup status biomarkers is into families of repetitive DNA sequences towhich the status marker belongs. As used herein, a status biomarkerbelongs to a repetitive DNA sequence family (or category, orsubcategory, or class) if the status biomarker comprises a repetitiveDNA sequence belonging to that repetitive DNA sequence family (orcategory, or subcategory, or class). Loci analyzed according to themethods described herein can also be grouped in various ways. One usefulway to group loci is into families of repetitive DNA sequences to whichthe locus belongs. As used herein, a locus belongs to a repetitive DNAsequence family (or category, or subcategory, or class) if the locuscomprises a repetitive DNA sequence belonging to that repetitive DNAsequence family (or category, or subcategory, or class). Groups ofstatus biomarkers and groups of loci can themselves be considered statusbiomarkers. For example, a group of status biomarkers belonging to theLTR54B family of repetitive DNA sequences can be a status biomarker.Such status biomarkers that comprise a group of components (such as agroup of individual status biomarkers) can be referred to as acollective status biomarker. The collective status biomarker comprisingstatus biomarkers belonging to the LTR54B family of repetitive DNAsequences can be referred to as a LTR54B family status biomarker.Collective status biomarkers are useful when determining a collectiveproperty of the individual status biomarkers in the group of statusbiomarkers, such as the average methylation of the individual loci thatmake up the status biomarkers in a group of status biomarkers. Statusbiomarkers are referred to herein by different terms such as variables,classifiers, and category classifiers.

Various lists of such status biomarker markers (both individual andcollective) are presented herein. The lists below are lists ofcollective status biomarkers (groups of status biomarkers) determined toexhibit showing significant differences in methylation levels based ondifferent status of the tissue (normal, margin, tumor).

The first two lists below arose from utilizing a list of 569 variables(collective status biomarkers) (listed in Table 18), each comprising theaverage methylation value of all members of a family of repetitiveelements that were probed in the microarrays. Each case (a case being abiological sample; 62 total samples were probed) was associated with acorresponding list of 569 values generated by the microarray analysis.After all 62 cases were analyzed using a statistical tool forclassification (Support Vector Machine (SVM) or, alternatively, RandomForrest) two different lists emerged that yield the best classificationresults (that is, best identify the status of the case based on themethylation level). The status classification is the same in bothexperiments: normal tissue sample, vs. tumor tissue sample, vs. nontumoradjacent tissue sample. Both status classification runs were supervised,in the sense that the assignment of each sample (normal, tumor, ormargin) was made by a pathologist. The resulting lists are not the same,since different combinations of variable are capable of yielding areasonably good classifier, and particularly because there are many morevariables (569) than there are cases (62). The third list below is theunion of the top 75 categories in the first two lists. The resultinglist of 138 categories is referred to herein as the Top 138 categories(or status biomarkers or repetitive DNA sequence families).

i. List of Top 75 Classifier Categories Obtained Using SVM Analysis, byRank

LTR54B, MER11B, U1, MER34B, LTR56, THE1B-int, HERV9, LTR14C, HERVFH21,LTR6B, LTR46, centr, MLT1D-int, MER67D, HERVK11, PABL_B, MSR1, AluYa5/8,LTR10B, HERVK22, GSAT, LTR10B1, LTR17, LTR51, MER11A, Other, L1PA12,ERVL-B4, HERVK14, LTR29, LTR6A, ALR/Alpha, LTR48B, MER105, MER67A,HUERS-P1, LTR7B, L1PB1, L1PA15-16, LTR28, MSTB-int, LTR45B, LTR7Y,HERVL18, LTR30, HERVK9, LTR45C, LTR47A, THE1C, LTR66, SST1, MER34B-int,LTR65, MER44D, MER57A-int, HUERS-P2, MER6A, MER50B, MER41E, 7SK,HERVP71A, L1PBa1, MER44C, GSATII, LTR1B, LTR7, MER91C, LTR22, Harlequin,MLT1F1, L1M3f, THE1B, HUERS-P3, MER92B, Charlie3

ii. List of Top 75 Classifier Categories Obtained Using Random ForestAnalysis, by Rank

MER67D, MER6, ERVL, MER66C, HUERS-P3, MLT1G1, MER4D, MLT2D, THE1B,MLT1A1, MER11B, Charlie5, MLT2B3, MER50B, MER70A, Charlie3, MER50, LTR2,MLT1A, HERVL, LTR33A, MSTB-int, Cheshire, MSTA, MER51B, MLT2B2, MSTC,LTR9B, LTR14B, HUERS-P2, MSTB1, MSTD, LTR52, LTR8, LTR8A, MER92B, LTR22,MER51A, LTR36, LTR54B, PABL_A, MER4D1, AcHobo, LTR48, MLT1A0, LTR1B,MSTB, MER11D, LTR19A, MLT1E2, MER115, MER11A, MER34C, THE1C, MLT2B1,L1PA10, MER4A1, MLT1E, MLT2B4, LTR10B, L1MA7, HERVFH21, LTR5, THE1D,L1MA1, LTR9, MER63A, LTR5A, L1PB4, ERVL-B4, MLT1F, MLT2A2, LTR14,HERVK9, MER11C.

iii. List of Top 138 Classifier Categories, by Rank

LTR54B, MER67D, MER11B, MER6, ERVL, U1, MER34B, MER66C, HUERS-P3, LTR56,MLT1G1, THE1B-int, HERV9, MER4D, LTR14C, MLT2D, HERVFH21, THE1B, LTR6B,MLT1A1, LTR46, centr, Charlie5, MLT1D-int, MLT2B3, MER50B, HERVK11,MER70A, Charlie3, PABL_B, MER50, MSR1, AluYa5/8, LTR2, LTR10B, MLT1A,HERVK22, HERVL, GSAT, LTR33A, LTR10B1, MSTB-int, Cheshire, LTR17, LTR51,MSTA, MER11A, MER51B, MLT2B2, SVA, SVA_A, SVA_B, SVA_C, SVA_D, SVA_E,SVA_F, L1PA12, MSTC, ERVL-B4, LTR9B, HERVK14, LTR14B, HUERS-P2, LTR29,LTR6A, MSTB1, ALR/Alpha, MSTD, LTR48B, LTR52, LTR8, MER105, LTR8A,MER67A, HUERS-P1, MER92B, LTR22, LTR7B, L1PB1, MER51A, L1PA15-16, LTR36,LTR28, PABL_A, LTR45B, MER4D1, AcHobo, LTR7Y, HERVL18, LTR48, LTR30,MLT1A0, HERVK9, LTR1B, LTR45C, MSTB, LTR47A, MER11D, LTR19A, THE1C,LTR66, MLT1E2, MER115, SST1, MER34B-int, LTR65, MER34C, MER44D,MER57A-int, MLT2B1, L1PA10, MER4A1, MER6A, MLT1E, MER41E, MLT2B4, 7SK,HERVP71A, L1MA7, L1PBa1, LTR5, MER44C, GSATII, THE1D, L1MA1, LTR7, LTR9,MER63A, MER91C, LTR5A, Harlequin, L1PB4, MLT1F1, L1M3f, MLT1F, MLT2A2,LTR14, MER11C.

569 repetitive DNA sequence families were identified from among the lociidentified as CpG island- or CpG islet-containing loci as described inExample 2. Table 18 is a list of these repetitive DNA sequence families.Among the 569 repetitive element families comprising the full set ofrepetitive DNA sequence status biomarkers, a subset of 138 wasidentified that are most effective as classifiers. This subset wasgenerated by merging the top 75 categories identified by a Random Forestanalysis with another 75 categories that were the best performers usinga Support Vector Machine classifier. This produced the list of Top 138status biomarkers (Table 1). A Random Forest classification analysis wasperformed utilizing the set of Top 138 status biomarkers, and a secondone utilizing the remainder of the 569 (a subset of 431). The list ofthis subset of 431 status biomarkers can be derived by eliminating theTop 138 status biomarkers in Table 1 from the list of 569 statusbiomarkers in Table 18. Random Forest analysis using the top 138 statusbiomarkers gave a classification error of 8.1%. The Receiver OperatorCharacteristic curves for this analysis gave an AUC of 1 for marginversus normal and an AUC of 0.91 for tumor versus margin. The secondRandom Forest analysis was performed using the remaining 431 statusbiomarkers. The classification error in this analysis was 19.0%. Thus,the Top 138 status biomarkers are significantly better for assessing thestatus of the samples and subjects than the remaining status biomarkers.In a separate experiment using SVM analysis, the superior performance ofthe top 138 status biomarkers compared to the remaining 431 variableswas confirmed. These results provide an objective metric for claimingsuperior utility of the top 138 biomarkers for assessing status ofsubjects.

The utility of the Status Biomarkers for distinguishing dysplasia fromcancer was optimized by performing a classification analysis that doesnot include the data from the normal samples, and which can be called anontumor margin vs. tumor classification. Taking the 569 repetitiveelement categories as variables (Table 18), classification of margin vs.tumor using Random Forest was performed, and the best 75 variables weresaved. Then, again taking the 569 repetitive element categories asvariables, classification of margin vs. tumor using the Support vectormachine was performed, and the best 75 variables were saved. The unionof the best 75 RF variables and the best 75 SVM variables was thencalculated, and this yielded 137 variables, which are called the Topperforming variables for margin vs. tumor classification (Table 12).

The Top 137 variables were used to perform an RF classification, whichyielded a classification error of 9.6%. Using the remaining 432variables yielded a classification error of 17%, confirming the superiorperformance of the Top 137 variables.

TABLE 12 Top 137 performing variables for tumor versus margin in rankorder. 1. MER50B 2. MER94 3. LTR19A 4. MLT2B3 5. AcHobo 6. MER67A 7.HERV16 8. LTR14C 9. L1MCb 10. LTR36 11. HERVL40 12. L1MC3 13. HERVL 14.LTR56 15. MER57A-int 16. LTR23 17. MLT1E2 18. ALR/Alpha 19. MER57A 20.L1MA9 21. LTR27 22. LTR51 23. L1PA13 24. MER34 25. HERV9 26. MER11A 27.MER102b 28. THE1B-int 29. L1P2 30. MER31B 31. L1MD1 32. MER91A 33.HSMAR1 34. MER34B 35. FLAM_A 36. LTR1D 37. L1MC1 38. MLT1B 39. Charlie340. LTR54B 41. HERVL18 42. L1MB4 43. LTR26 44. MER90a 45. U1 46. MSTC47. MER106B 48. Tigger1 49. LTR9B 50. MER11D 51. L1MA5A 52. MER93B 53.L1MB1 54. LTR10B 55. MIR3 56. PRIMA4-int 57. HERVK11 58. THE1B 59.MER63D 60. L1P3 61. MER119 62. L1MC2 63. LTR18B 64. LTR9 65. MER6 66.MLT1L 67. MLT2D 68. MER44B 69. MER50 70. tRNA 71. MLT1E 72. HERV35I 73.L1PA6 74. MLT1A0 75. L1MD 76. MER69B 77. L1PB2 78. MER21A 79. Tip100 80.LTR26B 81. L1ME2 82. L1PA15 83. ERVL 84. MER81 85. L1P5 86. LTR16B 87.ERVK 88. LTR6B 89. HERVL-A1 90. LTR24C 91. L1MA10 92. LTR16A 93. L1M4b94. MER46B 95. L1P1 96. MSR1 97. HUERS-P2 98. L1P4 99. LTR12D 100.MER34B-int 101. LTR12_(—) 102. L1M3d 103. L1PA3 104. LTR2B 105. MER65D106. MLT1E1 107. MLT1J2 108. AluSg/x 109. L3b 110. LTR5_Hs 111. AluYa8112. MER110A 113. AluYa5/8 114. L1PA2 115. L1MA5 116. MER91C 117. LTR67118. MER21-int 119. HAL1 120. MER63A 121. LTR10B1 122. MIRb 123. L1PBa1124. SST1 125. Charlie10 126. Tigger7 127. AluYa5 128. MSTA-int 129.L1PA7 130. LTR22C 131. LTR54 132. MER50-int 133. HERVK14 134. HUERS-P3135. MER77 136. MLT1A 137. THE1C

The overlap between the Top 138 Variables (Table 1) that are the bestclassifiers for normal vs. margin vs. tumor and the Top 137 categories(Table 12) that are the best classifiers for margin vs. tumor wascalculated. The comparison shows that only 48 variables are common toboth lists and thus are good classifiers for both tumor-margin andtumor-margin-normal comparison experiments. The 48 common variables arelisted below in Table 13.

TABLE 13 List of 48 variables common to Top 137 and Top 138. ALR/AlphaAluYa5/8 AcHobo Charlie3 ERVL HERV9 HERVK11 HERVK14 HERVL HERVL18HUERS-P2 HUERS-P3 L1PBa1 LTR10B LTR10B1 LTR14C LTR19A LTR36 LTR51 LTR54BLTR56 LTR6B LTR9 LTR9B MER11A MER11D MER34B-int MER34B MER50 MER50BMER57A-int MER6 MER63A MER67A MER91C MLT1A MLT1A0 MLT1E MLT1E2 MLT2B3MSR1 MSTC SST1 THE1B-int THE1B THE1C U1

The 137 categories from Table 12 minus the 48 common variables fromTable 13 result in a list of 89 different variables that are goodclassifiers among tumor and margin comparison experiments but not fortumor-margin-normal comparison experiments. The list of 89 differentvariables is as follows: AluSg/x, AluYa5, AluYa8, tRNA, Charlie 10,ERVK, FLAM_A, HAL1, HERV16, HERV351, HERVL-A1, HERVL40, HSMAR1, L1M3d,L1M4b, L1MA10, L1MA5, L1MA5A, L1MA9, L1MB1, L1MB4, L1MC1, L1MC2, L1MC3,L1MCb, L1MD, L1MD1, L1ME2, L1P1, L1P2, L1P3, L1P4, L1P5, L1PA13, L1PA15,L1PA2, L1PA3, L1PA6, L1PA7, L1PB2, L3b, LTR12, LTR12D, LTR16A, LTR16B,LTR18B, LTR1D, LTR22C, LTR23, LTR24C, LTR26, LTR26B, LTR27, LTR2B,LTR5_Hs, LTR54, LTR67, MER102b, MER106B, MER110A, MER119, MER21-int,MER21A, MER31B, MER34, MER44B, MER46B, MER50-int, MER57A, MER63D,MER65D, MER69B, MER77, MER81, MER90a, MER91A, MER93B, MER94, MIR3, MIRb,MLT1B, MLT1E1, MLT1J2, MLT1L, MSTA-int, PRIMA4-int, Tigger1, Tigger7,Tip100.

The 138 categories from Table 1 minus the 48 common variables in Table13 result in a list of 90 different variables that are good classifiersamong tumor-margin-normal comparison experiments but not fortumor-margin comparisons. The list of 90 different variables is asfollows: 7SK, centr, SVA, Charlie5, Cheshire, ERVL-B4, GSAT, GSATII,Harlequin, HERVFH21, HERVK22, HERVK9, HERVP71A, HUERS-P1, L1M3f, L1MA1,L1MA7, L1PA10, L1PA12, L1PA15-16, L1PB1, L1PB4, LTR14, LTR14B, LTR17,LTR1B, LTR2, LTR22, LTR28, LTR29, LTR30, LTR33A, LTR45B, LTR45C, LTR46,LTR47A, LTR48, LTR48B, LTR5, LTR52, LTR5A, LTR65, LTR66, LTR6A, LTR7,LTR7B, LTR7Y, LTR8, LTR8A, MER105, MER115, MER11B, MER11C, MER34C,MER41E, MER44C, MER44D, MER4A1, MER4D, MER4D1, MER51A, MER51B, MER66C,MER67D, MER6A, MER70A, MER92B, MLT1A1, MLT1D-int, MLT1F, MLT1F1, MLT1G1,MLT2A2, MLT2B1, MLT2B2, MLT2B4, MSTA, MSTB-int, MSTB, MSTB1, MSTD,PABL_A, PABL_B, SVA_A, SVA_B, SVA_C, SVA_D, SVA_E, SVA_F, THE1D.

Table 14 reports the repetitive element families present in a 600-basewindow centered on each microarray probe. This is an example of neighborrepeat analysis. The presence of repetitive DNA sequences belonging todifferent families of repetitive DNA sequences in the same, for example,status biomarker or repetitive DNA sequence locus can facilitate some ofthe forms of the disclosed methods. For example, the differentrepetitive DNA sequences can be used to define a PCR amplicon by, forexample, using primers specific for two of the different repetitive DNAsequences.

TABLE 14 List of neighboring repeats, and their frequencies, that occurin the neighborhood of the probes in the Top 138 categories. ProbeFrequency of other repeats in 2 × 300 window around the Category probeLTR54B AluY - [41.51%], AluSx - [16.98%], AluSp - [11.32%], AluJb -[9.43%], AluSq - [7.55%], MER57A-int - [5.66%], MIR - [5.66%], LTR54 -[5.66%] MER67D AluY - [24.49%], AluSp - [10.20%], AluSx - [10.20%],MER67C - [8.16%], AluSc - [6.12%], L1MC3 - [6.12%] MER11B AluY -[9.76%], L2 - [7.32%] MER6 AluY - [28.17%], AluSx - [14.49%], AluSg -[6.67%], AluSq - [6.07%], L2 - [5.56%], AluSc - [5.21%] ERVL AluY -[30.40%], AluSx - [13.05%], LTR33 - [7.37%], LTR16C - [7.20%], AluSg -[6.02%], L2 - [5.43%], AluSc - [5.03%] U1 AluSx - [27.87%], AluY -[16.39%], AluSg - [9.84%], AluSp - [9.84%] MER34B AluY - [43.97%],AluSx - [22.41%], AluSq - [7.76%], AluSp - [7.76%], MIRb - [6.90%],AluSg - [6.03%] MER66C AluY - [29.63%], AluSx - [20.37%], AluSq -[9.26%], AluSc - [7.41%], AluSp - [5.56%] HUERS-P3 AluY - [43.62%],LTR9 - [17.02%], LTR9B - [14.89%], AluSg - [8.51%], AluSp - [6.38%]LTR56 AluY - [32.53%], AluSx - [22.89%], AluSq - [10.84%], AluSg -[7.23%], AluSp - [7.23%] MLT1G1 AluY - [29.55%], AluSx - [14.17%], L2 -[8.50%], AluSg - [6.48%], AluSc - [5.67%] THE1B-int THE1B - [43.48%],AluY - [28.26%], AluYa5 - [10.87%], LTR12C - [6.52%] HERV9 LTR12C -[22.97%], LTR12 - [10.14%], LTR12_- [8.78%], LTR12D - [8.11%], AluY -[6.76%] MER4D AluY - [31.58%], AluSx - [15.79%], AluSq - [7.29%],AluSg - [6.48%], MER49 - [5.26%], AluSc - [5.26%] LTR14C AluY -[20.00%], HERVK14C - [16.67%], AluSx - [10.00%], AluJo - [6.67%],LTR12C - [6.67%], Tigger1 - [6.67%] MLT2D AluY - [32.18%], AluSx -[9.77%], L2 - [6.90%], AluSp - [6.32%], AluSg - [5.75%], AluSc -[5.17%], AluSq - [5.17%] HERVFH21 AluY - [16.67%], LTR21A - [10.00%],LTR21B - [8.33%] THE1B AluY - [28.51%], AluSx - [8.34%], L2 - [6.95%]LTR6B HERVS71 - [29.55%], AluSx - [6.82%], MIR - [6.82%] MLT1A1 AluY -[32.71%], AluSx - [12.77%], AluSc - [7.48%], AluSp - [7.17%], AluSg -[6.54%], L2 - [5.61%] LTR46 AluSx - [17.95%], AluY - [15.38%], AluSg -[7.69%], L2 - [7.69%], AluJb - [5.13%] centr SST1 - [29.21%], GSATII -[12.70%], ALR/Alpha - [9.21%] Charlie5 AluY - [29.12%], AluSx -[21.07%], L2 - [8.43%], AluSg - [7.28%], AluSq - [6.90%], AluJo -[5.75%], AluSp - [5.75%], AluJb - [5.36%] MLT1D-int MLT1D - [36.84%],AluY - [31.58%], AluSx - [13.16%], AluSc - [10.53%], AluSp - [7.89%],AluSg - [5.26%], AluJb - [5.26%], AluYa5 - [5.26%] MLT2B3 AluY -[37.88%], AluSx - [8.33%], AluSg - [7.58%], MIRb - [7.58%], L2 - [6.82%]MER50B AluY - [30.39%], AluSx - [15.69%], AluSc - [8.82%] HERVK11MER11C - [12.82%], AluY - [10.26%], MLT1D - [5.13%], MER11D - [5.13%],MER11A - [5.13%] MER70A AluY - [28.21%], AluSx - [17.95%], L2 - [7.69%],MLT1A - [5.13%], MIRb - [5.13%], Charlie4a - [5.13%], MSTB - [5.13%],MER70B - [5.13%] Charlie3 AluSx - [17.54%], AluY - [17.54%], AluSg -[8.77%], MIR - [8.77%], MIRb - [5.26%] PABL_B AluY - [19.44%], AluSx -[13.89%], AluSg - [5.56%], AluSq - [5.56%], AluSp - [5.56%], L2 -[5.56%] MER50 AluY - [25.74%], AluSx - [12.75%], AluSg - [7.11%],AluSc - [6.13%] MSR1 AluSx - [7.63%] LTR2 AluY - [18.33%], AluSx -[11.26%], AluSg - [5.95%], Harlequin - [5.30%] LTR10B AluSg - [18.60%],AluY - [18.60%], AluS - [11.63%], AluSp - [9.30%], AluSc - [6.98%] MLT1AAluY - [32.36%], AluSx - [12.68%], L2 - [6.23%], AluSg - [5.89%],AluSc - [5.27%], AluSp - [5.16%], AluSq - [5.10%] HERVK22 LTR22C -[18.07%], LTR22A - [8.43%], AluY - [8.43%], LTR22B - [6.02%] HERVLAluY - [23.11%], AluSq - [6.72%], AluSx - [6.72%], AluSg - [6.30%],LTR18A - [5.04%] LTR33A AluY - [25.86%], L2 - [10.92%], AluSx - [10.92%]LTR10B1 AluSg - [22.86%], AluY - [17.14%], AluS - [14.29%], AluSp -[11.43%], AluSc - [5.71%], MER93b - [5.71%] MSTB-int AluY - [38.24%],MSTB - [35.29%], AluSc - [11.76%], AluSq - [8.82%], AluSx - [8.82%],AluYa5 - [8.82%] Cheshire AluY - [33.33%], AluSx - [31.82%], AluSg -[15.15%], AluSp - [6.06%], AluJb - [6.06%] LTR17 HERV17 - [12.24%] LTR51AluY - [44.12%], AluSx - [23.53%], AluSg - [5.88%], AluSc - [5.88%],AluSp - [5.88%], AluJb - [5.88%], L2 - [5.88%] MSTA AluY - [36.17%],AluSx - [10.73%], AluSg - [5.53%], L2 - [5.53%] MER11A AluY - [13.95%],AluSg - [6.98%] MER51B AluY - [25.56%], AluSx - [23.33%], AluSg -[8.89%], AluSq - [6.67%], AluSp - [6.67%], AluSc - [5.56%] MLT2B2 AluY -[30.77%], AluSx - [12.09%], AluSc - [7.69%], L2 - [7.69%] SVA AluSx -[7.14%] L1PA12 AluY - [28.68%], AluSp - [8.82%], AluSx - [8.09%],AluSg - [5.15%] MSTC AluY - [41.23%], AluSx - [15.64%], AluSg - [7.58%],AluSq - [7.58%], AluSc - [5.69%], L2 - [5.69%] ERVL-B4 AluY - [32.33%],AluSg - [8.27%], AluSx - [8.27%], AluSq - [7.52%] LTR9B AluY - [23.70%],AluSx - [8.15%], AluSp - [6.67%], HUERS- P3b - [5.93%] HERVK14 LTR14B -[26.56%], AluY - [18.75%], LTR14A - [10.94%], LTR14C - [7.81%], MER41C -[6.25%] LTR14B HERVK14 - [28.81%], AluY - [10.17%], AluSx - [6.78%],MIRb - [5.08%] HUERS-P2 AluY - [31.25%], LTR1 - [21.88%], LTR1C -[9.38%], AluSg - [6.25%], LTR12C - [6.25%], AluSc - [6.25%] LTR29 AluY -[38.89%], AluSx - [20.37%], AluSg - [11.11%], AluSp - [11.11%], LTR49 -[9.26%], AluSc - [5.56%], AluJo - [5.56%], MER39 - [5.56%], FLAM_C -[5.56%] LTR6A L2 - [10.96%], HERVS71 - [9.59%], AluY - [6.85%], AluSq -[5.48%], AluJb - [5.48%], AluSx - [5.48%] MSTB1 AluY - [37.05%], AluSx -[12.05%], L2 - [7.14%], AluSg - [6.70%], AluSp - [6.70%], AluSc -[6.25%], AluSq - [5.36%] MSTD AluY - [36.16%], AluSx - [14.25%], AluSg -[10.14%], L2 - [7.67%], AluSc - [6.03%], AluSq - [5.75%] LTR48B AluY -[33.93%], AluSx - [14.29%], MER39 - [12.50%], AluSp - [8.93%], AluSg -[7.14%], AluSq - [7.14%], AluJb - [5.36%], AluYa5 - [5.36%], MER34 -[5.36%] LTR52 AluY - [42.03%], AluSx - [10.14%], AluSg - [7.25%],AluSc - [7.25%], AluSp - [7.25%], AluSq - [5.80%] LTR8 AluY - [28.19%],AluSx - [17.49%], AluSg - [7.20%], AluSq - [6.58%], AluSp - [5.97%]MER105 AluY - [16.22%], AluSg - [13.51%], L2 - [13.51%], AluSx -[10.81%], AluSq - [8.11%], MER5A - [8.11%], AluSp - [5.41%], AluSg/x -[5.41%], MIR - [5.41%], L1PA3 - [5.41%] LTR8A AluY - [27.27%], AluSx -[18.83%], AluSq - [6.49%], AluSg - [5.84%] MER67A AluY - [20.51%],AluSc - [12.82%], AluSq - [12.82%], AluSx - [10.26%], MER67B - [10.26%],AluJo - [7.69%], AluSg - [5.13%], LTR12C - [5.13%], L2 - [5.13%]HUERS-P1 AluY - [33.33%], AluSx - [19.05%], AluSp - [16.67%], LTR8 -[16.67%], LTR8A - [7.14%], AluSc - [7.14%] MER92B AluY - [31.94%],AluSx - [18.06%], AluSc - [9.72%], AluSp - [6.94%], AluSg - [5.56%],AluSq - [5.56%] LTR22 HERVK22 - [32.95%], AluY - [17.05%], L2 - [5.68%]LTR7B HERVH - [28.47%], AluY - [13.87%], AluSx - [7.30%], L2 - [5.84%]L1PB1 AluY - [27.26%], AluSx - [8.12%], AluSg - [5.82%] MER51A AluY -[28.85%], AluSx - [12.50%], AluSg - [8.65%], AluSq - [6.73%], L2 -[6.73%], AluSp - [5.77%] L1PA15-16 AluY - [45.31%], AluSx - [10.94%]LTR36 AluY - [42.00%], AluSx - [18.00%], AluSq - [10.00%] LTR28 AluY -[23.33%], AluSx - [6.67%], L1MA9 - [6.67%], LTR27B - [6.67%] PABL_AAluY - [25.81%], AluSx - [12.90%], AluSg - [8.06%], AluSc - [8.06%],AluSq - [8.06%] LTR45B AluSx - [20.59%], AluY - [14.71%], AluSg -[11.76%], LTR72B - [8.82%], AluSq - [5.88%], AluSp - [5.88%], MER5B -[5.88%], L2 - [5.88%], MIR - [5.88%] MER4D1 AluY - [35.45%], AluSx -[12.73%], AluSq - [10.00%], AluSg - [6.36%] AcHobo AluY - [27.88%],MER63 - [21.36%], MER94 - [18.56%], MER81 - [17.35%], AluSx - [13.84%],MER63A - [12.14%], BLACKJACK - [10.03%], L2 - [8.63%], MER63D - [6.72%],AluSq - [6.22%], AluSg - [5.82%], MER63C - [5.52%] LTR7Y HERVH -[30.39%], L2 - [7.84%], AluSx - [5.88%], MIRb - [5.88%] HERVL18 LTR18A -[28.57%], AluY - [11.90%] LTR48 AluY - [33.86%], AluSg - [14.17%],AluSx - [14.17%], MER34 - [5.51%], MER39 - [5.51%], AluSc - [5.51%],AluSp - [5.51%] LTR30 HERV30 - [20.93%], AluY - [9.30%], AluSx - [6.98%]MLT1A0 AluY - [31.74%], AluSx - [12.66%], L2 - [6.42%], AluSg - [5.66%],AluSq - [5.27%] HERVK9 MER9 - [46.75%], AluY - [7.79%], MER9B - [6.49%]LTR1B AluY - [13.64%], AluSx - [6.36%] LTR45C AluY - [35.29%], AluSx -[23.53%], AluSq - [8.82%], AluJo - [8.82%], AluSc - [5.88%], AluJb -[5.88%] MSTB AluY - [35.01%], AluSx - [15.19%], L2 - [7.08%], AluSc -[5.79%], AluSg - [5.79%], AluSp - [5.02%] LTR47A AluY - [32.20%],AluSx - [13.56%], AluSc - [8.47%], AluSp - [8.47%], AluSq - [5.08%]MER11D AluY - [16.22%], AluSx - [10.81%], MER58A - [5.41%], HERVK11D -[5.41%] LTR19A AluY - [29.73%], AluSq - [18.92%], AluSx - [13.51%],AluSg - [5.41%], SVA_D - [5.41%], L2 - [5.41%], HERVFH19 - [5.41%],L1M5 - [5.41%] THE1C AluY - [26.65%], AluSx - [12.89%], L2 - [6.59%],AluSg - [5.44%] LTR66 HERVL66 - [22.73%], AluY - [20.45%], AluSc -[9.09%], AluSg - [6.82%] MLT1E2 AluY - [34.31%], AluSx - [11.30%],AluSc - [8.37%], L2 - [6.69%] MER115 AluY - [26.24%], AluSx - [11.35%],AluSp - [5.67%] MER34B-int AluY - [54.84%], AluSx - [22.58%], AluSp -[12.90%], AluSc - [6.45%], AluSq - [6.45%], AluJb - [6.45%], MER34 -[6.45%] LTR65 AluY - [23.53%], AluSx - [14.71%], AluSq - [11.76%],AluSg - [8.82%], L2 - [8.82%], MIR - [8.82%], AluJo - [5.88%] MER34CAluY - [29.21%], AluSx - [11.24%], AluSg - [8.99%], MER57A-int -[8.99%], AluSc - [7.87%], AluSp - [5.62%] MER44D AluY - [30.00%],AluSg - [10.00%], MIRb - [10.00%], AluSq - [6.67%], AluSp - [6.67%],LTR33 - [6.67%] MER57A-int AluY - [40.94%], AluSx - [14.17%], AluSc -[7.09%], AluSq - [7.09%], MER34C - [5.51%] MLT2B1 AluY - [29.59%],AluSx - [14.20%], AluSc - [6.51%], AluSg - [5.33%] L1PA10 AluY -[29.82%], AluSx - [9.36%], AluSc - [5.56%] MER4A1 AluY - [26.85%],AluSx - [10.89%], AluSg - [8.17%], AluSp - [5.84%] MER6A AluY -[24.71%], AluSx - [14.12%], L2 - [9.41%], AluSg - [8.24%], AluJb -[7.06%] MLT1E AluY - [35.75%], AluSx - [11.71%], AluSc - [6.47%], L2 -[5.08%] MER41E AluY - [19.44%], AluSx - [16.67%], AluSg - [13.89%],AluSc - [5.56%], AluSq - [5.56%], AluSp - [5.56%], MIR - [5.56%], L1M4 -[5.56%], L1M5 - [5.56%] MLT2B4 AluY - [27.39%], AluSx - [17.83%],D20S16 - [8.28%], AluSc - [5.73%], AluSq - [5.73%], L2 - [5.10%] 7SKAluY - [20.69%], AluSx - [13.79%], L2 - [6.90%] HERVP71A AluY -[34.21%], LTR71A - [21.05%], LTR71B - [13.16%], LTR18B - [10.53%],AluSx - [5.26%] L1MA7 AluY - [34.46%], AluSx - [12.53%], AluSg - [8.36%]L1PBa1 AluY - [16.67%], LTR12C - [10.42%], AluSc - [6.25%] LTR5 AluY -[24.79%], AluSx - [14.22%], AluSg - [5.29%], AluSp - [5.17%] MER44CAluY - [36.84%], AluSx - [26.32%], AluSg - [5.26%], AluSc - [5.26%],AluSq - [5.26%] GSATII GSATX - [5.48%] THE1D AluY - [31.31%], AluSx -[11.15%], AluSg - [6.85%], L2 - [6.26%], AluSq - [5.48%] L1MA1 AluY -[39.07%], AluSx - [12.55%], L1ME1 - [8.91%], AluSg - [7.69%] LTR7HERVH - [17.75%], AluY - [11.23%], L2 - [5.45%] LTR9 AluY - [19.44%],AluSx - [10.77%], HUERS-P3 - [5.15%] MER63A AluY - [33.86%], L2 -[10.24%], AluSx - [9.45%], AluSq - [6.30%] MER91C AluY - [25.00%], L2 -[9.09%], AluSx - [6.82%], MIRb - [6.82%] LTR5A HERVK - [14.71%], MIRb -[11.76%], AluSx - [5.88%], L2 - [5.88%], MER2 - [5.88%] Harlequin LTR2 -[28.68%], LTR2B - [13.18%], AluY - [11.63%] L1PB4 AluY - [35.87%],AluSx - [14.59%], AluSc - [5.78%], AluSq - [5.78%], AluSg - [5.47%]MLT1F1 AluY - [34.31%], AluSx - [21.57%], AluSc - [7.35%], AluSg -[6.37%] L1M3f AluY - [42.86%], AluSx - [9.09%], AluSg - [5.19%], AluSq -[5.19%], AluJo - [5.19%] MLT1F AluY - [31.82%], AluSx - [17.63%],AluSg - [7.58%], L2 - [7.02%], AluSc - [5.79%], AluSp - [5.23%] MLT2A2AluY - [24.26%], AluSx - [8.09%], AluSg - [6.62%], L2 - [5.15%],HERVL-A2 - [5.15%] LTR14 HERVK14 - [18.90%], AluY - [12.60%], AluSx -[7.87%] MER11C AluY - [6.52%], L2 - [5.07%]

A very interesting feature of this analysis is the presence of LTR2 andLTR2B repetitive elements in the vicinity of Harlequin repeats, whichare a special type of LTR repeat. A report in the journal “Oncogene”described an unusual set of human genes known as HOST genes, whichcontain sequences comprising a mixture of Harlequin repetitive elementsjoined to LTR2 repetitive elements (Rangel et al., 2003). HOST genes areoverexpressed in ovarian cancer (Rangel et al., 2003). The presence ofthe Harlequin class of repeats in the list of the best classifier probesfound by the Support Vector Machine analysis indicates the existence ofa large number of genomic loci with a structure similar to that of theovarian cancer HOST genes. These unusual loci suffer major changes inDNA methylation status in cancers of the head and neck, as revealed byanalysis herein.

Table 16 is a list of 126 repetitive element families that occur asneighbors in a window of 2×300 bases near the Top 138 classifier probes.

TABLE 16 List of 126 repetitive element families that occur as neighborsin a window of 2 × 300 bases near the Top 138 classifier probes. howoften it co- localizes with other repeats, near 35235 # of members ofprobes, members of windows of 2 × 300 Repeat the 138 categoriespercentage bases considered AluY 9288 26.36% 35235 AluSx 4062 11.53%35235 MLT1A0 1932 5.48% 35235 AluSg 1668 4.73% 35235 L2 1349 3.83% 35235AluSc 978 2.78% 35235 MSTA 838 2.38% 35235 AluSq 686 1.95% 35235 THE1B686 1.95% 35235 MLT1A1 584 1.66% 35235 L1PB1 570 1.62% 35235 SVA_D 5271.50% 35235 LTR7 506 1.44% 35235 AluSp 479 1.36% 35235 THE1D 470 1.33%35235 MSTB 464 1.32% 35235 LTR33 454 1.29% 35235 LTR16C 441 1.25% 35235MLT1E2 438 1.24% 35235 ERVL-E 431 1.22% 35235 MSTB1 430 1.22% 35235MER63 426 1.21% 35235 MLT1A 398 1.13% 35235 MLT1F1 376 1.07% 35235MER63A 363 1.03% 35235 L1MA7 355 1.01% 35235 LTR2 337 0.96% 35235 MSTD332 0.94% 35235 LTR8 326 0.93% 35235 THE1C 318 0.90% 35235 L1PB4 3130.89% 35235 L1PA10 300 0.85% 35235 LTR9 298 0.85% 35235 LTR8A 293 0.83%35235 MER50 275 0.78% 35235 LTR9B 274 0.78% 35235 LTR7B 270 0.77% 35235L1MA10 257 0.73% 35235 Charlie5 251 0.71% 35235 MLT1F 248 0.70% 35235LTR17 245 0.70% 35235 HERVH 236 0.67% 35235 MLT1G1 225 0.64% 35235 SVA_A223 0.63% 35235 MLT1F2 208 0.59% 35235 MER4D1 204 0.58% 35235 L1MA1 2010.57% 35235 SVA_B 196 0.56% 35235 LTR7Y 192 0.54% 35235 MER50B 192 0.54%35235 MSTC 191 0.54% 35235 MER94 185 0.53% 35235 SST1 184 0.52% 35235SVA_E 175 0.50% 35235 MER81 173 0.49% 35235 MLT2D 166 0.47% 35235 LTR33A164 0.47% 35235 MLT2B1 162 0.46% 35235 MER4A1 156 0.44% 35235 MLT2B4 1510.43% 35235 LTR56 148 0.42% 35235 Harlequin 148 0.42% 35235 MER68 1460.41% 35235 LTR50 137 0.39% 35235 LTR14B 133 0.38% 35235 MER115 1320.37% 35235 MLT1E 132 0.37% 35235 SVA_F 131 0.37% 35235 MER57A-int 1310.37% 35235 MLT2A2 131 0.37% 35235 MLT2B3 126 0.36% 35235 ERVL-B4 1260.36% 35235 LTR5_Hs 125 0.35% 35235 MER66B 124 0.35% 35235 L1PA12 1220.35% 35235 GSATII 120 0.34% 35235 MSR1 114 0.32% 35235 MLT1E1 107 0.30%35235 LTR54B 106 0.30% 35235 MER11C 105 0.30% 35235 HERVK22 105 0.30%35235 MER4D 104 0.30% 35235 LTR48B 104 0.30% 35235 HERV9 102 0.29% 35235LTR52 100 0.28% 35235 BLACKJACK 100 0.28% 35235 MLT1E3 94 0.27% 35235LTR5B 93 0.26% 35235 SVA_C 93 0.26% 35235 MER51A 91 0.26% 35235 LTR1B 910.26% 35235 LTR2C 90 0.26% 35235 HERVK14 89 0.25% 35235 MLT2B2 87 0.25%35235 MER34B 85 0.24% 35235 THE1B-int 84 0.24% 35235 MER6A 84 0.24%35235 LTR2B 83 0.24% 35235 HUERS-P3 82 0.23% 35235 LTR54 79 0.22% 35235L1M3f 72 0.20% 35235 MER92B 69 0.20% 35235 LTR23 68 0.19% 35235 MER63D67 0.19% 35235 MER34C_(—) 67 0.19% 35235 LTR6A 67 0.19% 35235 HERVL18 660.19% 35235 LTR48 64 0.18% 35235 Cheshire 63 0.18% 35235 LTR14C 63 0.18%35235 L1PA15-16 62 0.18% 35235 MER51B 61 0.17% 35235 MER4A1-int 61 0.17%35235 HERVK9 60 0.17% 35235 MER34B-int 60 0.17% 35235 MSTB2 58 0.16%35235 LTR47A 58 0.16% 35235 MER44C 56 0.16% 35235 LTR22C 56 0.16% 35235MLT1E1A 56 0.16% 35235 MER63C 55 0.16% 35235 7SK 55 0.16% 35235 Charlie353 0.15% 35235 LTR29 52 0.15% 35235 LTR10B1 52 0.15% 35235 MLT1F-int 510.14% 35235

TABLE 17 List of Most Common Neighbor Repetitive DNA Sequence FamiliesAluY AluSx MLT1A0 AluSg L2 AluSc MSTA AluSq THE1B MLT1A1 L1PB1 SVA_DLTR7 AluSp THE1D MSTB LTR33 LTR16C MLT1E2 ERVL-E MSTB1 MER63 MLT1AMLT1F1 MER63A L1MA7 LTR2 MSTD LTR8 THE1C L1PB4 L1PA10 LTR9 LTR8A MER50LTR9B LTR7B L1MA10 Charlie5 MLT1F LTR17 HERVH MLT1G1 SVA_A MLT1F2 MER4D1L1MA1 SVA_B LTR7Y MER50B MSTC MER94 SST1 SVA_E MER81 MLT2D LTR33A MLT2B1MER4A1 MLT2B4 LTR56 Harlequin MER68 LTR50 LTR14B MER115 MLT1E SVA_FMER57A-int MLT2A2 MLT2B3 ERVL-B4 LTR5_Hs MER66B L1PA12 GSATII MSR1MLT1E1 LTR54B MER11C HERVK22 MER4D LTR48B HERV9 LTR52 BLACKJACK MLT1E3LTR5B SVA_C MER51A LTR1B LTR2C HERVK14 MLT2B2 MER34B THE1B-int MER6ALTR2B HUERS-P3 LTR54

TABLE 18 List of 569 Repetitive DNA Sequence Families (StatusBiomarkers) 5S 7SK 7SLRNA AcHobo ALR/Alpha Alu AluJ AluJ/FLAM AluJ/FRAMAluJb AluJo/FLAM AluJo/FRAM AluS AluSc AluSg AluSg/x AluSg1 AluSpAluSp/q AluSq AluSq/x AluY AluYa AluYa5 AluYa5/8 AluYa8 AluYb AluYb9AluYc AluYc3 AluYc5 AluYd AluYd8 AluYg AluYg6 AluYh AluYh9 Arthur1BLACKJACK BSR/Beta centr Charlie1 Charlie10 Charlie1b Charlie2 Charlie2aCharlie3 Charlie4 Charlie4a Charlie5 Charlie7 Charlie8 Charlie9 CheshireCR1 DNA ERV ERV1 ERVK ERVL ERVL-B4 ERVL-E FAM FLAM FLAM_A FordPrefectFRAM FRAM/FAM GSAT GSATII HAL1 HAL1b Harlequin HERV16 HERV17 HERV3HERV35I HERV9 HERVE HERVFH21 HERVH HERVH48 HERVI HERVIP10F HERVIP10FHHERVK HERVK11 HERVK14 HERVK22 HERVK3 HERVK9 HERVL HERVL-A1 HERVL18HERVL40 HERVP71A HERVS71 HSMAR1 HSMAR2 HUERS-P1 HUERS-P2 HUERS-P3 HY1HY3 K. standard. SVA_A K. standard. K. standard. K. standard. K.standard. K. standard. SVA_B SVA_C SVA_D SVA_E SVA_F Kanga1 Kanga2_a L1L1HS L1M L1M1 L1M2 L1M3 L1M3b L1M3c L1M3d L1M3e L1M3f L1M4 L1M4b L1M4cL1M5 L1MA1 L1MA10 L1MA2 L1MA3 L1MA4A L1MA5 L1MA5A L1MA6 L1MA7 L1MA8L1MA9 L1MB1 L1MB2 L1MB3 L1MB4 L1MB5 L1MB7 L1MB8 L1MC1 L1MC2 L1MC3 L1MC4L1MC4_3endX L1MC4a L1MC5 L1MCa L1MCb L1MCc L1MD L1MD1 L1MD2 L1MD3 L1MDaL1ME2 L1ME3 L1ME3A L1ME4a L1MEa L1MEb L1MEd L1MEe L1P L1P1 L1P2 L1P3L1P4 L1P4a L1P5 L1PA10 L1PA11 L1PA12 L1PA13 L1PA14 L1PA15 L1PA15-16L1PA16 L1PA17 L1PA2 L1PA3 L1PA4 L1PA5 L1PA6 L1PA7 L1PA8 L1PA8A L1PBL1PB1 L1PB2 L1PB3 L1PB4 L1PBa L1PBa1 L2 L3 L3b LINE Looper LOR1-intLOR1b LTR LTR1 LTR10B LTR10B1 LTR10C LTR10D LTR10F LTR12 LTR12_(—)LTR12B LTR12C LTR12D LTR12E LTR13 LTR13_(—) LTR13A LTR14 LTR14B LTR14CLTR16A LTR16A1 LTR16B LTR16C LTR16D LTR17 LTR18A LTR18B LTR19A LTR1BLTR1C LTR1D LTR2 LTR22 LTR22C LTR23 LTR24 LTR24C LTR26 LTR26B LTR26ELTR27 LTR27B LTR28 LTR29 LTR2B LTR2C LTR3 LTR30 LTR32 LTR33 LTR33A LTR34LTR35 LTR36 LTR37A LTR37B LTR38 LTR39 LTR3A LTR3B LTR40a LTR40b LTR41LTR43 LTR45 LTR45B LTR45C LTR46 LTR47A LTR48 LTR48B LTR49 LTR49-int LTR5LTR5_Hs LTR50 LTR51 LTR52 LTR53 LTR54 LTR54B LTR56 LTR5A LTR5B LTR62LTR65 LTR66 LTR67 LTR6A LTR6B LTR7 LTR72 LTR75 LTR7B LTR7Y LTR8 LTR8ALTR9 LTR9B MADE1 MADE2 MaLR MARNA MER1_type MER1_type? MER101-intMER102b MER103 MER104 MER105 MER106A MER106B MER110 MER110A MER112MER113 MER115 MER117 MER119 MER11A MER11B MER11C MER11D MER121 MER1AMER1B MER2 MER2_type MER20 MER20B MER21-int MER21A MER21B MER21C MER2BMER3 MER30 MER31-int MER31A MER31B MER33 MER34 MER34B MER34B-int MER34CMER34C_(—) MER39 MER39B MER4-int MER41A MER41B MER41B-int MER41C MER41DMER41E MER44A MER44B MER44C MER44D MER45 MER45A MER45B MER45C MER45RMER46A MER46B MER46C MER48 MER49 MER4A MER4A1 MER4A1_(—) MER4A1-intMER4B MER4B-int MER4C MER4D MER4D0 MER4D1 MER4E MER4E1 MER50 MER50-intMER50B MER51A MER51B MER51B-int MER52A MER52C MER52D MER53 MER54A MER54BMER57A MER57A-int MER57B MER57B-int MER58 MER58A MER58B MER58C MER5AMER5A1 MER5B MER5C MER6 MER61A MER61A-int MER61B MER63 MER63A MER63DMER65-int MER65A MER65A-int MER65C MER65D MER66A MER66B MER66C MER67AMER67B MER67C MER67D MER68 MER69A MER69B MER6A MER70A MER72 MER74AMER74B MER75 MER76 MER77 MER7A MER7C MER8 MER81 MER82 MER83 MER84 MER85MER87 MER89 MER9 MER90 MER90a MER91 MER91A MER91B MER91C MER92B MER93aMER93B MER93b MER94 MER96 MER96B MER97c MIR MIR3 MIRb MIRm MLT-int MLT1AMLT1A0 MLT1A0-int MLT1A1 MLT1B MLT1C MLT1D MLT1D-int MLT1E MLT1E1MLT1E1A MLT1E2 MLT1E3 MLT1F MLT1F-int MLT1F1 MLT1F2 MLT1G1 MLT1G3 MLT1HMLT1H-int MLT1H1 MLT1H2 MLT1I MLT1J MLT1J1 MLT1J2 MLT1K MLT1L MLT2A1MLT2A2 MLT2B1 MLT2B2 MLT2B3 MLT2B4 MLT2C1 MLT2C2 MLT2D MLT2E MLT2F MSR1MSTA MSTA-int MSTB MSTB-int MSTB1 MSTB2 MSTC MSTD MuDR ORSL Other PABL_APABL_B PiggyBac PRIMA4_LTR PRIMA4-int REP522 Ricksha RNA rRNA SatelliteSATR1 SATR2 scRNA SINE snRNA srpRNA SST1 SVA TAR1 Tc2 telo THE1A THE1BTHE1B-int THE1C THE1D Tigger1 Tigger2 Tigger2a Tigger3b Tigger4(Zombi)Tigger5 Tigger5a Tigger5b Tigger6 Tigger6a Tigger7 Tigger8 Tip100 tRNAU1 U13 U2 U6 Zaphod Zaphod2

B. Nucleic Acids

There are a variety of molecules disclosed herein that are nucleic acidbased, including, for example, riboswitches, aptamers, and nucleic acidsthat encode riboswitches and aptamers. The disclosed nucleic acids canbe made up of for example, nucleotides, nucleotide analogs, ornucleotide substitutes. Non-limiting examples of these and othermolecules are discussed herein. It is understood that for example, whena vector is expressed in a cell that the expressed mRNA will typicallybe made up of A, C, G, and U. Likewise, it is understood that if anucleic acid molecule is introduced into a cell or cell environmentthrough for example exogenous delivery, it is advantageous that thenucleic acid molecule be made up of nucleotide analogs that reduce thedegradation of the nucleic acid molecule in the cellular environment.

So long as their relevant function is maintained, riboswitches,aptamers, expression platforms and any other oligonucleotides andnucleic acids can be made up of or include modified nucleotides(nucleotide analogs). Many modified nucleotides are known and can beused in oligonucleotides and nucleic acids. A nucleotide analog is anucleotide which contains some type of modification to either the base,sugar, or phosphate moieties. Modifications to the base moiety wouldinclude natural and synthetic modifications of A, C, G, and T/U as wellas different purine or pyrimidine bases, such as uracil-5-yl,hypoxanthin-9-yl (I), and 2-aminoadenin-9-yl. A modified base includesbut is not limited to 5-methylcytosine (5-me-C), 5-hydroxymethylcytosine, xanthine, hypoxanthine, 2-aminoadenine, 6-methyl and otheralkyl derivatives of adenine and guanine, 2-propyl and other alkylderivatives of adenine and guanine, 2-thiouracil, 2-thiothymine and2-thiocytosine, 5-halouracil and cytosine, 5-propynyl uracil andcytosine, 6-azo uracil, cytosine and thymine, 5-uracil (pseudouracil),4-thiouracil, 8-halo, 8-amino, 8-thiol, 8-thioalkyl, 8-hydroxyl andother 8-substituted adenines and guanines, 5-halo particularly 5-bromo,5-trifluoromethyl and other 5-substituted uracils and cytosines,7-methylguanine and 7-methyladenine, 8-azaguanine and 8-azaadenine,7-deazaguanine and 7-deazaadenine and 3-deazaguanine and 3-deazaadenine.Another modified base contains one or more of the2′-O,4′-C-methylene-β-D-ribofuranosyl nucleosides which are known aslocked nucleic acid (LNA™) monomers (Petersen and Wengel, Trends Biotech21:74-81, 2003). Additional base modifications can be found for examplein U.S. Pat. No. 3,687,808, Englisch et al., Angewandte Chemie,International Edition, 1991, 30, 613, and Sanghvi, Y. S., Chapter 15,Antisense Research and Applications, pages 289-302, Crooke, S. T. andLebleu, B. ed., CRC Press, 1993. Certain nucleotide analogs, such as5-substituted pyrimidines, 6-azapyrimidines and N-2, N-6 and O-6substituted purines, including 2-aminopropyladenine, 5-propynyluraciland 5-propynylcytosine. 5-methylcytosine can increase the stability ofduplex formation. Other modified bases are those that function asuniversal bases. Universal bases include 3-nitropyrrole and5-nitroindole. Universal bases substitute for the normal bases but haveno bias in base pairing. That is, universal bases can base pair with anyother base. Base modifications often can be combined with for example asugar modification, such as 2′-β-methoxyethyl, to achieve uniqueproperties such as increased duplex stability. There are numerous UnitedStates patents such as U.S. Pat. Nos. 4,845,205; 5,130,302; 5,134,066;5,175,273; 5,367,066; 5,432,272; 5,457,187; 5,459,255; 5,484,908;5,502,177; 5,525,711; 5,552,540; 5,587,469; 5,594,121, 5,596,091;5,614,617; and 5,681,941, which detail and describe a range of basemodifications. Each of these patents is herein incorporated by referencein its entirety, and specifically for their description of basemodifications, their synthesis, their use, and their incorporation intooligonucleotides and nucleic acids.

LNA™ monomers are a class of nucleic acid analogues in which the ribosering is “locked” into the ideal conformation for base stacking andbackbone pre-organization and can be used just like a regularnucleotide. The nucleic acid contains a methylene bridge connecting the2′-O and the 4′-C. The “locked” structure increases the stability ofoligonucleotides by means of increasing the melting temperature (Kaur etal. Biochemistry 45:7347-55, 2006). LNA™ can be used for a variety ofmolecular biology techniques. Locked nucleic acids can be used for butare not limited to microarrays, FISH probes, real-time PCR probes, smallRNA research, SNP genotyping, mRNA antisense oligonucleotides,allele-specific PCR, RNAi, DNAzymes, fluorescence polarization probes,gene repair/exon skipping, splice variant detection and comparativegenome hybridization.

Nucleotide analogs can also include modifications of the sugar moiety.Modifications to the sugar moiety would include natural modifications ofthe ribose and deoxyribose as well as synthetic modifications. Sugarmodifications include but are not limited to the following modificationsat the 2′ position: OH; F; O-, S-, or N-alkyl; O-, S-, or N-alkenyl; O-,S- or N-alkynyl; or O-alkyl-O-alkyl, wherein the alkyl, alkenyl andalkynyl can be substituted or unsubstituted C1 to C10, alkyl or C2 toC10 alkenyl and alkynyl. 2′ sugar modifications also include but are notlimited to —O[(CH₂)n O]m CH₃, —O(CH₂)n OCH₃, —O(CH₂)n NH₂, —O(CH₂)n CH₃,—O(CH₂)n —ONH₂, and —O(CH₂)nON[(CH₂)n CH₃)]₂, where n and m are from 1to about 10.

Other modifications at the 2′ position include but are not limited to:C1 to C10 lower alkyl, substituted lower alkyl, alkaryl, aralkyl,O-alkaryl or O-aralkyl, SH, SCH₃, OCN, Cl, Br, CN, CF₃, OCF₃, SOCH₃, SO₂CH₃, ONO₂, NO₂, N₃, NH₂, heterocycloalkyl, heterocycloalkaryl,aminoalkylamino, polyalkylamino, substituted silyl, an RNA cleavinggroup, a reporter group, an intercalator, a group for improving thepharmacokinetic properties of an oligonucleotide, or a group forimproving the pharmacodynamic properties of an oligonucleotide, andother substituents having similar properties. Similar modifications canalso be made at other positions on the sugar, particularly the 3′position of the sugar on the 3′ terminal nucleotide or in 2′-5′ linkedoligonucleotides and the 5′ position of 5′ terminal nucleotide. Modifiedsugars would also include those that contain modifications at thebridging ring oxygen, such as CH₂ and S. Nucleotide sugar analogs canalso have sugar mimetics such as cyclobutyl moieties in place of thepentofuranosyl sugar. There are numerous United States patents thatteach the preparation of such modified sugar structures such as U.S.Pat. Nos. 4,981,957; 5,118,800; 5,319,080; 5,359,044; 5,393,878;5,446,137; 5,466,786; 5,514,785; 5,519,134; 5,567,811; 5,576,427;5,591,722; 5,597,909; 5,610,300; 5,627,053; 5,639,873; 5,646,265;5,658,873; 5,670,633; and 5,700,920, each of which is hereinincorporated by reference in its entirety, and specifically for theirdescription of modified sugar structures, their synthesis, their use,and their incorporation into nucleotides, oligonucleotides and nucleicacids.

Nucleotide analogs can also be modified at the phosphate moiety.Modified phosphate moieties include but are not limited to those thatcan be modified so that the linkage between two nucleotides contains aphosphorothioate, chiral phosphorothioate, phosphorodithioate,phosphotriester, aminoalkylphosphotriester, methyl and other alkylphosphonates including 3′-alkylene phosphonate and chiral phosphonates,phosphinates, phosphoramidates including 3′-amino phosphoramidate andaminoalkylphosphoramidates, thionophosphoramidates,thionoalkylphosphonates, thionoalkylphosphotriesters, andboranophosphates. It is understood that these phosphate or modifiedphosphate linkages between two nucleotides can be through a 3′-5′linkage or a 2′-5′ linkage, and the linkage can contain invertedpolarity such as 3′-5′ to 5′-3′ or 2′-5′ to 5′-2′. Various salts, mixedsalts and free acid forms are also included. Numerous United Statespatents teach how to make and use nucleotides containing modifiedphosphates and include but are not limited to, U.S. Pat. Nos. 3,687,808;4,469,863; 4,476,301; 5,023,243; 5,177,196; 5,188,897; 5,264,423;5,276,019; 5,278,302; 5,286,717; 5,321,131; 5,399,676; 5,405,939;5,453,496; 5,455,233; 5,466,677; 5,476,925; 5,519,126; 5,536,821;5,541,306; 5,550,111; 5,563,253; 5,571,799; 5,587,361; and 5,625,050,each of which is herein incorporated by reference its entirety, andspecifically for their description of modified phosphates, theirsynthesis, their use, and their incorporation into nucleotides,oligonucleotides and nucleic acids.

It is understood that nucleotide analogs need only contain a singlemodification, but can also contain multiple modifications within one ofthe moieties or between different moieties.

Nucleotide substitutes are molecules having similar functionalproperties to nucleotides, but which do not contain a phosphate moiety,such as peptide nucleic acid (PNA). Nucleotide substitutes are moleculesthat will recognize and hybridize to (base pair to) complementarynucleic acids in a Watson-Crick or Hoogsteen manner, but which arelinked together through a moiety other than a phosphate moiety.Nucleotide substitutes are able to conform to a double helix typestructure when interacting with the appropriate target nucleic acid.

Nucleotide substitutes can also include nucleotides or nucleotideanalogs that have had the phosphate moiety and/or sugar moietiesreplaced. Nucleotide substitutes do not contain a standard phosphorusatom. Substitutes for the phosphate can be for example, short chainalkyl or cycloalkyl internucleoside linkages, mixed heteroatom and alkylor cycloalkyl internucleoside linkages, or one or more short chainheteroatomic or heterocyclic internucleoside linkages. These includethose having morpholino linkages (formed in part from the sugar portionof a nucleoside); siloxane backbones; sulfide, sulfoxide and sulfonebackbones; formacetyl and thioformacetyl backbones; methylene formacetyland thioformacetyl backbones; alkene containing backbones; sulfamatebackbones; methyleneimino and methylenehydrazino backbones; sulfonateand sulfonamide backbones; amide backbones; and others having mixed N,O, S and CH2 component parts. Numerous United States patents disclosehow to make and use these types of phosphate replacements and includebut are not limited to U.S. Pat. Nos. 5,034,506; 5,166,315; 5,185,444;5,214,134; 5,216,141; 5,235,033; 5,264,562; 5,264,564; 5,405,938;5,434,257; 5,466,677; 5,470,967; 5,489,677; 5,541,307; 5,561,225;5,596,086; 5,602,240; 5,610,289; 5,602,240; 5,608,046; 5,610,289;5,618,704; 5,623,070; 5,663,312; 5,633,360; 5,677,437; and 5,677,439,each of which is herein incorporated by reference its entirety, andspecifically for their description of phosphate replacements, theirsynthesis, their use, and their incorporation into nucleotides,oligonucleotides and nucleic acids.

It is also understood in a nucleotide substitute that both the sugar andthe phosphate moieties of the nucleotide can be replaced, by for examplean amide type linkage (aminoethylglycine) (PNA). U.S. Pat. Nos.5,539,082; 5,714,331; and 5,719,262 teach how to make and use PNAmolecules, each of which is herein incorporated by reference. (See alsoNielsen et al., Science 254:1497-1500 (1991)).

It is also possible to link other types of molecules (conjugates) tonucleotides or nucleotide analogs to enhance for example, cellularuptake. Conjugates can be chemically linked to the nucleotide ornucleotide analogs. Such conjugates include but are not limited to lipidmoieties such as a cholesterol moiety. (Letsinger et al., Proc. Natl.Acad. Sci. USA, 1989, 86, 6553-6556). There are many varieties of thesetypes of molecules available in the art and available herein.

A Watson-Crick interaction is at least one interaction with theWatson-Crick face of a nucleotide, nucleotide analog, or nucleotidesubstitute. The Watson-Crick face of a nucleotide, nucleotide analog, ornucleotide substitute includes the C2, N1, and C6 positions of a purinebased nucleotide, nucleotide analog, or nucleotide substitute and theC2, N3, C4 positions of a pyrimidine based nucleotide, nucleotideanalog, or nucleotide substitute.

A Hoogsteen interaction is the interaction that takes place on theHoogsteen face of a nucleotide or nucleotide analog, which is exposed inthe major groove of duplex DNA.

The Hoogsteen face includes the N7 position and reactive groups (NH2 orO) at the C6 position of purine nucleotides.

Oligonucleotides and nucleic acids can be comprised of nucleotides andcan be made up of different types of nucleotides or the same type ofnucleotides. For example, one or more of the nucleotides in anoligonucleotide can be ribonucleotides, 2′-O-methyl ribonucleotides, ora mixture of ribonucleotides and 2′-O-methyl ribonucleotides; about 10%to about 50% of the nucleotides can be ribonucleotides, 2′-O-methylribonucleotides, or a mixture of ribonucleotides and 2′-O-methylribonucleotides; about 50% or more of the nucleotides can beribonucleotides, 2′-O-methyl ribonucleotides, or a mixture ofribonucleotides and 2′-O-methyl ribonucleotides; or all of thenucleotides are ribonucleotides, 2′-O-methyl ribonucleotides, or amixture of ribonucleotides and 2′-O-methyl ribonucleotides. Sucholigonucleotides and nucleic acids can be referred to as chimericoligonucleotides and chimeric nucleic acids.

It is understood that as discussed herein the use of the terms homologyand identity mean the same thing as similarity. Thus, for example, ifthe use of the word homology is used between two sequences (non-naturalsequences, for example) it is understood that this is not necessarilyindicating an evolutionary relationship between these two sequences, butrather is looking at the similarity or relatedness between their nucleicacid sequences. Many of the methods for determining homology between twoevolutionarily related molecules are routinely applied to any two ormore nucleic acids or proteins for the purpose of measuring sequencesimilarity regardless of whether they are evolutionarily related or not.

In general, it is understood that one way to define any known variantsand derivatives or those that might arise, of the disclosedriboswitches, aptamers, expression platforms, genes and proteins herein,is through defining the variants and derivatives in terms of homology tospecific known sequences. This identity of particular sequencesdisclosed herein is also discussed elsewhere herein. In general,variants of sequences herein disclosed typically have at least, about70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87,88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent homology to astated sequence or a native sequence. Those of skill in the art readilyunderstand how to determine the homology of two proteins or nucleicacids, such as genes. For example, the homology can be calculated afteraligning the two sequences so that the homology is at its highest level.

Another way of calculating homology can be performed by publishedalgorithms. Optimal alignment of sequences for comparison can beconducted by the local homology algorithm of Smith and Waterman Adv.Appl. Math. 2: 482 (1981), by the homology alignment algorithm ofNeedleman and Wunsch, J. MoL Biol. 48: 443 (1970), by the search forsimilarity method of Pearson and Lipman, Proc. Natl. Acad. Sci. U.S.A.85: 2444 (1988), by computerized implementations of these algorithms(GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics SoftwarePackage, Genetics Computer Group, 575 Science Dr., Madison, Wis.), or byinspection.

The same types of homology can be obtained for nucleic acids by forexample the algorithms disclosed in Zuker, M. Science 244:48-52, 1989,Jaeger et al. Proc. Natl. Acad. Sci. USA 86:7706-7710, 1989, Jaeger etal. Methods Enzymol. 183:281-306, 1989 which are herein incorporated byreference for at least material related to nucleic acid alignment. It isunderstood that any of the methods typically can be used and that incertain instances the results of these various methods can differ, butthe skilled artisan understands if identity is found with at least oneof these methods, the sequences would be said to have the statedidentity.

For example, as used herein, a sequence recited as having a particularpercent homology to another sequence refers to sequences that have therecited homology as calculated by any one or more of the calculationmethods described above. For example, a first sequence has 80 percenthomology, as defined herein, to a second sequence if the first sequenceis calculated to have 80 percent homology to the second sequence usingthe Zuker calculation method even if the first sequence does not have 80percent homology to the second sequence as calculated by any of theother calculation methods. As another example, a first sequence has 80percent homology, as defined herein, to a second sequence if the firstsequence is calculated to have 80 percent homology to the secondsequence using both the Zuker calculation method and the Pearson andLipman calculation method even if the first sequence does not have 80percent homology to the second sequence as calculated by the Smith andWaterman calculation method, the Needleman and Wunsch calculationmethod, the Jaeger calculation methods, or any of the other calculationmethods. As yet another example, a first sequence has 80 percenthomology, as defined herein, to a second sequence if the first sequenceis calculated to have 80 percent homology to the second sequence usingeach of calculation methods (although, in practice, the differentcalculation methods will often result in different calculated homologypercentages).

The term hybridization typically means a sequence driven interactionbetween at least two nucleic acid molecules, such as a primer or a probeand a riboswitch or a gene. Sequence driven interaction means aninteraction that occurs between two nucleotides or nucleotide analogs ornucleotide derivatives in a nucleotide specific manner. For example, Ginteracting with C and A interacting with T are sequence driveninteractions. Typically sequence driven interactions occur on theWatson-Crick face or Hoogsteen face of the nucleotide. The hybridizationof two nucleic acids is affected by a number of conditions andparameters known to those of skill in the art. For example, the saltconcentrations, pH, and temperature of the reaction all affect whethertwo nucleic acid molecules will hybridize.

Parameters for selective hybridization between two nucleic acidmolecules are well known to those of skill in the art. For example, insome embodiments selective hybridization conditions can be defined asstringent hybridization conditions. For example, stringency ofhybridization is controlled by both temperature and salt concentrationof either or both of the hybridization and washing steps. For example,the conditions of hybridization to achieve selective hybridization caninvolve hybridization in high ionic strength solution (6×SSC or 6×SSPE)at a temperature that is about 12-25° C. below the Tm (the meltingtemperature at which half of the molecules dissociate from theirhybridization partners) followed by washing at a combination oftemperature and salt concentration chosen so that the washingtemperature is about 5° C. to 20° C. below the Tm. The temperature andsalt conditions are readily determined empirically in preliminaryexperiments in which samples of reference DNA immobilized on filters arehybridized to a labeled nucleic acid of interest and then washed underconditions of different stringencies. Hybridization temperatures aretypically higher for DNA-RNA and RNA-RNA hybridizations. The conditionscan be used as described above to achieve stringency, or as is known inthe art (Sambrook et al., Molecular Cloning: A Laboratory Manual, 2ndEd., Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., 1989;Kunkel et al. Methods Enzymol. 1987:154:367, 1987 which is hereinincorporated by reference for material at least related to hybridizationof nucleic acids). A preferable stringent hybridization condition for aDNA:DNA hybridization can be at about 68° C. (in aqueous solution) in6×SSC or 6×SSPE followed by washing at 68° C. Stringency ofhybridization and washing, if desired, can be reduced accordingly as thedegree of complementarity desired is decreased, and further, dependingupon the G-C or A-T richness of any area wherein variability is searchedfor. Likewise, stringency of hybridization and washing, if desired, canbe increased accordingly as homology desired is increased, and further,depending upon the G-C or A-T richness of any area wherein high homologyis desired, all as known in the art.

Another way to define selective hybridization is by looking at theamount (percentage) of one of the nucleic acids bound to the othernucleic acid. For example, in some embodiments selective hybridizationconditions would be when at least about, 60, 65, 70, 71, 72, 73, 74, 75,76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93,94, 95, 96, 97, 98, 99, 100 percent of the limiting nucleic acid isbound to the non-limiting nucleic acid. Typically, the non-limitingnucleic acid is in for example, 10 or 100 or 1000 fold excess. This typeof assay can be performed at under conditions where both the limitingand non-limiting nucleic acids are for example, 10 fold or 100 fold or1000 fold below their k_(d), or where only one of the nucleic acidmolecules is 10 fold or 100 fold or 1000 fold or where one or bothnucleic acid molecules are above their k_(d).

Another way to define selective hybridization is by looking at thepercentage of nucleic acid that gets enzymatically manipulated underconditions where hybridization is required to promote the desiredenzymatic manipulation. For example, in some embodiments selectivehybridization conditions would be when at least about, 60, 65, 70, 71,72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89,90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100 percent of the nucleic acidis enzymatically manipulated under conditions which promote theenzymatic manipulation, for example if the enzymatic manipulation is DNAextension, then selective hybridization conditions would be when atleast about 60, 65, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82,83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100percent of the nucleic acid molecules are extended. Preferred conditionsalso include those suggested by the manufacturer or indicated in the artas being appropriate for the enzyme performing the manipulation.

Just as with homology, it is understood that there are a variety ofmethods herein disclosed for determining the level of hybridizationbetween two nucleic acid molecules. It is understood that these methodsand conditions can provide different percentages of hybridizationbetween two nucleic acid molecules, but unless otherwise indicatedmeeting the parameters of any of the methods would be sufficient. Forexample if 80% hybridization was required and as long as hybridizationoccurs within the required parameters in any one of these methods it isconsidered disclosed herein.

It is understood that those of skill in the art understand that if acomposition or method meets any one of these criteria for determininghybridization either collectively or singly it is a composition ormethod that is disclosed herein.

1. Probes and Primers

Disclosed are compositions including primers and probes, which arecapable of interacting with the disclosed nucleic acids such as statusbiomarkers, DNA fragments, repetitive DNA sequences, unique sequences,PCR amplicons, and probe binding sequences. In certain embodiments theprimers are used to support DNA amplification reactions. Typically theprimers will be capable of being extended in a sequence specific manner.Extension of a primer in a sequence specific manner includes any methodswherein the sequence and/or composition of the nucleic acid molecule towhich the primer is hybridized or otherwise associated directs orinfluences the composition or sequence of the product produced by theextension of the primer. Extension of the primer in a sequence specificmanner therefore includes, but is not limited to, PCR, DNA sequencing,DNA extension, DNA polymerization, RNA transcription, or reversetranscription. Techniques and conditions that amplify the primer in asequence specific manner are preferred. In certain embodiments theprimers are used for the DNA amplification reactions, such as PCR ordirect sequencing. It is understood that in certain embodiments theprimers can also be extended using non-enzymatic techniques, where forexample, the nucleotides or oligonucleotides used to extend the primerare modified such that they will chemically react to extend the primerin a sequence specific manner. Typically the disclosed primers hybridizewith the disclosed nucleic acids or region of the nucleic acids or theyhybridize with the complement of the nucleic acids or complement of aregion of the nucleic acids.

Probe for biomarkers can be designed in any suitable manner. Examples ofmethods and techniques for designing probes are described herein, butany other methods and techniques can be used. Useful probes can bespecific for particular biomarkers, loci, families of biomarkers,families of loci, etc. Sequence analysis of biomarker and loci sequences(such as nucleic acid regions containing CpG islands and CpG islets) canbe used to identify specific and/or selective probes. Particularlyuseful probes can be complementary to unique sequences in biomarkers andloci of interest or to characteristic or consensus sequences inbiomarker and locus families.

The size of the primers or probes for interaction with the nucleic acidsin certain embodiments can be any size that supports the desiredenzymatic manipulation of the primer, such as DNA amplification or thesimple hybridization of the probe or primer. A typical primer or probewould be at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19,20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37,38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55,56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73,74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91,92, 93, 94, 95, 96, 97, 98, 99, 100, 125, 150, 175, 200, 225, 250, 275,300, 325, 350, 375, 400, 425, 450, 475, 500, 550, 600, 650, 700, 750,800, 850, 900, 950, 1000, 1250, 1500, 1750, 2000, 2250, 2500, 2750,3000, 3500, or 4000 nucleotides long.

In other embodiments a primer or probe can be less than or equal to 6,7, 8, 9, 10, 11, 12 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25,26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43,44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61,62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79,80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97,98, 99, 100, 125, 150, 175, 200, 225, 250, 275, 300, 325, 350, 375, 400,425, 450, 475, 500, 550, 600, 650, 700, 750, 800, 850, 900, 950, 1000,1250, 1500, 1750, 2000, 2250, 2500, 2750, 3000, 3500, or 4000nucleotides long.

The disclosed methods involve the use of probes and primers. Forexample, probes for status biomarkers are used to capture, detect,measure, and/or assess status biomarkers. These and other probes can bedesigned and made using any suitable techniques. Many such techniquesare known in the art. The examples and other description herein provideexamples of the design of probes and of features useful to the probes tobe used in the disclosed methods. The disclosed probes can be used, forexample, to detect the level of the status biomarkers by using, forexample, an array of probes specific for the status biomarkers. In someforms, the array of probes can be, for example, a microarray.

Useful forms of the disclosed probes can be complementary to, and/orspecific for, any sequence in a status biomarker. Such complementarysequences in status biomarkers can be referred to as probe bindingsites. Particularly useful target sequences for probes are uniquesequences and repetitive DNA sequences. Useful probes for uniquesequences can have a sequence of sufficient length and having anucleotide sequence distinctive enough to hybridize uniquely in thegenome at the unique sequence. For example, nucleic acid sequences of orat least 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90,95, or 100 nucleotides in length can be used as probes for uniquesequences. Unique sequences can be identified by, for example, analysisof a genome sequence or by analysis of probe hybridization. Probes forrepetitive DNA sequences and other targets can have any useful length.For example, nucleic acid sequences of or at least 10, 15, 20, 25, 30,35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, or 100 nucleotidesin length can be used as probes.

Probes can be specific for probe binding sites in status biomarkers. Insome forms, the one or more of the status biomarkers can comprise aprobe binding site, wherein the probe binding site of the one or more ofthe status biomarkers is specific for a probe. Probe binding sites canbe, for example, all or a portion of a unique sequence in the statusbiomarker. In some forms, one or more of the probes can be specific fora repetitive DNA sequence locus, wherein the repetitive DNA sequencelocus comprises one or more repetitive DNA sequences, whereinindependently for each of the one or more of the probes one or more ofthe repetitive DNA sequences belongs to a family of repetitive DNAsequences listed in, for example, Table 1, Table 12, or Table 13. Insome forms, each probe can be specific for a repetitive DNA sequencelocus, wherein independently for each probe one or more of therepetitive DNA sequences belongs to a family of repetitive DNA sequencessuch as the repetitive DNA sequence families listed in, for example,Table 1, Table 12, or Table 13.

In some forms, one or more of the probes can be specific for arepetitive DNA sequence locus, wherein the repetitive DNA sequence locuscomprises one or more repetitive DNA sequences, wherein for one or moreof the probes one or more of the repetitive DNA sequences is aninterspersed repeat element. In some forms, each probe can be specificfor a repetitive DNA sequence locus, wherein for each probe one or moreof the repetitive DNA sequences is an interspersed repeat element.

Primers can be used in the disclosed methods to replicate and/or amplifynucleic acids. For example, primers for PCR can be used to amplifygenomic sequences and sequences of status biomarkers. Primers can alsobe used for other replication and replication techniques, such amultiple displacement amplification and replication-based nucleic acidsequencing techniques. Many such techniques are known and principles andtechniques for design of primers for use in such techniques are knownand can be used for the disclosed primers and methods.

In some forms of the disclosed methods, part or all of a statusbiomarker can be replicated and/or amplified as a PCR amplicon. In someforms, one or more of the status biomarkers can comprise a PCR amplicon.A PCR amplicon is a region of nucleic acid including and between thebinding sites of PCR primers. PCR amplicons can be said to be defined bythe binding sites of the primers and by the primers themselves. In someforms, the PCR amplicon of each of the one or more of the statusbiomarkers can be defined by a first primer specific for a single one ofthe status biomarkers and a second primer. A primer specific for astatus biomarker refers to a primer that can bind to a sequence in, andprime replication of, the status biomarker. A primer specific for arepetitive DNA sequence refers to a primer that can bind to a sequencein, and prime replication of, the repetitive DNA sequence. In someforms, the PCR amplicon of each of the one or more of the statusbiomarkers can be defined by the same first primer specific for a firsttype of repetitive DNA sequence and a second primer, wherein the secondprimer is specific for a second type of repetitive DNA sequence, whereinthe second primer is the same for some and different for some of the oneor more of the status biomarkers. In some forms, the first primer can bespecific for one of the families of repetitive DNA sequences listed inTable 16 or 17, wherein independently for each of the one or more of thestatus biomarkers the second primer is specific for a family ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. A primerspecific for a family of repetitive DNA sequence refers to a primer thatcan bind to a sequence in, and prime replication of, one or morerepetitive DNA sequences in the family of repetitive DNA sequences.

The presence of repetitive DNA sequences belonging to different familiesof repetitive DNA sequences in the same, for example, status biomarkeror repetitive DNA sequence locus can facilitate some of the forms of thedisclosed methods. For example, the different repetitive DNA sequencescan be used to define a PCR amplicon by, for example, using primersspecific for two of the different repetitive DNA sequences.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, amplifying the processed DNA anddetermining the ratio of cytosine to thymidine in the amplified DNA andconverting the ratio to the level of methylated forms of the statusbiomarkers. In some forms, the processed DNA can be amplified via, forexample, PCR amplification of the status biomarkers using primersspecific for the status biomarkers.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, PCR amplification of the statusbiomarkers using primers specific for the status biomarkers. In someforms, the PCR amplification can be quantitative PCR. In some forms, thePCR amplification can be nanoliter-microarray quantitative PCR.

Probes can also be used to capture status biomarkers and sequencesderived from status biomarkers. Such probes can be referred to ascapture probes, status biomarker capture probes, or status biomarkerprobes. In some forms, treating the DNA sample can be accomplished by,for example, capturing status biomarker DNA fragments. In some forms,the status biomarker DNA fragments can be captured by, for example,binding DNA fragments in the DNA sample to status biomarker probesattached to a support. In some forms, one or more of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences. In some forms, each of the status biomarker probes canspecifically hybridize to one or more repetitive DNA sequences. Suchprobes can be specific for specific repetitive DNA sequences. Suchprobes can also be specific for a group or family of repetitive DNAsequences or a group or family of status biomarkers. For example, one ormore of the status biomarker probes can comprise degenerate sequencerepresenting a consensus sequence for a family of repetitive DNAsequences. In some forms, the family of repetitive DNA sequences can bea family of repetitive DNA sequences such as the repetitive DNA sequencefamilies listed in, for example, Table 1, Table 12, or Table 13. In someforms, the one or more of the status biomarker probes can comprisedifferent degenerate sequences each representing a consensus sequencefor a different one of the families of repetitive DNA sequences such asthe repetitive DNA sequence families listed in, for example, Table 1,Table 12, or Table 13. In some forms, the one or more of the statusbiomarker probes can comprise at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11,12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29,30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47,48, 49, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 105, 110, 115, 120,125, 130, or 135 different degenerate sequences each representing adifferent consensus sequence for a different one of the families ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. The families ofrepetitive DNA sequences can be selected for in any manner, including byselecting the first at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14,15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32,33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50,55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 105, 110, 115, 120, 125, 130,or 135 families in rank order. In some forms, the support can comprise,for example, gel, a bead, a magnetic bead, a plate, a slide, a surface,or a microparticle. In some forms, DNA not captured can be separatedfrom the captured status biomarker DNA fragments. In some forms, thesequencing can be a form of SMRT sequencing.

In some forms, the method can further comprise, after capturing statusbiomarker DNA fragments and prior to sequencing the captured statusbiomarker DNA fragments, releasing the captured status biomarker DNAfragments and recapturing the released status biomarker DNA fragments.In some forms, the status biomarker DNA fragments can be recaptured bybinding DNA fragments in the DNA sample to secondary status biomarkerprobes attached to a support. In some forms, one or more of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein the one or more of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, each of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein each of the status biomarker probes comprisesdegenerate sequence representing a consensus sequence for a family ofrepetitive DNA sequences. In some forms, the family of repetitive DNAsequences can be a family of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 16 andTable 17. In some forms, the family of repetitive DNA sequences can be afamily of repetitive DNA sequences listed in Table 16 or 17. Forexample, the family of repetitive DNA sequences can be the AluY, AluSx,AluSp, AluSg, or AluSc family of repetitive DNA sequences. In someforms, the one or more of the status biomarker probes can comprisedifferent degenerate sequences each representing a consensus sequencefor a different one of the families of repetitive DNA sequences such asthe repetitive DNA sequence families listed in, for example, Table 16and Table 17. In some forms, the one or more of the status biomarkerprobes can comprise different degenerate sequences each representing aconsensus sequence for a different one of the families of repetitive DNAsequences listed in Table 16 or 17, such as AluY, AluSx, AluSp, AluSg,or AluSc.

In some forms, status biomarker probes can be produced by, for example,selecting a subset of repetitive DNA sequence loci from a set ofrepetitive DNA sequence loci, generating a set of status biomarker probesequences, and synthesizing one or more status biomarker probes. In someforms, the method for producing status biomarker probes can furthercomprise selecting one or more additional subsets of repetitive DNAsequence loci each from a different additional set of repetitive DNAsequence loci, generating one or more additional sets of statusbiomarker probe sequences each based on one of the one or moreadditional subsets, and synthesizing one or more additional statusbiomarker probes, wherein each additional status biomarker probe has thesequence of one of the additional status biomarker probe sequences. Insome forms, the repetitive DNA sequence loci in the set of repetitiveDNA sequence loci can belong to a single one of the families ofrepetitive DNA sequence such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13, wherein thesubset of repetitive DNA sequence loci can be selected by identifyingthose repetitive DNA sequence loci that comprise a repetitive DNAsequence belonging to one of the families of repetitive DNA sequencessuch as the repetitive DNA sequence families listed in, for example,Table 16 and Table 17. In some forms, the repetitive DNA sequence lociin each additional set of repetitive DNA sequence loci can independentlybelong to a different single one of the families of repetitive DNAsequence such as the repetitive DNA sequence families listed in, forexample, Table 1, Table 12, or Table 13, wherein the repetitive DNAsequence loci in the set of repetitive DNA sequence loci and in eachadditional set of repetitive DNA sequence loci belong to differentfamilies of repetitive DNA sequence.

In some forms, each status biomarker probe sequence in a set can have alength of, for example, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70,75, 80, 85, 90, 95, or 100 bases or more. In some forms, each statusbiomarker probe represented in the set of status biomarker probesequences can hybridize to, for example, at least 1%, 2%, 3%, 4%, 5%,6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15% of the repetitive DNAsequence loci in the selected subset of repetitive DNA sequence loci. Insome forms, each status biomarker probe can have the sequence of one ofthe generated status biomarker probe sequences.

In some forms, the set of status biomarker probe sequences can include,for example, any range of from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12,13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30,32, 34, 35, 36, 38, 40, 42, 44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80,85, 90, 95, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, or 200 to1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20,21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35, 36, 38, 40, 42, 44,45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 110, 120, 130,140, 150, 160, 170, 180, 190, or 200 status biomarker probe sequences.In some forms, the set of status biomarker probe sequences can comprisefrom 5 to 100 status biomarker probe sequences. In some forms, the setof status biomarker probe sequences can comprise from 10 to 100 statusbiomarker probe sequences. In some forms, one or more of the additionalsets of status biomarker probe sequences each can comprise from 1 to 100status biomarker probe sequences. In some forms, the one or moreadditional sets of status biomarker probe sequences each can comprisefrom 5 to 100 status biomarker probe sequences. In some forms, the oneor more additional sets of status biomarker probe sequences each cancomprise from 10 to 100 status biomarker probe sequences.

C. Solid Supports

The disclosed methods and compositions can use supports. For example,probes and primers can be attached or associated with supports for usein the disclosed methods. Such probe and primer associated supports cantake the form of, for example, arrays and microarrays. Solid supportsare solid-state substrates or supports with which molecules (such asprobes and primers) can be associated. Probes, primers, and othermolecules can be associated with solid supports directly or indirectly.For example, probes can be bound to the surface of a solid support orassociated with capture agents (e.g., oligonucleotides or molecules thatbind a probe) immobilized on solid supports. As another example, probescan be bound to the surface of a solid support or associated witholigonucleotides immobilized on solid supports. An array is a solidsupport to which multiple probes, primers, or other molecules have beenassociated in an array, grid, or other organized pattern.

Solid-state substrates for use in solid supports can include any solidmaterial with which components can be associated, directly orindirectly. This includes materials such as gel, acrylamide, agarose,cellulose, nitrocellulose, glass, gold, polystyrene, polyethylene vinylacetate, polypropylene, polymethacrylate, polyethylene, polyethyleneoxide, polysilicates, polycarbonates, teflon, fluorocarbons, nylon,silicon rubber, polyanhydrides, polyglycolic acid, polylactic acid,polyorthoesters, functionalized silane, polypropylfumerate, collagen,glycosaminoglycans, and polyamino acids. Solid-state substrates can haveany useful form including thin film, membrane, bottles, dishes, plates,slides, fibers, woven fibers, shaped polymers, chromatography matrix,particles, magnetic particles, beads, magnetic beads, microparticles,magnetic microparticles, nanoparticles, magnetic nanoparticles, or acombination. Solid-state substrates and solid supports can be porous ornon-porous. A chip is a rectangular or square small piece of material.Useful forms for solid-state substrates are thin films, beads, or chips.A useful form for a solid-state substrate is a microtiter dish. In someembodiments, a multiwell glass slide can be employed.

An array can include a plurality of probes, other molecules, compoundsor primers immobilized at identified or predefined locations on thesolid support. Each predefined location on the solid support generallyhas one type of component (that is, all the components at that locationare the same). Alternatively, multiple types of components can beimmobilized in the same predefined location on a solid support. Eachlocation will have multiple copies of the given components. The spatialseparation of different components on the solid support allows separatedetection and identification.

Although useful, it is not required that the solid support be a singleunit or structure. A set of probes, other molecules, compounds and/orprimers can be distributed over any number of solid supports. Forexample, at one extreme, each component can be immobilized in a separatereaction tube or container, or on separate beads or microparticles.

Methods for immobilization of oligonucleotides to solid-state substratesare well established. Oligonucleotides, including address probes anddetection probes, can be coupled to substrates using establishedcoupling methods. For example, suitable attachment methods are describedby Pease et al., Proc. Natl. Acad. Sci. USA 91(11):5022-5026 (1994), andKhrapko et al., Mol Biol (Mosk) (USSR) 25:718-730 (1991). A method forimmobilization of 3′-amine oligonucleotides on casein-coated slides isdescribed by Stimpson et al., Proc. Natl. Acad. Sci. USA 92:6379-6383(1995). A useful method of attaching oligonucleotides to solid-statesubstrates is described by Guo et al., Nucleic Acids Res. 22:5456-5465(1994).

Each of the components (for example, probes, primers, or othermolecules) immobilized on the solid support can be located in adifferent predefined region of the solid support. The differentlocations can be different reaction chambers. Each of the differentpredefined regions can be physically separated from each other of thedifferent regions. The distance between the different predefined regionsof the solid support can be either fixed or variable. For example, in anarray, each of the components can be arranged at fixed distances fromeach other, while components associated with beads will not be in afixed spatial relationship. In particular, the use of multiple solidsupport units (for example, multiple beads) will result in variabledistances.

Components can be associated or immobilized on a solid support at anydensity. Components can be immobilized to the solid support at a densityexceeding 400 different components per cubic centimeter. Arrays ofcomponents can have any number of components. For example, an array canhave at least 1,000 different components immobilized on the solidsupport, at least 10,000 different components immobilized on the solidsupport, at least 100,000 different components immobilized on the solidsupport, or at least 1,000,000 different components immobilized on thesolid support.

D. Samples

Any nucleic acid sample can be used with the disclosed methods. Examplesof suitable nucleic acid samples include DNA samples, genomic samples,mRNA samples, cDNA samples, nucleic acid libraries (including cDNA andgenomic libraries), whole cell samples, culture samples, tissue samples,bodily fluids, biopsy samples, or a combination. Numerous other sourcesof nucleic acid samples are known or can be developed and any can beused with the disclosed method. Generally, it is useful to use a genomicsample from cells, tissues, subjects, that are relevant to the statusbeing assessed.

The source, identity, and preparation of many such nucleic acid samplesare known. The nucleic acid sample can be, for example, a nucleic acidsample from one or more cells, tissue, skin, lung, head, neck, prostate,breast, ovary, brain, liver, stomach, intestine, kidney, testicle,cervix, uterus, spleen, bone, throat, esophagus, muscle, or bodilyfluids such as blood, urine, semen, lymphatic fluid, cerebrospinalfluid, or amniotic fluid, or other biological samples, such as tissueculture cells, buccal swabs, mouthwash, stool, tissues slices, andbiopsy aspiration. Types of useful DNA samples include blood samples,urine samples, semen samples, lymphatic fluid samples, cerebrospinalfluid samples, amniotic fluid samples, biopsy samples, needle aspirationbiopsy samples, cancer samples, tumor samples, tissue samples, cellsamples, cell lysate samples, crude cell lysate samples, forensicsamples, infection samples, and/or nosocomial infection samples.

Nucleic acid fragments are segments of larger nucleic molecules. Nucleicacid fragments, as used in the disclosed method, generally refer tonucleic acid molecules that have been cleaved. A nucleic acid samplethat has been incubated with a nucleic acid cleaving reagent is referredto as a digested sample. A nucleic acid sample that has been digestedusing a restriction enzyme is referred to as a digested sample.

E. Kits

The materials described herein as well as other materials can bepackaged together in any suitable combination as a kit useful forperforming, or aiding in the performance of, the disclosed method. It isuseful if the kit components in a given kit are designed and adapted foruse together in the disclosed method. For example disclosed are kits forassessing status of a subject, the kit comprising probes for statusbiomarkers. The kits also can contain status biomarker capture probes,primers for multiple displacement amplification, PCR primers,restriction endonucleases, or a combination.

F. Mixtures

Disclosed are mixtures formed by performing or preparing to perform thedisclosed method. For example, disclosed are mixtures comprising a DNAsample and restriction endonucleases, a DNA sample and primers, a DNAsample and probes, digested, amplified DNA and probes, treated DNA andprobes, etc.

Whenever the method involves mixing or bringing into contactcompositions or components or reagents, performing the method creates anumber of different mixtures. For example, if the method includes 3mixing steps, after each one of these steps a unique mixture is formedif the steps are performed separately. In addition, a mixture is formedat the completion of all of the steps regardless of how the steps wereperformed. The present disclosure contemplates these mixtures, obtainedby the performance of the disclosed methods as well as mixturescontaining any disclosed reagent, composition, or component, forexample, disclosed herein.

G. Systems

Disclosed are systems useful for performing, or aiding in theperformance of, the disclosed method. Systems generally comprisecombinations of articles of manufacture such as structures, machines,devices, and the like, and compositions, compounds, materials, and thelike. Such combinations that are disclosed or that are apparent from thedisclosure are contemplated. For example, disclosed and contemplated aresystems comprising detection apparatus and arrays of probes.

H. Data Structures and Computer Control

Disclosed are data structures used in, generated by, or generated from,the disclosed method. Data structures generally are any form of data,information, and/or objects collected, organized, stored, and/orembodied in a composition or medium. A pattern of methylation statesand/or levels for status biomarkers stored in electronic form, such asin RAM or on a storage disk, is a type of data structure.

The disclosed method, or any part thereof or preparation therefor, canbe controlled, managed, or otherwise assisted by computer control. Suchcomputer control can be accomplished by a computer controlled process ormethod, can use and/or generate data structures, and can use a computerprogram. Such computer control, computer controlled processes, datastructures, and computer programs are contemplated and should beunderstood to be disclosed herein.

Uses

The disclosed methods and compositions are applicable to numerous areasincluding, but not limited to, assessment of status of cells, tissues,and or subjects, such as by assessment of the presence, stage, risk,etc. of a disease or condition. Other uses include assessing agingand/or general health of cells, tissues, and/or subjects. Other uses aredisclosed, apparent from the disclosure, and/or will be understood bythose in the art.

Methods

Disclosed are methods of assessing one or more statuses of a subject.Also disclosed are methods of identifying status biomarkers associatedwith a status of a subject. Also disclosed are methods of producingstatus biomarker capture probes.

A. Method of Using Status Biomarkers

Status biomarkers can be used to assessing one or more statuses of asubject. This can be done by, for example, determining the methylationstate of one or more status biomarkers in the subject, and comparing oneor more of the determined methylation states to one or more referencemethylation states, wherein a difference, lack of a difference, or bothin one or more of the determined methylation states and one or more ofthe reference methylation states indicates one or more statuses of thesubject.

i. Determining Methylation State

The methylation state of status biomarkers can be determined using anysuitable technique or method. A number of techniques for detecting anddetermining the presence and level of methylation of DNA are known. Suchmethods and techniques can be used in the disclosed methods. Generally,methylation can be determined via direct detection of methylatednucleotides or indirectly by altering or separating nucleotides ornucleic acid acids based on the presence or absence of methylation. Insome forms, the methylation state can be determined by, for example,treating a DNA sample of the subject to differentiate methylated andunmethylated nucleotides, and detecting the level of methylated forms ofthe one or more status biomarkers in the treated DNA, detecting thelevel of unmethylated forms of the one or more status biomarkers in thetreated DNA, or both, wherein the level of methylated forms of thestatus biomarkers, the level of unmethylated forms of the statusbiomarkers, or both indicates the methylation state of the statusbiomarkers.

a. Treating DNA Samples

In some forms, treating the DNA sample can be accomplished by, forexample, incubating the DNA sample with one or more restrictionendonucleases and amplifying the incubated DNA, wherein the restrictionendonucleases are methylation-sensitive restriction endonucleases,wherein the level of the status biomarkers in the amplified DNA is lowerwhen the status biomarkers have reduced methylation and the level of thestatus biomarkers in the amplified DNA is higher when the statusbiomarkers have increased methylation, wherein the level of the statusbiomarkers comprise the level of methylated forms of the one or morestatus biomarkers in the treated DNA, the level of unmethylated forms ofthe one or more status biomarkers in the treated DNA, or both. Anexample of such forms of the methods is described in Example 3. Amethylation-sensitive restriction endonuclease is a restrictionendonuclease that cleaves only at unmethylated recognition and/orcleavage sites. Amplification can distinguish methylated andunmethylated status biomarkers via differential cleavage of restrictionendonuclease based on the methylation state of the DNA. For example,cleaving DNA into smaller fragments can reduce the amplification of theDNA. Multiple displacement amplification is useful for this purpose. Themethylation state can then be determined by detecting or assessing thepresence, absence, or level of amplified nucleic acid.

In some forms, the restriction endonucleases can further comprise atleast one methylation-dependent restriction endonuclease. Amethylation-dependent restriction endonuclease is a restrictionendonuclease that cleaves only at methylated recognition and/or cleavagesites. In some forms, the restriction endonucleases can further compriseat least one methylation-independent restriction endonuclease. Amethylation-independent restriction endonuclease is a restrictionendonuclease that cleaves at both methylated and unmethylatedrecognition and/or cleavage sites. In some forms, the restrictionendonucleases can comprise AciI and HhaI. In some forms, the restrictionendonucleases can comprise McrBC. In some forms, incubating the DNAsample with one or more endonucleases can be accomplished by, forexample, incubating different aliquots of the DNA sample with differentrestriction endonucleases. In some forms, amplifying the incubated DNAcan be accomplished by, for example, multiple displacementamplification. An example of such forms of the methods is described inExample 3. Techniques useful for these forms of assessment ofmethylation states are described in U.S. Patent Application PublicationNo. 20060292585.

In some forms, treating the DNA sample can be accomplished by, forexample, processing the DNA sample with sodium bisulfite. An example ofsuch forms of the methods is described in Example 4. Sodium bisulfiteconverts cytosine to uridine but does not convert methylcytosine. Thisallows detection of methylation and methylation levels by detectingcytosine and thymidine. The ratio of cytosine to thymidine can beconverted to the relative methylation level.

In some forms, treating the DNA sample can be accomplished by, forexample, fragmenting the DNA and separating methylated DNA fromunmethylated DNA. An example of such forms of the methods is describedin Example 5. In some forms, the DNA can be fragmented by, for example,nebularization, cleavage with a restriction endonuclease, sonication, ora combination. In some forms, methylated DNA can be separated fromunmethylated DNA by, for example, binding methylated DNA with a specificbinding molecule specific for methyl groups and separating the boundfrom the unbound DNA. In some forms, the specific binding molecule cancomprise, for example, an antibody specific for 5-methyl cytosine,methyl-biding protein MBD1, methyl-biding protein MECP2, or acombination. Numerous techniques and methods for binding and separatingmolecules are known and can be adapted for use with the disclosedmethods to bind and separate methylated form unmethylated DNA.

In some forms, treating the DNA sample can be accomplished by, forexample, capturing status biomarker DNA fragments and sequencing thecaptured status biomarker DNA fragments, wherein the sequencingdistinguishes cytosine from methylcytosine, wherein the level ofmethylcytosine indicates level of methylated forms of the statusbiomarkers. Examples of such forms of the methods are described inExamples 6 and 7. In some forms, the status biomarker DNA fragments canbe captured by, for example, binding DNA fragments in the DNA sample tostatus biomarker probes attached to a support. In some forms, one ormore of the status biomarker probes can specifically hybridize to one ormore repetitive DNA sequences, wherein the one or more of the statusbiomarker probes comprises degenerate sequence representing a consensussequence for a family of repetitive DNA sequences. In some forms, eachof the status biomarker probes can specifically hybridize to one or morerepetitive DNA sequences, wherein each of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, the family ofrepetitive DNA sequences can be a family of repetitive DNA sequencessuch as the repetitive DNA sequence families listed in, for example,Table 1, Table 12, or Table 13. In some forms, the one or more of thestatus biomarker probes can comprise different degenerate sequences eachrepresenting a consensus sequence for a different one of the families ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. In some forms,the one or more of the status biomarker probes can comprise at least 2,3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22,23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40,41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 55, 60, 65, 70, 75, 80, 85, 90,95, 100, 105, 110, 115, 120, 125, 130, or 135 different degeneratesequences each representing a different consensus sequence for adifferent one of the families of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 1, Table12, or Table 13. In some forms, the support can comprise, for example,gel, a bead, a magnetic bead, a plate, a slide, a surface, or amicroparticle. In some forms, DNA not captured can be separated from thecaptured status biomarker DNA fragments. In some forms, the sequencingcan be a form of SMRT sequencing.

In some forms, the method can further comprise, after capturing statusbiomarker DNA fragments and prior to sequencing the captured statusbiomarker DNA fragments, releasing the captured status biomarker DNAfragments and recapturing the released status biomarker DNA fragments.An example of such forms of the methods is described in Example 7. Insome forms, the status biomarker DNA fragments can be recaptured bybinding DNA fragments in the DNA sample to secondary status biomarkerprobes attached to a support. In some forms, one or more of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein the one or more of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, each of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein each of the status biomarker probes comprisesdegenerate sequence representing a consensus sequence for a family ofrepetitive DNA sequences. In some forms, the family of repetitive DNAsequences can be a family of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 16 andTable 17. In some forms, the family of repetitive DNA sequences can be afamily of repetitive DNA sequences listed in Table 17. For example, thefamily of repetitive DNA sequences can be the AluY, AluSx, AluSp, AluSg,or AluSc family of repetitive DNA sequences. In some forms, the one ormore of the status biomarker probes can comprise different degeneratesequences each representing a consensus sequence for a different one ofthe families of repetitive DNA sequences such as the repetitive DNAsequence families listed in, for example, Table 16 and Table 17. In someforms, the one or more of the status biomarker probes can comprisedifferent degenerate sequences each representing a consensus sequencefor a different one of the families of repetitive DNA sequences listedin Table 16 or 17, such as AluY, AluSx, AluSp, AluSg, or AluSc. In someforms, the support can comprise, for example, gel, a bead, a magneticbead, a plate, a slide, a surface, or a microparticle. In some forms,DNA not recaptured can be separated from the recaptured status biomarkerDNA fragments.

ii. Detecting the Level of Status Biomarkers

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, an array of probes specific for thestatus biomarkers. An example of such forms of the methods is describedin Example 3. This detection is useful for DNA that has been treated todifferentially amplify or retain DNA based on the methylation state. Insome forms, the array of probes can be, for example, a microarray.Myriad techniques are known for detecting and assessing nucleic acidsequences. Such techniques can be used with the disclosed methods todetect and assess status biomarkers and the status or biomarkers.Multiplex and high throughput techniques are particular useful for thispurpose. Thus, for example, the use of arrays and microarrays fordetection are particularly useful.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, amplifying the processed DNA anddetermining the ratio of cytosine to thymidine in the amplified DNA andconverting the ratio to the level of methylated forms of the statusbiomarkers. An example of such forms of the methods is described inExample 4. This detection is useful for DNA that has been treated withsodium, bisulfite. In some forms, the processed DNA can be amplifiedvia, for example, PCR amplification of the status biomarkers usingprimers specific for the status biomarkers.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, PCR amplification of the statusbiomarkers using primers specific for the status biomarkers. An exampleof such forms of the methods is described in Example 5. This detectionis useful for DNA that has been separated based on methylation of lackof methylation. In some forms, the PCR amplification can be quantitativePCR. In some forms, the PCR amplification can be nanoliter-microarrayquantitative PCR.

iii. Analysis of Groups of Status Biomarkers

In some forms, the level of the status biomarkers can be grouped into aplurality of status biomarker families, wherein the level of the statusbiomarkers in one or more of the families is analyzed, wherein theanalyzed level of the status biomarkers in the one or more of thefamilies indicates the methylation state of the status biomarkers in thefamily. In some forms, the analyzed level of the status biomarkers inone or more of the families can be the average of the levels of theindividual status biomarkers in the family. In some forms, one or moreof the status biomarker families each independently can consist of, forexample, a single class of repetitive DNA element, a single subclass ofrepetitive DNA element, a single family of repetitive DNA element, asingle subfamily of repetitive DNA element, or a combination. In someforms, the analyzed level of the status biomarkers in one or more of thefamilies can be normalized to one or more of the reference methylationstates. In some forms, the level of one or more of the status biomarkerscan be normalized to one or more of the reference methylation states. Insome forms, the level of one or more of the status biomarker familiescan be normalized to one or more of the reference methylation states. Insome forms, the status biomarkers can be grouped according to one ormore repetitive DNA sequences that the status biomarkers comprise,wherein each biomarker in each status biomarker family comprises one ormore repetitive DNA sequences that belong to a single family ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13.

iv. Reference Methylation State

In some forms, one or more of the one or more reference methylationstates can be a normal methylation state. In some forms, the normalmethylation state can be, for example, the methylation state of ahealthy subject, the average of the methylation states of healthysubjects, or the average of the methylation states of a population ofsubjects. In some forms, one or more of the one or more referencemethylation states can be, for example, the methylation state of thesame subject at a different time, the methylation state of the samesubject at an earlier time, the methylation state of the same subject ata later time, or the methylation state of one or more normal cells,tissues, organs, or a combination of the same subject. In some forms,one or more of the one or more reference methylation states can be themethylation state from non-tumor adjacent tissue. In some forms, one ormore of the one or more reference methylation states can be a normalmethylation state of a status biomarker family.

v. Determining Genetic State of Status Biomarkers

In some forms, the method can further comprise determining the geneticstate of one or more status biomarkers by, for example, comparing one ormore of the determined genetic states to one or more reference geneticstates, wherein a difference, lack of a difference, or both in one ormore of the determined genetic states and one or more of the referencegenetic states indicates one or more statuses of the subject. As usedherein, “genetic state” refers to a particular sequence or mutation inthe biomarker. Thus, for example, a particular SNP in a biomarker is agenetic state of the biomarker. In some forms, determining the geneticstate of one or more status biomarkers can be determined in one or moreof the DNA samples. The genetic state of biomarkers can be determinedusing any technique or method that can determine the sequence of abiomarker. Myriad techniques and methods for sequencing and determiningthe sequence of nucleic acids are known. Such techniques and methods canbe used with the disclosed methods.

In some forms, the source of one or more of the DNA samples can be oneor more tissues of the subject, organs of the subject, or both. In someforms, the source of one or more of the DNA samples can be a tissue ororgan of the subject. In some forms, the source of one or more of theDNA samples can be one or more cells of the subject. In some forms, thesource of one or more of the DNA samples can be one or more cells,tissue, skin, lung, head, neck, prostate, breast, ovary, brain, liver,stomach, intestine, kidney, testicle, cervix, uterus, spleen, bone,throat, esophagus, muscle, bodily fluids, blood, urine, semen, lymphaticfluid, cerebrospinal fluid, amniotic fluid, biological samples, tissueculture cells, buccal swabs, mouthwash, stool, tissues slices, biopsyaspiration, or a combination.

vi. Status of Diseases and Conditions Assessed in Subject

In some forms, the subject can be assessed for the status of wellness,level of health, risk to wellness, risk to level of health, or acombination. In some forms, the subject can be assessed for the statusof the genome. The status of the genome can be, for example, the levelof methylation of status biomarkers in the genome relative to areference or normal state. A useful reference state for this purpose canbe the average methylation state for young subjects and/or healthysubjects. In some forms, the subject can be assessed for the status ofaging, risk of aging, or both. In some forms, the subject can beassessed for the status of cancer, risk of cancer, or both. In someforms, the subject can be assessed for the status of stress response. Insome forms, the subject can be assessed for the status of diabetes, riskof diabetes, or both. In some forms, the subject can be assessed for thestatus of heart disease, risk of heart disease, or both. In some forms,the subject can be assessed for the status of genomic instability. Insome forms, the subject can be assessed for the status of tumor burden.In some forms, the subject can be assessed for the status of response totreatment. In all of these, changes in methylation state of relevantstatus biomarkers can indicate the presence or absence of the disease orcondition and/or positive or negative changes and/or risks.

vii. Timing and Comparison of Status Assessments

In some forms, the subject can be assessed for a change in one or morestatuses. In some forms, the change in one or more of the one or morestatuses can be assessed compared to an earlier assessment. In someforms, the earlier assessment can have been made at, for example, anearlier time, prior to diagnosis of a disease or condition, prior to atreatment, following diagnosis of a disease or condition, followingtreatment, or a combination. In some forms, the change in one or more ofthe one or more statuses can be assessed following the passage of time,prior to diagnosis of a disease or condition, prior to a treatment,following diagnosis of a disease or condition, following treatment, or acombination. In some forms, assessing the subject can comprise assessingone or more tissues of the subject, organs of the subject, or both. Asused herein, assessing a tissue or organ of a subject being assessed fora particular status means that the tissue or organ is assessed for thatstatus and that such assessment of the tissue or organ constitutes theassessment of the subject. In some forms, assessing the subject cancomprise assessing a tissue or organ of the subject. In some forms,assessing the subject can comprise assessing one or more cells of thesubject.

B. Method of Identifying Status Biomarkers Associated with Diseases andConditions

Status biomarkers useful for particular states, diseases, and conditionscan be identified using the disclosed methods. For example, statusbiomarkers associated with a status of a subject can be identified by,for example, determining the methylation state of one or more statusbiomarkers in one or more DNA samples, wherein the DNA samples are fromsources that are relevant to one or more specific statuses, andcomparing one or more of the determined methylation states to one ormore reference methylation states, wherein a difference in one or moreof the determined methylation states and one or more of the referencemethylation states indicates that the status biomarkers for which thedifference in the methylation states is found is a status biomarkerassociated with one or more of the specific statuses. Particularlyuseful status biomarkers can be identified by determining thestatistical significance of the change in methylation state in theaffected sample versus a relevant reference methylation state.

i. Determining Methylation State

In some forms, the methylation state can be determined by, for example,treating a DNA sample of the subject to differentiate methylated andunmethylated nucleotides, and detecting the level of methylated forms ofthe one or more status biomarkers in the treated DNA, detecting thelevel of unmethylated forms of the one or more status biomarkers in thetreated DNA, or both, wherein the level of methylated forms of thestatus biomarkers, the level of unmethylated forms of the statusbiomarkers, or both indicates the methylation state of the statusbiomarkers.

In some forms, treating the DNA sample can be accomplished by, forexample, incubating the DNA sample with one or more restrictionendonucleases and amplifying the incubated DNA, wherein the restrictionendonucleases are methylation-sensitive restriction endonucleases,wherein the level of the status biomarkers in the amplified DNA is lowerwhen the status biomarkers have reduced methylation and the level of thestatus biomarkers in the amplified DNA is higher when the statusbiomarkers have increased methylation, wherein the level of the statusbiomarkers comprise the level of methylated forms of the one or morestatus biomarkers in the treated DNA, the level of unmethylated forms ofthe one or more status biomarkers in the treated DNA, or both. Anexample of such forms of the methods is described in Example 3.

In some forms, the restriction endonucleases can further comprise atleast one methylation-dependent restriction endonuclease. In some forms,the restriction endonucleases can further comprise at least onemethylation-independent restriction endonuclease. In some forms, therestriction endonucleases can comprise AciI and HhaI. In some forms, therestriction endonucleases can comprise McrBC. In some forms, incubatingthe DNA sample with one or more endonucleases can be accomplished by,for example, incubating different aliquots of the DNA sample withdifferent restriction endonucleases. In some forms, amplifying theincubated DNA can be accomplished by, for example, multiple displacementamplification.

In some forms, treating the DNA sample can be accomplished by, forexample, processing the DNA sample with sodium bisulfite. An example ofsuch forms of the methods is described in Example 4.

In some forms, treating the DNA sample can be accomplished by, forexample, fragmenting the DNA and separating methylated DNA fromunmethylated DNA. An example of such forms of the methods is describedin Example 5. In some forms, the DNA can be fragmented by, for example,nebularization, cleavage with a restriction endonuclease, sonication, ora combination. In some forms, methylated DNA can be separated fromunmethylated DNA by, for example, binding methylated DNA with a specificbinding molecule specific for methyl groups and separating the boundform the unbound DNA. In some forms, the specific binding molecule cancomprise, for example, an antibody specific for 5-methyl cytosine,methyl-biding protein MBD1, methyl-biding protein MECP2, or acombination.

In some forms, treating the DNA sample can be accomplished by, forexample, capturing status biomarker DNA fragments and sequencing thecaptured status biomarker DNA fragments, wherein the sequencingdistinguishes cytosine from methylcytosine, wherein the level ofmethylcytosine indicates level of methylated forms of the statusbiomarkers. Examples of such forms of the methods is described inExamples 6 and 7. In some forms, the status biomarker DNA fragments canbe captured by, for example, binding DNA fragments in the DNA sample tostatus biomarker probes attached to a support. In some forms, one ormore of the status biomarker probes can specifically hybridize to one ormore repetitive DNA sequences, wherein the one or more of the statusbiomarker probes comprises degenerate sequence representing a consensussequence for a family of repetitive DNA sequences. In some forms, eachof the status biomarker probes can specifically hybridize to one or morerepetitive DNA sequences, wherein each of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, the family ofrepetitive DNA sequences can be a family of repetitive DNA sequencessuch as the repetitive DNA sequence families listed in, for example,Table 1, Table 12, or Table 13. In some forms, the one or more of thestatus biomarker probes can comprise different degenerate sequences eachrepresenting a consensus sequence for a different one of the families ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13. In some forms,the one or more of the status biomarker probes can comprise at least 2,3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22,23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40,41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 55, 60, 65, 70, 75, 80, 85, 90,95, 100, 105, 110, 115, 120, 125, 130, or 135 different degeneratesequences each representing a different consensus sequence for adifferent one of the families of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 1, Table12, or Table 13. In some forms, the support can comprise, for example,gel, a bead, a magnetic bead, a plate, a slide, a surface, or amicroparticle. In some forms, DNA not captured can be separated from thecaptured status biomarker DNA fragments. In some forms, the sequencingcan be a form of SMRT sequencing.

In some forms, the method can further comprise, after capturing statusbiomarker DNA fragments and prior to sequencing the captured statusbiomarker DNA fragments, releasing the captured status biomarker DNAfragments and recapturing the released status biomarker DNA fragments.An example of such forms of the methods is described in Example 7. Insome forms, the status biomarker DNA fragments can be recaptured bybinding DNA fragments in the DNA sample to secondary status biomarkerprobes attached to a support. In some forms, one or more of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein the one or more of the status biomarker probescomprises degenerate sequence representing a consensus sequence for afamily of repetitive DNA sequences. In some forms, each of the statusbiomarker probes can specifically hybridize to one or more repetitiveDNA sequences, wherein each of the status biomarker probes comprisesdegenerate sequence representing a consensus sequence for a family ofrepetitive DNA sequences. In some forms, the family of repetitive DNAsequences can be a family of repetitive DNA sequences such as therepetitive DNA sequence families listed in, for example, Table 16 andTable 17. In some forms, the family of repetitive DNA sequences can be afamily of repetitive DNA sequences listed in Table 17. For example, therepetitive DNA sequence family can be the AluY, AluSx, AluSp, AluSg, orAluSc family of repetitive DNA sequences. In some forms, the one or moreof the status biomarker probes can comprise different degeneratesequences each representing a consensus sequence for a different one ofthe families of repetitive DNA sequences such as the repetitive DNAsequence families listed in, for example, Table 16 and Table 17. In someforms, the one or more of the status biomarker probes can comprisedifferent degenerate sequences each representing a consensus sequencefor a different one of the families of repetitive DNA sequences listedin Table 16 or 17, such as AluY, AluSx, AluSp, AluSg, or AluSc. In someforms, the support can comprise, for example, gel, a bead, a magneticbead, a plate, a slide, a surface, or a microparticle. In some forms,DNA not recaptured can be separated from the recaptured status biomarkerDNA fragments.

ii. Detecting the Level of Status Biomarkers

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, an array of probes specific for thestatus biomarkers. An example of such forms of the methods is describedin Example 3. In some forms, the array of probes can be, for example, amicroarray.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, amplifying the processed DNA anddetermining the ratio of cytosine to thymidine in the amplified DNA andconverting the ratio to the level of methylated forms of the statusbiomarkers. An example of such forms of the methods is described inExample 4. In some forms, the processed DNA can be amplified via, forexample, PCR amplification of the status biomarkers using primersspecific for the status biomarkers.

In some forms, detecting the level of the status biomarkers can beaccomplished via, for example, PCR amplification of the statusbiomarkers using primers specific for the status biomarkers. In someforms, the PCR amplification can be quantitative PCR. An example of suchforms of the methods is described in Example 5. In some forms, the PCRamplification can be nanoliter-microarray quantitative PCR.

iii. Analysis of Groups of Status Biomarkers

In some forms, the level of the status biomarkers can be grouped into aplurality of status biomarker families, wherein the level of the statusbiomarkers in one or more of the families is analyzed, wherein theanalyzed level of the status biomarkers in the one or more of thefamilies indicates the methylation state of the status biomarkers in thefamily. In some forms, the analyzed level of the status biomarkers inone or more of the families can be the average of the levels of theindividual status biomarkers in the family. In some forms, one or moreof the status biomarker families each independently can consist of, forexample, a single class of repetitive DNA element, a single subclass ofrepetitive DNA element, a single family of repetitive DNA element, asingle subfamily of repetitive DNA element, or a combination. In someforms, the analyzed level of the status biomarkers in one or more of thefamilies can be normalized to one or more of the reference methylationstates. In some forms, the level of one or more of the status biomarkerscan be normalized to one or more of the reference methylation states. Insome forms, the level of one or more of the status biomarker familiescan be normalized to one or more of the reference methylation states. Insome forms, the status biomarkers can be grouped according to one ormore repetitive DNA sequences that the status biomarkers comprise,wherein each biomarker in each status biomarker family comprises one ormore repetitive DNA sequences that belong to a single family ofrepetitive DNA sequences such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13.

iv. Reference Methylation State

In some forms, one or more of the one or more reference methylationstates can be a normal methylation state. In some forms, the normalmethylation state can be, for example, the methylation state of ahealthy subject, the average of the methylation states of healthysubjects, or the average of the methylation states of a population ofsubjects. In some forms, one or more of the one or more referencemethylation states can be, for example, the methylation state of thesame subject at a different time, the methylation state of the samesubject at an earlier time, the methylation state of the same subject ata later time, or the methylation state of one or more normal cells,tissues, organs, or a combination of the same subject. In some forms,one or more of the one or more reference methylation states can be themethylation state from non-tumor adjacent tissue. In some forms, one ormore of the one or more reference methylation states can be a normalmethylation state of a status biomarker family.

v. Step of Determining Genetic State of Status Biomarkers

In some forms, the method can further comprise determining the geneticstate of one or more status biomarkers by, for example, comparing one ormore of the determined genetic states to one or more reference geneticstates, wherein a difference, lack of a difference, or both in one ormore of the determined genetic states and one or more of the referencegenetic states indicates one or more statuses of the subject. In someforms, determining the genetic state of one or more status biomarkerscan be determined in one or more of the DNA samples.

In some forms, the source of one or more of the DNA samples can be oneor more tissues of the subject, organs of the subject, or both. In someforms, the source of one or more of the DNA samples can be a tissue ororgan of the subject. In some forms, the source of one or more of theDNA samples can be one or more cells of the subject. In some forms, thesource of one or more of the DNA samples can be one or more cells,tissue, skin, lung, head, neck, prostate, breast, ovary, brain, liver,stomach, intestine, kidney, testicle, cervix, uterus, spleen, bone,throat, esophagus, muscle, bodily fluids, blood, urine, semen, lymphaticfluid, cerebrospinal fluid, amniotic fluid, biological samples, tissueculture cells, buccal swabs, mouthwash, stool, tissues slices, biopsyaspiration, or a combination.

C. Method of Producing Status Biomarker Probes

The disclosed methods can be used to design and/or produce probes forstatus biomarkers, including status biomarker capture probes. Forexample, status biomarker probes can be designed by, for example,selecting a subset of repetitive DNA sequence loci from a set ofrepetitive DNA sequence loci, and generating a set of status biomarkerprobe sequences. Status biomarker probes can then be produced bysynthesizing one or more status biomarker probes from the statusbiomarker probe sequences. In some forms, the repetitive DNA sequenceloci in the set of repetitive DNA sequence loci can belong to a singleone of the families of repetitive DNA sequence such as the repetitiveDNA sequence families listed in, for example, Table 1, Table 12, orTable 13, wherein the subset of repetitive DNA sequence loci can beselected by identifying those repetitive DNA sequence loci that comprisea repetitive DNA sequence belonging to one of the families of repetitiveDNA sequences such as the repetitive DNA sequence families listed in,for example, Table 16 and Table 17.

In some forms, each status biomarker probe sequence in the set can havea length of, for example, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65,70, 75, 80, 85, 90, 95, or 100 bases or more, wherein each statusbiomarker probe represented in the set of status biomarker probesequences can hybridize to, for example, at least 1%, 2%, 3%, 4%, 5%,6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15% of the repetitive DNAsequence loci in the selected subset of repetitive DNA sequence loci. Insome forms, each status biomarker probe can have the sequence of one ofthe status biomarker probe sequences.

In some forms, the repetitive DNA sequence loci in the set of repetitiveDNA sequence loci can belong to a single one of the families ofrepetitive DNA sequence LTR54B, MER11B, MER34B, LTR56, THE1B, HERV9,LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D, HERVK11, LTR10B, HERVK22,MER6, MER66C, MLT1G1, MER4D, and MLTD2. In some forms, the repetitiveDNA sequence in the subset of repetitive DNA sequence loci can belong toone of the families of repetitive DNA sequences listed in Table 16 or17, such as AluY, AluSx, AluSp, AluSg, AluSc, LTR9, or LTR9B.

In some forms, the method can further comprise selecting one or moreadditional subsets of repetitive DNA sequence loci each from a differentadditional set of repetitive DNA sequence loci, generating one or moreadditional sets of status biomarker probe sequences each based on one ofthe one or more additional subsets, and synthesizing one or moreadditional status biomarker probes, wherein each additional statusbiomarker probe has the sequence of one of the additional statusbiomarker probe sequences. In some forms, the repetitive DNA sequenceloci in each additional set of repetitive DNA sequence loci canindependently belong to a different single one of the families ofrepetitive DNA sequence such as the repetitive DNA sequence familieslisted in, for example, Table 1, Table 12, or Table 13, wherein therepetitive DNA sequence loci in the set of repetitive DNA sequence lociand in each additional set of repetitive DNA sequence loci belong todifferent families of repetitive DNA sequence.

In some forms, the repetitive DNA sequence loci in the each additionalset of repetitive DNA sequence loci can independently belong to a singleone of the families of repetitive DNA sequence LTR54B, MER11B, MER34B,LTR56, THE1B, HERV9, LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D,HERVK11, LTR10B, HERVK22, MER6, MER66C, MLT1G1, MER4D, and MLTD2. Insome forms, each status biomarker probe sequence in the set can have alength of, for example, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70,75, 80, 85, 90, 95, or 100 bases or more. In some forms, each statusbiomarker probe represented in the set of status biomarker probesequences can hybridize to, for example, at least 1%, 2%, 3%, 4%, 5%,6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15% of the repetitive DNAsequence loci in the selected subset of repetitive DNA sequence loci. Insome forms, the set of status biomarker probe sequences can comprisefrom 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19,20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 34, 35, 36, 38, 40, 42,44, 45, 46, 48, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 110, 120,130, 140, 150, 160, 170, 180, 190, or 200 to 1, 2, 3, 4, 5, 6, 7, 8, 9,10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27,28, 29, 30, 32, 34, 35, 36, 38, 40, 42, 44, 45, 46, 48, 50, 55, 60, 65,70, 75, 80, 85, 90, 95, 100, 110, 120, 130, 140, 150, 160, 170, 180,190, or 200 status biomarker probe sequences. In some forms, the set ofstatus biomarker probe sequences can comprise from 5 to 100 statusbiomarker probe sequences. In some forms, the set of status biomarkerprobe sequences can comprise from 10 to 100 status biomarker probesequences. In some forms, one or more of the additional sets of statusbiomarker probe sequences each can comprise from 1 to 100 statusbiomarker probe sequences. In some forms, the one or more additionalsets of status biomarker probe sequences each can comprise from 5 to 100status biomarker probe sequences. In some forms, the one or moreadditional sets of status biomarker probe sequences each can comprisefrom 10 to 100 status biomarker probe sequences.

Status biomarker probes can be designed and produce for any desiredstatus biomarker or family of status biomarkers. For example, captureprobes for preferred status biomarkers can be designed by:

a. obtaining the RepeatMasker annotation for all members of a preferredstatus biomarker family, said annotation comprising the genomiccoordinates of each member of the chosen repetitive element family, aswell as the annotated DNA sequence;

b. re-organizing the DNA sequences in the list so that all are in the 5′to 3′ orientation;

c. examining each candidate status biomarker locus by defining a windowof 1000 bases, centered in the middle of the repetitive elementsequence, and then performing a query of the RepeatMasker annotation tofind any other repeats present in the window, whereby those co-localizedor neighbor repetitive elements belong to a list of preferred neighborfamilies (such as those listed in Table 16 and Table 17);

d. choosing the subset of the coordinates corresponding to repetitiveelements satisfying the criteria that they contain a neighbor present inthe list of neighbors; this is the preferred candidate coordinate andsequence list;

e. generating a list, using standard computational tools, of between 1and 100 oligonucleotides each with a length of 100 bases or more, eachprobe capable of forming duplex structures with more than 5% of thesequences present in the preferred candidate sequence list; the duplexstructures can contain several mismatches, as long as they are deemedcapable of forming a duplex stable enough for performing sequencecapture (design criteria for such capture probes are published and wellknown in the art).

The designed capture probes can be produced and used by, for example,performing synthesis (as DNA or RNA) of the designed oligonucleotides(between 1 and 100 different sequences), and utilizing theseoligonucleotides, as a mixture in solution, or as a collection of probesbound on a microarray surface, for capturing fragmented genomic DNA froma biological sample, using methods well know in the published art.

D. Statistical Analysis

1. Random Forest

Random forest (Breiman 2001) is a classifier that is consisted of manydecision trees. The following is the procedure of constructing anindividual decision tree. Suppose there are n observations and pvariables (or features) in the data set. (1) Randomly draw a bootstrapsample of size n with replacement from the data set. This set is calledthe training set and is used to construct a decision tree. (2) Apre-specified fixed number of variables, say m, is drawn at random fromthe p variables. The parameter m is chosen such that it is much smallerthan p. (3) A tree is constructed from the top down. At each node, thevariable that yields the best split is chosen to split the node. (4)Repeat step 3 to grow the tree until no split can further improve theclassification. No pruning is conducted.

To classify a new case, run it through all trees in the forest. Eachtree gives a classification, or called a “vote”. And the finalclassification given by the forest takes the majority votes of alltrees. To obtain an estimate of error rates, the set of observationsthat are not sampled in each tree, which is called the out-of-bag (OOB)set and is about one third of the original data, is used for crossvalidation. More specifically, for each OOB case, run it down thedecision tree and obtain a classification or a vote. At the end of allruns, each case has the final classification by simple majority OOBvotes. This gives an estimate of the error rates.

The advantages of random forest include: excellent classificationaccuracy; fast computation speed; efficient handling of large data sets;providing proximities between pairs of cases; generating importancemeasures for all variables; no need of extra test sets.

2. Support Vector Machine

In Support Vector Machine (SVM) (Vapnik 1998) a set of features thatdescribes an observation is called a vector. SVM classifies observationsby construct hyperplanes that optimally separate the data into differentclasses, i.e., vectors of different classes are on different sides ofthe hyperplanes. The vectors close to the hyperplanes are called supportvectors. The goal of SVM is to find optimal hyperplanes by maximizingthe distances between the support vectors and the hyperplanes. SVM iscomputationally efficient and can handle large data sets.

Support Vector Machine-Recursive Feature Elimination (SVM-RFE) (Guyon etal., 2002) selects features in a sequential backward elimination manner,which starts with all the features and discards one feature at a time.

3. Others

Several statistical analyses can be performed. A list of other analysesincludes, but is not limited to, Linear discriminant analysis (McLachlan2004), Logistic regression (Agresti 2002), Classification and RegressionTrees (CART) (Breiman 1984), Neural Networks (Marques de Sa 2001),Bayesian Additive Regression Trees (Chipman 2006).

A. Detection

Any analyte, including the various compounds and compositions disclosedherein, can be detected. For example, status biomarkers, repetitive DNAsequence, repetitive DNA sequence loci, families of status biomarkers,families of repetitive DNA sequences, etc. can be detected. Detection ofstatus biomarkers can be by, for example, detecting the level, amount,presence, or a combination, of the analyte in a sample or assay. Asdescribed below and elsewhere herein, the manner of detection of statusbiomarkers can be based on the treatment of DNA samples and generallycan be in service of detecting and determining the methylation state andpresence of methylation in status biomarkers. Detection of the disclosedcompounds and compositions can be accomplished in any of a variety ofways and using any of a variety of techniques. Many such detectiontechniques are known and can be readily adapted for use in the disclosedmethods. In most cases, the disclosed methods do not depend onparticular techniques of detection. However, certain techniques andreagents are useful for detecting different types of compounds andcompositions. Those of skill in the art are aware of the selection ofparticular techniques for the detection of particular compounds andcompositions. Detection can, but need not, involve an element ofquantitation.

Detection can be of a class of compounds or compositions or of specificcompounds or compositions. Although the disclosed methods generallyinvolve detection of specific compounds and compositions, such asspecific DNA molecules, the disclosed methods can also be used to detectclasses or groups of compounds or compositions, generally via one ormore common properties. In other forms, multiple different specificcompounds and/or compositions can be detected. Such detectionaccomplished in the same assay or run (or in separate assays of runsperformed at the same time), can generally be referred to as multiplexdetection.

Detection can involve or include, for example, measuring, sequencing,identification, or a combination. Measurement is useful for determiningabundances and levels of an analyte in a sample. Sequencing is usefulfor identifying nucleic acid sequence and molecules. Uses and forms ofdetection in the context of the disclosed methods are also describedelsewhere herein.

Detection can involve a variety of forms. For example, detecting one ormore of the status biomarkers can be accomplished using a probecorresponding to a unique sequence in the status biomarker.

1. Measuring

Any analyte, including the various compounds and compositions disclosedherein, can be detected by measuring, for example, the level, amount,presence, or a combination, of the analyte in a sample or assay. Forexample, the methylation state and/or level of status biomarkers,repetitive DNA sequence, repetitive DNA sequence loci, families ofstatus biomarkers, families of repetitive DNA sequences, etc. can bemeasured. Measurement of the level, amount, presence, or a combination,of the analyte can also be accomplished when detection is not anexplicit object. Similar to detection, measurement of the disclosedcompounds and compositions can be accomplished in any of a variety ofways and using any of a variety of techniques. Many such measurementtechniques are known and can be readily adapted for use in the disclosedmethods. In most cases, the disclosed methods do not depend onparticular techniques of measurement. Measurement can involve an elementof quantitation. Many techniques are known for measuring abundances andlevels of an analyte in a sample. Such techniques can be adapted for usewith the disclosed methods.

2. Sequencing

Nucleic acid sequences and molecules can be detected, measured,identified, and so on, via sequencing. In the context of nucleic acidsequences and molecules, sequencing refers to the determination oridentification of some or all of the nucleotide base sequence of anucleic acid sequence or molecule. Numerous techniques for nucleic acidsequencing are known and can be used with the disclosed methods.Examples of useful types of sequencing techniques include techniquesinvolving detection of individual nucleotide bases (such as by detectionof terminated primer extension products) and detection of multiplenucleotide bases (such as by hybridization of probes of known sequence).Any suitable sequencing technique can be used with the disclosedmethods. Sequencing is particularly useful for identifying nucleic acidsequences and molecules.

Particularly useful sequencing techniques are those that can generatelarge amounts of sequence data quickly and accurately. High-throughputand ultra-high throughput sequencing provides a number of advantages,the main two being faster results and the ability to detect and measurea large number of nucleic acid molecules. Examples of usefulhigh-throughput sequencing techniques include Solexa™ sequencing, SOLiD™sequencing, and sequencing using a Illumina Genome Analyzer™ or a 454™.

Illumina Sequencing technology is based on massively parallel sequencingof millions of fragments using reversible terminator-based sequencingchemistry. Illumina

Sequencing technology relies on the attachment of randomly fragmentedgenomic DNA to a planar, optically transparent surface. Attached DNAfragments are extended and bridge amplified to create an ultra-highdensity sequencing flow cell with hundreds of millions of clusters, eachcontaining ˜1,000 copies of the same template. These templates aresequenced using a four-color DNA sequencing-by-synthesis technology thatemploys reversible terminators with removable fluorescent dyes. Thisallows high accuracy and true base-by-base sequencing, eliminatingsequence-context specific errors and enabling sequencing throughhomopolymers and repetitive sequences. High-sensitivity fluorescencedetection is achieved using laser excitation and total internalreflection optics. Sequence reads are aligned against a reference genomeand genetic differences are called using specially developed dataanalysis pipeline software.

The SOLiD System involves depositing beads containing template DNAfragments to be sequenced onto a glass slide. Primers hybridize to asequence within the template. A set of four fluorescently labeleddi-base probes compete for ligation to the sequencing primer.Specificity of the di-base probe is achieved by interrogating every 1stand 2nd base in each ligation reaction. Multiple cycles of ligation,detection and cleavage are performed with the number of cyclesdetermining the eventual read length. Following a series of ligationcycles, the extension product is removed and the template is reset witha primer complementary to the n−1 position for a second round ofligation cycles. Five rounds of primer reset are completed for eachsequence tag. Through the primer reset process, each base isinterrogated in two independent ligation reactions by two differentprimers. For example, the base at read position 5 is assayed by primernumber 2 in ligation cycle 2 and by primer number 3 in ligation cycle 1.This dual interrogation is fundamental to the unmatched accuracycharacterized by the SOLiD System.

The SOLiD System relies on open slide format and flexible bead densitiesto enable increases in throughput with protocol and chemistryoptimizations. The SOLiD System provides system accuracy greater than99.94%, due to 2 base encoding. 2 Base encoding enables unique errorchecking capability, providing higher confidence in each call. TheSOLiD™ System can generate over 20 gigabases and 400M tags per run. Theindependent flow cell configuration of the SOLID Analyzer two completelyindependent experiments in a single run. The combination of multipleslide configuration and sample multiplexing capability enables you toanalyze multiple samples cost effectively for a variety of applications.The SOLiD System supports sample preparation for mate-paired librarieswith insert sizes ranging from 600 bp up to 10 kbp. This broad range ofinsert sizes combined with ultra high throughput and flexible 2 flowcell configuration enables more precise characterization of structuralvariation across the genome.

3. Identification

In the context of the disclosed methods, identification refers todetermination of the particular type or instance of a thing, such as ofthe disclosed status biomarkers, repetitive DNA sequence, repetitive DNAsequence loci, families of status biomarkers, families of repetitive DNAsequences, etc. Thus, for example, a status biomarker can be identifiedby determining part of its sequence, where the sequence ischaracteristic of that status biomarker. In the disclosed method, anumber of components are, or can be designed, to correspond to, becomplementary to, or be for particular other components. By suchcorrespondence, identification of one component can often allowidentification of any other components that correspond. For example, aprobe can be designed with a target complement sequence that iscomplementary to a particular sequence of a status biomarker ofinterest. The probe can be said to correspond to, or to be for, thestatus biomarker of interest. When used in the disclosed methods,detection or identification of the probe can result in the detection ofthe presence, or identification, of the corresponding status biomarkerin the sample.

DEFINITIONS

The term “hit” refers to a test compound that shows desired propertiesin an assay. The term “test compound” refers to a chemical to be testedby one or more screening method(s) as a putative modulator. A testcompound can be any chemical, such as an inorganic chemical, an organicchemical, a protein, a peptide, a carbohydrate, a lipid, or acombination thereof. Usually, various predetermined concentrations oftest compounds are used for screening, such as 0.01 micromolar, 1micromolar and 10 micromolar. Test compound controls can include themeasurement of a signal in the absence of the test compound orcomparison to a compound known to modulate the target.

The terms “higher,” “increases,” “elevates,” or “elevation” refer toincreases above basal levels, e.g., as compared to a control. The terms“low,” “lower,” “reduces,” or “reduction” refer to decreases below basallevels, e.g., as compared to a control.

The term “modulate” as used herein refers to the ability of a compoundto change an activity in some measurable way as compared to anappropriate control. As a result of the presence of compounds in theassays, activities can increase or decrease as compared to controls inthe absence of these compounds. Preferably, an increase in activity isat least 25%, more preferably at least 50%, most preferably at least100% compared to the level of activity in the absence of the compound.Similarly, a decrease in activity is preferably at least 25%, morepreferably at least 50%, most preferably at least 100% compared to thelevel of activity in the absence of the compound. A compound thatincreases a known activity is an “agonist”. One that decreases, orprevents, a known activity is an “antagonist.”

The term “inhibit” means to reduce or decrease in activity orexpression. This can be a complete inhibition or activity or expression,or a partial inhibition. Inhibition can be compared to a control or to astandard level. Inhibition can be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12,13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30,31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48,49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66,67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84,85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, or 100%.

The term “monitoring” as used herein refers to any method in the art bywhich an activity can be measured.

The term “providing” as used herein refers to any means of adding acompound or molecule to something known in the art. Examples ofproviding can include the use of pipettes, pipettemen, syringes,needles, tubing, guns, etc. This can be manual or automated. It caninclude transfection by any mean or any other means of providing nucleicacids to dishes, cells, tissue, cell-free systems and can be in vitro orin vivo.

The term “preventing” as used herein refers to administering a compoundprior to the onset of clinical symptoms of a disease or conditions so asto prevent a physical manifestation of aberrations associated with thedisease or condition.

The term “in need of treatment” as used herein refers to a judgment madeby a caregiver (e.g. physician, nurse, nurse practitioner, or individualin the case of humans; veterinarian in the case of animals, includingnon-human mammals) that a subject requires or will benefit fromtreatment. This judgment is made based on a variety of factors that arein the realm of a care giver's expertise, but that include the knowledgethat the subject is ill, or will be ill, as the result of a conditionthat is treatable by the disclosed compounds.

As used herein, “subject” includes, but is not limited to, animals,plants, bacteria, viruses, parasites and any other organism or entity.The subject can be a vertebrate, more specifically a mammal (e.g., ahuman, horse, pig, rabbit, dog, sheep, goat, non-human primate, cow,cat, guinea pig or rodent), a fish, a bird or a reptile or an amphibian.The subject can be an invertebrate, more specifically an arthropod(e.g., insects and crustaceans). The term does not denote a particularage or sex. Thus, adult and newborn subjects, as well as fetuses,whether male or female, are intended to be covered. A patient refers toa subject afflicted with a disease or disorder. The term “patient”includes human and veterinary subjects.

By “treatment” and “treating” is meant the medical management of asubject with the intent to cure, ameliorate, stabilize, or prevent adisease, pathological condition, or disorder. This term includes activetreatment, that is, treatment directed specifically toward theimprovement of a disease, pathological condition, or disorder, and alsoincludes causal treatment, that is, treatment directed toward removal ofthe cause of the associated disease, pathological condition, ordisorder. In addition, this term includes palliative treatment, that is,treatment designed for the relief of symptoms rather than the curing ofthe disease, pathological condition, or disorder; preventativetreatment, that is, treatment directed to minimizing or partially orcompletely inhibiting the development of the associated disease,pathological condition, or disorder; and supportive treatment, that is,treatment employed to supplement another specific therapy directedtoward the improvement of the associated disease, pathologicalcondition, or disorder. It is understood that treatment, while intendedto cure, ameliorate, stabilize, or prevent a disease, pathologicalcondition, or disorder, need not actually result in the cure,ameliorization, stabilization or prevention. The effects of treatmentcan be measured or assessed as described herein and as known in the artas is suitable for the disease, pathological condition, or disorderinvolved. Such measurements and assessments can be made in qualitativeand/or quantitative terms. Thus, for example, characteristics orfeatures of a disease, pathological condition, or disorder and/orsymptoms of a disease, pathological condition, or disorder can bereduced to any effect or to any amount.

A cell can be in vitro. Alternatively, a cell can be in vivo and can befound in a subject. A “cell” can be a cell from any organism including,but not limited to, a bacterium.

By the term “effective amount” of a compound as provided herein is meanta nontoxic but sufficient amount of the compound to provide the desiredresult. As will be pointed out below, the exact amount required willvary from subject to subject, depending on the species, age, and generalcondition of the subject, the severity of the disease that is beingtreated, the particular compound used, its mode of administration, andthe like. Thus, it is not possible to specify an exact “effectiveamount.” However, an appropriate effective amount can be determined byone of ordinary skill in the art using only routine experimentation.

By “pharmaceutically acceptable” is meant a material that is notbiologically or otherwise undesirable, i.e., the material can beadministered to an individual along with the selected compound withoutcausing any undesirable biological effects or interacting in adeleterious manner with any of the other components of thepharmaceutical composition in which it is contained.

It is understood that the disclosed method and compositions are notlimited to the particular methodology, protocols, and reagents describedas these may vary. It is also to be understood that the terminology usedherein is for the purpose of describing particular embodiments only, andis not intended to limit the scope of the present invention which willbe limited only by the appended claims.

It must be noted that as used herein and in the appended claims, thesingular forms “a”, “an”, and “the” include plural reference unless thecontext clearly dictates otherwise. Thus, for example, reference to “astatus biomarker” includes a plurality of such status biomarkers,reference to “the status biomarker” is a reference to one or more statusbiomarkers and equivalents thereof known to those skilled in the art,and so forth.

“Optional” or “optionally” means that the subsequently described event,circumstance, or material may or may not occur or be present, and thatthe description includes instances where the event, circumstance, ormaterial occurs or is present and instances where it does not occur oris not present.

Ranges may be expressed herein as from “about” one particular value,and/or to “about” another particular value. When such a range isexpressed, also specifically contemplated and considered disclosed isthe range from the one particular value and/or to the other particularvalue unless the context specifically indicates otherwise. Similarly,when values are expressed as approximations, by use of the antecedent“about,” it will be understood that the particular value forms another,specifically contemplated embodiment that should be considered disclosedunless the context specifically indicates otherwise. It will be furtherunderstood that the endpoints of each of the ranges are significant bothin relation to the other endpoint, and independently of the otherendpoint unless the context specifically indicates otherwise. Finally,it should be understood that all of the individual values and sub-rangesof values contained within an explicitly disclosed range are alsospecifically contemplated and should be considered disclosed unless thecontext specifically indicates otherwise. The foregoing appliesregardless of whether in particular cases some or all of theseembodiments are explicitly disclosed.

Unless defined otherwise, all technical and scientific terms used hereinhave the same meanings as commonly understood by one of skill in the artto which the disclosed method and compositions belong. Although anymethods and materials similar or equivalent to those described hereincan be used in the practice or testing of the present method andcompositions, the particularly useful methods, devices, and materialsare as described. Publications cited herein and the material for whichthey are cited are hereby specifically incorporated by reference.Nothing herein is to be construed as an admission that the presentinvention is not entitled to antedate such disclosure by virtue of priorinvention. No admission is made that any reference constitutes priorart. The discussion of references states what their authors assert, andapplicants reserve the right to challenge the accuracy and pertinency ofthe cited documents. It will be clearly understood that, although anumber of publications are referred to herein, such reference does notconstitute an admission that any of these documents forms part of thecommon general knowledge in the art.

Throughout the description and claims of this specification, the word“comprise” and variations of the word, such as “comprising” and“comprises,” means “including but not limited to,” and is not intendedto exclude, for example, other additives, components, integers or steps.

Those skilled in the art will recognize, or be able to ascertain usingno more than routine experimentation, many equivalents to the specificembodiments of the method and compositions described herein. Suchequivalents are intended to be encompassed by the following claims.

EXAMPLES A. Example 1 Combined Repetitive DNA Biomarkers for MeasuringGenomic Instability, Stress, Aging, Cancer Risk, Tumor Burden, andResponse to Therapy

1. Introduction

There is a need for sensitive and accurate assays capable of detectingthe presence of abnormal cells in tissues. Such abnormal cells mayrepresent in aging tissues, dysplasia, carcinoma in situ, cancer, ormetastatic cancer. There is also a need for accurate assays capable ofreporting the response of patients to therapies whose purpose is to killtumor cells, or to reduce the number of abnormal or dysplastic cells inan organ compartment.

The detection of circulating DNA derived from dead or damaged cells isan attractive strategy for implementing assays that are useful for theaforementioned purposes. DNA is a very stable molecule, and can persistfor a long time in the circulation. Thus, when tumor cells or otherabnormal cells die, the DNA may be detected in the circulation. There isa large literature reporting the detection in the circulating of DNAderived from tumors, or from abnormal cells. Recently Sunami et al(2008) reported the quantification of LINE-1 in circulating DNA as amolecular biomarker of breast cancer. An earlier report by Rago et al.(2007) had reported the assessment of human tumor burdens in mousexenografts by the analysis of circulating human-specific LINE-1 DNA. Inthe mouse study, a spike in the amount of human LINE-1 DNA present inplasma was shown to increase after tumor cytotoxic therapy,demonstrating the utility of this biomarker for monitoring drugresponses. In both of these studies the detection of circulating DNA isfacilitated by the fact that each dying cell releases thousands ofmolecules of LINE-1 DNA, and therefore the limit of detection of theseassays corresponds to a relatively small number of cells of interest.

Recently Korshunova et al (2008) reported the results of a comprehensivemethylation pattern analysis from breast cancer clinical tissues andsera obtained using massively parallel bisulphite pyrosequencing of fourdifferent gene loci in the human genome. The detailed sequencinganalysis of more than 700,000 DNA fragments derived from more than 50individuals (cancer and cancer-free) revealed an unappreciatedcomplexity of genomic cytosine-methylation patterns in both tissuederived and circulating DNAs. Key observations of this study were asfollows: First, there were no tumor-specific molecular methylationsequence patterns obtained from any of the four tested loci. Tumors andcancer-free tissues as well as sera of cancer-free individuals containednearly every conceivable cytosine methylation pattern. A great varietyof methylated molecules were present in all samples, yet no special typeof methylation pattern could be found in a statistically meaningful wayexclusively in cancerous or exclusively in normal tissues (or serum). Atall four tested loci, while there were no tumor-specific molecules,there were different tumor-specific loads of abnormally methylated DNAmolecules. The second important finding of the work was that the levelsof methylation vary greatly among tumor samples, but yet, littlevariation in methylation levels was found in samples consideredhistologically normal. The third important observation of this studyinvolved the quantification of the background level of circulating,abnormally methylated molecules in cancer-free patient sera. Accordingto cancer-specific mutation-based estimations, tumor DNA in serum atearly stages of disease is present at a relative abundance of about 12haploid genomes for every 10,000 somatically normal haploid genomes(0.12%) or less. Expected methylation signals from such minute amountsare so close to the level of background (in most cases around severaltens of the percent) that robust detection of tumor-shed DNA wasproblematic, especially in the case of an epigenetically complexbackground.

Over time, many laboratories have been identifying, and will continue toidentify biomarkers that are indicative of aging, dysplasia, or cancer.A common property of the majority of these cancer markers is that theyvary depending on the tissue of origin. For example, Ince et al. (2007)have published findings that indicate that transformation of differentbreast human breast epithelial cell types leads to distinct tumorphenotypes. This is the case because tumor phenotype tends to resembleprogenitor tissue due to natural lineage differentiation relationships.The present disclosure provides methods of identifying biomarkers thatcan be of general utility in detecting all types of tumors, such thatthey will serve for detection of any tumor type, as well as for thedetection of dysplasia in all types of tissues.

Changes in DNA methylation patterns of non-coding genomic compartmentsof cancer cells have been explored. The analysis of repetitive DNA incancers of the head and neck were focused on. Kurshunova et al. (2008)did not examine the methylation abnormalities of repetitive DNA. Mostreported studies on DNA methylation of repetitive elements have measuredthe methylation level of repetitive elements by obtaining averagemetrics, representative of mixtures of thousands of different repetitiveelements. A novel method that reports the DNA methylation level of eachindividual locus harboring a repetitive DNA element was utilized. Themethod used for this analysis provided a convenient tool to survey themethylation status of individual repetitive elements.

2. Results

i. Methylation Patterns of Major Classes and Families of DNA Repeats

The DNA methylation profiles of 33 tumors and 17 non-tumor adjacenttissue samples obtained from patients with head and neck squamouscarcinoma (HNSCC) were analyzed. DNA methylation profiles from thebuccal epithelia of 10 normal individuals were also generated, whichserved as controls. A novel microarray method for analysis of DNAmethylation, based on the use of methylation sensitive as well asmethylation dependent endonucleases, enables the interrogation ofmethylation levels in all compartments of the genome, includingrepetitive elements. Analysis of a substantial set of samples ofsquamous carcinomas of the head and neck, as well as non-tumor adjacenttissue and normal controls, reveals a complex framework of epigeneticdysregulation, where loss of methylation differentially affect distinctfamilies of repetitive elements. Predominantly the younger,primate-specific members of retroelement families suffer the mostdramatic loss of methylation, with the exception of some extremelyyoung, human-specific retroelements. These complex patterns ofdifferential susceptibility to disruption of silencing are probably aresult of the natural history of evolutionary domestication ofretroelements in genomes, in interplay with a minimal time requirementfor strong silencing to be established. Primate-specific subfamilies ofLINE-1 elements appear to suffer a particularly pronounced loss ofmethylation in tumors, with the most dramatic changes apparentlyobserved for those primate retroelements with conserved promoter regionsand longer sequences.

ii. Repetitive Elements as Cancer Biomarkers.

DNA methylation status of repetitive elements has been used asbiomarkers for cancer risk. The majority of these studies have focusedon the DNA methylation status of Line-1 elements, while a few haveutilized Alu elements instead. A sampling of seven exemplarypublications on this subject was examined, and five pairs of differentDNA primer sequences were identified that have been utilized to amplifyLine-1 DNA sequences, typically after treatment of the DNA with sodiumbisulfite. Using the computer program FASTA, the positions in the humangenome where these five different sets of primers are perfectly alignedwere identified, and predicted the exact composition of the amplifiedrepetitive elements, from the standpoint of repeat masker annotation.The sequences that are predicted to be amplified by the polymerase chainreaction in every case represent a complex mixture of Line-1 elementscorresponding to different families of different evolutionary age. Thelineages that are most highly represented, shown in the table, are L1 HS(human specific) and L1PA2, a relatively recent lineage that originatedin simians approximately 7.6 millions years ago (see Table 2).

TABLE 2 A compilation of observations about ages of lineages withinfamilies of repetitive elements Estimated age of Element Elementappearance in the Family subfamily genome (MYA) references L1PA L1PA13.1 Table 1 in Khan et al. 2006 L1PA L1PA2 7.6 Table 1 in Khan et al.2006 L1PA L1PA3 12.5 Table 1 in Khan et al. 2006 L1PA L1PA4 18.0 Table 1in Khan et al. 2006 L1PA L1PA5 20.4 Table 1 in Khan et al. 2006 L1PAL1PA6 26.8 Table 1 in Khan et al. 2006 L1PA L1PA7 31.4 Table 1 in Khanet al. 2006 L1PA L1PA8 40.9 Table 1 in Khan et al. 2006 L1PA L1PA8A 41.7Table 1 in Khan et al. 2006 L1PA L1PA10 46.4 Table 1 in Khan et al. 2006L1PA L1PA11 53.3 Table 1 in Khan et al. 2006 L1PA L1PA13B 59.8 Table 1in Khan et al. 2006 L1PA L1PA12 59.7 Table 1 in Khan et al. 2006 L1PAL1PA13A 59.9 Table 1 in Khan et al. 2006 L1PA L1PA14 60.6 Table 1 inKhan et al. 2006 L1PA L1PA15 70.5 Table 1 in Khan et al. 2006 L1PAL1PA16 79.7 Table 1 in Khan et al. 2006 L1PA L1PA17 101.1 Table 1 inKhan et al. 2006 L1PB L1PB1 46.7 Table 1 in Khan et al. 2006 L1PB L1PB258.2 Table 1 in Khan et al. 2006 L1PB L1PB3 73.5 Table 1 in Khan et al.2006 L1PB L1PB4 96.0 Table 1 in Khan et al. 2006 L1MA L1MA1 61.6 Table 1in Khan et al. 2006 L1MA L1MA2 65.8 Table 1 in Khan et al. 2006 L1MAL1MA3 68.1 Table 1 in Khan et al. 2006 L1MA L1MA4 102.3 Table 1 in Khanet al. 2006 L1MA L1MA5 98.6 Table 1 in Khan et al. 2006

In some cases, L1PA3 elements are also highly represented. Inconclusion, primers used in the published for the amplification ofLine-1 biomarkers are not designed optimally, and do not samplespecifically any chosen L1 subfamily, but rather a mixture ofsubfamilies. A consequence of the sub-optimal design of all of theprimer-pairs reported in the literature is that the Line-1 sequencesbeing sampled to generate DNA methylation metrics are not those genomicsequences that contain the most useful information related to the onsetof dysplasia and cancer.

iii. Generation of Subsets of Genomic Repetitive Element Sequences thatare Useful for Distinguishing Tumors from Adjacent Nontumor Tissue, andfrom Healthy Normal Tissue

A list of DNA methylation values calculated as the average methylationof each category or sub-category of repetitive element was generated,including reprotransposon-derived elements, and DNA-transposon-deriveelements. The values are obtained for individual experiments, and eachaverage is generated my multiple probes of the same category, where eachcategory will comprise anywhere from 20 to 48,000 probes. The data forindividual members of each individual family was then analyzed. As anexample of this analysis, the plot shown in FIG. 1 represents the DNAmethylation levels for subclasses of Line1 elements present in mammals.The order the sub-categories is constant in all three of the subsectionsin the plot. It was established based on the extent of variation in theplotted distributions using Shannon entropy information content metric.Only Normal and Tumor experiments were used to calculate the Shannon'sInformation metric.

The arrows point to DNA methylation values calculated by taking thefractional values obtained from Table 1, and calculating a weighedaverage that takes into account the fractional composition, as well asthe DNA methylation value of each class represented in the mixture. The“in-silico PCR” values represent the simulated prediction of the DNAmethylation metrics that would be obtained if one were to perform a PCRexperiment based on the use of published primer sequences, and utilizingas biological material the DNA obtained from the samples of cancer ofthe head and neck. It is notable that none of the DNA methylation valuesindicated by the arrow represents metrics with optimal informationcontent.

Among the publications cited as examples of papers teaching the use ofLine-1 primers as cancer biomarkers, the most recent (Choi et al, 2009,using Line-1 primers designed by Woloszynska-Read et al., 2008) pointout the observation that “5-mdC level in leukocyte DNA was significantlylower in breast cancer cases than healthy controls (p=0.001), but nosignificant case-control differences were observed with LINE-1methylation”. It is not surprising that Choi et al. did not observesignificant case-control differences, in the light of the data presentedherein (see FIG. 1) that the Woloszynska-Read primer set generates PCRamplicons with relatively low information contend with regards todysplasia or cancer. The data presented herein show the subfamilies withthe largest information content are L1PA4, L1PA3, and L1PA12, none ofwhich have been reported in the literature as candidate cancerbiomarkers.

iv. Statistical Analysis of Optimal Repetitive DNA Biomarkers Selectedfrom a Large Set of Repetitive Elements that Suffer DNA MethylationChanges in Dysplasia and Cancer.

A list of repetitive DNA subfamilies that comprises approximately 900members was generated. A list of DNA methylation values calculated asthe average methylation of each category or sub-category of repetitiveelement was generated, including reprotransposon-derived elements, andDNA-transposon-derive elements. The values are obtained for individualexperiments, and each average is generated my multiple probes of thesame category. Two independent algorithms were used to rank thevariables based on their abilities to classify experiments. Wilcoxon wasused to classify tumor and non-tumor adjacent. Random Forest was used toclassify Normal, Non-Tumor Adjacent and Tumor experiments. Bothalgorithms relied on the same definition of variables. The variablesincluded single probes, or collections of probes sharing a commonfeature i.e. proximity to the repetitive element. Both algorithms rankedthe variables based on repetitive-elements and non-genic, non-repetitiveprobes very high. Moreover, the repetitive element categories appear tobe better classifiers than the gene probes as evidenced by theenrichment of repetitive element categories in the top rankedcategories. Specifically, in top 30 categories there were 7 gene probes(out of ˜44,000), and 14 repetitive element categories (out of a totalof 896) (FIG. 2).

The Wilcoxon test results, where the biomarker is ranked based onWilcoxon test p-value for the top 200 variables out of 138,783(repetitive elements, genes, non-genic, non-repetitive) are shown inTable 3. The Wilcoxon test results for the top 200 out of 90,007non-repetitive non-gene probes are shown in Table 4. The Wilcoxon testresults for all repetitive categories and literature-based categories(898) are shown in Table 5.

TABLE 3 Top 200 variables out of 138,783 (repetitive elements, genes,non-genic, non-repetitive) ordered by a Wilcoxon p-value. The list isordered by a Wilcoxon p-value (pval) indicating how informative acategory is to distinguish Tumor and Non-Tumor- Adjacent experiments.Rank column shows a relative position of a category in the list, K is aninternal DB id of a category, count shows how many probes are includedin the category. A short description of a category indicates whether aprobe is near a gene, or in a non- repetitive part of the genome. Forrepetitive elements the description includes the information aboutrepeat name, class and family as well as the number of repeats in thegenome and mean length. P-value was calculated using Wilcoxonnon-parametric, non-paired test. rank K count description pval 1K.nonrep.122208 1 K.nonrep.122208 4.55E−12 2 K.nonrep.102186 1K.nonrep.102186 1.06E−09 3 K.nonrep.122209 1 K.nonrep.122209 1.31E−09 4K.repcat.e&g.2008.body.300.M

91 MLT2B2.ERVL.LTR.2019.[335] 1.99E−09 5 K.gene.122207 1 K.gene.1222073.65E−09 6 K.repcat.e&g.2008.body.300.E

6129 ERVL.ERVL.LTR.826.[422] 5.37E−09 7 K.nonrep.122204 1K.nonrep.122204 6.49E−09 8 K.gene.270555 1 K.gene.270555 1.13E−08 9K.repcat.e&g.2008.body.300.M

15574 MaLR 1.61E−08 10 K.nonrep.258987 1 K.nonrep.258987 1.61E−08 11K.repcat.e&g.2008.body.300.L

38991 LTR 1.92E−08 12 K.repcat.e&g.2008.body.300.M

239 MLT1E2.MaLR.LTR.3960.[377] 1.92E−08 13 K.gene.152861 1 K.gene.1528611.92E−08 14 K.gene.50699 1 K.gene.50699 1.92E−08 15 K.nonrep.147761 1K.nonrep.147761 1.92E−08 16 K.gene.152859 1 K.gene.152859 2.28E−08 17K.nonrep.147762 1 K.nonrep.147762 2.28E−08 18 K.nonrep.149154 1K.nonrep.149154 2.28E−08 19 K.repcat.e.2008.body.300.MLT

420 MLT1A.MaLR.LTR.8650.[280] 2.71E−08 20 K.gene.269730 1 K.gene.2697302.71E−08 21 K.nonrep.19670 1 K.nonrep.19670 2.71E−08 22K.repcat.e.2008.body.300.MLT

131 MLT2B3.ERVL.LTR.2966.[406] 3.21E−08 23 K.nonrep.296142 1K.nonrep.296142 3.79E−08 24 K.gene.298679 1 K.gene.298679 5.25E−08 25K.gene.334064 1 K.gene.334064 5.25E−08 26 K.nonrep.122203 1K.nonrep.122203 6.17E−08 27 K.repcat.e&g.2008.body.300.H

28 HUERS-P3b.ERV1.LTR.378.[917] 7.24E−08 28 K.gene.223221 1K.gene.223221 7.24E−08 29 K.nonrep.113501 1 K.nonrep.113501 8.47E−08 30K.gene.122206 1 K.gene.122206 9.90E−08 31 K.gene.167356 1 K.gene.1673569.90E−08 32 K.gene.228738 1 K.gene.228738 9.90E−08 33 K.nonrep.311545 1K.nonrep.311545 9.90E−08 34 K.repcat.e.2008.body.300.MER

101 MER50B.ERV1.LTR.681.[468] 1.15E−07 35 K.repcat.e.2008.body.300.MLT

236 MLT1G1.MaLR.LTR.4437.[320] 1.15E−07 36 K.nonrep.153897 1K.nonrep.153897 1.15E−07 37 K.repcat.e&g.2008.body.300.M

348 MADE1.Mariner.DNA.7773.[61] 1.34E−07 38 K.repcat.e.2008.body.300.MER

216 MER39.ERV1.LTR.3125.[336] 1.34E−07 39 K.standard.L1P.special 740special 1.34E−07 40 K.gene.209707 1 K.gene.209707 1.34E−07 41K.gene.34722 1 K.gene.34722 1.34E−07 42 K.gene.84633 1 K gene.846331.34E−07 43 K.gene.87798 1 K.gene.87798 1.34E−07 44 K.nonrep.227488 1K.nonrep.227488 1.34E−07 45 K.nonrep.70135 1 K.nonrep.70135 1.34E−07 46K.repcat.e&g.2008.body.300.M

169 MLT2B1.ERVL.LTR.4186.[325] 1.56E−07 47 K.repcat.e.2008.body.300.MLT

1018 MLT1A0.MaLR.LTR.20156.[279] 1.56E−07 48 K.gene.38080 1 K.gene.380801.56E−07 49 K.repcat.e.2008.body.300.MST

199 MSTC.MaLR.LTR.3115.[284] 1.81E−07 50 K.gene.122205 1 K.gene.1222051.81E−07 51 K.gene.138996 1 K.gene.138996 1.81E−07 52 K.nonrep.154468 1K.nonrep.154468 1.81E−07 53 K.gene.50700 1 K.gene.50700 2.10E−07 54K.nonrep.169335 1 K.nonrep.169335 2.10E−07 55 K.nonrep.38935 1K.nonrep.38935 2.43E−07 56 K.repcat.e&g.2008.body.300.A

997 AcHobo 2.81E−07 57 K.repcat.e.2008.body.300.MER

46 MER66C.ERV1.LTR.661.[279] 2.81E−07 58 K.gene.170821 1 K.gene.1708212.81E−07 59 K.gene.248792 1 K.gene.248792 2.81E−07 60 K.gene.57291 1K.gene.57291 2.81E−07 61 K.gene.6904 1 K.gene.6904 2.81E−07 62K.gene.77200 1 K.gene.77200 2.81E−07 63 K.gene.89746 1 K.gene.897462.81E−07 64 K.gene.99966 1 K.gene.99966 2.81E−07 65 K.nonrep.169334 1K.nonrep.169334 2.81E−07 66 K.nonrep.230392 1 K.nonrep.230392 2.81E−0767 K.nonrep.70785 1 K.nonrep.70785 3.24E−07 68K.repcat.e&g.2008.body.300.L

53 LTR54B.ERV1.LTR.832.[289] 3.74E−07 69 K.gene.232742 1 K.gene.2327423.74E−07 70 K.gene.81226 1 K.gene.81226 3.74E−07 71 K.nonrep.101592 1K.nonrep.101592 3.74E−07 72 K.nonrep.266307 1 K.nonrep.266307 3.74E−0773 K.repcat.e&g.2008.body.300.M

49 MER67D.ERV1.LTR.1130.[294] 4.30E−07 74 K.repcat.e&g.2008.body.300.M

174 MLT2D.ERVL.LTR.4035.[266] 4.30E−07 75 K.repcat.e.2008.body.300.MLT

136 MLT1E.MaLR.LTR.3378.[359] 4.30E−07 76 K.repcat.e.2008.body.300.MLT

506 MLT1I.MaLR.LTR.11191.[218] 4.30E−07 77 K.gene.147633 1 K.gene.1476334.30E−07 78 K.gene.153333 1 K.gene.153333 4.30E−07 79 K.gene.223222 1K.gene.223222 4.30E−07 80 K.gene.226262 1 K.gene.226262 4.30E−07 81K.gene.301073 1 K.gene.301073 4.30E−07 82 K.gene.303432 1 K.gene.3034324.30E−07 83 K.nonrep.154467 1 K.nonrep.154467 4.30E−07 84K.nonrep.274801 1 K.nonrep.274801 4.30E−07 85 K.nonrep.311662 1K.nonrep.311662 4.30E−07 86 K.nonrep.53469 1 K.nonrep.53469 4.30E−07 87K.repcat.e&g.2008.body.300.T

306 Tigger3 (Golem).MER2 type.DNA

4.94E−07 88 K.repcat.e.2008.body.300.THE

693 THE1B.MaLR.LTR.22106.[329] 4.94E−07 89 K.gene.167548 1 K.gene.1675484.94E−07 90 K.gene.285109 1 K.gene.285109 4.94E−07 91 K.nonrep.69552 1K.nonrep.69552 4.94E−07 92 K.gene.27403 1 K.gene.27403 5.67E−07 93K.gene.301951 1 K.gene.301951 5.67E−07 94 K.nonrep.266864 1K.nonrep.266864 5.67E−07 95 K.repcat.e&g.2008.body.300.M

127 MER63A.AcHobo.DNA.2791.[184] 6.50E−07 96K.repcat.e.2008.body.300.MLT

219 MLT1F2.MaLR.LTR.4152.[353] 6.50E−07 97 K.gene.102175 1 K.gene.1021756.50E−07 98 K.gene.151208 1 K.gene.151208 6.50E−07 99 K.gene.174556 1K.gene.174556 6.50E−07 100 K.gene.303208 1 K.gene.303208 6.50E−07 101K.nonrep.266780 1 K.nonrep.266780 6.50E−07 102 K.repcat.e&g.2008body.300.L

329 L1PB4.L1.LINE.6330.[529] 7.44E−07 103 K.repcat.e&g.2008.body.300.L

10 LSAU.Satellite.Satellite.41.

7.44E−07 104 K.repcat.e.2008.body.300.MLT

199 MLT1F1.MaLR.LTR.3489.[292] 7.44E−07 105 K.gene.296128 1K.gene.296128 7.44E−07 106 K.gene.31409 1 K.gene.31409 7.44E−07 107K.gene.54663 1 K.gene.54663 7.44E−07 108 K.gene.83279 1 K.gene.832797.44E−07 109 K.repcat.e.2008.body.300.ERV

132 ERVL-B4.ERVL.LTR.2984.[564] 8.51E−07 110K.repcat.e.2008.body.300.MER

80 MER6.MER2 type.DNA.926.[418] 8.51E−07 111K.repcat.e.2008.body.300.MER

82 MER61A.ERV1.LTR.791.[303] 8.51E−07 112 K.gene.115654 1 K.gene.1156548.51E−07 113 K.gene.133995 1 K.gene.133995 8.51E−07 114 K.gene.191733 1K.gene.191733 8.51E−07 115 K.gene.192817 1 K.gene.192817 8.51E−07 116K.gene.203055 1 K.gene.203055 8.51E−07 117 K.gene.219208 1 K.gene.2192088.51E−07 118 K.gene.227873 1 K.gene.227873 8.51E−07 119 K.gene.315989 1K.gene.315989 8.51E−07 120 K.gene.54860 1 K.gene.54860 8.51E−07 121K.gene.61805 1 K.gene.61805 8.51E−07 122 K.gene.63060 1 K.gene.630608.51E−07 123 K.nonrep.15878 1 K.nonrep.15878 8.51E−07 124 K.nonrep.74631 K.nonrep.7463 8.51E−07 125 K.nonrep.90539 1 K.nonrep.90539 8.51E−07126 K.repcat.e.2008.body.300.MLT

307 MLT1A1.MaLR.LTR.6611.[294] 9.71E−07 127 K.gene.152252 1K.gene.152252 9.71E−07 128 K.gene.182820 1 K.gene.182820 9.71E−07 129K.gene.232740 1 K.gene.232740 9.71E−07 130 K.nonrep.211225 1K.nonrep.211225 9.71E−07 131 K.repcat.e&g.2008.body.300.L

881 L1MC3.L1.LINE.12792.[547] 1.11E−06 132 K.gene.174505 1 K.gene.1745051.11E−06 133 K.gene.252637 1 K.gene.252637 1.11E−06 134 K.gene.268533 1K.gene.268533 1.11E−06 135 K.gene.295375 1 K.gene.295375 1.11E−06 136K.gene.61963 1 K.gene.61963 1.11E−06 137 K.nonrep.128685 1K.nonrep.128685 1.11E−06 138 K.nonrep.266306 1 K.nonrep.266306 1.11E−06139 K.nonrep.295372 1 K.nonrep.295372 1.11E−06 140 K.gene.102177 1K.gene.102177 1.26E−06 141 K.gene.111133 1 K.gene.111133 1.26E−06 142K.gene.174541 1 K.gene.174541 1.26E−06 143 K.gene.328463 1 K.gene.3284631.26E−06 144 K.gene.99987 1 K.gene.99987 1.26E−06 145 K.nonrep.110206 1K.nonrep.110206 1.26E−06 146 K.nonrep.14883 1 K.nonrep.14883 1.26E−06147 K.nonrep.163948 1 K.nonrep.163948 1.26E−06 148 K.nonrep.180551 1K.nonrep.180551 1.26E−06 149 K.nonrep.211798 1 K.nonrep.211798 1.26E−06150 K.repcat.e&g.2008.body.300.M

855 Mariner 1.43E−06 151 K.repcat.e.2008.body.300. ERV

33 ERV 1.43E−06 152 K.gene.130982 1 K.gene.130982 1.43E−06 153K.gene.319750 1 K.gene.319750 1.43E−06 154 K.gene.38011 1 K.gene.380111.43E−06 155 K.gene.41734 1 K.gene.41734 1.43E−06 156 K.gene.74207 1K.gene.74207 1.43E−06 157 K.gene.85137 1 K.gene.85137 1.43E−06 158K.nonrep.151268 1 K.nonrep.151268 1.43E−06 159 K.nonrep.168488 1K.nonrep.168488 1.43E−06 160 K.nonrep.229863 1 K.nonrep.229863 1.43E−06161 K.nonrep.278715 1 K.nonrep.278715 1.43E−06 162 K.nonrep.69598 1K.nonrep.69598 1.43E−06 163 K.nonrep.96781 1 K.nonrep.96781 1.43E−06 164K.repcat.e&g.2008.body.300.L

15 LTR22A.ERVK.LTR.187.[402] 1.63E−06 165 K.gene.132656 1 K.gene.1326561.63E−06 166 K.gene.237832 1 K.gene.237832 1.63E−06 167 K.gene.261415 1K.gene.261415 1.63E−06 168 K.gene.265132 1 K.gene.265132 1.63E−06 169K.gene.271240 1 K.gene.271240 1.63E−06 170 K.gene.296981 1 K.gene.2969811.63E−06 171 K.gene.327487 1 K.gene.327487 1.63E−06 172 K.nonrep.2603551 K.nonrep.260355 1.63E−06 173 K.nonrep.308324 1 K.nonrep.3083241.63E−06 174 K.nonrep.83323 1 K.nonrep.83323 1.63E−06 175 K.nonrep.833241 K.nonrep.83324 1.63E−06 176 K.repcat.e&g.2008.body.300.L

108 LTR40a.ERVL.LTR.2060.[328] 1.85E−06 177 K.gene.165048 1K.gene.165048 1.85E−06 178 K.gene.183908 1 K.gene.183908 1.85E−06 179K.gene.76851 1 K.gene.76851 1.85E−06 180 K.nonrep.100314 1K.nonrep.100314 1.85E−06 181 K.nonrep.14898 1 K.nonrep.14898 1.85E−06182 K.nonrep.162733 1 K.nonrep.162733 1.85E−06 183 K.nonrep.229975 1K.nonrep.229975 1.85E−06 184 K.nonrep.232745 1 K.nonrep.232745 1.85E−06185 K.nonrep.264903 1 K.nonrep.264903 1.85E−06 186 K.nonrep.303433 1K.nonrep.303433 1.85E−06 187 K.nonrep.69336 1 K.nonrep.69336 1.85E−06188 K.nonrep.86313 1 K.nonrep.86313 1.85E−06 189K.repcat.e&g.2008.body.300.L

383 L1MA7.L1.LINE.7550.[459] 2.10E−06 190 K.repcat.e.2008.body.300.MER

217 MER41A-ERV1-LTR-2479.[384] 2.10E−06 191 K.gene.123586 1K.gene.123586 2.10E−06 192 K.gene.146588 1 K.gene.146588 2.10E−06 193K.gene.31528 1 K.gene.31528 2.10E−06 194 K.gene.330104 1 K.gene.3301042.10E−06 195 K.gene.43145 1 K.gene.43145 2.10E−06 196 K.gene.51985 1K.gene.51985 2.10E−06 197 K.nonrep.149152 1 K.nonrep.149152 2.10E−06 198K.nonrep.221153 1 K.nonrep.221153 2.10E−06 199 K.nonrep.265143 1K.nonrep.265143 2.10E−06 200 K.nonrep.309324 1 K.nonrep.309324 2.10E−06

indicates data missing or illegible when filed

TABLE 4 Top 200 out of 90,007 non-repetitive non-gene probes rankedbased on non-paired Wilcoxon test. Based on non-paired Wilcoxon test.these best differentiate Tumor from Non-Tumor Adjacent experiments. Kand description indicate internal probe id of the category, countindicates that the category is a single probe. rank K count descriptionpval 1 K.nonrep.122208 1 K.nonrep.122208 4.55E−12 2 K.nonrep.102186 1K.nonrep.102186 1.06E−09 3 K.nonrep.122209 1 K.nonrep.122209 1.31E−09 4K.nonrep.122204 1 K.nonrep.122204 6.49E−09 5 K.nonrep.258987 1K.nonrep.258987 1.61E−08 6 K.nonrep.147761 1 K.nonrep.147761 1.92E−08 7K.nonrep.147762 1 K.nonrep.147762 2.28E−08 8 K.nonrep.149154 1K.nonrep.149154 2.28E−08 9 K.nonrep.19670 1 K.nonrep.19670 2.71E−08 10K.nonrep.296142 1 K.nonrep.296142 3.79E−08 11 K.nonrep.122203 1K.nonrep.122203 6.17E−08 12 K.nonrep.113501 1 K.nonrep.113501 8.47E−0813 K.nonrep.311545 1 K.nonrep.311545 9.90E−08 14 K.nonrep.153897 1K.nonrep.153897 1.15E−07 15 K.nonrep.227488 1 K.nonrep.227488 1.34E−0716 K.nonrep.70135 1 K.nonrep.70135 1.34E−07 17 K.nonrep.154468 1K.nonrep.154468 1.81E−07 18 K.nonrep.169335 1 K.nonrep.169335 2.10E−0719 K.nonrep.38935 1 K.nonrep.38935 2.43E−07 20 K.nonrep.169334 1K.nonrep.169334 2.81E−07 21 K.nonrep.230392 1 K.nonrep.230392 2.81E−0722 K.nonrep.70785 1 K.nonrep.70785 3.24E−07 23 K.nonrep.101592 1K.nonrep.101592 3.74E−07 24 K.nonrep.266307 1 K.nonrep.266307 3.74E−0725 K.nonrep.154467 1 K.nonrep.154467 4.30E−07 26 K.nonrep.274801 1K.nonrep.274801 4.30E−07 27 K.nonrep.311662 1 K.nonrep.311662 4.30E−0728 K.nonrep.53469 1 K.nonrep.53469 4.30E−07 29 K.nonrep.69552 1K.nonrep.69552 4.94E−07 30 K.nonrep.266864 1 K.nonrep.266864 5.67E−07 31K.nonrep.266780 1 K.nonrep.266780 6.50E−07 32 K.nonrep.15878 1K.nonrep.15878 8.51E−07 33 K.nonrep.7463 1 K.nonrep.7463 8.51E−07 34K.nonrep.90539 1 K.nonrep.90539 8.51E−07 35 K.nonrep.211225 1K.nonrep.211225 9.71E−07 36 K.nonrep.128685 1 K.nonrep.128685 1.11E−0637 K.nonrep.266306 1 K.nonrep.266306 1.11E−06 38 K.nonrep.295372 1K.nonrep.295372 1.11E−06 39 K.nonrep.110206 1 K.nonrep.110206 1.26E−0640 K.nonrep.14883 1 K.nonrep.14883 1.26E−06 41 K.nonrep.163948 1K.nonrep.163948 1.26E−06 42 K.nonrep.180551 1 K.nonrep.180551 1.26E−0643 K.nonrep.211798 1 K.nonrep.211798 1.26E−06 44 K.nonrep.151268 1K.nonrep.151268 1.43E−06 45 K.nonrep.168488 1 K.nonrep.168488 1.43E−0646 K.nonrep.229863 1 K.nonrep.229863 1.43E−06 47 K.nonrep.278715 1K.nonrep.278715 1.43E−06 48 K.nonrep.69598 1 K.nonrep.69598 1.43E−06 49K.nonrep.96781 1 K.nonrep.96781 1.43E−06 50 K.nonrep.260355 1K.nonrep.260355 1.63E−06 51 K.nonrep.308324 1 K.nonrep.308324 1.63E−0652 K.nonrep.83323 1 K.nonrep.83323 1.63E−06 53 K.nonrep.83324 1K.nonrep.83324 1.63E−06 54 K.nonrep.100314 1 K.nonrep.100314 1.85E−06 55K.nonrep.14898 1 K.nonrep.14898 1.85E−06 56 K.nonrep.162733 1K.nonrep.162733 1.85E−06 57 K.nonrep.229975 1 K.nonrep.229975 1.85E−0658 K.nonrep.232745 1 K.nonrep.232745 1.85E−06 59 K.nonrep.264903 1K.nonrep.264903 1.85E−06 60 K.nonrep.303433 1 K.nonrep.303433 1.85E−0661 K.nonrep.69336 1 K.nonrep.69336 1.85E−06 62 K.nonrep.86313 1K.nonrep.86313 1.85E−06 63 K.nonrep.149152 1 K.nonrep.149152 2.10E−06 64K.nonrep.221153 1 K.nonrep.221153 2.10E−06 65 K.nonrep.265143 1K.nonrep.265143 2.10E−06 66 K.nonrep.309324 1 K.nonrep.309324 2.10E−0667 K.nonrep.325327 1 K.nonrep.325327 2.10E−06 68 K.nonrep.83736 1K.nonrep.83736 2.10E−06 69 K.nonrep.142003 1 K.nonrep.142003 2.38E−06 70K.nonrep.149147 1 K.nonrep.149147 2.38E−06 71 K.nonrep.153222 1K.nonrep.153222 2.38E−06 72 K.nonrep.236021 1 K.nonrep.236021 2.38E−0673 K.nonrep.301887 1 K.nonrep.301887 2.38E−06 74 K.nonrep.313414 1K.nonrep.313414 2.38E−06 75 K.nonrep.39461 1 K.nonrep.39461 2.38E−06 76K.nonrep.168356 1 K.nonrep.168356 2.69E−06 77 K.nonrep.266868 1K.nonrep.266868 2.69E−06 78 K.nonrep.298283 1 K.nonrep.298283 2.69E−0679 K.nonrep.306097 1 K.nonrep.306097 2.69E−06 80 K.nonrep.33133 1K.nonrep.33133 2.69E−06 81 K.nonrep.155005 1 K.nonrep.155005 3.04E−06 82K.nonrep.191208 1 K.nonrep.191208 3.04E−06 83 K.nonrep.192962 1K.nonrep.192962 3.04E−06 84 K.nonrep.280039 1 K.nonrep.280039 3.04E−0685 K.nonrep.324931 1 K.nonrep.324931 3.04E−06 86 K.nonrep.36461 1K.nonrep.36461 3.04E−06 87 K.nonrep.89681 1 K.nonrep.89681 3.04E−06 88K.nonrep.91291 1 K.nonrep.91291 3.04E−06 89 K.nonrep.263088 1K.nonrep.263088 3.43E−06 90 K.nonrep.285373 1 K.nonrep.285373 3.43E−0691 K.nonrep.311342 1 K.nonrep.311342 3.43E−06 92 K.nonrep.1529 1K.nonrep.1529 3.86E−06 93 K.nonrep.204771 1 K.nonrep.204771 3.86E−06 94K.nonrep.230495 1 K.nonrep.230495 3.86E−06 95 K.nonrep.236959 1K.nonrep.236959 3.86E−06 96 K.nonrep.261527 1 K.nonrep.261527 3.86E−0697 K.nonrep.287123 1 K.nonrep.287123 3.86E−06 98 K.nonrep.328189 1K.nonrep.328189 3.86E−06 99 K.nonrep.48142 1 K.nonrep.48142 3.86E−06 100K.nonrep.109912 1 K.nonrep.109912 4.35E−06 101 K.nonrep.257391 1K.nonrep.257391 4.35E−06 102 K.nonrep.281594 1 K.nonrep.281594 4.35E−06103 K.nonrep.333017 1 K.nonrep.333017 4.35E−06 104 K.nonrep.34127 1K.nonrep.34127 4.35E−06 105 K.nonrep.77018 1 K.nonrep.77018 4.35E−06 106K.nonrep.149145 1 K.nonrep.149145 4.90E−06 107 K.nonrep.266856 1K.nonrep.266856 4.90E−06 108 K.nonrep.312743 1 K.nonrep.312743 4.90E−06109 K.nonrep.39460 1 K.nonrep.39460 4.90E−06 110 K.nonrep.55415 1K.nonrep.55415 4.90E−06 111 K.nonrep.146703 1 K.nonrep.146703 5.51E−06112 K.nonrep.166836 1 K.nonrep.166836 5.51E−06 113 K.nonrep.246999 1K.nonrep.246999 5.51E−06 114 K.nonrep.32387 1 K.nonrep.32387 5.51E−06115 K.nonrep.106801 1 K.nonrep.106801 6.18E−06 116 K.nonrep.112953 1K.nonrep.112953 6.18E−06 117 K.nonrep.132542 1 K.nonrep.132542 6.18E−06118 K.nonrep.138529 1 K.nonrep.138529 6.18E−06 119 K.nonrep.215454 1K.nonrep.215454 6.18E−06 120 K.nonrep.217442 1 K.nonrep.217442 6.18E−06121 K.nonrep.311326 1 K.nonrep.311326 6.18E−06 122 K.nonrep.315151 1K.nonrep.315151 6.18E−06 123 K.nonrep.7464 1 K.nonrep.7464 6.18E−06 124K.nonrep.8093 1 K.nonrep.8093 6.18E−06 125 K.nonrep.84002 1K.nonrep.84002 6.18E−06 126 K.nonrep.91292 1 K.nonrep.91292 6.18E−06 127K.nonrep.151013 1 K.nonrep.151013 6.94E−06 128 K.nonrep.180717 1K.nonrep.180717 6.94E−06 129 K.nonrep.277169 1 K.nonrep.277169 6.94E−06130 K.nonrep.37999 1 K.nonrep.37999 6.94E−06 131 K.nonrep.39495 1K.nonrep.39495 6.94E−06 132 K.nonrep.61818 1 K.nonrep.61818 6.94E−06 133K.nonrep.141416 1 K.nonrep.141416 7.78E−06 134 K.nonrep.141421 1K.nonrep.141421 7.78E−06 135 K.nonrep.232140 1 K.nonrep.232140 7.78E−06136 K.nonrep.247791 1 K.nonrep.247791 7.78E−06 137 K.nonrep.270015 1K.nonrep.270015 7.78E−06 138 K.nonrep.296136 1 K.nonrep.296136 7.78E−06139 K.nonrep.47698 1 K.nonrep.47698 7.78E−06 140 K.nonrep.98720 1K.nonrep.98720 7.78E−06 141 K.nonrep.118789 1 K.nonrep.118789 8.71E−06142 K.nonrep.145698 1 K.nonrep.145698 8.71E−06 143 K.nonrep.149151 1K.nonrep.149151 8.71E−06 144 K.nonrep.153898 1 K.nonrep.153898 8.71E−06145 K.nonrep.16216 1 K.nonrep.16216 8.71E−06 146 K.nonrep.250409 1K.nonrep.250409 8.71E−06 147 K.nonrep.40381 1 K.nonrep.40381 8.71E−06148 K.nonrep.134741 1 K.nonrep.134741 9.75E−06 149 K.nonrep.18185 1K.nonrep.18185 9.75E−06 150 K.nonrep.211226 1 K.nonrep.211226 9.75E−06151 K.nonrep.241555 1 K.nonrep.241555 9.75E−06 152 K.nonrep.246998 1K.nonrep.246998 9.75E−06 153 K.nonrep.259070 1 K.nonrep.259070 9.75E−06154 K.nonrep.262108 1 K.nonrep.262108 9.75E−06 155 K.nonrep.2880 1K.nonrep.2880 9.75E−06 156 K.nonrep.314550 1 K.nonrep.314550 9.75E−06157 K.nonrep.39202 1 K.nonrep.39202 9.75E−06 158 K.nonrep.102180 1K.nonrep.102180 1.09E−05 159 K.nonrep.10262 1 K.nonrep.10262 1.09E−05160 K.nonrep.103372 1 K.nonrep.103372 1.09E−05 161 K.nonrep.122219 1K.nonrep.122219 1.09E−05 162 K.nonrep.192867 1 K.nonrep.192867 1.09E−05163 K.nonrep.19642 1 K.nonrep.19642 1.09E−05 164 K.nonrep.26381 1K.nonrep.26381 1.09E−05 165 K.nonrep.293297 1 K.nonrep.293297 1.09E−05166 K.nonrep.312607 1 K.nonrep.312607 1.09E−05 167 K.nonrep.335925 1K.nonrep.335925 1.09E−05 168 K.nonrep.38023 1 K.nonrep.38023 1.09E−05169 K.nonrep.39395 1 K.nonrep.39395 1.09E−05 170 K.nonrep.60573 1K.nonrep.60573 1.09E−05 171 K.nonrep.76028 1 K.nonrep.76028 1.09E−05 172K.nonrep.77318 1 K.nonrep.77318 1.09E−05 173 K.nonrep.81488 1K.nonrep.81488 1.09E−05 174 K.nonrep.82426 1 K.nonrep.82426 1.09E−05 175K.nonrep.95015 1 K.nonrep.95015 1.09E−05 176 K.nonrep.98975 1K.nonrep.98975 1.09E−05 177 K.nonrep.140999 1 K.nonrep.140999 1.22E−05178 K.nonrep.175663 1 K.nonrep.175663 1.22E−05 179 K.nonrep.181213 1K.nonrep.181213 1.22E−05 180 K.nonrep.192866 1 K.nonrep.192866 1.22E−05181 K.nonrep.206705 1 K.nonrep.206705 1.22E−05 182 K.nonrep.291293 1K.nonrep.291293 1.22E−05 183 K.nonrep.295083 1 K.nonrep.295083 1.22E−05184 K.nonrep.311413 1 K.nonrep.311413 1.22E−05 185 K.nonrep.326403 1K.nonrep.326403 1.22E−05 186 K.nonrep.333741 1 K.nonrep.333741 1.22E−05187 K.nonrep.39359 1 K.nonrep.39359 1.22E−05 188 K.nonrep.45035 1K.nonrep.45035 1.22E−05 189 K.nonrep.45700 1 K.nonrep.45700 1.22E−05 190K.nonrep.51929 1 K.nonrep.51929 1.22E−05 191 K.nonrep.148110 1K.nonrep.148110 1.36E−05 192 K.nonrep.195743 1 K.nonrep.195743 1.36E−05193 K.nonrep.234061 1 K.nonrep.234061 1.36E−05 194 K.nonrep.292140 1K.nonrep.292140 1.36E−05 195 K.nonrep.31569 1 K.nonrep.31569 1.36E−05196 K.nonrep.318682 1 K.nonrep.318682 1.36E−05 197 K.nonrep.327365 1K.nonrep.327365 1.36E−05 198 K.nonrep.328190 1 K.nonrep.328190 1.36E−05199 K.nonrep.328628 1 K.nonrep.328628 1.36E−05 200 K.nonrep.54350 1K.nonrep.54350 1.36E−05

TABLE 5 All repetitive categories and literature-based categories (898)ranked based on Wilcoxon test p-value. All 898 repetitive categoriesranked based on Wilcoxon test pvalue (pval) indicating how well a givencategory differentiates between Tumor and Non- Tumor adjacentexperiments. Description of a category provides information about repeatname, class and family (based on RepBase and RepeatMasker) as well as anumber of elements in the genome and their [average length]. The numberof probes used to create this category is indicated in column count. Theprobes are found within the body of the repetitive element +/−300 bases.rank K count description pval 1 K.repcat.e&g.2008.body.300.M

91 MLT2B2.ERVL.LTR.2019.[335] 1.99E−09 2 K.repcat.e&g.2008.body.300.E

6129 ERVL.ERVL.LTR.826.[422] 5.37E−09 3 K.repcat.e&g.2008.body.300.M

15574 MaLR 1.61E−08 4 K.repcat.e&g.2008.body.300.L

38991 LTR 1.92E−08 5 K.repcat.e&g.2008.body.300.M

239 MLT1E2.MaLR.LTR.3960.[377] 1.92E−08 6 K.repcat.e.2008.body.300.MLT

420 MLT1A.MaLR.LTR.8650.[280] 2.71E−08 7 K.repcat.e.2008.body.300.MLT

131 MLT2B3.ERVL.LTR.2966.[406] 3.21E−08 8 K.repcat.e&g.2008.body.300.H

28 HUERS-P3b.ERV1.LTR.378.[917] 7.24E−08 9 K.repcat.e.2008.body.300.MER

101 MER50B.ERV1.LTR.681.[468] 1.15E−07 10 K.repcat.e.2008.body.300.MLT

236 MLT1G1.MaLR.LTR.4437.[320] 1.15E−07 11 K.repcat.e&g.2008.body.300.M

348 MADE1.Mariner.DNA.7773.[61] 1.34E−07 12 K.repcat.e.2008.body.300.MER

216 MER39.ERV1.LTR.3125.[336] 1.34E−07 13 K.repcat.e&g.2008.body.300.M

169 MLT2B1.ERVL.LTR.4186.[325] 1.56E−07 14 K.repcat.e.2008.body.300.MLT

1018 MLT1A0.MaLR.LTR.20156.[279] 1.56E−07 15K.repcat.e.2008.body.300.MST

199 MSTC.MaLR.LTR.3115.[284] 1.81E−07 16 K.repcat.e&g.2008.body.300.A

997 AcHobo 2.81E−07 17 K.repcat.e.2008.body.300.MER

46 MER66C.ERV1.LTR.661.[279] 2.81E−07 18 K.repcat.e&g.2008.body.300.L

53 LTR54B.ERV1.LTR.832.[289] 3.74E−07 19 K.repcat.e&g.2008.body.300.M

49 MER67D.ERV1.LTR.1130.[294] 4.30E−07 20 K.repcat.e&g.2008.body.300.M

174 MLT2D.ERVL.LTR.4035.[266] 4.30E−07 21 K.repcat.e.2008.body.300.MLT

136 MLT1E.MaLR.LTR.3378.[359] 4.30E−07 22 K.repcat.e.2008.body.300.MLT

506 MLT1I.MaLR.LTR.11191.[218] 4.30E−07 23 K.repcat.e&g.2008.body.300.T

306 Tigger3(Golem).MER2_type.DNA

4.94E−07 24 K.repcat.e.2008.body.300.THE

693 THE1B.MaLR.LTR.22106.[329] 4.94E−07 25 K.repcat.e&g.2008.body.300.M

127 MER63A.AcHobo.DNA.2791.[184] 6.50E−07 26K.repcat.e.2008.body.300.MLT

219 MLT1F2.MaLR.LTR.4152.[353] 6.50E−07 27 K.repcat.e&g.2008.body.300.L

329 L1PB4.L1.LINE.6330.[529] 7.44E−07 28 K.repcat.e&g.2008.body.300.L

10 LSAU.Satellite.Satellite.41.

7.44E−07 29 K.repcat.e.2008.body.300.MLT

199 MLT1F1.MaLR.LTR.3489.[292] 7.44E−07 30 K.repcat.e.2008.body.300.ERV

132 ERVL-B4.ERVL.LTR.2984.[564] 8.51E−07 31 K.repcat.e.2008.body.300.MER

80 MER6.MER2_type.DNA.926.[418] 8.51E−07 32 K.repcat.e.2008.body.300.MER

82 MER61A.ERV1.LTR.791.[303] 8.51E−07 33 K.repcat.e.2008.body.300.MLT

307 MLT1A1.MaLR.LTR.6611.[294] 9.71E−07 34 K.repcat.e&g.2008.body.300.L

881 L1MC3.L1.LINE.12792.[547] 1.11E−06 35 K.repcat.e&g.2008.body.300.M

855 Mariner 1.43E−06 36 K.repcat.e.2008.body.300.ERV

33 ERV 1.43E−06 37 K.repcat.e&g.2008.body.300.L

15 LTR22A.ERVK.LTR.187.[402] 1.63E−06 38 K.repcat.e&g.2008.body.300.L

108 LTR40a.ERVL.LTR.2060.[328] 1.85E−06 39 K.repcat.e&g.2008.body.300.L

383 L1MA7.L1.LINE.7550.[459] 2.10E−06 40 K.repcat.e.2008.body.300.MER

217 MER41A.ERV1.LTR.2479.[384] 2.10E−06 41 K.repcat.e&g.2008.body.300.C

57 Charlie3.MER1_type.DNA.639.[

2.38E−06 42 K.repcat.e&g.2008.body.300.M

127 MER57A- 2.38E−06 43 K.repcat.e.2008.body.300.HER

185 HERV16.ERVL.LTR.4493.[505] 2.38E−06 44 K.repcat.e.2008.body.300.MER

108 MER4D.ERV1.LTR.1275.[421] 2.69E−06 45 K.repcat.e&g.2008.body.300.M

43 MER11A.ERVK.LTR.930.[920] 3.04E−06 46 K.repcat.e.2008.body.300.ERV

17 ERVL-C1.ERVL.LTR.334.[700] 3.04E−06 47 K.repcat.e.2008.body.300.LTR

288 LTR9.ERV1.LTR.1919.[459] 3.04E−06 48 K.repcat.e.2008.body.300.MLT

412 MLT1H.MaLR.LTR.9741.[277] 3.04E−06 49 K.repcat.e&g.2008.body.300.E

451 ERVL-E.ERVL.LTR.9525.[461] 3.86E−06 50 K.repcat.e&g.2008.body.300.M

157 MLT2B4.ERVL.LTR.4120.[305] 3.86E−06 51 K.repcat.e.2008.body.300.MLT

112 MLT1E1.MaLR.LTR.2001.[322] 3.86E−06 52 K.repcat.e.2008.body.300.THE

333 THE1C.MaLR.LTR.9731.[329] 3.86E−06 53 K.repcat.e.2008.body.300.Zap

121 Zaphod.Tip100.DNA.2063.[322] 3.86E−06 54K.repcat.e&g.2008.body.300.L

475 L1MC2.L1.LINE.5920.[505] 4.35E−06 55 K.repcat.e&g.2008.body.300.L

79198 LINE 4.35E−06 56 K.repcat.e&g.2008.body.300.M

53 MLT1F-int.MaLR.LTR.932.[387] 4.35E−06 57 K.repcat.e&g.2008.body.300.A

269 Arthur1.Tip100.DNA.4836.[241

4.90E−06 58 K.repcat.e&g.2008.body.300.H

20 HERVL-A2.ERVL.LTR.527.[1939] 4.90E−06 59 K.repcat.e&g.2008.body.300.H

49 HERVL40.ERVL.LTR.1217.[378] 5.51E−06 60 K.repcat.e&g.2008.body.300.L

888 L1MC1.L1.LINE.11868.[608] 5.51E−06 61 K.repcat.e&g.2008.body.300.L

14 L1PBb.L1.LINE.271.[1050] 5.51E−06 62 K.repcat.e&g.2008.body.300.L

109 LTR37A.ERV1.LTR.1957.[224] 5.51E−06 63 K.repcat.e.2008.body.300.MLT

796 MLT1J.MaLR.LTR.15375.[246] 5.51E−06 64 K.repcat.e&g.2008.body.300.L

729 L1MA9.L1.LINE.14394.[495] 6.18E−06 65 K.repcat.e.2008.body.300.LTR

90 LTR49.ERV1.LTR.1406.[325] 6.18E−06 66 K.repcat.e&g.2008.body.300.L

560 L1MA8.L1.LINE.9992.[497] 6.94E−06 67 K.repcat.e.2008.body.300.MST

349 MSTD.MaLR.LTR.7421.[291] 6.94E−06 68 K.repcat.e.2008.body.300.MER

173 MER57A.ERV1.LTR.2633.[290] 7.78E−06 69 K.repcat.e&g.2008.body.300.E

11 ERVL-D.ERVL.LTR.249.[796] 8.71E−06 70 K.repcat.e&g.2008.body.300.L

507 L1MD1.L1.LINE.6126.[612] 8.71E−06 71 K.repcat.e&g.2008.body.300.M

41 MLT1A0- 8.71E−06 72 K.repcat.e.2008.body.300.MER

86 MER41C.ERV1.LTR.799.[320] 8.71E−06 73 K.repcat.e.2008.body.300.MLT

213 MLT1H1.MaLR.LTR.3868.[316] 8.71E−06 74 K.repcat.e&g.2008.body.300.L

300 L1MB1.L1.LINE.5670.[521] 9.75E−06 75 K.repcat.e&g.2008.body.300.L

462 L1MCa.L1.LINE.7557.[512] 9.75E−06 76 K.repcat.e.2008.body.300.L1M

220 L1MA1.L1.LINE.3940.[1012] 9.75E−06 77 K.repcat.e.2008.body.300.LTR

109 LTR1B.ERV1.LTR.1147.[622] 9.75E−06 78 K.repcat.e&g.2008.body.300.L

710 L1MB4.L1.LINE.8956.[415] 1.09E−05 79 K.repcat.e.2008.body.300.THE

496 THE1D.MaLR.LTR.12381.[324] 1.09E−05 80 K.repcat.e&g.2008.body.300.L

5 LTR36-int.ERV1.LTR.71.[480] 1.22E−05 81 K.repcat.e&g.2008.body.300.H

100 HSMAR1.Mariner.DNA.703.[661] 1.36E−05 82K.repcat.e&g.2008.body.300.M

354 MLT1J2.MaLR.LTR.7867.[215] 1.36E−05 83 K.repcat.e.2008.body.300.MST

872 MSTA.MaLR.LTR.19102.[319] 1.36E−05 84 K.repcat.e&g.2008.body.300.L

944 L1MD2.L1.LINE.12388.[485] 1.51E−05 85 K.repcat.e&g.2008.body.300.L

513 L1PA13.L1.LINE.10722.[840] 1.51E−05 86 K.repcat.e&g.2008.body.300.L

26 LTR55.ERV.LTR.402.[366] 1.51E−05 87 K.repcat.e.2008.body.300.L1 53617L1 1.51E−05 88 K.repcat.e&g.2008.body.300.L

38 LOR1-int.ERV1.LTR.561.[435] 1.69E−05 89 K.repcat.e&g.2008.body.300.L

41 LTR22C.ERVK.LTR.378.[442] 1.69E−05 90 K.repcat.e&g.2008.body.300.M

136 MLT2A2.ERVL.LTR.3754.[411] 1.69E−05 91 K.repcat.e&g.2008.body.300.D

24141 DNA 1.88E−05 92 K.repcat.e&g.2008.body.300.T

902 Tigger1.MER2_type.DNA.11928.

1.88E−05 93 K.repcat.e&g.2008.body.300.L

307 L1MCc.L1.LINE.6889.[452] 2.09E−05 94 K.repcat.e.2008.body.300.LTR

314 LTR16A.ERVL.LTR.6873.[276] 2.09E−05 95 K.repcat.e&g.2008.body.300.M

11 MER72B.ERV1.LTR.177.[394] 2.32E−05 96 K.repcat.e&g.2008.body.300.L

275 L1MA10.L1.LINE.5419.[291] 2.57E−05 97 K.repcat.e&g.2008.body.300.M

114 MLT2F.ERVL.LTR.1917.[323] 2.57E−05 98 K.repcat.e&g.2008.body.300.T

14 THE1-int.MaLR.LTR.736.[300] 2.57E−05 99 K.repcat.e.2008.body.300.L1M

18 L1M2a.L1.LINE.515.[883] 2.57E−05 100 K.repcat.e.2008.body.300.MER

35 MER70A.ERVL.LTR.524.[386] 2.57E−05 101 K.repcat.e&g.2008.body.300.L

154 L1MCb.L1.LINE.2863.[624] 2.85E−05 102 K.repcat.e&g.2008.body.300.L

1127 L1ME3A.L1.LINE.16330.[362] 2.85E−05 103K.repcat.e&g.2008.body.300.L

7 LTR77.ERV1.LTR.149.[430] 2.85E−05 104 K.repcat.e&g.2008.body.300.t

10 tRNA-Ile- 2.85E−05 105 K.repcat.e&g.2008.body.300.M

10 MER66C- 3.16E−05 106 K.repcat.e&g.2008.body.300.t

1 tRNA-Ile- 3.16E−05 107 K.repcat.e.2008.body.300.ERV

17485 ERV1 3.16E−05 108 K.repcat.e.2008.body.300.MER

287 MER50.ERV1.LTR.2576.[431] 3.16E−05 109 K.repcat.e&g.2008.body.300.L

247 L1MA6.L1.LINE.4693.[601] 3.50E−05 110 K.repcat.e&g.2008.body.300.L

2011 L1ME1.L1.LINE.26938.[488] 3.50E−05 111 K.repcat.e&g.2008.body.300.L

288 L1PA17.L1.LINE.4722.[700] 3.50E−05 112 K.repcat.e.2008.body.300.LTR

97 LTR1D.ERV1.LTR.978.[707] 3.50E−05 113 K.repcat.e.2008.body.300.MER

18 MER61C.ERV1.LTR.284.[360] 3.50E−05 114 K.repcat.e&g.2008.body.300.L

573 L1MD3.L1.LINE.7482.[311] 3.87E−05 115 K.repcat.e&g.2008.body.300.L

723 L1PA4.L1.LINE.11462.[1602] 3.87E−05 116 K.repcat.e&g.2008.body.300.M

148 MLT2C1.ERVL.LTR.2455.[246] 3.87E−05 117 K.repcat.e.2008.body.300.MER

106 MER4D1.ERV1.LTR.1393.[464] 3.87E−05 118 K.repcat.e.2008.body.300.MER

111 MER9.ERVK.LTR.1128.[475] 3.87E−05 119 K.repcat.e&g.2008.body.300.L

454 L1M4b.L1.LINE.7423.[511] 4.28E−05 120 K.repcat.e.2008.body.300.L1M

509 L1MA4.L1.LINE.8983.[621] 4.28E−05 121 K.repcat.e.2008.body.300.LOR

65 LOR1b.ERV1.LTR.1086.[334] 4.28E−05 122 K.repcat.e.2008.body.300.PRI

26 PRIMA4_LTR.ERV1.LTR.344.[402

4.28E−05 123 K.repcat.e&g.2008.body.300.L

663 L1PA16.L1.LINE.13098.[813] 4.73E−05 124 K.repcat.e&g.2008.body.300.M

106 MER44B.MER2_type.DNA.1256.[3

4.73E−05 125 K.repcat.e&g.2008.body.300.M

16 MLT2B5.ERVL.LTR.461.[240] 4.73E−05 126 K.repcat.e.2008.body.300.MER

137 MER4B.ERV1.LTR.1709.[402] 4.73E−05 127 K.repcat.e&g.2008.body.300.H

14 HERVL66.ERVL.LTR.104.[735] 5.22E−05 128 K.repcat.e&g.2008.body.300.H

32 HUERS-P2.ERV1.LTR.242.[1082] 5.22E−05 129K.repcat.e.2008.body.300.HUE

66 HUERS-P3.ERV1.LTR.841.[806] 5.22E−05 130 K.repcat.e.2008.body.300.LTR

53 LTR29.ERV1.LTR.667.[307] 5.22E−05 131 K.repcat.e.2008.body.300.MER

68 MER57B.ERV1.LTR.1225.[343] 5.22E−05 132 K.repcat.e&g.2008.body.300.L

346 L1MA4A.L1.LINE.5823.[836] 5.76E−05 133 K.repcat.e&g.2008.body.300.L

342 L1PA10.L1.LINE.6962.[920] 5.76E−05 134 K.repcat.e&g.2008.body.300.M

34 MSTD-int.MaLR.LTR.730.[812] 5.76E−05 135 K.repcat.e&g.2008.body.300.L

105 L1P2.L1.LINE.2017.[1383] 6.35E−05 136 K.repcat.e&g.2008.body.300.L

5 LTR27B- 6.35E−05 137 K.repcat.e&g.2008.body.300.M

31 MER34B- 6.35E−05 138 K.repcat.e.2008.body.300.L1P

394 L1PA15.L1.LINE.8233.[962] 6.35E−05 139 K.repcat.e.2008.body.300.MER

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30 MER51B- 6.99E−05 141 K.repcat.e&g.2008.body.300.M

665 MER58A.MER1_type.DNA.12543.[

6.99E−05 142 K.repcat.e&g.2008.body.300.M

9 MER74C.ERVL.LTR.226.[323] 6.99E−05 143 K.repcat.e&g.2008.body.300.T

46 THE1B- 6.99E−05 144 K.repcat.e&g.2008.body.300.T

196 Tigger7.MER2_type.DNA.4405.[

6.99E−05 145 K.repcat.e.2008.body.300.MST

469 MSTB.MaLR.LTR.8397.[321] 6.99E−05 146 K.repcat.e&g.2008.body.300.C

133 Charlie10.MER1_type.DNA.2207

7.69E−05 147 K.repcat.e&g.2008.body.300.L

365 L1HS.L1.LINE.1696.[2016] 8.46E−05 148 K.repcat.e&g.2008.body.300.L

190 LTR16B.ERVL.LTR.3456.[292] 8.46E−05 149 K.repcat.e&g.2008.body.300.L

134 LTR41.ERVL.LTR.2357.[234] 8.46E−05 150 K.repcat.e&g.2008.body.300.L

286 LTR67.ERVL.LTR.6289.[175] 8.46E−05 151 K.repcat.e&g.2008.body.300.t

10 tRNA-His- 8.46E−05 152 K.repcat.e.2008.body.300.MER

219 MER63.AcHobo.DNA.3400.[139] 8.46E−05 153K.repcat.e&g.2008.body.300.H

44 HERVL-A1.ERVL.LTR.968.[2204] 9.30E−05 154K.repcat.e&g.2008.body.300.L

182 L1PB3.L1.LINE.3302.[827] 9.30E−05 155 K.repcat.e&g.2008.body.300.L

34 LTR51.ERV1.LTR.399.[424] 9.30E−05 156 K.repcat.e&g.2008.body.300.L

14 LTR75_1.ERV1.LTR.129.[320] 9.30E−05 157 K.repcat.e&g.2008.body.300.M

5338 MER2_type 9.30E−05 158 K.repcat.e&g.2008.body.300.M

3 MER66A- 9.30E−05 159 K.repcat.e&g.2008.body.300.M

118 MSR1.Satellite.Satellite.318

9.30E−05 160 K.repcat.e.2008.body.300.L1P

117 L1P.L1.LINE.1589.[520] 9.30E−05 161 K.repcat.e.2008.body.300.MER

243 MER41B.ERV1.LTR.2864.[370] 9.30E−05 162 K.repcat.e.2008.body.300.MLT

1331 MLT1D.MaLR.LTR.19943.[325] 9.30E−05 163K.repcat.e&g.2008.body.300.L

64 L1PA15- 1.02E−04 164 K.repcat.e&g.2008.body.300.L

507 L1PA7.L1.LINE.12334.[1556] 1.02E−04 165 K.repcat.e.2008.body.300.HER

36 HERVK11.ERVK.LTR.300.[1278] 1.02E−04 166 K.repcat.e.2008.body.300.LTR

274 LTR12.ERV1.LTR.964.[633] 1.02E−04 167 K.repcat.e.2008.body.300.MER

34 MER110.ERV1.LTR.736.[250] 1.02E−04 168 K.repcat.e&g.2008.body.300.L

183 L1P1.L1.LINE.2860.[838] 1.12E−04 169 K.repcat.e&g.2008.body.300.L

193 L1PA11.L1.LINE.3886.[997] 1.12E−04 170 K.repcat.e&g.2008.body.300.L

187 L1PA14.L1.LINE.3561.[941] 1.12E−04 171 K.repcat.e&g.2008.body.300.M

65 MER31- 1.12E−04 172 K.repcat.e.2008.body.300.LTR

331 LTR8.ERV1.LTR.3520.[439] 1.12E−04 173 K.repcat.e.2008.body.300.MER

163 MER4A1.ERV1.LTR.2150.[358] 1.12E−04 174 K.repcat.e&g.2008.body.300.L

182 L1MA5A.L1.LINE.3165.[541] 1.23E−04 175 K.repcat.e&g.2008.body.300.L

167 L1PB2.L1.LINE.2666.[831] 1.23E−04 176 K.repcat.e&g.2008.body.300.M

12 MLT1A-int.MaLR.LTR.428.[612] 1.23E−04 177K.repcat.e.2008.body.300.THE

156 THE1A.MaLR.LTR.4161.[319] 1.23E−04 178 K.repcat.e.2008.body.300.HER

34 HERVL.ERVL.LTR.1081.[547] 1.35E−04 179 K.repcat.e.2008.body.300.L1P

255 L1P4.L1.LINE.5156.[529] 1.35E−04 180 K.repcat.e&g.2008.body.300.L

547 L1PA5.L1.LINE.10904.[1449] 1.47E−04 181 K.repcat.e&g.2008.body.300.L

64 LTR16D.ERVL.LTR.1747.[217] 1.47E−04 182 K.repcat.e&g.2008.body.300.T

444 Tigger3b.MER2_type.DNA.4998.

1.47E−04 183 K.repcat.e.2008.body.300.MER

101 MER67C.ERV1.LTR.1468.[341] 1.47E−04 184 K.repcat.e&g.2008.body.300.L

174 LTR33A.ERVL.LTR.3521.[226] 1.61E−04 185 K.repcat.e.2008.body.300.LTR

516 LTR7.ERV1.LTR.2349.[407] 1.61E−04 186 K.repcat.e&g.2008.body.300.A

411 AluYg6.Alu.SINE.677.[254] 1.76E−04 187 K.repcat.e&g.2008.body.300.L

59 LTR47A.ERVL.LTR.873.[260] 1.76E−04 188 K.repcat.e&g.2008.body.300.M

151 MLT1H- 1.76E−04 189 K.repcat.e.2008.body.300.MER

37 MER67A.ERV1.LTR.484.[249] 1.76E−04 190 K.repcat.e&g.2008.body.300.L

73 L1MC4_3endX.L1.LINE.1031.[19

1.93E−04 191 K.repcat.e&g.2008.body.300.M

28 MER34-int.ERV1.LTR.394.[442] 1.93E−04 192K.repcat.e&g.2008.body.300.M

17 MLT1C-int.MaLR.LTR.421.[706] 1.93E−04 193K.repcat.e.2008.body.300.Alu

15 AluYd.Alu.SINE.65.[107] 1.93E−04 194 K.repcat.e.2008.body.300.L1M

452 L1M3.L1.LINE.7700.[374] 1.93E−04 195 K.repcat.e.2008.body.300.MER

32 MER4A1_.ERV1.LTR.380.[486] 1.93E−04 196 K.repcat.e.2008.body.300.MER

15 MER61D.ERV1.LTR.263.[361] 1.93E−04 197 K.repcat.e&g.2008.body.300.M

14 MER31B- 2.11E−04 198 K.repcat.e&g.2008.body.300.M

63 MER4B-int.ERV1.LTR.983.[492] 2.11E−04 199K.repcat.e&g.2008.body.300.M

199 MER94.AcHobo.DNA.4680.[105] 2.11E−04 200K.repcat.e&g.2008.body.300.t

2 tRNA-Pro- 2.11E−04 201 K.repcat.e.2008.body.300.Alu

76382 AluY.Alu.SINE.135761.[288] 2.11E−04 202K.repcat.e&g.2008.body.300.L

75 L1P5.L1.LINE.1531.[587] 2.30E−04 203 K.repcat.e&g.2008.body.300.L

1276 L1PA3.L1.LINE.10281.[1836] 2.30E−04 204K.repcat.e&g.2008.body.300.L

197 LTR16A1.ERVL.LTR.3898.[252] 2.30E−04 205K.repcat.e&g.2008.body.300.L

154 LTR8A.ERV1.LTR.2663.[482] 2.30E−04 206 K.repcat.e&g.2008.body.300.M

41 MER11B.ERVK.LTR.552.[932] 2.30E−04 207 K.repcat.e&g.2008.body.300.S

197952 SINE 2.30E−04 208 K.repcat.e&g.2008.body.300.t

7 tRNA-Asn- 2.30E−04 209 K.repcat.e&g.2008.body.300.A

13426 AluSc.Alu.SINE.48789.[278] 2.51E−04 210K.repcat.e&g.2008.body.300.L

1317 L1MEc.L1.LINE.21328.[480] 2.51E−04 211 K.repcat.e&g.2008.body.300.M

37 MER11D.ERVK.LTR.259.[745] 2.51E−04 212 K.repcat.e&g.2008.body.300.M

109 MER45B.Tip100.DNA.1173.[403] 2.51E−04 213K.repcat.e&g.2008.body.300.M

35 MER57B- 2.51E−04 214 K.repcat.e&g.2008.body.300.t

241 tRNA 2.51E−04 215 K.repcat.e.2008.body.300.MER

2231 MER5A.MER1_type.DNA.35576.[1

2.51E−04 216 K.repcat.e.2008.body.300.Tig

112 Tigger5.MER2_type.DNA.2895.[

2.51E−04 217 K.Sunami.PAPER 749 K. Sunami 2.51E−04 218 K.Yang.PAPER 810K. Yang 2.51E−04 219 K.repcat.e&g.2008.body.300.L

19 LTR22B.ERVK.LTR.219.[438] 2.73E−04 220 K.repcat.e&g.2008.body.300.L

44 LTR66.ERVL.LTR.515.[216] 2.73E−04 221 K.repcat.e.2008.body.300.L1M

243 L1MA5.L1.LINE.4086.[656] 2.73E−04 222 K.repcat.e.2008.body.300.L1P

205 L1P3.L1.LINE.4518.[756] 2.73E−04 223 K.repcat.e.2008.body.300.MLT

97 MLT1E3.MaLR.LTR.1701.[338] 2.73E−04 224 K.Chalitchagorn.PAPER 729 K.Chalitchagorn 2.73E−04 225 K.Woloszynska.PAPER 486 K. Woloszynska2.73E−04 226 K.Rago.PAPER 494 K. Rago 2.73E−04 227K.repcat.e&g.2008.body.300.L

13 LTR19A-int.ERV1.LTR.99.[996] 2.98E−04 228K.repcat.e&g.2008.body.300.M

917 MER5A1.MER1_type.DNA.14831.[

2.98E−04 229 K.repcat.e.2008.body.300.L1M

463 L1M2.L1.LINE.9352.[648] 2.98E−04 230 K.repcat.e.2008.body.300.MER

44 MER76.ERVL.LTR.674.[392] 2.98E−04 231 K.repcat.e&g.2008.body.300.M

138 MER11C.ERVK.LTR.825.[998] 3.24E−04 232 K.repcat.e&g.2008.body.300.M

29 MER41-int.ERV1.LTR.385.[552] 3.24E−04 233K.repcat.e.2008.body.300.L1P

349 L1PA8.L1.LINE.7715.[856] 3.24E−04 234 K.repcat.e.2008.body.300.MER

12 MER83B.ERV1.LTR.147.[252] 3.24E−04 235 K.repcat.e&g.2008.body.300.L

80 LTR12B.ERV1.LTR.450.[875] 3.52E−04 236 K.repcat.e&g.2008.body.300.L

25 LTR15.ERV1.LTR.311.[376] 3.52E−04 237 K.repcat.e.2008.body.300.MLT

1160 MLT1B.MaLR.LTR.17353.[278] 3.52E−04 238K.repcat.e.2008.body.300.MST

218 MSTB1.MaLR.LTR.4879.[326] 3.52E−04 239 K.repcat.e.2008.body.300.Tig

362 Tigger2.MER2_type.DNA.5206.[

3.52E−04 240 K.repcat.e&g.2008.body.300.L

651 L1MDa.L1.LINE.9760.[522] 3.83E−04 241 K.repcat.e&g.2008.body.300.M

7 MER65B-int.ERV1.LTR.53.[457] 3.83E−04 242 K.repcat.e.2008.body.300.L1M

741 L1MD.L1.LINE.10847.[339] 3.83E−04 243 K.repcat.e.2008.body.300.LTR

45 LTR36.ERV1.LTR.474.[382] 3.83E−04 244 K.repcat.e.2008.body.300.MER

14065 MER1_type 3.83E−04 245 K.repcat.e&g.2008.body.300.A

181521 Alu.Alu.SINE.6244.[52] 4.16E−04 246 K.repcat.e&g.2008.body.300.A

1300 AluSg1.Alu.SINE.6311.[280] 4.16E−04 247K.repcat.e&g.2008.body.300.L

35 L1M3b.L1.LINE.813.[836] 4.16E−04 248 K.repcat.e&g.2008.body.300.L

456 L1M4c.L1.LINE.7787.[595] 4.16E−04 249 K.repcat.e&g.2008.body.300.L

1764 L1ME3B.L1.LINE.27528.[351] 4.16E−04 250K.repcat.e&g.2008.body.300.L

24 LTR71A.ERV1.LTR.164.[385] 4.16E−04 251 K.repcat.e&g.2008.body.300.P

121 PiggyBac 4.16E−04 252 K.repcat.e.2008.body.300.L1M

31 L1M3d.L1.LINE.765.[649] 4.16E−04 253 K.repcat.e.2008.body.300.L1P

59 L1PB.L1.LINE.1520.[464] 4.16E−04 254 K.repcat.e.2008.body.300.MER

41 MER65D.ERV1.LTR.415.[277] 4.16E−04 255 K.repcat.e&g.2008.body.300.L

385 L1MA2.L1.LINE.6911.[992] 4.52E−04 256 K.repcat.e.2008.body.300.ERV

1507 ERVK 4.52E−04 257 K.repcat.e.2008.body.300.MER

85 MER34B.ERV1.LTR.1289.[331] 4.52E−04 258 K.repcat.e&g.2008.body.300.H

108 HSMAR2.Mariner.DNA.1721.[627

4.91E−04 259 K.repcat.e&g.2008.body.300.L

1204 L1MB8.L1.LINE.15156.[428] 4.91E−04 260 K.repcat.e&g.2008.body.300.L

136 L1PA12.L1.LINE.2320.[1117] 4.91E−04 261 K.repcat.e&g.2008.body.300.M

143 MER58C.MER1_type.DNA.2066.[1

4.91E−04 262 K.repcat.e&g.2008.body.300.H

1 HERVL-C1.ERVL.LTR.7.[980] 5.32E−04 263 K.repcat.e&g.2008.body.300.L

594 L1M1.L1.LINE.10118.[932] 5.32E−04 264 K.repcat.e&g.2008.body.300.L

8 L1M2a1.L1.LINE.142.[918] 5.32E−04 265 K.repcat.e&g.2008.body.300.L

596 L1MB2.L1.LINE.7699.[402] 5.32E−04 266 K.repcat.e&g.2008.body.300.L

135 LTR9B.ERV1.LTR.745.[398] 5.32E−04 267 K.repcat.e&g.2008.body.300.L

43 L1M3c.L1.LINE.1069.[583] 5.77E−04 268 K.repcat.e&g.2008.body.300.L

135 L1MDb.L1.LINE.1862.[510] 5.77E−04 269 K.repcat.e&g.2008.body.300.L

329 L1MEb.L1.LINE.5722.[435] 5.77E−04 270 K.repcat.e&g.2008.body.300.L

55 L1P4a.L1.LINE.731.[1306] 5.77E−04 271 K.repcat.e&g.2008.body.300.L

932 L1PA2.L1.LINE.4666.[2016] 5.77E−04 272 K.repcat.e&g.2008.body.300.M

19 MLT1A1- 5.77E−04 273 K.repcat.e&g.2008.body.300.M

34 MSTB-int.MaLR.LTR.617.[753] 5.77E−04 274 K.repcat.e.2008.body.300.MLT

140 MLT1J1.MaLR.LTR.3407.[217] 5.77E−04 275 K.repcat.e&g.2008.body.300.L

59 LTR14B.ERVK.LTR.358.[464] 6.25E−04 276 K.repcat.e.2008.body.300.L1M

1347 L1M4.L1.LINE.19504.[380] 6.25E−04 277 K.repcat.e.2008.body.300.L32561 L3.CR1.LINE.47228.[197] 6.25E−04 278 K.repcat.e.2008.body.300.LTR

54 LTR27B.ERV1.LTR.540.[461] 6.25E−04 279 K.repcat.e.2008.body.300.MER

296 MER30.MER1_type.DNA.3898.[19

6.25E−04 280 K.repcat.e.2008.body.300.MER

65 MER51B.ERV1.LTR.697.[303] 6.25E−04 281 K.repcat.e&g.2008.body.300.L

1122 L1ME2.L1.LINE.15797.[423] 6.76E−04 282 K.repcat.e&g.2008.body.300.L

115 L1MEa.L1.LINE.1665.[407] 6.76E−04 283 K.repcat.e&g.2008.body.300.M

292 MER103.DNA.DNA.6812.[111] 6.76E−04 284 K.repcat.e&g.2008.body.300.M

51 MSTA-int.MaLR.LTR.1927.[806] 6.76E−04 285K.repcat.e.2008.body.300.MER

98 MER4A.ERV1.LTR.1084.[386] 6.76E−04 286 K.repcat.e&g.2008.body.300.H

370 HAL1b.L1.LINE.7227.[255] 7.32E−04 287 K.repcat.e&g.2008.body.300.L

134 L1PA8A.L1.LINE.2210.[1386] 7.32E−04 288 K.repcat.e&g.2008.body.300.L

102 LTR7Y.ERV1.LTR.472.[361] 7.32E−04 289 K.repcat.e&g.2008.body.300.M

46 MER41A- 7.32E−04 290 K.repcat.e&g.2008.body.300.M

490 MER58B.MER1_type.DNA.6800.[2

7.32E−04 291 K.repcat.e.2008.body.300.Alu

6 AluYa.Alu.SINE.46.[110] 7.32E−04 292 K.repcat.e&g.2008.body.300.M

13 MLT1B-int.MaLR.LTR.463.[631] 7.91E−04 293K.repcat.e&g.2008.body.300.T

218 Tigger2a.MER2_type.DNA.3206.

7.91E−04 294 K.repcat.e.2008.body.300.HER

65 HERVIP10F.ERV1.LTR.318.[1464

7.91E−04 295 K.repcat.e.2008.body.300.LTR

113 LTR39.ERV1.LTR.1193.[393] 7.91E−04 296 K.repcat.e.2008.body.300.MER

29 MER54B.ERVL.LTR.417.[407] 7.91E−04 297 K.repcat.e&g.2008.body.300.L

542 L1MA3.L1.LINE.8131.[987] 8.55E−04 298 K.repcat.e&g.2008.body.300.L

68 LTR2B.ERV1.LTR.310.[453] 8.55E−04 299 K.repcat.e&g.2008.body.300.L

14 LTR57-int.ERVL.LTR.309.[560] 8.55E−04 300K.repcat.e&g.2008.body.300.L

17 LTR73.ERV1.LTR.205.[393] 8.55E−04 301 K.repcat.e&g.2008.body.300.L

4 LTR76-int.ERV1.LTR.8.[2020] 8.55E−04 302 K.repcat.e&g.2008.body.300.M

11 MER4C-int.ERV1.LTR.302.[703] 8.55E−04 303K.repcat.e&g.2008.body.300.M

15 MER57-int.ERV1.LTR.353.[460] 8.55E−04 304K.repcat.e&g.2008.body.300.M

1 MER67B-int.ERV1.LTR.8.[603] 8.55E−04 305 K.repcat.e.2008.body.300.MER

99 MER65A.ERV1.LTR.1296.[314] 8.55E−04 306 K.repcat.e&g.2008.body.300.M

57 MER44C.MER2_type.DNA.802.[49

9.24E−04 307 K.repcat.e&g.2008.body.300.M

13 MST-int.MaLR.LTR.563.[425] 9.24E−04 308 K.repcat.e.2008.body.300.L1P

123 L1PBa.L1.LINE.1915.[1205] 9.24E−04 309 K.repcat.e.2008.body.300.LTR

34 LTR46.ERV1.LTR.231.[325] 9.24E−04 310 K.repcat.e&g.2008.body.300.C

2938 CR1 9.97E−04 311 K.repcat.e&g.2008.body.300.H

83 HERVK22.ERVK.LTR.404.[1292] 9.97E−04 312 K.repcat.e&g.2008.body.300.L

34 L1M3e.L1.LINE.981.[813] 9.97E−04 313 K.repcat.e&g.2008.body.300.K

109 Kanga2_a.Tc2.DNA.1465.[277] 1.08E−03 314K.repcat.e&g.2008.body.300.L

903 L1MEd.L1.LINE.15988.[333] 1.08E−03 315 K.repcat.e&g.2008.body.300.M

301 MER20B.MER1_type.DNA.4150.[2

1.08E−03 316 K.repcat.e&g.2008.body.300.M

11 MER31A- 1.08E−03 317 K.repcat.e.2008.body.300.LTR

304 LTR2.ERV1.LTR.847.[415] 1.08E−03 318 K.repcat.e&g.2008.body.300.M

8 MER61C- 1.16E−03 319 K.repcat.e&g.2008.body.300.L

8 LTR56-int.ERV1.LTR.131.[551] 1.25E−03 320 K.repcat.e&g.2008.body.300.M

11 MER61-int.ERV1.LTR.150.[676] 1.25E−03 321K.repcat.e&g.2008.body.300.M

4 MER70A- 1.25E−03 322 K.repcat.e&g.2008.body.300.T

103 Tigger4(Zombi).MER2_type.DNA 1.25E−03 323K.repcat.e.2008.body.300.MER

18 MER34C.ERV1.LTR.257.[221] 1.25E−03 324 K.repcat.e&g.2008.body.300.A

2364 AluYb9.Alu.SINE.3147.[299] 1.35E−03 325K.repcat.e&g.2008.body.300.H

46 HERVK3.ERVK.LTR.341.[1001] 1.35E−03 326 K.repcat.e&g.2008.body.300.M

5 MER61F- 1.35E−03 327 K.repcat.e.2008.body.300.LTR

23 LTR38.ERV1.LTR.313.[381] 1.35E−03 328 K.repcat.e.2008.body.300.MER

14 MER92C.ERV1.LTR.334.[159] 1.35E−03 329 K.repcat.e&g.2008.body.300.L

750 L1MEe.L1.LINE.12492.[333] 1.45E−03 330 K.repcat.e&g.2008.body.300.L

99 LTR37B.ERV1.LTR.1958.[226] 1.45E−03 331 K.repcat.e&g.2008.body.300.L

18 LTR43B.ERV1.LTR.213.[318] 1.45E−03 332 K.repcat.e&g.2008.body.300.M

5 MER51-int.ERV1.LTR.150.[526] 1.45E−03 333 K.repcat.e.2008.body.300.LTR

19 LTR60.ERV1.LTR.250.[309] 1.45E−03 334 K.repcat.e.2008.body.300.L1M

972 L1M.L1.LINE.11466.[335] 1.56E−03 335 K.repcat.e.2008.body.300.L1M

1060 L1MC.L1.LINE.16426.[272] 1.56E−03 336 K.repcat.e.2008.body.300.MER

22 MER70B.ERVL.LTR.497.[302] 1.56E−03 337 K.repcat.e.2008.body.300.MLT

61 MLT1E1A.MaLR.LTR.1054.[326] 1.56E−03 338 K.repcat.e.2008.body.300.U121 U1.snRNA.snRNA.183.[129] 1.56E−03 339 K.repcat.e&g.2008.body.300.L

2100 L1MC4a.L1.LINE.28404.[336] 1.68E−03 340K.repcat.e&g.2008.body.300.L

24 LTR40c.ERVL.LTR.609.[321] 1.68E−03 341 K.repcat.e&g.2008.body.300.L

9 LTR68.ERV1.LTR.341.[293] 1.80E−03 342 K.repcat.e&g.2008.body.300.M

66 MER4A1- 1.80E−03 343 K.repcat.e&g.2008.body.300.M

97 MLT2A1.ERVL.LTR.3220.[327] 1.80E−03 344 K.repcat.e&g.2008.body.300.t

6 tRNA-Arg- 1.80E−03 345 K.repcat.e&g.2008.body.300.t

2 tRNA-Leu- 1.80E−03 346 K.repcat.e.2008.body.300.MER

39 MER110A.ERV1.LTR.644.[254] 1.80E−03 347 K.repcat.e.2008.body.300.MER

152 MER68.ERVL.LTR.1892.[361] 1.80E−03 348 K.repcat.e.2008.body.300.MER

40 MER75.PiggyBac.DNA.551.[334] 1.80E−03 349K.repcat.e&g.2008.body.300.L

4051 L1M5.L1.LINE.63689.[284] 1.94E−03 350 K.repcat.e&g.2008.body.300.L

1 LTR34-int.ERV1.LTR.26.[212] 1.94E−03 351 K.repcat.e&g.2008.body.300.M

93 MER119.MER1_type.DNA.1169.[2

1.94E−03 352 K.repcat.e&g.2008.body.300.M

21 MER21A- 1.94E−03 353 K.repcat.e&g.2008.body.300.M

12 MER21B- 1.94E−03 354 K.repcat.e&g.2008.body.300.M

146 MER77.ERVL.LTR.2380.[340] 1.94E−03 355 K.repcat.e&g.2008.body.300.M

86 MuDR 1.94E−03 356 K.repcat.e.2008.body.300.MER

95 MER39B.ERV1.LTR.1166.[382] 1.94E−03 357 K.repcat.e&g.2008.body.300.L

77 L1M3f.L1.LINE.1234.[941] 2.08E−03 358 K.repcat.e&g.2008.body.300.M

39 MER85.PiggyBac.DNA.892.[122] 2.08E−03 359K.repcat.e.2008.body.300.Cha

397 Charlie1.MER1_type.DNA.4911.

2.23E−03 360 K.repcat.e.2008.body.300.ERV

3 ERVL-C2.ERVL.LTR.54.[807] 2.23E−03 361 K.repcat.e.2008.body.300.MLT

258 MLT1F.MaLR.LTR.4498.[327] 2.23E−03 362 K.repcat.e&g.2008.body.300.C

80 Charlie9.MER1_type.DNA.1582.

2.39E−03 363 K.repcat.e&g.2008.body.300.E

22 ERVL-B1.ERVL.LTR.439.[1011] 2.39E−03 364 K.repcat.e&g.2008.body.300.M

1582 MER5B.MER1_type.DNA.24584.[1

2.39E−03 365 K.repcat.e&g.2008.body.300.M

322 MER7A.MER2_type.DNA.5173.[28

2.39E−03 366 K.repcat.e.2008.body.300.Alu

19770 AluSg.Alu.SINE.80825.[289] 2.39E−03 367K.repcat.e&g.2008.body.300.C

290 Charlie7.MER1_type.DNA.4721.

2.57E−03 368 K.repcat.e&g.2008.body.300.L

8 L1P4e.L1.LINE.221.[996] 2.57E−03 369 K.repcat.e&g.2008.body.300.L

137 LTR7B.ERV1.LTR.861.[364] 2.57E−03 370 K.repcat.e&g.2008.body.300.M

37 MER105.DNA.DNA.712.[145] 2.57E−03 371 K.repcat.e&g.2008.body.300.M

41 MER69B.Tip100.DNA.478.[511] 2.57E−03 372 K.repcat.e&g.2008.body.300.M

527 MLT1L.MaLR.LTR.11354.[209] 2.57E−03 373 K.repcat.e.2008.body.300.LTR

429 LTR1.ERV1.LTR.1396.[612] 2.57E−03 374 K.repcat.e&g.2008.body.300.M

181 MARNA.Mariner.DNA.3249.[181] 2.75E−03 375K.repcat.e&g.2008.body.300.M

85 MER6A.MER2_type.DNA.805.[428

2.75E−03 376 K.repcat.e&g.2008.body.300.M

255 MER82.MER2_type.DNA.3129.[35

2.75E−03 377 K.repcat.e.2008.body.300.L1M

2132 L1MC4.L1.LINE.29881.[332] 2.75E−03 378 K.repcat.e.2008.body.300.L1M

555 L1ME3.L1.LINE.7572.[348] 2.75E−03 379 K.repcat.e.2008.body.300.LTR

30 LTR24C.ERV1.LTR.380.[322] 2.75E−03 380 K.repcat.e.2008.body.300.LTR

27 LTR27.ERV1.LTR.403.[558] 2.75E−03 381 K.repcat.e&g.2008.body.300.A

116 AluJ/FRAM.Alu.SINE.1750.[74] 2.94E−03 382K.repcat.e&g.2008.body.300.L

24 L1M3de.L1.LINE.497.[598] 2.94E−03 383 K.repcat.e&g.2008.body.300.T

27 THE1D- 2.94E−03 384 K.repcat.e.2008.body.300.tRN

3 tRNA-Met_.tRNA.tRNA.39.[44] 2.94E−03 385 K.repcat.e&g.2008.body.300.H

77 HERVK9.ERVK.LTR.723.[1250] 3.15E−03 386 K.repcat.e&g.2008.body.300.L

1523 L1MC5.L1.LINE.20412.[260] 3.15E−03 387 K.repcat.e&g.2008.body.300.M

136 MER2B.MER2_type.DNA.2351.[15

3.15E−03 388 K.repcat.e&g.2008.body.300.M

2 MLT1E2- 3.15E−03 389 K.repcat.e&g.2008.body.300.T

1685 Tip100 3.15E−03 390 K.repcat.e.2008.body.300.MER

11 MER83C.ERV1.LTR.146.[299] 3.15E−03 391 K.repcat.e&g.2008.body.300.L

291 L1PA6.L1.LINE.5617.[1926] 3.37E−03 392 K.repcat.e&g.2008.body.300.L

653 L1PB1.L1.LINE.11421.[1064] 3.37E−03 393 K.repcat.e&g.2008.body.300.M

33 MER41B- 3.37E−03 394 K.repcat.e&g.2008.body.300.M

7 MLT1F1- 3.37E−03 395 K.repcat.e&g.2008.body.300.L

23 L1M2c.L1.LINE.585.[856] 3.61E−03 396 K.repcat.e&g.2008.body.300.M

63 MLT2C2.ERVL.LTR.1282.[249] 3.61E−03 397 K.repcat.e.2008.body.300.MST

62 MSTB2.MaLR.LTR.1595.[329] 3.61E−03 398 K.repcat.e&g.2008.body.300.B

104 BLACKJACK.AcHobo.DNA.2099.[3

3.85E−03 399 K.repcat.e&g.2008.body.300.H

42 HUERS-P1.ERV1.LTR.592.[986] 3.85E−03 400 K.repcat.e&g.2008.body.300.L

23 LOR1b-int.ERV1.LTR.354.[624] 3.85E−03 401K.repcat.e.2008.body.300.MER

125 MER49.ERV1.LTR.1296.[399] 3.85E−03 402 K.repcat.e.2008.body.300.MER

63 MER52D.ERV1.LTR.576.[932] 3.85E−03 403 K.repcat.e.2008.body.300.MER

17 MER61E.ERV1.LTR.308.[387] 3.85E−03 404 K.repcat.e&g.2008.body.300.M

1 MER41E-int.ERV1.LTR.14.[528] 4.12E−03 405 K.repcat.e&g.2008.body.300.M

117 MER44A.MER2_type.DNA.2119.[2

4.39E−03 406 K.repcat.e&g.2008.body.300.P

21 PABL_A- 4.39E−03 407 K.repcat.e.2008.body.300.HAL

1862 HAL1.L1.LINE.27468.[342] 4.39E−03 408 K.repcat.e&g.2008.body.300.A

3246 AluSg/x.Alu.SINE.25834.[162] 4.69E−03 409K.repcat.e&g.2008.body.300.M

39 MER101- 4.69E−03 410 K.repcat.e&g.2008.body.300.M

4 MER4D1-int.ERV1.LTR.53.[619] 4.69E−03 411 K.repcat.e.2008.body.300.LTR

42 LTR26.ERV1.LTR.604.[405] 4.69E−03 412 K.repcat.e&g.2008.body.300.L

17 L1P4d.L1.LINE.204.[1102] 5.00E−03 413 K.repcat.e.2008.body.300.Alu

3067 AluYa5.Alu.SINE.3978.[292] 5.00E−03 414K.repcat.e.2008.body.300.MER

714 MER3.MER1_type.DNA.10996.[14

5.00E−03 415 K.repcat.e.2008.body.300.tRN

1 tRNA-Met.tRNA.tRNA.48.[57] 5.00E−03 416 K.repcat.e&g.2008.body.300.L

7 L1P4c.L1.LINE.93.[937] 5.33E−03 417 K.repcat.e&g.2008.body.300.L

4 LTR24-int.ERV1.LTR.107.[555] 5.33E−03 418 K.repcat.e&g.2008.body.300.M

36 MER50-int.ERV1.LTR.488.[791] 5.33E−03 419K.repcat.e&g.2008.body.300.M

26 MER6B.MER2_type.DNA.656.[170

5.33E−03 420 K.repcat.e.2008.body.300.Alu

15732 AluSq.Alu.SINE.93297.[286] 5.33E−03 421K.repcat.e.2008.body.300.MER

350 MER21C.ERV1.LTR.4871.[411] 5.33E−03 422 K.repcat.e&g.2008.body.300.C

22 Charlie6.MER1_type.DNA.250.[

5.68E−03 423 K.repcat.e&g.2008.body.300.M

59 MER54A.ERVL.LTR.626.[458] 5.68E−03 424 K.repcat.e.2008.body.300.Alu

13437 AluSp.Alu.SINE.50469.[287] 5.68E−03 425K.repcat.e&g.2008.body.300.L

19 LTR72B.ERV1.LTR.176.[304] 6.05E−03 426 K.repcat.e&g.2008.body.300.M

299 MER1A.MER1_type.DNA.2968.[45

6.05E−03 427 K.repcat.e&g.2008.body.300.M

8 MER61D- 6.05E−03 428 K.repcat.e&g.2008.body.300.L

12 L1M2b.L1.LINE.318.[858] 6.44E−03 429 K.repcat.e&g.2008.body.300.L

93 LTR10F.ERV1.LTR.432.[415] 6.44E−03 430 K.repcat.e&g.2008.body.300.L

41 LTR53.ERVL.LTR.666.[362] 6.44E−03 431 K.repcat.e&g.2008.body.300.R

8 Ricksha_c.MuDR.DNA.121.[854] 6.44E−03 432 K.repcat.e&g.2008.body.300.L

462 LTR16C.ERVL.LTR.9063.[251] 6.86E−03 433 K.repcat.e&g.2008.body.300.L

143 LTR50.ERVL.LTR.2809.[267] 6.86E−03 434 K.repcat.e&g.2008.body.300.M

20 MSTC-int.MaLR.LTR.193.[799] 6.86E−03 435 K.repcat.e&g.2008.body.300.C

66 Cheshire.MER1_type.DNA.747.[

7.29E−03 436 K.repcat.e&g.2008.body.300.L

48 L1PBA1.L1.LINE.656.[1545] 7.29E−03 437 K.repcat.e&g.2008.body.300.M

178 MER46A.MER2_type.DNA.3411.[1

7.29E−03 438 K.repcat.e&g.2008.body.300.L

1775 L1MB7.L1.LINE.20238.[456] 7.75E−03 439 K.repcat.e&g.2008.body.300.M

2 MER67C-int.ERV1.LTR.24.[346] 7.75E−03 440 K.repcat.e&g.2008.body.300.t

3 tRNA-Thr- 7.75E−03 441 K.repcat.e.2008.body.300.HER

52 HERVK14.ERVK.LTR.297.[755] 7.75E−03 442 K.repcat.e&g.2008.body.300.M

15 MER21C- 8.24E−03 443 K.repcat.e&g.2008.body.300.M

139 MLT-int.MaLR.LTR.4461.[1279] 8.24E−03 444K.repcat.e&g.2008.body.300.T

428 Tc2 8.24E−03 445 K.repcat.e.2008.body.300.PAB

47 PABL_A.ERV1.LTR.514.[471] 8.24E−03 446 K.repcat.e&g.2008.body.300.M

632 MER1B.MER1_type.DNA.5233.[29

8.75E−03 447 K.repcat.e&g.2008.body.300.M

9 MER65C- 8.75E−03 448 K.repcat.e&g.2008.body.300.M

5 MER72-int.ERV1.LTR.69.[429] 8.75E−03 449 K.repcat.e&g.2008.body.300.T

54 Tigger6a.MER2_type.DNA.681.[

8.75E−03 450 K.repcat.e&g.2008.body.300.t

10 tRNA-Val- 8.75E−03 451 K.repcat.e.2008.body.300.LTR

16 LTR10G.ERV1.LTR.116.[432] 8.75E−03 452 K.repcat.e.2008.body.300.LTR

42 LTR30.ERV1.LTR.170.[560] 8.75E−03 453 K.repcat.e.2008.body.300.MER

51 MER72.ERV1.LTR.736.[435] 8.75E−03 454 K.repcat.e.2008.body.300.LTR

61 LTR40b.ERVL.LTR.1229.[270] 9.29E−03 455 K.repcat.e.2008.body.300.MER

118 MER8.MER2_type.DNA.1884.[188

9.29E−03 456 K.repcat.e&g.2008.body.300.M

6 MER4A1_- 9.86E−03 457 K.repcat.e&g.2008.body.300.t

7 tRNA-Val- 9.86E−03 458 K.repcat.e.2008.body.300.LOR

22 LOR1a.ERV1.LTR.789.[380] 9.86E−03 459 K.repcat.e&g.2008.body.300.L

37 LTR3A.ERVK.LTR.158.[396] 1.05E−02 460 K.repcat.e&g.2008.body.300.M

9 MER4E1-int.ERV1.LTR.75.[590] 1.05E−02 461 K.repcat.e&g.2008.body.300.U

127 U6.snRNA.snRNA.1666.[87] 1.05E−02 462 K.repcat.e.2008.body.300.LTR

486 LTR33.ERVL.LTR.9302.[253] 1.05E−02 463 K.repcat.e.2008.body.300.Ric

64 Ricksha.MuDR.DNA.1551.[287] 1.05E−02 464 K.repcat.e&g.2008.body.300.L

308 LTR12D.ERV1.LTR.502.[810] 1.11E−02 465 K.repcat.e&g.2008.body.300.L

13 LTR38C.ERV1.LTR.132.[373] 1.11E−02 466 K.repcat.e&g.2008.body.300.M

4 MER52A- 1.11E−02 467 K.repcat.e&g.2008.body.300.M

12 MER92A.ERV1.LTR.145.[271] 1.11E−02 468 K.repcat.e&g.2008.body.300.T

159 Tigger5a.MER2_type.DNA.2545.

1.11E−02 469 K.repcat.e.2008.body.300.MER

500 MER2.MER2_type.DNA.8174.[238

1.11E−02 470 K.repcat.e&g.2008.body.300.L

2335 L1ME4a.L1.LINE.38237.[216] 1.18E−02 471K.repcat.e&g.2008.body.300.S

126 SST1.centr.Satellite.565.[60

1.18E−02 472 K.repcat.e&g.2008.body.300.T

25 THE1A-int.MaLR.LTR.615.[948] 1.18E−02 473K.repcat.e&g.2008.body.300.M

17 MER41G.ERV1.LTR.105.[415] 1.24E−02 474 K.repcat.e&g.2008.body.300.M

4 MER75B.PiggyBac.DNA.111.[168

1.24E−02 475 K.repcat.e.2008.body.300.MER

35 MER41E.ERV1.LTR.355.[382] 1.24E−02 476 K.repcat.e&g.2008.body.300.E

20 ERVL-F.ERVL.LTR.459.[601] 1.32E−02 477 K.repcat.e&g.2008.body.300.H

38 HERVP71A.ERV1.LTR.190.[1344] 1.32E−02 478K.repcat.e&g.2008.body.300.L

19 LTR14A.ERVK.LTR.113.[329] 1.32E−02 479 K.repcat.e&g.2008.body.300.M

222 MER112.MER1_type.DNA.3729.[1

1.32E−02 480 K.repcat.e&g.2008.body.300.M

30 MER44D.MER2_type.DNA.334.[49

1.32E−02 481 K.repcat.e.2008.body.300.LTR

79 LTR54.ERV1.LTR.1087.[261] 1.32E−02 482 K.repcat.e&g.2008.body.300.A

45649 AluSx.Alu.SINE.332026.[290] 1.39E−02 483K.repcat.e&g.2008.body.300.H

35 HERV35I.ERV1.LTR.426.[594] 1.39E−02 484 K.repcat.e&g.2008.body.300.M

406 MER1_type? 1.39E−02 485 K.repcat.e&g.2008.body.300.M

38 MLT1D-int.MaLR.LTR.595.[731] 1.39E−02 486K.repcat.e.2008.body.300.LTR

19 LTR38B.ERV1.LTR.217.[386] 1.39E−02 487 K.repcat.e.2008.body.300.MER

265 MER21B.ERV1.LTR.3565.[442] 1.39E−02 488 K.repcat.e&g.2008.body.300.L

13 LTR25-int.ERV1.LTR.264.[950] 1.48E−02 489K.repcat.e&g.2008.body.300.M

134 MER46B.MER2_type.DNA.2000.[2

1.48E−02 490 K.repcat.e&g.2008.body.300.M

5 MLT1E-int.MaLR.LTR.109.[760] 1.48E−02 491 K.repcat.e.2008.body.300.MER

30 MER4D0.ERV1.LTR.463.[369] 1.48E−02 492 K.repcat.e.2008.body.300.tRN

2 tRNA-Leu- 1.48E−02 493 K.repcat.e&g.2008.body.300.A

562 AluYd8.Alu.SINE.853.[274] 1.56E−02 494 K.repcat.e&g.2008.body.300.M

30 MER65-int.ERV1.LTR.303.[493] 1.56E−02 495K.repcat.e.2008.body.300.MER

93 MER4C.ERV1.LTR.1172.[320] 1.56E−02 496 K.repcat.e&g.2008.body.300.L

14 L1P3b.L1.LINE.165.[1351] 1.65E−02 497 K.repcat.e&g.2008.body.300.L

9 LTR43-int.ERV1.LTR.97.[655] 1.65E−02 498 K.repcat.e&g.2008.body.300.M

9 MER76-int.ERVL.LTR.155.[543] 1.65E−02 499 K.repcat.e.2008.body.300.LTR

14 LTR76.ERV1.LTR.186.[480] 1.65E−02 500 K.repcat.e&g.2008.body.300.H

129 Harlequin.ERV1.LTR.610.[1500

1.74E−02 501 K.repcat.e&g.2008.body.300.H

13 HERV30.ERV1.LTR.61.[1647] 1.74E−02 502 K.repcat.e&g.2008.body.300.L

17 L1P4b.L1.LINE.275.[1316] 1.74E−02 503 K.repcat.e.2008.body.300.MER

58 MER65C.ERV1.LTR.683.[311] 1.74E−02 504 K.repcat.e.2008.body.300.MLT

1583 MLT1C.MaLR.LTR.19102.[313] 1.74E−02 505K.repcat.e&g.2008.body.300.M

15 MLT1-int.MaLR.LTR.283.[323] 1.84E−02 506 K.repcat.e&g.2008.body.300.t

2 tRNA-Thr- 1.84E−02 507 K.repcat.e&g.2008.body.300.L

30 LTR14C.ERVK.LTR.138.[512] 1.94E−02 508 K.repcat.e.2008.body.300.LTR

75 LTR56.ERV1.LTR.939.[275] 1.94E−02 509 K.repcat.e&g.2008.body.300.C

337 Charlie1a.MER1_type.DNA.3608

2.05E−02 510 K.repcat.e&g.2008.body.300.H

43 HY1.scRNA.scRNA.428.[97] 2.05E−02 511 K.repcat.e.2008.body.300.ERV

13 ERVL-B3.ERVL.LTR.194.[1101] 2.05E−02 512 K.repcat.e.2008.body.300.FAM

307 FAM.Alu.SINE.4424.[149] 2.05E−02 513 K.repcat.e&g.2008.body.300.A

40 ALR/Alpha.centr.Satellite.11

2.16E−02 514 K.repcat.e&g.2008.body.300.L

80 LTR49- 2.16E−02 515 K.repcat.e&g.2008.body.300.M

119 MADE2.Mariner.DNA.2609.[69] 2.16E−02 516K.repcat.e&g.2008.body.300.M

8 MLT1G-int.MaLR.LTR.121.[679] 2.16E−02 517 K.repcat.e&g.2008.body.300.T

21 THE1C- 2.16E−02 518 K.repcat.e.2008.body.300.Cha

246 Charlie2.MER1_type.DNA.3300.

2.16E−02 519 K.repcat.e&g.2008.body.300.A

56 AluYh9.Alu.SINE.183.[159] 2.28E−02 520 K.repcat.e&g.2008.body.300.L

5 LTR12C-int.ERV1.LTR.26.[561] 2.28E−02 521 K.repcat.e&g.2008.body.300.M

11 MER110- 2.28E−02 522 K.repcat.e.2008.body.300.MER

152 MER58.MER1_type.DNA.2330.[10

2.28E−02 523 K.repcat.e&g.2008.body.300.C

113 Charlie2a.MER1_type.DNA.1648

2.40E−02 524 K.repcat.e.2008.body.300.LTR

23 LTR19B.ERV1.LTR.277.[423] 2.40E−02 525 K.repcat.e.2008.body.300.MER

37 MER84.ERV1.LTR.345.[286] 2.40E−02 526 K.repcat.e&g.2008.body.300.L

22 LTR39-int.ERV1.LTR.295.[362] 2.53E−02 527K.repcat.e&g.2008.body.300.M

13 MER107.MER1_type.DNA.320.[15

2.53E−02 528 K.repcat.e&g.2008.body.300.M

186 MER46C.MER2_type.DNA.2705.[2

2.53E−02 529 K.repcat.e.2008.body.300.Kan

175 Kanga1.Tc2.DNA.3485.[171] 2.53E−02 530 K.repcat.e.2008.body.300.LTR

53 LTR48B.ERV1.LTR.1058.[346] 2.53E−02 531 K.repcat.e&g.2008.body.300.M

67 MER4-int.ERV1.LTR.918.[310] 2.66E−02 532 K.repcat.e&g.2008.body.300.M

9 MER93B-int 2.66E−02 533 K.repcat.e&g.2008.body.300.t

6 tRNA-Lys- 2.66E−02 534 K.repcat.e.2008.body.300.Alu

34 AluYb.Alu.SINE.151.[123] 2.66E−02 535 K.repcat.e.2008.body.300.LTR

342 LTR17.ERV1.LTR.830.[578] 2.66E−02 536 K.repcat.e.2008.body.300.LTR

12 LTR3B.ERVK.LTR.90.[391] 2.66E−02 537 K.repcat.e&g.2008.body.300.A

56 AluYc5.Alu.SINE.496.[51] 2.80E−02 538 K.repcat.e&g.2008.body.300.L

32 LTR1C.ERV1.LTR.242.[459] 2.80E−02 539 K.repcat.e&g.2008.body.300.M

7 MER95.ERV.LTR.154.[264] 2.80E−02 540 K.repcat.e&g.2008.body.300.M

11 MER9B.ERVK.LTR.61.[431] 2.80E−02 541 K.repcat.e&g.2008.body.300.t

6 tRNA-Ser- 2.80E−02 542 K.repcat.e&g.2008.body.300.R

4 Ricksha_0.MuDR.DNA.99.[617] 2.95E−02 543 K.repcat.e.2008.body.300.Alu

287 AluS.Alu.SINE.2733.[76] 2.95E−02 544 K.repcat.e&g.2008.body.300.B

48 BSR/Beta.Satellite.Satellite

3.10E−02 545 K.repcat.e&g.2008.body.300.M

56 MER63C.AcHobo.DNA.602.[467] 3.10E−02 546 K.repcat.e&g.2008.body.300.L

53 LTR64.ERV1.LTR.352.[292] 3.26E−02 547 K.repcat.e&g.2008.body.300.M

49 MER7C.MER2_type.DNA.588.[397

3.26E−02 548 K.repcat.e&g.2008.body.300.t

7 tRNA-Ser- 3.26E−02 549 K.repcat.e&g.2008.body.300.t

4 tRNA-Thr- 3.26E−02 550 K.repcat.e.2008.body.300.MER

203 MER52A.ERV1.LTR.1824.[1041] 3.26E−02 551K.repcat.e&g.2008.body.300.C

261 Charlie5.MER1_type.DNA.3466.

3.43E−02 552 K.repcat.e&g.2008.body.300.K

14 Kanga1c.Tc2.DNA.186.[374] 3.43E−02 553 K.repcat.e&g.2008.body.300.M

9 MER4E-int.ERV1.LTR.151.[712] 3.43E−02 554 K.repcat.e&g.2008.body.300.P

160 PRIMA4- 3.43E−02 555 K.repcat.e.2008.body.300.HER

778 HERVH.ERV1.LTR.5774.[958] 3.43E−02 556 K.repcat.e.2008.body.300.MER

51 MER4E.ERV1.LTR.694.[476] 3.43E−02 557 K.repcat.e.2008.body.300.MER

28 MER87.ERV1.LTR.405.[280] 3.43E−02 558 K.repcat.e&g.2008.body.300.L

134 LTR5_Hs.ERVK.LTR.601.[880] 3.60E−02 559 K.repcat.e&g.2008.body.300.M

1 MER34C_- 3.60E−02 560 K.repcat.e&g.2008.body.300.M

3 MLT1E1-int.MaLR.LTR.56.[576] 3.60E−02 561 K.repcat.e&g.2008.body.300.t

1 tRNA-Ala- 3.60E−02 562 K.repcat.e.2008.body.300.MLT

207 MLT1H2.MaLR.LTR.4227.[216] 3.60E−02 563 K.repcat.e.2008.body.300.PAB

26 PABL_B.ERV1.LTR.361.[373] 3.60E−02 564 K.repcat.e&g.2008.body.300.A

180 AluYc3.Alu.SINE.1758.[58] 3.78E−02 565 K.repcat.e&g.2008.body.300.H

13 HERVK14C.ERVK.LTR.81.[1701] 3.78E−02 566 K.repcat.e&g.2008.body.300.S

60 SATR2.Satellite.Satellite.25

3.78E−02 567 K.repcat.e.2008.body.300.tRN

4 tRNA-Arg- 3.78E−02 568 K.repcat.e&g.2008.body.300.7

58 7SK.RNA.RNA.715.[165] 3.97E−02 569 K.repcat.e&g.2008.body.300.H

148 HERV9.ERV1.LTR.1084.[1506] 3.97E−02 570 K.repcat.e&g.2008.body.300.M

102 MER5C.MER1_type.DNA.1512.[16

3.97E−02 571 K.repcat.e&g.2008.body.300.M

2 MLT1E1A- 3.97E−02 572 K.repcat.e&g.2008.body.300.T

71 Tigger5b.MER2_type.DNA.775.[

3.97E−02 573 K.repcat.e&g.2008.body.300.t

9 tRNA-Asp- 3.97E−02 574 K.repcat.e.2008.body.300.MER

40 MER91.Tip100.DNA.553.[55] 3.97E−02 575 K.repcat.e.2008.body.300.RNA

58 RNA 3.97E−02 576 K.repcat.e&g.2008.body.300.L

38 Looper.PiggyBac.DNA.514.[348

4.16E−02 577 K.repcat.e&g.2008.body.300.L

1 LTR10C-int.ERV1.LTR.11.[163] 4.16E−02 578 K.repcat.e.2008.body.300.LTR

46 LTR43.ERV1.LTR.436.[329] 4.16E−02 579 K.repcat.e.2008.body.300.MER

18 MER65B.ERV1.LTR.238.[194] 4.16E−02 580 K.repcat.e.2008.body.300.tRN

1 tRNA-Gln- 4.16E−02 581 K.repcat.e&g.2008.body.300.M

1 MER51E-int.ERV1.LTR.25.[430] 4.37E−02 582 K.repcat.e&g.2008.body.300.M

70 MER63D.AcHobo.DNA.1023.[205] 4.37E−02 583K.repcat.e&g.2008.body.300.M

80 MER74B.ERVL.LTR.936.[328] 4.37E−02 584 K.repcat.e.2008.body.300.MLT

1024 MLT1K.MaLR.LTR.18519.[227] 4.37E−02 585K.repcat.e&g.2008.body.300.M

5 MER83-int.ERV1.LTR.63.[852] 4.58E−02 586 K.repcat.e&g.2008.body.300.M

14 MER101B.ERV1.LTR.239.[304] 4.80E−02 587 K.repcat.e&g.2008.body.300.s

129 scRNA 4.80E−02 588 K.repcat.e.2008.body.300.Alu

219 AluJ.Alu.SINE.2554.[134] 4.80E−02 589 K.repcat.e&g.2008.body.300.H

7 HSAT4.centr.Satellite.96.[24

5.03E−02 590 K.repcat.e&g.2008.body.300.O

101 ORSL.Tip100.DNA.1181.[165] 5.03E−02 591 K.repcat.e.2008.body.300.LTR

68 LTR48.ERV1.LTR.1227.[342] 5.03E−02 592 K.repcat.e&g.2008.body.300.A

795 AluSq/x.Alu.SINE.7043.[122] 5.26E−02 593K.repcat.e&g.2008.body.300.H

3 HSATI.Satellite.Satellite.43

5.26E−02 594 K.repcat.e&g.2008.body.300.L

1556 L1MB3.L1.LINE.15139.[387] 5.26E−02 595 K.repcat.e&g.2008.body.300.M

45 MER65A- 5.26E−02 596 K.repcat.e.2008.body.300.LTR

16 LTR57.ERVL.LTR.234.[327] 5.26E−02 597 K.repcat.e&g.2008.body.300.A

33 AluYa5/8.Alu.SINE.112.[108] 5.51E−02 598 K.repcat.e&g.2008.body.300.H

13 HERVKC4.ERVK.LTR.63.[885] 5.51E−02 599 K.repcat.e&g.2008.body.300.L

30 LTR18A.ERVL.LTR.250.[313] 5.51E−02 600 K.repcat.e&g.2008.body.300.M

7 MER39B-int.ERV1.LTR.62.[638] 5.51E−02 601 K.repcat.e&g.2008.body.300.M

1 Merlin 5.51E−02 602 K.repcat.e&g.2008.body.300.M

1 Merlin1_HS.Merlin.DNA.53.[33

5.51E−02 603 K.repcat.e&g.2008.body.300.L

3 LTR48B- 5.76E−02 604 K.repcat.e&g.2008.body.300.M

3 MER6C.MER2_type.DNA.136.[148

5.76E−02 605 K.repcat.e.2008.body.300.FRA

1620 FRAM.Alu.SINE.21803.[149] 5.76E−02 606 K.repcat.e.2008.body.300.MER

131 MER66B.ERV1.LTR.1407.[302] 5.76E−02 607 K.repcat.e&g.2008.body.300.M

3 MER87-int.ERV1.LTR.25.[449] 6.03E−02 608 K.repcat.e&g.2008.body.300.t

7 tRNA-Gly- 6.03E−02 609 K.repcat.e.2008.body.300.MLT

152 MLT1G.MaLR.LTR.3459.[318] 6.03E−02 610 K.repcat.e.2008.body.300.tRN

4 tRNA-Glu- 6.03E−02 611 K.repcat.e&g.2008.body.300.M

26 MER68-int.ERVL.LTR.344.[465] 6.30E−02 612K.repcat.e&g.2008.body.300.A

52 AluYa8.Alu.SINE.107.[226] 6.59E−02 613 K.repcat.e&g.2008.body.300.M

7 MER84-int.ERV1.LTR.174.[637] 6.59E−02 614 K.repcat.e&g.2008.body.300.M

15 MLT1G1- 6.59E−02 615 K.repcat.e.2008.body.300.HER

30 HERVI.ERV1.LTR.124.[2141] 6.59E−02 616 K.repcat.e&g.2008.body.300.H

107 HERV17.ERV1.LTR.919.[982] 6.88E−02 617 K.repcat.e&g.2008.body.300.M

1 MER52C-int.ERV1.LTR.67.[636] 6.88E−02 618 K.repcat.e&g.2008.body.300.U

13 U3.snRNA.snRNA.228.[102] 6.88E−02 619 K.repcat.e.2008.body.300.LTR

10 LTR59.ERV1.LTR.121.[337] 6.88E−02 620 K.repcat.e.2008.body.300.MER

38 MER61B.ERV1.LTR.409.[332] 7.19E−02 621 K.repcat.e.2008.body.300.MER

41 MER66A.ERV1.LTR.346.[353] 7.19E−02 622 K.repcat.e&g.2008.body.300.L

8 LTR48-int.ERV1.LTR.107.[433] 7.50E−02 623 K.repcat.e.2008.body.300.LTR

33 LTR45B.ERV1.LTR.417.[324] 7.50E−02 624 K.repcat.e&g.2008.body.300.a

12 acro 7.83E−02 625 K.repcat.e&g.2008.body.300.A

12 ACRO1.acro.Satellite.40.[730

7.83E−02 626 K.repcat.e&g.2008.body.300.H

25 HERVL74.ERVL.LTR.473.[425] 7.83E−02 627 K.repcat.e&g.2008.body.300.L

56 LTR32.ERVL.LTR.1289.[281] 7.83E−02 628 K.repcat.e&g.2008.body.300.L

16 LTR23-int.ERV1.LTR.219.[363] 8.17E−02 629K.repcat.e&g.2008.body.300.L

3 LTR27-int.ERV1.LTR.76.[1024] 8.17E−02 630 K.repcat.e&g.2008.body.300.M

25 MER89-int.ERV1.LTR.614.[493] 8.17E−02 631K.repcat.e&g.2008.body.300.L

2 LTR1D-int.ERV1.LTR.40.[2150] 8.52E−02 632 K.repcat.e&g.2008.body.300.L

34 LTR45C.ERV1.LTR.393.[324] 8.52E−02 633 K.repcat.e&g.2008.body.300.U

4 U17.snRNA.snRNA.9.[174] 8.52E−02 634 K.repcat.e.2008.body.300.Alu

10719 AluJo.Alu.SINE.138391.[257] 8.52E−02 635K.repcat.e&g.2008.body.300.L

4 LTR9-int.ERV1.LTR.51.[921] 8.88E−02 636 K.repcat.e.2008.body.300.LTR

13 LTR22.ERVK.LTR.103.[478] 8.88E−02 637 K.repcat.e&g.2008.body.300.L

29 LTR10A.ERV1.LTR.301.[449] 9.26E−02 638 K.repcat.e&g.2008.body.300.L

4 LTR8-int.ERV1.LTR.53.[752] 9.26E−02 639 K.repcat.e&g.2008.body.300.M

196 MER81.AcHobo.DNA.3623.[94] 9.26E−02 640 K.repcat.e&g.2008.body.300.M

10 MER83B- 9.26E−02 641 K.repcat.e&g.2008.body.300.P

8 PRIMA4_LTR- 9.26E−02 642 K.repcat.e&g.2008.body.300.t

3 tRNA-Arg- 9.26E−02 643 K.repcat.e.2008.body.300.tRN

1 tRNA-Ser- 9.26E−02 644 K.repcat.e&g.2008.body.300.L

21 L1M3a.L1.LINE.683.[590] 9.64E−02 645 K.repcat.e&g.2008.body.300.M

22 MER102a.MER1_type.DNA.309.[2

9.64E−02 646 K.repcat.e&g.2008.body.300.M

581 MER33.MER1_type.DNA.8040.[21

9.64E−02 647 K.repcat.e.2008.body.300.MER

17 MER61F.ERV1.LTR.148.[438] 9.64E−02 648 K.repcat.e&g.2008.body.300.L

1 LTR2-int.ERV1.LTR.5.[222] 1.00E−01 649 K.repcat.e&g.2008.body.300.M

91 MER97c.MER1_type?.DNA.1428.[

1.00E−01 650 K.repcat.e&g.2008.body.300.L

26 LTR3B_.ERVK.LTR.245.[336] 1.05E−01 651 K.repcat.e&g.2008.body.300.t

6 tRNA-Leu- 1.05E−01 652 K.repcat.e&g.2008.body.300.A

10131 AluJb.Alu.SINE.125688.[259] 1.09E−01 653K.repcat.e&g.2008.body.300.L

43 LTR26E.ERV1.LTR.307.[375] 1.09E−01 654 K.repcat.e&g.2008.body.300.R

96 REP522.telo.Satellite.217.[6

1.09E−01 655 K.repcat.e.2008.body.300.LTR

29 LTR28.ERV1.LTR.513.[593] 1.09E−01 656 K.repcat.e&g.2008.body.300.M

22 MER73.ERVL.LTR.270.[408] 1.13E−01 657 K.repcat.e&g.2008.body.300.t

134 telo 1.13E−01 658 K.repcat.e&g.2008.body.300.M

48 MER61A- 1.18E−01 659 K.repcat.e&g.2008.body.300.c

315 centr 1.22E−01 660 K.repcat.e&g.2008.body.300.C

163 Charlie1b.MER1_type.DNA.1902

1.22E−01 661 K.repcat.e&g.2008.body.300.M

8 MER39-int.ERV1.LTR.185.[359] 1.22E−01 662 K.repcat.e&g.2008.body.300.M

12 MER61B- 1.22E−01 663 K.repcat.e&g.2008.body.300.S

921 Satellite 1.27E−01 664 K.repcat.e&g.2008.body.300.L

4 LTR19-int.ERV1.LTR.46.[890] 1.32E−01 665 K.repcat.e&g.2008.body.300.M

12 MER99.DNA.DNA.277.[347] 1.32E−01 666 K.repcat.e&g.2008.body.300.t

1 tRNA-Asn- 1.32E−01 667 K.repcat.e.2008.body.300.MER

58 MER41D.ERV1.LTR.435.[299] 1.32E−01 668 K.repcat.e&g.2008.body.300.M

6 MER41C- 1.37E−01 669 K.repcat.e&g.2008.body.300.t

7 tRNA-Gly- 1.37E−01 670 K.repcat.e.2008.body.300.FLA

129 FLAM.Alu.SINE.1401.[62] 1.37E−01 671 K.repcat.e.2008.body.300.GSA

50 GSAT.centr.Satellite.65.[367

1.37E−01 672 K.repcat.e.2008.body.300.LTR

16 LTR10E.ERV1.LTR.253.[458] 1.37E−01 673 K.repcat.e&g.2008.body.300.L

1 LTR10B-int.ERV1.LTR.6.[901] 1.42E−01 674 K.repcat.e&g.2008.body.300.M

18 MER97b.MER1_type?.DNA.194.[3

1.42E−01 675 K.repcat.e.2008.body.300.LTR

3363 LTR12_.ERV1.LTR.664.[497] 1.42E−01 676 K.repcat.e.2008.body.300.MER

141 MER21A.ERV1.LTR.1793.[398] 1.42E−01 677 K.repcat.e&g.2008.body.300.M

3 MER83C-int.ERV1.LTR.39.[927] 1.48E−01 678 K.repcat.e&g.2008.body.300.t

13 tRNA-Glu- 1.48E−01 679 K.repcat.e.2008.body.300.LTR

22 LTR19C.ERV1.LTR.213.[410] 1.48E−01 680 K.repcat.e&g.2008.body.300.A

313 AluJ/FLAM.Alu.SINE.3444.[78] 1.53E−01 681K.repcat.e&g.2008.body.300.C

212 Charlie4a.MER1_type.DNA.2329

1.53E−01 682 K.repcat.e&g.2008.body.300.M

141 MER115.Tip100.DNA.2382.[290] 1.53E−01 683K.repcat.e&g.2008.body.300.M

4408 MIR3.MIR.SINE.70044.[121] 1.53E−01 684 K.repcat.e&g.2008.body.300.t

4 tRNA-Ala- 1.53E−01 685 K.repcat.e.2008.body.300.LTR

37 LTR24B.ERV1.LTR.457.[293] 1.53E−01 686 K.repcat.e&g.2008.body.300.H

51 HY3.scRNA.scRNA.509.[87] 1.59E−01 687 K.repcat.e&g.2008.body.300.K

27 Kanga1a.Tc2.DNA.310.[392] 1.59E−01 688 K.repcat.e&g.2008.body.300.M

16 MER7D.MER2_type.DNA.397.[163

1.59E−01 689 K.repcat.e&g.2008.body.300.L

1 LTR10A- 1.65E−01 690 K.repcat.e.2008.body.300.MER

60 MER45.Tip100.DNA.678.[86] 1.65E−01 691 K.repcat.e&g.2008.body.300.H

87 HERVIP10FH.ERV1.LTR.594.[104

1.77E−01 692 K.repcat.e&g.2008.body.300.L

34 LTR5A.ERVK.LTR.250.[947] 1.77E−01 693 K.repcat.e&g.2008.body.300.t

2 tRNA-Leu- 1.77E−01 694 K.repcat.e.2008.body.300.MER

70 MER34C_.ERV1.LTR.1038.[282] 1.77E−01 695 K.repcat.e.2008.body.300.MER

80 MER93B.ERV1.LTR.989.[269] 1.77E−01 696 K.repcat.e&g.2008.body.300.A

283 AluSp/q.Alu.SINE.2568.[100] 1.83E−01 697K.repcat.e&g.2008.body.300.A

15 AluYb8.Alu.SINE.68.[161] 1.83E−01 698 K.repcat.e&g.2008.body.300.C

5 Charlie11.MER1_type.DNA.87.[

1.83E−01 699 K.repcat.e&g.2008.body.300.P

13 PRIMA41- 1.83E−01 700 K.repcat.e.2008.body.300.LTR

51 LTR52.ERVL.LTR.1035.[277] 1.83E−01 701 K.repcat.e.2008.body.300.MER

94 MER4E1.ERV1.LTR.1057.[396] 1.83E−01 702 K.repcat.e&g.2008.body.300.M

51 MLT1G3.MaLR.LTR.596.[291] 1.90E−01 703 K.repcat.e&g.2008.body.300.L

1 LTR29-int.ERV1.LTR.55.[532] 1.96E−01 704 K.repcat.e&g.2008.body.300.M

2 MER110A- 1.96E−01 705 K.repcat.e&g.2008.body.300.M

215 MER96B.MER1_type?.DNA.2121.[

1.96E−01 706 K.repcat.e.2008.body.300.LTR

12 LTR3.ERVK.LTR.83.[383] 1.96E−01 707 K.repcat.e&g.2008.body.300.U

53 U2.snRNA.snRNA.1053.[44] 2.03E−01 708 K.repcat.e&g.2008.body.300.L

91 LTR2C.ERV1.LTR.237.[343] 2.10E−01 709 K.repcat.e&g.2008.body.300.U

1 U8.snRNA.snRNA.30.[110] 2.10E−01 710 K.repcat.e&g.2008.body.300.M

62 MER45C.Tip100.DNA.1080.[297] 2.17E−01 711K.repcat.e&g.2008.body.300.t

7 tRNA-Phe- 2.17E−01 712 K.repcat.e&g.2008.body.300.L

38 LTR62.ERVL.LTR.312.[425] 2.24E−01 713 K.repcat.e&g.2008.body.300.P

10 PRIMAX- 2.24E−01 714 K.repcat.e&g.2008.body.300.H

3 HERVK11D.ERVK.LTR.57.[1690] 2.32E−01 715 K.repcat.e&g.2008.body.300.M

9 MER66B- 2.32E−01 716 K.repcat.e&g.2008.body.300.M

7 MER70-int.ERVL.LTR.124.[401] 2.32E−01 717 K.repcat.e.2008.body.300.LTR

71 LTR23.ERV1.LTR.840.[205] 2.32E−01 718 K.repcat.e&g.2008.body.300.C

29 Charlie2b.MER1_type.DNA.502.

2.39E−01 719 K.repcat.e.2008.body.300.tRN

6 tRNA-Ala- 2.39E−01 720 K.repcat.e&g.2008.body.300.M

192 MER117.MER1_type.DNA.4409.[1

2.47E−01 721 K.repcat.e&g.2008.body.300.M

16 MER97a.MER1_type?.DNA.237.[3

2.47E−01 722 K.repcat.e.2008.body.300.tRN

2 tRNA-Ser- 2.47E−01 723 K.repcat.e&g.2008.body.300.L

5 LTR38-int.ERV1.LTR.126.[481] 2.55E−01 724 K.repcat.e&g.2008.body.300.L

3 LTR69.ERVL.LTR.140.[376] 2.55E−01 725 K.repcat.e&g.2008.body.300.M

101 MER104.Tc2.DNA.2013.[149] 2.55E−01 726 K.repcat.e&g.2008.body.300.t

3 tRNA-Pro- 2.55E−01 727 K.repcat.e&g.2008.body.300.B

24 BC200.scRNA.scRNA.253.[134] 2.63E−01 728 K.repcat.e&g.2008.body.300.C

4 CER.Satellite.Satellite.35.[

2.63E−01 729 K.repcat.e&g.2008.body.300.C

17 Charlie12.MER1_type.DNA.164.

2.63E−01 730 K.repcat.e&g.2008.body.300.T

50 Tigger8.MER2_type.DNA.837.[2

2.63E−01 731 K.repcat.e&g.2008.body.300.L

27 LTR42.ERVL.LTR.287.[361] 2.72E−01 732 K.repcat.e&g.2008.body.300.L

12 LTR10B1- 2.80E−01 733 K.repcat.e&g.2008.body.300.L

111 LTR5B.ERVK.LTR.420.[781] 2.80E−01 734 K.repcat.e&g.2008.body.300.M

70 MER69A.Tip100.DNA.1046.[140] 2.89E−01 735K.repcat.e.2008.body.300.HER

116 HERVK.SVA, ERVK.Other, LTR.361

2.89E−01 736 K.repcat.e&g.2008.body.300.7

99 7SLRNA.srpRNA.srpRNA.937.[24

2.98E−01 737 K.repcat.e&g.2008.body.300.F

2632 FLAM_C.Alu.SINE.34861.[125] 2.98E−01 738K.repcat.e&g.2008.body.300.L

39 LTR26B.ERV1.LTR.436.[324] 2.98E−01 739 K.repcat.e&g.2008.body.300.s

99 srpRNA 2.98E−01 740 K.repcat.e&g.2008.body.300.t

1 tRNA-Ser- 2.98E−01 741 K.repcat.e.2008.body.300.MER

95 MER51A.ERV1.LTR.953.[414] 2.98E−01 742 K.repcat.e.2008.body.300.MER

67 MER96.MER1_type?.DNA.1232.[1

2.98E−01 743 K.repcat.e&g.2008.body.300.F

1265 FLAM_A.Alu.SINE.17781.[117] 3.07E−01 744K.repcat.e&g.2008.body.300.M

33 MER21-int.ERV1.LTR.385.[455] 3.07E−01 745K.repcat.e&g.2008.body.300.M

44 MER91C.Tip100.DNA.1249.[92] 3.07E−01 746 K.repcat.e.2008.body.300.LTR

2691 LTR12C.ERV1.LTR.2616.[1340] 3.07E−01 747K.repcat.e&g.2008.body.300.L

85 LTR12E.ERV1.LTR.127.[781] 3.16E−01 748 K.repcat.e&g.2008.body.300.M

70 MLT2E.ERVL.LTR.1362.[250] 3.16E−01 749 K.repcat.e.2008.body.300.LTR

30 LTR75.ERVL.LTR.404.[321] 3.16E−01 750 K.repcat.e.2008.body.300.MER

97 MER31B.ERV1.LTR.1459.[309] 3.16E−01 751 K.repcat.e&g.2008.body.300.E

4 ERVL-B2.ERVL.LTR.153.[1038] 3.25E−01 752 K.repcat.e&g.2008.body.300.M

363 MER113.MER1_type.DNA.4474.[1

3.25E−01 753 K.repcat.e&g.2008.body.300.t

3 tRNA-Pro- 3.25E−01 754 K.repcat.e.2008.body.300.LTR

10 LTR45.ERV1.LTR.179.[297] 3.25E−01 755 K.repcat.e&g.2008.body.300.L

5 LTR58.ERV1.LTR.83.[344] 3.35E−01 756 K.repcat.e&g.2008.body.300.M

72 MER92B.ERV1.LTR.870.[297] 3.35E−01 757 K.repcat.e&g.2008.body.300.U

26 U13_.snRNA.snRNA.304.[98] 3.35E−01 758 K.repcat.e&g.2008.body.300.U

7 U5.snRNA.snRNA.205.[55] 3.35E−01 759 K.repcat.e&g.2008.body.300.t

3 tRNA-Arg- 3.44E−01 760 K.repcat.e.2008.body.300.Tig

19 Tigger6.MER2_type.DNA.253.[2

3.44E−01 761 K.repcat.e&g.2008.body.300.L

10 LTR21B.ERV1.LTR.58.[342] 3.64E−01 762 K.repcat.e&g.2008.body.300.M

6 MLT1F2- 3.64E−01 763 K.repcat.e&g.2008.body.300.A

118 AluJo/FRAM.Alu.SINE.1339.[14

3.75E−01 764 K.repcat.e&g.2008.body.300.L

2 LTR10E-int.ERV1.LTR.8.[311] 3.75E−01 765 K.repcat.e&g.2008.body.300.Z

45 Zaphod2.Tip100.DNA.715.[196] 3.75E−01 766K.repcat.e.2008.body.300.Cha

91 Charlie4.MER1_type.DNA.1363.

3.75E−01 767 K.repcat.e.2008.body.300.MER

39 MER83.ERV1.LTR.435.[329] 3.75E−01 768 K.repcat.e.2008.body.300.LTR

26 LTR19A.ERV1.LTR.417.[359] 3.85E−01 769 K.repcat.e&g.2008.body.300.A

21 AluJ/monomer.Alu.SINE.329.[5

3.96E−01 770 K.repcat.e&g.2008.body.300.L

35 LTR18B.ERVL.LTR.382.[423] 3.96E−01 771 K.repcat.e&g.2008.body.300.L

23 LTR52-int.ERVL.LTR.338.[508] 3.96E−01 772K.repcat.e&g.2008.body.300.M

3 MER52-int.ERV1.LTR.136.[864] 3.96E−01 773 K.repcat.e&g.2008.body.300.M

332 MER53.DNA.DNA.5686.[128] 3.96E−01 774 K.repcat.e&g.2008.body.300.L

822 L1MB5.L1.LINE.8813.[405] 4.06E−01 775 K.repcat.e&g.2008.body.300.L

7 LTR24B- 4.06E−01 776 K.repcat.e&g.2008.body.300.L

23 LTR44.ERV1.LTR.201.[309] 4.06E−01 777 K.repcat.e&g.2008.body.300.H

42 HERVL18.ERVL.LTR.531.[760] 4.17E−01 778 K.repcat.e&g.2008.body.300.L

34 LTR35.ERV1.LTR.306.[301] 4.17E−01 779 K.repcat.e&g.2008.body.300.L

34 LTR65.ERV1.LTR.452.[268] 4.17E−01 780 K.repcat.e&g.2008.body.300.M

7 MSTB1-int.MaLR.LTR.179.[670] 4.17E−01 781 K.repcat.e&g.2008.body.300.t

4 tRNA-Tyr- 4.17E−01 782 K.repcat.e.2008.body.300.MER

79 MER89.ERV1.LTR.1339.[310] 4.17E−01 783 K.repcat.e&g.2008.body.300.L

4 LTR19B-int.ERV1.LTR.43.[730] 4.28E−01 784 K.repcat.e&g.2008.body.300.M

271 MER102b.MER1_type.DNA.3930.[

4.28E−01 785 K.repcat.e.2008.body.300.LTR

50 LTR10C.ERV1.LTR.507.[462] 4.28E−01 786 K.repcat.e&g.2008.body.300.L

383 L3b.CR1.LINE.7618.[138] 4.40E−01 787 K.repcat.e&g.2008.body.300.L

98 LTR13A.ERVK.LTR.182.[795] 4.40E−01 788 K.repcat.e&g.2008.body.300.L

123 LTR13_.ERVK.LTR.36.[891] 4.40E−01 789 K.repcat.e&g.2008.body.300.L

5 LTR19C- 4.40E−01 790 K.repcat.e&g.2008.body.300.M

2084 MIRm.MIR.SINE.32156.[90] 4.51E−01 791 K.repcat.e&g.2008.body.300.P

11 PABL_B- 4.51E−01 792 K.repcat.e.2008.body.300.For

26 FordPrefect.Tip100.DNA.410.[

4.51E−01 793 K.repcat.e.2008.body.300.LTR

7 LTR10B.ERV1.LTR.70.[433] 4.51E−01 794 K.repcat.e.2008.body.300.MER

27 MER34D.ERV1.LTR.339.[322] 4.51E−01 795 K.repcat.e.2008.body.300.MER

26 MER51E.ERV1.LTR.240.[301] 4.51E−01 796 K.repcat.e&g.2008.body.300.A

270 AluJo/FLAM.Alu.SINE.2189.[11

4.63E−01 797 K.repcat.e&g.2008.body.300.M

2 MER67A-int.ERV1.LTR.18.[278] 4.63E−01 798 K.repcat.e&g.2008.body.300.t

9 tRNA-Glu- 4.63E−01 799 K.repcat.e.2008.body.300.LTR

205 LTR13.ERVK.LTR.458.[836] 4.63E−01 800 K.repcat.e.2008.body.300.MER

53 MER93a.ERV1.LTR.311.[247] 4.63E−01 801 K.repcat.e&g.2008.body.300.M

11 MER88.ERVL.LTR.110.[327] 4.74E−01 802 K.repcat.e.2008.body.300.MER

32 MER101.ERV1.LTR.379.[292] 4.74E−01 803 K.repcat.e.2008.body.300.MER

59 MER90.ERV1.LTR.678.[317] 4.74E−01 804 K.repcat.e&g.2008.body.300.H

16 HERVK13.ERVK.LTR.64.[1278] 4.86E−01 805 K.repcat.e.2008.body.300.MER

56 MER67B.ERV1.LTR.438.[353] 4.98E−01 806 K.repcat.e&g.2008.body.300.H

192 HERVE.ERV1.LTR.346.[2130] 5.11E−01 807 K.repcat.e&g.2008.body.300.M

31 MER45R.Tip100.DNA.260.[525] 5.11E−01 808 K.repcat.e.2008.body.300.LTR

16 LTR25.ERV1.LTR.261.[466] 5.11E−01 809 K.repcat.e&g.2008.body.300.T

27 Tigger5c.MER2_type.DNA.939.[

5.23E−01 810 K.repcat.e&g.2008.body.300.M

67 MER106B.MER1_type.DNA.839.[1

5.35E−01 811 K.repcat.e&g.2008.body.300.M

1 MER34D-int.ERV1.LTR.24.[999] 5.35E−01 812 K.repcat.e&g.2008.body.300.M

45 MER106A.MER1_type.DNA.689.[1

5.48E−01 813 K.repcat.e&g.2008.body.300.G

73 GSATII.centr.Satellite.157.[

5.61E−01 814 K.repcat.e&g.2008.body.300.H

27 HERV15.ERV1.LTR.116.[1879] 5.61E−01 815 K.repcat.e&g.2008.body.300.M

93 MER48.ERV1.LTR.192.[361] 5.61E−01 816 K.repcat.e.2008.body.300.HER

48 HERV3.ERV1.LTR.256.[1560] 5.61E−01 817 K.repcat.e&g.2008.body.300.L

7 LTR46-int.ERV1.LTR.67.[1415] 5.74E−01 818 K.repcat.e&g.2008.body.300.M

216 MER91A.Tip100.DNA.3430.[124] 5.74E−01 819K.repcat.e&g.2008.body.300.U

24 U7.snRNA.snRNA.246.[54] 5.87E−01 820 K.repcat.e.2008.body.300.Alu

30 AluYg.Alu.SINE.111.[105] 5.87E−01 821 K.repcat.e.2008.body.300.LTR

40 LTR34.ERV1.LTR.361.[370] 5.87E−01 822 K.repcat.e&g.2008.body.300.H

10 HY4.scRNA.scRNA.157.[79] 6.00E−01 823 K.repcat.e&g.2008.body.300.t

2 tRNA-Arg- 6.00E−01 824 K.repcat.e&g.2008.body.300.H

60 HERVFH21.ERV1.LTR.183.[962] 6.14E−01 825 K.repcat.e&g.2008.body.300.t

12 tRNA-Gly- 6.14E−01 826 K.repcat.e&g.2008.body.300.F

19 FordPrefect_a.Tip100.DNA.398

6.27E−01 827 K.repcat.e&g.2008.body.300.S

236 SATR1.Satellite.Satellite.42

6.27E−01 828 K.repcat.e.2008.body.300.LTR

28 LTR24.ERV1.LTR.308.[302] 6.27E−01 829 K.repcat.e&g.2008.body.300.L

1 LTR24C-int.ERV1.LTR.46.[510] 6.41E−01 830 K.repcat.e&g.2008.body.300.L

16 LTR61.ERV1.LTR.149.[398] 6.41E−01 831 K.repcat.e&g.2008.body.300.M

243 MER45A.Tip100.DNA.3214.[141] 6.41E−01 832K.repcat.e&g.2008.body.300.M

28 MER51C.ERV1.LTR.180.[396] 6.41E−01 833 K.repcat.e.2008.body.300.LTR

19 LTR14.ERVK.LTR.83.[463] 6.41E−01 834 K.repcat.e&g.2008.body.300.O

1653 Other 6.68E−01 835 K.repcat.e&g.2008.body.300.S

1653 SVA 6.68E−01 836 K.repcat.e.2008.body.300.LTR

5 LTR5.ERVK.LTR.23.[192] 6.68E−01 837 K.repcat.e&g.2008.body.300.M

13 MER51D.ERV1.LTR.148.[239] 6.82E−01 838 K.repcat.e&g.2008.body.300.M

35264 MIR.MIR.SINE.203898.[147] 6.82E−01 839K.repcat.e&g.2008.body.300.t

2 tRNA-Met-i.tRNA.tRNA.38.[60] 6.82E−01 840 K.repcat.e&g.2008.body.300.L

4 LTR60-int.ERV1.LTR.19.[368] 6.96E−01 841 K.repcat.e.2008.body.300.U13

9 U13.snRNA.snRNA.178.[98] 6.96E−01 842 K.repcat.e&g.2008.body.300.L

2 LTR38B-int.ERV1.LTR.18.[385] 7.10E−01 843 K.repcat.e&g.2008.body.300.M

66 MER91B.Tip100.DNA.1429.[105] 7.10E−01 844K.repcat.e.2008.body.300.LTR

71 LTR6A.ERV1.LTR.260.[460] 7.10E−01 845 K.repcat.e&g.2008.body.300.F

48 FRAM/FAM.Alu.SINE.530.[68] 7.25E−01 846 K.repcat.e&g.2008.body.300.L

1 LTR30-int.ERV1.LTR.7.[1505] 7.25E−01 847 K.repcat.e&g.2008.body.300.L

44 LTR6B.ERV1.LTR.149.[506] 7.25E−01 848 K.repcat.e&g.2008.body.300.M

11 MER51A- 7.25E−01 849 K.repcat.e&g.2008.body.300.M

28 MER63B.AcHobo.DNA.544.[368] 7.25E−01 850 K.repcat.e&g.2008.body.300.H

20 HERVFH19.ERV1.LTR.135.[947] 7.39E−01 851 K.repcat.e&g.2008.body.300.H

4 HERVL-B3.ERVL.LTR.93.[1286] 7.39E−01 852 K.repcat.e&g.2008.body.300.L

24844 L2.L2.LINE.403973.[230] 7.39E−01 853 K.repcat.e&g.2008.body.300.M

17373 MIRb.MIR.SINE.278083.[144] 7.39E−01 854K.repcat.e&g.2008.body.300.t

13 tRNA-Cys- 7.39E−01 855 K.repcat.e.2008.body.300.MER

100 MER31A.ERV1.LTR.1316.[321] 7.39E−01 856 K.repcat.e&g.2008.body.300.L

19 LTR21A.ERV1.LTR.89.[418] 7.53E−01 857 K.repcat.e.2008.body.300.LTR

13 LTR70.ERV1.LTR.128.[673] 7.53E−01 858 K.repcat.e&g.2008.body.300.D

18 D20S16.Satellite.Satellite.2

7.68E−01 859 K.repcat.e&g.2008.body.300.L

31 LTR10D.ERV1.LTR.189.[431] 7.68E−01 860 K.repcat.e&g.2008.body.300.L

3 LTR10G- 7.68E−01 861 K.repcat.e&g.2008.body.300.L

27 LTR47B.ERVL.LTR.380.[336] 7.68E−01 862 K.repcat.e&g.2008.body.300.M

10 MER4A-int.ERV1.LTR.120.[826] 7.68E−01 863K.repcat.e&g.2008.body.300.R

10 Ricksha_b.MuDR.DNA.115.[592] 7.97E−01 864K.repcat.e&g.2008.body.300.M

1 MER65D-int.ERV1.LTR.77.[587] 8.12E−01 865 K.repcat.e&g.2008.body.300.t

11 tRNA-Lys- 8.12E−01 866 K.repcat.e&g.2008.body.300.H

58 HERVH48.ERV1.LTR.115.[1792] 8.27E−01 867 K.repcat.e&g.2008.body.300.H

83 HERVS71.ERV1.LTR.149.[1952] 8.27E−01 868 K.repcat.e&g.2008.body.300.M

5 MER41D-int.ERV1.LTR.68.[425] 8.27E−01 869 K.repcat.e&g.2008.body.300.M

116 MER74A.ERVL.LTR.1526.[372] 8.27E−01 870 K.repcat.e.2008.body.300.Alu

5 AluYc.Alu.SINE.50.[73] 8.27E−01 871 K.repcat.e&g.2008.body.300.M

7 MER66-int.ERV1.LTR.249.[529] 8.56E−01 872 K.repcat.e.2008.body.300.MER

1109 MER20.MER1_type.DNA.16178.[1

8.71E−01 873 K.repcat.e&g.2008.body.300.L

2 LTR1B-int.ERV1.LTR.11.[2238] 8.86E−01 874 K.repcat.e&g.2008.body.300.s

296 snRNA 8.86E−01 875 K.repcat.e&g.2008.body.300.T

4 Tigger6b.MER2_type.DNA.96.[4

8.86E−01 876 K.repcat.e&g.2008.body.300.M

21 MER58D.MER1_type.DNA.282.[25

9.01E−01 877 K.repcat.e&g.2008.body.300.T

40 TAR1.telo.Satellite.123.[482

9.17E−01 878 K.repcat.e&g.2008.body.300.t

3 tRNA-Gln- 9.17E−01 879 K.repcat.e&g.2008.body.300.5

107 5S.rRNA.rRNA.1258.[70] 9.32E−01 880 K.repcat.e&g.2008.body.300.L

19 LTR31.ERV1.LTR.249.[407] 9.32E−01 881 K.repcat.e&g.2008.body.300.L

2 LTR6A-int.ERV1.LTR.15.[542] 9.32E−01 882 K.repcat.e&g.2008.body.300.L

28 LTR71B.ERV1.LTR.209.[426] 9.32E−01 883 K.repcat.e&g.2008.body.300.r

107 rRNA 9.32E−01 884 K.repcat.e.2008.body.300.Alu

9 AluYh.Alu.SINE.23.[120] 9.32E−01 885 K.repcat.e.2008.body.300.MER

35 MER52C.ERV1.LTR.366.[827] 9.32E−01 886 K.repcat.e&g.2008.body.300.M

54 MER121.Unknown.Unknown.919.[

9.47E−01 887 K.repcat.e&g.2008.body.300.U

10 U4.snRNA.snRNA.161.[92] 9.47E−01 888 K.repcat.e.2008.body.300.Unk

54 Unknown 9.47E−01 889 K.repcat.e&g.2008.body.300.L

7 LOR1a-int.ERV1.LTR.215.[673] 9.62E−01 890 K.repcat.e&g.2008.body.300.t

2 tRNA-Val- 9.77E−01 891 K.repcat.e.2008.body.300.LTR

27 LTR10B1.ERV1.LTR.242.[314] 9.77E−01 892 K.repcat.e&g.2008.body.300.C

569 Charlie8.MER1_type.DNA.7585.

9.92E−01 893 K.repcat.e&g.2008.body.300.G

25 GSATX.centr.Satellite.58.[17

9.92E−01 894 K.repcat.e&g.2008.body.300.L

4 LTR7A.ERV1.LTR.16.[122] 9.92E−01 895 K.repcat.e&g.2008.body.300.M

91 MER90a.ERV1.LTR.1165.[326] 9.92E−01 896 K.repcat.e&g.2008.body.300.t

1 tRNA-SeC(e)- 9.92E−01 897 K.repcat.e.2008.body.300.LTR

15 LTR72.ERV1.LTR.149.[355] 9.92E−01 898 K.repcat.e.2008.body.300.tRN

1 tRNA-Thr- 9.92E−01

indicates data missing or illegible when filed

Next, statistical analysis was performed using random forest binarydecision trees. Table 6 shows the importance of top 45 from 139,379variables generated using Random Forest algorithm. The categoriesinclude gene probes (gene), non-genic and non-repetitive probes(nonrep), repetitive element. The random forest classifier based on therepetitive element categories alone worked well (89% accuracy). Bothalgorithms agree on several categories of repetitive elements being themost informative, i.e. both algorithms report them in the top 20, forexample: MER67D, HUERS-P3B, MER6, MER66C, ERVL, MLT1G1, MLT2D, MER50B,THE1B (Table 5 and Table 7). In both analyses, the categories based onthe primer design discussed in recent literature ranked much lower i.e.˜200 (Table 5, Wilcoxon) or ˜350 (Table 7, Random Forest) than thecategories defined based on repetitive elements.

TABLE 6 Importance of top 45 from 139,379 variables generated usingRandom Forest algorithm. The categories include gene probes (gene),non-genic and non-repetitive probes (nonrep), repetitive element(description includes name, class and family of a repetitive elementaccording to RepBase, count of a repeat in the genome and [averagelength]). The ranking is based on the average decrease in classificationaccuracy if the variables are randomly permuted one at a time. ThemeanMargin and meanTumor columns show the methylation level in categoryamong Non-Tumor Adjacent and Tumor experiments respectively. Columns 1(Normal), 2 (Non-Tumor Adjacent), and 3 (Tumor) indicate the decrease inthe prediction accuracy per category in a given subset of experimentsduring the cross validation. MeanDecreaseAccuracy is an average decreaseof overall accuracy of classification. MeanDecreaseGini indicatesaverage decrease in Gini statistic (summarized in the ROC in FIG. 4).Importance of top 45 variables (total 139379 Variables) Num Mean MeanMean Decrease Probe Margin Tumor 1 2 3 Accuracy nonrep.122208 1 −0.713−4.307 6.616 5.741 4.621 3.387 nonrep.122209 1 −0.389 −3.732 5.687 4.7063.919 2.843 MER6.MER2_type.DNA.926.(416) 1995 0.041 0.13 5.432 4.3543.857 2.788 HUERS-P3b.ERV1.LTR.378.(917) 28 0.292 0.517 5.96 4.247 3.7612.743 MER66C.ERV1.LTR.661.(279) 54 0.063 0.217 5.685 4.446 3.622 2.673MER67D.ERV1.LTR.1130.(294) 49 0.21 0.411 5.575 3.094 3.687 2.637ERVL.ERVL.LTR.826.(422) 6129 0.119 0.212 5.277 3.808 3.389 2.511MER4D.ERV1.LTR.1275.(421) 247 0.081 0.171 5.476 2.978 3.199 2.336MLT1A1.MaLR.LTR.6611.(294) 321 0.094 0.209 5.221 3.786 3.116 2.334MLT1G1.MaLR.LTR.4437.(320) 247 0.069 0.182 4.424. 3.43 3.08 2.298MLT2B3.ERVL.LTR.2966.(406) 132 0.244 0.424 5.356 1.891 3.161 2.295nonrep.303433 1 0.247 −2.016 1.695 3.929 3.109 2.29MLT2D.ERVL.LTR.4035.(266) 174 0.121 0.218 4.386 2.862 3.224 2.273body.LTR 38991 0.178 0.272 5.166 2.442 3.024 2.263 body.MaLR 15574 0.1260.215 4.747 2.685 3.128 2.259 gene.122206 1 0.382 −2.091 4.592 3.8422.985 2.251 gene.122207 1 −1.391 −3.43 4.732 3.499 3.059 2.225nonrep.122204 1 −1.093 −4.179 3.721 2.97 2.958 2.214 non rep.70135 1−1.109 −1.717 4.871 1.954 2.992 2.212 nonrep.147762 1 −0.068 −1.766 3.673.441 2.836 2.128 THE1B.MaLR.LTR.22106.(329) 719 0.316 0.461 5.404 2.2012.843 2.122 gene.54663 1 0.336 −2.149 2.139 3.89 2.681 2.095 gene.2986791 −1.309 −2.11 4.702 3.006 2.702 2.079 gene.232740 1 −0.143 −1.737 3.6712.961 2.848 2.071 nonrep.154468 1 1.317 −1.228 −0.708 3.816 2.708 2.056gene.70781 1 0.211 −1.791 2.582 3.684 2.715 2.03MLT1A.MaLR.LTR.8650.(280) 1783 0.107 0.215 4.085 2.908 2.76 2.014MLT2B2.ERVL.LTR.2019.(335) 91 −0.07 0.1 −0.36 3.804 2.577 1.993MER50B.ERV1.LTR.681.(468) 102 0.073 0.262 3.091 3.004 2.722 1.992gene.232742 1 −0.485 −2.134 3.006 3.569 2.631 1.99 gene.91801 1 −0.765−1.878 4.05 2.18 2.762 1.974 MSTC.MaLR.LTR.3115.(284) 211 0.183 0.2884.606 1.849 2.72 1.968 HUERS-P3.ERV1.LTR.841.(806) 94 0.322 0.466 4.7421.514 2.745 1.913 nonrep.149154 1 −0.146 −2.955 2.345 3.309 2.475 1.907nonrep.122203 1 −1.072 −3.291 4.015 2.941 2.528 1.887 gene.39459 1 0.909−1.149 1.138 3.194 2.581 1.883 gene.63060 1 −0.415 −2.355 3.746 3.1552.508 1.874 MER50.ERV1.LTR.2576.(431) 408 0.233 0.36 4.03 2.436 2.3681.874 MLT1G.MaLR.LTR.3459.(318) 453 0.09 0.172 4.247 2.137 2.53 1.848MLT1A0.MaLR.LTR.20156.(279) 1043 0.114 0.218 4.584 1.589 2.482 1.825gene.38409 1 −1.687 −2.625 4.028 1.615 2.493 1.822MER51B.ERV1.LTR.697.(303) 90 0.163 0.289 4.171 2.587 2.399 1.815MLT1E.MaLR.LTR.3378.(359) 649 0.046 0.157 3.127 2.524 2.388 1.806nonrep.153897 1 −0.68 −2.597 3.277 2.802 2.512 1.803 gene.248283 1−1.003 −2.526 3.77 2.981 2.326 1.779 Random Forest to Classify Normal,Margin and Tumor (Genes + NonRep. + Rep.[Body Only], 139379 vars)

TABLE 7 Importance of 901 repetitive element and literature basedvariables. Repetitive element categories and 5 categories defined basedon literature, ranked based on the decreased mean accuracy inclassification using Random Forest. The meanMargin and meanTumor columnsshow the methylation level in category among Non-Tumor Adjacent andTumor experiments respectively. Columns 1 (Normal), 2 (Non-TumorAdjacent), and 3 (Tumor) indicate the decrease in the predictionaccuracy per category in a given subset of experiments during the crossvalidation. MeanDecreaseAccuracy is an average decrease of overallaccuracy of classification. MeanDecreaseGini indicates average decreasein Gini statistic. The 5 categories defined in the literature arehighlighted in bold. Mean Mean mean mean Decrease Decrease rankdescription of category count Margin Tumor 1 2 3 Accuracy Gini 1MER67D.ERV1.LTR.1130.[294] 49 0.21 0.41 17.6 5.9 15.0 10.52 1.26 2HUERS- 28 0.29 0.52 24.9 13.0 14.2 10.30 2.04 3 MER6.MER2_type.DNA.926.[41

1995 0.04 0.13 23.9 14.8 13.3 10.01 2.04 4 MER66C.ERV1.LTR.661.[279] 540.06 0.22 22.5 15.1 12.7 9.56 1.84 5 ERVL.ERVL.LTR.826.[422] 6129 0.120.21 18.4 10.8 9.2 7.52 1.23 6 MLT1G1.MaLR.LTR.4437.[320] 247 0.07 0.1812.6 8.5 7.8 6.07 0.78 7 MER41E- 1 2.73 2.40 15.0 9.8 −0.9 5.79 0.43 8MER4D.ERV1.LTR.1275.[421] 247 0.08 0.17 13.7 6.0 7.4 5.78 0.68 9MLT2D.ERVL.LTR.4035.[266] 174 0.12 0.22 12.1 6.8 7.5 5.68 0.68 10Charlie5.MER1_type.DNA.346 261 −0.19 −0.15 14.1 8.2 0.0 5.29 0.37 11body.LTR 38991 0.18 0.27 13.7 4.3 6.6 5.28 0.60 12MLT1A1.MaLR.LTR.6611.[294] 321 0.09 0.21 12.5 7.3 6.8 5.25 0.58 13HUERS- 94 0.32 0.47 12.2 2.9 6.5 5.08 0.47 14 Cheshire.MER1_type.DNA.74766 −0.27 −0.14 11.2 8.2 −0.7 4.45 0.27 15 HERVL.ERVL.LTR.1081.[547] 2380.15 0.30 7.9 2.6 5.9 4.25 0.35 16 LTR19C- 5 −0.56 −0.63 3.7 −4.1 6.84.23 0.11 17 MER70A.ERVL.LTR.524.[386] 39 0.14 0.31 10.1 3.6 5.5 4.210.37 18 MER50B.ERV1.LTR.681.[468] 102 0.07 0.26 8.3 5.3 5.4 4.15 0.33 19MER51B.ERV1.LTR.697.[303] 90 0.16 0.29 9.9 5.8 5.1 4.08 0.36 20THE1B.MaLR.LTR.22106.[329] 719 0.32 0.46 11.2 2.6 4.3 4.07 0.29 21LTR7A.ERV1.LTR.16.[122] 4 1.32 1.30 11.0 5.9 −0.6 4.07 0.22 22MLT2B3.ERVL.LTR.2966.[406] 132 0.24 0.42 11.0 1.5 4.8 4.03 0.32 23MER52C- 1 1.94 1.62 10.8 6.1 −0.8 3.94 0.21 24 MER11B.ERVK.LTR.552.[932]41 0.73 0.94 10.7 4.6 2.0 3.93 0.23 25 LTR52.ERVL.LTR.1035.[277] 69 0.290.31 10.9 4.6 −0.2 3.91 0.20 26 Charlie3.MER1_type.DNA.639 57 −0.03 0.112.8 4.3 5.2 3.91 0.20 27 body.MaLR 15574 0.13 0.22 10.0 3.3 4.8 3.910.33 28 tRNA-Pro- 3 0.28 0.19 0.9 4.8 5.2 3.83 0.12 29 THE1- 14 0.851.25 5.9 1.5 4.7 3.79 0.14 30 LTR10B.ERV1.LTR.70.[433] 43 0.42 0.40 10.34.8 −0.9 3.74 0.20 31 MER50.ERV1.LTR.2576.[431] 408 0.23 0.36 10.4 4.03.3 3.72 0.26 32 LTR14B.ERVK.LTR.358.[464] 59 0.50 0.75 10.0 4.6 0.83.66 0.17 33 LTR22.ERVK.LTR.103.[478] 88 0.16 0.33 8.5 5.9 3.5 3.57 0.2834 HUERS- 32 0.14 0.27 3.8 1.5 4.8 3.53 0.13 35MER92B.ERV1.LTR.870.[297] 72 0.36 0.38 9.4 5.1 −0.3 3.45 0.16 36LTR9B.ERV1.LTR.745.[398] 135 0.50 0.64 9.5 3.6 0.6 3.45 0.15 37MSTC.MaLR.LTR.3115.[284] 211 0.18 0.29 9.0 2.4 4.5 3.45 0.24 38LTR2.ERV1.LTR.847.[415] 1075 0.23 0.34 8.6 3.5 2.6 3.44 0.16 39LTR21B.ERV1.LTR.58.[342] 10 0.88 0.77 9.4 5.5 −0.3 3.44 0.15 40PABL_A.ERV1.LTR.514.[471] 62 −0.03 0.07 0.5 3.3 4.5 3.31 0.09 41MSTD.MaLR.LTR.7421.[291] 365 0.25 0.36 8.9 3.7 2.0 3.28 0.17 42LTR77.ERV1.LTR.149.[430] 7 0.53 0.78 8.4 3.4 2.6 3.24 0.22 43LTR33A.ERVL.LTR.3521.[226] 174 0.13 0.22 5.5 1.2 4.0 3.16 0.10 44LTR8.ERV1.LTR.3520.[439] 486 0.27 0.36 8.7 3.5 1.6 3.15 0.12 45HERVFH21.ERV1.LTR.183.[962

60 0.90 0.77 9.0 5.2 −0.3 3.15 0.13 46 MLT1G.MaLR.LTR.3459.[318] 4530.09 0.17 7.6 2.2 4.2 3.14 0.16 47 MLT2B2.ERVL.LTR.2019.[335] 91 −0.070.10 −1.3 6.3 4.2 3.13 0.22 48 LTR38C.ERV1.LTR.132.[373] 13 0.52 0.668.9 3.6 0.7 3.12 0.13 49 MER11A.ERVK.LTR.930.[920] 43 0.66 0.98 7.1 1.63.6 3.11 0.13 50 MER66- 7 0.87 0.88 8.8 2.7 −0.1 3.06 0.12 51 MER70- 70.90 0.98 8.3 3.3 0.4 3.03 0.13 52 LTR19B- 4 0.76 0.72 8.5 3.3 0.3 2.990.12 53 LTR8A.ERV1.LTR.2663.[482] 154 0.31 0.38 8.8 2.6 1.1 2.98 0.12 54MER34C.ERV1.LTR.257.[221] 89 −0.04 −0.01 −0.6 0.8 4.8 2.98 0.08 55MER51A.ERV1.LTR.953.[414] 104 0.30 0.33 8.6 2.5 0.9 2.97 0.12 56MER92A.ERV1.LTR.145.[271] 12 0.48 0.61 8.2 3.6 −0.0 2.95 0.11 57MER115.Tip100.DNA.2382.[29

141 0.15 0.17 8.5 3.6 0.2 2.95 0.11 58 L1PA10.L1.LINE.6962.[920] 3420.33 0.52 8.4 1.7 1.1 2.95 0.12 59 MSTB- 34 0.61 0.80 8.5 2.8 1.6 2.940.11 60 LTR48.ERV1.LTR.1227.[342] 127 0.27 0.33 8.1 3.8 −0.1 2.90 0.1061 MSTB1.MaLR.LTR.4879.[326] 224 0.34 0.45 8.3 3.5 1.1 2.90 0.11 62LTR21A.ERV1.LTR.89.[418] 19 0.98 0.95 8.5 3.5 −0.1 2.88 0.11 63MSTA.MaLR.LTR.19102.[319] 904 0.36 0.50 8.3 2.2 1.5 2.87 0.11 64MSTB.MaLR.LTR.8397.[321] 777 0.33 0.45 8.0 2.1 1.1 2.86 0.11 65 LOR1a- 70.66 0.65 8.2 3.6 −0.3 2.85 0.11 66 MER83C- 3 1.34 1.49 8.3 2.8 0.5 2.840.11 67 Kanga1a.Tc2.DNA.310.[392] 27 0.25 0.29 8.0 3.6 0.7 2.83 0.10 68LTR19A.ERV1.LTR.417.[359] 37 0.29 0.37 8.3 2.8 0.1 2.81 0.11 69 LTR43- 9−0.31 −0.18 1.1 5.2 2.7 2.81 0.10 70 body.AcHobo 997 0.02 0.08 4.3 3.63.7 2.81 0.14 71 LTR36.ERV1.LTR.474.[382] 50 0.18 0.30 5.2 2.1 3.6 2.810.17 72 MLT1A.MaLR.LTR.8650.[280] 1783 0.11 0.21 7.1 3.7 3.2 2.79 0.1773 MER11D.ERVK.LTR.259.[745] 37 0.68 1.04 6.3 1.5 2.1 2.78 0.11 74body.ERV 24732 0.21 0.31 6.8 3.0 1.9 2.76 0.12 75 LTR25- 13 0.51 0.608.0 1.8 1.2 2.76 0.11 76 LTR25.ERV1.LTR.261.[466] 28 0.50 0.57 7.8 2.4−0.7 2.74 0.11 77 THE1C.MaLR.LTR.9731.[329] 349 0.34 0.51 7.9 0.2 1.82.73 0.15 78 MER4A1.ERV1.LTR.2150.[358] 257 0.18 0.29 7.5 1.3 2.7 2.690.13 79 LTR5A.ERVK.LTR.250.[947] 34 0.60 0.68 4.3 1.7 3.0 2.65 0.06 80MER4D1.ERV1.LTR.1393.[464] 110 0.17 0.25 7.2 1.2 2.4 2.61 0.12 81HY1.scRNA.scRNA.428.[97] 43 −0.20 −0.13 6.9 4.2 −0.9 2.53 0.09 82THE1A.MaLR.LTR.4161.[319] 170 0.37 0.52 7.1 1.0 −0.0 2.47 0.08 83 THE1A-25 0.36 0.56 7.3 1.4 −0.2 2.47 0.10 84 L1MA7.L1.LINE.7550.[459] 383 0.210.34 6.8 1.1 2.6 2.46 0.11 85 L1PB4.L1.LINE.6330.[529] 329 0.18 0.34 6.51.3 3.0 2.46 0.12 86 MLT2B1.ERVL.LTR.4186.[325] 169 0.14 0.31 6.6 2.03.0 2.44 0.13 87 MLT1E.MaLR.LTR.3378.[359] 649 0.05 0.16 4.5 4.1 2.72.44 0.14 88 MLT1E2.MaLR.LTR.3960.[377] 239 0.04 0.18 4.0 3.3 3.0 2.430.13 89 LTR10F.ERV1.LTR.432.[415] 93 0.74 0.93 6.8 1.2 0.3 2.40 0.08 90ERVL- 133 0.10 0.19 3.6 4.8 2.4 2.40 0.15 91 HERVL- 20 0.28 0.55 6.0 0.33.1 2.40 0.11 92 body.ERVK 1562 0.36 0.50 4.4 1.6 2.3 2.37 0.06 93LTR75_1.ERV1.LTR.129.[320] 14 −0.16 −0.01 −1.3 5.6 1.9 2.36 0.07 94PRIMA4_LTR.ERV1.LTR.344.[4

32 0.19 0.35 6.3 1.5 2.9 2.36 0.12 95 LTR10D.ERV1.LTR.189.[431] 31 0.430.42 6.2 3.0 0.4 2.36 0.08 96 LTR1B.ERV1.LTR.1147.[622] 110 0.42 0.595.3 −0.7 2.3 2.30 0.06 97 tRNA-Leu- 2 0.93 0.72 6.1 3.4 −0.1 2.28 0.0898 MER69A.Tip100.DNA.1046.[14

70 0.23 0.25 6.2 0.6 0.6 2.27 0.06 99 THE1D.MaLR.LTR.12381.[324] 5110.29 0.44 6.6 0.3 1.1 2.24 0.08 100 MER74A.ERVL.LTR.1526.[372] 116 0.330.30 6.0 3.2 −0.7 2.24 0.07 101 LTR14.ERVK.LTR.83.[463] 127 0.45 0.636.6 1.6 0.5 2.24 0.06 102 HERV16.ERVL.LTR.4493.[505] 186 0.11 0.23 5.50.5 2.9 2.23 0.09 103 MLT2B4.ERVL.LTR.4120.[305] 157 0.12 0.23 5.6 0.82.8 2.23 0.11 104 MER9.ERVK.LTR.1128.[475] 1496 0.09 0.13 5.6 1.8 1.02.19 0.06 105 MADE2.Mariner.DNA.2609.[69

119 −0.23 −0.18 5.0 3.7 0.5 2.19 0.07 106 LTR69.ERVL.LTR.140.[376] 30.86 0.71 6.2 2.3 −0.3 2.18 0.06 107 LTR10B1.ERV1.LTR.242.[314] 35 0.370.32 5.3 2.6 0.2 2.17 0.06 108 MER45B.Tip100.DNA.1173.[40

109 −0.12 −0.05 3.6 4.0 0.2 2.16 0.09 109 LTR9.ERV1.LTR.1919.[459] 4270.33 0.48 5.6 0.3 1.8 2.15 0.08 110 body.Unknown 108 0.54 0.54 6.1 2.0−0.8 2.14 0.07 111 MER11C.ERVK.LTR.825.[998] 138 0.49 0.69 5.8 0.6 1.32.12 0.06 112 HERVK9.ERVK.LTR.723.[1250] 77 0.90 1.22 5.6 1.0 1.5 2.090.06 113 body.ERV1 17661 0.23 0.33 5.6 1.8 1.6 2.07 0.09 114 HERVL- 440.62 0.93 3.1 −0.2 2.5 2.04 0.03 115 LTR34- 1 −0.86 −0.59 5.2 3.0 −0.32.01 0.10 116 MLT- 139 0.46 0.63 6.2 −0.9 0.5 2.00 0.06 117 body.SVA1653 0.59 0.62 5.9 0.6 0.1 1.99 0.06 118 LTR3.ERVK.LTR.83.[383] 13880.15 0.23 4.5 0.6 2.1 1.97 0.05 119 MLT1A0.MaLR.LTR.20156.[279

1043 0.11 0.22 4.9 1.6 2.2 1.95 0.07 120 MER4E.ERV1.LTR.694.[476] 1580.18 0.22 6.2 −0.4 −0.0 1.94 0.07 121 L1PA8.L1.LINE.7715.[856] 479 0.330.52 5.8 −0.0 1.0 1.94 0.04 122 MER58B.MER1_type.DNA.6800.

490 −0.11 −0.05 4.2 3.8 −0.0 1.94 0.07 123 LTR10A.ERV1.LTR.301.[449] 290.39 0.49 4.7 1.5 1.3 1.92 0.05 124 GSATII.centr.Satellite.157

73 −0.34 −0.31 5.9 −0.1 −0.2 1.92 0.06 125 Tigger2a.MER2_type.DNA.320

218 0.19 0.26 5.1 1.2 −0.2 1.92 0.05 126 MLT2A1.ERVL.LTR.3220.[327] 970.42 0.56 5.8 −0.1 −0.5 1.91 0.06 127 body.rRNA 107 0.16 0.16 4.9 2.5−0.4 1.90 0.05 128 MER61A.ERV1.LTR.791.[303] 111 0.14 0.26 4.1 2.5 1.01.89 0.05 129 MER74B.ERVL.LTR.936.[328] 80 0.27 0.32 5.8 −0.9 0.5 1.890.06 130 body.Other 1653 0.59 0.62 5.7 −0.2 0.4 1.88 0.05 131LTR7B.ERV1.LTR.861.[364] 137 0.42 0.57 4.9 1.7 0.9 1.88 0.04 132 MER66A-3 −0.38 0.02 1.1 2.6 1.9 1.87 0.05 133 FordPrefect.Tip100.DNA.410

45 −0.13 −0.10 4.2 3.0 −0.2 1.87 0.06 134 MLT1F.MaLR.LTR.4498.[327] 7260.03 0.12 2.9 2.4 2.4 1.87 0.07 135 LTR54B.ERV1.LTR.832.[289] 53 −0.050.09 0.7 1.7 2.4 1.86 0.05 136 MER41A.ERV1.LTR.2479.[384] 246 0.06 0.173.2 2.8 2.0 1.85 0.08 137 THE1B- 46 0.39 0.64 4.8 0.5 1.3 1.84 0.04 138L1MA1.L1.LINE.3940.[1012] 494 0.11 0.27 4.8 1.7 2.2 1.83 0.07 139LTR14A.ERVK.LTR.113.[329] 19 0.87 1.07 4.6 1.5 1.1 1.83 0.05 1405S.rRNA.rRNA.1258.[70] 107 0.16 0.16 4.8 2.5 −0.2 1.83 0.05 141LTR16A1.ERVL.LTR.3898.[252

197 0.13 0.19 4.0 2.7 0.9 1.83 0.04 142 HSMAR1.Mariner.DNA.703.[66

100 0.19 0.46 4.3 2.8 1.9 1.81 0.07 143 MER73.ERVL.LTR.270.[408] 22 0.460.53 5.6 −1.9 0.7 1.80 0.05 144 LTR16A.ERVL.LTR.6873.[276] 510 0.14 0.215.1 −0.3 1.4 1.79 0.05 145 MER110.ERV1.LTR.736.[250] 83 0.06 0.17 3.11.3 2.5 1.79 0.07 146 LTR5B.ERVK.LTR.420.[781] 111 0.44 0.51 3.4 0.5 1.81.77 0.04 147 LTR7Y.ERV1.LTR.472.[361] 102 0.34 0.56 2.8 −0.8 2.4 1.770.03 148 ERVL- 22 0.29 0.41 4.9 0.1 0.9 1.76 0.04 149LOR1a.ERV1.LTR.789.[380] 28 0.39 0.45 5.2 1.0 −0.9 1.75 0.05 150LTR41.ERVL.LTR.2357.[234] 134 0.05 0.14 1.1 1.3 2.5 1.74 0.02 151LTR5.ERVK.LTR.23.[192] 851 0.14 0.22 3.8 −0.3 1.9 1.74 0.03 152PABL_B.ERV1.LTR.361.[373] 36 0.26 0.29 4.2 1.3 0.6 1.74 0.04 153LTR12B.ERV1.LTR.450.[875] 80 0.47 0.62 4.9 0.9 1.0 1.74 0.05 154LTR22A.ERVK.LTR.187.[402] 15 0.09 0.28 1.5 2.8 1.9 1.72 0.04 155 MLT1E-5 −0.00 −0.14 −0.5 1.4 2.6 1.72 0.02 156 LTR38.ERV1.LTR.313.[381] 610.19 0.31 4.3 −0.9 1.4 1.71 0.03 157 HERVI.ERV1.LTR.124.[2141] 181 0.390.50 4.2 0.6 1.3 1.68 0.04 158 MLT2A2.ERVL.LTR.3754.[411] 136 0.31 0.524.3 0.6 1.6 1.68 0.05 159 MLT1J.MaLR.LTR.15375.[246] 1277 0.02 0.09 2.91.9 2.4 1.66 0.06 160 MER66C- 10 0.22 0.50 3.8 0.3 2.0 1.65 0.05 161HERVP71A.ERV1.LTR.190.[134

38 0.40 0.51 4.5 1.1 −0.4 1.64 0.04 162 L1M2b.L1.LINE.318.[858] 12 0.380.52 4.4 0.2 0.7 1.61 0.03 163 L1PA11.L1.LINE.3886.[997] 193 0.40 0.644.5 −1.0 0.7 1.59 0.04 164 MER31A.ERV1.LTR.1316.[321] 110 0.14 0.13 3.42.3 0.4 1.59 0.04 165 LTR22C.ERVK.LTR.378.[442] 41 0.24 0.43 4.5 0.7 1.71.58 0.07 166 MLT2F.ERVL.LTR.1917.[323] 114 0.11 0.19 4.3 1.4 1.5 1.580.05 167 LTR38B- 2 1.18 1.29 4.5 −0.3 0.3 1.57 0.03 168 MLT1E2- 2 −0.93−0.51 3.3 2.5 0.9 1.57 0.04 169 MER63C.AcHobo.DNA.602.[467

56 −0.21 −0.13 2.8 2.9 0.0 1.56 0.04 170 LTR1D.ERV1.LTR.978.[707] 980.39 0.54 5.1 −0.8 1.4 1.56 0.05 171 LTR1.ERV1.LTR.1396.[612] 6740 0.330.42 4.7 0.5 0.6 1.55 0.04 172 MER34D.ERV1.LTR.339.[322] 28 0.41 0.374.0 1.3 −0.2 1.55 0.04 173 MER63A.AcHobo.DNA.2791.[18

127 0.06 0.16 2.8 1.3 2.1 1.55 0.04 174 THE1D- 27 0.55 0.73 4.4 −0.5 0.41.55 0.03 175 LTR3A.ERVK.LTR.158.[396] 37 0.43 0.58 3.7 0.2 1.2 1.550.03 176 body.snRNA 296 −0.11 −0.10 4.2 1.8 −0.3 1.54 0.06 177MER39.ERV1.LTR.3125.[336] 323 0.04 0.13 3.5 1.6 2.0 1.53 0.04 178MER4B.ERV1.LTR.1709.[402] 196 0.04 0.14 3.3 0.9 1.9 1.53 0.04 179MER63.AcHobo.DNA.3400.[139

500 −0.03 0.04 −1.0 3.2 1.5 1.53 0.02 180 MER91C.Tip100.DNA.1249.[92

44 −0.20 −0.16 4.0 1.9 −0.4 1.52 0.04 181 MER41B.ERV1.LTR.2864.[370] 267−0.03 0.08 −0.8 3.3 0.6 1.52 0.02 182 HERVK.SVA, ERVK.Other, LTR.3

454 0.36 0.53 3.3 0.4 1.2 1.52 0.02 183 LTR67.ERVL.LTR.6289.[175] 2860.08 0.15 3.5 −0.5 1.9 1.50 0.03 184 MER61E.ERV1.LTR.308.[387] 18 0.390.51 4.4 −0.2 0.2 1.49 0.03 185 ERVL-D.ERVL.LTR.249.[796] 11 0.15 0.393.3 1.6 1.7 1.48 0.06 186 L1MDb.L1.LINE.1862.[510] 135 0.19 0.28 4.3 1.0−0.5 1.48 0.03 187 U1.snRNA.snRNA.183.[129] 61 −0.12 −0.27 1.9 −0.0 2.31.47 0.02 188 HERV17.ERV1.LTR.919.[982] 107 0.77 0.92 4.2 0.1 0.7 1.450.03 189 body.LINE 79198 0.08 0.17 3.9 0.5 1.6 1.43 0.03 190L1MA9.L1.LINE.14394.[495] 729 0.17 0.33 4.6 −0.4 1.4 1.43 0.04 191 MSTD-34 0.37 0.63 3.7 0.6 0.8 1.42 0.02 192 LTR33.ERVL.LTR.9302.[253] 6590.17 0.24 4.0 −0.2 0.9 1.42 0.03 193 L1MB1.L1.LINE.5670.[521] 300 0.120.29 3.5 −0.0 1.7 1.42 0.03 194 MLT1H1.MaLR.LTR.3868.[316] 216 0.02 0.090.6 1.0 2.0 1.40 0.02 195 MER61A- 48 0.21 0.28 4.1 0.8 −0.0 1.40 0.03196 L1MA8.L1.LINE.9992.[497] 560 0.16 0.30 4.2 −0.9 1.5 1.40 0.04 197MSTA- 51 0.39 0.57 3.3 −0.3 1.1 1.40 0.02 198 MER41C.ERV1.LTR.799.[320]90 0.01 0.12 0.5 3.3 0.8 1.39 0.04 199 MLT1C- 17 −0.00 0.15 −0.6 0.0 2.31.39 0.04 200 MER4A.ERV1.LTR.1084.[386] 363 0.13 0.23 4.1 −0.3 0.9 1.390.03 201 tRNA-Ile- 10 0.09 −0.16 0.1 0.7 2.0 1.38 0.02 202 PRIMA41- 130.39 0.50 4.1 −0.2 0.0 1.37 0.03 203 MER1A.MER1_type.DNA.2968.[

299 0.13 0.17 1.8 −0.0 1.7 1.37 0.01 204 PRIMA4- 160 0.16 0.21 3.3 −0.10.8 1.36 0.03 205 MLT1H- 151 0.23 0.32 4.6 0.7 −0.3 1.36 0.04 206MSR1.Satellite.Satellite.3

118 0.29 0.04 3.0 2.0 0.3 1.36 0.02 207 MER94.AcHobo.DNA.4680.[105

199 0.09 0.15 3.4 −0.6 1.3 1.34 0.03 208 LTR7.ERV1.LTR.2349.[407] 9350.29 0.48 2.9 −0.7 1.4 1.34 0.02 209 MADE1.Mariner.DNA.7773.[61

348 −0.00 0.12 1.4 1.4 1.7 1.34 0.03 210 LOR1- 38 0.09 0.23 3.0 1.6 1.01.34 0.02 211 MER83.ERV1.LTR.435.[329] 77 0.14 0.23 1.9 −0.4 2.0 1.330.02 212 MLT1B- 13 −0.41 −0.22 2.5 2.6 −0.3 1.33 0.03 213L1MC4_3endX.L1.LINE.1031.[

73 −0.03 0.04 0.1 3.0 0.2 1.32 0.01 214 Tigger6b.MER2_type.DNA.96.

4 1.17 1.30 4.6 −0.6 −0.7 1.32 0.04 215 LTR76.ERV1.LTR.186.[480] 17 0.460.73 2.9 −0.3 1.6 1.31 0.02 216 L1PA7.L1.LINE.12334.[1556] 507 0.31 0.593.6 −0.3 1.0 1.31 0.02 217 tRNA-His- 10 0.63 −0.03 −0.1 1.6 1.8 1.310.02 218 LTR40a.ERVL.LTR.2060.[328] 108 −0.01 0.16 2.4 0.6 1.7 1.30 0.04219 MLT1F- 53 0.05 0.23 2.9 2.2 1.4 1.30 0.04 220L1P3b.L1.LINE.165.[1351] 14 0.42 0.62 3.8 0.3 0.7 1.30 0.02 221LTR27.ERV1.LTR.403.[558] 86 0.08 0.20 2.5 2.1 1.3 1.30 0.04 222MSTB2.MaLR.LTR.1595.[329] 64 0.22 0.37 3.1 0.4 1.1 1.29 0.02 223 MER67A-2 0.70 0.66 4.0 −1.2 0.3 1.29 0.03 224 MER7C.MER2_type.DNA.588.[3

49 0.09 0.14 1.4 −1.1 2.0 1.28 0.02 225 MLT1D.MaLR.LTR.19943.[325] 13550.11 0.17 2.2 1.4 1.0 1.25 0.02 226 tRNA-Ser- 5 0.41 0.33 0.9 −2.4 2.51.24 0.05 227 MER92C.ERV1.LTR.334.[159] 15 0.33 0.46 3.2 0.8 0.4 1.240.01 228 MLT1A1- 19 0.29 0.45 3.4 −0.3 1.1 1.24 0.02 229MER76.ERVL.LTR.674.[392] 50 0.13 0.24 2.6 0.8 1.0 1.24 0.02 230MER67A.ERV1.LTR.484.[249] 39 0.12 0.21 2.0 1.2 1.2 1.24 0.01 231HERVIP10F.ERV1.LTR.318.[14

151 0.39 0.50 3.2 −0.3 0.9 1.23 0.02 232 L1PA13.L1.LINE.10722.[840] 5130.33 0.57 3.5 0.1 0.9 1.23 0.02 233 MLT1E3.MaLR.LTR.1701.[338] 99 0.070.13 3.6 −0.5 1.5 1.23 0.03 234 MLT1A- 12 0.36 0.58 3.3 −0.1 1.2 1.220.02 235 MLT2B5.ERVL.LTR.461.[240] 16 0.36 0.47 4.0 −0.7 0.3 1.22 0.03236 LTR19B.ERV1.LTR.277.[423] 25 0.34 0.43 3.6 0.2 0.3 1.21 0.03 237LTR46.ERV1.LTR.231.[325] 39 0.24 0.40 3.2 −1.2 1.1 1.21 0.02 238HERV9.ERV1.LTR.1084.[1506] 148 0.90 1.06 3.2 −0.5 1.3 1.21 0.02 239LTR28.ERV1.LTR.513.[593] 30 0.24 0.28 2.9 1.2 0.2 1.21 0.02 240LTR47B.ERVL.LTR.380.[336] 27 −0.14 −0.16 0.7 0.0 2.0 1.21 0.01 241MER4E1.ERV1.LTR.1057.[396] 102 0.19 0.22 3.5 −0.6 −0.2 1.20 0.02 242MER57A.ERV1.LTR.2633.[290] 293 −0.01 0.11 1.0 1.2 1.6 1.19 0.04 243HUERS- 42 0.32 0.45 3.0 0.5 0.9 1.19 0.02 244 MER39- 8 0.23 0.30 1.4−0.8 1.5 1.18 0.02 245 L1MB3.L1.LINE.15139.[387] 1556 0.09 0.12 3.2 0.10.4 1.18 0.02 246 LTR1C.ERV1.LTR.242.[459] 32 0.35 0.47 3.1 0.1 0.4 1.160.01 247 tRNA-Pro- 2 0.26 −0.53 0.1 1.5 1.6 1.16 0.01 248LTR32.ERVL.LTR.1289.[281] 56 0.20 0.25 1.6 1.9 0.8 1.16 0.01 249SST1.centr.Satellite.565.[

126 0.05 −0.19 −0.6 1.4 1.5 1.16 0.01 250 PABL_B- 11 0.45 0.41 3.5 0.00.1 1.15 0.02 251 L1PA12.L1.LINE.2320.[1117] 136 0.37 0.62 3.3 −0.7 0.71.15 0.01 252 HERVIP10FH.ERV1.LTR.594.[1

87 0.52 0.60 2.2 0.2 1.0 1.15 0.01 253 MER63D.AcHobo.DNA.1023.[20

70 −0.18 −0.13 2.9 1.3 −0.2 1.14 0.03 254 L1MC1.L1.LINE.11868.[608] 8880.13 0.26 3.4 −0.5 0.8 1.14 0.02 255 MER39B.ERV1.LTR.1166.[382] 102 0.040.13 2.7 0.8 1.5 1.14 0.03 256 L1PA6.L1.LINE.5617.[1926] 291 0.32 0.553.0 −0.5 0.9 1.13 0.01 257 MLT1F1.MaLR.LTR.3489.[292] 204 −0.05 0.05−0.0 2.2 1.1 1.13 0.04 258 tRNA-Gly- 7 −0.32 −0.44 3.8 −0.3 0.3 1.130.03 259 LTR48B.ERV1.LTR.1058.[346] 56 0.23 0.28 3.4 −0.1 −0.0 1.12 0.02260 L1PA17.L1.LINE.4722.[700] 288 0.15 0.31 2.8 −0.4 1.0 1.12 0.01 261U13_.snRNA.snRNA.304.[98] 26 −0.19 −0.15 3.0 1.2 −0.3 1.11 0.02 262MER54A.ERVL.LTR.626.[458] 59 0.16 0.23 3.0 −0.3 0.5 1.11 0.02 263MLT1I.MaLR.LTR.11191.[218] 507 0.07 0.17 1.5 1.1 1.3 1.11 0.01 264L2.L2.LINE.403973.[230] 24844 0.13 0.15 2.7 0.9 −0.2 1.10 0.02 265LTR43.ERV1.LTR.436.[329] 72 −0.03 0.06 0.6 2.0 1.2 1.10 0.01 266LTR17.ERV1.LTR.830.[578] 343 0.78 0.95 3.1 −0.6 0.2 1.09 0.02 267HERVK11.ERVK.LTR.300.[1278

39 0.61 0.91 2.2 0.7 0.8 1.09 0.02 268 MER89.ERV1.LTR.1339.[310] 1030.20 0.19 2.8 0.7 0.2 1.09 0.02 269 L1PA5.L1.LINE.10904.[1449] 547 0.260.51 2.3 0.5 0.8 1.09 0.01 270 U3.snRNA.snRNA.228.[102] 13 −0.28 −0.383.1 −1.0 1.0 1.09 0.02 271 LTR34.ERV1.LTR.361.[370] 41 0.26 0.25 3.0−0.2 0.1 1.08 0.02 272 LTR27B- 5 0.42 0.76 2.0 0.4 1.0 1.07 0.02 273MER8.MER2_type.DNA.1884.[1

873 0.02 0.08 0.8 0.5 1.6 1.07 0.01 274 LTR26.ERV1.LTR.604.[405] 1210.14 0.16 3.0 0.9 −0.4 1.07 0.02 275 HERVL74.ERVL.LTR.473.[425] 25 0.200.27 2.6 0.5 0.4 1.06 0.01 276 MER91A.Tip100.DNA.3430.[12

216 0.14 0.11 3.2 0.8 −0.4 1.06 0.02 277 LTR36- 5 −0.30 0.04 0.1 1.7 1.21.06 0.02 278 HERV3.ERV1.LTR.256.[1560] 96 0.05 0.10 −0.1 −2.2 2.1 1.050.02 279 MER61D- 8 0.52 0.84 2.4 −0.3 0.9 1.05 0.01 280 tRNA-Lys- 11−0.36 −0.39 2.1 0.8 0.1 1.05 0.02 281 LTR73.ERV1.LTR.205.[393] 17 0.370.56 2.6 −0.1 0.7 1.03 0.01 282 MER72B.ERV1.LTR.177.[394] 11 0.09 0.291.1 1.6 0.7 1.03 0.01 283 L1P2.L1.LINE.2017.[1383] 105 0.27 0.58 2.5−0.1 0.9 1.03 0.01 284 L1PA16.L1.LINE.13098.[813] 663 0.28 0.50 3.5 −0.60.5 1.03 0.02 285 L1M3b.L1.LINE.813.[836] 35 0.36 0.61 3.2 −1.0 0.8 1.020.01 286 L1PBa1.L1.LINE.656.[1545] 48 0.47 0.72 2.1 0.3 0.6 1.02 0.01287 L1P1.L1.LINE.2860.[838] 183 0.27 0.59 2.6 0.0 0.8 1.02 0.01 288Tigger1.MER2_type.DNA.1192

902 0.14 0.29 3.2 0.2 1.1 1.02 0.02 289 MER21C.ERV1.LTR.4871.[411] 3620.05 0.11 1.1 1.0 1.3 1.02 0.01 290 LTR19A- 13 0.11 0.30 0.8 0.5 1.51.01 0.01 291 L1MA5.L1.LINE.4086.[656] 425 0.16 0.33 3.0 −1.0 0.3 1.010.01 292 tRNA-Met.tRNA.tRNA.48.[57] 6 −0.14 −0.36 0.7 1.9 0.9 1.01 0.01293 L1P.L1.LINE.1589.[520] 9723 0.23 0.49 2.9 −1.0 1.0 1.01 0.01 294U13.snRNA.snRNA.178.[98] 35 −0.27 −0.24 3.8 −0.8 0.1 1.00 0.03 295MER44A.MER2_type.DNA.2119.

117 −0.21 −0.11 2.2 1.5 0.2 0.99 0.02 296 MER110A.ERV1.LTR.644.[254] 410.13 0.21 1.9 1.3 0.3 0.99 0.01 297 MER93a.ERV1.LTR.311.[247] 55 −0.19−0.19 3.3 0.7 −0.1 0.98 0.03 298 MER74C.ERVL.LTR.226.[323] 9 0.02 0.360.6 1.1 1.2 0.98 0.00 299 MLT1H.MaLR.LTR.9741.[277] 969 0.07 0.15 1.70.9 1.1 0.98 0.01 300 LTR29.ERV1.LTR.667.[307] 54 0.07 0.18 2.4 0.7 1.20.97 0.03 301 MLT2C2.ERVL.LTR.1282.[249] 63 0.19 0.27 3.0 0.0 0.9 0.970.02 302 MER6A.MER2_type.DNA.805.[4

85 0.07 0.14 1.0 0.4 1.1 0.97 0.01 303 MST-int.MaLR.LTR.563.[425] 130.25 0.43 2.1 0.4 0.7 0.95 0.00 304 LTR14C.ERVK.LTR.138.[512] 30 0.400.57 2.0 0.0 0.8 0.95 0.01 305 MLT1B.MaLR.LTR.17353.[278] 1167 0.07 0.142.0 0.2 1.1 0.95 0.01 306 L1PBb.L1.LINE.271.[1050] 14 0.12 0.32 1.5 0.21.2 0.94 0.03 307 X. Rago 494 −0.26 0.06 1.5 1.0 0.8 0.94 0.01 308AluYh.Alu.SINE.23.[120] 65 0.19 0.26 2.5 0.1 0.2 0.93 0.01 309HERVH48.ERV1.LTR.115.[1792

58 0.62 0.67 2.4 0.7 −0.1 0.93 0.01 310 Tigger5.MER2_type.DNA.2895

365 −0.12 −0.04 1.5 1.8 0.1 0.93 0.01 311 L1PA3.L1.LINE.10281.[1836]1276 0.18 0.53 1.8 0.6 0.7 0.93 0.00 312 MER9B.ERVK.LTR.61.[431] 11 0.250.41 1.8 −0.1 1.2 0.93 0.01 313 Charlie8.MER1_type.DNA.758

569 0.07 0.08 2.2 0.3 0.3 0.93 0.00 314 LTR46- 7 0.44 0.50 0.7 −0.1 1.30.92 0.02 315 L1MC3.L1.LINE.12792.[547] 881 −0.01 0.13 1.4 0.0 1.3 0.920.02 316 MLT1J1.MaLR.LTR.3407.[217] 142 0.07 0.15 2.1 0.1 0.8 0.92 0.01317 HERVK3.ERVK.LTR.341.[1001] 46 0.01 0.15 1.6 0.6 1.0 0.92 0.01 318 K.Sunami 749 −0.29 0.06 1.9 0.6 0.6 0.92 0.00 319 L1M3d.L1.LINE.765.[649]54 0.13 0.34 2.6 −0.4 1.0 0.91 0.01 320 MER34.ERV1.LTR.2364.[259] 4190.04 0.11 2.1 0.9 0.6 0.91 0.01 321 LTR31.ERV1.LTR.249.[407] 19 0.320.32 2.7 0.7 0.4 0.91 0.02 322 MER45C.Tip100.DNA.1080.[29

62 0.14 0.11 2.5 1.1 −0.3 0.91 0.01 323 L1PA8A.L1.LINE.2210.[1386] 1340.27 0.51 3.2 −1.2 0.5 0.90 0.02 324 L1MA6.L1.LINE.4693.[601] 247 0.120.31 1.8 −0.3 0.8 0.90 0.00 325 MER30.MER1_type.DNA.3898.[

304 −0.08 −0.01 1.8 1.6 −0.6 0.90 0.01 326 HERVK14.ERVK.LTR.297.[755] 640.27 0.40 2.1 0.2 0.5 0.90 0.01 327 MER21B.ERV1.LTR.3565.[442] 275 0.010.06 −0.9 1.2 1.2 0.89 0.01 328 L1MA2.L1.LINE.6911.[992] 385 0.22 0.432.0 −0.1 0.9 0.89 0.00 329 LTR49.ERV1.LTR.1406.[325] 164 0.09 0.18 2.3−0.2 0.9 0.89 0.01 330 MER21- 33 0.21 0.18 3.6 −0.9 −0.5 0.89 0.03 331MLT1J2.MaLR.LTR.7867.[215] 354 0.02 0.09 1.1 0.2 1.2 0.89 0.01 332MER46A.MER2_type.DNA.3411.

178 −0.14 −0.05 1.7 1.7 0.3 0.89 0.01 333 X. Woloszynska 486 −0.26 0.061.4 1.6 0.4 0.88 0.01 334 HERVK22.ERVK.LTR.404.[1292

83 0.09 0.23 0.8 0.3 1.2 0.88 0.01 335 L1PB.L1.LINE.1520.[464] 1561 0.260.47 2.1 −0.4 0.4 0.88 0.00 336 U2.snRNA.snRNA.1053.[44] 53 −0.19 −0.121.4 1.4 0.0 0.87 0.01 337 LTR2B.ERV1.LTR.310.[453] 68 0.22 0.41 1.9 1.10.6 0.87 0.01 338 L1MA5A.L1.LINE.3165.[541] 182 0.14 0.30 2.2 −0.3 0.60.87 0.00 339 MER87.ERV1.LTR.405.[280] 31 0.17 0.24 2.2 0.0 0.7 0.860.01 340 AluYb.Alu.SINE.151.[123] 2413 0.15 0.26 2.0 0.7 0.5 0.86 0.00341 body.Tip100 1685 0.04 0.07 1.4 1.1 0.8 0.86 0.00 342LTR60.ERV1.LTR.250.[309] 23 0.25 0.43 1.8 0.2 0.5 0.86 0.00 343MER5A.MER1_type.DNA.35576.

3092 −0.05 −0.01 −0.1 1.7 0.9 0.85 0.01 344 Tigger5a.MER2_type.DNA.254

159 −0.13 −0.05 1.7 1.5 0.2 0.85 0.02 345 MER4- 67 0.12 0.18 2.0 0.1 0.80.85 0.01 346 LTR38B.ERV1.LTR.217.[386] 21 0.14 0.25 2.1 −0.5 0.8 0.850.01 347 L1P5.L1.LINE.1531.[587] 75 −0.10 0.12 0.6 1.6 0.3 0.84 0.01 348L1PA15.L1.LINE.8233.[962] 458 0.23 0.47 1.6 0.2 0.7 0.84 0.00 349MER83C.ERV1.LTR.146.[299] 12 0.43 0.57 3.1 −0.7 0.1 0.84 0.02 350MER57A- 127 −0.06 0.11 0.3 1.6 0.7 0.83 0.01 351MER67C.ERV1.LTR.1468.[341] 103 −0.07 0.06 1.2 1.0 0.8 0.83 0.00 352LTR10E.ERV1.LTR.253.[458] 18 0.23 0.28 1.8 0.3 0.5 0.83 0.01 353MLT2C1.ERVL.LTR.2455.[246] 148 0.06 0.15 3.9 2.9 −0.6 0.83 0.10 354MER65A- 45 −0.27 −0.14 1.3 1.4 0.1 0.82 0.01 355 tRNA-Lys- 6 −0.19 −0.390.0 −0.2 1.2 0.82 0.00 356 L1PA14.L1.LINE.3561.[941] 187 0.32 0.58 2.50.2 0.5 0.82 0.01 357 AluYa5.Alu.SINE.3978.[292] 3098 0.18 0.27 2.5 −0.5−0.1 0.82 0.01 358 LTR16D.ERVL.LTR.1747.[217] 64 0.16 0.26 1.4 0.7 0.50.82 0.01 359 LTR56.ERV1.LTR.939.[275] 83 0.03 0.11 2.3 −0.3 1.2 0.820.02 360 body.L1 53658 0.06 0.19 2.4 −0.3 0.7 0.82 0.01 361L1PB2.L1.LINE.2666.[831] 167 0.33 0.53 2.4 −1.0 0.6 0.82 0.01 362tRNA-Ile- 1 −0.46 0.10 −1.0 2.1 0.1 0.82 0.01 363LTR72.ERV1.LTR.149.[355] 34 0.14 0.19 1.8 0.5 0.5 0.82 0.00 364LOR1b.ERV1.LTR.1086.[334] 88 0.03 0.15 2.0 −0.1 0.6 0.81 0.00 365L1PA4.L1.LINE.11462.[1602] 723 0.32 0.66 1.9 −0.3 0.6 0.81 0.01 366LTR10C- 1 −0.79 −0.54 3.4 0.9 −1.1 0.81 0.03 367 L1P4.L1.LINE.5156.[529]356 0.20 0.43 1.7 −0.4 0.7 0.81 0.00 368 LTR43B.ERV1.LTR.213.[318] 18−0.14 0.01 −0.9 0.9 1.2 0.81 0.01 369 L1M3de.L1.LINE.497.[598] 24 0.240.42 2.0 0.3 0.7 0.80 0.01 370 HERVL66.ERVL.LTR.104.[735] 14 0.09 0.320.8 1.1 0.9 0.80 0.00 371 K. Yang 810 −0.29 0.06 1.1 1.1 0.8 0.80 0.00372 Tigger3(Golem).MER2_type.D

306 −0.04 0.08 0.2 1.7 0.5 0.80 0.02 373 LTR51.ERV1.LTR.399.[424] 34−0.06 0.04 −0.5 1.7 0.7 0.80 0.02 374 L1HS.L1.LINE.1696.[2016] 365 −0.020.32 1.1 1.1 0.9 0.80 0.00 375 REP522.telo.Satellite.217.

96 0.30 0.14 1.9 0.8 0.1 0.80 0.01 376 THE1C- 21 0.48 0.67 2.0 −0.4 0.80.79 0.01 377 MER110- 11 −0.35 −0.17 2.3 0.7 −0.3 0.79 0.02 378body.tRNA 241 −0.02 −0.17 0.0 0.0 1.5 0.79 0.01 379L1MD1.L1.LINE.6126.[612] 507 0.03 0.18 1.6 0.6 0.7 0.79 0.00 380LTR66.ERVL.LTR.515.[216] 44 0.08 0.24 0.6 −0.1 1.3 0.79 0.00 381MLT1F2.MaLR.LTR.4152.[353] 222 0.04 0.12 0.9 1.0 0.8 0.79 0.00 382L1MCa.L1.LINE.7557.[512] 462 0.10 0.28 1.8 0.5 0.5 0.78 0.00 383MER54B.ERVL.LTR.417.[407] 30 0.08 0.18 2.8 −0.7 0.5 0.78 0.01 384MLT1A0- 41 0.05 0.23 1.3 1.0 1.0 0.78 0.01 385 LTR22B.ERVK.LTR.219.[438]19 −0.06 0.13 −0.1 1.6 0.6 0.78 0.07 386 MSTC- 20 0.09 0.26 0.7 0.4 1.00.78 0.00 387 K. Chalitchagorn 729 −0.29 0.06 1.8 0.8 0.6 0.77 0.00 388MER20B.MER1_type.DNA.4150.

301 0.05 0.11 2.2 −0.0 0.6 0.77 0.01 389 HSATI.Satellite.Satellite.

3 −0.42 −0.25 1.2 1.3 0.3 0.77 0.01 390 L1PA2.L1.LINE.4666.[2016] 932−0.01 0.30 1.2 1.4 0.4 0.77 0.00 391 L1ME1.L1.LINE.26938.[488] 2011 0.030.15 1.5 0.8 0.5 0.76 0.00 392 MER48.ERV1.LTR.192.[361] 93 0.37 0.43 0.90.9 0.7 0.76 0.00 393 L1MA4.L1.LINE.8983.[621] 850 0.13 0.33 1.7 −0.00.6 0.75 0.00 394 MLT1C.MaLR.LTR.19102.[313] 1596 0.07 0.12 1.3 1.2 0.60.75 0.00 395 L1MA4A.L1.LINE.5823.[836] 346 0.17 0.40 1.9 −0.4 0.6 0.750.00 396 MER49.ERV1.LTR.1296.[399] 133 0.07 0.14 1.9 −0.0 0.8 0.75 0.01397 MER58C.MER1_type.DNA.2066.

143 −0.12 −0.07 1.4 1.1 −0.0 0.75 0.02 398 LTR23.ERV1.LTR.840.[205] 87−0.10 −0.09 2.0 0.7 −0.0 0.75 0.02 399 L1PB3.L1.LINE.3302.[827] 182 0.230.44 2.0 0.2 0.4 0.75 0.00 400 AluSc.Alu.SINE.48789.[278] 13426 0.030.12 2.0 0.1 0.4 0.75 0.00 401 MER52A- 4 0.33 0.62 1.6 −0.5 0.6 0.740.00 402 LTR57- 14 −0.07 0.10 1.0 0.9 0.9 0.74 0.01 403LTR55.ERV.LTR.402.[366] 26 −0.12 0.06 −0.9 1.3 1.1 0.74 0.02 404LTR2C.ERV1.LTR.237.[343] 91 0.03 0.06 0.1 1.1 1.0 0.74 0.01 405L1ME4a.L1.LINE.38237.[216] 2335 −0.08 −0.02 1.0 1.4 −0.1 0.74 0.01 406MER61C.ERV1.LTR.284.[360] 23 0.05 0.28 1.5 1.7 0.5 0.73 0.01 407AluYb9.Alu.SINE.3147.[299] 2364 0.16 0.27 2.0 −0.2 0.5 0.73 0.00 408AluYg6.Alu.SINE.677.[254] 411 0.10 0.24 1.6 0.5 0.6 0.72 0.00 409tRNA-Leu- 2 0.17 −0.23 −0.4 −0.2 1.4 0.71 0.01 410LTR5_Hs.ERVK.LTR.601.[880] 134 0.24 0.34 1.7 −0.8 1.0 0.71 0.01 411MER88.ERVL.LTR.110.[327] 11 0.49 0.44 3.8 −0.9 −0.5 0.71 0.03 412AluSg/x.Alu.SINE.25834.[16

3246 0.03 0.07 1.6 0.4 0.1 0.70 0.00 413 MER5A1.MER1_type.DNA.14831

917 −0.06 −0.02 −0.6 1.4 1.0 0.70 0.01 414 ERVL-E.ERVL.LTR.9525.[461]451 0.01 0.11 0.8 0.6 0.8 0.70 0.01 415 HAL1.L1.LINE.27468.[342] 22240.09 0.16 1.6 0.2 0.1 0.70 0.00 416 MLT1G1- 15 0.12 0.20 1.7 0.4 0.60.70 0.01 417 Kanga2_a.Tc2.DNA.1465.[277

109 0.06 0.15 1.3 0.5 0.5 0.69 0.00 418 L1M3.L1.LINE.7700.[374] 715 0.070.22 1.9 −0.4 0.6 0.69 0.00 419 L1MB5.L1.LINE.8813.[405] 822 0.09 0.102.2 −0.2 −0.1 0.69 0.01 420 AluYg.Alu.SINE.111.[105] 441 0.09 0.22 1.70.6 0.1 0.69 0.00 421 LTR16C.ERVL.LTR.9063.[251] 462 0.11 0.18 1.6 −0.20.6 0.69 0.00 422 D20S16.Satellite.Satellite

18 1.05 0.93 2.0 0.8 −0.1 0.69 0.01 423 L1M4b.L1.LINE.7423.[511] 454−0.00 0.16 1.5 0.5 0.6 0.69 0.00 424 MER102a.MER1_type.DNA.309.

22 0.17 0.23 1.3 0.6 0.3 0.68 0.00 425 Tigger2.MER2_type.DNA.5206

578 0.11 0.21 1.9 0.3 −0.4 0.68 0.00 426 Charlie11.MER1_type.DNA.87

5 0.28 0.37 1.6 −0.0 0.3 0.68 0.00 427 AluSg1.Alu.SINE.6311.[280] 13000.02 0.09 1.8 0.4 −0.1 0.68 0.00 428 MER66A.ERV1.LTR.346.[353] 44 −0.040.04 0.0 −0.1 1.1 0.68 0.00 429 MER21A.ERV1.LTR.1793.[398] 160 0.05 0.081.0 0.9 0.2 0.68 0.00 430 LTR26E.ERV1.LTR.307.[375] 43 0.20 0.14 1.7 0.20.1 0.68 0.01 431 MARNA.Mariner.DNA.3249.[18

181 −0.10 −0.02 0.0 1.3 0.1 0.67 0.01 432 L1MCb.L1.LINE.2863.[624] 1540.04 0.25 1.7 −0.5 0.6 0.67 0.00 433 LTR39.ERV1.LTR.1193.[393] 135 0.080.16 2.2 0.6 0.2 0.67 0.01 434 MER61D.ERV1.LTR.263.[361] 21 0.25 0.441.4 −0.5 0.8 0.67 0.01 435 MER58A.MER1_type.DNA.12543

665 −0.05 0.03 1.2 1.2 0.5 0.67 0.00 436 MER101- 39 0.16 0.25 1.3 0.60.5 0.67 0.02 437 LTR27B.ERV1.LTR.540.[461] 59 0.08 0.20 1.5 0.3 0.40.67 0.01 438 AluYa.Alu.SINE.46.[110] 3156 0.17 0.27 2.0 0.0 −0.0 0.660.01 439 HERVH.ERV1.LTR.5774.[958] 836 0.95 1.25 2.0 −0.4 0.3 0.66 0.01440 Charlie4.MER1_type.DNA.136

303 0.03 0.06 1.9 −0.2 0.2 0.66 0.00 441 L1MC2.L1.LINE.5920.[505] 4750.02 0.14 2.0 0.7 0.4 0.65 0.01 442 MER67B- 1 0.68 −0.72 −0.4 −0.7 1.30.65 0.01 443 AluY.Alu.SINE.135761.[288] 82937 0.07 0.18 1.5 0.0 0.40.65 0.00 444 MER4A1- 66 0.09 0.25 1.5 0.9 0.0 0.65 0.00 445MLT1K.MaLR.LTR.18519.[227] 1025 0.02 0.05 0.0 0.5 0.9 0.65 0.00 446Arthur1.Tip100.DNA.4836.[2

269 −0.01 0.07 0.7 0.6 0.9 0.64 0.01 447 MER52A.ERV1.LTR.1824.[1041

206 0.07 0.13 1.0 0.5 0.6 0.64 0.00 448 BLACKJACK.AcHobo.DNA.2099.

104 0.04 0.16 1.5 0.4 0.4 0.64 0.00 449 MER4A1_.ERV1.LTR.380.[486] 1030.07 0.22 1.6 0.1 0.5 0.64 0.01 450 LTR45C.ERV1.LTR.393.[324] 34 0.290.35 2.7 −1.0 −0.2 0.64 0.01 451 LTR53.ERVL.LTR.666.[362] 41 0.12 0.211.3 0.1 0.5 0.63 0.00 452 LTR12D.ERV1.LTR.502.[810] 308 0.30 0.40 1.71.0 0.0 0.63 0.01 453 MER31A- 11 0.17 0.33 1.9 −0.4 −0.1 0.63 0.01 454MER44C.MER2_type.DNA.802.[

57 −0.02 0.07 0.5 1.4 0.3 0.63 0.00 455 LTR48B- 3 −0.52 −0.35 2.3 0.3−0.2 0.62 0.02 456 L1MC.L1.LINE.16426.[272] 9792 −0.00 0.09 1.2 0.6 0.70.62 0.00 457 Ricksha.MuDR.DNA.1551.[287

86 0.03 0.12 2.1 0.1 −0.0 0.62 0.00 458 MER57B.ERV1.LTR.1225.[343] 940.04 0.24 1.0 1.1 0.3 0.62 0.00 459 MER57B- 35 0.03 0.27 1.3 0.7 0.40.62 0.00 460 MLT1H2.MaLR.LTR.4227.[216] 208 0.11 0.15 1.6 −0.4 −0.00.61 0.00 461 LTR38- 5 −0.19 −0.26 0.4 −0.0 0.9 0.61 0.00 462MER61B.ERV1.LTR.409.[332] 43 0.16 0.24 1.7 −0.2 −0.1 0.61 0.00 463L1PA15- 64 −0.06 0.21 0.5 0.7 0.6 0.61 0.00 464 MER50- 36 0.10 0.20 0.00.6 0.8 0.61 0.01 465 LSAU.Satellite.Satellite.4

10 0.34 −0.08 −0.7 1.8 0.4 0.60 0.01 466 Charlie10.MER1_type.DNA.22

133 −0.03 0.06 0.5 0.6 0.8 0.60 0.01 467 L1P4d.L1.LINE.204.[1102] 170.21 0.39 1.1 0.5 0.3 0.60 0.00 468 LTR12.ERV1.LTR.964.[633] 3627 0.330.40 1.3 0.7 0.5 0.60 0.00 469 L1P3.L1.LINE.4518.[756] 219 0.17 0.39 1.6−0.3 −0.1 0.60 0.00 470 L1MEa.L1.LINE.1665.[407] 115 0.03 0.16 1.0 0.80.7 0.60 0.00 471 MER46B.MER2_type.DNA.2000.

134 −0.13 −0.05 0.2 1.1 0.4 0.59 0.01 472 MER7A.MER2_type.DNA.5173.[

322 −0.08 −0.00 −0.1 1.3 −0.2 0.59 0.01 473 tRNA-Val- 7 0.29 0.16 1.00.7 0.1 0.59 0.01 474 MER4A- 10 0.18 0.18 1.3 0.1 0.2 0.59 0.00 475L1PB1.L1.LINE.11421.[1064] 653 0.28 0.51 1.6 0.4 −0.2 0.58 0.00 476Charlie4a.MER1_type.DNA.23

212 0.04 0.07 2.0 −0.5 0.3 0.58 0.00 477 Tigger6.MER2_type.DNA.253.

77 0.10 0.18 1.1 0.0 0.5 0.58 0.00 478 LTR71A.ERV1.LTR.164.[385] 24 0.250.41 1.8 0.1 0.4 0.58 0.01 479 MER89- 25 0.16 0.21 1.9 −0.7 0.2 0.570.01 480 MLT1E1.MaLR.LTR.2001.[322] 176 0.03 0.14 1.0 0.7 0.3 0.57 0.00481 MER58.MER1_type.DNA.2330.[

1464 −0.08 −0.02 −0.8 1.5 0.3 0.57 0.01 482 L1MB2.L1.LINE.7699.[402] 5960.04 0.13 1.2 0.4 0.3 0.57 0.00 483 MER75B.PiggyBac.DNA.111.[1

4 0.17 0.31 1.4 −0.7 0.9 0.56 0.01 484 L1ME3A.L1.LINE.16330.[362] 11270.00 0.09 1.0 0.7 0.4 0.56 0.00 485 MER119.MER1_type.DNA.1169.

93 −0.14 −0.06 −0.2 1.0 0.5 0.56 0.01 486 MER106A.MER1_type.DNA.689.

45 0.04 0.06 0.4 0.9 0.8 0.56 0.00 487 HERVL40.ERVL.LTR.1217.[378

49 −0.01 0.12 0.2 1.8 0.3 0.56 0.02 488 L1M2.L1.LINE.9352.[648] 523 0.130.32 1.2 −0.0 0.3 0.56 0.00 489 MER41- 29 −0.06 0.14 −0.4 1.0 0.0 0.560.00 490 body.Mariner 855 −0.05 0.08 −0.7 1.5 0.4 0.56 0.01 491Zaphod.Tip100.DNA.2063.[32

166 0.00 0.10 1.6 0.4 0.3 0.55 0.00 492 MER34B.ERV1.LTR.1289.[331] 116−0.08 0.03 −0.3 1.4 0.4 0.54 0.01 493 tRNA-Glu- 13 −0.27 −0.34 1.3 −0.20.5 0.54 0.00 494 LTR12C.ERV1.LTR.2616.[1340

2692 0.31 0.36 1.4 0.5 −0.3 0.54 0.01 495 AluJ/FRAM.Alu.SINE.1750.[7

116 0.01 0.09 0.6 0.3 0.9 0.54 0.00 496 L1M3a.L1.LINE.683.[590] 21 0.070.20 1.5 0.0 0.3 0.54 0.00 497 HERVL-C1.ERVL.LTR.7.[980] 1 0.09 0.79 0.60.9 0.5 0.54 0.01 498 L1M.L1.LINE.11466.[335] 43253 0.02 0.13 1.5 0.40.1 0.54 0.00 499 MER72.ERV1.LTR.736.[435] 65 0.08 0.20 1.0 0.5 0.4 0.540.00 500 L1M1.L1.LINE.10118.[932] 594 0.10 0.33 0.9 0.6 0.5 0.54 0.00501 L1MD.L1.LINE.10847.[339] 3480 −0.01 0.11 0.8 0.6 0.6 0.54 0.00 502body.SINE 197952 0.02 0.09 1.1 0.3 0.3 0.53 0.00 503 body.Tc2 428 −0.010.05 0.6 0.4 0.5 0.53 0.00 504 L1MB8.L1.LINE.15156.[428] 1204 0.04 0.121.5 −0.2 0.2 0.53 0.00 505 LTR16B.ERVL.LTR.3456.[292] 190 0.15 0.26 2.0−0.3 0.1 0.53 0.00 506 MIR.MIR.SINE.203898.[147] 35264 −0.03 −0.03 0.01.4 0.5 0.52 0.01 507 L1MEc.L1.LINE.21328.[480] 1317 −0.03 0.12 1.3 −0.10.5 0.52 0.00 508 MER90a.ERV1.LTR.1165.[326] 91 0.17 0.17 1.8 0.3 −0.50.52 0.01 509 L1P4c.L1.LINE.93.[937] 7 0.28 0.47 1.3 −0.6 0.7 0.52 0.00510 LTR12_.ERV1.LTR.664.[497] 3364 0.32 0.39 0.9 −0.3 0.5 0.51 0.00 511un.genebody 54202 −0.06 −0.12 0.5 −0.1 0.7 0.51 0.00 512L1MA3.L1.LINE.8131.[987] 542 0.17 0.39 1.5 −0.4 0.4 0.51 0.00 513MER34D- 1 −0.56 −0.44 2.0 0.1 −0.3 0.51 0.01 514L1MC4.L1.LINE.29881.[332] 4239 −0.02 0.05 0.9 0.5 0.3 0.50 0.00 515body.acro 12 0.37 0.80 1.2 0.4 0.5 0.50 0.00 516L1MCc.L1.LINE.6889.[452] 307 −0.03 0.15 1.1 0.9 −0.2 0.50 0.00 517L1M3e.L1.LINE.981.[813] 34 0.15 0.33 1.3 −0.3 0.1 0.50 0.00 518MER81.AcHobo.DNA.3623.[94] 196 0.05 0.08 0.7 0.0 0.6 0.50 0.00 519LTR37A.ERV1.LTR.1957.[224] 109 0.01 0.13 1.1 1.0 −0.1 0.50 0.00 520MER34C_- 1 0.20 −0.09 −0.1 1.3 0.3 0.50 0.04 521L1P4a.L1.LINE.731.[1306] 55 0.28 0.55 1.5 0.2 −0.1 0.49 0.00 522 MER31-65 −0.12 0.02 0.4 0.8 −0.1 0.49 0.00 523 7SK.RNA.RNA.715.[165] 58 0.210.32 1.1 −0.5 0.4 0.49 0.00 524 LTR40b.ERVL.LTR.1229.[270] 62 0.05 0.150.5 0.5 0.5 0.49 0.00 525 SATR2.Satellite.Satellite.

60 −0.19 −0.12 2.3 −0.1 −0.6 0.49 0.02 526 L1MD3.L1.LINE.7482.[311] 573−0.06 0.02 −0.5 1.0 0.6 0.49 0.00 527 Tigger8.MER2_type.DNA.837.

50 0.09 0.12 1.7 −0.3 0.2 0.48 0.00 528 LTR15.ERV1.LTR.311.[376] 25 0.040.18 1.0 −0.1 0.6 0.48 0.00 529 AluYh9.Alu.SINE.183.[159] 56 0.13 0.211.2 0.7 0.0 0.48 0.00 530 MIRb.MIR.SINE.278083.[144] 17373 −0.03 −0.03−0.3 1.5 0.1 0.48 0.01 531 L1M4.L1.LINE.19504.[380] 2246 0.00 0.13 1.10.0 0.2 0.48 0.00 532 LTR24.ERV1.LTR.308.[302] 101 −0.09 −0.03 0.5 0.80.3 0.47 0.00 533 L1MEb.L1.LINE.5722.[435] 329 −0.05 0.09 0.9 0.5 0.30.47 0.00 534 MER41D.ERV1.LTR.435.[299] 62 −0.15 −0.10 −0.1 −0.3 0.80.47 0.00 535 L1M5.L1.LINE.63689.[284] 4051 −0.02 0.07 1.0 0.4 0.4 0.470.00 536 MER45A.Tip100.DNA.3214.[14

243 0.09 0.08 0.9 0.4 0.2 0.47 0.00 537 Alu.Alu.SINE.6244.[52] 1815210.03 0.10 1.1 0.6 −0.1 0.47 0.00 538 MER3.MER1_type.DNA.10996.[

2609 −0.05 0.01 0.5 0.8 0.5 0.47 0.00 539 ACRO1.acro.Satellite.40.[7

12 0.37 0.80 1.0 1.0 0.1 0.46 0.00 540 ERVL-C1.ERVL.LTR.334.[700] 18−0.16 0.09 −0.4 1.4 0.4 0.46 0.01 541 LTR54.ERV1.LTR.1087.[261] 128−0.07 0.02 −0.1 0.4 0.6 0.46 0.01 542 AluYd.Alu.SINE.65.[107] 576 0.060.15 0.9 0.4 0.5 0.46 0.00 543 HERVS71.ERV1.LTR.149.[1952

83 −0.44 −0.45 1.7 −1.0 0.7 0.45 0.01 544 MER101.ERV1.LTR.379.[292] 840.04 0.12 0.8 0.1 0.4 0.45 0.00 545 LTR40c.ERVL.LTR.609.[321] 24 −0.14−0.01 −0.3 1.2 0.3 0.45 0.00 546 HY4.scRNA.scRNA.157.[79] 10 0.03 0.01−0.7 0.9 0.4 0.45 0.01 547 HSMAR2.Mariner.DNA.1721.[6

108 −0.10 0.05 −0.5 0.8 0.7 0.45 0.00 548 Charliela.MER1_type.DNA.36

337 −0.16 −0.07 1.0 0.6 −0.2 0.44 0.01 549 MER75.PiggyBac.DNA.551.[33

44 0.07 0.15 1.7 0.1 0.2 0.44 0.01 550 AluYd8.Alu.SINE.853.[274] 5620.06 0.14 1.4 0.0 0.3 0.44 0.00 551 L1MD2.L1.LINE.12388.[485] 944 0.030.13 1.0 0.5 −0.4 0.44 0.00 552 MER76- 9 0.03 0.20 0.5 0.0 0.5 0.44 0.00553 L1M2a.L1.LINE.515.[883] 26 −0.09 0.19 0.6 0.8 0.4 0.44 0.00 554L1MA10.L1.LINE.5419.[291] 275 −0.00 0.12 1.3 0.3 0.1 0.43 0.00 555Tigger6a.MER2_type.DNA.681

54 0.09 0.18 1.3 −0.5 0.1 0.43 0.00 556 Tigger7.MER2_type.DNA.4405

196 −0.05 0.05 0.7 0.6 0.2 0.43 0.00 557 tRNA-Thr- 4 −0.41 −0.23 0.7 0.50.3 0.43 0.01 558 L1ME2.L1.LINE.15797.[423] 1122 0.01 0.11 1.1 0.0 −0.30.43 0.00 559 L1PBa.L1.LINE.1915.[1205] 171 0.29 0.57 1.2 −0.3 0.3 0.430.00 560 Charlie1.MER1_type.DNA.491

1048 −0.12 −0.04 0.8 0.8 −0.2 0.43 0.01 561 L1M4c.L1.LINE.7787.[595] 4560.02 0.19 0.7 0.3 0.3 0.43 0.00 562 MER107.MER1_type.DNA.320.[

13 −0.10 −0.24 −0.0 0.0 0.8 0.42 0.00 563 FAM.Alu.SINE.4424.[149] 3550.01 0.06 1.3 0.4 0.0 0.42 0.00 564 MLT1E1A.MaLR.LTR.1054.[326

63 −0.03 0.08 −0.1 1.0 0.0 0.42 0.00 565 LTR1B- 2 0.20 0.20 0.6 −0.7 0.80.42 0.00 566 L1M3c.L1.LINE.1069.[583] 43 −0.07 0.13 0.5 0.7 0.3 0.420.00 567 MER65C.ERV1.LTR.683.[311] 67 −0.04 0.03 −0.4 1.0 0.1 0.42 0.00568 MER34- 28 −0.04 0.09 0.5 0.5 0.4 0.41 0.00 569LTR3B.ERVK.LTR.90.[391] 38 0.11 0.18 0.8 0.7 0.1 0.41 0.00 570tRNA-SeC(e)- 1 −0.24 −0.31 0.5 0.2 0.6 0.41 0.01 571L1M2c.L1.LINE.585.[856] 23 0.26 0.45 1.5 0.0 0.1 0.40 0.00 572MER6B.MER2_type.DNA.656.[1

26 −0.11 −0.03 1.1 −0.2 0.5 0.40 0.01 573 L1MC4a.L1.LINE.28404.[336]2100 −0.02 0.05 0.4 0.4 0.4 0.40 0.00 574 AluJ.Alu.SINE.2554.[134] 21348−0.00 0.02 1.0 0.0 0.0 0.40 0.00 575 MER65C- 9 0.24 0.43 0.7 0.5 0.20.40 0.00 576 MER53.DNA.DNA.5686.[128] 332 −0.05 −0.05 2.2 −0.8 0.2 0.390.02 577 LTR10G.ERV1.LTR.116.[432] 18 0.30 0.43 1.6 −0.4 −0.1 0.39 0.00578 AluYa8.Alu.SINE.107.[226] 52 0.03 0.11 0.8 0.0 0.3 0.39 0.00 579body.CR1 2938 −0.03 0.02 −0.2 0.7 0.2 0.39 0.00 580 tRNA-Phe- 7 0.300.38 1.7 −0.6 0.0 0.38 0.00 581 GSAT.centr.Satellite.65.[3

144 −0.20 −0.25 2.0 −0.5 0.1 0.38 0.01 582 L1MEd.L1.LINE.15988.[333] 903−0.04 0.08 0.8 0.5 0.3 0.38 0.00 583 MER1B.MER1_type.DNA.5233.[

632 0.06 0.09 1.0 0.3 0.0 0.38 0.01 584 L1MEe.L1.LINE.12492.[333] 750−0.01 0.12 0.9 0.5 0.1 0.38 0.00 585 L1ME3.L1.LINE.7572.[348] 3426 0.000.09 0.9 0.4 0.1 0.37 0.00 586 body.MER2_type 5338 −0.01 0.09 0.1 0.30.0 0.37 0.00 587 MER44B.MER2_type.DNA.1256.

106 −0.02 0.09 0.6 0.4 0.3 0.37 0.00 588 AluJb.Alu.SINE.125688.[259

10131 −0.00 0.03 0.9 0.0 0.4 0.37 0.00 589 L1MC5.L1.LINE.20412.[260]1523 −0.03 0.03 0.5 −0.1 0.4 0.37 0.00 590 L1MB4.L1.LINE.8956.[415] 710−0.01 0.08 0.7 0.1 0.4 0.36 0.00 591 MER46C.MER2_type.DNA.2705.

186 −0.08 −0.04 0.7 0.5 −0.4 0.36 0.00 592 body.PiggyBac 121 −0.04 0.06−0.5 0.3 0.6 0.36 0.00 593 ERVL- 17 0.19 0.29 2.0 −0.6 0.2 0.36 0.01 594CER.Satellite.Satellite.35

4 0.94 1.23 1.4 0.1 −0.0 0.36 0.01 595 LTR59.ERV1.LTR.121.[337] 11 0.050.16 1.0 0.5 0.2 0.35 0.00 596 Merlin1_HS.Merlin.DNA.53.[

1 −0.38 −0.64 0.5 0.2 0.5 0.35 0.00 597 L1ME3B.L1.LINE.27528.[351] 17640.01 0.11 0.6 0.0 0.3 0.35 0.00 598 MER105.DNA.DNA.712.[145] 37 −0.15−0.02 −0.1 0.6 0.3 0.35 0.00 599 MER90.ERV1.LTR.678.[317] 148 0.16 0.161.5 −1.1 0.2 0.35 0.01 600 MER61- 11 0.04 0.28 0.7 0.0 0.5 0.34 0.00 601HY3.scRNA.scRNA.509.[87] 51 −0.01 0.04 0.5 0.5 0.3 0.34 0.00 602MER4D0.ERV1.LTR.463.[369] 32 0.17 0.23 1.5 −0.1 −0.3 0.34 0.00 603MLT1D- 38 0.07 0.17 1.3 −0.2 −0.1 0.34 0.00 604MER41G.ERV1.LTR.105.[415] 17 0.20 0.31 1.6 −0.4 −0.2 0.34 0.00 605body.telo 134 0.21 0.11 0.8 −0.2 0.3 0.33 0.00 606MER65B.ERV1.LTR.238.[194] 22 −0.09 −0.00 −1.0 0.5 0.6 0.33 0.00 607LTR44.ERV1.LTR.201.[309] 23 0.14 0.18 0.7 0.0 0.2 0.33 0.00 608tRNA-Ala- 10 −0.13 −0.32 −0.4 0.7 0.4 0.33 0.00 609 tRNA-Asn- 7 −0.10−0.46 1.0 0.2 0.1 0.33 0.00 610 MER65D.ERV1.LTR.415.[277] 42 −0.13 −0.030.1 0.6 0.3 0.33 0.01 611 MER41A- 46 0.01 0.17 0.7 0.6 0.3 0.33 0.00 612U5.snRNA.snRNA.205.[55] 7 −0.26 −0.18 0.5 −0.1 0.2 0.33 0.01 613tRNA-Val- 10 −0.25 −0.41 0.9 −0.0 0.5 0.32 0.00 614MER33.MER1_type.DNA.8040.[

581 −0.05 −0.02 0.5 0.7 −0.3 0.32 0.00 615 MER66B- 9 0.11 0.17 1.2 −0.40.1 0.32 0.00 616 LTR76- 4 −0.10 0.40 −0.7 0.5 0.6 0.32 0.01 617LTR37B.ERV1.LTR.1958.[226] 99 −0.09 0.01 0.1 0.5 0.2 0.32 0.00 618ORSL.Tip100.DNA.1181.[165] 101 0.04 0.07 1.1 −0.4 0.3 0.32 0.00 619L1MDa.L1.LINE.9760.[522] 651 −0.03 0.12 1.2 −0.0 −0.2 0.32 0.00 620L1P4e.L1.LINE.221.[996] 8 0.62 0.94 0.8 0.6 −0.0 0.32 0.00 621MER66B.ERV1.LTR.1407.[302] 138 0.09 0.12 0.8 0.2 0.4 0.31 0.00 622PRIMAX- 10 −0.12 −0.05 −0.4 0.9 −0.1 0.31 0.00 623LTR45B.ERV1.LTR.417.[324] 34 −0.17 −0.12 0.9 0.3 −0.1 0.30 0.01 624MER6C.MER2_type.DNA.136.[1

3 −0.30 −0.13 −0.5 0.7 0.4 0.30 0.00 625 LOR1b- 23 −0.01 0.10 0.4 0.30.3 0.30 0.00 626 tRNA-Ser- 6 −0.32 −0.63 0.9 −0.3 0.6 0.30 0.00 627MER51- 5 −0.23 −0.00 0.9 0.4 0.1 0.29 0.00 628 MER4A1_- 6 0.16 0.37 1.40.7 −0.5 0.29 0.00 629 AluSg.Alu.SINE.80825.[289] 24024 −0.00 0.06 1.00.0 −0.2 0.29 0.00 630 Kanga1.Tc2.DNA.3485.[171] 219 −0.06 0.00 0.4 0.40.0 0.29 0.00 631 AluYc5.Alu.SINE.496.[51] 56 0.07 0.11 1.3 −0.7 0.00.28 0.00 632 AluS.Alu.SINE.2733.[76] 102736 −0.00 0.05 0.3 0.0 0.4 0.280.00 633 Ricksha_c.MuDR.DNA.121.[85

8 −0.15 −0.00 −0.7 1.3 0.1 0.28 0.01 634 LTR64.ERV1.LTR.352.[292] 53−0.04 0.02 0.1 0.2 0.6 0.28 0.01 635 MER21B- 12 −0.14 0.02 0.4 0.5 0.10.27 0.00 636 LTR57.ERVL.LTR.234.[327] 29 0.01 0.12 1.0 −0.2 0.2 0.270.00 637 MER93B.ERV1.LTR.989.[269] 89 −0.05 −0.00 −0.3 0.7 0.0 0.27 0.00638 HSAT4.centr.Satellite.96.[

7 0.36 0.65 1.2 −0.4 0.1 0.27 0.01 639 MER72- 5 −0.33 −0.10 −0.1 0.9−0.2 0.26 0.01 640 MER103.DNA.DNA.6812.[111] 292 −0.01 0.06 −0.4 −0.30.5 0.26 0.00 641 LTR56- 8 0.01 0.28 0.9 −0.4 0.2 0.26 0.00 642Tigger4(Zombi).MER2_type.D

103 −0.05 0.10 0.9 −0.5 0.2 0.26 0.00 643 AluYc.Alu.SINE.50.[73] 2410.05 0.08 1.6 −0.7 −0.1 0.26 0.00 644 MER61F- 5 −0.01 0.23 0.7 0.6 −0.00.25 0.00 645 MER52C.ERV1.LTR.366.[827] 36 0.10 0.09 1.9 0.1 −0.4 0.250.01 646 MER2.MER2_type.DNA.8174.[2

7533 0.00 0.08 1.1 −0.4 −0.1 0.25 0.00 647 tRNA-Arg- 3 −0.43 −0.53 0.70.5 −0.2 0.25 0.00 648 MER82.MER2_type.DNA.3129.[

255 −0.12 −0.03 −0.7 0.7 0.1 0.25 0.00 649 MER70A- 4 −0.18 0.08 0.6 1.1−0.2 0.25 0.00 650 PRIMA4_LTR- 8 0.29 0.42 1.1 −0.2 0.5 0.25 0.00 651AluJo.Alu.SINE.138391.[257

11068 −0.00 0.02 0.5 0.2 0.2 0.25 0.00 652 tRNA-Pro- 3 −0.05 −0.24 0.10.6 0.2 0.24 0.00 653 MER65- 30 −0.06 0.05 −0.1 0.5 0.2 0.24 0.00 654LTR30.ERV1.LTR.170.[560] 43 0.34 0.58 0.7 −0.2 0.1 0.24 0.00 655 MER57-15 −0.07 0.07 0.0 −0.0 0.5 0.24 0.00 656 MLT1- 15 −0.03 0.10 0.6 −0.40.4 0.24 0.00 657 MLT1L.MaLR.LTR.11354.[209] 527 −0.00 0.06 0.0 0.4 0.30.24 0.00 658 MER51E- 1 −0.82 −0.42 1.0 0.3 −0.5 0.24 0.01 659LTR47A.ERVL.LTR.873.[260] 59 −0.09 0.03 −0.4 −0.1 0.5 0.24 0.01 660LTR24C- 1 −0.24 −0.12 −0.7 0.5 0.3 0.24 0.00 661AluYa5/8.Alu.SINE.112.[108

33 0.21 0.31 1.6 −0.7 0.3 0.23 0.00 662 MER91B.Tip100.DNA.1429.[10

66 −0.17 −0.17 2.3 −1.1 −0.0 0.23 0.01 663 LTR50.ERVL.LTR.2809.[267] 1430.03 0.10 −0.5 −0.8 0.6 0.23 0.00 664 HERV30.ERV1.LTR.61.[1647] 13 0.230.39 1.0 −0.6 0.1 0.23 0.00 665 Charlie6.MER1_type.DNA.250

22 −0.12 0.05 −0.4 0.5 0.4 0.23 0.00 666 Charlie9.MER1_type.DNA.158

80 −0.06 0.01 0.5 −0.4 0.4 0.23 0.00 667 MSTB1- 7 0.18 0.19 −0.1 1.1−0.1 0.23 0.01 668 U4.snRNA.snRNA.161.[92] 10 −0.06 −0.05 −0.4 0.5 0.50.23 0.00 669 MER45R.Tip100.DNA.260.[525

31 0.15 0.18 1.4 −0.7 −0.2 0.21 0.00 670 HERV35I.ERV1.LTR.426.[594] 350.10 0.16 1.2 −0.6 0.1 0.21 0.00 671 AluSp.Alu.SINE.50469.[287] 136940.01 0.07 0.7 0.0 −0.0 0.21 0.00 672 L1M2a1.L1.LINE.142.[918] 8 −0.030.34 1.1 −0.4 0.1 0.21 0.00 673 LTR70.ERV1.LTR.128.[673] 14 0.32 0.352.3 0.5 −1.0 0.21 0.01 674 Charlie7.MER1_type.DNA.472

290 −0.04 0.05 0.0 0.0 0.3 0.21 0.00 675 MER113.MER1_type.DNA.4474.

363 −0.07 −0.05 0.8 −0.0 0.5 0.21 0.01 676 body.MER1_type 14452 −0.040.00 −0.1 0.7 −0.3 0.21 0.00 677 Charlie2.MER1_type.DNA.330

382 0.02 0.08 1.3 0.0 −0.4 0.20 0.00 678 MER83B- 10 −0.05 0.02 −0.4 0.70.0 0.20 0.00 679 AluSx.Alu.SINE.332026.[290

45649 −0.01 0.03 0.9 −0.2 0.2 0.19 0.00 680 MER61C- 8 −0.14 0.08 −0.60.9 −0.0 0.19 0.01 681 MER20.MER1_type.DNA.16178.

1409 0.04 0.05 1.0 −0.4 0.2 0.19 0.00 682 Charlie2b.MER1_type.DNA.50

29 −0.08 −0.02 0.4 0.2 0.0 0.19 0.00 683 HAL1b.L1.LINE.7227.[255] 370−0.02 0.08 0.1 0.1 0.4 0.18 0.00 684 MER68.ERVL.LTR.1892.[361] 176 0.070.16 1.0 0.6 0.0 0.18 0.00 685 Tigger3b.MER2_type.DNA.499

444 −0.04 0.10 0.3 0.4 0.0 0.18 0.00 686 MER5C.MER1_type.DNA.1512.[

102 −0.09 −0.03 0.4 0.7 −0.4 0.18 0.00 687 MER83B.ERV1.LTR.147.[252] 21−0.12 0.00 −0.8 0.7 0.4 0.17 0.01 688 LTR19C.ERV1.LTR.213.[410] 26 0.060.09 1.2 −0.5 0.0 0.17 0.00 689 tRNA-Thr- 3 0.27 0.13 −0.9 −0.1 0.5 0.170.01 690 tRNA-Ser- 7 0.13 −0.04 0.0 0.6 0.1 0.17 0.00 691LTR24C.ERV1.LTR.380.[322] 31 −0.04 0.08 0.2 0.5 0.2 0.17 0.00 692body.MuDR 86 0.03 0.12 1.6 −0.0 −0.4 0.16 0.01 693LTR10C.ERV1.LTR.507.[462] 51 0.12 0.09 0.7 0.7 −0.4 0.16 0.01 694 LTR49-80 0.03 0.09 0.3 0.2 0.0 0.16 0.00 695 tRNA-Ser- 1 0.60 0.39 0.6 −0.50.2 0.15 0.00 696 MER21C- 15 0.05 0.16 −0.4 −0.1 0.6 0.15 0.00 697MER121.Unknown.Unknown.919

54 −0.01 −0.01 −0.6 0.8 0.1 0.14 0.00 698 FRAM/FAM.Alu.SINE.530.[68] 480.07 0.06 −0.2 −0.3 0.6 0.14 0.00 699 MER96B.MER1_type?.DNA.2121

215 −0.01 0.01 0.0 −0.1 0.2 0.14 0.00 700 LTR2-int.ERV1.LTR.5.[222] 1−0.43 −0.29 0.6 0.8 −0.3 0.14 0.02 701 body.Merlin 1 −0.38 −0.64 0.0−0.2 0.4 0.14 0.00 702 tRNA-Glu- 17 −0.21 −0.29 1.5 −1.0 0.2 0.13 0.01703 MER31B.ERV1.LTR.1459.[309] 111 0.02 0.05 0.7 0.3 −0.4 0.13 0.00 704Charlie2a.MER1_type.DNA.16

113 0.04 0.11 −0.4 0.5 0.3 0.13 0.00 705 MER63B.AcHobo.DNA.544.[368

28 0.13 0.14 0.8 −1.9 0.6 0.13 0.03 706 MER117.MER1_type.DNA.4409.

192 −0.01 0.02 −0.3 0.6 0.2 0.13 0.00 707 body.MER1_type? 406 0.02 0.040.9 −0.7 0.5 0.13 0.00 708 MER61F.ERV1.LTR.148.[438] 21 0.28 0.37 1.4−0.8 −0.0 0.13 0.01 709 MER41B- 33 −0.18 0.01 −0.1 0.2 0.0 0.13 0.00 710AluJ/FLAM.Alu.SINE.3444.[7

313 −0.06 −0.04 0.6 0.0 −0.1 0.13 0.00 711 MER5B.MER1_type.DNA.24584.

1582 −0.03 0.01 0.0 0.0 0.2 0.12 0.00 712 MLT1F2- 6 −0.03 −0.00 −0.8−0.4 0.4 0.12 0.01 713 MIRm.MIR.SINE.32156.[90] 2084 −0.01 −0.02 −0.40.4 0.1 0.12 0.00 714 AluYc3.Alu.SINE.1758.[58] 180 0.05 0.08 1.1 −0.5−0.6 0.12 0.00 715 LTR12C- 5 −0.13 0.03 0.4 0.8 −0.5 0.12 0.00 716LTR10B1- 12 0.33 0.26 1.3 −0.6 −0.2 0.11 0.00 717 tRNA- 5 −0.03 −0.160.0 0.6 −0.1 0.11 0.00 718 Charlie1b.MER1_type.DNA.19

163 −0.11 −0.06 −0.4 0.5 −0.3 0.11 0.00 719 AluJo/FLAM.Alu.SINE.2189.[

270 −0.09 −0.07 0.6 −0.3 0.3 0.11 0.01 720 MER96.MER1_type?.DNA.1232.

282 0.01 0.03 −0.1 0.5 0.0 0.11 0.00 721 MER45.Tip100.DNA.678.[86] 5010.04 0.05 0.7 −0.2 0.1 0.10 0.00 722 Looper.PiggyBac.DNA.514.[3

38 −0.13 −0.02 −0.1 0.6 −0.4 0.10 0.00 723 FLAM_A.Alu.SINE.17781.[117

1265 0.00 0.02 0.7 0.0 −0.2 0.10 0.00 724 Zaphod2.Tip100.DNA.715.[19

45 −0.03 0.01 1.0 −0.1 −0.1 0.10 0.00 725 LTR12E.ERV1.LTR.127.[781] 850.21 0.25 0.8 −0.4 0.1 0.10 0.01 726 MLT1G- 8 0.20 0.34 0.7 −0.6 −0.10.10 0.00 727 MER85.PiggyBac.DNA.892.[12

39 −0.07 0.04 −0.3 0.1 0.2 0.09 0.00 728 MER34B- 31 −0.13 0.09 −0.2 0.50.2 0.09 0.00 729 MER4D1- 4 −0.09 0.16 0.2 −0.2 0.4 0.09 0.00 730MER69B.Tip100.DNA.478.[511

41 −0.01 0.09 −0.1 −0.4 0.2 0.08 0.00 731 MER4E- 9 0.05 0.20 0.1 −0.20.3 0.08 0.00 732 LTR24B- 7 0.14 0.17 0.1 −0.1 −0.1 0.08 0.00 733BSR/Beta.Satellite.Satelli

48 −0.02 0.10 1.2 −0.5 0.0 0.08 0.00 734 AluSp/q.Alu.SINE.2568.[100

283 0.09 0.11 1.4 −0.6 −0.0 0.08 0.00 735 L1M3f.L1.LINE.1234.[941] 770.15 0.33 1.8 −0.8 −0.7 0.08 0.00 736 tRNA-Arg- 2 0.39 0.49 0.0 −0.2 0.20.08 0.01 737 Harlequin.ERV1.LTR.610.[15

129 0.33 0.46 1.0 −0.0 −0.6 0.07 0.00 738 HERV15.ERV1.LTR.116.[1879] 27−0.04 −0.09 −0.9 0.3 0.3 0.07 0.00 739 LTR1D- 2 0.60 0.82 0.4 −0.3 0.30.07 0.00 740 body.RNA 1109 −0.03 −0.03 −0.4 −0.4 0.5 0.07 0.00 741LTR65.ERV1.LTR.452.[268] 34 0.12 0.07 0.7 0.0 −0.3 0.07 0.00 742 PABL_A-21 −0.09 0.08 −0.5 0.6 −0.0 0.07 0.00 743 MER65B- 7 −0.15 −0.01 −1.1 0.6−0.0 0.06 0.01 744 MER4E1- 9 0.04 0.18 0.1 −0.4 0.0 0.06 0.00 745LTR13.ERVK.LTR.458.[836] 327 0.25 0.29 1.0 −0.8 −0.0 0.06 0.00 746MER84.ERV1.LTR.345.[286] 43 −0.05 0.05 0.4 0.4 −0.2 0.05 0.00 747MER21A- 21 −0.08 0.06 −0.7 0.5 0.0 0.05 0.00 748 tRNA-Gln- 3 0.26 0.190.0 0.1 0.0 0.05 0.00 749 MLT1F1- 7 0.02 −0.12 −0.4 0.3 0.1 0.05 0.01750 tRNA-Thr- 2 −0.04 −0.23 0.1 0.4 −0.1 0.05 0.00 751Tigger5b.MER2_type.DNA.775

71 −0.10 −0.03 0.6 0.4 −0.4 0.04 0.00 752 HERVE.ERV1.LTR.346.[2130] 192−0.04 −0.08 −0.2 0.2 0.2 0.04 0.00 753 LTR27- 3 −0.06 0.11 1.0 −0.7 −0.00.03 0.00 754 MER95.ERV.LTR.154.[264] 7 −0.18 −0.05 −0.7 0.4 0.2 0.030.00 755 MER41D- 5 0.09 0.15 0.6 −0.7 0.3 0.03 0.01 756MER91.Tip100.DNA.553.[55] 364 0.04 0.03 0.4 0.0 −0.2 0.02 0.00 757tRNA-Gly- 12 −0.12 −0.10 0.4 0.4 −0.1 0.02 0.00 758HERVK14C.ERVK.LTR.81.[1701

13 0.01 0.13 0.4 0.3 −0.1 0.02 0.00 759 MER39B- 7 0.22 0.33 1.0 0.4 −0.70.01 0.01 760 body.scRNA 129 −0.06 −0.02 −0.3 0.2 0.0 0.01 0.00 761MER4B- 63 −0.02 0.12 −0.2 0.0 0.3 0.01 0.00 762MER97b.MER1_type?.DNA.194.

18 −0.09 −0.01 0.0 0.3 −0.1 0.01 0.00 763 LTR8-int.ERV1.LTR.53.[752] 4−0.18 −0.05 0.5 −0.1 0.0 0.01 0.00 764 L3.CR1.LINE.47228.[197] 2942−0.03 0.02 −0.2 0.4 −0.1 0.01 0.00 765 U17.snRNA.snRNA.9.[174] 4 −0.14−0.26 0.0 0.4 −0.3 0.01 0.00 766 LTR71B.ERV1.LTR.209.[426] 28 0.03 0.03−0.0 −0.4 0.1 0.00 0.00 767 Charlie12.MER1_type.DNA.16

17 0.12 0.17 0.6 −0.8 0.2 −0.01 0.00 768 ERVL-C2.ERVL.LTR.54.[807] 4−0.22 0.11 −0.2 0.6 −0.2 −0.01 0.01 769 MER97c.MER1_type?.DNA.1428

91 0.07 0.10 0.6 −0.8 −0.2 −0.01 0.00 770 MER110A- 2 0.34 0.43 0.8 −0.5−0.4 −0.02 0.00 771 LTR13A.ERVK.LTR.182.[795] 98 0.16 0.19 0.0 −0.1 0.0−0.02 0.00 772 FRAM.Alu.SINE.21803.[149] 1895 −0.02 0.01 0.0 −0.1 0.0−0.02 0.00 773 TAR1.telo.Satellite.123.[4

40 −0.01 0.02 0.8 −0.2 −0.3 −0.02 0.00 774 LTR3B_.ERVK.LTR.245.[336] 260.18 0.24 0.3 0.2 −0.4 −0.02 0.00 775 LTR68.ERV1.LTR.341.[293] 9 0.050.22 0.4 −0.7 0.1 −0.04 0.00 776 U8.snRNA.snRNA.30.[110] 1 −0.26 −0.11−0.2 0.7 −0.4 −0.05 0.00 777 AluSq.Alu.SINE.93297.[286] 16445 −0.02 0.030.4 −0.7 0.0 −0.05 0.00 778 MER83- 5 0.02 0.19 0.1 −0.6 0.4 −0.05 0.00779 GSATX.centr.Satellite.58.[

25 −0.12 −0.12 0.4 −0.0 −0.2 −0.06 0.00 780 LTR26B.ERV1.LTR.436.[324] 390.10 0.13 1.4 −0.6 −0.5 −0.06 0.00 781 MER67B.ERV1.LTR.438.[353] 57 0.090.07 −0.4 −1.1 0.4 −0.06 0.01 782 ERVL- 4 0.21 0.24 0.4 −0.6 0.3 −0.060.00 783 HERVFH19.ERV1.LTR.135.[947

20 0.24 0.21 0.1 −0.2 −0.4 −0.06 0.00 784 ERVL-F.ERVL.LTR.459.[601] 200.08 0.19 1.1 −0.5 −0.2 −0.07 0.00 785 MLT1E1A- 2 −0.10 0.02 0.0 0.6−0.4 −0.07 0.00 786 MER106B.MER1_type.DNA.839.

67 0.07 0.10 1.0 −0.0 −0.6 −0.07 0.00 787 AluJ/monomer.Alu.SINE.329.

21 0.06 0.09 0.4 0.1 −0.3 −0.08 0.00 788 MER70B.ERVL.LTR.497.[302] 23−0.09 0.10 −0.6 0.0 0.0 −0.09 0.00 789 tRNA-Met- 2 −0.28 −0.28 0.4 −0.6−0.3 −0.10 0.00 790 LTR52- 23 −0.04 0.00 0.4 −0.0 −0.3 −0.11 0.00 791MER65A.ERV1.LTR.1296.[314] 139 −0.08 −0.00 −0.5 0.6 −0.1 −0.11 0.00 792ALR/Alpha.centr.Satellite.

40 −0.23 −0.08 −0.8 0.9 −0.4 −0.11 0.01 793 MLT1E1- 3 −0.01 0.22 0.6−0.3 −0.3 −0.11 0.00 794 LTR10E- 2 0.49 0.63 0.5 −0.5 −0.2 −0.12 0.00795 body.DNA 24141 −0.03 0.03 0.0 −0.0 −0.3 −0.12 0.00 796 LTR10B- 10.21 0.47 0.8 −0.5 −0.7 −0.12 0.00 797 MLT1G3.MaLR.LTR.596.[291] 51−0.01 0.02 0.4 0.4 −0.3 −0.12 0.00 798 body.MER93B-int 9 −0.24 −0.08 0.0−0.1 −0.2 −0.12 0.00 799 MER51E.ERV1.LTR.240.[301] 27 −0.10 −0.06 0.6−0.5 −0.0 −0.12 0.00 800 tRNA-Ser- 7 0.18 0.07 0.1 −0.1 −0.2 −0.13 0.01801 U6.snRNA.snRNA.1666.[87] 127 −0.04 0.01 −0.3 −0.4 −0.1 −0.13 0.00802 LTR42.ERVL.LTR.287.[361] 27 0.04 0.08 −0.4 −0.1 −0.3 −0.13 0.00 803MER51C.ERV1.LTR.180.[396] 28 0.05 0.06 0.8 −0.6 0.0 −0.13 0.00 804MER51A- 11 0.17 0.17 0.7 −0.5 −0.2 −0.14 0.01 805MER44D.MER2_type.DNA.334.[

30 −0.15 −0.05 0.0 −0.2 −0.3 −0.14 0.00 806 MER7D.MER2_type.DNA.397.[1

16 0.06 0.11 0.7 −0.5 −0.2 −0.14 0.00 807 MER99.DNA.DNA.277.[347] 12−0.14 −0.04 0.7 −0.4 −0.1 −0.15 0.01 808 MIR3.MIR.SINE.70044.[121] 4408−0.01 −0.03 0.0 −0.6 0.2 −0.15 0.00 809 MER97a.MER1_type?.DNA.237.

16 0.05 0.09 0.6 −0.7 −0.2 −0.15 0.00 810 MER104.Tc2.DNA.2013.[149] 1010.01 0.03 −0.4 0.3 −0.2 −0.16 0.00 811 tRNA-Arg- 3 −0.24 −0.37 0.0 −0.5−0.1 −0.16 0.00 812 tRNA-Thr- 5 −0.26 −0.08 −0.5 0.3 −0.4 −0.16 0.00 813tRNA-Arg- 6 0.04 −0.17 0.0 0.0 −0.3 −0.17 0.00 814 tRNA-Gly- 7 −0.12−0.04 0.0 0.0 −0.3 −0.17 0.00 815 LTR60- 4 −0.01 −0.00 0.0 −0.2 −0.3−0.17 0.00 816 MER51B- 30 −0.01 0.21 −0.7 1.0 −0.7 −0.17 0.00 817MER41E.ERV1.LTR.355.[382] 36 −0.09 0.02 −0.4 0.2 −0.3 −0.17 0.01 818MER65D- 1 −0.69 −0.66 0.4 −0.3 −0.4 −0.18 0.00 819BC200.scRNA.scRNA.253.[134

24 0.00 0.04 −0.1 −0.7 0.1 −0.18 0.00 820 LTR18A.ERVL.LTR.250.[313] 300.06 0.10 0.1 −0.1 −0.2 −0.18 0.00 821 MLT2E.ERVL.LTR.1362.[250] 70 0.050.10 −0.3 −0.4 0.3 −0.18 0.00 822 MER31B- 14 −0.06 0.13 −1.1 −0.3 0.3−0.18 0.00 823 MER93b- 9 −0.24 −0.08 −0.2 −0.4 −0.5 −0.19 0.00 824MER52- 3 −0.39 −0.33 0.8 −0.6 −0.1 −0.19 0.00 825 MER87- 3 0.17 0.33 0.0−0.0 −0.5 −0.19 0.00 826 MER101B.ERV1.LTR.239.[304] 14 0.00 0.08 −0.10.0 −0.3 −0.19 0.00 827 tRNA-Leu- 3 0.12 −0.09 −0.4 −1.0 0.3 −0.19 0.00828 tRNA-Val- 2 −0.37 −0.34 0.5 −0.1 −0.5 −0.20 0.00 829LTR58.ERV1.LTR.83.[344] 5 0.11 0.17 0.0 −0.2 −0.2 −0.20 0.00 830tRNA-Tyr- 4 −0.29 −0.34 0.7 −0.4 −0.2 −0.20 0.00 831SATR1.Satellite.Satellite.

236 −0.09 −0.10 0.3 0.1 −0.5 −0.20 0.00 832 MER102b.MER1_type.DNA.3930

271 −0.02 0.00 0.0 −0.4 0.0 −0.20 0.00 833 Tigger5c.MER2_type.DNA.939

27 0.14 0.17 1.2 −0.3 −0.6 −0.21 0.01 834 AluJo/FRAM.Alu.SINE.1339.[

118 0.00 0.03 −0.5 −0.3 −0.2 −0.21 0.00 835 tRNA-Ala- 4 −0.08 −0.27 −0.0−0.2 0.1 −0.22 0.00 836 FLAM_C.Alu.SINE.34861.[125

2632 −0.05 −0.03 0.4 −0.3 −0.5 −0.22 0.00 837 AluSq/x.Alu.SINE.7043.[122

795 −0.03 0.01 −0.5 0.0 −0.1 −0.23 0.00 838 MER52D.ERV1.LTR.576.[932] 640.03 −0.06 −0.5 −0.2 −0.2 −0.23 0.01 839 tRNA-Gln- 2 −0.52 −0.63 −0.3−0.5 −0.4 −0.23 0.00 840 tRNA-Glu- 9 −0.31 −0.40 0.0 −0.5 −0.2 −0.230.00 841 U7.snRNA.snRNA.246.[54] 24 −0.08 −0.06 −0.9 −0.4 0.3 −0.24 0.00842 MER67C- 2 −0.48 0.03 −0.6 −0.5 −0.2 −0.24 0.00 843LTR13_.ERVK.LTR.36.[891] 123 0.17 0.20 −0.2 −0.3 −0.4 −0.24 0.00 844LTR24B.ERV1.LTR.457.[293] 41 −0.01 0.03 0.0 −0.4 −0.3 −0.25 0.00 845LTR10A- 1 0.68 0.38 −0.6 −0.8 −0.2 −0.25 0.00 846HERVK13.ERVK.LTR.64.[1278] 16 −0.23 −0.19 0.0 −0.7 −0.4 −0.25 0.00 847MER4C.ERV1.LTR.1172.[320] 101 −0.00 0.06 −0.0 −0.4 −0.4 −0.26 0.00 848AluYb8.Alu.SINE.68.[161] 15 −0.01 0.03 0.0 −0.4 −0.3 −0.26 0.00 849LTR9-int.ERV1.LTR.51.[921] 4 −0.19 −0.03 −0.4 −0.6 −0.1 −0.26 0.00 850MER112.MER1_type.DNA.3729.

222 −0.02 0.02 0.0 −0.2 −0.3 −0.26 0.00 851 LTR48- 8 −0.05 0.02 −0.4−0.4 −0.2 −0.27 0.00 852 body.Satellite 921 0.05 −0.02 0.4 −0.1 −0.6−0.28 0.00 853 HERVL- 4 0.69 0.65 2.9 −0.4 −1.9 −0.29 0.04 854 LTR19- 40.28 0.42 0.0 0.0 −0.4 −0.29 0.00 855 FLAM.Alu.SINE.1401.[62] 4569 −0.04−0.02 −0.4 0.1 −0.5 −0.29 0.00 856 body.centr 315 −0.09 −0.18 0.5 −0.5−0.4 −0.29 0.00 857 tRNA-Leu- 6 −0.19 −0.35 0.0 −1.0 −0.2 −0.29 0.00 858L1P4b.L1.LINE.275.[1316] 17 0.06 0.22 0.8 −0.6 −0.6 −0.29 0.00 859MER2B.MER2_type.DNA.2351.[

136 −0.06 0.01 0.0 −0.6 −0.4 −0.30 0.00 860 LTR30- 1 −0.37 −0.39 0.0 0.0−0.4 −0.30 0.00 861 LTR23- 16 −0.00 −0.07 −0.4 −0.8 −0.3 −0.30 0.00 862Ricksha_b.MuDR.DNA.115.[59

10 0.23 0.22 0.3 −0.6 −0.4 −0.31 0.00 863 MER84- 7 −0.19 −0.07 −0.7 −0.40.2 −0.31 0.00 864 FordPrefect_a.Tip100.DNA.3

19 −0.05 −0.02 −0.4 0.0 −0.3 −0.31 0.00 865 LTR18B.ERVL.LTR.382.[423] 350.07 0.02 0.4 0.1 −0.7 −0.31 0.00 866 tRNA-Cys- 13 0.12 0.14 0.4 −0.5−0.4 −0.32 0.00 867 MER61B- 12 −0.15 −0.08 0.5 −0.4 −0.6 −0.33 0.00 868L3b.CR1.LINE.7618.[138] 383 0.02 0.04 0.0 −0.7 −0.3 −0.33 0.00 869LTR6A.ERV1.LTR.260.[460] 73 0.09 0.08 0.0 −0.1 −0.6 −0.36 0.00 870LTR6B.ERV1.LTR.149.[506] 44 −0.04 −0.03 −0.4 0.3 −0.6 −0.37 0.00 871tRNA-Ala- 1 0.07 −0.29 0.0 −0.7 −0.4 −0.37 0.00 872 MER41C- 6 0.27 0.16−0.2 −0.5 −0.5 −0.37 0.00 873 MER68- 26 0.27 0.35 1.2 1.3 −1.6 −0.380.03 874 body.MER93b 89 −0.05 −0.00 −0.8 0.1 −0.7 −0.38 0.00 875LTR61.ERV1.LTR.149.[398] 16 −0.16 −0.15 −0.5 −0.6 −0.4 −0.41 0.00 8767SLRNA.srpRNA.srpRNA.937.[

99 −0.00 0.01 −0.3 −0.8 −0.4 −0.42 0.00 877 HERVKC4.ERVK.LTR.63.[885] 13−0.14 −0.06 0.5 −0.1 −0.8 −0.43 0.00 878 LTR29- 1 −0.16 0.02 0.0 −0.8−0.3 −0.43 0.00 879 HERVL18.ERVL.LTR.531.[760] 42 −0.12 −0.10 0.0 −0.7−0.4 −0.44 0.00 880 LTR24- 4 −0.17 0.01 −0.4 −0.1 −0.6 −0.45 0.00 881MER58D.MER1_type.DNA.282.[

21 0.14 0.13 0.4 −0.0 −0.9 −0.48 0.00 882 body.srpRNA 99 −0.00 0.01 0.4−0.3 −0.6 −0.50 0.00 883 MER51D.ERV1.LTR.148.[239] 13 0.09 0.07 0.0 −0.8−0.8 −0.50 0.00 884 Kanga1c.Tc2.DNA.186.[374] 14 −0.04 0.06 −0.5 −0.1−0.7 −0.51 0.00 885 LTR62.ERVL.LTR.312.[425] 38 −0.01 0.03 0.0 −0.3 −0.6−0.53 0.00 886 tRNA-Arg- 6 −0.26 −0.33 0.0 −0.8 −0.6 −0.54 0.06 887tRNA-Asn- 1 −0.55 −0.29 −0.4 −0.7 −0.6 −0.58 0.00 888LTR75.ERVL.LTR.404.[321] 44 −0.02 0.00 0.0 −0.4 −0.8 −0.60 0.00 889HERVK11D.ERVK.LTR.57.[1690

3 −0.38 −0.17 0.4 −0.6 −0.9 −0.62 0.00 890 tRNA-Asp- 9 0.19 −0.01 −0.7−0.6 −0.8 −0.62 0.01 891 L1MB7.L1.LINE.20238.[456] 1775 0.07 0.12 1.6−0.5 −1.4 −0.63 0.03 892 MER4C- 11 −0.01 0.14 0.8 −0.9 −1.1 −0.68 0.01893 LTR35.ERV1.LTR.306.[301] 34 0.07 0.11 0.4 −0.5 −1.0 −0.71 0.00 894MER34C_.ERV1.LTR.1038.[282

72 −0.02 −0.01 0.1 0.1 −1.1 −0.73 0.01 895 LTR10G- 3 0.16 0.18 0.5 −1.7−0.8 −0.74 0.02 896 LTR72B.ERV1.LTR.176.[304] 19 −0.01 0.08 −0.6 −0.3−1.0 −0.75 0.01 897 LTR39- 22 −0.11 −0.00 −0.5 −0.9 −1.1 −0.90 0.03 898LTR45.ERV1.LTR.179.[297] 78 0.04 0.09 1.0 −1.2 −1.4 −0.96 0.01 899Ricksha_0.MuDR.DNA.99.[617

4 −0.42 −0.09 −0.2 −1.2 −1.5 −1.09 0.01 900 LTR6A- 2 0.13 0.15 0.0 −1.2−1.7 −1.27 0.01 901 MER77.ERVL.LTR.2380.[340] 146 −0.03 0.03 0.0 −1.3−2.2 −1.50 0.01

indicates data missing or illegible when filed

B. Example 2 Loss of Epigenetic Silencing in Tumors PreferentiallyAffects Primate-Specific Retroelements

1. Introduction

Close to 50% of the human genome harbors repetitive sequences originallyderived from mobile DNA elements, and in normal cells this sequencecompartment is tightly regulated by epigenetic silencing mechanismsinvolving chromatin-mediated repression. In cancer cells, repetitive DNAelements suffer abnormal demethylation, with potential loss ofsilencing. A genome-wide microarray approach was used to measure DNAmethylation changes in cancers of the head and neck, and to comparethese changes to alterations found in adjacent non-tumor tissues.Specific alterations were observed at thousands of small clusters of CpGdinucleotides associated with DNA repeats. Among the 257,599 repetitiveelements probed, 5 to 8% showed disease-related DNA methylationalterations. In dysplasia, a large number of local events of loss ofmethylation appear in apparently stochastic fashion. Loss of DNAmethylation is most pronounced for certain members of the SVA, HERV,LINE-1P, AluY, and MaLR families. The methylation levels ofretrotransposons are discretely stratified, with younger elements beinghighly methylated in healthy tissues, while in tumors these youngelements suffer the most dramatic loss of methylation. Wilcoxon teststatistics reveal that a subset of primate LINE-1 elements isdemethylated preferentially in tumors, as compared to non-tumoraladjacent tissue. Sequence analysis of these strongly demethylatedelements reveals genomic loci harboring full-length, as opposed totruncated elements, while possible enrichment for functional LINE-1 ORFsis weaker. This analysis indicates that in non-tumor adjacent tissuesthere is generalized and highly variable disruption of epigeneticcontrol across the repetitive DNA compartment, while in tumor cells aspecific subset of LINE-1 retrotransposons that arose during primateevolution suffers the most dramatic DNA methylation alterations.

Herein is a systematic study of DNA methylation changes occurring in therepetitive DNA compartment of squamous carcinomas of the head and neck.In contrast to previous studies, a novel microarray-based approach toobtain discrete DNA methylation data at hundreds of thousands ofindividual repetitive DNA loci in the human genome was used. Extensiveannotation resources for different subfamilies of repeats was then usedto evaluate possible relationships between loss of epigenetic silencingin the context of natural history of cancer, and the evolutionaryhistory of repetitive element sub-compartments in the human genome.

2. Materials and Methods

A specific microarray analysis method permits genome-wide assessment ofDNA methylation status using restriction endonucleases (describedbelow). Among the 339,314 probes in the microarray, 257,599 arededicated to the measurement of the methylation levels of individualmembers of interspersed DNA repeat families. The probes, and the loci towhich they hybridize, can be grouped into families or categories ofprobes and loci based on, for example, repetitive DNA sequence familiesto which the loci belong. Such groups can be used as collective statusbiomarkers.

i. Principle of the DNA Methylation Analysis Method

Multiple displacement amplification (MDA, Dean et al., 2002; Lage etal., 2003; Lage et al., 2005; U.S. Patent Application Publication No.20040063144) is an isothermal amplification method based on randompriming and DNA hyper-branching, catalyzed by a strand-displacing DNApolymerase. The yield of the MBA reaction is strongly influenced by thesize of the DNA used as template (Lage et al., 2005). The dependence ofamplification yield using DNA templates of different size have beensystematically studied, and computational model of the reaction thatfits the experimental data was built. The results of this analysisindicate that the yield of DNA derived from any sequence segment dependson template size, and additionally on the distance of the sequencesegment from the nearest DNA terminus on the template molecule. Otheramplification techniques that have similar effect can also be used. Aspecific cleavage event in a genomic DNA molecule could be detected bymeasuring DNA amplification yield using a DNA microarray, and a probe inthe microarray would be able to measure a local reduction in sequencerepresentation due to cleavage, even if that cleavage event occurred asfar as 1200 bases upstream or downstream from the location of the probe.This property enables the use of probe designs that measure cleavageevents not only in unique DNA sequences overlapping a probe, but alsocleavage events within repetitive DNA sequences that contain CpGdinucleotides, located in the vicinity of a probe of unique sequence,within a window of approximately 2400 bases surrounding the probe.Experimental data is provided that helps to define the approximate sizeof the window that enables probing-at-a-distance.

ii. Microarray Probe Design

DNA probes of unique sequence (uniqueness assessed using merEngine,Healy et al., 2003) were designed to map as closely as possible to everyCpG island in the human genome. The DNA sequences located within awindow of plus or minus 4 kb from loci coding for microRNAs wereexamined, and many of these regions contained small clusters of CpGresidues. A relatively lax “CpG islet” specification was then created,requiring that a region in the genome contain a minimum of 7 CpGresidues, that the ratio of the CG count to the GC content be largerthan 0.53, and that the region be no shorter than 200 bases to benominated as a CpG islet (this is only an example of a specification ofCpG islets; other specifications are disclosed elsewhere herein). Usingthis specification, 453 out of the 532 microRNA loci in the Sangerdatabase (Griffiths-Jones, 2006) are associated with at least one CpGislet within a window of +/−4 kb. By contrast, based on the morerestrictive Takai and Jones definition (2002), the equivalent count ofCpG islands in the vicinity of microRNA loci is 141. The total count ofCpG islets in the human genome using this relaxed specification isapproximately 500,000. A custom microarray containing probes for all CpGislands and CpG islets was designed, in order not to miss DNAmethylation changes that may occur in tumors in CpG-rich regions thatwould not fit the standard CpG island definition. Five broad classes ofCpG islands and CpG islets were probed: promoter associated, unique,non-promoter associated, interspersed repeat associated (Jurka, 1998;Smit, 1996-2004), tandem repeat associated (Benson, 1999), and microRNAlocus associated (Griffiths-Jones, 2006). A subset of the probes werereplicated on the array surface, bringing the total number of probes inthe microarray to 377,000. The coordinates of the probes relevant to theTop 138 repetitive DNA sequence families are shown in Table 15.

Experimental Work Flow for Microarray Analysis

Relative methylation was measured by splitting the DNA sample in twoequal aliquots, and digesting each aliquot with eithermethylation-sensitive or methylation-dependent restrictionendonucleases, respectively, as shown diagrammatically in FIG. 5. Eachof the two digests was amplified by MDA, and then labeled with adifferent dye, followed by mixing after labeling, and processed for DNAmicroarray analysis as described in the Microarray response sectionbelow. The enzymes used to sample DNA methylation have fairly highsampling efficiency when used individually, as ascertained usingsequence analysis. Table 8 documents the theoretical sampling efficiencyof the mixture of the methylation-sensitive endonucleases AciI(recognition site CCGC) and HhaI (recognition site GCGC). The table alsodocuments the sampling efficiency of the methylation-dependentendonuclease McrBC (recognition site Pu^(m)C[N40-3000]Pu^(m)C). Ofcourse, the enzymes do not sample all CpG residues in the genome, butthis limitation is alleviated by the fact that most neighboring CpGresidues in a CpG island tend to have similar methylation status at anygiven time. By theoretical sampling efficiency, it is meant that knowncleavage sites exist in the sequence within or near a CpG island, whichmay or may not be methylated in any given DNA sample, but would cause afluorescence intensity change in either channel of the microarraywhenever a methylation change occurred. Since DNA was sampled using twoseparate digestion reactions, probed loci should be capable of reportingDNA methylation changes based on the presence or absence of cleavage ina single color channel, as well as detecting signal alterations in bothcolor channels, reflecting changes in the combined cleavagesusceptibility to the two classes of endonuclease used. The last columnon Table 8 indicates that if one considers theoretical cleavage sitesfor both sets of enzymes in combination, the potential samplingefficiency increases to 99.9% of all probed CpG islands. The labeled DNAis hybridized to the custom microarray, and subsequently the ratio ofintensities is generated for locus-specific methylation levelsassociated with each probe. In order to illustrate the relationshipbetween the probe location and the location of restriction endonucleasesites in CpG rich domains associated with specific repetitive elements,two detailed maps of interspersed repetitive elements are shown thatwere probed in the microarray. FIG. 6A shows a map of a LINE-1PA3element that was probed using a unique sequence located within 150 basesof the 5′-terminus of the retroelement. The Figure shows the location ofthe CpG islet in the retroelement, as well as the location of allpossible restriction endonuclease sites within and around the element.FIG. 6B shows a similar map, in this case corresponding to a THE1Celement.

Analysis with ASCIIMap can show the locations of the probes and therestriction endonuclease cutting sites in the CpG islands associatedwith these elements. Probes for unique sequences can overlap withrepetitive DNA sequences. The probe design algorithm always ensures thatthe sequence is unique before designing a probe. The apparent paradoxthat a repetitive element may have parts that are unique sequences canbe explained by considering the age of the repetitive elements for whichthe probe is designed. For example, an element of the family MLT1C, 85MYO: over a span of millions of years since it appeared in its originalform in the genome, its sequence have deteriorated from its consensus somuch that although the element can still be classified as MLT1C now(based on the overall structure and certain sequence patterns), itssequences acquired enough random mutations that the probe algorithm canrecognize certain parts within this MLT1C as unique in the genome. Forrepetitive element families that are younger, i.e. the elements thathaven't had evolutionary time to acquire mutations differentiating themfrom their respective consensus, the probe designer most likely designsthe probe within the 100 bases flanking region of the repetitiveelement. Conversely, for the older repetitive elements (20, 30, 40+MYO), the probe designer is able to find regions that have uniquelydiverged from the global consensus of the repeat family.

TABLE 8 Enzymes' efficiency at sampling CpG islands. CpG island near:sampled [%] failed [%] AciI & HhaI Gene 22065 99.84% 36 0.16% LINE 3429799.44% 193 0.56% SINE 178849 99.45% 993 0.55% LTR 22588 99.53% 106 0.47%Satellite 993 99.50% 5 0.50% DNA 8411 99.60% 34 0.40% Other repetitive3988 99.97% 1 0.03% element tandem repeat 674 88.68% 86 11.32% Unique,unclassified 65947 99.38% 409 0.62% genomic sequence Total CpG Islands337812 99.42% 1863 0.58% McrBC[40-3000] Gene 22100 100.00% 1 0.00% LINE34485 99.99% 5 0.01% SINE 179818 99.99% 24 0.01% LTR 22692 99.99% 20.01% Satellite 998 100.00% 0 0.00% DNA 8441 99.95% 4 0.05% Otherrepetitive 3989 100.00% 0 0.00% element tandem repeat 750 98.68% 101.32% Unique, 66338 99.97% 18 0.03% unclassified genomic sequence TotalCpG Islands 339611 99.98% 64 0.02% AciI & HhaI plus McrBC Gene 22101100.00% 0 0.00% LINE 34487 99.99% 3 0.01% SINE 179840 100.00% 2 0.00%LTR 22693 100.00% 1 0.00% Satellite 998 100.00% 0 0.00% DNA 8443 99.98%2 0.02% Other repetitive 3989 100.00% 0 0.00% element tandem repeat 75699.47% 4 0.53% Unique, unclassified 66350 99.99% 6 0.01% genomicsequence Total CpG Islands 339657 99.99% 18 0.01% The table divides theCpG islands based on the type of genomic elements with which they areoverlapping. The “sampled” columns show how many CpG islands in a givengroup contain at least one enzyme recognition motif i.e. theoretically,how many members of the group of CpG islands will a specificendonuclease be able to cleave. The columns labeled “[%]” whichimmediately follow the “sampled” columns, show the percentage of all CpGislands belonging to a specific sub group that have at least one enzymerecognition site, or showing the theoretical capacity or efficiency foran enzyme to cleave the sequences of the particular sub-category of CpGislands. Analogously, the “failed” columns show how many CpG islands donot contain the enzyme recognition motif, which is shown in relativeterms in the column labeled [%] immediately following the “failed”column. The ability of enzymes to cleave particular subgroups of CpGisland in the “sampled” colums, i.e. the sampling efficiency for anenzyme, is shown with respect to AciI and HHaI enzymes (used in a singlebuffer, and thus the numbers in “sampled” columns indicate whether a CpGisland contained either AciI or HHaI motif), McrBC, and, collectively,for all three enzymes.

The experimental data obtained from 74 different probe loci in themicroarray was independently validated by bisulfite sequencing usingeither Sanger sequencing of individual clones of PCR products, or usingthe Sequenom EpiTyper platform, which is based on sequencing oftranscribed RNA by mass spectrometry. Sanger-based analysis wasperformed for a total of 59 different microarray probes. The correlationbetween the microarray read-out and the results of Sanger sequencing wasanalyzed based on the count of CpGs methylated or demethylated in allthe clones of the sequencing result of a locus, the sequences wereclassified as un-methylated, composite or methylated. For 48 of the 59probes, there was agreement between the microarray methylation resultand the bisulfite Sanger sequencing result, for a concordance of 81.4%.The bisulfite sequencing validation analysis produced methylationresults from the microarray analysis, the map position of the probes,and the bisulfite sequencing result for one gene promoter region, oneAluSq element and one AluY element. In these three validationexperiments there is agreement between the microarray result and thebisulfite sequencing data. It should be noted, however, that in the caseof the probe that samples the AluSq element there are neighboringsequences belonging to an MLT1C LTR element, whose methylation statuswill influence the measurements. An effort was made, through extensiveprobe annotation data, to keep track of these complex cases. The resultspresented herein were generated by calculating the average methylationof hundreds, or even thousands of repetitive elements belonging tospecific families of repeats. This averaging process will minimize theinfluence of the surrounding sequence context.

iv. Specimen Sample Acquisition and DNA Preparation

Tumor samples and adjacent non-tumor tissue were obtained through theTissue Procurement Program of the Surgical Pathology Laboratory at YaleNew Haven Hospital. All patients provided informed consent (IRB/HIC#14414). Representative histological sections of all specimens werereviewed to confirm the nature of the sample. After informed consent,oral epithelial cells from subjects with no known risk for oral cancerwere obtained by scraping. DNA from all tissues was obtained usingMasterPure DNA Purification Kit (EPICENTRE). The protocol follows: forevery reaction a mix of 150 μL of Tissue and Cell Lysis solution and 1.5μL of proteinase K from the kit was created. Lysate from about 8 mm³ ofspecimen was collected. The lysate was vortexed every 5 min until thetissue was completely dissolved. The incubation at 65 degrees followedfor 30-60 min. Subsequently 0.5 μL of RNase was added to each tube andincubated for 30 min at 37 degrees. 75 μL of MPC protein precipitationagent was added to the lysed sample. After centrifugation for 10 min at15,000 rpm the supernatant was transferred to a labeled 1.5 mL tube.With 250 μL of isopropanol added to the supernatant the tube wasinverted multiple times. The DNA was then transferred using Pasteurpipet and resuspended in 100 μL of TE (0.1 mM EDTA). The DNA was thenstored for 2 days at 4 degrees. Subsequent quantitation was done usingPicoGreen fluorescence.

200 ng genomic DNA extracted from the head and neck tumor or thecorresponding non-tumor adjacent tissues were digested by two sets ofrestriction enzymes respectively. One genomic sample was digested byMcrBC (New England Biolabs), the other was digested by AciI and HhaI(New England Biolabs). 20 units of each enzyme were used to set up 45 μlreaction in the recommended buffer (McrBC: 50 mM NaCl, 10 mM Tris-HCl,10 mM MgCl2, 1 mM DTT supplemented with 100 μg/mL BSA, and 5 mM GTP;AciI and Hha: 50 mM Tris-HCl, 100 mM NaCl, 10 mM MgCl2, 1 mM DTTsupplemented with 100 μg/mL BSA). Reactions were incubated at 37 C for 6hours and then boosted with an additional 10 units of the correspondingenzyme for another 12 hrs, and finally inactivated at 65 C for 20minutes. One aliquot of each digested genomic DNA (20 ng) was subjectedto whole genome amplification respectively using REPLI-G kit (Qiagen)with 8 hours incubation at 30 C. The amplified DNA sample was thenpurified by QIAEX II kit (Qiagen) with slightly modified protocol (3instead of 2 washes with PE buffer and finally eluted in water ratherthan EB buffer). 4 μg of the purified genomic DNA sample was submittedto Nimblegen for labeling and hybridization.

v. Microarray Response

A control experiment defined the longest distance from a probe at whichendonuclease cuts can be measured using the microarray method. DNA wascleaved with PmeI, and processed by isothermal whole genomeamplification followed by microarray analysis using uncleaved, amplifiedDNA as a reference channel. All probes containing a single predictedPmeI cut, and not bounded by another cut within a distance of +−40 kbwere plotted at x=0 in an xy plot. Other probes proximal to the cut site(upstream as well as downstream) were plotted according to theirposition in the x axis. The ratio of the two microarray channels(cleaved and uncleaved DNA) was plotted in the y axis. The deflection ofthe y axis in the xy plot indicates that a single endonuclease cutproduces large changes in the ratio (y) within a window of +/−3.0 kb,with the most pronounced deflection of the ratio occurring within awindow of +/−1.2 kb.

vi. Validation of Microarray-Based Observations Using Bisulfite DNASequencing

a total of 74 probe loci that showed DNA methylation changes in tumorswere selected, and the DNA methylation status was examined usingbisulfite DNA sequencing across a total of 12 experiments, for a totalof 207 probe validation data points. DNA sequencing was performed usingtwo different experimental approaches. In the first approach,bisulfite-treated DNA was used to amplify by PCR the genomic regions ofinterest, and the PCR amplicons were cloned. Individual clones wereprocessed for Sanger sequencing in both strand orientations. In thesecond approach, bisulfite-treated DNA was used to amplify by PCR thegenomic regions of interest, and the PCR amplicons were then transcribedto generate complementary DNA using reagents provided by Sequenom, Inc.as part of their EpiTYPER kit. The RNA was then cleaved withribonuclease A, and subjected to mass spectrometry analysis. Usingsoftware provided by Sequenom, the mass spectrograms were processed togenerate a fractional value of DNA methylation between 0.0 and 1.0. Whenmultiple probes associated with a single CpG island were averaged, theconcordance of the microarray calls and the bisulfite sequencing resultswas 87.6%.

vii. Plotting the Data

All members of each phylogenetic branch of the repetitive elementsubfamilies were grouped together based on their sequence homology andestimated evolutionary age. The average of the individual log 2methylation values were calculated for all microarray probes belongingto each branch, and plotted these subset-specific values across allexperiments. A fourth class of experiments included three technicalreplicates of a microarray analysis performed using DNA from humansperm.

a. Per-Experiment Plots

Given that each probe in the microarray is annotated with itsassociation to the proximal genomic elements (repetitive elementcategory, gene, miRNA) for every experiment in the library, a query isissued to retrieve a subset of probes in the vicinity of a specificelement. The set of probes (from which the subset of probes areretrieved) are complementary to unique sequences in loci containing CpGislands or CpG islets the selection of which is described elsewhereherein. A set of values from the probes in the retrieved subset ofprobes is then averaged per experiment and plotted accordingly (note,instead of average, any other function can be applied here). This isrepeated for every experiment and for every category requested. FIG. 11Ais an example of this plot for 4 categories of genomic compartments.Contrast with FIG. 11B, which shows the same information in per-categoryview. A standard boxplot implementation included in R programminglanguage was embedded in a custom script to generate these plots.

b. Per-Category Plots

An alternative to the plots described above are the per-category plots,devised to simplify the presentation of information especially when manycategories of repetitive elements are to be plotted. For these plots,once an average of a given category of probes is calculated for allexperiments, a box-and-whisker plot is then generated to summarize thesevalues for experiment subsets: normal (top), non-tumor adjacent, tumorand sperm (bottom). FIG. 11B is an example of this plot for 4 categoriesof genomic compartments. Contrast with FIG. 11A, which shows the sameinformation in per-experiment mode.

A standard boxplot implementation included in R programming language wasembedded in a custom script to generate these plots.

c. On Order of Experiments

The experiments are always grouped (top to bottom) into normal,non-tumor adjacent, tumor and sperm-replicate classes. The order ofexperiments across all plots (unless stated otherwise) is kept constant.The order has been established based on the difference of mostinformative category of L1P (Table 9) versus the most stable across allexperiments categories of repetitive elements: AluSq and DNAtransposons. FIGS. 10A and 10B depicts the element values used.

TABLE 9 A summary of an enrichment analysis. A summary of an enrichmentanalysis where a set of probes significantly differentiating tumors andnon-tumor adjacent experiments was chosen using Wilcoxon non-parametrict.test and Benjamini-Hochenberg FDR correction to arrive at 15,587probes. Probe categories defined by their proximity to a specificcategory of repetitive element were then checked for their enrichment insignificant probes. The expected number is calculated based on the totalnumber of probes in the array 339,314, and the total number of probes ina given category. The enrichment is then confirmed using hyper geometrictest. Table sorted based on p-values, from most significant to leastsignificant. # of probes significantly differentiating non-tumor totaladjacents and number of # of # of tumors (no expected at probes inhyperGeometric genomic probed category pairs) random enrichment categoryp-val repeats repeats L1P 800 18.9 42 8,000 3.18E−151 1,589 8,681 L12913 452.8 6 52,747 8.70E−139 895,230 64,191 LINE 3699 829.7 4 76,1072.08E−101 1,354,049 92,711 L1PA3 223 0.8 295 1,150 9.25E−96 10,281 1,146AluY 3211 680.7 5 71,931 7.80E−48 135,761 72,224 SINE 7232 3,919.1 2183,877 2.42E−39 1,744,457 245,936 L1PA2 121 0.3 382 888 1.06E−36 4,666874 L1PA4 96 0.2 572 593 9.76E−36 11,462 602 L1M 1891 227.7 8 40,8607.82E−34 11,466 50,879 Alu 6390 3,073.2 2 163,190 2.17E−28 1,160,276205,535 LTR 1539 151.1 10 33,309 6.57E−27 641,720 40,016 L1HS 56 0.1 961353 2.11E−21 1,696 357 L1PA5 47 0.1 812 418 1.73E−12 10,904 428 ERV1 61924.2 26 13,292 7.68E−12 175,007 16,078 L1MC 449 12.6 36 9,506 9.72E−1016,426 11,128 MaLR 663 29.0 23 14,865 1.60E−09 327,397 16,710 ERVL 2874.9 59 5,763 9.40E−09 128,284 6,401 L1P1 21 0.0 2,247 151 2.34E−08 2,860149 L1MA1 41 0.1 691 491 2.29E−07 3,940 525 L1PA7 31 0.0 1,019 3334.86E−07 12,334 343 L1MCc 27 0.0 1,234 275 7.76E−07 6,889 340 L1ME3 1701.7 103 3,304 1.16E−06 7,572 3,897 MLT1A 100 0.5 193 1,756 2.60E−068,650 1,929 U3 19 0.0 1,984 171 3.46E−06 228 103 L1MC3 55 0.1 411 8264.84E−06 12,792 963 L1MA9 47 0.1 506 671 5.48E−06 14,394 745 L2 104880.3 13 26,009 1.03E−05 403,973 27,360 LTR7 42 0.1 568 597 1.38E−052,349 610 L1PA16 39 0.1 625 543 1.62E−05 13,098 589 L1MD 160 1.5 1043,250 2.34E−05 10,847 3,749 L1ME1 98 0.5 186 1,821 3.01E−05 26,938 2,131L1ME3B 91 0.4 202 1,677 4.05E−05 27,528 1,993 L1MC1 49 0.1 437 7775.63E−05 11,868 864 THE1D 34 0.0 704 482 6.96E−05 12,381 512 L1MA2 250.0 1,054 322 1.06E−04 6,911 347 L1M4 108 0.7 159 2,131 1.37E−04 19,5042,520 L1PA15 28 0.0 884 384 1.43E−04 8,233 429 L1PB 70 0.3 268 1,2641.43E−04 1,520 1,379 AluSc 504 18.0 28 12,148 1.88E−04 48,789 11,969ERVK 53 0.1 372 911 2.35E−04 10,461 1,019 L1P4 23 0.0 1,116 304 2.67E−045,156 328 L1M4c 29 0.0 806 421 3.00E−04 7,787 504 L1MB1 21 0.0 1,257 2703.05E−04 5,670 299 LTR2 46 0.1 440 771 3.11E−04 847 861 L1PA8 27 0.0 881385 3.38E−04 7,715 405 MIR 1517 176.1 9 39,390 3.63E−04 584,181 40,401L3 170 1.9 92 3,702 4.11E−04 47,228 3,473 L1MA6 17 0.0 1,593 2136.72E−04 4,693 238 L1MA4A 21 0.0 1,170 290 7.97E−04 5,823 334 Tigger3b26 0.0 875 388 8.30E−04 4,998 434 HERVH 25 0.0 917 370 8.89E−04 5,774461 LTR33A 15 0.0 1,844 184 9.61E−04 3,521 174 MLT1A1 23 0.0 1,019 3339.71E−04 6,611 371 L1M2 29 0.0 749 453 9.82E−04 9,352 524 MER57A 20 0.01,229 276 9.95E−04 2,633 323 L1M4b 27 0.0 816 416 1.11E−03 7,423 504L1MA4 42 0.1 463 733 1.15E−03 8,983 824 L1MA10 21 0.0 1,131 300 1.23E−035,419 313 Tigger1 45 0.1 422 805 1.35E−03 11,928 951 LTR33 38 0.1 517656 1.49E−03 9,302 668 L1MCb 11 0.0 2,759 123 1.51E−03 2,863 147 MER9417 0.0 1,475 230 1.61E−03 4,680 232 L1PA13 25 0.0 872 389 1.80E−0310,722 410 MLT1E2 15 0.0 1,731 196 1.85E−03 3,960 213 L1PB1 30 0.0 683497 2.09E−03 11,421 532 MER39 20 0.0 1,124 302 2.96E−03 3,125 339 AcHobo56 0.2 311 1,092 3.05E−03 18,762 1,106 MLT1J 64 0.2 265 1,280 3.12E−0315,375 1,332 L1ME3A 56 0.2 309 1,097 3.35E−03 16,330 1,269 L1MD1 27 0.0752 451 3.53E−03 6,126 523 MER4D 16 0.0 1,482 229 3.67E−03 1,275 259MER103 22 0.0 967 351 4.04E−03 6,812 348 MSTD 23 0.0 910 373 4.23E−037,421 412 LTR12_(—) 11 0.0 2,406 141 4.67E−03 664 136 THE1C 20 0.0 1,064319 5.52E−03 9,731 330 MLT1A0 51 0.2 335 1,014 6.23E−03 20,156 1,102L1PA10 17 0.0 1,290 263 6.59E−03 6,962 271 MLT1J2 21 0.0 984 3456.60E−03 7,867 331 L1MD2 44 0.1 395 858 7.07E−03 12,388 990 L1MA8 29 0.0650 522 7.63E−03 9,992 576 MER57A- 9 0.0 2,900 117 9.06E−03 1,965 146int Mariner 47 0.1 361 941 9.07E−03 16,055 984 MER4A 19 0.0 1,084 3139.07E−03 1,084 366 MIR3 213 3.2 66 5,136 1.05E−02 70,044 4,603 LTR9 180.0 1,139 298 1.10E−02 1,919 314 MLT2B1 12 0.0 1,917 177 1.11E−02 4,186191 L1PA6 13 0.0 1,722 197 1.13E−02 5,617 201 L1MEe 37 0.1 471 7201.13E−02 12,492 890 THE1B 33 0.1 539 630 1.17E−02 22,106 659 MLT2A2 80.0 3,263 104 1.20E−02 3,754 106 HERV16 11 0.0 2,108 161 1.28E−02 4,493183 L1MEc 56 0.2 288 1,179 1.35E−02 21,328 1,421 L1MA3 25 0.0 741 4581.41E−02 8,131 490 LTR16B 12 0.0 1,834 185 1.55E−02 3,456 183 PiggyBac 90.0 2,630 129 1.71E−02 2,068 138 DNA 948 69.9 14 25,027 1.84E−02 386,46628,225 CR1 135 1.3 106 3,198 2.00E−02 54,846 3,185 MER50 19 0.0 998 3402.05E−02 2,576 390 MER2_type 206 3.1 67 5,048 2.05E−02 81,748 5,863MLT1E 30 0.1 577 588 2.06E−02 3,378 660 MER2 287 6.1 47 7,202 2.25E−028,174 8,171 L1P3 11 0.0 1,928 176 2.41E−02 4,518 184 MIRm 108 0.8 1342,528 2.45E−02 32,156 2,288 L1M1 25 0.0 704 482 2.49E−02 10,118 540 LTR1165 1.9 85 4,006 2.54E−02 1,396 4,070 MER6 84 0.5 177 1,922 2.55E−02 9262,123 MER8 41 0.1 393 864 2.77E−02 1,884 891 ERVL-E 21 0.0 855 3972.84E−02 9,525 453 L1PB4 17 0.0 1,095 310 2.99E−02 6,330 328 MER39B 70.0 3,294 103 3.07E−02 1,166 113 LTR67 17 0.0 1,091 311 3.07E−02 6,289306 FAM 31 0.1 537 632 3.08E−02 4,424 525 MLT1I 26 0.0 655 518 3.27E−0211,191 533 MER4A1 13 0.0 1,495 227 3.34E−02 2,150 267 L1PA14 9 0.0 2,356144 3.35E−02 3,561 160 MLT2B3 8 0.0 2,693 126 3.63E−02 2,966 126 MLT1F33 0.1 490 692 3.84E−02 4,498 769 L1MC5 67 0.3 220 1,544 4.42E−02 20,4121,780 AluYg 19 0.0 915 371 4.47E−02 111 363 L1MA5 20 0.0 857 3964.67E−02 4,086 435 MIRb 736 42.4 17 19,543 4.77E−02 278,083 19,026 MADE29 0.0 2,203 154 4.91E−02 2,609 139 LTR49 9 0.0 2,203 154 4.91E−02 1,406182

d. Shannon Information Value

The order of categories in the legend of per-experiment plot and thecategory-list of per-category plots is not accidental. The categoriesare ordered based on the extent of their variation using Shannoninformation content metric (available atcm.bell-labs.com/cm/ms/what/shannonday/shannon1948.pdf). Only Normal andTumor experiments were used to establish the order of categories.Specifically, once the per-category values (average methylation forFIGS. 7A and 7B) across normal (10 values per category) and tumor (33values per category) experiments are calculated, a Shannon informationmeasure function is applied to the distribution of 43 values.

The Shannon Information measure is a foundation of modern Informationtheory and was devised to estimate the minimum number of bits needed toencode sentence or a string of characters of text, if one wanted totransmit such string digitally. The information measure takes intoconsideration the frequency of the symbols. As a result, a string madeup of the same symbol would require a very simple encoding using one bitof information, whereas a string made up of all the letters in thealphabet would need considerably more bits to represent all the lettersunambiguously.

Analogously, the 43 values can be considered as the individual lettersof Shannon's string. Shannon's entropy measures how dissimilar the 43values are from each other. The more dissimilar, the more information isin the set.

The categories are listed from lowest information content (top) to thehighest information content (bottom). The most informative categoriesare highlighted. A custom R script was used to generate the plots andcalculate the information content.

3. Results and Discussion

i. Methylation Patterns of Major Classes and Families of DNA Repeats

The DNA methylation profiles of 33 tumors and 17 non-tumor adjacenttissue samples obtained from patients with head and neck squamouscarcinoma (HNSCC) were analyzed. DNA methylation profiles were alsogenerated from the buccal epithelia of 10 normal individuals, whichserved as controls. In addition, an analysis of sperm DNA was performedin technical triplicate to assess the reproducibility of the microarrayresults. An average methylation value for selected subsets of “genomicprobe compartments” was calculated. An exemplary profile of averagemethylation for two extremely different genomic probe compartments canbe found in FIG. 11A, which shows DNA methylation values for all SVAelements as well as methylation values for all genes for each of thetissue sample experiments. Then all average metrics per tissue classwere combined, generating a distribution of averages, shown in FIG. 11B.FIGS. 7 and 8 all use a box and whiskers distribution plot to displayDNA methylation trends for different classes of repetitive elements.

FIG. 7A depicts the distribution of all averages of DNA methylationvalues across all experiments for each of the major repetitive elementfamilies (as summarized by Mandal and Kazazian, 2008). Twoprimate-specific families of repeats, AluY (Alu) and LIP (LINE-1), werealso included and will be discussed at length in the ‘methylation of Aluelements’ and ‘methylation of LINE-1 elements’ sections, respectively.Gain of methylation is represented by values on the negative scale ofthe x-axis, and loss of methylation by values on the positive scale,towards the right side of the plots. Each subsection of the plotfeatures the same families of repetitive elements in the same order fornormal, non-tumoral adjacent, tumor and replicated sperm experiments.The order of repetitive families was established based on theinformation content (Shannon entropy metrics) of the methylation valuesamong normal and tumor experiments (see Materials/Methods section‘Plotting the data’). The 5 most “informative” families of repeats areplotted towards the bottom of the plot's subsection and highlighted. Themost informative is a primate-specific subset of probes for asubcategory of LINE-1. Annotation provided by RepBase (Jurka, 1998)allowed for the investigation of subclasses of repetitive elements ingreater detail. The section on ‘methylation of LINE-1 elements’ expandson the analysis of L1P elements delving into finer subcategories ofthese repetitive elements.

An alternative way of examining the DNA methylation data is to comparemethylation levels that have been normalized with respect to the valuesof the non-tumor adjacent tissue, as shown in FIG. 7B. Thisadjacent-tissue-normalized plot makes it clear that the averagemethylation levels of several classes of repetitive elements in tumorsare not dramatically different from those in the non-tumor adjacentmaterial, while the normal buccal mucosa shows much higher methylation,especially for SVA, ERV, ERVK, and UP elements. Remarkably, it appearsthat the cumulative differences of loss of methylation for certainclasses of elements such as SVA are as large between the normal and thenon-tumoral adjacent tissue as they are between tumors and normal tissuesamples. Previous reports in the head and neck cancer literature (Smithet al., 2007) indicate that normal buccal epithelium of individualsexposed to cigarette smoke have abnormally reduced levels of globalmethylation of LINE-1 elements, as determined by bisulfite sequencing ofLINE-1 PCR amplicons. Even lower methylation levels were reported bythese authors in cancer tissues, with advanced tumors (stages II and IV)showing the lowest methylation levels. It has also been reported that incolon cancer patients, non-tumor adjacent regions of colonic mucosa showsignificant loss of methylation of LINE-1 retrotransposons as comparedto colonic mucosa of normal individuals (Suter et al., 2004), whilecolon cancer tissue shows even more pronounced loss of methylation.FIGS. 7A and 7B indicate that various subcategories of larger repetitiveelement families contribute disproportionately to the DNA methylationchanges of their parent category. The following sections adhere to theplot style in FIG. 7A, which most accurately represents the raw datagenerated by the microarray analysis, and also shows the best fit to theDNA methylation values obtained independently by bisulfite sequencing ofPCR products of specific probed loci. For example, in FIG. 7A it isclear that MIR elements (representing DNA transposons), are relativelyunmethylated in normal mucosa, in non-tumor adjacent tissue, and insperm. Notably, only in tumor tissue is a gain of methylation of theseDNA transposons observed. These interesting relative methylationrelationships are more difficult to observe, and less indicative of theactual methylation levels, as displayed in FIG. 7B due to the effects ofnormalization.

The following sections will focus on exploring in greater detail thedynamics of methylation patterns among various sequence sub-compartmentsof a given class of repetitive elements. To facilitate navigationthrough the perhaps unfamiliar nomenclature that identifies the varioussubclasses of elements, four tables are included that list the differentsubclasses within a class, in chronological order of estimatedevolutionary age. These tables (Tables 10A through 10D) can be found inthe supplementary materials. A table for the ERV retroelements is notincluded because the evolutionary ages and phylogenetic relationships ofthese elements are still a subject of investigation and revisedannotation. To facilitate additional exploration of the data sets, themethylation levels can be grouped by subclass of repetitive element,rather than by tissue type (as in FIGS. 7 and 8).

TABLE 10A A compilation of observations about ages of lineages withinfamilies of repetitive elements. Estimated age of Element appearance inthe Element Family subfamily genome (MYA) references MaLR MLT1d 100 FIG.4 in Smit, 1993 MaLR MLT1c 85 FIG. 4 in Smit, 1993 MaLR MLT1b 80 FIG. 4in Smit, 1993 MaLR MLT1a 77 FIG. 4 in Smit, 1993 MaLR MSTb 75 FIG. 4 inSmit, 1993 MaLR MSTa 60 FIG. 4 in Smit, 1993 MaLR THE1c 55 FIG. 4 inSmit, 1993 MaLR THE1b 50 FIG. 4 in Smit, 1993 MaLR THE1a 45 FIG. 4 inSmit, 1993

TABLE 10B A compilation of observations about ages of lineages withinfamilies of repetitive elements. Estimated age of Element appearance inthe Element Family subfamily genome (MYA) references Alu FLA 112 Table 3in Kapitonov and Jurka, 1996 Alu Jo 44, 81 Table 3 in Kapitonov andJurka, 1996, Table S1 in Pace and Feschotte, 2007 Alu Jb 42, 81 Table 3in Kapitonov and Jurka, 1996, Table S1 in Pace and Feschotte, 2007 Alu S48 Table 3 in Kapitonov and Jurka, 1996 Alu Sx 28, 37, 44, 55 Table 3 inKapitonov and Jurka, 1996, FIG. 2 in Batzer and Deininger, 2002, TableS1 in Pace and Feschotte, 2007, Table 2 in Xing et al. 2004 Alu Sg 23,31, 34, 40 Table 3 in Kapitonov and Jurka, 1996, FIG. 2 in Batzer andDeininger, 2002, Table S1 in Pace and Feschotte, 2007, Table 2 in Xinget al. 2004 Alu Sq 25, 39, 44 Table 3 in Kapitonov and Jurka, 1996,Table S1 in Pace and Feschotte, 2007, Table 2 in Xing et al. 2004 Alu Sp28, 37 Table 3 in Kapitonov and Jurka, 1996, Table 2 in Xing et al. 2004Alu Sc 22, 30, 35 Table 3 in Kapitonov and Jurka, 1996, Table S1 in Paceand Feschotte, 2007, Table 2 in Xing et al. 2004 Alu Sb 19 Table 3 inKapitonov and Jurka, 1996 Alu Y 16, 35 FIG. 2 in Batzer and Deininger,2002, Table S1 in Pace and Feschotte, 2007 Alu Yd 15 Table 2 in Xing etal. 2004 Alu Ye5 12 Table 2 in Xing et al. 2004 Alu Yb8 11 FIG. 2 inBatzer and Deininger, 2002 Alu Ya5 2, 11 FIG. 2 in Batzer and Deininger,2002, Table 2 in Xing et al. 2004 Alu Yc1 2, 5 FIG. 2 in Batzer andDeininger, 2002, Table 2 in Xing et al. 2004 Alu Ya5a2 5 FIG. 2 inBatzer and Deininger, 2002 Alu Yg6 3 Table 2 in Xing et al. 2004 Alu Yb92, 5 FIG. 2 in Batzer and Deininger, 2002, Table 2 in Xing et al. 2004Alu Ya8 1 Table 2 in Xing et al. 2004

TABLE 10C A compilation of observations about ages of lineages withinfamilies of repetitive elements. Estimated age of Element appearance inthe Element Family subfamily genome (MYA) references SVA A 10-17 Table 2in Wang et al. 2005 SVA B 11-12 Table 2 in Wang et al. 2005 SVA C 10-11Table 2 in Wang et al. 2005 SVA D 9.4-9.5 Table 2 in Wang et al. 2005SVA E 2.4-4.5 Table 2 in Wang et al. 2005 SVA F 2.7-3.6 Table 2 in Wanget al. 2005

TABLE 10D A compilation of observations about ages of lineages withinfamilies of repetitive elements. Estimated age of appearance ElementElement in the genome Family subfamily (MYA) references L1PA L1PA1 3.1Table 1 in Khan et al. 2006 L1PA L1PA2 7.6 Table 1 in Khan et al. 2006L1PA L1PA3 12.5 Table 1 in Khan et al. 2006 L1PA L1PA4 18.0 Table 1 inKhan et al. 2006 L1PA L1PA5 20.4 Table 1 in Khan et al. 2006 L1PA L1PA626.8 Table 1 in Khan et al. 2006 L1PA L1PA7 31.4 Table 1 in Khan et al.2006 L1PA L1PA8 40.9 Table 1 in Khan et al. 2006 L1PA L1PA8A 41.7 Table1 in Khan et al. 2006 L1PA L1PA10 46.4 Table 1 in Khan et al. 2006 L1PAL1PA11 53.3 Table 1 in Khan et al. 2006 L1PA L1PA13B 59.8 Table 1 inKhan et al. 2006 L1PA L1PA12 59.7 Table 1 in Khan et al. 2006 L1PAL1PA13A 59.9 Table 1 in Khan et al. 2006 L1PA L1PA14 60.6 Table 1 inKhan et al. 2006 L1PA L1PA15 70.5 Table 1 in Khan et al. 2006 L1PAL1PA16 79.7 Table 1 in Khan et al. 2006 L1PA L1PA17 101.1 Table 1 inKhan et al. 2006 L1PB L1PB1 46.7 Table 1 in Khan et al. 2006 L1PB L1PB258.2 Table 1 in Khan et al. 2006 L1PB L1PB3 73.5 Table 1 in Khan et al.2006 L1PB L1PB4 96.0 Table 1 in Khan et al. 2006 L1MA L1MA1 61.6 Table 1in Khan et al. 2006 L1MA L1MA2 65.8 Table 1 in Khan et al. 2006 L1MAL1MA3 68.1 Table 1 in Khan et al. 2006 L1MA L1MA4 102.3 Table 1 in Khanet al. 2006 L1MA L1MA5 98.6 Table 1 in Khan et al. 2006

ii. Methylation of MaLR Elements

Since observing that AluY and UP, two primate-specific subfamilies ofrepeats scored higher using the information content statistic than theirrespective (and all-inclusive) parents, a relatively well-annotatedfamily tree of “mammalian apparent LTR retrotransposons” (MaLR) wasinvestigated (Smit, 1993). An analysis involving specific subsets ofMaLR is shown in FIG. 8. Here, again, the youngest members of the MaLRelements, THE1A, THE1B, THE1C, MSTA, and MSTB which only exist insimians and humans, are methylated in normal tissue but show marked lossof methylation in most tumors. Older MaLR subfamilies are lessmethylated in normal tissue, and show less striking loss of methylationin tumors. It is intriguing that among the younger families, THE1A andTHE1B retroelements, which were observed to be demethylated in mostnon-tumoral adjacent tissue as well as tumors, have been identified askey sequence attributes of human recombination hotspots (Myers et al.,2005, 2008). The possible contribution of these subfamilies ofdemethylated MaLR elements to recombinational events in tumors is aninteresting subject for future investigation.

iii. Methylation of Alu Elements

Alu elements are the most abundant class of repetitive elements in thehuman genome with over one million copies and spanning over 30 lineages.The most detailed published analysis of Alu DNA methylation in normalcells and cancer cells was reported by Rodriguez et al. (2008). Theseauthors targeted unmethylated SmaI sites within Alu sequences, and foundthat normal colon epithelial cells contain a subpopulation ofundermethylated Alus, while in tumor cells the number of unmethylatedAlu sequences is doubled. They also reported an increased methylation ofthe younger Alu subfamilies. The microarray-based analysis includes onlythose Alu lineages for which more than 200 unique locations were probed.As observed for other classes of elements, the younger elements (AluY)are more highly methylated in normal adult tissues, yet are suffering agreater loss of DNA methylation in many tumors. Interestingly, theoldest Alu elements remain methylated in sperm, while the younger onesshow loss of methylation in this tissue. The most informative amongnormal and tumor tissues lineage of Alu's is AluYb. Coincidentally, itis also the most active of all Alu lineages and found primarily in humangenomes (Jurka, 1993; Carter et al., 2004). AluYg, the next mostinformative lineage remains relatively unknown. Among other, lessinformative lineages, the middle-age AluS families lose methylation intumor tissue, while the members of the oldest, AluJ lineages remainmethylated at an intermediate level, and constant in all 4 tissue types.

iv. Methylation of ERV Elements

Endogenous Retrovirus (ERV) Families are a heterogeneous group ofsequences with over 60 lineages according to RepBase (Jurka, 1998).There are reports of ERV sequences being involved in extensivechromosomal rearrangement during the last 30 million years in primateevolution (Romano et al., 2006). Per-lineage analysis pertaining to themethylation pattern of ERV was assessed. Similarly to MaLR and Aludiscussed above, Human Endogeneous Retrovirus (HERV) families appearheavily methylated in the normal tissues. The gradual loss ofmethylation is apparent for HERVH and HERV17 families. To an extent, themethylation levels of HERVE and KERVK also vary among normal, tumors andnon-tumoral adjacent tissues. So far, for MaLR, Alu and ERV families ofancient repetitive elements, predating the mammalian radiation, themicroarray DNA methylation analysis indicates that young, primatespecific lineages appear more susceptible to de-methylation in diseasethan other, older lineages.

v. Methylation of SVA Elements

A similar analysis was performed for SVA elements, which have beenextensively mobilized in the human genome after the divergence ofhominids from chimpanzees (Xing et al., 2007; Wang et al., 2007;Macfarlane and Simmonds, 2004). SVA elements consist of a combination ofsequences derived from other retroelements (Babushok and Kazazian, 2007)and are known to be non-autonomous, depending on LINE-1 elements formobilization. Wang et al. (2005) have estimated the evolutionary age ofdifferent subfamilies of SVA elements, named SVA-A through SVA-F. Thisanalysis reveals that the youngest SVA subfamilies show an unusualrelationship between evolutionary age and the level of dysregulation.SVA-F elements, which are human specific, and only 3 MY old, aresignificantly less methylated than other, older subfamilies, and theirmethylation level does not change much in different samples, with theexception of sperm, where these elements show loss of methylation. Onthe other hand, the SVA-A elements, which are the oldest SVA subfamily(16.81 MY), are strongly methylated in normal oral tissues, but theirloss of methylation is strikingly variable among different samples, withtumors showing the greatest level of variation. Thus, the magnitude andtrends of DNA methylation changes for the youngest SVA elements seems todiverge from the patterns observed for AluY, MaLR, and ERV elements. Thedramatic DNA methylation dysregulation affecting most SVA subfamilies innon-tumoral adjacent tissue is particularly striking.

vi. Methylation of LINE-1 Elements

Lineages of the LINE-1 family were investigated. Categories which couldbe probed in at least 100 unique genomic loci. Comparing the valuesacross the four classes of experiments, it is apparent that younger,primate specific classes of LINE-1 elements (LINE-1PA3 (L1PA3) andLINE-1PA4 (L1PA4) and LINE-1PA5 (L1PA5), none of which exist in thebaboon or marmoset) are more strongly methylated in normal tissue, andsuffer more dramatic losses in DNA methylation in tumors and sperm.However, similarly to the observations for SVA subfamilies, the newestLINE-1 families that are strictly human specific (L1PA2, L1HS, FullLength active LINE-1 (Penzkofer et al., 2005)) are not as highlymethylated in normal tissue, and not as dramatically demethylated intumorigenesis as the longer-established lineages, the primate-specificLINE-1PA subfamilies.

It is relevant to explore potential correlations or anti-correlationsamong the DNA methylation metrics within individual experiments. Withthis question in mind, FIG. 9 reports methylation levels in individualexperiments for the family of MIR repeats, as well as the family of L2repeats, as compared to L1PA3 and L1PA4 methylation levels. The dataillustrates completely distinct and sometimes opposing trends in theirlevels of methylation, demonstrating that the observed metrics for theL1PA methylation levels are not due to normalization artifacts. In mostcases the youngest members of each retrotransposon family are stronglymethylated in normal buccal tissues, as shown by their negative valuesfor all 10 samples from healthy adults. In tumors, the correspondingretroelement families shift dramatically to a relatively unmethylatedstate, as shown by the predominantly positive values. In the adjacentnon-tumor tissue, the methylation level is variable, reflectingdifferent degrees of epigenetic dysregulation in these tissues amongdifferent patients. These results underscore the fact that themethylation level of different families can be regulated (anddysregulated) independently in different tissues. Interestingly, thepresent data also shows that for any member of a retroelement subfamily,the methylation level in tissues from different patients can vary withincertain bounds depending on the genomic sequence context, while in thesperm experiment, which represents a single individual, the methylationlevels for any given family converge to a distinct and strikingly narrowrange of values, characteristic of each repeat family.

vii. Analysis of Relative CpG Content Among Different Repetitive ElementSubfamilies

The formal possibility that some of the differences in DNA methylationlevels could be influenced by the CpG content of the DNA sequences beingprobed was explored. This analysis involves analyzing the count of CpGresidues in the repeats and the immediately surrounding sequences, asshown for a single repetitive element family in FIG. 12. All sequencesannotated by repeat masker as belonging to AluYb were filtered to outputonly those for which there is a probe on the microarray. From all thesesequences, the ones that are shorter than the median of all sequenceswere further excluded to focus the subsequent analysis on longer(possibly full length) elements. The alignment of 60 of those sequencesselected at random was then created using clustalw2 (1.0.11) program andstandard parameters. The output of clustalw2 was subsequently parsedusing a series of custom python and R scripts to visualize thealignment. For example, an analysis of the CpG content of all classes ofMaLR elements shows that for those elements that were probed, the CpGcontent, as well as the frequency of endonuclease recognition sites isnot noticeably different. MLT1C elements, which show much lowermethylation changes relative to MSTA elements, have almost identicalmetrics of CpG count and endonuclease sites. In the case of SVAelements, the analysis shows that the CpG content, as well as thefrequency of endonuclease recognition sites is noticeably higher for theSVA-F elements than for the SVA-B elements that were probed. Yet, theSVA-B elements, in spite of their somewhat lower frequency of potentialendonuclease cutting sites, show more dramatic differences inmethylation between normal samples and tumor samples relative to theSVA-F elements. A comparison of the CpG content of L1PA17 elements showsa higher content of CpGs and endonuclease sites within a +/−400 basewindow of the probes, as compared to L1PA4 elements, which show lowervalues for both metrics. Yet, it is the L1PA4 elements that show thegreater changes in DNA methylation. The L1HS (human-specific) subfamilyshows a somewhat higher frequency of endonuclease sites compared to theL1PA3 subfamily, and yet the L1HS methylation levels change to a lowerdegree in different tissues. Analysis of the Alu elements show that theAluY subfamilies have a higher content of CpG residues and endonucleasesites compared to the relatively older AluJ and AluS subfamilies. Whilethese differences could partially contribute to the observed smallerchanges in DNA methylation observed for the older elements, thedifferences cannot account for all observations in DNA methylationchanges. It is important to note that, using different methodology,Rodriguez et al. (2008) obtained evidence suggesting that in normalcolonic epithelia the older members of the Alu family are lessmethylated than the younger members. In this analysis, the relatedAluYd8 and AluYb9 subfamilies have almost identical metrics for CpGcontent and endonuclease sites, and yet show marked differences in theirDNA methylation changes among normal tissues, tumors, and sperm. Takentogether, these observations argue against differences in the content ofCpG dinucleotides as a trivial explanation for the observed differencesin DNA methylation levels among different families of repetitiveelements.

viii. Properties of Probes Capable of Best Distinguishing Non-TumorAdjacent Tissue from Tumor Tissue

The foregoing analysis does not help to identify events that could betumor-specific. To address this issue, each individual probe associatedwith a repetitive element was ranked on the basis of its ability todifferentiate tumors from non-tumoral adjacent tissue using a Wilcoxontest. A statistical analysis involving those probes that displayedaltered methylation was performed by calculating the probe values(ratios) in tumor samples, and the likelihood of random methylationchanges as a function of the total number of probes belonging to any onefamily of repeats. The probes were ranked based on the P-valuesgenerated by a hypergeometric t-test, as shown in Table 9. The entrieswith the most significant P-values include members of the LINE-1P, AluY,LTR, and SVA families of interspersed repeats. Among theprimate-specific L1 elements, the L1PA3, L1PA2, and L1PA4 are among themost highly enriched. Among the LTR elements, the LTR7, LTR33, and HERVelements are high on the list. AluY represents the youngest family ofAlu elements, and they rank much higher than older Alu elements. TheHERV and SVA elements are among the few retrotransposon families knownto have been extensively mobilized in the human genome after thedivergence of hominids from chimpanzees (Xing et al., 2007; Wang et al.,2005; Macfarlane and Simmonds, 2004).

The data in Tables 11A and 11B summarizes salient properties of thesubset of LINE-1 elements that were identified using the Wilcoxon test,as the best DNA methylation probe variables for distinguishing tumorsfrom non-paired non-tumoral adjacent tissue. In Table 11A, the columncorresponding to relative enrichment of a set of elements shows that thehighest value (4.757) corresponds to a subset of the L1PA4 subfamily.Members of the L1PA3 subfamily are also highly enriched among the mostsignificant probes. The column specifying the median length of theelements shows that for L1PA5 and L1PA6 there is a noticeable increasein the length of the elements corresponding to the most significantprobes (almost a 2-fold increase relative to all probed elements, in thecase of L1PA6). A longer length could be associated with a higherlikelihood of having an intact L1 promoter, as well as a higherprobability of generating a full-length LINE-1 RNA transcriptionalproduct. The table also shows enrichment of probes mapping tofull-length L1 elements (FLI-L1) and ORF2-competent L1 elements(ORF2-L1, Jurka, 1998; Penzkofer, et al., 2005). L1PA4 elements, whichare the most highly enriched among the significant probes, are unlikelyto code for functional ORF2 proteins, and thus unlikely to generatereverse transcriptase. This observation indicates that possible positiveselection in tumors for long L1 elements among the most significantprobes is not operating at the level of conservation of ORF2protein-coding function.

TABLE 11A Enrichment of significant probes in all probes associated withyoung L1P lineages. Highlighted in bold are the primate L1P lineagesthat appear in post-baboon species. The 15,587 probes are the mostsignificant probes characterized in the Table 9. Enrichment iscalculated based on all 339,314 probes in the microarray. Hypergeometrictest score is recorded as well. The two highest enrichment values andtwo highest p-values are highlighted in bold. TOTAL ALL GENOMIC PROBED15,587 Most Significant Probes median median Obs/ Hyper-geo medianLength Family N length N length Exp Obs exp pval length Selection FLI-L1145 8,047 87 6,029 4 9 2.252 6.61E−03 6,028  (1) ORF2-L1 103 8,047 916,026 4 13 3.110 7.00E−05 6,026  0 L1HS 1696 987 294 6,025 14 43 3.1847.25E−12 6,026  2 L1PA2 4666 771 727 6,024 33 115 3.444 3.56E−31 6,023 (1) L1PA3 10281 952 1070 6,031 49 226 4.598 2.19E−83 6,031  1 L1PA411462 713 540 6,130 25 118 4.757 2.80E−46 6,132  2 L1PA5 10904 623 3285,659 15 46 3.053 6.91E−12 6,115 457 L1PA6 5617 888 169 2,600 8 13 1.6752.46E−02 4,076 1,476   L1PA7 12334 768 245 1,018 11 23 2.044 4.46E−04469 (549) L1PA8 7715 394 159 328 7 20 2.738 1.44E−05 275  (54) L1PA8A2210 707 72 677 3 8 2.419 5.65E−03 499 (178) LIPA10 6962 474 146 676 7 81.193 2.30E−01 1,217 542 L1PA11 3886 511 76 601 3 5 1.432 1.36E−01 1,278678 L1PA12 2320 679 59 644 3 3 1.107 2.87E−01 372 (272) L1PA13 10722 457201 503 9 13 1.408 8.12E−02 532  29 L1PA14 3561 558 66 557 3 7 2.3091.06E−02 337 (220) L1PA15 8233 547 173 502 8 16 2.013 2.73E−03 450  (52)L1PA15-16 1201 727 32 331 1 3 2.041 5.75E−02 224 (107) L1PA16 13098 482247 489 11 22 1.939 1.15E−03 488  (1) L1PA17 4722 368 114 368 5 4 0.7646.06E−01 560 192

TABLE 11B A continuation of the table from 11A showing an increase ofL1HS promoter homology in L1P members with significantly alteredmethylation patterns. For selected families of L1PAs discussed in Table11A the issue of whether the statistically significant members (Table 9)of L1 are more homologous to a promoter region of an active i.e. intactand relatively young, full length Line1 element were addressed. Aconsensus promoter region was obtained from one of the L1HScharacterized by L1Base as full lentgth and active. To generate thistable, the alignment of the 700 bases long promoter region was performedagainst all members of each lineages and against subset of significantmembers of each of the lineages. Software BLAT and parameters designatedto result in 80% homology (- minIdentity = 80 -tileSize = 10) were used.The count of alignments per lineage was recorded in the table. The “%”columns show the percentage of all elements in the group (either allrepeats or subset of significant repeats only) for which a BLATalignment was found. Note that the percentage does not reflect onsequence conservation, but is a mere statement that an alignment usingBLAT and the specified parameters is possible for a fraction ofsequences in a group. Subsequently, a hypergeometric test was used toprovide statistical significance between the count of alignments in anentire group and only significant members of the group. 15,587 MostSignificant TOTAL ALL PROBED Probes Improvement GENOMIC promoterpromoter in count of Hyper- Family N N alignments % N alignments %alignments geo pval FLI-L1 145 87 86 98.85% 9 9 100.00% 1.15% 0.00E+00L1HS 1696 294 280 95.24% 43 43 100.00% 4.76% 0.00E+00 L1PA2 4666 727 67292.43% 115 111 96.52% 4.09% 1.53E−02 L1PA3 10281 1070 972 90.84% 226 21896.46% 5.62% 8.39E−05 L1PA4 11462 540 429 79.44% 118 107 90.68% 11.23%7.57E−05 L1PA5 10904 328 178 54.27% 46 37 80.43% 26.17% 1.62E−05 L1PA65617 169 62 36.69% 13 8 61.54% 24.85% 1.41E−02 L1PA7 12334 245 32 13.06%23 3 13.04% (0.02%) 3.25E−01 L1PA8 7715 159 8 5.03% 20 0 0.00% (5.03%)6.68E−01

An additional level of analysis, shown in the Table 11B involvedmeasurement of the level of homology of sequences near the 5′ end ofeach L1 sequence with an exemplar sequence represented by the first 700bases of an active LINE-1 element of the class FLI-L1, which contain anactive promoter. Using BLAT (Kent, 2002), those 5′-end sequences ofdifferent subclasses of L1PA elements scoring with a homology of 80% orbetter were selected. The table shows that among the L1PA elementspresent in the subset of the 15,587 most significant probes, there is amuch higher percentage of sequences with good homology matches to theactive L1 exemplar. This indicates that possible selection in tumors fordemethylated L1 elements could involve specific features of the sequenceat the 5′-end of the element, which harbor potential forward promoter aswell as antisense promoter activity (discussed in section 3.9, below).If, for any given class of elements (i.e. L1PA5), a potentially activepromoter exists, it may be more likely to be associated with afull-length L1PA5 elements. Along this line of thought, the apparentlength-selection could be a by-product of functional promoter selection.

ix. Functional Significance of the Enrichment of Demethylated Line-1Elements in Tumors

The simplest interpretation of the age-stratified dysregulation DNAmethylation of repetitive DNA observed among normal tissue, non-tumoraladjacent tissue and tumors is that the younger members of repetitive DNAfamilies are the most likely to be transcribed, and that these RNAtranscripts are best able in normal cells to trigger RNA-directedchromatin silencing. Silencing efficiency would be additionally enhancedin the younger elements due to reduced sequence divergence, as recentlyproposed by Reiss and Mager (2007). Paradoxically, for the very youngestmembers of retrotransposon families, exemplified in the data set bySVA-F and full-length, active LINE-1s, the emergence of optimalsilencing may still remain incomplete, for lack of sufficientevolutionary time for RNA-mediated silencing traits to be selected andfixed. Such a hypothesis could explain why the very youngest, humanspecific retrotransposon families are relatively under-methylated innormal tissue, as compared to their relatively older and more “mature”primate siblings. It has been reported that heterochromatic piRNA lociinteract with potentially active transposons in Drosophila resulting intransposon control (Brennecke et al., 2007). Normal transcriptionalevents involving retrotransposon sequences occur in human oocytes(Georgiu et al, 2009) and are well documented in the murine germ-line,where DNA is transiently demethylated, and where piRNAs have beenimplicated in reestablishing silencing (Aravin et al., 2007, 2008,Kuramochi-Miyagawa, 2008). Unfortunately, the general understanding ofthe evolutionary history of piRNAs remains extremely limited,particularly with regards to the mechanism responsible for generation ofnew functional piRNA sequences, as novel subclasses of retrotransposonsenter the genome.

The most recently evolved repetitive elements can have accumulated fewermutations or truncations deleterious to their function, and theirselective loss of epigenetic silencing could be associated withfunctions that increase the fitness of tumors, therefore subjecting topositive selection. An example of such a function would be thetranscriptional activation of genes with oncogenic potential as a resultof loss of methylation of cryptic promoter or enhancer sequences withina full-length retrotransposon. For example, Roman-Gomez et al (2005)reported that L1 hypomethylation led to activation of c-MET genetranscription driven by an L1 antisense promoter (Speek, 2001, Nigumannet al, 2002) located within intron one of the c-MET gene in patientswith blast crisis chronic myeloid leukemia (BC-CML), where thesetranscriptional events may contribute to disease progression. Morerecently, Lin et al. (2006) reported the induction of an abnormalchimeric transcript in esophageal adenocarcinomas, initiated from theantisense promoter located in the 5′-UTR of a full-length LINE-1element. Another function that could be subject to positive selection intumor cell lineages is the transcriptional activation of aretrotransposon ORF coding for a reverse transcriptase. It has beenreported that the reverse transcriptase inhibitor efavirenz antagonizesthe growth of H69 human small-cell lung carcinomas in nude mice(Sinibaldi-Vallebona et al., 2005). The same group has recently reportedthat inhibition of the reverse transcriptase messenger RNA of LINE-1elements or HERV-K elements leads to loss of tumorigenic potential incell lines (Oriccio et al., 2007). Of course, an important caveat isthat the reported occurrence in cancer cells of transcripts or proteinsderived from retrotransposons could be merely coincidental, not causal.

An interesting functional hypothesis regarding L1 retrotransposonsequences is the possible unselfish participation of expressed andreverse-transcribed LINE-1 elements in nonstandard DNA double strandbreak repair in the context of oncogenesis, where normal repairmechanisms are disrupted (Helleday et al., 2007). Repair ofdouble-strand breaks by gene conversion involving different endogenousLINE-1 elements has been reported in the mouse (Tremblay et al., 2000).DNA repair by endonuclease-independent LINE-1 retrotransposition wasfirst reported by Morrish et al. (2002, see commentary by Eickbush,2002) using a model reporter vector transfected into CHO cells. Thispathway was found to be dependent on reverse transcriptase activity, andresulted in integration of a truncated LINE-1 sequence lacking targetsite duplications. Recently Sen et al. (2007) characterized sites in thehuman genome where L1 elements have integrated without signs ofendonuclease-related activity, and found that the structural features ofthese loci suggested that they arose by double-strand break repair,resulting in translocations or deletions. Also relevant are the findingsof Srikanta et al (2009), who scanned the human, chimpanzee, and rhesusmacaque genomes, and reported 23 instances of Alu integration eventsmost likely mediated by endonuclease-independent DNA repair (EIDR).Observations of truncated LINE-1 insertions in the context ofphysiological stress have been reported in two mouse models, lambda-MYClymphomas and endogenous oxidative stress caused by deficient G6PDexpression. In these two models (Rockwood et al, 2004), the LINE-1insertions, plausibly generated by the EIDR mechanism, have beencaptured within a chromosomally integrated lac-Z reporter vector. Theobserved insertions represent predominantly incomplete elements, andtheir frequency (25% of all events) is higher than the frequency ofLINE-1 sequences in the mouse genome (10%).

EIDR involving LINE-1 and Alu elements could be ubiquitous in humancancer cells, and can have adaptive value, enhancing the viability ofDNA repair-deficient tumor cells. The rapid rate of progress inhigh-throughput, low cost DNA sequencing will make it possible tosequence a large number of human tumor genomes to elucidate thesequences found at sites of genomic rearrangements, insertions, anddeletions (CGP, 2009). Emerging genome analysis tools will alsofacilitate the design of experiments to assess the potential adaptivevalue of EIDR mediated by retroelements.

4. Conclusions

A novel microarray method for analysis of DNA methylation, based on theuse of methylation sensitive as well as methylation dependentendonucleases, enables the interrogation of methylation levels in allcompartments of the genome, including repetitive elements. Analysis of asubstantial set of samples of squamous carcinomas of the head and neck,as well as non-tumor adjacent tissue and normal controls, reveals acomplex framework of epigenetic dysregulation, where loss of methylationdifferentially affect distinct families of repetitive elements.Predominantly the younger, primate-specific members of retroelementfamilies suffer the most dramatic loss of methylation, with theexception of some extremely young, human-specific retroelements. Thesecomplex patterns of differential susceptibility to disruption ofsilencing are probably a result of the natural history of evolutionarydomestication of retroelements in genomes, in interplay with a minimaltime requirement for strong silencing to be established.Primate-specific subfamilies of LINE-1 elements appear to suffer aparticularly pronounced loss of methylation in tumors, with the mostdramatic changes apparently observed for those primate retroelementswith conserved promoter regions and longer sequences.

C. Example 3 Obtaining Status Biomarker Cancer Risk Score Metrics from aHuman Buccal Sample Using a Microarray-Based Assay

A buccal sample can be obtained from the cheek of a subject using the“Buccal DNA Sample Collection Kit” (Bode Technologies). The DNA can beprocessed with two sets of different restriction endonucleases(methylation sensitive, or methylation dependent), and then amplifiedwith phi29 DNA polymerase as described (Szpakowski et al, 2009).

The sample can be applied to a Nimblegen DNA microarray containing a setof DNA oligonucleotide probes, each 50 bases long, representing agenomic sampling for 25 different repetitive element families.Optionally, the probes can be 60, or 70, or 80, or 90 bases long. On theaverage each repetitive element family comprises from 30 to severalthousand unique probe sequences, designed to be complementary todifferent specific loci in the genome. Each probe is replicated 4 timesto allow for the calculation of the standard deviation of each probemeasurement. Thus, the total number of probes in a microarray sector is25×120×4=12,000. The microarray contains 24 sectors, permitting theanalysis of 24 buccal samples at once. The total number of probes in thechip is 24×12,000=288,000.

Probe sets: The probe list can be specified by 25 families, chosen froma master set of 138 repetitive element families (Table 1), which areknown to yield good classification results. The coordinates of allprobes in all 138 families is listed in Table 15.

TABLE 1 List of Top 138 classifier categories in rank order. 1. LTR54B2. MER67D 3. MER11B 4. MER6 5. ERVL 6. U1 7. MER34B 8. MER66C 9.HUERS-P3 10. LTR56 11. MLT1G1 12. THE1B-int 13. HERV9 14. MER4D 15.LTR14C 16. MLT2D 17. HERVFH21 18. THE1B 19. LTR6B 20. MLT1A1 21. LTR4622. centr 23. Charlie5 24. MLT1D-int 25. MLT2B3 26. MER50B 27. HERVK1128. MER70A 29. Charlie3 30. PABL_B 31. MER50 32. MSR1 33. AluYa5/8 34.LTR2 35. LTR10B 36. MLT1A 37. HERVK22 38. HERVL 39. GSAT 40. LTR33A 41.LTR10B1 42. MSTB-int 43. Cheshire 44. LTR17 45. LTR51 46. MSTA 47.MER11A 48. MER51B 49. MLT2B2 50. SVA 51. SVA_A 52. SVA_B 53. SVA_C 54.SVA_D 55. SVA_E 56. SVA_F 57. L1PA12 58. MSTC 59. ERVL-B4 60. LTR9B 61.HERVK14 62. LTR14B 63. HUERS-P2 64. LTR29 65. LTR6A 66. MSTB1 67.ALR/Alpha 68. MSTD 69. LTR48B 70. LTR52 71. LTR8 72. MER105 73. LTR8A74. MER67A 75. HUERS-P1 76. MER92B 77. LTR22 78. LTR7B 79. L1PB1 80.MER51A 81. L1PA15-16 82. LTR36 83. LTR28 84. PABL_A 85. LTR45B 86.MER4D1 87. AcHobo 88. LTR7Y 89. HERVL18 90. LTR48 91. LTR30 92. MLT1A093. HERVK9 94. LTR1B 95. LTR45C 96. MSTB 97. LTR47A 98. MER11D 99.LTR19A 100. THE1C 101. LTR66 102. MLT1E2 103. MER115 104. SST1 105.MER34B-int 106. LTR65 107. MER34C 108. MER44D 109. MER57A-int 110.MLT2B1 111. L1PA10 112. MER4A1 113. MER6A 114. MLT1E 115. MER41E 116.MLT2B4 117. 7SK 118. HERVP71A 119. L1MA7 120. L1PBa1 121. LTR5 122.MER44C 123. GSATII 124. THE1D 125. L1MA1 126. LTR7 127. LTR9 128. MER63A129. MER91C 130. LTR5A 131. Harlequin 132. L1PB4 133. MLT1F1 134. L1M3f135. MLT1F 136. MLT2A2 137. LTR14 138. MER11C

The microarray can be subject to a hybridization protocol, and themicroarray signals can be processed using bioinformatics protocols asdescribed by Szpakowski et al., 2009.

A Random Forest binary tree classifier can be used to process the data(Strobl et al., 2009), yielding a classification result. The classifierassigns the sample to one of the three following categories: Normal,Tumor, Non-tumor tissue-at-risk.

The list of top 138 Classifier Categories (repetitive element families)in order of rank is as follows: LTR54B, MER67D, MER11B, MER6, ERVL, U1,MER34B, MER66C, HUERS-P3, LTR56, MLT1G1, THE1B-int, HERV9, MER4D,LTR14C, MLT2D, HERVFH21, THE1B, LTR6B, MLT1A1, LTR46, centr, Charlie5,MLT1D-int, MLT2B3, MER50B, HERVK11, MER70A, Charlie3, PABL_B, MER50,MSR1, AluYa5/8, LTR2, LTR10B, MLT1A, HERVK22, HERVL, GSAT, LTR33A,LTR10B1, MSTB-int, Cheshire, LTR17, LTR51, MSTA, MER11A, MER51B, MLT2B2,SVA, SVA_A, SVA_B, SVA_C, SVA_D, SVA_E, SVA_F, L1PA12, MSTC, ERVL-B4,LTR9B, HERVK14, LTR14B, HUERS-P2, LTR29, LTR6A, MSTB1, ALR/Alpha, MSTD,LTR48B, LTR52, LTR8, MER105, LTR8A, MER67A, HUERS-P1, MER92B, LTR22,LTR7B, L1PB1, MER51A, L1PA15-16, LTR36, LTR28, PABL_A, LTR45B, MER4D1,AcHobo, LTR7Y, HERVL18, LTR48, LTR30, MLT1A0, HERVK9, LTR1B, LTR45C,MSTB, LTR47A, MER11D, LTR19A, THE1C, LTR66, MLT1E2, MER115, SST1,MER34B-int, LTR65, MER34C, MER44D, MER57A-int, MLT2B1, L1PA10, MER4A1,MER6A, MLT1E, MER41E, MLT2B4, 7SK, HERVP71A, L1MA7, L1PBa1, LTR5,MER44C, GSATII, THE1D, L1MA1, LTR7, LTR9, MER63A, MER91C, LTR5A,Harlequin, L1PB4, MLT1F1, L1M3f, MLT1F, MLT2A2, LTR14, MER11C.

D. Example 4 Obtaining Status Biomarker Risk Score Metrics from a HumanBuccal Sample Using a PCR-Based Assay

A buccal sample can be obtained from the cheek of a subject using the“Buccal DNA Sample Collection Kit” (Bode Technologies, Inc.). The DNAcan be processed with sodium bisulfite using the Zymo EZ DNAMethylation-Gold kit (Zymo Research, Inc.).

The bisulfite-modified sample can be divided into 12 aliquots and eachaliquot can be amplified by PCR using a specific pair of 12 sets ofprimers. For each primer pair, one primer can be anchored on a repeatfamily, chosen from among 138 informative families (see list in Example3). The primer can be designed by obtaining the set of DNA sequencescomprising the repeat family, and aligning the sequences with theprogram ClustalW (available at the websitech.embnet.org/software/ClustalW.html). The second primer can be anchoredon an AluY repeat consensus sequence specific for AluY elements. TheAluY consensus can be obtained by aligning a limited set of 150 randomlychosen AluY sequences with the program ClustalW.

The amplified DNA can be analyzed using a method capable of indirectlyreporting the predicted level of methylated cytosines present of at CpGdinucleotide positions prior to bisulfite treatment, which convertscytosine to uridine, but does not convert methylcytosine. A preferredmethod, due to its low cost, is electrochemical detection (ECD, Nakaharaet al., 1992) of cytosine and thymidine. The ratio of cytosine tothymidine can be converted to a relative DNA methylation level. Analternative method that can be used to obtain the ratio of cytosine tothymidine is Nanopore DNA sequencing (Clarke et al, 2009).

A Random Forest binary tree classifier can be used to process the data(Strobl et al., 2009), yielding a classification result. The classifierassigns the sample to one of the three following categories: Normal,Tumor, Non-tumor tissue-at-risk.

E. Example 5 Obtaining Status Biomarker Risk Score Metrics from a HumanBuccal Sample Using 5-methyl-C-Binding Selection and Quantitative PCR

A buccal sample can be obtained from the cheek of a subject using the“Buccal DNA Sample Collection Kit” (Bode Technologies, Inc.). The DNAcan be sheared by nebularization. It can then be immobilized using anantibody column, using an antibody capable of binding specifically 5methyl cytosine. Alternatives to using a methyl-binding antibody areusing either the MBD1 or the MECP2 methyl-binding proteins to immobilizethe methylated DNA. This step (Sorensen & Collas, 2009) removesmethylated DNA from solution, releasing an unmethylated DNA fraction.The immobilized, methylated DNA can then be recovered from themethyl-bindings column.

After 5-methyl-C-content separation, the methylated and the unmethylatedDNA samples can be divided into 12 aliquots and each aliquot isamplified by quantitative PCR (as indicated in the next paragraph) usinga specific pair of 12 sets of primers. For each primer pair, one primercan be anchored on a repeat family, chosen from among 138 informativefamilies (Table 1). The primer can be designed by obtaining the set ofDNA sequences comprising the repeat family, and aligning the sequenceswith the program ClustalW (available at the websitech.embnet.org/software/ClustalW.html). The second primer can be anchoredon an AluY repeat consensus sequence specific for AluY elements. TheAluY consensus can be obtained by aligning a limited set of 150 randomlychosen AluY sequences with the program ClustalW.

The amount of methylated and unmethylated DNA is determined usingnanoliter-microarray quantitative PCR (Morrison et al., 2006; Dixon etal., 2009). This analytical format contains 3072 individual PCR reactionfeatures, and enables the analysis of samples from 64 individuals, inquadruplicate, using specific primer pairs that measure the levels of 12different repetitive element families.

A Random Forest binary tree classifier is used to process the data(Strobl et al., 2009), yielding a classification result. The classifierassigns the sample to one of the three following categories: Normal,Tumor, Non-tumor tissue-at-risk.

F. Example 6 Obtaining Status Biomarker Risk Score Metrics and GeneticState Data from a Human Buccal Sample Using Oligonucleotide-Mediated DNACapture, Followed by DNA Sequencing Using a Pacific Biosciences SMRTSystem

A buccal sample can be obtained from the cheek of a subject using the“Buccal DNA Sample Collection Kit” (Bode Technologies, Inc.). The DNAfrom target repetitive element loci can be captured (Gnirke et al, 2009)using several long oligonucleotides (with a few degenerate basepositions) specific for a consensus DNA sequence of each of 20 differentrepetitive element families. The degenerate positions enable binding ofrepetitive DNA at positions where the consensus sequence is imperfect.In this example, the 20 families are: LTR54B, MER11B, MER34B, LTR56,THE1B, HERV9, LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D, HERVK11,LTR10B, HERVK22, MER6, MER66C, MLT1G1, MER4D, MLTD2. The repetitiveelement families used for sequence capture comprises 20 families, chosenfrom a master set of 138 repetitive element families (Table 1), whichare known to yield good classification results. The coordinates of allprobes in all 138 families is listed in Table 15.

The captured material can be released from the capture oligonucleotides,and the released DNA can be sequenced using the Pacific Biosciences SMRTsystem (Flusberg et al., 2010), which is capable of distinguishingcytosine from methylcytosine. The amount of DNA methylation can becalculated using the sequence data.

A Random Forest binary tree classifier can be used to process the data(Strobl et al., 2009), yielding a classification result. The classifierassigns the sample to one of the three following categories: Normal,Tumor, Non-tumor tissue-at-risk.

Due to the fact that the Pacific Biosciences single-molecule real-timeSMRT system is capable of producing of long sequence reads, the datagenerated in this example will contain information aboutsingle-nucleotide polymorphisms (SNPs) present in the captured DNA loci.The base present at each SNP position in the sequenced locus will bedifferent in different individuals being tested by this method. Thus, inthis example data can be generated that specifies the Genetic State forsome of the status biomarkers.

G. Example 7 Obtaining Status Biomarker Risk Score Metrics and GeneticState Data from a Human Buccal Sample Using Two Consecutive Steps ofOligonucleotide-Mediated DNA Capture, Followed by DNA Sequencing Using aPacific Biosciences SMRT System

A buccal sample can be obtained from the cheek of a subject using the“Buccal DNA Sample Collection Kit” (Bode Technologies, Inc.). The DNAfrom target repetitive element loci can be captured (Gnirke et al, 2009)using several long oligonucleotides (with a few degenerate basepositions) specific for a consensus DNA sequence of each of 20 differentrepetitive element families. The degenerate positions enable binding ofrepetitive DNA at positions where the consensus sequence is imperfect.In this example, the 20 families are: LTR54B, MER11B, MER34B, LTR56,THE1B, HERV9, LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D, HERVK11,LTR10B, HERVK22, MER6, MER66C, MLT1G1, MER4D, and MLTD2. The repetitiveelement families used for sequence capture comprises 20 families, chosenfrom a master set of 138 repetitive element families (Table 1), whichare known to yield good classification results. The coordinates of allprobes in all 138 families is listed in Table 15.

The captured material can be released, and then re-captured (Gnirke etal, 2009), using a second set of several capture oligonucleotidesspecific for a consensus sequence for AluY and another set of consensussequences for AluSx, AluSp, AluSg and AluSc repetitive elements. Thiscan result in binding of DNA containing one repetitive element from thefirst set of 20, as well as a neighboring AluY or AluSx or AluSp orAluSg or AluSc elements.

The twice-captured material can be released from the captureoligonucleotides, and the released DNA can be sequenced using thePacific Biosciences SMRT system (Flusberg et al., 2010), which iscapable of distinguishing cytosine from methylcytosine. The amount ofDNA methylation can be calculated using the sequence data.

A Random Forest binary tree classifier can be used to process the data(Strobl et al., 2009), yielding a classification result. The classifierassigns the sample to one of the three following categories: Normal,Tumor, Non-tumor tissue-at-risk.

Due to the fact that the Pacific Biosciences single-molecule real-timeSMRT system is capable of producing of long sequence reads, the datagenerated in this example will contain information aboutsingle-nucleotide polymorphisms (SNPs) present in the captured DNA loci.The base present at each SNP position in the sequenced locus will bedifferent in different individuals being tested by this method. Thus, inthis example data can be generated that specifies the Genetic State forsome of the status biomarkers.

H. Example 8

A set of DNA methylation biomarkers that are informative regarding thestability of the genome and the epigenome in tissues are disclosed. Thebiomarkers were discovered through statistical analysis of a data setgenerated by microarrays that sampled the entire human genome, andincluded probes for gene promoters, non-gene-non-repetitive probes, andrepetitive element probes.

The original set of microarray data comprised a list of 139,379variables including gene probes, unique probes and repetitive elementprobes. In order to improve the robustness of the DNA methylationmetrics, a strategy was developed whereby the probes belonging to theset of “repetitive elements” were subdivided in a total of 901categories, based on their membership in specific sub-families ofrepetitive elements. For example, the 49 probes in the microarraymapping to a MER67D repetitive element (MER67D is a member of the LTRclass of repetitive elements) were placed in one of the 901 categories,and the DNA methylation values of the 49 probes for that specificcategory were averaged. Repetitive element categories represented byless than 30 probes were not included in the set of 901 categories. Theaverage methylation value of each of the 901 categories was used toperform a 3-way classification of normal tissue, vs. tumor tissue, vs.nontumor margin tissue.

Presented herein is a detailed report on a new set of classificationexperiments, performed with a subset of variables of higher quality.Using several sets of technical replicates of microarray experiments, asubset of the 901 category variables was selected based on a definedthreshold value of the standard deviation the calculated values for eachcategory, in 3 sets of 3 technical replicates. The subset of variablewhere the coefficient of variation was no larger than 15% was thenselected. This variance quality filter reduced the number of variablesto 569 categories. Table 18 is a list of these variables (repetitive DNAsequence families; status biomarkers).

A classification experiment using a Random Forest (RF) binary decisiontree algorithm (Breiman, 2001) using the 569 repeat category variableswas performed. The error rate in this analysis was 13%mis-classification. A list of the top 75 classifier variables wasgenerated, which comprise categories of repeats according to the resultsof the RF classifier.

A classification experiment was then performed using a Support VectorMachine (SVM, Vapnik, 1998, Guyon et. al, 2002) classifier run using 569variables. A list of the top 75 classifier variables was generated,which comprise categories of repeats according to the results of the SVManalysis. The performance of the SVM classifier was tested using topvariables only, and found the best performance (100% accuracy) usingeither the top 18 or the top 19 variables.

Finally, the top 50 variables were ranked by the SVM classifier, andused in a Random Forest classification run. The error rate in this RFrun was 8.1% mis-classification. This indicates that the SVM can be moreeffective than the RF algorithm in surveying all the available 569variables to find the best classifiers among these variables.

1. Analysis of the Genomic Loci Comprising the Top Classifier Variables

The genomic organization of the repetitive elements that comprise thetop variables in the classifiers was examined. It was observed that thegenomic loci comprising the best classifiers have a structurecharacterized by the presence of two or three different repetitiveelements, co-existing within a DNA window of approximately 500 to 1000bases. A common organizational theme is a combination of an elementbelonging to the LTR family of retrotransposons, and an elementbelonging to the AluY (Young Alu) or AluSx family of retrotransposons.This information is presented in Table 14.

In the majority of cases, the LTR retrotransposon comprising a topclassifier variable belongs to a primate-specific family, implying arelatively recent evolutionary origin. A small set of highly-performingvariables consists of DNA transposons, such as Charlie3_MER1 andCharlie5_MER1, and Cheshire MER1 which have a different evolutionaryorigin. Yet another set of variables comprises repetitive sequencesbelonging to centromeric DNA, such as mini-satellite repeat 1 (MSR1),Gamma-satellite DNA, and Alpha-ALR-satellite DNA.

The presence of two or even three different repetitive element sequenceswithin a window of 500 to 1000 bases may have biological consequences,for example a tendency of these loci to undergo loss of epigeneticsilencing when cells are under stress, such as oxidative stress orcytokine-induce stress. Additionally, it is well known that centromericsequences, which comprise closely spaced DNA repeats, are subject toloss of methylation under conditions of cellular stress.

TABLE 15 List of Coordinates of Probes for Top 138 Status Biomarkers(Repetitive DNA Sequence Families) based on human genome sequence HG_16(NCBI, Build 34 (HG16), information available at websitencbi.nlm.nih.gov/mapview/stats/BuildStats.cgi?taxid=9606&build=34&ver=2; downloadable fromhgdownload.cse.ucsc.edu/goldenPath/hg16/bigZips/). Chromosome Start EndTable 15A. Repeat Category 7SK chr17 71257544 71257594 chr10 9158818091588230 chr19 38045695 38045745 chr19 60940555 60940605 chr1 2040546320405513 chr1 92963690 92963740 chr1 160297183 160297233 chr1 165128378165128428 chr20 38075670 38075720 chr20 46173367 46173417 chr22 3569407235694122 chr22 41192174 41192224 chrX 11993608 11993658 chr2 2785224927852299 chr2 47561290 47561340 chr2 61403203 61403253 chr2 7664686076646910 chr2 112856736 112856786 chr2 158357809 158357859 chr2161915873 161915923 chr2 206968141 206968191 chr3 73501367 73501417 chr3158056235 158056285 chr4 47597771 47597821 chr4 47597708 47597758 chr487716288 87716338 chr4 110995665 110995715 chr4 122441323 122441373 chr4183452025 183452075 chr5 6901137 6901187 chr5 29994535 29994585 chr5124762901 124762951 chr5 143943593 143943643 chr6 13655995 13656045 chr638161009 38161059 chr6 39555238 39555288 chr6 39555317 39555367 chr6106398279 106398329 chr7 2782798 2782848 chr7 69875282 69875332 chr8102106856 102106906 chr8 127792715 127792765 chr8 144729511 144729561chr9 128240427 128240477 chr12 10128218 10128268 chr12 42120864 42120914chr12 79239912 79239962 chr12 111117041 111117091 chr13 9529962295299672 chr13 97556227 97556277 chr13 108265516 108265566 chr1488168864 88168914 chr10 64643241 64643291 chr15 94759559 94759609 chr1661552446 61552496 chr16 67131812 67131862 chr16 81775188 81775238 chr1734360776 34360826 Table 15B. Repeat Category AcHobo chr17 3803364838033698 chr17 38344004 38344054 chr17 39149510 39149560 chr17 4261503942615089 chr17 46256291 46256341 chr17 46294369 46294419 chr17 4667981246679862 chr17 47504094 47504144 chr17 48146243 48146293 chr17 4907514049075190 chr17 49074938 49074988 chr17 49206680 49206730 chr17 5443221854432268 chr10 86898106 86898156 chr17 66782871 66782921 chr17 6804891068048960 chr17 70613320 70613370 chr10 88647234 88647284 chr17 7556752575567575 chr17 75711693 75711743 chr17 76070843 76070893 chr17 7638506176385111 chr17 76796859 76796909 chr17 77036236 77036286 chr17 7703601077036060 chr17 77982432 77982482 chr17 78525870 78525920 chr17 7852738378527433 chr17 78846446 78846496 chr17 78912489 78912539 chr17 7891237878912428 chr10 91717659 91717709 chr10 91725026 91725076 chr10 9249442992494479 chr17 79992627 79992677 chr17 80671667 80671717 chr18 36478833647933 chr18 6293746 6293796 chr18 10916207 10916257 chr18 1511389615113946 chr18 20466119 20466169 chr18 27660595 27660645 chr18 2799894427998994 chr10 96960292 96960342 chr18 43228144 43228194 chr18 4361257143612621 chr18 44541327 44541377 chr18 46566300 46566350 chr18 5398547453985524 chr18 54338110 54338160 chr18 54663374 54663424 chr18 5481934254819392 chr18 58471019 58471069 chr18 58938483 58938533 chr18 5936707059367120 chr18 62321171 62321221 chr18 67314825 67314875 chr18 7375940773759457 chr18 74511608 74511658 chr19 438082 438132 chr10 9983825499838304 chr10 99838182 99838232 chr19 1596543 1596593 chr10 101189818101189868 chr19 4085549 4085599 chr19 4595931 4595981 chr19 46811034681153 chr19 4738227 4738277 chr19 5727319 5727369 chr19 70790917079141 chr19 7135546 7135596 chr19 7606787 7606837 chr19 79178457917895 chr19 13470559 13470609 chr19 14292747 14292797 chr10 102974097102974147 chr19 16580710 16580760 chr19 16581183 16581233 chr19 1664223416642284 chr10 103595788 103595838 chr19 22559892 22559942 chr1937379860 37379910 chr19 37379641 37379691 chr19 37744604 37744654 chr1940384870 40384920 chr19 43909308 43909358 chr19 50507087 50507137 chr1950507255 50507305 chr19 55191494 55191544 chr19 55477378 55477428 chr10112439269 112439319 chr19 56503997 56504047 chr19 59791392 59791442chr10 6059521 6059571 chr19 60145473 60145523 chr19 60512126 60512176chr19 61172002 61172052 chr19 61369087 61369137 chr19 61673912 61673962chr19 61673765 61673815 chr19 62206915 62206965 chr1 1219130 1219180chr1 2222080 2222130 chr10 115289131 115289181 chr1 6424683 6424733 chr18853924 8853974 chr1 8886972 8887022 chr1 9179315 9179365 chr1 1031111510311165 chr1 10397455 10397505 chr1 10696981 10697031 chr1 1104246211042512 chr1 13900746 13900796 chr1 14530795 14530845 chr1 1738736717387417 chr1 17395065 17395115 chr1 17981043 17981093 chr1 1958460419584654 chr1 21945039 21945089 chr1 22727204 22727254 chr1 2403309424033144 chr1 24064272 24064322 chr1 26371003 26371053 chr1 3566489735664947 chr1 36098518 36098568 chr1 38810163 38810213 chr1 3912643939126489 chr1 39601783 39601833 chr1 39798956 39799006 chr1 4321220843212258 chr1 43528788 43528838 chr10 122329373 122329423 chr1 4685822546858275 chr1 50188781 50188831 chr1 53285438 53285488 chr1 5484659654846646 chr1 62160833 62160883 chr1 66577709 66577759 chr10 124286273124286323 chr1 71292743 71292793 chr1 81550129 81550179 chr10 125085398125085448 chr1 86088966 86089016 chr1 86089283 86089333 chr1 9082162390821673 chr1 94055018 94055068 chr1 109893113 109893163 chr1 111070660111070710 chr1 111070711 111070761 chr10 126161462 126161512 chr1113615663 113615713 chr1 116751098 116751148 chr10 126558072 126558122chr1 147926436 147926486 chr1 147965385 147965435 chr1 149875317149875367 chr1 149875082 149875132 chr1 153293045 153293095 chr1153351320 153351370 chr1 153416440 153416490 chr1 154089424 154089474chr1 159571798 159571848 chr1 172605308 172605358 chr1 174157811174157861 chr1 174157721 174157771 chr10 129340694 129340744 chr1180484076 180484126 chr1 184302182 184302232 chr1 198128206 198128256chr10 130052346 130052396 chr1 201953707 201953757 chr1 201953594201953644 chr1 202558286 202558336 chr10 130466232 130466282 chr1208377402 208377452 chr1 216809255 216809305 chr1 217611296 217611346chr1 224597813 224597863 chr1 225382647 225382697 chr1 227014811227014861 chr1 228032360 228032410 chr1 231333978 231334028 chr1242201154 242201204 chr1 243774736 243774786 chr1 243818801 243818851chr20 1639037 1639087 chr20 2359815 2359865 chr10 132655907 132655957chr20 4794544 4794594 chr10 132875864 132875914 chr20 8352707 8352757chr20 8785045 8785095 chr20 12744038 12744088 chr20 15219245 15219295chr20 16331983 16332033 chr20 17421547 17421597 chr20 18167373 18167423chr20 19256468 19256518 chr20 25016578 25016628 chr20 31517721 31517771chr20 33981949 33981999 chr20 35663411 35663461 chr20 44664779 44664829chr20 46788847 46788897 chr20 47731514 47731564 chr20 49171062 49171112chr20 49991611 49991661 chr20 50477256 50477306 chr20 52090981 52091031chr20 53032794 53032844 chr20 56171631 56171681 chr20 56315136 56315186chr20 58741009 58741059 chr10 134482282 134482332 chr21 1820555918205609 chr21 19124225 19124275 chr21 22237492 22237542 chr21 2227486022274910 chr11 296451 296501 chr11 356079 356129 chr21 31772150 31772200chr21 32549101 32549151 chr21 33502480 33502530 chr21 35314962 35315012chr21 35314819 35314869 chr21 39201648 39201698 chr21 40375173 40375223chr21 41654572 41654622 chr21 41654818 41654868 chr21 41951798 41951848chr21 42394531 42394581 chr21 42499339 42499389 chr21 43620913 43620963chr21 43639350 43639400 chr21 45172222 45172272 chr21 45172062 45172112chr22 16032014 16032064 chr22 16838133 16838183 chr22 16838034 16838084chr22 21248399 21248449 chr22 23891448 23891498 chr22 23950631 23950681chr22 25487588 25487638 chr22 30548668 30548718 chr11 2006284 2006334chr22 33347827 33347877 chr22 34212852 34212902 chr22 35961346 35961396chr22 36399697 36399747 chr22 36715021 36715071 chr22 37945312 37945362chr22 41814512 41814562 chr22 41890927 41890977 chr22 43686217 43686267chr22 45222376 45222426 chr22 45222121 45222171 chr22 46437500 46437550chr22 47274931 47274981 chr22 48728252 48728302 chr22 48865760 48865810chr22 48958556 48958606 chrX 3103984 3104034 chrX 5405075 5405125 chrX5734438 5734488 chrX 11555492 11555542 chrX 16080155 16080205 chrX19972661 19972711 chrX 23329497 23329547 chrX 29927182 29927232 chrX38684803 38684853 chrX 38704294 38704344 chrX 38704229 38704279 chrX44239240 44239290 chrX 50271543 50271593 chr11 8044274 8044324 chr118044169 8044219 chrX 53298965 53299015 chrX 61925053 61925103 chrX69321553 69321603 chrX 70352118 70352168 chrX 76112402 76112452 chrX94539704 94539754 chrX 95347195 95347245 chrX 98993968 98994018 chrX101735540 101735590 chrX 105786269 105786319 chrX 107833581 107833631chrX 108601103 108601153 chrX 117392119 117392169 chrX 117393347117393397 chr11 10587163 10587213 chrX 121777001 121777051 chrX128957508 128957558 chrX 132294706 132294756 chrX 143188096 143188146chrX 147321813 147321863 chrX 151545850 151545900 chrX 151545792151545842 chrX 152678366 152678416 chrX 152900238 152900288 chr2 20831962083246 chr2 2083087 2083137 chr2 3145169 3145219 chr2 8708283 8708333chr2 9363992 9364042 chr2 11844620 11844670 chr2 12877875 12877925 chr216118983 16119033 chr2 16393967 16394017 chr2 20014907 20014957 chr220719209 20719259 chr2 20719060 20719110 chr2 20769963 20770013 chr228539646 28539696 chr2 31340723 31340773 chr2 32967345 32967395 chr233072704 33072754 chr2 36725407 36725457 chr2 39407514 39407564 chr239593484 39593534 chr2 40768414 40768464 chr2 41198646 41198696 chr243007362 43007412 chr2 46853446 46853496 chr11 21730809 21730859 chr253966566 53966616 chr2 53966387 53966437 chr2 61059735 61059785 chr261902549 61902599 chr2 64108613 64108663 chr2 65942101 65942151 chr266836054 66836104 chr2 71782940 71782990 chr2 71912756 71912806 chr275913248 75913298 chr2 75914672 75914722 chr2 77900691 77900741 chr280220066 80220116 chr2 85451994 85452044 chr2 88328065 88328115 chr1128567205 28567255 chr2 98943490 98943540 chr2 100982445 100982495 chr2100982243 100982293 chr2 102305463 102305513 chr2 102405188 102405238chr2 105762941 105762991 chr2 105764544 105764594 chr2 106830104106830154 chr2 109263678 109263728 chr11 32523448 32523498 chr1011930284 11930334 chr10 11931290 11931340 chr2 122681427 122681477 chr2132067385 132067435 chr2 132938842 132938892 chr2 151600316 151600366chr2 158255464 158255514 chr11 34936132 34936182 chr2 166687797166687847 chr2 167546064 167546114 chr2 167545960 167546010 chr2169344452 169344502 chr2 177783711 177783761 chr2 180737244 180737294chr2 181333785 181333835 chr2 188943352 188943402 chr2 197051413197051463 chr2 201364123 201364173 chr2 201956362 201956412 chr2202193112 202193162 chr2 203041019 203041069 chr2 203095986 203096036chr11 40409480 40409530 chr2 206690687 206690737 chr2 207618146207618196 chr2 208866270 208866320 chr2 209227646 209227696 chr2212561548 212561598 chr2 220465513 220465563 chr2 230717019 230717069chr2 232444962 232445012 chr2 234359000 234359050 chr2 234359472234359522 chr2 235635960 235636010 chr2 240417573 240417623 chr2240638557 240638607 chr2 242278366 242278416 chr3 3802307 3802357 chr35032774 5032824 chr3 11992030 11992080 chr3 16195042 16195092 chr323890216 23890266 chr3 24005272 24005322 chr3 27086328 27086378 chr329437246 29437296 chr3 32129335 32129385 chr3 33972706 33972756 chr335786197 35786247 chr3 35786085 35786135 chr3 37712576 37712626 chr339197339 39197389 chr3 39528768 39528818 chr3 39528612 39528662 chr343073401 43073451 chr3 43072935 43072985 chr3 48714884 48714934 chr353172979 53173029 chr3 55338444 55338494 chr3 62349113 62349163 chr365768491 65768541 chr3 65793710 65793760 chr3 67581763 67581813 chr372639734 72639784 chr11 58108017 58108067 chr3 101235957 101236007 chr3101244428 101244478 chr3 101374368 101374418 chr11 59255927 59255977chr3 107914675 107914725 chr3 109297348 109297398 chr3 110201641110201691 chr3 113397077 113397127 chr3 114617897 114617947 chr3115113418 115113468 chr10 12728262 12728312 chr11 60413422 60413472chr11 60413164 60413214 chr11 60600501 60600551 chr3 128126644 128126694chr3 133026334 133026384 chr3 133399293 133399343 chr3 141768396141768446 chr3 142496080 142496130 chr3 143896380 143896430 chr3155378298 155378348 chr3 160793497 160793547 chr3 161214134 161214184chr3 172832364 172832414 chr3 173686615 173686665 chr3 186759221186759271 chr3 190263915 190263965 chr3 191615997 191616047 chr3195391268 195391318 chr3 195391474 195391524 chr3 198433839 198433889chr4 632936 632986 chr4 1512252 1512302 chr4 5629895 5629945 chr45977763 5977813 chr4 6429501 6429551 chr4 6621795 6621845 chr4 67437196743769 chr4 8743364 8743414 chr4 10302606 10302656 chr4 1149861511498665 chr4 11631193 11631243 chr4 17182682 17182732 chr4 2088514420885194 chr4 25284538 25284588 chr4 25867838 25867888 chr4 3374310733743157 chr4 35750293 35750343 chr4 37430378 37430428 chr4 3751826437518314 chr4 38687965 38688015 chr4 40585741 40585791 chr4 4642625146426301 chr4 46827049 46827099 chr4 46828432 46828482 chr4 7549760675497656 chr4 77296608 77296658 chr4 79926832 79926882 chr11 6557715965577209 chr4 86218993 86219043 chr4 98289148 98289198 chr4 104217720104217770 chr10 13514337 13514387 chr4 110762298 110762348 chr4124731975 124732025 chr11 66435761 66435811 chr4 130080378 130080428chr4 141349395 141349445 chr4 141775631 141775681 chr4 142857644142857694 chr4 147748273 147748323 chr4 154619764 154619814 chr4158890212 158890262 chr4 167213535 167213585 chr4 172984608 172984658chr4 179124771 179124821 chr4 179979455 179979505 chr4 185364069185364119 chr4 185364243 185364293 chr4 185364500 185364550 chr4185718954 185719004 chr4 185989038 185989088 chr4 185989243 185989293chr4 186894580 186894630 chr11 68303328 68303378 chr4 188362110188362160 chr4 188362485 188362535 chr4 188362567 188362617 chr1168335353 68335403 chr4 190491093 190491143 chr4 191221781 191221831 chr52320972 2321022 chr11 68915383 68915433 chr11 69591881 69591931 chr1169591678 69591728 chr11 69667991 69668041 chr5 26019454 26019504 chr531792469 31792519 chr5 50234969 50235019 chr5 53204858 53204908 chr554209024 54209074 chr5 55329670 55329720 chr5 58207802 58207852 chr559093596 59093646 chr5 60237819 60237869 chr11 70341686 70341736 chr564757319 64757369 chr5 66182604 66182654 chr5 66182420 66182470 chr572248492 72248542 chr5 72248935 72248985 chr5 76741345 76741395 chr577678295 77678345 chr5 80159780 80159830 chr5 85612020 85612070 chr596028341 96028391 chr5 96029344 96029394 chr5 108014312 108014362 chr5129714940 129714990 chr5 130712724 130712774 chr5 137757510 137757560chr5 139259670 139259720 chr5 139652667 139652717 chr5 145245185145245235 chr5 150355183 150355233 chr5 150355252 150355302 chr1173971842 73971892 chr5 157027162 157027212 chr5 157928299 157928349 chr5157978767 157978817 chr5 158248853 158248903 chr10 14723787 14723837chr5 168927991 168928041 chr5 172017491 172017541 chr5 173538983173539033 chr5 173538914 173538964 chr5 173799261 173799311 chr5174009991 174010041 chr5 174318368 174318418 chr5 177860099 177860149chr5 178204069 178204119 chr5 179910114 179910164 chr5 180600261180600311 chr6 641769 641819 chr6 1015494 1015544 chr6 2878482 2878532chr6 10680631 10680681 chr6 12115748 12115798 chr6 14163046 14163096chr6 14787740 14787790 chr6 14789978 14790028 chr6 14998714 14998764chr6 15320745 15320795 chr6 15336890 15336940 chr6 16503239 16503289chr6 18428310 18428360 chr6 18430008 18430058 chr6 18481550 18481600chr6 20238376 20238426 chr6 29030132 29030182 chr6 37008654 37008704chr6 37548665 37548715 chr6 37548554 37548604 chr6 42116756 42116806chr6 42178912 42178962 chr6 42407656 42407706 chr6 42544666 42544716chr6 48347126 48347176 chr6 48827503 48827553 chr6 49447343 49447393chr6 51786246 51786296 chr11 87838099 87838149 chr6 56963629 56963679chr6 63822591 63822641 chr6 64171815 64171865 chr6 64707417 64707467chr6 68186050 68186100 chr6 69749351 69749401 chr6 71138656 71138706chr11 91615420 91615470 chr6 83153884 83153934 chr6 107636826 107636876chr6 107637213 107637263 chr6 107755005 107755055 chr6 109045928109045978 chr11 94557072 94557122 chr6 112729491 112729541 chr6114788654 114788704 chr11 94857374 94857424 chr6 122487214 122487264chr6 123110279 123110329 chr6 127186452 127186502 chr6 128522920128522970 chr6 128804568 128804618 chr11 96788761 96788811 chr6138310191 138310241 chr6 139796646 139796696 chr6 147951537 147951587chr6 150520153 150520203 chr6 152116579 152116629 chr6 152295686152295736 chr6 158051939 158051989 chr6 158848861 158848911 chr6162180352 162180402 chr6 163530858 163530908 chr6 163530781 163530831chr6 166119506 166119556 chr6 167303587 167303637 chr11 104824327104824377 chr6 168314321 168314371 chr6 168860792 168860842 chr7 15155421515592 chr7 4279874 4279924 chr7 5049792 5049842 chr7 5056113 5056163chr10 16671458 16671508 chr10 16671317 16671367 chr7 10376052 10376102chr7 11776211 11776261 chr7 12687068 12687118 chr7 18752497 18752547chr11 111790318 111790368 chr7 35932365 35932415 chr7 38890776 38890826chr7 39524770 39524820 chr7 42964743 42964793 chr7 47277063 47277113chr7 47276843 47276893 chr7 57546257 57546307 chr7 67220930 67220980chr7 69388316 69388366 chr11 116141133 116141183 chr7 79354441 79354491chr7 87469330 87469380 chr7 96278058 96278108 chr7 96388066 96388116chr7 102124333 102124383 chr7 104032274 104032324 chr7 104032077104032127 chr7 105745327 105745377 chr7 115683646 115683696 chr7120032332 120032382 chr7 124669591 124669641 chr7 128698268 128698318chr7 132326854 132326904 chr7 146649075 146649125 chr7 147746302147746352 chr7 148913230 148913280 chr7 150355749 150355799 chr7150561164 150561214 chr11 119503110 119503160 chr7 154088238 154088288chr7 156739834 156739884 chr7 157682380 157682430 chr8 395160 395210chr8 852451 852501 chr8 1842158 1842208 chr8 1968966 1969016 chr82728861 2728911 chr8 2873020 2873070 chr8 3858119 3858169 chr8 44367714436821 chr8 8489268 8489318 chr8 9369462 9369512 chr8 9779830 9779880chr8 11150840 11150890 chr8 11397772 11397822 chr8 14354201 14354251chr8 15955420 15955470 chr8 16732596 16732646 chr8 19853889 19853939chr8 21771256 21771306 chr8 22697120 22697170 chr8 24606508 24606558chr8 26083838 26083888 chr8 26083748 26083798 chr11 123405083 123405133chr8 28498904 28498954 chr8 32218451 32218501 chr8 33275743 33275793chr8 40157204 40157254 chr11 124779706 124779756 chr8 54283716 54283766chr8 67714386 67714436 chr8 69892379 69892429 chr8 72728256 72728306chr8 75309197 75309247 chr8 78103048 78103098 chr8 79921073 79921123chr8 83011030 83011080 chr11 126454221 126454271 chr8 89786569 89786619chr11 127775200 127775250 chr8 98581455 98581505 chr8 101184624101184674 chr8 101566448 101566498 chr8 103507373 103507423 chr8104191762 104191812 chr8 105356661 105356711 chr8 105356415 105356465chr8 105964811 105964861 chr8 113101231 113101281 chr8 113494216113494266 chr8 113513869 113513919 chr8 113820262 113820312 chr8122902045 122902095 chr8 123409029 123409079 chr8 127158839 127158889chr8 132193387 132193437 chr8 133186232 133186282 chr8 139246315139246365 chr8 140909259 140909309 chr11 129855764 129855814 chr8142214170 142214220 chr11 130453419 130453469 chr9 2181442 2181492 chr92181391 2181441 chr9 3891195 3891245 chr9 3891098 3891148 chr9 41695904169640 chr9 13954069 13954119 chr9 29341931 29341981 chr9 3062981930629869 chr9 37050530 37050580 chr9 68289256 68289306 chr9 7409036174090411 chr9 74440279 74440329 chr9 77539477 77539527 chr11 133642690133642740 chr9 84246172 84246222 chr9 86380195 86380245 chr9 8664464386644693 chr9 86644557 86644607 chr11 133858765 133858815 chr9 8856729488567344 chr9 89665152 89665202 chr11 133943898 133943948 chr9 9202665692026706 chr9 93525460 93525510 chr9 93796554 93796604 chr9 9379680993796859 chr9 93797357 93797407 chr9 93823868 93823918 chr9 9384719093847240 chr9 95871806 95871856 chr9 96708262 96708312 chr9 9689636196896411 chr9 119401902 119401952 chr9 120932061 120932111 chr9122190184 122190234 chr9 122380434 122380484 chr9 125990956 125991006chr9 125992658 125992708 chr12 1914064 1914114 chr9 129190269 129190319chr9 129247319 129247369 chr12 2265067 2265117 chr9 129872736 129872786chr9 130013737 130013787 chr9 131871970 131872020 chr9 131908284131908334 chr9 132049608 132049658 chr9 132828175 132828225 chr9132829494 132829544 chr9 135389171 135389221 chr10 21769230 21769280chr12 6080881 6080931 chr12 6822395 6822445 chr12 8018497 8018547 chr1212055922 12055972 chr12 12332434 12332484 chr12 15984830 15984880 chr1221202094 21202144 chr10 24117679 24117729 chr12 25861147 25861197 chr1229833202 29833252 chr12 31495808 31495858 chr12 32077403 32077453 chr1242181489 42181539 chr10 26068046 26068096 chr12 48771175 48771225 chr1248965188 48965238 chr12 49631606 49631656 chr12 49831262 49831312 chr1251217048 51217098 chr12 51517349 51517399 chr12 53161356 53161406 chr1256376938 56376988 chr10 27865964 27866014 chr12 60730709 60730759 chr1281126768 81126818 chr10 29300672 29300722 chr12 86107433 86107483 chr1286226095 86226145 chr10 1211921 1211971 chr12 93628898 93628948 chr12102015189 102015239 chr12 103917345 103917395 chr12 106105920 106105970chr12 108018559 108018609 chr12 108591345 108591395 chr10 3068583930685889 chr12 111560024 111560074 chr12 112462044 112462094 chr12112498927 112498977 chr12 114760939 114760989 chr12 115227864 115227914chr12 118282932 118282982 chr12 118583979 118584029 chr12 119820254119820304 chr12 120049084 120049134 chr12 123246905 123246955 chr12123559989 123560039 chr12 126600641 126600691 chr12 127285303 127285353chr12 127367738 127367788 chr12 127770661 127770711 chr12 128390825128390875 chr12 130671637 130671687 chr12 131338987 131339037 chr12131653164 131653214 chr12 131653341 131653391 chr10 35498550 35498600chr13 20110580 20110630 chr13 20110509 20110559 chr13 20758061 20758111chr13 20870666 20870716 chr13 22078920 22078970 chr13 22861829 22861879chr13 23055379 23055429 chr10 36624838 36624888 chr13 25204692 25204742chr13 28523014 28523064 chr13 29949747 29949797 chr10 37156906 37156956chr13 32008367 32008417 chr13 34830722 34830772 chr13 35188419 35188469chr13 36508404 36508454 chr13 39447396 39447446 chr13 41132885 41132935chr13 41832624 41832674 chr13 43487308 43487358 chr13 48994804 48994854chr13 49686413 49686463 chr13 57145435 57145485 chr13 57146553 57146603chr13 67144550 67144600 chr13 71221036 71221086 chr13 101043270101043320 chr13 102036854 102036904 chr13 109889142 109889192 chr13110464198 110464248 chr13 111260615 111260665 chr13 111260408 111260458chr13 112766290 112766340 chr14 22748871 22748921 chr14 2306154123061591 chr10 47797856 47797906 chr14 33166741 33166791 chr14 4311492243114972 chr14 48780466 48780516 chr14 51129286 51129336 chr10 5009332350093373 chr14 61435048 61435098 chr14 61570986 61571036 chr14 6365319863653248 chr14 64305800 64305850 chr14 65920083 65920133 chr14 6890948068909530 chr10 51779035 51779085 chr14 71689608 71689658 chr14 7266728272667332 chr14 79420434 79420484 chr14 83710581 83710631 chr14 8371042383710473 chr14 86702400 86702450 chr14 89969026 89969076 chr14 9067794790677997 chr14 90677853 90677903 chr14 91758822 91758872 chr14 9382468693824736 chr10 56326610 56326660 chr14 94561222 94561272 chr14 9964402899644078 chr14 102378023 102378073 chr14 102652806 102652856 chr14102734285 102734335 chr14 103096635 103096685 chr15 20488360 20488410chr15 22718655 22718705 chr10 61977266 61977316 chr15 28911720 28911770chr15 32273533 32273583 chr15 35167266 35167316 chr15 39804196 39804246chr15 39832933 39832983 chr15 41227887 41227937 chr15 41462147 41462197chr15 47168802 47168852 chr15 48791176 48791226 chr10 64661455 64661505chr15 49992843 49992893 chr15 50183004 50183054 chr15 56196985 56197035chr15 59823806 59823856 chr15 59835984 59836034 chr15 59869013 59869063chr10 67240546 67240596 chr15 64037577 64037627 chr15 64037391 64037441chr15 71393499 71393549 chr15 71620950 71621000 chr15 72062248 72062298chr15 72992071 72992121 chr15 73183032 73183082 chr15 73810447 73810497chr15 75967763 75967813 chr15 76922818 76922868 chr15 78041941 78041991chr15 78047755 78047805 chr15 78650328 78650378 chr15 79007469 79007519chr15 82861186 82861236 chr15 86897975 86898025 chr15 87122532 87122582chr15 87806034 87806084 chr15 90641648 90641698 chr15 90937393 90937443chr15 96849263 96849313 chr15 97888048 97888098 chr15 99627216 99627266chr15 99626942 99626992 chr16 3310854 3310904 chr16 4408762 4408812chr16 4408662 4408712 chr16 5794972 5795022 chr16 12008746 12008796chr16 21094347 21094397 chr16 21527933 21527983 chr16 21553583 21553633chr16 25275696 25275746 chr16 27355940 27355990 chr16 30153978 30154028chr16 47955794 47955844 chr16 47955886 47955936 chr16 53331985 53332035chr16 57063801 57063851 chr16 57422028 57422078 chr16 59203191 59203241chr16 60719023 60719073 chr16 68864711 68864761 chr16 69335937 69335987chr10 74054424 74054474 chr16 72434844 72434894 chr16 73291357 73291407chr16 73460518 73460568 chr16 74125051 74125101 chr16 77728239 77728289chr16 78599619 78599669 chr16 81315727 81315777 chr16 81315556 81315606chr16 84058635 84058685 chr10 3319173 3319223 chr16 86205946 86205996chr16 87719830 87719880 chr16 87976536 87976586 chr16 88216477 88216527chr17 89168 89218 chr17 1690348 1690398 chr17 2824825 2824875 chr173139463 3139513 chr17 3634038 3634088 chr17 3974531 3974581 chr174632158 4632208 chr17 5557942 5557992 chr17 9842486 9842536 chr179950959 9951009 chr17 10074695 10074745 chr17 28278019 28278069 chr1730393270 30393320 chr10 81563691 81563741 Table 15C. Repeat CategoryALR/Alpha chr19 24288185 24288235 chr20 26253566 26253616 chrX 5738783557387885 chrX 60603335 60603385 chrX 60681504 60681554 chrY 97474779747527 chr2 133188017 133188067 chr2 133191550 133191600 chr2 133199583133199633 chr11 48736956 48737006 chr11 48841206 48841256 chr11 5127625751276307 chr11 54695291 54695341 chr3 90273606 90273656 chr3 9030402590304075 chr3 90358338 90358388 chr3 126704530 126704580 chr4 81134718113521 chr4 8537174 8537224 chr5 46209983 46210033 chr5 4625180046251850 chr5 46427072 46427122 chr5 49502167 49502217 chr7 6173060361730653 chr8 43561357 43561407 chr8 46987008 46987058 chr8 4739900447399054 chr9 62804300 62804350 chr9 62814866 62814916 chr9 6306139463061444 chr12 34717568 34717618 chr12 36346642 36346692 chr12 3646469736464747 chr12 36496322 36496372 chr12 36563428 36563478 chr12 3657025236570302 chr13 21796347 21796397 chr16 35128111 35128161 chr16 3513300135133051 chr17 25661821 25661871 Table 15D. Repeat Category AluYa5/8chr19 46698982 46699032 chr19 55111494 55111544 chr1 170807816 170807866chr1 229139468 229139518 chrX 150808162 150808212 chrY 8369826 8369876chr2 15663196 15663246 chr2 19652981 19653031 chr2 20137243 20137293chr2 40308786 40308836 chr2 119001256 119001306 chr2 138549806 138549856chr2 192761922 192761972 chr3 12544180 12544230 chr3 41109763 41109813chr3 85146169 85146219 chr11 60702157 60702207 chr11 60702243 60702293chr3 160240573 160240623 chr4 33841855 33841905 chr5 148430151 148430201chr6 29440752 29440802 chr6 100063559 100063609 chr11 93925178 93925228chr6 110791169 110791219 chr6 152132203 152132253 chr11 112648006112648056 chr8 12779638 12779688 chr8 92357226 92357276 chr9 1421551514215565 chr16 59082167 59082217 chr16 84662577 84662627 chr16 8906052289060572 Table 15E. Repeat Category centr chr18 11179136 11179186 chr1924288185 24288235 chr19 32817810 32817860 chr19 32829565 32829615 chr1932833169 32833219 chr19 32857592 32857642 chr19 41439574 41439624 chr1941442157 41442207 chr19 41450941 41450991 chr19 41454843 41454893 chr1942190779 42190829 chr19 42192956 42193006 chr19 42195250 42195300 chr1942197755 42197805 chr19 42238521 42238571 chr19 42240257 42240307 chr1942241761 42241811 chr19 42243830 42243880 chr19 42452388 42452438 chr1942464712 42464762 chr19 42467493 42467543 chr19 42487646 42487696 chr1942732769 42732819 chr19 42734420 42734470 chr19 42734152 42734202 chr1140839821 140839871 chr1 140841172 140841222 chr1 140842296 140842346chr1 225694342 225694392 chr20 25829405 25829455 chr20 25832323 25832373chr20 25834137 25834187 chr20 25834860 25834910 chr20 25836178 25836228chr20 25837963 25838013 chr20 25839822 25839872 chr20 25841510 25841560chr20 25843969 25844019 chr20 25960261 25960311 chr20 25961445 25961495chr20 25962189 25962239 chr20 25962783 25962833 chr20 25963950 25964000chr20 25965913 25965963 chr20 25967555 25967605 chr20 26227263 26227313chr20 26253566 26253616 chr20 29411493 29411543 chr20 29413930 29413980chr20 29414479 29414529 chr20 29416037 29416087 chr20 29465353 29465403chr21 14367127 14367177 chr22 14476328 14476378 chr22 14476980 14477030chr22 14477878 14477928 chr22 14478232 14478282 chr22 15603677 15603727chrX 57091205 57091255 chrX 57249652 57249702 chrX 57252055 57252105chrX 57253098 57253148 chrX 57255768 57255818 chrX 57258572 57258622chrX 57387835 57387885 chrX 60603335 60603385 chrX 60681504 60681554chrX 139840254 139840304 chrY 8244873 8244923 chrY 8586928 8586978 chrY8594455 8594505 chrY 8599812 8599862 chrY 8802608 8802658 chrY 88329668833016 chrY 9747477 9747527 chrY 22603191 22603241 chrY 2260488822604938 chrY 22612413 22612463 chrY 22811477 22811527 chrY 2281660522816655 chrY 22816405 22816455 chr2 31403726 31403776 chr2 132723394132723444 chr2 133188017 133188067 chr2 133191550 133191600 chr2133199583 133199633 chr11 48736956 48737006 chr11 48841206 48841256chr11 51276257 51276307 chr11 54695291 54695341 chr3 90273606 90273656chr3 90304025 90304075 chr3 90358338 90358388 chr3 126704530 126704580chr3 174852694 174852744 chr4 7062858 7062908 chr4 8113471 8113521 chr48537174 8537224 chr4 49434782 49434832 chr4 49435470 49435520 chr4133105673 133105723 chr4 133108807 133108857 chr4 133114432 133114482chr4 133119447 133119497 chr4 133121931 133121981 chr4 133128547133128597 chr4 133144611 133144661 chr4 133356425 133356475 chr546209983 46210033 chr5 46251800 46251850 chr5 46427072 46427122 chr549502167 49502217 chr5 177837223 177837273 chr6 2582761 2582811 chr62584919 2584969 chr6 2584618 2584668 chr7 57323292 57323342 chr757484576 57484626 chr7 57489252 57489302 chr7 57491668 57491718 chr757493544 57493594 chr7 57608476 57608526 chr7 57611298 57611348 chr757612957 57613007 chr7 57614872 57614922 chr7 57657592 57657642 chr757658603 57658653 chr7 57660994 57661044 chr7 61730603 61730653 chr763740873 63740923 chr7 63742146 63742196 chr7 63742406 63742456 chr763743064 63743114 chr7 63745004 63745054 chr7 63747477 63747527 chr763750110 63750160 chr7 63752506 63752556 chr7 63755151 63755201 chr763754991 63755041 chr7 63756844 63756894 chr8 43417880 43417930 chr843418739 43418789 chr8 43420187 43420237 chr8 43421368 43421418 chr843423341 43423391 chr8 43436146 43436196 chr8 43561357 43561407 chr846947006 46947056 chr8 46987008 46987058 chr8 47032918 47032968 chr847039361 47039411 chr8 47042168 47042218 chr8 47057029 47057079 chr847063194 47063244 chr8 47065152 47065202 chr8 47069102 47069152 chr847070617 47070667 chr8 47074813 47074863 chr8 47105806 47105856 chr847110603 47110653 chr8 47121169 47121219 chr8 47122261 47122311 chr847126219 47126269 chr8 47129687 47129737 chr8 47131011 47131061 chr847136244 47136294 chr8 47142204 47142254 chr8 47144188 47144238 chr847145885 47145935 chr8 47147133 47147183 chr8 47148295 47148345 chr847157918 47157968 chr8 47159194 47159244 chr8 47162521 47162571 chr847163587 47163637 chr8 47164854 47164904 chr8 47168722 47168772 chr847171751 47171801 chr8 47172827 47172877 chr8 47177504 47177554 chr847178335 47178385 chr8 47183041 47183091 chr8 47189273 47189323 chr847189098 47189148 chr8 47191211 47191261 chr8 47204227 47204277 chr847307555 47307605 chr8 47335857 47335907 chr8 47340466 47340516 chr847344331 47344381 chr8 47352798 47352848 chr8 47359859 47359909 chr847361658 47361708 chr8 47365194 47365244 chr8 47366498 47366548 chr847375191 47375241 chr8 47399004 47399054 chr9 42227834 42227884 chr942278036 42278086 chr9 42279994 42280044 chr9 42281227 42281277 chr942282424 42282474 chr9 42283864 42283914 chr9 42285059 42285109 chr942286324 42286374 chr9 43172902 43172952 chr9 43174537 43174587 chr943176252 43176302 chr9 43656896 43656946 chr9 62804300 62804350 chr962814866 62814916 chr9 63061394 63061444 chr9 63427466 63427516 chr963959998 63960048 chr9 64968296 64968346 chr9 64971276 64971326 chr1234255417 34255467 chr12 34333749 34333799 chr12 34335653 34335703 chr1234337071 34337121 chr12 34340101 34340151 chr12 34344148 34344198 chr1234346821 34346871 chr12 34348414 34348464 chr12 34349452 34349502 chr1234351406 34351456 chr12 34355131 34355181 chr12 34356000 34356050 chr1234357433 34357483 chr12 34361478 34361528 chr12 34365891 34365941 chr1234368023 34368073 chr12 34370145 34370195 chr12 34371879 34371929 chr1234373142 34373192 chr12 34375854 34375904 chr12 34376598 34376648 chr1234381192 34381242 chr12 34384507 34384557 chr12 34386405 34386455 chr1234388750 34388800 chr12 34391121 34391171 chr12 34397175 34397225 chr1234398620 34398670 chr12 34400674 34400724 chr12 34402377 34402427 chr1234403978 34404028 chr12 34407067 34407117 chr12 34410197 34410247 chr1234411525 34411575 chr12 34413190 34413240 chr12 34415055 34415105 chr1234415954 34416004 chr12 34418034 34418084 chr12 34420630 34420680 chr1234421456 34421506 chr12 34422708 34422758 chr12 34423824 34423874 chr1234425483 34425533 chr12 34427806 34427856 chr12 34429072 34429122 chr1234436147 34436197 chr12 34437394 34437444 chr12 34442947 34442997 chr1234446019 34446069 chr12 34447767 34447817 chr12 34642395 34642445 chr1234644020 34644070 chr12 34645336 34645386 chr12 34646060 34646110 chr1234648711 34648761 chr12 34649045 34649095 chr12 34650600 34650650 chr1234717568 34717618 chr12 36221876 36221926 chr12 36223975 36224025 chr1236226413 36226463 chr12 36227743 36227793 chr12 36346642 36346692 chr1236464697 36464747 chr12 36496322 36496372 chr12 36563428 36563478 chr1236570252 36570302 chr12 36832980 36833030 chr12 36835270 36835320 chr1236837781 36837831 chr12 36838599 36838649 chr12 36840393 36840443 chr1317317122 17317172 chr13 21796347 21796397 chr16 35128111 35128161 chr1635133001 35133051 chr16 35295200 35295250 chr16 35456280 35456330 chr1635458498 35458548 chr16 36108845 36108895 chr16 36111212 36111262 chr173875990 3876040 chr17 21639309 21639359 chr17 21639450 21639500 chr1721971245 21971295 chr17 21971093 21971143 chr17 21973380 21973430 chr1721975111 21975161 chr17 21976921 21976971 chr17 22047600 22047650 chr1722049889 22049939 chr17 22051925 22051975 chr17 22053384 22053434 chr1722054809 22054859 chr17 22056570 22056620 chr17 22337670 22337720 chr1725628588 25628638 chr17 25631116 25631166 chr17 25661821 25661871 Table15F. Repeat Category Charlie3 chr18 58908877 58908927 chr19 79202627920312 chr19 13997832 13997882 chr1 207583145 207583195 chr1 226034555226034605 chr21 37679077 37679127 chr22 43620446 43620496 chr22 4362365143623701 chrX 152657818 152657868 chr11 17873993 17874043 chr2 4195901841959068 chr2 95512906 95512956 chr2 97646535 97646585 chr2 135510711135510761 chr2 166219397 166219447 chr2 239580686 239580736 chr1146193204 46193254 chr3 126562363 126562413 chr11 61176671 61176721 chr3159673119 159673169 chr4 75451244 75451294 chr4 83770076 83770126 chr4124198946 124198996 chr5 480729 480779 chr5 4784010 4784060 chr5 69254736925523 chr5 25338550 25338600 chr5 27217373 27217423 chr5 8797986087979910 chr10 14252993 14253043 chr5 149177590 149177640 chr6 1319888613198936 chr6 65420348 65420398 chr6 151169241 151169291 chr6 165807070165807120 chr6 165807440 165807490 chr6 165807729 165807779 chr6165808686 165808736 chr6 165809204 165809254 chr6 166444880 166444930chr6 166448032 166448082 chr11 108417617 108417667 chr7 4736450 4736500chr7 15918159 15918209 chr7 83415113 83415163 chr8 8142313 8142363 chr8143922985 143923035 chr9 1657487 1657537 chr9 7852861 7852911 chr1288429056 88429106 chr12 103268256 103268306 chr14 65106140 65106190chr15 58372278 58372328 chr16 55484499 55484549 chr16 56739477 56739527chr16 57946441 57946491 chr16 87357200 87357250 Table 15G. RepeatCategory Charlie5 chr17 40876783 40876833 chr17 58177286 58177336 chr1763015535 63015585 chr17 66071272 66071322 chr17 75033585 75033635 chr1775595937 75595987 chr17 77023398 77023448 chr17 77023196 77023246 chr187150535 7150585 chr18 7454774 7454824 chr18 42954636 42954686 chr1098823723 98823773 chr18 75438140 75438190 chr19 974755 974805 chr191341419 1341469 chr19 4070800 4070850 chr19 5696174 5696224 chr199005140 9005190 chr19 9298032 9298082 chr19 9933526 9933576 chr1913161646 13161696 chr19 14076728 14076778 chr19 14500440 14500490 chr10103332745 103332795 chr19 35269831 35269881 chr19 41985506 41985556chr10 104831543 104831593 chr19 45404999 45405049 chr19 4889492648894976 chr19 52274575 52274625 chr19 52274818 52274868 chr19 5329631353296363 chr19 53351208 53351258 chr19 54678826 54678876 chr19 5654300856543058 chr19 56918269 56918319 chr19 56918103 56918153 chr19 5699035956990409 chr19 60471294 60471344 chr1 1701418 1701468 chr10 116022227116022277 chr1 11877501 11877551 chr1 16091477 16091527 chr1 3265979532659845 chr1 37504564 37504614 chr10 123357697 123357747 chr1 6390175063901800 chr1 63903549 63903599 chr1 75971738 75971788 chr1 7597158275971632 chr1 106030164 106030214 chr1 113694570 113694620 chr1157371606 157371656 chr1 158769859 158769909 chr10 128663547 128663597chr1 168473090 168473140 chr1 178228364 178228414 chr1 179229739179229789 chr1 181150320 181150370 chr1 195011566 195011616 chr1205138390 205138440 chr1 210529927 210529977 chr1 229920796 229920846chr1 232035771 232035821 chr1 244118283 244118333 chr1 244188960244189010 chr1 244189592 244189642 chr1 245302959 245303009 chr1245304283 245304333 chr20 10057789 10057839 chr20 19992867 19992917chr20 20305584 20305634 chr20 22418314 22418364 chr20 32043191 32043241chr20 43685997 43686047 chr20 51331092 51331142 chr20 57341955 57342005chr20 58051857 58051907 chr20 61836318 61836368 chr20 62779058 62779108chr21 33587691 33587741 chr21 33857170 33857220 chr21 43020296 43020346chr21 44202459 44202509 chr22 31806060 31806110 chr22 37293451 37293501chr22 38825374 38825424 chrX 8991717 8991767 chrX 12811361 12811411 chrX19376905 19376955 chrX 30213598 30213648 chrX 46443277 46443327 chrX61272251 61272301 chr2 5098616 5098666 chr2 9374736 9374786 chr220480446 20480496 chr2 34046124 34046174 chr2 42735645 42735695 chr2113341496 113341546 chr2 119974817 119974867 chr2 179175503 179175553chr2 179296325 179296375 chr2 206942590 206942640 chr2 221552542221552592 chr11 46128612 46128662 chr2 242872942 242872992 chr3 96821319682181 chr3 15899609 15899659 chr3 23681342 23681392 chr3 3276089632760946 chr3 38322097 38322147 chr3 47274267 47274317 chr3 5955370859553758 chr3 61675275 61675325 chr3 70655463 70655513 chr3 9669548796695537 chr3 129047683 129047733 chr4 2339095 2339145 chr4 29766122976662 chr4 25058244 25058294 chr4 37755268 37755318 chr4 3962997539630025 chr4 78398025 78398075 chr4 95830643 95830693 chr4 109983158109983208 chr4 109986196 109986246 chr4 171353331 171353381 chr4186989204 186989254 chr4 186989358 186989408 chr5 1338823 1338873 chr56803102 6803152 chr5 11895748 11895798 chr5 35231519 35231569 chr535231411 35231461 chr5 61747211 61747261 chr11 70677655 70677705 chr5112013103 112013153 chr5 116285889 116285939 chr5 141004505 141004555chr5 170999066 170999116 chr5 170998900 170998950 chr5 176983578176983628 chr5 179070738 179070788 chr5 179100313 179100363 chr5179101017 179101067 chr6 27218344 27218394 chr6 34434503 34434553 chr642547789 42547839 chr6 47763286 47763336 chr6 47765624 47765674 chr653230603 53230653 chr6 56971248 56971298 chr6 57636880 57636930 chr1190365723 90365773 chr6 107319257 107319307 chr6 109830171 109830221 chr6150864813 150864863 chr6 152334351 152334401 chr6 168133865 168133915chr6 168134180 168134230 chr7 1065164 1065214 chr7 1070106 1070156 chr71099167 1099217 chr7 2269189 2269239 chr7 5360397 5360447 chr7 63690766369126 chr7 6368935 6368985 chr7 24786849 24786899 chr11 113158586113158636 chr7 72511889 72511939 chr11 116353621 116353671 chr7 8581518585815235 chr11 117360884 117360934 chr7 154374651 154374701 chr828960483 28960533 chr8 40967944 40967994 chr8 95408477 95408527 chr898652616 98652666 chr8 144526899 144526949 chr9 67110222 67110272 chr972670216 72670266 chr9 74554257 74554307 chr9 87558359 87558409 chr990202117 90202167 chr9 93087507 93087557 chr9 96128491 96128541 chr9110093480 110093530 chr9 121551889 121551939 chr12 2781765 2781815 chr122781843 2781893 chr9 135151101 135151151 chr9 135151024 135151074 chr123347814 3347864 chr10 22284746 22284796 chr12 7985836 7985886 chr101124969 1125019 chr12 60621418 60621468 chr12 93634965 93635015 chr1294366509 94366559 chr10 30009840 30009890 chr10 30011488 30011538 chr12105339709 105339759 chr10 30967088 30967138 chr12 112148798 112148848chr10 32093904 32093954 chr12 120341567 120341617 chr12 123566612123566662 chr12 123856981 123857031 chr12 128982028 128982078 chr12129496898 129496948 chr12 130915804 130915854 chr12 131392043 131392093chr12 131526761 131526811 chr13 18066515 18066565 chr13 4139637041396420 chr13 63298021 63298071 chr13 73619515 73619565 chr10 4320828643208336 chr13 110568257 110568307 chr13 111059618 111059668 chr1421927814 21927864 chr14 22682492 22682542 chr14 56870264 56870314 chr1467658335 67658385 chr14 77582438 77582488 chr14 77588567 77588617 chr1053750480 53750530 chr15 20515997 20516047 chr15 20515844 20515894 chr1064031986 64032036 chr15 42430182 42430232 chr15 42666358 42666408 chr1548366584 48366634 chr15 56874744 56874794 chr15 61329848 61329898 chr1564522138 64522188 chr15 67482100 67482150 chr15 71546171 71546221 chr1069227420 69227470 chr10 69227592 69227642 chr10 69228407 69228457 chr1587498449 87498499 chr15 90249504 90249554 chr15 91481977 91482027 chr1591481560 91481610 chr16 1016123 1016173 chr16 1435160 1435210 chr103072381 3072431 chr16 17453812 17453862 chr16 21143401 21143451 chr1624626465 24626515 chr16 29689378 29689428 chr16 51813218 51813268 chr1675011723 75011773 chr16 87250716 87250766 chr10 75279354 75279404 chr174612399 4612449 chr17 10818486 10818536 chr17 21290770 21290820 chr1726386919 26386969 chr17 30826213 30826263 Table 15H. Repeat CategoryCheshire chr10 81773010 81773060 chr17 74394540 74394590 chr17 7439808074398130 chr18 11712490 11712540 chr1 10618225 10618275 chr1 8881656788816617 chr1 88818538 88818588 chr1 190423949 190423999 chr1 225761246225761296 chr20 51228228 51228278 chr22 17998917 17998967 chr22 1799881017998860 chr22 19586488 19586538 chrX 72684888 72684938 chrX 113389993113390043 chr2 28964171 28964221 chr11 23114011 23114061 chr2 109071884109071934 chr2 122577295 122577345 chr2 172183233 172183283 chr2172183143 172183193 chr3 50749233 50749283 chr3 87061966 87062016 chr387068970 87069020 chr3 102750524 102750574 chr3 102750585 102750635 chr4129426576 129426626 chr4 129428464 129428514 chr4 152608732 152608782chr5 139351517 139351567 chr6 20915720 20915770 chr6 33485369 33485419chr6 56888105 56888155 chr6 99364715 99364765 chr6 99364581 99364631chr7 20492031 20492081 chr7 20494483 20494533 chr7 80836915 80836965chr7 105837011 105837061 chr7 133710595 133710645 chr8 2391172 2391222chr8 6190827 6190877 chr8 17096057 17096107 chr8 17095816 17095866 chr8145790841 145790891 chr8 145793097 145793147 chr9 33834702 33834752 chr933836330 33836380 chr9 35114287 35114337 chr9 88187250 88187300 chr9135746796 135746846 chr9 135757128 135757178 chr12 43169291 43169341chr13 18467805 18467855 chr13 18467478 18467528 chr10 35545179 35545229chr10 35547095 35547145 chr10 45423258 45423308 chr14 24983410 24983460chr14 59429196 59429246 chr14 65127347 65127397 chr14 103871137103871187 chr15 43363263 43363313 chr16 67925483 67925533 chr10 7540608975406139 chr17 6912483 6912533 Table 15I. Repeat Category ERVL chr1739094931 39094981 chr17 39369869 39369919 chr17 39516492 39516542 chr1739516321 39516371 chr17 39759047 39759097 chr17 40282366 40282416 chr1740633403 40633453 chr17 41664501 41664551 chr10 81979509 81979559 chr1741916256 41916306 chr17 42159421 42159471 chr17 42324152 42324202 chr1742525744 42525794 chr17 42575356 42575406 chr17 42576034 42576084 chr1742847498 42847548 chr17 42852159 42852209 chr17 42892627 42892677 chr1742940446 42940496 chr17 42940779 42940829 chr10 82175552 82175602 chr1743505918 43505968 chr17 43596128 43596178 chr17 43941931 43941981 chr1744145331 44145381 chr17 44184415 44184465 chr17 44184897 44184947 chr1746176066 46176116 chr17 47210829 47210879 chr17 47213443 47213493 chr1747215152 47215202 chr10 83657121 83657171 chr17 47641123 47641173 chr1747825644 47825694 chr17 47826731 47826781 chr17 47828106 47828156 chr1747829837 47829887 chr17 47831363 47831413 chr17 48871203 48871253 chr1749028352 49028402 chr17 49029549 49029599 chr17 49429152 49429202 chr1749841124 49841174 chr17 49888862 49888912 chr17 50432924 50432974 chr1751513647 51513697 chr17 51756645 51756695 chr17 53176089 53176139 chr1753720827 53720877 chr17 53879889 53879939 chr17 53879692 53879742 chr1754435998 54436048 chr17 55559659 55559709 chr17 55563965 55564015 chr1085805403 85805453 chr17 57266734 57266784 chr10 85805945 85805995 chr1758021035 58021085 chr17 58056575 58056625 chr10 85978216 85978266 chr1085989986 85990036 chr17 59112058 59112108 chr17 59371761 59371811 chr1760734758 60734808 chr17 60736715 60736765 chr17 61446962 61447012 chr1761506008 61506058 chr17 61775297 61775347 chr10 86898106 86898156 chr1762723221 62723271 chr17 63264844 63264894 chr17 63774960 63775010 chr1764006055 64006105 chr17 64813207 64813257 chr17 65872706 65872756 chr1087981819 87981869 chr17 66557546 66557596 chr17 66575703 66575753 chr1767161361 67161411 chr17 67353834 67353884 chr17 67399645 67399695 chr1768455881 68455931 chr17 70735858 70735908 chr17 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23816087 23816137 chr15 24614617 24614667 chr10 6146743861467488 chr15 25477788 25477838 chr15 26142158 26142208 chr15 2616314126163191 chr15 27033848 27033898 chr15 27038405 27038455 chr15 2704227927042329 chr15 27993763 27993813 chr15 28779327 28779377 chr15 2887769328877743 chr10 62347092 62347142 chr15 29249491 29249541 chr15 2926591229265962 chr15 29457989 29458039 chr15 29642050 29642100 chr15 3016132730161377 chr15 31169853 31169903 chr10 62763732 62763782 chr10 6282557662825626 chr15 32033447 32033497 chr10 62960391 62960441 chr15 3247191932471969 chr15 32696064 32696114 chr15 33008859 33008909 chr15 3307959033079640 chr10 63035118 63035168 chr15 34073076 34073126 chr15 3447967834479728 chr15 36016013 36016063 chr15 36556125 36556175 chr15 3655598836556038 chr15 36790865 36790915 chr15 37458973 37459023 chr15 3755296237553012 chr15 37820735 37820785 chr15 38576589 38576639 chr15 3881430938814359 chr15 40000706 40000756 chr15 40799646 40799696 chr10 6423444764234497 chr15 41946204 41946254 chr15 42291112 42291162 chr15 4280831842808368 chr15 42942890 42942940 chr15 43621850 43621900 chr15 4362593143625981 chr15 43628251 43628301 chr15 43630901 43630951 chr15 4377796143778011 chr15 43795697 43795747 chr15 43973399 43973449 chr15 4960922049609270 chr15 50108731 50108781 chr15 50140667 50140717 chr15 5014059150140641 chr15 50545311 50545361 chr15 51492229 51492279 chr15 5170583951705889 chr15 51782046 51782096 chr15 51919168 51919218 chr15 5191890851918958 chr15 52102159 52102209 chr15 52102068 52102118 chr15 5215531552155365 chr15 53099777 53099827 chr10 64890222 64890272 chr15 5375866453758714 chr15 53798580 53798630 chr15 54460645 54460695 chr15 5482371454823764 chr15 54904827 54904877 chr15 55739245 55739295 chr15 5612210956122159 chr15 56256921 56256971 chr15 57258578 57258628 chr15 5753903157539081 chr15 57744246 57744296 chr10 65702323 65702373 chr15 5979189359791943 chr15 60113665 60113715 chr15 60331970 60332020 chr15 6038945160389501 chr15 61170987 61171037 chr15 61459240 61459290 chr10 6665996866660018 chr10 66866256 66866306 chr15 62393346 62393396 chr15 6352784363527893 chr15 63529569 63529619 chr15 63780368 63780418 chr15 6378018963780239 chr15 64121705 64121755 chr15 64131222 64131272 chr15 6418023664180286 chr15 64248573 64248623 chr15 64610784 64610834 chr15 6498497364985023 chr15 65997074 65997124 chr15 66775281 66775331 chr15 6685213666852186 chr15 66888512 66888562 chr15 67319348 67319398 chr15 6735827967358329 chr15 67521201 67521251 chr15 67654822 67654872 chr15 6818887768188927 chr15 68279076 68279126 chr15 68487959 68488009 chr15 6858852668588576 chr15 68794058 68794108 chr10 68904275 68904325 chr15 7071125270711302 chr10 68904619 68904669 chr10 68904940 68904990 chr15 7118244371182493 chr15 71431457 71431507 chr15 72503511 72503561 chr15 7250813072508180 chr15 72747760 72747810 chr15 72988902 72988952 chr15 7316452173164571 chr15 74920261 74920311 chr15 74923232 74923282 chr15 7492479874924848 chr15 75051622 75051672 chr15 75083503 75083553 chr15 7635646276356512 chr15 76411484 76411534 chr15 76713900 76713950 chr15 7691399876914048 chr15 77699950 77700000 chr15 78247288 78247338 chr15 7944490979444959 chr15 79601814 79601864 chr15 81185080 81185130 chr15 8171432881714378 chr15 82975774 82975824 chr15 83011349 83011399 chr15 8337628283376332 chr15 84034495 84034545 chr15 84284241 84284291 chr15 8572110885721158 chr15 86677848 86677898 chr15 86703659 86703709 chr15 8670974386709793 chr15 87273698 87273748 chr15 88193687 88193737 chr15 8878327688783326 chr15 88932073 88932123 chr15 88969803 88969853 chr15 9041699990417049 chr15 90551776 90551826 chr15 91370024 91370074 chr15 9173744891737498 chr15 92182700 92182750 chr15 92194416 92194466 chr15 9230683192306881 chr15 92849863 92849913 chr15 93353352 93353402 chr15 9402220394022253 chr15 94336774 94336824 chr15 95099680 95099730 chr15 9579565195795701 chr15 96500530 96500580 chr15 96696009 96696059 chr15 9676682896766878 chr10 69957663 69957713 chr10 69957940 69957990 chr15 9824153498241584 chr15 98571503 98571553 chr15 99542284 99542334 chr15 9968355099683600 chr15 99750086 99750136 chr10 70147677 70147727 chr16 484716484766 chr10 70213357 70213407 chr10 70217354 70217404 chr16 726160726210 chr16 751222 751272 chr16 751040 751090 chr16 750937 750987 chr16799691 799741 chr16 896450 896500 chr16 1894057 1894107 chr16 19254731925523 chr16 2196567 2196617 chr16 2786249 2786299 chr16 29935672993617 chr16 3093650 3093700 chr16 3180386 3180436 chr16 32051983205248 chr16 3223948 3223998 chr16 3248889 3248939 chr10 30154193015469 chr16 3560809 3560859 chr10 3017138 3017188 chr16 39406513940701 chr10 3024852 3024902 chr16 5143793 5143843 chr16 51799115179961 chr16 5529636 5529686 chr16 6049830 6049880 chr16 69940716994121 chr16 10279716 10279766 chr16 10300759 10300809 chr16 1033911810339168 chr16 10437615 10437665 chr16 11247497 11247547 chr16 1153101811531068 chr16 11596241 11596291 chr16 11697535 11697585 chr16 1201770612017756 chr16 12114668 12114718 chr16 12221655 12221705 chr16 1222146812221518 chr16 12222473 12222523 chr16 12862584 12862634 chr16 1349459213494642 chr16 14285640 14285690 chr16 16906758 16906808 chr16 1803288518032935 chr16 18044193 18044243 chr16 18101507 18101557 chr16 1825983118259881 chr16 19166714 19166764 chr16 19257212 19257262 chr16 1925893719258987 chr16 19805588 19805638 chr16 19969528 19969578 chr16 2024121220241262 chr16 20720540 20720590 chr16 20721230 20721280 chr16 2090075620900806 chr10 71757549 71757599 chr16 22025403 22025453 chr16 2365225923652309 chr16 23652053 23652103 chr16 23721734 23721784 chr16 2398059823980648 chr16 24017450 24017500 chr16 24492894 24492944 chr16 2464097124641021 chr16 25043347 25043397 chr16 25044777 25044827 chr16 2595923225959282 chr16 26242030 26242080 chr16 26392043 26392093 chr16 2748935727489407 chr16 27953015 27953065 chr16 28013983 28014033 chr16 2886044628860496 chr16 29044602 29044652 chr16 29249802 29249852 chr16 2968937829689428 chr16 29711162 29711212 chr10 72609960 72610010 chr16 3064548030645530 chr16 31161506 31161556 chr16 31316426 31316476 chr16 3243120732431257 chr16 33088230 33088280 chr16 35547534 35547584 chr16 4734097747341027 chr16 47904620 47904670 chr16 48510154 48510204 chr16 4891647248916522 chr16 49584112 49584162 chr16 49709413 49709463 chr16 5030318050303230 chr16 50314824 50314874 chr16 50314726 50314776 chr16 5063049450630544 chr16 51131489 51131539 chr10 73026693 73026743 chr10 7302997173030021 chr16 52094190 52094240 chr16 52458502 52458552 chr16 5262788852627938 chr16 53693173 53693223 chr16 54246446 54246496 chr10 7314171373141763 chr16 54982509 54982559 chr10 73143055 73143105 chr16 5642500856425058 chr16 56517372 56517422 chr16 56641272 56641322 chr16 5664103556641085 chr16 56812768 56812818 chr16 57102137 57102187 chr16 5730231857302368 chr16 57892858 57892908 chr16 58045928 58045978 chr16 5806454858064598 chr16 58827236 58827286 chr16 59177054 59177104 chr16 5935852359358573 chr16 60128242 60128292 chr16 60377051 60377101 chr16 6058334660583396 chr16 61276410 61276460 chr16 62308324 62308374 chr16 6347637963476429 chr16 63735085 63735135 chr16 64233038 64233088 chr16 6516688565166935 chr16 65774678 65774728 chr16 66771987 66772037 chr10 7371529473715344 chr16 68066143 68066193 chr16 68134896 68134946 chr16 6813469268134742 chr16 68431780 68431830 chr16 68519867 68519917 chr10 7416252874162578 chr10 74162678 74162728 chr16 71960695 71960745 chr16 7222992372229973 chr16 73715126 73715176 chr16 73831487 73831537 chr16 7405666474056714 chr16 74373896 74373946 chr16 74424697 74424747 chr16 7442718974427239 chr16 74428599 74428649 chr16 75011723 75011773 chr16 7520691575206965 chr16 75369771 75369821 chr16 75370295 75370345 chr16 7540692275406972 chr16 76606585 76606635 chr16 77821794 77821844 chr16 7836591878365968 chr16 78366034 78366084 chr16 78584074 78584124 chr16 8096288980962939 chr16 81017100 81017150 chr16 81037517 81037567 chr16 8110063381100683 chr16 81100461 81100511 chr16 81182986 81183036 chr16 8151498281515032 chr16 81527362 81527412 chr16 81573361 81573411 chr10 7473314974733199 chr10 74734188 74734238 chr10 74734335 74734385 chr16 8210763782107687 chr16 83888882 83888932 chr16 83888801 83888851 chr16 8401162384011673 chr16 84011832 84011882 chr10 3305135 3305185 chr16 8428069184280741 chr16 84280607 84280657 chr16 84298435 84298485 chr16 8433281084332860 chr16 84338656 84338706 chr10 3304915 3304965 chr16 8444781284447862 chr16 84481354 84481404 chr16 84489047 84489097 chr16 8449104884491098 chr16 84728664 84728714 chr16 84811886 84811936 chr16 8508402285084072 chr16 85512859 85512909 chr16 85629175 85629225 chr16 8570744285707492 chr16 85827346 85827396 chr16 85848601 85848651 chr16 8600328886003338 chr10 74995980 74996030 chr16 86297677 86297727 chr16 8650954686509596 chr16 86510181 86510231 chr16 86590171 86590221 chr16 8674499986745049 chr16 86960616 86960666 chr16 87357200 87357250 chr16 8747189587471945 chr16 87615363 87615413 chr16 87982180 87982230 chr16 8820351788203567 chr16 88501752 88501802 chr16 88501610 88501660 chr16 8856559688565646 chr16 88576639 88576689 chr10 75337469 75337519 chr16 8866118388661233 chr10 75378179 75378229 chr16 88816640 88816690 chr16 8883192488831974 chr16 89029919 89029969 chr16 89108789 89108839 chr16 8913429489134344 chr16 89157226 89157276 chr17 150299 150349 chr17 279849 279899chr17 302959 303009 chr17 326904 326954 chr17 449625 449675 chr1076048646 76048696 chr17 876295 876345 chr17 946990 947040 chr17 19280941928144 chr10 76264354 76264404 chr17 2726633 2726683 chr10 7647162376471673 chr10 76477370 76477420 chr17 4230259 4230309 chr17 45140934514143 chr17 4707966 4708016 chr17 4759712 4759762 chr17 52085235208573 chr17 5288332 5288382 chr17 5322864 5322914 chr17 53937095393759 chr17 5894374 5894424 chr17 5940066 5940116 chr17 60338626033912 chr17 6500221 6500271 chr17 6976142 6976192 chr17 71855427185592 chr17 7198008 7198058 chr17 7252371 7252421 chr17 72644927264542 chr17 8047310 8047360 chr17 8157601 8157651 chr17 89677048967754 chr17 9430508 9430558 chr17 9563207 9563257 chr17 95975229597572 chr17 9837645 9837695 chr17 10089313 10089363 chr17 1018921210189262 chr17 10368507 10368557 chr17 11166569 11166619 chr17 1121855511218605 chr17 11222994 11223044 chr17 11711370 11711420 chr17 1245660312456653 chr17 12501162 12501212 chr17 12533832 12533882 chr17 1296369112963741 chr17 13375774 13375824 chr17 13923277 13923327 chr17 1447341514473465 chr17 14626539 14626589 chr17 14875668 14875718 chr17 1490200614902056 chr17 14938767 14938817 chr17 14939913 14939963 chr17 1511482015114870 chr17 15121388 15121438 chr17 15582313 15582363 chr17 1558237415582424 chr17 15619490 15619540 chr17 15619291 15619341 chr10 7932163779321687 chr10 79412445 79412495 chr17 18921594 18921644 chr17 1917806019178110 chr17 19551164 19551214 chr17 20050062 20050112 chr17 2005235920052409 chr17 20061485 20061535 chr17 21122596 21122646 chr17 2115119121151241 chr17 21179866 21179916 chr17 21189114 21189164 chr17 2574819425748244 chr17 26390770 26390820 chr17 26902719 26902769 chr17 2692738726927437 chr17 26929269 26929319 chr17 27276932 27276982 chr17 2811641328116463 chr17 28244775 28244825 chr17 28521726 28521776 chr17 2880799728808047 chr17 28807937 28807987 chr10 3737554 3737604 chr17 2905955429059604 chr17 29253046 29253096 chr17 29586799 29586849 chr17 3032924430329294 chr17 31443010 31443060 chr17 31442768 31442818 chr17 3277111932771169 chr17 33207952 33208002 chr17 33244388 33244438 chr17 3388022633880276 chr17 34232256 34232306 chr17 34367305 34367355 chr17 3447342234473472 chr17 34473309 34473359 chr17 34615934 34615984 chr17 3639635036396400 Table 15J. Repeat Category ERVL-B4 chr17 79663446 79663496chr17 81655590 81655640 chr17 81656186 81656236 chr10 93836012 93836062chr18 11714572 11714622 chr18 50286093 50286143 chr19 9703332 9703382chr19 19734668 19734718 chr19 19735950 19736000 chr19 38367114 38367164chr19 48561987 48562037 chr10 107159974 107160024 chr19 4921367349213723 chr19 49306890 49306940 chr19 49307169 49307219 chr10 113008190113008240 chr19 59498707 59498757 chr19 59499175 59499225 chr19 5949863659498686 chr19 60418163 60418213 chr1 2703433 2703483 chr1 2100171321001763 chr1 21003911 21003961 chr1 21005323 21005373 chr1 3237337732373427 chr1 88570535 88570585 chr1 95190210 95190260 chr1 9519164495191694 chr1 228742319 228742369 chr20 62233155 62233205 chr21 2703514127035191 chr21 37597268 37597318 chr11 1056228 1056278 chr21 4634397946344029 chr22 39559437 39559487 chr22 47417932 47417982 chr22 4922791149227961 chrX 63508636 63508686 chrX 86326808 86326858 chrX 8758018987580239 chrX 92919015 92919065 chrX 129503557 129503607 chrX 129510700129510750 chrX 133454977 133455027 chrX 133512850 133512900 chrX133547781 133547831 chrX 133702475 133702525 chrY 14172419 14172469 chr211623095 11623145 chr2 21558215 21558265 chr2 62066404 62066454 chr269520571 69520621 chr2 95464653 95464703 chr2 95477329 95477379 chr2107875411 107875461 chr2 113474853 113474903 chr11 32458605 32458655chr2 130362224 130362274 chr2 159005532 159005582 chr2 242834373242834423 chr3 34926802 34926852 chr3 46283027 46283077 chr3 8285643382856483 chr3 83845963 83846013 chr3 185581029 185581079 chr4 66217956621845 chr4 112556663 112556713 chr4 125498823 125498873 chr4 167234601167234651 chr4 179331312 179331362 chr4 188128051 188128101 chr1169193964 69194014 chr5 23271333 23271383 chr5 30253349 30253399 chr549942088 49942138 chr5 61025428 61025478 chr5 80392512 80392562 chr1171074451 71074501 chr11 78047790 78047840 chr6 33695868 33695918 chr666232320 66232370 chr6 86911446 86911496 chr6 94803351 94803401 chr1015438107 15438157 chr6 170646790 170646840 chr7 3626885 3626935 chr722895240 22895290 chr7 51145436 51145486 chr7 52684086 52684136 chr795344897 95344947 chr7 122154571 122154621 chr7 133619782 133619832 chr7134627117 134627167 chr7 150811812 150811862 chr7 152190369 152190419chr7 156587986 156588036 chr11 120472979 120473029 chr8 2291633022916380 chr8 23215788 23215838 chr8 50201883 50201933 chr8 103140451103140501 chr8 123895484 123895534 chr8 144932498 144932548 chr8144933507 144933557 chr9 29502206 29502256 chr9 30288992 30289042 chr930290641 30290691 chr9 90092279 90092329 chr9 95171099 95171149 chr9127906594 127906644 chr12 7008041 7008091 chr12 8829758 8829808 chr1263239144 63239194 chr12 89113498 89113548 chr12 102529369 102529419chr12 103070260 103070310 chr12 131715407 131715457 chr13 1828204318282093 chr13 27177944 27177994 chr10 37023962 37024012 chr10 4262588042625930 chr13 109395606 109395656 chr10 52058632 52058682 chr10 19324971932547 chr14 103554769 103554819 chr15 28877693 28877743 chr16 31803863180436 chr10 3015419 3015469 chr16 35547534 35547584 chr16 5642500856425058 chr16 86003288 86003338 chr16 88203517 88203567 chr17 876295876345 Table 15K. Repeat Category GSAT chr1 140839821 140839871 chr1140841172 140841222 chr1 140842296 140842346 chr21 14367127 14367177chr22 14476328 14476378 chr22 14476980 14477030 chr22 14477878 14477928chr22 14478232 14478282 chrX 57249652 57249702 chrX 57252055 57252105chrX 57253098 57253148 chrX 57255768 57255818 chrX 57258572 57258622chr2 31403726 31403776 chr2 132723394 132723444 chr3 174852694 174852744chr4 7062858 7062908 chr4 49434782 49434832 chr4 49435470 49435520 chr5177837223 177837273 chr8 43417880 43417930 chr8 43418739 43418789 chr843420187 43420237 chr8 43421368 43421418 chr8 43423341 43423391 chr843436146 43436196 chr8 46947006 46947056 chr8 47032918 47032968 chr847039361 47039411 chr8 47042168 47042218 chr8 47057029 47057079 chr847063194 47063244 chr8 47065152 47065202 chr8 47069102 47069152 chr847070617 47070667 chr8 47074813 47074863 chr8 47105806 47105856 chr847110603 47110653 chr8 47121169 47121219 chr8 47122261 47122311 chr847126219 47126269 chr8 47129687 47129737 chr8 47131011 47131061 chr847136244 47136294 chr8 47142204 47142254 chr8 47144188 47144238 chr847145885 47145935 chr8 47147133 47147183 chr8 47148295 47148345 chr847157918 47157968 chr8 47159194 47159244 chr8 47162521 47162571 chr847163587 47163637 chr8 47164854 47164904 chr8 47168722 47168772 chr847171751 47171801 chr8 47172827 47172877 chr8 47177504 47177554 chr847178335 47178385 chr8 47183041 47183091 chr8 47189273 47189323 chr847189098 47189148 chr8 47191211 47191261 chr8 47204227 47204277 chr847307555 47307605 chr8 47335857 47335907 chr8 47340466 47340516 chr847344331 47344381 chr8 47352798 47352848 chr8 47359859 47359909 chr847361658 47361708 chr8 47365194 47365244 chr8 47366498 47366548 chr847375191 47375241 chr9 43172902 43172952 chr9 43174537 43174587 chr943176252 43176302 chr9 63427466 63427516 chr9 64968296 64968346 chr964971276 64971326 chr12 34255417 34255467 chr12 34333749 34333799 chr1234335653 34335703 chr12 34337071 34337121 chr12 34340101 34340151 chr1234344148 34344198 chr12 34346821 34346871 chr12 34348414 34348464 chr1234349452 34349502 chr12 34351406 34351456 chr12 34355131 34355181 chr1234356000 34356050 chr12 34357433 34357483 chr12 34361478 34361528 chr1234365891 34365941 chr12 34368023 34368073 chr12 34370145 34370195 chr1234371879 34371929 chr12 34373142 34373192 chr12 34375854 34375904 chr1234376598 34376648 chr12 34381192 34381242 chr12 34384507 34384557 chr1234386405 34386455 chr12 34388750 34388800 chr12 34391121 34391171 chr1234397175 34397225 chr12 34398620 34398670 chr12 34400674 34400724 chr1234402377 34402427 chr12 34403978 34404028 chr12 34407067 34407117 chr1234410197 34410247 chr12 34411525 34411575 chr12 34413190 34413240 chr1234415055 34415105 chr12 34415954 34416004 chr12 34418034 34418084 chr1234420630 34420680 chr12 34421456 34421506 chr12 34422708 34422758 chr1234423824 34423874 chr12 34425483 34425533 chr12 34427806 34427856 chr1234429072 34429122 chr12 34436147 34436197 chr12 34437394 34437444 chr1234442947 34442997 chr12 34446019 34446069 chr12 34447767 34447817 chr1234642395 34642445 chr12 34644020 34644070 chr12 34645336 34645386 chr1234646060 34646110 chr12 34648711 34648761 chr12 34649045 34649095 chr1234650600 34650650 chr12 36832980 36833030 chr12 36835270 36835320 chr1236837781 36837831 chr12 36838599 36838649 chr12 36840393 36840443 chr1317317122 17317172 chr17 3875990 3876040 Table 15L. Repeat CategoryGSATII chr1 140839821 140839871 chr1 140841172 140841222 chr1 140842296140842346 chr22 14476328 14476378 chr22 14476980 14477030 chr22 1447787814477928 chr22 14478232 14478282 chr2 132723394 132723444 chr4 4943478249434832 chr4 49435470 49435520 chr9 43172902 43172952 chr9 4317453743174587 chr9 43176252 43176302 chr9 63427466 63427516 chr9 6496829664968346 chr9 64971276 64971326 chr12 34255417 34255467 chr12 3433374934333799 chr12 34335653 34335703 chr12 34337071 34337121 chr12 3434010134340151 chr12 34344148 34344198 chr12 34346821 34346871 chr12 3434841434348464 chr12 34349452 34349502 chr12 34351406 34351456 chr12 3435513134355181 chr12 34356000 34356050 chr12 34357433 34357483 chr12 3436147834361528 chr12 34365891 34365941 chr12 34368023 34368073 chr12 3437014534370195 chr12 34371879 34371929 chr12 34373142 34373192 chr12 3437585434375904 chr12 34376598 34376648 chr12 34381192 34381242 chr12 3438450734384557 chr12 34386405 34386455 chr12 34388750 34388800 chr12 3439112134391171 chr12 34397175 34397225 chr12 34398620 34398670 chr12 3440067434400724 chr12 34402377 34402427 chr12 34403978 34404028 chr12 3440706734407117 chr12 34410197 34410247 chr12 34411525 34411575 chr12 3441319034413240 chr12 34415055 34415105 chr12 34415954 34416004 chr12 3441803434418084 chr12 34420630 34420680 chr12 34421456 34421506 chr12 3442270834422758 chr12 34423824 34423874 chr12 34425483 34425533 chr12 3442780634427856 chr12 34429072 34429122 chr12 34436147 34436197 chr12 3443739434437444 chr12 34442947 34442997 chr12 34446019 34446069 chr12 3444776734447817 chr12 34642395 34642445 chr12 34644020 34644070 chr12 3464533634645386 chr12 34646060 34646110 chr12 34648711 34648761 chr12 3464904534649095 chr12 34650600 34650650 Table 15M. Repeat Category Harlequinchr17 41688008 41688058 chr17 41692469 41692519 chr17 48971947 48971997chr10 85592925 85592975 chr10 85596390 85596440 chr10 85596099 85596149chr10 85595842 85595892 chr17 79083734 79083784 chr17 79084761 79084811chr18 10593595 10593645 chr10 95813106 95813156 chr18 51771480 51771530chr18 67288389 67288439 chr10 98985580 98985630 chr19 6548612 6548662chr19 9679912 9679962 chr19 19757388 19757438 chr19 20217989 20218039chr19 20980348 20980398 chr19 20987672 20987722 chr19 20990030 20990080chr19 33790221 33790271 chr19 57889039 57889089 chr19 58094810 58094860chr19 58152373 58152423 chr1 1301672 1301722 chr1 35040144 35040194 chr146167580 46167630 chr1 91139029 91139079 chr1 91141099 91141149 chr191602320 91602370 chr1 91607444 91607494 chr1 165020614 165020664 chr1208944583 208944633 chr1 217947911 217947961 chr1 217952712 217952762chr1 224754280 224754330 chr1 244966320 244966370 chr20 1596126615961316 chr21 20292040 20292090 chr21 32952678 32952728 chr21 4324838943248439 chr21 43250115 43250165 chrX 9967063 9967113 chrX 4775991547759965 chrX 47764086 47764136 chrX 52510059 52510109 chrX 5251367552513725 chrX 113537475 113537525 chrX 113541216 113541266 chrX113543646 113543696 chrX 113821185 113821235 chrY 14403477 14403527 chrY17890936 17890986 chr2 13687966 13688016 chr2 13695140 13695190 chr265089272 65089322 chr2 65089956 65090006 chr2 65090170 65090220 chr265101094 65101144 chr2 106217414 106217464 chr2 188583849 188583899 chr2209182252 209182302 chr2 214474051 214474101 chr2 214477356 214477406chr3 865355 865405 chr3 20387292 20387342 chr3 121351668 121351718 chr1160639025 60639075 chr3 135060147 135060197 chr4 8628791 8628841 chr48629462 8629512 chr4 8633179 8633229 chr4 22351979 22352029 chr436805197 36805247 chr4 70232770 70232820 chr4 70232602 70232652 chr493425519 93425569 chr4 159727410 159727460 chr4 174716255 174716305 chr542859327 42859377 chr5 64486100 64486150 chr5 64490718 64490768 chr581649376 81649426 chr5 81653083 81653133 chr5 116118192 116118242 chr5138935066 138935116 chr11 74482411 74482461 chr5 158774642 158774692chr5 162727134 162727184 chr11 81389164 81389214 chr6 26183592 26183642chr6 35016783 35016833 chr6 47649941 47649991 chr6 75174105 75174155chr6 111653619 111653669 chr11 97805236 97805286 chr7 4805043 4805093chr7 4806585 4806635 chr7 4807691 4807741 chr7 10711055 10711105 chr724577109 24577159 chr7 30590054 30590104 chr7 100048567 100048617 chr7102353546 102353596 chr7 127795349 127795399 chr7 136364655 136364705chr7 136369064 136369114 chr8 41468393 41468443 chr8 41471654 41471704chr8 54486289 54486339 chr8 54486391 54486441 chr8 56675871 56675921chr8 59653843 59653893 chr8 144863318 144863368 chr8 144866035 144866085chr8 144868006 144868056 chr12 8492990 8493040 chr12 32071135 32071185chr12 48414803 48414853 chr12 71498252 71498302 chr12 71503639 71503689chr10 30769582 30769632 chr13 21259309 21259359 chr13 65771389 65771439chr13 65777169 65777219 chr10 60835403 60835453 chr10 60869487 60869537chr10 73044293 73044343 Table 15N. Repeat Category HERV9 chr17 7350050373500553 chr17 73502106 73502156 chr10 90831550 90831600 chr18 48062004806250 chr18 5076788 5076838 chr10 96197497 96197547 chr19 83509468350996 chr19 18555519 18555569 chr19 44005505 44005555 chr19 4400579544005845 chr19 44006124 44006174 chr19 44006438 44006488 chr19 4514385345143903 chr19 45145464 45145514 chr1 6330271 6330321 chr1 63336736333723 chr10 117925907 117925957 chr1 58003791 58003841 chr1 6259072262590772 chr1 62591082 62591132 chr1 62591469 62591519 chr1 6626200766262057 chr1 102673199 102673249 chr1 105009493 105009543 chr1119061757 119061807 chr1 119063336 119063386 chr1 151862317 151862367chr1 172315523 172315573 chr1 196350746 196350796 chr20 4022545240225502 chr21 29648303 29648353 chrX 25877374 25877424 chrX 102899430102899480 chrX 113507179 113507229 chrX 114159564 114159614 chrX116169376 116169426 chrY 15010206 15010256 chrY 15714739 15714789 chr29058138 9058188 chr2 21299682 21299732 chr2 33252847 33252897 chr233256063 33256113 chr2 47302706 47302756 chr2 47303895 47303945 chr263524436 63524486 chr2 63525488 63525538 chr2 63527836 63527886 chr1123922340 23922390 chr11 23927165 23927215 chr2 164126675 164126725 chr2184953385 184953435 chr11 38102714 38102764 chr2 203564551 203564601chr11 42861632 42861682 chr2 242127537 242127587 chr2 242127273242127323 chr3 9595278 9595328 chr3 9599612 9599662 chr3 2028705120287101 chr3 33460626 33460676 chr3 38441934 38441984 chr3 4921983049219880 chr3 51843981 51844031 chr3 56710325 56710375 chr3 9663475496634804 chr3 149610248 149610298 chr3 150323777 150323827 chr3152709083 152709133 chr3 153600090 153600140 chr3 163613973 163614023chr3 164841947 164841997 chr4 24997332 24997382 chr4 24998346 24998396chr4 45449397 45449447 chr4 59240331 59240381 chr4 63922678 63922728chr4 71006856 71006906 chr4 77429274 77429324 chr4 103010781 103010831chr4 132227868 132227918 chr4 160157147 160157197 chr4 160163810160163860 chr11 67163610 67163660 chr5 49682936 49682986 chr5 5492724654927296 chr5 96727232 96727282 chr5 125633601 125633651 chr5 125634821125634871 chr5 130046591 130046641 chr5 144256216 144256266 chr5157288569 157288619 chr5 157294830 157294880 chr6 9831174 9831224 chr619380476 19380526 chr11 84534139 84534189 chr11 85044385 85044435 chr638631973 38632023 chr6 38638804 38638854 chr6 52873056 52873106 chr664039538 64039588 chr6 64731695 64731745 chr6 74609656 74609706 chr6116458435 116458485 chr6 116459467 116459517 chr11 96045911 96045961chr6 141485259 141485309 chr11 100648542 100648592 chr11 102751565102751615 chr7 23637191 23637241 chr7 36984863 36984913 chr7 6355212763552177 chr7 81883546 81883596 chr7 143513210 143513260 chr8 44292204429270 chr8 11177208 11177258 chr8 27371989 27372039 chr8 2918498729185037 chr8 50618557 50618607 chr8 73350754 73350804 chr8 7487488774874937 chr8 100132498 100132548 chr9 22426217 22426267 chr9 2681641326816463 chr9 84228794 84228844 chr12 1695379 1695429 chr12 88331528833202 chr12 18083947 18083997 chr12 20821865 20821915 chr12 2942950529429555 chr12 31981044 31981094 chr12 81269085 81269135 chr12 106108037106108087 chr12 106718560 106718610 chr10 31194356 31194406 chr1321898560 21898610 chr13 98429093 98429143 chr13 98636368 98636418 chr13106246891 106246941 chr13 109546410 109546460 chr14 22095947 22095997chr14 79969950 79970000 chr10 55400187 55400237 chr10 58945869 58945919chr15 42870466 42870516 chr15 43019410 43019460 chr10 65888931 65888981chr16 21608058 21608108 chr16 21613682 21613732 Table 15O. RepeatCategory HERVFH21 chr19 19916932 19916982 chr1 6333673 6333723 chr16334500 6334550 chr1 6336594 6336644 chr1 6337256 6337306 chr1 63382476338297 chr1 6338700 6338750 chr1 8691734 8691784 chr1 8695896 8695946chr1 8695658 8695708 chr1 36224419 36224469 chr1 36227399 36227449 chr136230083 36230133 chr1 144512253 144512303 chr1 154460528 154460578 chr1154465550 154465600 chr11 3338103 3338153 chr11 3342619 3342669 chr115915252 5915302 chr11 5917222 5917272 chr11 5918320 5918370 chrY13412083 13412133 chrY 13416775 13416825 chr2 62126818 62126868 chr1131594478 31594528 chr11 58787567 58787617 chr3 142738000 142738050 chr3142741496 142741546 chr3 152845697 152845747 chr3 165063501 165063551chr5 29436941 29436991 chr5 165536408 165536458 chr6 17428373 17428423chr6 17430481 17430531 chr6 17431369 17431419 chr6 17435075 17435125chr7 12373055 12373105 chr7 12373469 12373519 chr7 12378141 12378191chr7 63707360 63707410 chr7 63710987 63711037 chr7 64353237 64353287chr7 64354507 64354557 chr7 152500346 152500396 chr7 152501738 152501788chr8 48951898 48951948 chr8 48953354 48953404 chr8 48960445 48960495chr12 111641372 111641422 chr14 100691478 100691528 chr14 100703440100703490 chr14 100704576 100704626 chr16 30590321 30590371 chr1630592221 30592271 chr16 30593884 30593934 chr10 73065984 73066034 chr1073066226 73066276 chr10 73066517 73066567 chr10 73066592 73066642 chr1073067037 73067087 Table 15P. Repeat Category HERVK11 chr18 7012360870123658 chr10 104264539 104264589 chr10 104264619 104264669 chr10104264710 104264760 chr10 104267695 104267745 chr1 109545458 109545508chr1 109549553 109549603 chr1 157877337 157877387 chr1 208652478208652528 chr22 18297951 18298001 chr22 18299679 18299729 chr22 1830238918302439 chrX 34176612 34176662 chrX 45394539 45394589 chrX 5594707055947120 chr2 64192256 64192306 chr2 77315804 77315854 chr2 101481794101481844 chr3 131491371 131491421 chr3 168222061 168222111 chr4 41136084113658 chr4 81207097 81207147 chr4 81206931 81206981 chr4 141132783141132833 chr11 67242926 67242976 chr11 67247088 67247138 chr4 166247883166247933 chr4 166249950 166250000 chr5 54688468 54688518 chr6 106108380106108430 chr6 121344741 121344791 chr7 50387172 50387222 chr8 2919524529195295 chr8 89645119 89645169 chr9 31762122 31762172 chr9 110540653110540703 chr12 82998661 82998711 chr12 83004551 83004601 chr16 39695463969596 Table 15Q. Repeat Category HERVK14 chr17 73616199 73616249 chr1773621355 73621405 chr17 73623410 73623460 chr19 12424237 12424287 chr1924145792 24145842 chr19 56594884 56594934 chr19 63101807 63101857 chr1963104294 63104344 chr19 63106137 63106187 chr1 62014127 62014177 chr1203009281 203009331 chr1 203009106 203009156 chr1 222955002 222955052chr1 222959363 222959413 chr1 222961831 222961881 chr1 222962980222963030 chr1 244216642 244216692 chr22 24135046 24135096 chr2229396210 29396260 chr22 29398342 29398392 chr22 29400220 29400270 chrX116182682 116182732 chrX 116188297 116188347 chrY 7697268 7697318 chrY13455713 13455763 chrY 22454225 22454275 chrY 22458742 22458792 chrY22458853 22458903 chr2 82225138 82225188 chr2 128468837 128468887 chr2181124049 181124099 chr2 217138311 217138361 chr11 55875311 55875361chr3 173758124 173758174 chr3 173759285 173759335 chr4 176606965176607015 chr5 23733108 23733158 chr5 24353855 24353905 chr5 3144043331440483 chr5 31444280 31444330 chr11 73382443 73382493 chr6 4888893148888981 chr6 48892648 48892698 chr6 79559788 79559838 chr6 126213455126213505 chr6 134906416 134906466 chr6 166668349 166668399 chr7 88011798801229 chr7 8804044 8804094 chr11 120645173 120645223 chr9 2964984629649896 chr9 29770178 29770228 chr12 45585167 45585217 chr12 4719053747190587 chr12 47190332 47190382 chr12 47191786 47191836 chr12 4719164947191699 chr10 42266499 42266549 chr13 63081280 63081330 chr13 9139012491390174 chr15 60222264 60222314 chr15 74275229 74275279 chr16 1937905519379105 chr10 73065984 73066034 Table 15R. Repeat Category HERVK22chr18 25255495 25255545 chr19 23532349 23532399 chr19 32928882 32928932chr19 32930010 32930060 chr19 32929918 32929968 chr19 32932324 32932374chr19 47892385 47892435 chr19 47892649 47892699 chr19 47893498 47893548chr19 47893919 47893969 chr19 47894016 47894066 chr19 47894490 47894540chr19 57854025 57854075 chr1 86396110 86396160 chr1 153375315 153375365chr1 156138608 156138658 chr1 158096865 158096915 chr1 168460105168460155 chr1 239322614 239322664 chr20 25602563 25602613 chrX 2559821625598266 chrX 62872118 62872168 chrX 63282890 63282940 chrX 9251986392519913 chrX 92519608 92519658 chrX 92522265 92522315 chrX 145018136145018186 chrX 145020894 145020944 chrX 147470265 147470315 chrY20926896 20926946 chr2 71590282 71590332 chr2 71595325 71595375 chr2128222110 128222160 chr2 167668621 167668671 chr2 167669823 167669873chr2 232163770 232163820 chr2 232168171 232168221 chr11 5847066558470715 chr11 58470350 58470400 chr3 171116443 171116493 chr3 186599533186599583 chr4 136786588 136786638 chr4 136788228 136788278 chr526892790 26892840 chr5 37132931 37132981 chr11 80470448 80470498 chr1180475408 80475458 chr6 26367620 26367670 chr6 56986133 56986183 chr665010255 65010305 chr6 101439809 101439859 chr11 95355336 95355386 chr1195360550 95360600 chr7 39663241 39663291 chr7 106587234 106587284 chr847583088 47583138 chr8 89580634 89580684 chr8 89580484 89580534 chr998509088 98509138 chr9 98510946 98510996 chr12 8602302 8602352 chr1241122714 41122764 chr12 41126148 41126198 chr12 68011122 68011172 chr1287080333 87080383 chr12 94342775 94342825 chr12 99060281 99060331 chr1299060182 99060232 chr12 99061198 99061248 chr13 23299768 23299818 chr1323299820 23299870 chr10 43084179 43084229 chr10 43084465 43084515 chr1043084735 43084785 chr10 43085253 43085303 chr10 43085538 43085588 chr1478921071 78921121 chr14 105126835 105126885 chr14 105126736 105126786chr15 37021929 37021979 chr15 37021655 37021705 chr15 47847615 47847665chr15 52895510 52895560 Table 15S. Repeat Category HERVK9 chr17 4772818247728232 chr19 9426058 9426108 chr19 44123445 44123495 chr19 4412355144123601 chr1 19337955 19338005 chr10 120038656 120038706 chr1 4835508748355137 chr1 54466355 54466405 chr1 54470375 54470425 chr1 140694238140694288 chr1 141061552 141061602 chr1 141331391 141331441 chr2023443196 23443246 chrX 73410922 73410972 chrX 73410727 73410777 chrX73414467 73414517 chrX 78054225 78054275 chrY 14373702 14373752 chr220107539 20107589 chr2 20110072 20110122 chr2 48587291 48587341 chr256921191 56921241 chr2 153237365 153237415 chr2 153239665 153239715 chr2184120362 184120412 chr2 219179971 219180021 chr3 38423302 38423352 chr338425563 38425613 chr3 130945368 130945418 chr3 130945427 130945477 chr3186056639 186056689 chr4 92565890 92565940 chr4 155192336 155192386 chr4186666592 186666642 chr4 186668148 186668198 chr5 295513 295563 chr51636141 1636191 chr5 34832555 34832605 chr5 121272595 121272645 chr66013296 6013346 chr6 45250837 45250887 chr6 67036583 67036633 chr693903878 93903928 chr7 42416386 42416436 chr7 43644071 43644121 chr745507361 45507411 chr7 55959316 55959366 chr7 154422874 154422924 chr853946006 53946056 chr8 93206494 93206544 chr8 146103607 146103657 chr9129832348 129832398 chr9 129833786 129833836 chr12 37880721 37880771chr12 49178322 49178372 chr12 50419640 50419690 chr12 53957670 53957720chr12 93252455 93252505 chr12 104200372 104200422 chr12 104204812104204862 chr13 19056838 19056888 chr13 21275891 21275941 chr10 4227636642276416 chr14 55823217 55823267 chr14 101691027 101691077 chr14101692650 101692700 chr15 21493283 21493333 chr15 87508917 87508967chr15 87512657 87512707 chr10 69967970 69968020 chr10 69969376 69969426chr10 69971039 69971089 chr10 69972473 69972523 chr16 3127347 3127397chr16 3131557 3131607 chr17 21145322 21145372 chr17 28459509 28459559Table 15T. Repeat Category HERVL chr17 42575356 42575406 chr17 5911205859112108 chr18 2823661 2823711 chr10 4757976 4758026 chr18 2763094527630995 chr18 33712437 33712487 chr18 39314666 39314716 chr18 3933113039331180 chr18 39330976 39331026 chr18 62808467 62808517 chr18 6733249967332549 chr19 9710880 9710930 chr19 12058125 12058175 chr19 1983425719834307 chr19 20023775 20023825 chr19 20041410 20041460 chr19 2004495920045009 chr19 20125977 20126027 chr19 43476713 43476763 chr19 4347824443478294 chr19 54422177 54422227 chr19 54476385 54476435 chr19 5699653456996584 chr19 58225411 58225461 chr19 58226657 58226707 chr19 5870158058701630 chr1 4320728 4320778 chr1 8706643 8706693 chr1 1568376915683819 chr1 28673990 28674040 chr1 31486513 31486563 chr1 3148582131485871 chr1 35190033 35190083 chr1 79938727 79938777 chr1 7993896579939015 chr1 79939292 79939342 chr1 79939829 79939879 chr1 7994007079940120 chr1 85280755 85280805 chr1 88529129 88529179 chr1 107467789107467839 chr1 111132109 111132159 chr1 113907964 113908014 chr1117710217 117710267 chr1 117710017 117710067 chr1 158619615 158619665chr1 158619006 158619056 chr1 185549613 185549663 chr1 196235232196235282 chr1 204680138 204680188 chr1 204680639 204680689 chr1204681551 204681601 chr1 223698589 223698639 chr1 223705042 223705092chr1 244141539 244141589 chr1 244143609 244143659 chr1 244255088244255138 chr20 2651528 2651578 chr20 2968225 2968275 chr20 3353801333538063 chr10 133920653 133920703 chr10 134663497 134663547 chr2129145010 29145060 chr21 29156309 29156359 chr22 17463493 17463543 chr2221067166 21067216 chr22 21432174 21432224 chr22 31477700 31477750 chr2240454531 40454581 chr22 44231708 44231758 chrX 4151370 4151420 chrX4153605 4153655 chrX 8471941 8471991 chrX 19416489 19416539 chrX37636313 37636363 chrX 39716439 39716489 chrX 39720531 39720581 chrX46518193 46518243 chrX 71958452 71958502 chrX 84928330 84928380 chrX101309114 101309164 chrX 101885783 101885833 chrX 106492964 106493014chrX 125725267 125725317 chrX 147322032 147322082 chrX 147321813147321863 chrX 147538903 147538953 chrY 8716577 8716627 chrY 2097966520979715 chrY 20981332 20981382 chr2 24514470 24514520 chr2 3598829035988340 chr11 21798360 21798410 chr2 70405449 70405499 chr2 8038132280381372 chr2 100516923 100516973 chr2 113434220 113434270 chr2128683735 128683785 chr2 162892086 162892136 chr11 39114823 39114873chr11 39330117 39330167 chr2 224369830 224369880 chr2 242278366242278416 chr2 242279651 242279701 chr3 3847958 3848008 chr3 1272826612728316 chr3 19906213 19906263 chr3 46818060 46818110 chr3 4800688648006936 chr11 56165381 56165431 chr3 106644031 106644081 chr3 119403971119404021 chr4 966070 966120 chr4 2773936 2773986 chr4 17676139 17676189chr4 29509997 29510047 chr4 62297442 62297492 chr4 62297235 62297285chr4 67648786 67648836 chr4 84369941 84369991 chr4 95536618 95536668chr4 102996809 102996859 chr4 104125960 104126010 chr4 133470625133470675 chr4 135587729 135587779 chr4 138789336 138789386 chr4139626989 139627039 chr4 140941457 140941507 chr4 166432660 166432710chr4 166432827 166432877 chr4 166625111 166625161 chr4 166625966166626016 chr4 179755826 179755876 chr4 187675052 187675102 chr512392304 12392354 chr5 18342099 18342149 chr5 18839149 18839199 chr523265007 23265057 chr5 26820059 26820109 chr5 43196076 43196126 chr543204176 43204226 chr5 56535353 56535403 chr5 74168616 74168666 chr5101174232 101174282 chr5 101847480 101847530 chr5 106285518 106285568chr5 106287716 106287766 chr5 106325045 106325095 chr5 111453449111453499 chr11 73979736 73979786 chr5 152031779 152031829 chr5160346629 160346679 chr5 160346343 160346393 chr5 160403079 160403129chr6 3876977 3877027 chr11 77590133 77590183 chr6 10244944 10244994 chr621466481 21466531 chr6 28077381 28077431 chr6 28432162 28432212 chr628431869 28431919 chr6 29759374 29759424 chr11 87854950 87855000 chr671271736 71271786 chr6 72895922 72895972 chr11 90082072 90082122 chr680018768 80018818 chr6 80018515 80018565 chr6 90250211 90250261 chr694547928 94547978 chr6 105710211 105710261 chr6 122896591 122896641chr11 96400830 96400880 chr6 132473418 132473468 chr6 133665465133665515 chr11 97183407 97183457 chr6 135174097 135174147 chr6153503258 153503308 chr6 167387267 167387317 chr7 13233606 13233656 chr781443708 81443758 chr7 99741950 99742000 chr7 116598271 116598321 chr7118383067 118383117 chr7 148144855 148144905 chr7 156587986 156588036chr8 2760276 2760326 chr8 5075110 5075160 chr8 5501858 5501908 chr813448334 13448384 chr8 55150706 55150756 chr8 78786789 78786839 chr895268153 95268203 chr8 122480079 122480129 chr9 20504875 20504925 chr975026755 75026805 chr9 76145955 76146005 chr9 76145889 76145939 chr987390311 87390361 chr9 92073065 92073115 chr9 92072981 92073031 chr9110517709 110517759 chr9 132828175 132828225 chr9 134843242 134843292chr9 134960777 134960827 chr12 8040415 8040465 chr12 8043462 8043512chr12 14342962 14343012 chr12 17013608 17013658 chr12 31767862 31767912chr12 49002379 49002429 chr12 49438886 49438936 chr12 86591717 86591767chr12 119458129 119458179 chr10 41968502 41968552 chr13 5886920158869251 chr13 88963769 88963819 chr14 28988650 28988700 chr14 6991759169917641 chr14 69921435 69921485 chr10 52511442 52511492 chr14 7577550875775558 chr10 55208723 55208773 chr14 98627075 98627125 chr14 101717064101717114 chr14 101738835 101738885 chr10 59721874 59721924 chr1519941143 19941193 chr15 21315109 21315159 chr15 51919168 51919218 chr1551918908 51918958 chr15 77699950 77700000 chr15 91370024 91370074 chr1071757549 71757599 chr16 25044777 25044827 chr16 89029919 89029969 chr174230259 4230309 chr17 33880226 33880276 Table 15U. Repeat CategoryHERVL18 chr17 59112058 59112108 chr18 39314666 39314716 chr19 1205812512058175 chr1 79938727 79938777 chr1 79938965 79939015 chr1 7993929279939342 chr1 79939829 79939879 chr1 79940070 79940120 chr1 117710217117710267 chr1 117710017 117710067 chr1 204680138 204680188 chr1204680639 204680689 chr1 204681551 204681601 chr2 35988290 35988340chr11 21798360 21798410 chr2 70405449 70405499 chr2 128683735 128683785chr11 39330117 39330167 chr4 62297442 62297492 chr4 62297235 62297285chr4 179755826 179755876 chr5 18839149 18839199 chr5 101174232 101174282chr5 106285518 106285568 chr5 106287716 106287766 chr11 7397973673979786 chr5 160346629 160346679 chr5 160346343 160346393 chr6 2807738128077431 chr6 28432162 28432212 chr6 28431869 28431919 chr11 8785495087855000 chr6 80018768 80018818 chr6 80018515 80018565 chr6 135174097135174147 chr6 153503258 153503308 chr7 81443708 81443758 chr13 8896376988963819 chr14 28988650 28988700 chr10 59721874 59721924 chr15 5191916851919218 chr15 51918908 51918958 Table 15V. Repeat Category HERVP71Achr10 103617621 103617671 chr10 103618933 103618983 chr10 103621736103621786 chr10 105492007 105492057 chr1 71341164 71341214 chr1 7423093274230982 chr1 244329852 244329902 chr1 244470329 244470379 chrX 9859740898597458 chrX 98603436 98603486 chrX 116773411 116773461 chrX 116778083116778133 chr2 18251662 18251712 chr2 18254293 18254343 chr3 51658865165936 chr5 85027506 85027556 chr5 125336503 125336553 chr6 4340610743406157 chr6 43413274 43413324 chr6 80231919 80231969 chr6 165380628165380678 chr6 165387274 165387324 chr6 165388524 165388574 chr876324035 76324085 chr8 126958920 126958970 chr9 41232777 41232827 chr1287165 87215 chr9 133622612 133622662 chr9 133624416 133624466 chr9133626195 133626245 chr12 3496740 3496790 chr12 7635369 7635419 chr1030855141 30855191 chr13 109286998 109287048 chr10 48887289 48887339chr15 73072346 73072396 chr17 31443010 31443060 chr17 31442768 31442818Table 15W. Repeat Category HUERS-P1 chr17 75396020 75396070 chr1 13399371339987 chr1 19644411 19644461 chr1 20311744 20311794 chr1 9102110991021159 chr1 244491072 244491122 chr21 15101931 15101981 chrX 88592788859328 chrX 92036559 92036609 chr11 10086850 10086900 chr11 1008667710086727 chr11 14162704 14162754 chrY 18474070 18474120 chrY 2051088120510931 chr2 36830885 36830935 chr2 50079611 50079661 chr2 109334729109334779 chr2 134840943 134840993 chr2 154316635 154316685 chr3 96492089649258 chr3 9651861 9651911 chr3 9652843 9652893 chr3 9654111 9654161chr3 9658743 9658793 chr3 40554525 40554575 chr3 44465848 44465898 chr344467363 44467413 chr3 185741472 185741522 chr4 84477183 84477233 chr4101110929 101110979 chr5 87098704 87098754 chr6 68115376 68115426 chr6147840044 147840094 chr11 118264175 118264225 chr7 137120893 137120943chr8 91586803 91586853 chr8 91586500 91586550 chr8 129070264 129070314chr15 67341648 67341698 chr15 87195445 87195495 chr16 8890489 8890539chr17 259399 259449 Table 15X. Repeat Category HUERS-P2 chr17 4247293642472986 chr17 43118925 43118975 chr1 149570165 149570215 chr1 179724329179724379 chr21 22414962 22415012 chr21 22417515 22417565 chr21 4476261844762668 chrX 141948295 141948345 chrX 142111394 142111444 chr1126135587 26135637 chr2 163386958 163387008 chr11 39953860 39953910 chr397742553 97742603 chr3 181907134 181907184 chr4 119212090 119212140 chr4119214821 119214871 chr6 15447666 15447716 chr6 99745335 99745385 chr11115553969 115554019 chr7 144838835 144838885 chr7 144841923 144841973chr8 111029916 111029966 chr9 31798136 31798186 chr12 40982413 40982463chr12 73068993 73069043 chr13 21015943 21015993 chr13 57231476 57231526chr13 60999534 60999584 chr13 86160799 86160849 chr14 39184578 39184628chr10 54045544 54045594 chr10 56368379 56368429 Table 15Y. RepeatCategory HUERS-P3 chr17 52185310 52185360 chr17 64825485 64825535 chr1764826927 64826977 chr17 73126561 73126611 chr17 80977296 80977346 chr1816910157 16910207 chr18 29145825 29145875 chr18 45226069 45226119 chr1875871924 75871974 chr19 23697617 23697667 chr19 58203562 58203612 chr1958203272 58203322 chr19 59878543 59878593 chr19 61552513 61552563 chr127132689 27132739 chr1 32384474 32384524 chr1 102363651 102363701 chr1223656270 223656320 chr1 242390069 242390119 chr1 242390126 242390176chr1 243201130 243201180 chr1 243645834 243645884 chr20 4683750646837556 chr21 19976407 19976457 chr21 36391827 36391877 chr22 2434278424342834 chrX 26033665 26033715 chrX 87789407 87789457 chrX 107984908107984958 chrY 2981340 2981390 chrY 21956934 21956984 chr2 3189028431890334 chr2 108481066 108481116 chr11 34884517 34884567 chr11 3665850736658557 chr11 40087924 40087974 chr2 209462598 209462648 chr2 219417030219417080 chr2 219417931 219417981 chr2 219846914 219846964 chr2229375634 229375684 chr11 59887612 59887662 chr3 143320860 143320910chr3 146297358 146297408 chr3 173712732 173712782 chr3 197577793197577843 chr3 197900167 197900217 chr4 36793379 36793429 chr4 164687848164687898 chr4 164689075 164689125 chr4 164689386 164689436 chr520382016 20382066 chr5 54518737 54518787 chr5 80276520 80276570 chr5126153252 126153302 chr5 140864272 140864322 chr5 142661945 142661995chr11 74320868 74320918 chr5 157127970 157128020 chr5 180514759180514809 chr6 66920360 66920410 chr6 118946792 118946842 chr7 89737818973831 chr7 63492843 63492893 chr7 63495234 63495284 chr8 3481026234810312 chr11 125281717 125281767 chr8 74993381 74993431 chr8 8801420088014250 chr9 14820611 14820661 chr9 14821819 14821869 chr9 1522287715222927 chr9 71698633 71698683 chr5 69006205 69006255 chr5 6900656069006610 chr5 69006678 69006728 chr5 70521542 70521592 chr5 7052199970522049 chr5 70522244 70522294 chr5 70522471 70522521 chr12 76871107687160 chr10 22580498 22580548 chr12 30888859 30888909 chr12 103133770103133820 chr12 107670719 107670769 chr13 23368182 23368232 chr1329762328 29762378 chr13 34739212 34739262 chr10 37618144 37618194 chr1358658405 58658455 chr13 60904274 60904324 chr13 79890439 79890489 chr1629760636 29760686 chr17 16649836 16649886 Table 15Z. Repeat CategoryL1M3f chr10 93169362 93169412 chr18 47332147 47332197 chr18 5819859658198646 chr18 67500685 67500735 chr19 40082048 40082098 chr19 4191308841913138 chr19 59503551 59503601 chr1 150109199 150109249 chr1 157503847157503897 chr1 172118239 172118289 chr1 213541410 213541460 chr2143895296 43895346 chr22 15931991 15932041 chrX 29997181 29997231 chrX29996942 29996992 chrX 72101369 72101419 chrX 74362894 74362944 chrX76433936 76433986 chrX 119043458 119043508 chrX 125731983 125732033 chrY2428455 2428505 chr2 15106266 15106316 chr11 20118143 20118193 chr1120117954 20118004 chr2 141796631 141796681 chr11 34799775 34799825 chr1138187209 38187259 chr2 187849548 187849598 chr2 195190317 195190367 chr2219796563 219796613 chr3 28178932 28178982 chr3 175411275 175411325 chr42151462 2151512 chr4 83317451 83317501 chr4 90725576 90725626 chr4115175721 115175771 chr4 146489913 146489963 chr4 165506205 165506255chr5 62555177 62555227 chr5 82359970 82360020 chr5 93423230 93423280chr5 118503048 118503098 chr5 156258224 156258274 chr6 29093781 29093831chr11 82653958 82654008 chr11 82657767 82657817 chr6 70200833 70200883chr6 114298275 114298325 chr6 122546082 122546132 chr6 127906547127906597 chr11 97201180 97201230 chr7 158146810 158146860 chr8 68938016893851 chr8 60793858 60793908 chr8 65023325 65023375 chr8 104549953104550003 chr9 6856383 6856433 chr9 6857337 6857387 chr9 3558280435582854 chr9 75561423 75561473 chr9 120734474 120734524 chr12 38182993818349 chr12 45986388 45986438 chr12 103819071 103819121 chr12108319593 108319643 chr12 130358782 130358832 chr13 86917615 86917665chr14 32982246 32982296 chr10 48138279 48138329 chr15 38498286 38498336chr15 59697282 59697332 chr15 59904050 59904100 chr16 3388760 3388810chr16 75589928 75589978 chr10 75465252 75465302 chr17 21214505 21214555chr17 21214305 21214355 Table 15AA. Repeat Category L1MA1 chr10 8177107681771126 chr10 81770669 81770719 chr10 83613460 83613510 chr17 4808777848087828 chr17 52098872 52098922 chr17 59590004 59590054 chr17 5979497459795024 chr17 67420693 67420743 chr17 76489363 76489413 chr18 74297237429773 chr18 11638686 11638736 chr18 13054250 13054300 chr18 2500067325000723 chr10 96255336 96255386 chr18 33901594 33901644 chr18 5859158258591632 chr18 64152121 64152171 chr18 72539223 72539273 chr18 7253906772539117 chr19 2045674 2045724 chr19 8208827 8208877 chr19 97765219776571 chr19 12169020 12169070 chr19 17066286 17066336 chr10 103637241103637291 chr19 19106662 19106712 chr19 33900734 33900784 chr19 4404349844043548 chr19 50167812 50167862 chr19 50604758 50604808 chr19 5060570350605753 chr19 51766075 51766125 chr10 111878083 111878133 chr1954204947 54204997 chr19 58441445 58441495 chr19 59600853 59600903 chr1959684475 59684525 chr19 59742363 59742413 chr19 61380295 61380345 chr1962996597 62996647 chr19 63072622 63072672 chr19 63127040 63127090 chr1963212625 63212675 chr1 8139853 8139903 chr1 11137594 11137644 chr111884710 11884760 chr1 14692310 14692360 chr1 18822641 18822691 chr128500574 28500624 chr1 30085553 30085603 chr1 33181608 33181658 chr142096532 42096582 chr1 49847847 49847897 chr1 54687981 54688031 chr163596268 63596318 chr1 71546664 71546714 chr1 81080704 81080754 chr181550129 81550179 chr10 6707061 6707111 chr10 125618608 125618658 chr1100454553 100454603 chr1 100673040 100673090 chr1 100845210 100845260chr1 104263309 104263359 chr1 116751098 116751148 chr1 140642544140642594 chr1 141130625 141130675 chr1 149101991 149102041 chr1154206725 154206775 chr1 154931370 154931420 chr1 155009110 155009160chr1 161292981 161293031 chr1 161513309 161513359 chr1 165111513165111563 chr1 168252976 168253026 chr1 171490144 171490194 chr1173606513 173606563 chr1 177918084 177918134 chr1 178276685 178276735chr1 180188165 180188215 chr1 181519142 181519192 chr1 184425956184426006 chr1 189991703 189991753 chr1 191908143 191908193 chr1192125819 192125869 chr1 194145689 194145739 chr1 199787537 199787587chr1 199787212 199787262 chr1 200139108 200139158 chr1 202968721202968771 chr1 210376216 210376266 chr1 210383109 210383159 chr1216138589 216138639 chr1 221607376 221607426 chr1 238204433 238204483chr1 241978987 241979037 chr1 242244752 242244802 chr1 244656223244656273 chr1 244717207 244717257 chr10 133241280 133241330 chr2021863251 21863301 chr20 41038151 41038201 chr20 44042453 44042503 chr2044919808 44919858 chr20 46802945 46802995 chr10 134099395 134099445chr20 52784186 52784236 chr20 54793262 54793312 chr20 56644484 56644534chr20 61644189 61644239 chr21 30796226 30796276 chr21 33680614 33680664chr21 35042487 35042537 chr22 19406704 19406754 chr22 19406770 19406820chr22 20610320 20610370 chr22 20766708 20766758 chr22 23817293 23817343chr22 27160284 27160334 chr22 28549951 28550001 chr22 32451827 32451877chr22 33261197 33261247 chr11 2067037 2067087 chrX 8056752 8056802 chr115462868 5462918 chrX 22928822 22928872 chrX 23606381 23606431 chrX31140711 31140761 chrX 33173422 33173472 chrX 33187273 33187323 chrX33213000 33213050 chrX 36931109 36931159 chrX 40529545 40529595 chrX47003616 47003666 chrX 53583673 53583723 chrX 63146131 63146181 chrX72734940 72734990 chrX 76247630 76247680 chrX 76598061 76598111 chrX77344119 77344169 chrX 77681120 77681170 chrX 82449928 82449978 chrX82573468 82573518 chrX 84313364 84313414 chrX 84322641 84322691 chrX85909004 85909054 chrX 92957723 92957773 chrX 94091581 94091631 chrX99419975 99420025 chrX 100309146 100309196 chrX 100431512 100431562 chrX111596830 111596880 chr11 10232050 10232100 chrX 115246208 115246258chrX 118482309 118482359 chrX 120362724 120362774 chrX 124762385124762435 chrX 125018885 125018935 chrX 130735538 130735588 chrX133945371 133945421 chrX 133945037 133945087 chrX 134309482 134309532chr11 12235972 12236022 chrX 139222855 139222905 chrX 141311946141311996 chrX 141576135 141576185 chrX 142866165 142866215 chrX145492726 145492776 chrY 15190110 15190160 chrY 21762252 21762302 chr214982695 14982745 chr2 24121271 24121321 chr2 26469692 26469742 chr227788568 27788618 chr2 30636170 30636220 chr2 34879554 34879604 chr235057830 35057880 chr11 27840968 27841018 chr2 95013707 95013757 chr296527170 96527220 chr11 30599869 30599919 chr2 103769162 103769212 chr2104577650 104577700 chr2 105960587 105960637 chr11 31964446 31964496chr2 113394579 113394629 chr2 117429976 117430026 chr2 124804138124804188 chr2 127857596 127857646 chr2 135881211 135881261 chr2136996542 136996592 chr11 33995641 33995691 chr2 139603289 139603339chr2 141690133 141690183 chr2 170625012 170625062 chr2 188590323188590373 chr11 38767697 38767747 chr2 194846998 194847048 chr2200129822 200129872 chr11 40368467 40368517 chr11 42120354 42120404 chr2215589753 215589803 chr11 43688772 43688822 chr2 226331579 226331629chr2 232254670 232254720 chr2 236485370 236485420 chr2 242658365242658415 chr2 243290609 243290659 chr3 4684919 4684969 chr11 4700253147002581 chr3 26797675 26797725 chr3 30779548 30779598 chr3 3378137433781424 chr3 34687998 34688048 chr11 49961912 49961962 chr3 4958061349580663 chr3 49581959 49582009 chr3 50768729 50768779 chr3 5640029156400341 chr3 67131081 67131131 chr3 73209812 73209862 chr3 7975779579757845 chr3 84921649 84921699 chr3 86668620 86668670 chr3 8765507987655129 chr3 103503475 103503525 chr11 59596795 59596845 chr3 110662434110662484 chr3 111497749 111497799 chr11 60127596 60127646 chr3119431532 119431582 chr3 124826133 124826183 chr3 138911732 138911782chr3 146083846 146083896 chr3 156507106 156507156 chr3 162982713162982763 chr3 164115921 164115971 chr3 164342029 164342079 chr3164341916 164341966 chr3 164505142 164505192 chr3 167293881 167293931chr3 167849583 167849633 chr3 170380072 170380122 chr3 173610009173610059 chr3 175936327 175936377 chr3 179655695 179655745 chr3180330420 180330470 chr3 181301446 181301496 chr3 187599679 187599729chr3 192075885 192075935 chr3 197645829 197645879 chr4 8639258 8639308chr4 10237446 10237496 chr4 20093016 20093066 chr4 23560473 23560523chr4 34695621 34695671 chr4 77147238 77147288 chr4 102133275 102133325chr4 110056319 110056369 chr4 112512759 112512809 chr4 112518068112518118 chr4 116657231 116657281 chr4 123901302 123901352 chr4124132784 124132834 chr4 156341146 156341196 chr4 160004500 160004550chr4 160929009 160929059 chr4 171790517 171790567 chr4 189502026189502076 chr5 28721989 28722039 chr5 31723478 31723528 chr5 3756531737565367 chr5 41365724 41365774 chr5 43518386 43518436 chr5 5057566850575718 chr11 70145602 70145652 chr5 56220535 56220585 chr5 5818012058180170 chr5 62720865 62720915 chr5 63504070 63504120 chr5 6679936066799410 chr5 80164167 80164217 chr5 93574460 93574510 chr5 9970280599702855 chr5 104778613 104778663 chr5 109688437 109688487 chr5118620407 118620457 chr5 130822727 130822777 chr5 133149849 133149899chr5 144040757 144040807 chr5 151961785 151961835 chr5 154512279154512329 chr5 178194743 178194793 chr5 178771930 178771980 chr5179913231 179913281 chr5 180453373 180453423 chr6 13167934 13167984 chr615420709 15420759 chr10 15088803 15088853 chr6 28813592 28813642 chr630313779 30313829 chr6 30827964 30828014 chr6 31054581 31054631 chr637206577 37206627 chr6 41639559 41639609 chr6 42487923 42487973 chr678849435 78849485 chr6 79593045 79593095 chr6 81701502 81701552 chr682710600 82710650 chr6 85879054 85879104 chr6 93312200 93312250 chr6101833145 101833195 chr6 103132727 103132777 chr11 93925178 93925228chr6 111282857 111282907 chr6 113887705 113887755 chr6 114390247114390297 chr6 117793448 117793498 chr6 119352831 119352881 chr6130960654 130960704 chr6 142350076 142350126 chr11 98747850 98747900chr6 147588496 147588546 chr6 162891427 162891477 chr6 162893180162893230 chr11 104895418 104895468 chr7 648581 648631 chr7 21465132146563 chr7 2555383 2555433 chr11 108669281 108669331 chr7 78909317890981 chr7 13376499 13376549 chr7 14321680 14321730 chr7 2429106424291114 chr7 39628403 39628453 chr7 47087542 47087592 chr7 7302862573028675 chr7 78938001 78938051 chr7 80041549 80041599 chr7 8901047189010521 chr7 94810707 94810757 chr7 96828040 96828090 chr7 108340480108340530 chr7 111898941 111898991 chr11 118004117 118004167 chr7124487947 124487997 chr7 125026739 125026789 chr7 128278711 128278761chr7 131630987 131631037 chr7 145647887 145647937 chr7 154334050154334100 chr7 156011917 156011967 chr8 3531291 3531341 chr8 82039628204012 chr8 14014781 14014831 chr8 19643861 19643911 chr8 2041592820415978 chr8 23689304 23689354 chr8 28182159 28182209 chr8 5501765955017709 chr8 59601959 59602009 chr8 92669081 92669131 chr8 100904235100904285 chr8 107745747 107745797 chr8 120521578 120521628 chr1019196079 19196129 chr8 143050292 143050342 chr10 19526060 19526110 chr11130972445 130972495 chr8 146222648 146222698 chr9 4065122 4065172 chr98470826 8470876 chr9 12683319 12683369 chr9 17542337 17542387 chr922285815 22285865 chr9 22855678 22855728 chr9 25934001 25934051 chr926473423 26473473 chr9 26475580 26475630 chr9 26482072 26482122 chr930089964 30090014 chr9 32683725 32683775 chr9 34233563 34233613 chr937627054 37627104 chr9 37627280 37627330 chr9 85553088 85553138 chr992626918 92626968 chr9 109987279 109987329 chr9 109987957 109988007 chr9111756562 111756612 chr9 114733933 114733983 chr9 123931303 123931353chr9 133745564 133745614 chr12 3713765 3713815 chr12 10386936 10386986chr12 23364428 23364478 chr12 26218643 26218693 chr12 27045054 27045104chr12 30457769 30457819 chr12 40829830 40829880 chr10 26553600 26553650chr10 26684662 26684712 chr12 64810982 64811032 chr12 69671475 69671525chr12 89779197 89779247 chr12 105734164 105734214 chr12 110839619110839669 chr12 118270791 118270841 chr12 118270650 118270700 chr12118875135 118875185 chr12 119151244 119151294 chr12 119796065 119796115chr12 122521829 122521879 chr10 34005051 34005101 chr12 126747577126747627 chr10 34472928 34472978 chr12 130103030 130103080 chr1318592994 18593044 chr13 22063792 22063842 chr13 31801892 31801942 chr1339318178 39318228 chr13 43811287 43811337 chr13 48139639 48139689 chr1360702285 60702335 chr13 75704504 75704554 chr13 79863010 79863060 chr1381405630 81405680 chr13 85290690 85290740 chr13 87612605 87612655 chr1393368175 93368225 chr13 96500562 96500612 chr13 99609967 99610017 chr1418795614 18795664 chr14 18828107 18828157 chr10 45347803 45347853 chr1424465441 24465491 chr14 24995530 24995580 chr14 33386668 33386718 chr1439634501 39634551 chr14 49139244 49139294 chr14 50147499 50147549 chr1462697354 62697404 chr14 68567876 68567926 chr14 78741830 78741880 chr1482555168 82555218 chr14 86971134 86971184 chr10 54505368 54505418 chr1490279011 90279061 chr14 93943739 93943789 chr14 94308759 94308809 chr1498966281 98966331 chr10 58144743 58144793 chr14 100259728 100259778chr14 101844714 101844764 chr14 103775281 103775331 chr15 2083604220836092 chr15 25716038 25716088 chr15 31276822 31276872 chr15 3757512837575178 chr10 66195734 66195784 chr15 62779301 62779351 chr15 6380156663801616 chr15 69707299 69707349 chr15 92217667 92217717 chr16 10067691006819 chr16 5015635 5015685 chr16 5668544 5668594 chr16 1280799712808047 chr16 14620157 14620207 chr16 17386720 17386770 chr16 1738666117386711 chr16 22351730 22351780 chr16 24868735 24868785 chr16 2682151926821569 chr16 26822711 26822761 chr16 31584958 31585008 chr16 5913556459135614 chr16 60377051 60377101 chr16 60476341 60476391 chr16 6165063861650688 chr16 68539388 68539438 chr16 70029738 70029788 chr10 7441849074418540 chr16 87388740 87388790 chr16 89083325 89083375 chr17 39415603941610 chr17 4417922 4417972 chr17 4915129 4915179 chr17 53583425358392 chr17 8083468 8083518 chr17 8896882 8896932 chr17 1079301410793064 chr17 12177580 12177630 Table 15AB. Repeat Category L1MA7 chr1083209575 83209625 chr10 83210059 83210109 chr17 46649462 46649512 chr1751777550 51777600 chr18 4312645 4312695 chr18 10108922 10108972 chr1811668056 11668106 chr18 27566828 27566878 chr10 95939590 95939640 chr1831813101 31813151 chr18 32635201 32635251 chr18 46656179 46656229 chr1848530558 48530608 chr18 63934048 63934098 chr18 65696759 65696809 chr1871907355 71907405 chr18 73572363 73572413 chr19 6942096 6942146 chr197141659 7141709 chr19 9000313 9000363 chr19 9001692 9001742 chr199039972 9040022 chr19 15854112 15854162 chr19 22071291 22071341 chr1922849766 22849816 chr19 23688049 23688099 chr19 38038125 38038175 chr1938039254 38039304 chr19 39589522 39589572 chr19 41682823 41682873 chr1941862072 41862122 chr19 42962384 42962434 chr10 106170753 106170803chr19 53230284 53230334 chr10 113623780 113623830 chr19 6110356061103610 chr19 62199771 62199821 chr10 116792719 116792769 chr10116813287 116813337 chr1 22201630 22201680 chr10 120273024 120273074chr1 29013079 29013129 chr1 34475519 34475569 chr1 35060150 35060200chr1 45296971 45297021 chr1 47104738 47104788 chr1 50527762 50527812chr1 66262007 66262057 chr1 79471241 79471291 chr1 119131780 119131830chr1 149781473 149781523 chr1 171380149 171380199 chr1 187841372187841422 chr1 192221205 192221255 chr1 193550108 193550158 chr1201023797 201023847 chr1 201077789 201077839 chr10 131684610 131684660chr1 239576606 239576656 chr1 244364811 244364861 chr20 242513 242563chr10 132809618 132809668 chr20 8486434 8486484 chr20 17781090 17781140chr20 19450657 19450707 chr20 43352778 43352828 chr20 44885677 44885727chr21 15106539 15106589 chr21 27715117 27715167 chr21 28839196 28839246chr21 44208327 44208377 chr21 46825927 46825977 chr21 46825866 46825916chr22 22157976 22158026 chr22 27326915 27326965 chr22 30234033 30234083chr22 34712128 34712178 chr22 37616452 37616502 chr22 46242515 46242565chrX 13623647 13623697 chrX 13623489 13623539 chrX 14732970 14733020chrX 23046420 23046470 chrX 27276479 27276529 chrX 27277838 27277888chrX 28387997 28388047 chrX 39627461 39627511 chrX 43899101 43899151chrX 55277557 55277607 chrX 64239574 64239624 chrX 70306563 70306613chrX 71107436 71107486 chrX 71109494 71109544 chrX 72058539 72058589chrX 72910886 72910936 chrX 75477266 75477316 chrX 76143638 76143688chrX 91624098 91624148 chrX 99245274 99245324 chrX 99322824 99322874chrX 102047218 102047268 chrX 109708267 109708317 chrX 120220776120220826 chrX 126222544 126222594 chrX 128106379 128106429 chr1111752635 11752685 chrX 146622357 146622407 chrX 148641559 148641609 chrY2820953 2821003 chrY 6443553 6443603 chrY 8864325 8864375 chrY 1601970916019759 chrY 22275330 22275380 chr2 1960852 1960902 chr2 3501237735012427 chr2 39682714 39682764 chr2 48547553 48547603 chr2 5766548857665538 chr2 63468385 63468435 chr2 67086874 67086924 chr11 2494996724950017 chr2 82036248 82036298 chr11 29710195 29710245 chr2 9926462099264670 chr2 102451010 102451060 chr2 145877403 145877453 chr2148476654 148476704 chr2 160280025 160280075 chr2 170683926 170683976chr2 173341015 173341065 chr2 184306394 184306444 chr2 184402499184402549 chr2 186096695 186096745 chr2 187178594 187178644 chr2191200693 191200743 chr2 201276033 201276083 chr11 41618493 41618543chr2 221207418 221207468 chr3 4475585 4475635 chr3 11925816 11925866chr3 11925621 11925671 chr3 11930169 11930219 chr3 24592763 24592813chr3 26111616 26111666 chr3 32860390 32860440 chr3 41503896 41503946chr3 46560705 46560755 chr3 46953355 46953405 chr3 51226858 51226908chr3 51291229 51291279 chr3 87753212 87753262 chr3 130497960 130498010chr3 130958398 130958448 chr3 130958217 130958267 chr3 139566847139566897 chr3 176229362 176229412 chr3 188126441 188126491 chr3188129108 188129158 chr4 635963 636013 chr4 3323607 3323657 chr4 41421274142177 chr4 4968519 4968569 chr4 9270669 9270719 chr4 14745418 14745468chr4 14745574 14745624 chr4 31172222 31172272 chr4 37276957 37277007chr4 76859476 76859526 chr4 83336949 83336999 chr4 85555334 85555384chr4 89833227 89833277 chr4 92309832 92309882 chr4 108137125 108137175chr11 66342557 66342607 chr4 137263406 137263456 chr4 164293879164293929 chr4 184661976 184662026 chr4 184663704 184663754 chr4191339686 191339736 chr4 191339781 191339831 chr4 191340027 191340077chr4 191340267 191340317 chr5 3732704 3732754 chr5 13890872 13890922chr5 28580990 28581040 chr5 33554859 33554909 chr5 41601983 41602033chr5 57967780 57967830 chr5 81109717 81109767 chr5 87136721 87136771chr5 92040951 92041001 chr5 92042472 92042522 chr11 71308715 71308765chr5 105471321 105471371 chr5 123331168 123331218 chr5 125064102125064152 chr5 125494342 125494392 chr5 125497064 125497114 chr5130167242 130167292 chr5 134136097 134136147 chr11 73367780 73367830chr5 148392299 148392349 chr5 154391654 154391704 chr5 160412711160412761 chr5 171695755 171695805 chr5 180259665 180259715 chr5180502746 180502796 chr11 77402115 77402165 chr6 17494150 17494200 chr621409903 21409953 chr6 24142989 24143039 chr6 27609680 27609730 chr630613708 30613758 chr6 31903847 31903897 chr6 32621369 32621419 chr632670388 32670438 chr6 32670511 32670561 chr6 34278963 34279013 chr644040799 44040849 chr6 48384900 48384950 chr6 71154337 71154387 chr672350694 72350744 chr6 74477510 74477560 chr6 74494538 74494588 chr688231900 88231950 chr6 94191771 94191821 chr6 95647283 95647333 chr695654438 95654488 chr6 103305087 103305137 chr6 108683589 108683639 chr6111786902 111786952 chr6 119927959 119928009 chr6 123212321 123212371chr6 150195012 150195062 chr6 158318218 158318268 chr6 161169488161169538 chr6 161169553 161169603 chr6 161169907 161169957 chr6161438725 161438775 chr6 161439080 161439130 chr6 161439198 161439248chr6 164294186 164294236 chr6 164294328 164294378 chr6 168130458168130508 chr6 170311683 170311733 chr11 107015524 107015574 chr71556009 1556059 chr7 2653220 2653270 chr7 3979398 3979448 chr7 1323360613233656 chr7 14062802 14062852 chr7 22420423 22420473 chr7 2868830328688353 chr7 37218507 37218557 chr7 39741862 39741912 chr11 112863406112863456 chr7 55655177 55655227 chr7 55709561 55709611 chr7 6372539263725442 chr7 63725445 63725495 chr7 65802600 65802650 chr7 6795077567950825 chr7 80050425 80050475 chr7 96487577 96487627 chr7 107103857107103907 chr7 136282292 136282342 chr7 145647887 145647937 chr7151831618 151831668 chr7 155752028 155752078 chr8 834907 834957 chr82033156 2033206 chr8 5349139 5349189 chr8 6903315 6903365 chr8 69039356903985 chr8 11951100 11951150 chr8 12437456 12437506 chr8 1243668012436730 chr8 12876889 12876939 chr11 122445321 122445371 chr8 1690811216908162 chr8 17232192 17232242 chr8 38975406 38975456 chr8 5752233557522385 chr8 57521994 57522044 chr8 65836640 65836690 chr8 6659157966591629 chr8 74390950 74391000 chr8 89491775 89491825 chr8 9027939590279445 chr8 90336668 90336718 chr8 91023089 91023139 chr8 9711868797118737 chr8 97622262 97622312 chr8 99211113 99211163 chr8 103101496103101546 chr8 132336492 132336542 chr8 141300107 141300157 chr11130572650 130572700 chr9 1127264 1127314 chr9 4947610 4947660 chr96678577 6678627 chr9 9148201 9148251 chr9 15870108 15870158 chr921815308 21815358 chr9 29649846 29649896 chr9 38468265 38468315 chr966957699 66957749 chr9 72670216 72670266 chr9 84636915 84636965 chr986339384 86339434 chr9 89335347 89335397 chr9 92609153 92609203 chr993826033 93826083 chr9 94795031 94795081 chr9 94795545 94795595 chr995209693 95209743 chr9 101517914 101517964 chr9 109741047 109741097 chr9109741216 109741266 chr9 111228811 111228861 chr12 1535895 1535945 chr9127166810 127166860 chr9 127167564 127167614 chr12 2984616 2984666 chr123082145 3082195 chr12 9792713 9792763 chr12 24017923 24017973 chr1224018133 24018183 chr12 27217688 27217738 chr12 95652299 95652349 chr12100800118 100800168 chr10 30559218 30559268 chr12 113366830 113366880chr12 121478490 121478540 chr10 34408114 34408164 chr13 2098718720987237 chr13 36333253 36333303 chr13 44565163 44565213 chr13 5646178956461839 chr13 67136503 67136553 chr13 81824455 81824505 chr13 8223863282238682 chr13 104619850 104619900 chr13 111528594 111528644 chr13111869692 111869742 chr14 18670218 18670268 chr14 20032249 20032299chr14 33434071 33434121 chr14 35076050 35076100 chr14 46229206 46229256chr14 46516128 46516178 chr14 51155231 51155281 chr14 77906467 77906517chr14 86011597 86011647 chr14 97134833 97134883 chr14 102520495102520545 chr14 104819282 104819332 chr15 19266489 19266539 chr1519763976 19764026 chr15 21592628 21592678 chr15 21748934 21748984 chr1521894279 21894329 chr15 22270328 22270378 chr15 23626101 23626151 chr1530989900 30989950 chr15 38698643 38698693 chr15 50358067 50358117 chr1553169043 53169093 chr10 68976094 68976144 chr10 68976807 68976857 chr1588397088 88397138 chr15 99127361 99127411 chr16 26886043 26886093 chr1634892671 34892721 chr16 53561964 53562014 chr16 80652544 80652594 chr1687167095 87167145 chr10 75252045 75252095 chr17 2553752 2553802 chr178772966 8773016 chr17 10754150 10754200 chr17 12105194 12105244 chr1714078969 14079019 Table 15AC. Repeat Category L1PA10 chr17 5025253850252588 chr17 64117804 64117854 chr18 4079513 4079563 chr10 9441533594415385 chr18 12456556 12456606 chr18 29220905 29220955 chr18 3072661230726662 chr18 31091641 31091691 chr18 31091750 31091800 chr18 5375061053750660 chr18 54250097 54250147 chr18 61488063 61488113 chr18 6148795061488000 chr18 66585508 66585558 chr18 72470759 72470809 chr18 7302313873023188 chr19 2455985 2456035 chr19 5329739 5329789 chr19 65356386535688 chr19 15717376 15717426 chr19 15826061 15826111 chr19 1618558916185639 chr19 21017509 21017559 chr19 21710382 21710432 chr19 2238732522387375 chr19 22770247 22770297 chr19 35681603 35681653 chr19 4669898246699032 chr19 50057613 50057663 chr19 50057768 50057818 chr19 5324172453241774 chr19 56059362 56059412 chr19 59498707 59498757 chr19 5949863659498686 chr19 60223142 60223192 chr19 61561616 61561666 chr19 6266254162662591 chr19 62663313 62663363 chr1 9823107 9823157 chr10 121552460121552510 chr1 41845770 41845820 chr1 56206883 56206933 chr1 6225322062253270 chr1 69396699 69396749 chr1 91159585 91159635 chr1 152965514152965564 chr1 152965426 152965476 chr1 159651111 159651161 chr1170471915 170471965 chr1 186026359 186026409 chr1 186070465 186070515chr1 186072147 186072197 chr1 192037347 192037397 chr1 211723853211723903 chr1 236049393 236049443 chr1 238720922 238720972 chr1244274822 244274872 chr20 5309735 5309785 chr20 45008622 45008672 chr2053337013 53337063 chr20 53576552 53576602 chr20 60591086 60591136 chr2116815403 16815453 chr21 17173591 17173641 chr21 23368632 23368682 chr2126837781 26837831 chr21 29684534 29684584 chr11 435468 435518 chr2136192720 36192770 chr21 45592947 45592997 chr22 15715877 15715927 chr2222297851 22297901 chr22 25011253 25011303 chr22 25508924 25508974 chr2230865552 30865602 chr22 32741046 32741096 chr22 34908292 34908342 chr2243694077 43694127 chrX 2954666 2954716 chrX 3076500 3076550 chrX 41916024191652 chrX 7255205 7255255 chrX 20253720 20253770 chrX 3389578533895835 chrX 34630488 34630538 chrX 39883260 39883310 chrX 4412108644121136 chrX 49395823 49395873 chrX 54046144 54046194 chrX 5510748555107535 chrX 62105939 62105989 chrX 63644037 63644087 chrX 7146759171467641 chrX 76886030 76886080 chrX 81466896 81466946 chrX 8513679685136846 chrX 86727887 86727937 chrX 91523785 91523835 chrX 100694030100694080 chrX 100703245 100703295 chrX 106678951 106679001 chrX106862532 106862582 chrX 106866712 106866762 chrX 111351040 111351090chrX 121997400 121997450 chrX 126437759 126437809 chr11 1356896813569018 chrX 152357970 152358020 chrY 7125685 7125735 chr11 1532585615325906 chr2 3277555 3277605 chr2 12230618 12230668 chr2 2852851028528560 chr11 18930183 18930233 chr2 52173576 52173626 chr2 5591251455912564 chr2 57351994 57352044 chr10 11730751 11730801 chr2 6375640263756452 chr2 70668251 70668301 chr2 75925176 75925226 chr2 8396963983969689 chr2 95950686 95950736 chr2 95977329 95977379 chr2 9859952198599571 chr2 98605334 98605384 chr2 98605388 98605438 chr2 103934530103934580 chr2 136303402 136303452 chr2 137945960 137946010 chr1135433970 35434020 chr2 168877826 168877876 chr2 170895419 170895469 chr2173176591 173176641 chr2 178420623 178420673 chr2 179348838 179348888chr2 184773627 184773677 chr2 194811863 194811913 chr2 196645647196645697 chr2 224020361 224020411 chr2 231409748 231409798 chr2238467594 238467644 chr3 23061476 23061526 chr3 52948323 52948373 chr373701793 73701843 chr3 74955989 74956039 chr3 82081017 82081067 chr384219795 84219845 chr3 89845581 89845631 chr3 95717230 95717280 chr3119639148 119639198 chr3 121276915 121276965 chr3 122152164 122152214chr3 127811245 127811295 chr3 138991620 138991670 chr3 154288327154288377 chr3 159154087 159154137 chr3 159153965 159154015 chr1162632600 62632650 chr4 8849074 8849124 chr4 12544457 12544507 chr417437746 17437796 chr4 25037130 25037180 chr4 28651559 28651609 chr429386853 29386903 chr4 37360323 37360373 chr4 37358771 37358821 chr442045510 42045560 chr4 43086551 43086601 chr4 48053538 48053588 chr448053470 48053520 chr4 56419008 56419058 chr4 68842604 68842654 chr481722842 81722892 chr11 65596523 65596573 chr4 108959144 108959194 chr4129101735 129101785 chr4 129101547 129101597 chr4 133724610 133724660chr4 135139711 135139761 chr4 154403250 154403300 chr4 157071766157071816 chr4 167633948 167633998 chr4 176463337 176463387 chr4188888579 188888629 chr4 189339316 189339366 chr5 994927 994977 chr53550564 3550614 chr5 45065653 45065703 chr5 63603420 63603470 chr571655759 71655809 chr5 75231846 75231896 chr5 94129429 94129479 chr596784007 96784057 chr5 102025234 102025284 chr5 102024214 102024264 chr5117838679 117838729 chr5 130308709 130308759 chr5 142939442 142939492chr5 151789792 151789842 chr5 154733518 154733568 chr5 160231293160231343 chr5 166161133 166161183 chr5 168779892 168779942 chr5171729269 171729319 chr6 18615023 18615073 chr6 49396411 49396461 chr649817521 49817571 chr6 54921254 54921304 chr11 88532330 88532380 chr664291721 64291771 chr11 90401194 90401244 chr6 74747115 74747165 chr684191454 84191504 chr11 92557848 92557898 chr6 108390913 108390963 chr6120158951 120159001 chr11 96607504 96607554 chr6 137335810 137335860chr6 137867341 137867391 chr6 154908871 154908921 chr6 156878108156878158 chr11 104895418 104895468 chr11 105369288 105369338 chr74174729 4174779 chr7 9474833 9474883 chr7 23845278 23845328 chr738727087 38727137 chr7 49629483 49629533 chr7 70627633 70627683 chr776576139 76576189 chr7 79570788 79570838 chr7 81341103 81341153 chr790940717 90940767 chr7 96299412 96299462 chr7 109534682 109534732 chr7111747858 111747908 chr7 118415833 118415883 chr7 130099509 130099559chr7 130694642 130694692 chr7 133276883 133276933 chr7 143129491143129541 chr7 156755506 156755556 chr8 5759543 5759593 chr8 90618309061880 chr8 12021480 12021530 chr8 13993941 13993991 chr8 1907586119075911 chr8 27939134 27939184 chr8 31205423 31205473 chr8 4263849442638544 chr8 88042896 88042946 chr8 104602371 104602421 chr8 110299555110299605 chr8 111530610 111530660 chr8 118745802 118745852 chr8118976138 118976188 chr11 129068945 129068995 chr11 129067730 129067780chr8 126880020 126880070 chr8 136842059 136842109 chr8 141588892141588942 chr8 144293928 144293978 chr9 10818414 10818464 chr9 2221934722219397 chr11 132916409 132916459 chr9 28107906 28107956 chr9 7577628675776336 chr9 80136978 80137028 chr9 82198898 82198948 chr9 8581054985810599 chr9 91521400 91521450 chr9 92634124 92634174 chr9 9263471692634766 chr9 92634904 92634954 chr9 100746438 100746488 chr9 106249708106249758 chr9 111134285 111134335 chr9 118502866 118502916 chr1022192963 22193013 chr10 22203324 22203374 chr12 8571561 8571611 chr1023064880 23064930 chr12 18005478 18005528 chr12 58482225 58482275 chr1262843530 62843580 chr12 63232943 63232993 chr12 63674690 63674740 chr1279469345 79469395 chr12 92455143 92455193 chr12 92587902 92587952 chr1297324023 97324073 chr12 114737322 114737372 chr12 116532463 116532513chr10 33077282 33077332 chr13 36377542 36377592 chr13 37492442 37492492chr13 54818244 54818294 chr13 56500371 56500421 chr13 86816615 86816665chr13 88428448 88428498 chr13 89991753 89991803 chr13 101169940101169990 chr13 101842647 101842697 chr14 36907001 36907051 chr1442116706 42116756 chr14 57386257 57386307 chr14 65513765 65513815 chr1053954142 53954192 chr14 85344044 85344094 chr14 90014834 90014884 chr1061422310 61422360 chr15 25486223 25486273 chr15 27036149 27036199 chr1528743454 28743504 chr15 31586315 31586365 chr15 31585352 31585402 chr1535167266 35167316 chr15 37013914 37013964 chr15 57521773 57521823 chr1561456669 61456719 chr15 62278458 62278508 chr15 77627701 77627751 chr1594715304 94715354 chr15 94715171 94715221 chr16 6135854 6135904 chr167224649 7224699 chr16 14228681 14228731 chr16 27873816 27873866 chr1628975028 28975078 chr16 30206560 30206610 chr16 47519498 47519548 chr1661932828 61932878 chr16 62826156 62826206 chr16 67920095 67920145 chr1667922983 67923033 chr16 81218942 81218992 chr16 82404524 82404574 chr1684287665 84287715 chr16 84369434 84369484 chr16 85869268 85869318 chr1729416809 29416859 Table 15AD. Repeat Category L1PA12 chr18 4619902946199079 chr19 23272870 23272920 chr19 44807064 44807114 chr10 108291957108292007 chr10 110674802 110674852 chr19 57328505 57328555 chr10117120268 117120318 chr1 20641116 20641166 chr1 49315162 49315212 chr178301519 78301569 chr1 78301148 78301198 chr1 102545920 102545970 chr1158411184 158411234 chr1 158411565 158411615 chr1 166703864 166703914chr1 166703135 166703185 chr1 171017150 171017200 chr1 172067233172067283 chr1 187084486 187084536 chr1 187088643 187088693 chr1195050782 195050832 chr1 204666890 204666940 chr1 217483013 217483063chr1 222231440 222231490 chr1 222236615 222236665 chr20 2392494323924993 chr10 134432443 134432493 chr21 19170283 19170333 chr2123855081 23855131 chr21 34760579 34760629 chr22 27369731 27369781 chr112225128 2225178 chrX 27405708 27405758 chrX 33794689 33794739 chrX52807949 52807999 chrX 55907603 55907653 chrX 74094454 74094504 chrX77543283 77543333 chrX 81846023 81846073 chrX 86814406 86814456 chrX102102950 102103000 chrX 103391156 103391206 chrX 110400203 110400253chrX 145061491 145061541 chrY 20468938 20468988 chr2 49032613 49032663chr11 22007891 22007941 chr2 53974216 53974266 chr2 72514685 72514735chr2 95393385 95393435 chr2 95978371 95978421 chr2 95977329 95977379chr2 97729789 97729839 chr2 117881546 117881596 chr2 157773445 157773495chr3 957334 957384 chr3 3656825 3656875 chr3 33542740 33542790 chr1148415638 48415688 chr11 49145062 49145112 chr3 55232032 55232082 chr399968580 99968630 chr3 105143736 105143786 chr3 106335848 106335898 chr3117584672 117584722 chr3 120545567 120545617 chr3 141536531 141536581chr3 142233691 142233741 chr3 148189761 148189811 chr11 6289752362897573 chr3 190062049 190062099 chr4 70275199 70275249 chr4 9463249494632544 chr4 118209521 118209571 chr4 133724610 133724660 chr4145082770 145082820 chr4 172920518 172920568 chr4 190618920 190618970chr5 17706614 17706664 chr5 23756624 23756674 chr5 54998119 54998169chr5 55696299 55696349 chr5 60407963 60408013 chr5 97063991 97064041chr5 126571703 126571753 chr5 146250823 146250873 chr5 156816031156816081 chr11 86321267 86321317 chr11 86321053 86321103 chr6 6418791864187968 chr6 71054158 71054208 chr6 77236872 77236922 chr6 7933498879335038 chr6 94213910 94213960 chr6 95633808 95633858 chr6 101776325101776375 chr6 145798799 145798849 chr6 161231654 161231704 chr11110251821 110251871 chr7 62000829 62000879 chr7 96944463 96944513 chr7112200554 112200604 chr7 150703910 150703960 chr7 150703637 150703687chr7 151735665 151735715 chr8 39576240 39576290 chr8 47977137 47977187chr8 71663523 71663573 chr8 89453741 89453791 chr8 91171978 91172028chr8 116108333 116108383 chr8 118182122 118182172 chr9 12737263 12737313chr9 15345955 15346005 chr9 30290641 30290691 chr10 20554847 20554897chr12 7743841 7743891 chr12 19827970 19828020 chr12 85238799 85238849chr13 50840233 50840283 chr13 69406663 69406713 chr13 72258592 72258642chr13 85197118 85197168 chr13 87778528 87778578 chr14 19626673 19626723chr14 26723679 26723729 chr14 65125805 65125855 chr10 51598494 51598544chr15 29122117 29122167 chr15 32055613 32055663 chr15 37799915 37799965chr15 37818035 37818085 chr15 44271632 44271682 chr15 52650190 52650240chr10 74028636 74028686 chr16 84617007 84617057 Table 15AE. RepeatCategory L1PA15-16 chr18 11422702 11422752 chr19 41682823 41682873 chr174144671 74144721 chr1 105276452 105276502 chr1 155715641 155715691chr20 33447122 33447172 chr21 40506888 40506938 chr22 33354409 33354459chrX 33785012 33785062 chrX 56422241 56422291 chrX 61524868 61524918chrX 74774697 74774747 chrX 79424014 79424064 chrX 81874559 81874609chrX 86609318 86609368 chrX 87993717 87993767 chrX 141318714 141318764chrY 3193220 3193270 chr2 128115572 128115622 chr2 128117464 128117514chr2 132947303 132947353 chr2 165387330 165387380 chr2 219192377219192427 chr2 219192916 219192966 chr2 219192978 219193028 chr1149092742 49092792 chr3 138160521 138160571 chr3 197913520 197913570 chr411867802 11867852 chr4 33354901 33354951 chr10 794252 794302 chr467341126 67341176 chr10 800533 800583 chr4 81036713 81036763 chr4122861549 122861599 chr4 128968843 128968893 chr4 152376078 152376128chr5 33148491 33148541 chr5 86399411 86399461 chr5 144151334 144151384chr11 81932315 81932365 chr11 89149415 89149465 chr6 69062422 69062472chr6 77831860 77831910 chr6 83989354 83989404 chr6 93154335 93154385chr6 93724630 93724680 chr6 109959505 109959555 chr6 120244873 120244923chr7 55638059 55638109 chr7 80369034 80369084 chr7 81799084 81799134chr8 89654440 89654490 chr12 45665176 45665226 chr12 87611105 87611155chr13 23344692 23344742 chr14 24621008 24621058 chr14 40571928 40571978chr14 90217577 90217627 chr14 90218239 90218289 chr14 105144891105144941 chr15 31227724 31227774 chr15 33089198 33089248 chr15 8460807484608124 Table 15AF. Repeat Category L1PB1 chr17 43755737 43755787 chr1746001374 46001424 chr17 50660721 50660771 chr17 57191266 57191316 chr1759661102 59661152 chr17 64166439 64166489 chr17 69541296 69541346 chr1091212534 91212584 chr18 2236460 2236510 chr18 2847981 2848031 chr184682178 4682228 chr18 7324183 7324233 chr18 7336584 7336634 chr188895530 8895580 chr18 10983990 10984040 chr18 11598689 11598739 chr1812910973 12911023 chr18 13155807 13155857 chr18 13161119 13161169 chr1813566053 13566103 chr18 13566108 13566158 chr18 17548485 17548535 chr1819861327 19861377 chr18 23700432 23700482 chr18 26298451 26298501 chr1844181934 44181984 chr18 51975422 51975472 chr18 52699455 52699505 chr1852913805 52913855 chr18 57081932 57081982 chr10 98202047 98202097 chr1867578731 67578781 chr18 72799786 72799836 chr19 2075531 2075581 chr197187721 7187771 chr19 11962301 11962351 chr19 13985281 13985331 chr1914845753 14845803 chr19 15826789 15826839 chr19 15828452 15828502 chr1920573288 20573338 chr19 21325372 21325422 chr19 23331413 23331463 chr1923674870 23674920 chr19 34831840 34831890 chr19 49316765 49316815 chr1949758824 49758874 chr19 51508649 51508699 chr10 113238050 113238100chr19 61834161 61834211 chr19 61833746 61833796 chr1 5445208 5445258chr1 15666552 15666602 chr1 17731011 17731061 chr10 120719350 120719400chr1 31427906 31427956 chr1 38827855 38827905 chr1 38898322 38898372chr1 42772858 42772908 chr1 49186187 49186237 chr1 51614761 51614811chr1 51614642 51614692 chr1 53649268 53649318 chr1 57405900 57405950chr1 58324350 58324400 chr10 123533483 123533533 chr1 59149373 59149423chr1 62303635 62303685 chr1 62579861 62579911 chr1 78659185 78659235chr1 79566669 79566719 chr1 81571985 81572035 chr1 83188625 83188675chr1 86233589 86233639 chr1 86435272 86435322 chr10 6707061 6707111 chr192038421 92038471 chr1 93871275 93871325 chr1 114046013 114046063 chr1115856007 115856057 chr1 115936482 115936532 chr1 116435726 116435776chr1 116677552 116677602 chr1 144070160 144070210 chr1 144807769144807819 chr10 128018174 128018224 chr1 158032935 158032985 chr1160000209 160000259 chr1 160025795 160025845 chr1 160025945 160025995chr1 160026187 160026237 chr1 160026297 160026347 chr1 160026485160026535 chr1 163253446 163253496 chr1 170949271 170949321 chr1176884082 176884132 chr1 195688142 195688192 chr1 196262538 196262588chr1 211342635 211342685 chr1 225493194 225493244 chr1 231408349231408399 chr1 233170893 233170943 chr1 233407225 233407275 chr1233594634 233594684 chr1 234488099 234488149 chr1 235249412 235249462chr20 12748493 12748543 chr20 15676080 15676130 chr20 15676002 15676052chr20 18206219 18206269 chr20 20103164 20103214 chr20 20101860 20101910chr10 133332059 133332109 chr20 22160382 22160432 chr20 2466674424666794 chr20 52703480 52703530 chr20 58215431 58215481 chr20 5974653659746586 chr21 15891494 15891544 chr21 18189300 18189350 chr21 2821992028219970 chr21 29133737 29133787 chr21 29912214 29912264 chr21 3215209132152141 chr21 36124695 36124745 chr21 43956269 43956319 chr21 4686559446865644 chr21 46864097 46864147 chr22 14677823 14677873 chr22 1470236014702410 chr11 1347341 1347391 chr22 21114065 21114115 chr22 2352140523521455 chr22 25218413 25218463 chr22 27275106 27275156 chr22 3048872230488772 chr22 32172514 32172564 chr22 33276234 33276284 chr22 3472881034728860 chrX 2422990 2423040 chrX 8163949 8163999 chrX 8396565 8396615chrX 14514370 14514420 chrX 18601684 18601734 chrX 18601290 18601340chrX 20198245 20198295 chrX 27384656 27384706 chrX 44660816 44660866chrX 52665125 52665175 chrX 53627305 53627355 chrX 54036977 54037027chrX 55717598 55717648 chrX 61391121 61391171 chrX 64833815 64833865chrX 67357280 67357330 chrX 72723253 72723303 chrX 72729012 72729062chrX 73254840 73254890 chrX 73318379 73318429 chrX 73715385 73715435chrX 74306383 74306433 chrX 76200194 76200244 chrX 76789312 76789362chrX 89135662 89135712 chrX 89903043 89903093 chrX 90186963 90187013chrX 98349864 98349914 chrX 98630087 98630137 chrX 98783587 98783637chrX 99353498 99353548 chrX 100938954 100939004 chrX 106012830 106012880chrX 106855149 106855199 chrX 107052624 107052674 chrX 110596825110596875 chrX 113717947 113717997 chrX 113719331 113719381 chrX114023797 114023847 chrX 117979860 117979910 chrX 118731220 118731270chrX 118894812 118894862 chrX 124762385 124762435 chrX 125655802125655852 chrX 127811312 127811362 chrX 129769069 129769119 chrX135619490 135619540 chrX 135624673 135624723 chrX 136108680 136108730chrX 136252962 136253012 chrX 136841805 136841855 chrX 140505968140506018 chrX 151811316 151811366 chr11 15075443 15075493 chr2 14164881416538 chr2 6262206 6262256 chr2 26166515 26166565 chr2 2922717829227228 chr2 41762031 41762081 chr2 53869561 53869611 chr2 5527950655279556 chr2 63340913 63340963 chr2 63483809 63483859 chr2 6560166765601717 chr2 66230722 66230772 chr11 24731470 24731520 chr11 2473010024730150 chr2 68650600 68650650 chr2 69099004 69099054 chr2 7060766270607712 chr2 70610560 70610610 chr11 25678668 25678718 chr2 7573311875733168 chr2 79095235 79095285 chr2 88358557 88358607 chr2 9538111195381161 chr2 95518596 95518646 chr2 99251489 99251539 chr2 9925531199255361 chr2 112539179 112539229 chr2 113949003 113949053 chr2128898223 128898273 chr2 128904333 128904383 chr2 132521352 132521402chr2 132543365 132543415 chr2 135401904 135401954 chr2 136258392136258442 chr2 136266830 136266880 chr2 140382066 140382116 chr2149058988 149059038 chr2 156008278 156008328 chr2 158178082 158178132chr2 159026405 159026455 chr2 159148908 159148958 chr2 159203474159203524 chr2 159207973 159208023 chr2 160989569 160989619 chr2168908072 168908122 chr11 36156001 36156051 chr2 173219620 173219670chr11 39059466 39059516 chr2 196762315 196762365 chr2 205577184205577234 chr2 207099436 207099486 chr2 207651371 207651421 chr2209680011 209680061 chr2 215785885 215785935 chr2 216231881 216231931chr2 222644470 222644520 chr2 228302818 228302868 chr2 234712622234712672 chr2 236267806 236267856 chr3 2833604 2833654 chr3 1933963119339681 chr3 19871507 19871557 chr3 20937962 20938012 chr3 2716979827169848 chr3 28417759 28417809 chr11 48409596 48409646 chr3 4470033944700389 chr3 45376323 45376373 chr3 50785237 50785287 chr11 5569547455695524 chr11 55695159 55695209 chr3 59008740 59008790 chr3 7285099072851040 chr3 75034946 75034996 chr3 75037648 75037698 chr3 9909188799091937 chr3 99515231 99515281 chr3 115310082 115310132 chr3 119611698119611748 chr3 120084847 120084897 chr3 123489659 123489709 chr3126843500 126843550 chr3 132675941 132675991 chr3 139592863 139592913chr3 143759607 143759657 chr3 148672969 148673019 chr3 152324205152324255 chr3 156760801 156760851 chr3 159535650 159535700 chr3159538919 159538969 chr3 177865952 177866002 chr3 177929670 177929720chr3 191276997 191277047 chr3 197228609 197228659 chr4 9324336 9324386chr4 14084717 14084767 chr4 14232860 14232910 chr4 22227934 22227984chr4 39258041 39258091 chr4 42691070 42691120 chr4 45345615 45345665chr4 54873676 54873726 chr4 67692210 67692260 chr4 71326740 71326790chr4 81156810 81156860 chr4 82793544 82793594 chr4 87897280 87897330chr4 102763344 102763394 chr4 103865331 103865381 chr4 104117335104117385 chr4 106189552 106189602 chr4 115521050 115521100 chr4116579222 116579272 chr4 122358442 122358492 chr4 124107099 124107149chr4 124166475 124166525 chr4 129239899 129239949 chr4 129505411129505461 chr4 133778329 133778379 chr4 145181923 145181973 chr4147178271 147178321 chr4 153229381 153229431 chr4 154340329 154340379chr4 163788117 163788167 chr4 163897128 163897178 chr4 172596714172596764 chr4 175389140 175389190 chr4 187999230 187999280 chr4189288590 189288640 chr4 189547165 189547215 chr4 189936423 189936473chr4 189936703 189936753 chr4 189939739 189939789 chr4 190390211190390261 chr4 190393381 190393431 chr4 190739029 190739079 chr5 98557699855819 chr5 17050133 17050183 chr5 17706614 17706664 chr5 2258027322580323 chr5 25413578 25413628 chr5 29693226 29693276 chr10 1401302714013077 chr5 35792089 35792139 chr5 35791614 35791664 chr5 3805219838052248 chr5 54880452 54880502 chr5 57464141 57464191 chr5 5996854359968593 chr5 67067716 67067766 chr5 76925310 76925360 chr5 8134011081340160 chr5 81396870 81396920 chr5 93178193 93178243 chr5 9823204098232090 chr5 98295344 98295394 chr5 103475119 103475169 chr5 108647406108647456 chr5 111926933 111926983 chr5 114562310 114562360 chr1171992986 71993036 chr5 124174921 124174971 chr5 133033910 133033960 chr5135857659 135857709 chr5 135863809 135863859 chr5 143224210 143224260chr5 145023685 145023735 chr5 145297332 145297382 chr11 7355547973555529 chr5 161760151 161760201 chr5 169869670 169869720 chr5174081126 174081176 chr5 175913778 175913828 chr6 4543460 4543510 chr64783093 4783143 chr11 78568832 78568882 chr6 28032241 28032291 chr628555101 28555151 chr6 29036152 29036202 chr6 29039151 29039201 chr629145861 29145911 chr6 30545563 30545613 chr6 30558998 30559048 chr632309993 32310043 chr6 33111365 33111415 chr6 42509159 42509209 chr644970396 44970446 chr6 45311537 45311587 chr6 45707305 45707355 chr646795022 46795072 chr6 47637383 47637433 chr6 56804762 56804812 chr664534791 64534841 chr6 65413514 65413564 chr11 90906773 90906823 chr685040591 85040641 chr6 87376520 87376570 chr6 91584694 91584744 chr6102237346 102237396 chr11 94421798 94421848 chr6 111602739 111602789chr6 117381576 117381626 chr6 117739390 117739440 chr6 119793243119793293 chr6 119792990 119793040 chr6 126670584 126670634 chr1196997256 96997306 chr6 134509904 134509954 chr6 135666863 135666913 chr6138358435 138358485 chr11 97960274 97960324 chr6 143947052 143947102chr6 148304728 148304778 chr11 100061137 100061187 chr6 152001290152001340 chr6 155689744 155689794 chr6 160451934 160451984 chr6167394090 167394140 chr6 169529605 169529655 chr6 169529697 169529747chr11 107168599 107168649 chr11 107182177 107182227 chr11 107538184107538234 chr7 4169290 4169340 chr7 4896093 4896143 chr11 108986376108986426 chr7 6811043 6811093 chr7 11293871 11293921 chr7 1781958817819638 chr7 25811936 25811986 chr7 35464247 35464297 chr7 3692117436921224 chr7 37060033 37060083 chr7 41081366 41081416 chr7 4221521642215266 chr11 112894632 112894682 chr7 46889747 46889797 chr7 4770197347702023 chr7 55917478 55917528 chr7 63661619 63661669 chr7 6371713863717188 chr7 67250919 67250969 chr7 76005825 76005875 chr7 8061586980615919 chr7 86984141 86984191 chr7 89676151 89676201 chr7 9077544990775499 chr7 94109542 94109592 chr7 94418375 94418425 chr7 9441778194417831 chr7 96315498 96315548 chr7 96343547 96343597 chr11 117598984117599034 chr11 117733877 117733927 chr7 108973647 108973697 chr7116301055 116301105 chr7 120006665 120006715 chr7 122827023 122827073chr7 123040070 123040120 chr7 125377973 125378023 chr11 118183527118183577 chr7 132439665 132439715 chr7 138006195 138006245 chr7138006019 138006069 chr7 138941922 138941972 chr7 140128601 140128651chr7 144315895 144315945 chr7 146992429 146992479 chr7 148223992148224042 chr7 151779333 151779383 chr11 120624272 120624322 chr83850282 3850332 chr8 4004287 4004337 chr8 4385082 4385132 chr8 1243140512431455 chr8 12488148 12488198 chr8 14300477 14300527 chr8 1772101617721066 chr8 30767563 30767613 chr8 37602685 37602735 chr8 3846955238469602 chr8 39249213 39249263 chr8 40482302 40482352 chr8 5303371853033768 chr8 61118250 61118300 chr8 62332846 62332896 chr8 7008430170084351 chr8 81698805 81698855 chr8 82389086 82389136 chr8 8576912785769177 chr8 90436847 90436897 chr11 127248997 127249047 chr8 9846909298469142 chr8 98955033 98955083 chr8 110267524 110267574 chr8 110280018110280068 chr8 112562538 112562588 chr8 116011722 116011772 chr8118544862 118544912 chr8 118971229 118971279 chr11 129173272 129173322chr11 129210517 129210567 chr8 136232812 136232862 chr8 142181817142181867 chr9 4638385 4638435 chr9 5533223 5533273 chr9 6306634 6306684chr9 12097039 12097089 chr9 15404397 15404447 chr9 20251522 20251572chr9 21835345 21835395 chr9 24981607 24981657 chr9 26417981 26418031chr9 27411019 27411069 chr9 31121206 31121256 chr9 33337370 33337420chr9 34203518 34203568 chr9 35042210 35042260 chr9 38011027 38011077chr9 81680958 81681008 chr9 85597157 85597207 chr10 20663720 20663770chr9 90658650 90658700 chr9 90662332 90662382 chr9 96879206 96879256chr9 97170774 97170824 chr9 104148264 104148314 chr9 106374455 106374505chr9 110492024 110492074 chr9 116015475 116015525 chr12 1123819 1123869chr9 129305795 129305845 chr9 136050246 136050296 chr12 5535567 5535617chr12 8396205 8396255 chr12 10757152 10757202 chr12 10757048 10757098chr12 15920356 15920406 chr12 19819663 19819713 chr12 29688948 29688998chr12 38626887 38626937 chr12 38677964 38678014 chr12 44201829 44201879chr10 25814368 25814418 chr12 48294859 48294909 chr12 49552247 49552297chr12 50287660 50287710 chr10 26882533 26882583 chr10 26941800 26941850chr10 27229406 27229456 chr12 55954722 55954772 chr12 56640809 56640859chr12 56640103 56640153 chr12 67731903 67731953 chr12 73436589 73436639chr12 75628125 75628175 chr12 75633574 75633624 chr12 76227516 76227566chr12 81967751 81967801 chr12 87191902 87191952 chr12 91209699 91209749chr12 91219318 91219368 chr12 98749826 98749876 chr12 103685990103686040 chr12 111185097 111185147 chr12 114757353 114757403 chr12115609705 115609755 chr12 115614175 115614225 chr12 118295263 118295313chr12 121295132 121295182 chr10 33452095 33452145 chr12 125816420125816470 chr12 125839614 125839664 chr12 126703409 126703459 chr1319539585 19539635 chr13 20234551 20234601 chr10 36415680 36415730 chr1325346667 25346717 chr10 36957945 36957995 chr13 30492540 30492590 chr1343618657 43618707 chr13 45714995 45715045 chr13 46293582 46293632 chr1350044511 50044561 chr13 62943365 62943415 chr13 63433129 63433179 chr1363434625 63434675 chr13 68069865 68069915 chr13 82764219 82764269 chr1383644821 83644871 chr13 85351454 85351504 chr13 85911036 85911086 chr1388282518 88282568 chr13 90641224 90641274 chr13 90648299 90648349 chr1396345693 96345743 chr13 98538648 98538698 chr13 100892110 100892160chr13 106000597 106000647 chr13 111007495 111007545 chr13 111988753111988803 chr14 18343219 18343269 chr14 21662333 21662383 chr14 2196046121960511 chr14 23670760 23670810 chr14 27035994 27036044 chr10 4703262847032678 chr14 40581301 40581351 chr14 54905407 54905457 chr14 5690872056908770 chr14 58364946 58364996 chr14 61527384 61527434 chr14 6179556361795613 chr14 66379074 66379124 chr14 92909280 92909330 chr14 9723424697234296 chr14 99333394 99333444 chr10 58359349 58359399 chr14 100632926100632976 chr14 102204340 102204390 chr14 104926463 104926513 chr1521598705 21598755 chr15 25973539 25973589 chr15 29618531 29618581 chr1529677714 29677764 chr15 30899447 30899497 chr10 63625136 63625186 chr1543823338 43823388 chr15 48182218 48182268 chr15 53464704 53464754 chr1553468239 53468289 chr15 53571562 53571612 chr15 59436840 59436890 chr1066083679 66083729 chr10 66569482 66569532 chr15 65451859 65451909 chr1068333934 68333984 chr15 70492597 70492647 chr15 71230940 71230990 chr1590955162 90955212 chr15 97764461 97764511 chr15 99306726 99306776 chr1599867416 99867466 chr16 5089906 5089956 chr16 5325975 5326025 chr1071127189 71127239 chr16 9429169 9429219 chr16 10469693 10469743 chr1617608301 17608351 chr16 58112778 58112828 chr16 61161423 61161473 chr1670720060 70720110 chr16 71409891 71409941 chr16 75495898 75495948 chr1675641486 75641536 chr16 81236619 81236669 chr16 84245192 84245242 chr1686555580 86555630 chr17 3482778 3482828 chr17 25569914 25569964 chr1081547378 81547428 Table 15AG. Repeat Category L1PB4 chr17 3858190338581953 chr17 59444388 59444438 chr17 79523759 79523809 chr18 51232795123329 chr18 5123109 5123159 chr18 6021888 6021938 chr18 80534528053502 chr18 8716666 8716716 chr18 12398727 12398777 chr18 1323235413232404 chr18 19253945 19253995 chr18 46759150 46759200 chr18 4842868248428732 chr18 51382497 51382547 chr18 51428880 51428930 chr19 22103702210420 chr19 6250321 6250371 chr19 9001692 9001742 chr19 1707136017071410 chr19 21046143 21046193 chr19 37364866 37364916 chr19 4772858047728630 chr19 50058264 50058314 chr19 50058545 50058595 chr19 5067476350674813 chr19 56099169 56099219 chr19 62594913 62594963 chr10 117933757117933807 chr1 21377715 21377765 chr1 34472468 34472518 chr1 4295468142954731 chr1 49807896 49807946 chr1 52529338 52529388 chr1 6024100660241056 chr1 88844852 88844902 chr1 110909691 110909741 chr1 114989101114989151 chr10 128063981 128064031 chr1 156708152 156708202 chr1157988499 157988549 chr1 187209369 187209419 chr1 190258438 190258488chr1 190259855 190259905 chr1 191357550 191357600 chr1 193738662193738712 chr10 129923309 129923359 chr1 207244589 207244639 chr1218286845 218286895 chr1 224355671 224355721 chr1 226871287 226871337chr1 228043173 228043223 chr1 244588804 244588854 chr1 244917095244917145 chr10 132663538 132663588 chr20 10890743 10890793 chr2018318790 18318840 chr20 18424532 18424582 chr20 44832844 44832894 chr2053139999 53140049 chr20 61691421 61691471 chr21 18015648 18015698 chr2142659867 42659917 chr21 42659758 42659808 chrX 3178226 3178276 chrX18474015 18474065 chrX 18473733 18473783 chrX 23014562 23014612 chrX32376662 32376712 chrX 37375718 37375768 chrX 40385785 40385835 chrX46088912 46088962 chrX 46308210 46308260 chrX 47597451 47597501 chrX53107455 53107505 chrX 53696224 53696274 chrX 94354445 94354495 chrX95467954 95468004 chrX 98893479 98893529 chrX 105423659 105423709 chr119951015 9951065 chrX 119456614 119456664 chrX 124153327 124153377 chrX134910153 134910203 chrX 139236111 139236161 chrX 151771128 151771178chrY 17492112 17492162 chr2 644195 644245 chr2 643851 643901 chr22757802 2757852 chr2 14120165 14120215 chr2 14540219 14540269 chr231199513 31199563 chr2 33567398 33567448 chr11 21508460 21508510 chr252783190 52783240 chr11 25518476 25518526 chr2 109621520 109621570 chr2109621392 109621442 chr2 133099963 133100013 chr2 133802550 133802600chr2 158692205 158692255 chr2 182557052 182557102 chr2 184772276184772326 chr2 194748838 194748888 chr11 41477614 41477664 chr3 28160722816122 chr3 11049480 11049530 chr10 12392856 12392906 chr3 3415053834150588 chr3 46056514 46056564 chr3 58488560 58488610 chr3 6041530760415357 chr3 82186034 82186084 chr3 83263423 83263473 chr10 1264736612647416 chr3 95072939 95072989 chr3 123416540 123416590 chr3 163945018163945068 chr3 164801229 164801279 chr3 169182658 169182708 chr3174320387 174320437 chr3 175559957 175560007 chr3 175666880 175666930chr3 178049699 178049749 chr3 197669612 197669662 chr4 5872630 5872680chr4 17015719 17015769 chr4 25058244 25058294 chr4 25189586 25189636chr4 43912913 43912963 chr4 48717693 48717743 chr4 63012330 63012380chr4 75713557 75713607 chr4 77431894 77431944 chr4 94280544 94280594chr4 103703408 103703458 chr4 108453105 108453155 chr4 108454526108454576 chr4 109394444 109394494 chr4 109394390 109394440 chr4110919510 110919560 chr4 114339366 114339416 chr4 115231995 115232045chr4 120251875 120251925 chr4 121741119 121741169 chr4 127793709127793759 chr4 143055189 143055239 chr4 163248618 163248668 chr4187854494 187854544 chr4 189190536 189190586 chr4 191654000 191654050chr5 841636 841686 chr5 14691226 14691276 chr5 25880446 25880496 chr528409845 28409895 chr5 32034534 32034584 chr5 40743327 40743377 chr540959554 40959604 chr5 54535046 54535096 chr5 79582624 79582674 chr5100498637 100498687 chr5 100543869 100543919 chr5 115513112 115513162chr5 117849419 117849469 chr5 126149928 126149978 chr5 137045887137045937 chr5 161217176 161217226 chr5 163072100 163072150 chr5168308824 168308874 chr5 168768166 168768216 chr5 180314715 180314765chr6 1249750 1249800 chr6 3334186 3334236 chr6 8828684 8828734 chr617739865 17739915 chr6 17946554 17946604 chr11 79241342 79241392 chr624183549 24183599 chr6 27947165 27947215 chr6 35880783 35880833 chr1185874704 85874754 chr11 85874432 85874482 chr6 42962299 42962349 chr650657432 50657482 chr6 73666963 73667013 chr6 74417285 74417335 chr676624564 76624614 chr6 86756166 86756216 chr6 105514483 105514533 chr6106406218 106406268 chr6 109954469 109954519 chr6 138777209 138777259chr6 144228786 144228836 chr6 144232370 144232420 chr6 152076156152076206 chr6 165999239 165999289 chr6 169465958 169466008 chr11106770183 106770233 chr7 576986 577036 chr7 4385792 4385842 chr7 78232177823267 chr7 20372730 20372780 chr7 20372671 20372721 chr7 4436804644368096 chr7 46828289 46828339 chr7 50448810 50448860 chr7 5307122953071279 chr7 73127355 73127405 chr7 80364532 80364582 chr7 8178303381783083 chr7 86330017 86330067 chr7 87838574 87838624 chr7 8917956689179616 chr7 89667774 89667824 chr7 97512378 97512428 chr7 100648877100648927 chr7 114696302 114696352 chr7 123144509 123144559 chr11118801906 118801956 chr7 151976734 151976784 chr7 157205799 157205849chr8 287326 287376 chr8 1188363 1188413 chr8 6625266 6625316 chr11121975793 121975843 chr8 9181930 9181980 chr8 16644864 16644914 chr830072051 30072101 chr8 30578547 30578597 chr8 31690666 31690716 chr841603520 41603570 chr8 42660344 42660394 chr8 43097624 43097674 chr850825907 50825957 chr8 60897970 60898020 chr8 89654440 89654490 chr893003796 93003846 chr8 93408761 93408811 chr8 103573744 103573794 chr8122662930 122662980 chr8 126521512 126521562 chr8 141657731 141657781chr9 4810019 4810069 chr9 10354281 10354331 chr9 15653889 15653939 chr921607256 21607306 chr9 22221116 22221166 chr9 70360314 70360364 chr972805129 72805179 chr9 74881363 74881413 chr9 86216046 86216096 chr991042555 91042605 chr9 98460886 98460936 chr9 108500284 108500334 chr9110906105 110906155 chr10 21610057 21610107 chr9 130204370 130204420chr12 6183956 6184006 chr12 6183449 6183499 chr12 6403148 6403198 chr1210923227 10923277 chr12 11281871 11281921 chr12 11611573 11611623 chr1215583648 15583698 chr12 43441639 43441689 chr12 48704535 48704585 chr1254020468 54020518 chr10 27941492 27941542 chr12 68534826 68534876 chr1028709304 28709354 chr12 72992702 72992752 chr12 78987552 78987602 chr1280715804 80715854 chr10 29328022 29328072 chr10 29327879 29327929 chr1285160720 85160770 chr12 104725158 104725208 chr10 31500531 31500581chr12 121508468 121508518 chr12 123410454 123410504 chr12 123412669123412719 chr12 126625317 126625367 chr12 127923689 127923739 chr1035223269 35223319 chr12 130984052 130984102 chr12 131515297 131515347chr12 131994853 131994903 chr13 40596009 40596059 chr13 4623701546237065 chr13 54027032 54027082 chr13 72714829 72714879 chr13 8113224581132295 chr13 102859181 102859231 chr13 112688873 112688923 chr1427958240 27958290 chr10 47852635 47852685 chr14 41397411 41397461 chr1451819816 51819866 chr14 60403169 60403219 chr14 80792408 80792458 chr1482886135 82886185 chr10 54460542 54460592 chr14 90595430 90595480 chr1499571949 99571999 chr15 21211794 21211844 chr15 33581629 33581679 chr1535435131 35435181 chr15 42251400 42251450 chr15 52913382 52913432 chr1553211959 53212009 chr15 68634766 68634816 chr15 87806034 87806084 chr1591821777 91821827 chr15 92402497 92402547 chr16 2913096 2913146 chr1617453812 17453862 chr16 19983582 19983632 chr16 20176074 20176124 chr1627321563 27321613 chr16 31622793 31622843 chr16 31886326 31886376 chr1658473192 58473242 chr16 68629764 68629814 chr16 83165738 83165788 chr1688421930 88421980 chr17 9470551 9470601 chr17 12049626 12049676 chr1720978594 20978644 chr17 29485880 29485930 Table 15AH. Repeat CategoryL1PBa1 chr18 52702152 52702202 chr1 212053833 212053883 chr1 242674122242674172 chr20 55578370 55578420 chr22 22683906 22683956 chrX 3968488439684934 chrX 41540414 41540464 chrX 73341126 73341176 chrX 7616941676169466 chrX 120066320 120066370 chrX 141101318 141101368 chr2 8371961783719667 chr2 129971588 129971638 chr2 140255001 140255051 chr1136163651 36163701 chr11 36163483 36163533 chr4 9161394 9161444 chr469438269 69438319 chr4 78247579 78247629 chr4 155359931 155359981 chr4169513106 169513156 chr4 184594709 184594759 chr4 189979861 189979911chr4 189979591 189979641 chr5 53150156 53150206 chr5 56411882 56411932chr11 71280157 71280207 chr6 104228705 104228755 chr6 115049679115049729 chr6 166458144 166458194 chr7 156082285 156082335 chr7156083947 156083997 chr11 121963934 121963984 chr8 122986543 122986593chr8 122987406 122987456 chr9 29750824 29750874 chr9 102868749 102868799chr12 15918590 15918640 chr12 17198287 17198337 chr12 19819663 19819713chr12 20136289 20136339 chr12 31070458 31070508 chr10 38912633 38912683chr14 65174788 65174838 chr15 33365732 33365782 chr15 68737773 68737823chr17 6957302 6957352 chr17 11067285 11067335 Table 15AI. RepeatCategory LTR10B chr17 75761332 75761382 chr17 75767813 75767863 chr1842702251 42702301 chr18 42709465 42709515 chr19 11786268 11786318 chr1911787190 11787240 chr19 11787333 11787383 chr19 19838683 19838733 chr1919873351 19873401 chr19 19873136 19873186 chr19 20050616 20050666 chr1920050315 20050365 chr19 20140106 20140156 chr19 20547126 20547176 chr1920635101 20635151 chr19 20635493 20635543 chr19 23546170 23546220 chr13257777 3257827 chr1 96839370 96839420 chr1 238141441 238141491 chr201443812 1443862 chr20 48584794 48584844 chr20 48588906 48588956 chr2048588684 48588734 chr2 27362976 27363026 chr3 11267068 11267118 chr3121529902 121529952 chr3 177972676 177972726 chr6 27255487 27255537 chr627949213 27949263 chr6 35581077 35581127 chr6 118945482 118945532 chr7137289407 137289457 chr8 15968483 15968533 chr9 131183772 131183822 chr9131189678 131189728 chr12 17127233 17127283 chr15 78011415 78011465chr16 30145781 30145831 chr16 30146412 30146462 chr16 30147966 30148016chr16 30150310 30150360 chr16 71874243 71874293 Table 15AJ. RepeatCategory LTR10B1 chr17 75761332 75761382 chr17 75767813 75767863 chr1842702251 42702301 chr18 42709465 42709515 chr19 11786268 11786318 chr1911787190 11787240 chr19 11787333 11787383 chr19 19838683 19838733 chr1919873351 19873401 chr19 19873136 19873186 chr19 20050616 20050666 chr1920050315 20050365 chr19 20140106 20140156 chr19 20547126 20547176 chr1920635101 20635151 chr19 20635493 20635543 chr19 23546170 23546220 chr13257777 3257827 chr1 238141441 238141491 chr20 48584794 48584844 chr2048588906 48588956 chr20 48588684 48588734 chr2 27362976 27363026 chr311267068 11267118 chr3 121529902 121529952 chr6 27255487 27255537 chr627949213 27949263 chr6 118945482 118945532 chr7 137289407 137289457chr12 17127233 17127283 chr15 78011415 78011465 chr16 30145781 30145831chr16 30146412 30146462 chr16 30147966 30148016 chr16 30150310 30150360Table 15AK. Repeat Category LTR14 chr10 82134312 82134362 chr17 5151364751513697 chr10 88445843 88445893 chr17 73616199 73616249 chr17 7362341073623460 chr17 80813179 80813229 chr18 5237408 5237458 chr18 2587624225876292 chr10 98211645 98211695 chr18 75693206 75693256 chr19 77627307762780 chr19 7772243 7772293 chr19 21070381 21070431 chr19 2385127023851320 chr19 24145792 24145842 chr19 41819158 41819208 chr19 4224764942247699 chr19 43521410 43521460 chr19 43521721 43521771 chr19 5642624756426297 chr19 57661067 57661117 chr19 63107915 63107965 chr1 1700943917009489 chr1 62014127 62014177 chr1 75242614 75242664 chr1 152885526152885576 chr1 192979207 192979257 chr1 192980939 192980989 chr1222953314 222953364 chr1 222962980 222963030 chr20 2784928 2784978 chr2143974691 43974741 chr21 44015635 44015685 chr22 29396210 29396260 chr2229400220 29400270 chr22 39367811 39367861 chr22 43861367 43861417 chr2243861504 43861554 chrX 10413820 10413870 chr11 6998874 6998924 chrX72745716 72745766 chrX 81092602 81092652 chrX 99210080 99210130 chrX116188297 116188347 chrX 152294009 152294059 chrY 7697268 7697318 chrY20224249 20224299 chrY 22458742 22458792 chrY 22458853 22458903 chr1124215940 24215990 chr2 82225138 82225188 chr2 97979228 97979278 chr298203135 98203185 chr2 125877021 125877071 chr2 139829274 139829324 chr2164144919 164144969 chr2 181124049 181124099 chr2 181128659 181128709chr2 193555207 193555257 chr11 41151076 41151126 chr2 211293321211293371 chr2 228806829 228806879 chr3 58667893 58667943 chr3 8129997181300021 chr3 129868624 129868674 chr3 129960517 129960567 chr3161283877 161283927 chr3 173758124 173758174 chr11 62854917 62854967chr4 1673290 1673340 chr4 8636228 8636278 chr4 84945480 84945530 chr4167773271 167773321 chr4 182747168 182747218 chr5 23733108 23733158 chr524353855 24353905 chr5 24796617 24796667 chr5 31439340 31439390 chr531444280 31444330 chr5 141497348 141497398 chr5 178214377 178214427 chr5178283380 178283430 chr5 178449849 178449899 chr6 27263871 27263921 chr632062308 32062358 chr6 48888931 48888981 chr11 87323330 87323380 chr679559788 79559838 chr6 83003392 83003442 chr6 108357622 108357672 chr6166668349 166668399 chr6 169241030 169241080 chr7 8801179 8801229 chr714294040 14294090 chr7 47985412 47985462 chr7 82505201 82505251 chr7108824900 108824950 chr11 120645173 120645223 chr11 120689921 120689971chr8 42964621 42964671 chr9 22221116 22221166 chr9 28049344 28049394chr9 29649846 29649896 chr9 29770178 29770228 chr9 34529880 34529930chr9 99269305 99269355 chr9 118635803 118635853 chr12 10180831 10180881chr12 17516688 17516738 chr12 36824555 36824605 chr12 45585167 45585217chr12 47191786 47191836 chr12 47191649 47191699 chr13 36691902 36691952chr13 63081280 63081330 chr13 91390124 91390174 chr13 111180394111180444 chr14 46470996 46471046 chr14 78163281 78163331 chr15 4324272043242770 chr15 56122109 56122159 chr15 76630404 76630454 chr16 2069448920694539 chr16 63569578 63569628 chr10 74766673 74766723 chr17 81609818161031 chr17 8160859 8160909 Table 15AL. Repeat Category LTR14B chr1780813179 80813229 chr18 5237408 5237458 chr18 25876242 25876292 chr1921070381 21070431 chr19 24145792 24145842 chr19 42247649 42247699 chr1943521410 43521460 chr19 43521721 43521771 chr19 56426247 56426297 chr1963107915 63107965 chr1 222953314 222953364 chr1 222962980 222963030chr22 39367811 39367861 chr11 6998874 6998924 chrX 72745716 72745766chrX 152294009 152294059 chr11 24215940 24215990 chr2 97979228 97979278chr2 164144919 164144969 chr2 181124049 181124099 chr2 181128659181128709 chr11 41151076 41151126 chr2 211293321 211293371 chr2228806829 228806879 chr3 129960517 129960567 chr3 161283877 161283927chr3 173758124 173758174 chr4 182747168 182747218 chr5 23733108 23733158chr5 24796617 24796667 chr5 31439340 31439390 chr5 31444280 31444330chr5 178214377 178214427 chr5 178283380 178283430 chr5 178449849178449899 chr6 79559788 79559838 chr6 166668349 166668399 chr7 88011798801229 chr7 82505201 82505251 chr7 108824900 108824950 chr11 120645173120645223 chr11 120689921 120689971 chr9 22221116 22221166 chr9 2804934428049394 chr9 29649846 29649896 chr9 29770178 29770228 chr9 9926930599269355 chr9 118635803 118635853 chr12 10180831 10180881 chr12 1751668817516738 chr12 45585167 45585217 chr12 47191786 47191836 chr12 4719164947191699 chr13 63081280 63081330 chr13 91390124 91390174 chr13 111180394111180444 chr15 56122109 56122159 chr15 76630404 76630454 chr16 2069448920694539 Table 15AM. Repeat Category LTR14C chr17 51513647 51513697chr19 7762730 7762780 chr19 7772243 7772293 chr1 192979207 192979257chr1 192980939 192980989 chr20 2784928 2784978 chrX 10413820 10413870chrY 7697268 7697318 chrY 20224249 20224299 chrY 22458742 22458792 chrY22458853 22458903 chr2 82225138 82225188 chr2 98203135 98203185 chr2125877021 125877071 chr2 139829274 139829324 chr2 193555207 193555257chr3 81299971 81300021 chr4 84945480 84945530 chr4 167773271 167773321chr6 48888931 48888981 chr6 83003392 83003442 chr6 169241030 169241080chr7 14294040 14294090 chr7 47985412 47985462 chr8 42964621 42964671chr12 36824555 36824605 chr13 36691902 36691952 chr14 46470996 46471046chr15 43242720 43242770 chr16 63569578 63569628 Table 15AN. RepeatCategory LTR17 chr17 45658618 45658668 chr10 83255290 83255340 chr1748951322 48951372 chr17 53570257 53570307 chr10 85949723 85949773 chr1085989986 85990036 chr10 88036489 88036539 chr17 69170841 69170891 chr1771231705 71231755 chr18 4682178 4682228 chr18 25231092 25231142 chr1835191349 35191399 chr18 41996588 41996638 chr18 50165618 50165668 chr1853551447 53551497 chr10 98714916 98714966 chr18 71777429 71777479 chr1920072902 20072952 chr19 43872618 43872668 chr19 43872736 43872786 chr1943873380 43873430 chr19 45166413 45166463 chr19 59627585 59627635 chr10120023871 120023921 chr1 54746573 54746623 chr1 54754695 54754745 chr155619664 55619714 chr1 66983805 66983855 chr1 68227690 68227740 chr168227945 68227995 chr1 80480933 80480983 chr1 83627454 83627504 chr188857722 88857772 chr1 119071816 119071866 chr1 175020867 175020917 chr1175350090 175350140 chr1 204033835 204033885 chr1 204998449 204998499chr1 218781096 218781146 chr1 224787299 224787349 chr1 226039857226039907 chr20 25567242 25567292 chr20 38012756 38012806 chr20 4090031440900364 chr21 19053961 19054011 chr21 19971628 19971678 chr21 2034286520342915 chr21 22654305 22654355 chr21 25412957 25413007 chr21 2714932027149370 chr21 40038137 40038187 chr21 40038539 40038589 chr21 4171556241715612 chr22 27482081 27482131 chr22 32578459 32578509 chrX 70828067082856 chrX 20351787 20351837 chrX 26135420 26135470 chrX 2770060727700657 chrX 27702543 27702593 chrX 67534924 67534974 chrX 7030004770300097 chr11 9083663 9083713 chrX 87761833 87761883 chrX 8897873988978789 chrX 92008451 92008501 chrX 101123629 101123679 chrX 101142058101142108 chrX 103663052 103663102 chrX 105066921 105066971 chrX111554428 111554478 chrX 111903857 111903907 chrX 117197325 117197375chrX 119188270 119188320 chrX 125655802 125655852 chrX 130259762130259812 chrX 135701274 135701324 chrX 144770216 144770266 chrX146693725 146693775 chrY 4098322 4098372 chrY 14925140 14925190 chr2150370 150420 chr2 17505085 17505135 chr2 26455967 26456017 chr230466759 30466809 chr2 30713843 30713893 chr2 30717341 30717391 chr231482499 31482549 chr2 33857360 33857410 chr2 34932350 34932400 chr243033625 43033675 chr2 53958434 53958484 chr11 22303684 22303734 chr258477538 58477588 chr11 23250755 23250805 chr11 23427094 23427144 chr1125952001 25952051 chr11 26576805 26576855 chr11 26582972 26583022 chr276073721 76073771 chr2 78748363 78748413 chr2 81073326 81073376 chr296367996 96368046 chr2 106453087 106453137 chr2 112897177 112897227 chr2139241831 139241881 chr2 166027869 166027919 chr2 172618972 172619022chr11 36311198 36311248 chr2 183620343 183620393 chr11 38489858 38489908chr2 189251849 189251899 chr2 196407284 196407334 chr2 207007232207007282 chr2 210373857 210373907 chr2 239709445 239709495 chr319892375 19892425 chr3 38291516 38291566 chr3 38298973 38299023 chr343487872 43487922 chr3 48338101 48338151 chr3 58382900 58382950 chr370599576 70599626 chr3 70600051 70600101 chr3 75609014 75609064 chr378314305 78314355 chr3 83485658 83485708 chr3 86382005 86382055 chr387915848 87915898 chr3 88856901 88856951 chr3 95004507 95004557 chr3103772202 103772252 chr3 107006203 107006253 chr3 107526849 107526899chr11 59910876 59910926 chr3 112537135 112537185 chr3 113830487113830537 chr3 144182411 144182461 chr3 147055456 147055506 chr3151893743 151893793 chr3 163705686 163705736 chr3 180093425 180093475chr3 186303767 186303817 chr3 189977269 189977319 chr3 192698140192698190 chr4 5341069 5341119 chr4 18950631 18950681 chr4 4207572942075779 chr4 42203712 42203762 chr4 42209456 42209506 chr4 4746856347468613 chr4 59278271 59278321 chr4 63391671 63391721 chr4 6339561563395665 chr4 74257863 74257913 chr4 83859199 83859249 chr4 8733631887336368 chr4 96072171 96072221 chr4 97151285 97151335 chr4 9986924899869298 chr4 100489317 100489367 chr4 111061728 111061778 chr4111663860 111663910 chr4 115424467 115424517 chr4 127743716 127743766chr4 133470625 133470675 chr4 136752614 136752664 chr4 139112101139112151 chr4 155691275 155691325 chr4 163603219 163603269 chr4173246525 173246575 chr4 179025323 179025373 chr4 189382622 189382672chr5 12713567 12713617 chr5 14901464 14901514 chr5 18778859 18778909chr5 18845879 18845929 chr5 21660607 21660657 chr5 23456994 23457044chr5 26706083 26706133 chr5 27861787 27861837 chr5 35553812 35553862chr5 36378746 36378796 chr5 55499292 55499342 chr5 58227113 58227163chr5 59977841 59977891 chr5 60107317 60107367 chr11 70330819 70330869chr5 64342598 64342648 chr5 84545287 84545337 chr11 71591751 71591801chr5 111855398 111855448 chr5 115230822 115230872 chr5 119163301119163351 chr5 143453581 143453631 chr5 143706012 143706062 chr5157375317 157375367 chr5 172313520 172313570 chr6 11757234 11757284 chr614176842 14176892 chr11 80137036 80137086 chr6 24790853 24790903 chr629634362 29634412 chr6 38440742 38440792 chr6 52833260 52833310 chr657741091 57741141 chr6 65369549 65369599 chr6 65710923 65710973 chr667907146 67907196 chr6 82043229 82043279 chr6 82056775 82056825 chr685417365 85417415 chr6 89126628 89126678 chr6 103415113 103415163 chr6106729336 106729386 chr6 110246491 110246541 chr6 111497975 111498025chr6 119054664 119054714 chr6 119343390 119343440 chr6 135549736135549786 chr6 143389193 143389243 chr6 144423057 144423107 chr6158800404 158800454 chr11 103053217 103053267 chr6 167214310 167214360chr11 107198009 107198059 chr11 107389829 107389879 chr11 109736688109736738 chr7 16849885 16849935 chr7 24913330 24913380 chr7 2705780227057852 chr7 39953344 39953394 chr7 42991201 42991251 chr7 4631712746317177 chr11 113372834 113372884 chr7 47824574 47824624 chr7 6836001568360065 chr7 82916121 82916171 chr7 91710219 91710269 chr7 9171877991718829 chr7 91719568 91719618 chr7 95600042 95600092 chr7 9631549896315548 chr7 106173732 106173782 chr7 107538795 107538845 chr7108652794 108652844 chr7 111421108 111421158 chr7 113580624 113580674chr7 121371968 121372018 chr7 133007927 133007977 chr7 148765802148765852 chr7 151777545 151777595 chr8 15184535 15184585 chr8 1814241118142461 chr8 20684749 20684799 chr8 38742904 38742954 chr11 124498634124498684 chr8 51906806 51906856 chr8 62127752 62127802 chr8 9874331898743368 chr8 105437778 105437828 chr8 107808106 107808156 chr8124380690 124380740 chr8 132312046 132312096 chr9 2254585 2254635 chr921717768 21717818 chr9 22867411 22867461 chr9 36255164 36255214 chr974541634 74541684 chr9 77984123 77984173 chr9 77983950 77984000 chr9100578866 100578916 chr12 8805684 8805734 chr12 15139554 15139604 chr1219418547 19418597 chr10 23594763 23594813 chr10 23806290 23806340 chr1232319543 32319593 chr12 45933103 45933153 chr12 49582459 49582509 chr1257532706 57532756 chr12 57538843 57538893 chr12 62999997 63000047 chr1271506337 71506387 chr12 75897636 75897686 chr12 77355926 77355976 chr1283690491 83690541 chr12 101052072 101052122 chr12 122396379 122396429chr12 122943625 122943675 chr10 33884906 33884956 chr12 130852526130852576 chr13 41418998 41419048 chr13 53433275 53433325 chr13 5441842954418479 chr13 58869201 58869251 chr13 59930094 59930144 chr13 6187769761877747 chr13 62898016 62898066 chr13 64120480 64120530 chr13 7643161476431664 chr13 78564562 78564612 chr13 80829823 80829873 chr13 8181172281811772 chr13 81957048 81957098 chr13 87962344 87962394 chr13 9155739491557444 chr13 92653272 92653322 chr13 109859683 109859733 chr1424719699 24719749 chr14 35003289 35003339 chr14 47206019 47206069 chr1451565171 51565221 chr14 51819816 51819866 chr14 64381891 64381941 chr1470228566 70228616 chr14 78860594 78860644 chr14 81682161 81682211 chr1054764210 54764260 chr10 57455931 57455981 chr10 57456545 57456595 chr14104380402 104380452 chr15 23449543 23449593 chr15 27532980 27533030chr10 62138094 62138144 chr10 62143801 62143851 chr15 33053237 33053287chr15 43555536 43555586 chr15 49269282 49269332 chr15 49269612 49269662chr15 49663752 49663802 chr15 50447205 50447255 chr15 51634570 51634620chr10 64768945 64768995 chr15 53320135 53320185 chr10 65149622 65149672chr15 64984973 64985023 chr15 76247442 76247492 chr15 90571221 90571271chr15 92430725 92430775 chr15 92924343 92924393 chr16 57011286 57011336chr16 82604893 82604943 Table 15AO. Repeat Category LTR19A chr1747677535 47677585 chr17 79909235 79909285 chr19 4938834 4938884 chr198773925 8773975 chr19 12201376 12201426 chr19 23147388 23147438 chr12391717 2391767 chr1 8865108 8865158 chr1 11845292 11845342 chr145202748 45202798 chr10 132565859 132565909 chr21 36355142 36355192chr22 22927121 22927171 chrX 139379742 139379792 chrX 140619233140619283 chrY 3274581 3274631 chr2 10364955 10365005 chr2 5392096453921014 chr2 101494934 101494984 chr2 239400787 239400837 chr1162389984 62390034 chr4 33149821 33149871 chr4 33152981 33153031 chr433154101 33154151 chr4 37378924 37378974 chr4 134978789 134978839 chr754835488 54835538 chr8 2077147 2077197 chr8 15402213 15402263 chr9127728957 127729007 chr9 127729901 127729951 chr9 127730909 127730959chr9 127732340 127732390 chr12 33027763 33027813 chr10 42159726 42159776chr13 112532205 112532255 chr14 58555302 58555352 Table 15AP. RepeatCategory LTR1B chr18 31758976 31759026 chr19 48162548 48162598 chr14131184 4131234 chr1 35099514 35099564 chr1 38691569 38691619 chr170542234 70542284 chr1 159135644 159135694 chr1 173665588 173665638 chr1193908027 193908077 chr1 193907942 193907992 chr1 194154572 194154622chr1 213382532 213382582 chr1 226331919 226331969 chr1 229993556229993606 chr10 131670828 131670878 chr1 236247591 236247641 chr2042803404 42803454 chr20 52512114 52512164 chr20 61302668 61302718 chr2115669373 15669423 chr21 28219920 28219970 chr21 29415458 29415508 chr2130422188 30422238 chrX 4094035 4094085 chrX 4931722 4931772 chr114554884 4554934 chrX 18212796 18212846 chrX 25642827 25642877 chrX39695790 39695840 chrX 96318456 96318506 chr2 4687440 4687490 chr221299682 21299732 chr2 61021684 61021734 chr11 25501812 25501862 chr281380224 81380274 chr2 107957674 107957724 chr11 32871659 32871709 chr2140715701 140715751 chr11 34861570 34861620 chr2 163997619 163997669chr2 174374565 174374615 chr2 174376460 174376510 chr2 190016522190016572 chr2 205745752 205745802 chr11 42859152 42859202 chr3 28035082803558 chr11 56545054 56545104 chr3 96280846 96280896 chr3 113173478113173528 chr3 113173689 113173739 chr3 118170736 118170786 chr3150326478 150326528 chr3 176452367 176452417 chr4 45739600 45739650 chr447647420 47647470 chr4 59086046 59086096 chr4 71166923 71166973 chr4126307615 126307665 chr4 126902812 126902862 chr4 134759921 134759971chr4 188667400 188667450 chr4 189801568 189801618 chr4 189813895189813945 chr4 189813948 189813998 chr4 190023732 190023782 chr515438485 15438535 chr5 15523341 15523391 chr5 42871507 42871557 chr542871448 42871498 chr5 51210887 51210937 chr11 70749905 70749955 chr5125547096 125547146 chr5 127378416 127378466 chr5 132367138 132367188chr5 165946248 165946298 chr6 47391933 47391983 chr6 77337398 77337448chr6 77515790 77515840 chr6 87886864 87886914 chr6 121255077 121255127chr6 129044830 129044880 chr11 101437929 101437979 chr6 159446387159446437 chr7 4679403 4679453 chr7 21748943 21748993 chr7 3409161334091663 chr11 112729119 112729169 chr7 96567310 96567360 chr7 124012683124012733 chr7 144976415 144976465 chr8 80322557 80322607 chr9 22781272278177 chr9 15278037 15278087 chr9 30722552 30722602 chr12 2304259123042641 chr12 70826946 70826996 chr12 94957684 94957734 chr10 3698549436985544 chr13 59898916 59898966 chr13 62835634 62835684 chr13 6463263364632683 chr13 75524840 75524890 chr13 87068336 87068386 chr14 3918457839184628 chr14 40975691 40975741 chr14 63830219 63830269 chr14 9413253594132585 chr14 94132354 94132404 chr15 95180603 95180653 chr17 3754746237547512 Table 15AQ. Repeat Category LTR2 chr17 39028619 39028669 chr1739478863 39478913 chr17 39946227 39946277 chr17 41685175 41685225 chr1741692469 41692519 chr17 47390019 47390069 chr17 47630768 47630818 chr1083965962 83966012 chr17 48971947 48971997 chr10 84388160 84388210 chr1751703256 51703306 chr17 53483866 53483916 chr10 85533341 85533391 chr1085596390 85596440 chr10 85596099 85596149 chr17 57412405 57412455 chr1761985429 61985479 chr17 65851151 65851201 chr17 67240401 67240451 chr1769614713 69614763 chr10 88398356 88398406 chr17 75355285 75355335 chr1775597374 75597424 chr17 76114760 76114810 chr17 79071119 79071169 chr1779087451 79087501 chr17 79371613 79371663 chr17 79371457 79371507 chr1780932387 80932437 chr17 81618059 81618109 chr10 94076853 94076903 chr1810593595 10593645 chr18 10596801 10596851 chr18 11283367 11283417 chr1811935591 11935641 chr18 12218754 12218804 chr10 94552386 94552436 chr1813666878 13666928 chr18 14771469 14771519 chr18 18870150 18870200 chr1820350600 20350650 chr18 23350636 23350686 chr18 25255495 25255545 chr1826194652 26194702 chr18 27788984 27789034 chr18 31364486 31364536 chr1836714601 36714651 chr18 41989894 41989944 chr18 45275578 45275628 chr1845582197 45582247 chr18 48526349 48526399 chr18 49404836 49404886 chr1851774084 51774134 chr18 53990546 53990596 chr18 57081932 57081982 chr1857434154 57434204 chr18 61023297 61023347 chr18 67288389 67288439 chr1870350021 70350071 chr18 70350428 70350478 chr10 98979740 98979790 chr1098985580 98985630 chr10 98986394 98986444 chr19 1394000 1394050 chr192920479 2920529 chr19 5373418 5373468 chr19 6140402 6140452 chr10101801489 101801539 chr19 6548612 6548662 chr10 5560121 5560171 chr199679912 9679962 chr19 11565111 11565161 chr19 11681755 11681805 chr1911709629 11709679 chr19 11710173 11710223 chr19 11739028 11739078 chr1911739091 11739141 chr19 11770833 11770883 chr19 11771260 11771310 chr1911900230 11900280 chr19 12032938 12032988 chr19 12266223 12266273 chr1912336320 12336370 chr19 12336879 12336929 chr19 12372005 12372055 chr1912372805 12372855 chr19 12412582 12412632 chr19 13628057 13628107 chr1913653674 13653724 chr19 17369327 17369377 chr19 18357211 18357261 chr1919640096 19640146 chr19 19757388 19757438 chr19 21376987 21377037 chr1932928882 32928932 chr19 38822936 38822986 chr19 40158577 40158627 chr1940565690 40565740 chr19 41110320 41110370 chr19 41955259 41955309 chr10105303232 105303282 chr19 46565057 46565107 chr19 46714435 46714485chr19 46715236 46715286 chr19 47892385 47892435 chr19 47892649 47892699chr19 48609622 48609672 chr19 50053270 50053320 chr19 50064066 50064116chr19 50064209 50064259 chr19 50078294 50078344 chr19 50109581 50109631chr19 50585399 50585449 chr19 50585635 50585685 chr19 50585965 50586015chr19 51610271 51610321 chr19 52780334 52780384 chr19 52780993 52781043chr19 53727515 53727565 chr19 55541854 55541904 chr19 57719926 57719976chr19 57763097 57763147 chr19 57854025 57854075 chr19 57930997 57931047chr19 57933409 57933459 chr19 58054452 58054502 chr19 58121449 58121499chr19 58139364 58139414 chr19 58152373 58152423 chr19 58587523 58587573chr19 59483914 59483964 chr19 60096805 60096855 chr19 60154816 60154866chr19 60156862 60156912 chr19 60162663 60162713 chr19 62390683 62390733chr19 62640591 62640641 chr19 63018268 63018318 chr19 63018568 63018618chr1 6330271 6330321 chr1 9781260 9781310 chr10 117952906 117952956 chr111671821 11671871 chr1 12396086 12396136 chr1 15491504 15491554 chr10118884419 118884469 chr1 19950302 19950352 chr1 20330029 20330079 chr121181175 21181225 chr1 28539266 28539316 chr1 28795544 28795594 chr131119950 31120000 chr1 31504573 31504623 chr1 35040144 35040194 chr135042932 35042982 chr1 36230083 36230133 chr1 37449091 37449141 chr10121396854 121396904 chr1 42494554 42494604 chr1 42499910 42499960 chr10122418270 122418320 chr1 46160842 46160892 chr1 46167580 46167630 chr148031919 48031969 chr1 61923197 61923247 chr1 68747431 68747481 chr170352948 70352998 chr1 84938478 84938528 chr1 89115507 89115557 chr191599728 91599778 chr1 91607444 91607494 chr1 94635003 94635053 chr1101499633 101499683 chr1 108864439 108864489 chr1 109294144 109294194chr1 110171815 110171865 chr1 112329707 112329757 chr1 112711044112711094 chr1 117104818 117104868 chr1 143138973 143139023 chr1144204100 144204150 chr1 144204586 144204636 chr1 145495128 145495178chr10 127063354 127063404 chr1 151560957 151561007 chr1 151651081151651131 chr1 152826889 152826939 chr1 153370515 153370565 chr1153488208 153488258 chr10 127836298 127836348 chr1 154460528 154460578chr1 158583796 158583846 chr1 158590629 158590679 chr10 128376080128376130 chr1 164876979 164877029 chr1 165026379 165026429 chr1166209285 166209335 chr1 168460105 168460155 chr1 168582047 168582097chr1 180799392 180799442 chr1 180799206 180799256 chr1 190494975190495025 chr1 190653142 190653192 chr1 199425162 199425212 chr1200686949 200686999 chr1 201162718 201162768 chr1 202285654 202285704chr1 204672681 204672731 chr1 206360577 206360627 chr1 209445107209445157 chr1 217611296 217611346 chr1 217947911 217947961 chr1221770585 221770635 chr1 222624864 222624914 chr1 223012954 223013004chr1 223609677 223609727 chr1 226787766 226787816 chr1 229134333229134383 chr1 229134392 229134442 chr1 235949708 235949758 chr1236387703 236387753 chr1 237134782 237134832 chr1 238312275 238312325chr1 240031834 240031884 chr1 242235032 242235082 chr1 242234817242234867 chr1 243700264 243700314 chr1 243856550 243856600 chr1243864247 243864297 chr1 244480603 244480653 chr1 244959264 244959314chr1 244966320 244966370 chr1 245039049 245039099 chr1 245105374245105424 chr1 245756160 245756210 chr20 8818304 8818354 chr20 1578385715783907 chr20 15961266 15961316 chr20 16594607 16594657 chr20 1678225516782305 chr20 24895512 24895562 chr20 24929333 24929383 chr20 2562909925629149 chr20 33635124 33635174 chr20 34451466 34451516 chr20 3445182834451878 chr20 35916384 35916434 chr20 42617721 42617771 chr20 5881932258819372 chr20 62587734 62587784 chr20 63283441 63283491 chr21 1354968513549735 chr21 16932929 16932979 chr21 20293673 20293723 chr21 2249203122492081 chr21 22856440 22856490 chr21 24036376 24036426 chr21 2824328128243331 chr21 30326358 30326408 chr21 30529734 30529784 chr21 3131755931317609 chr21 32952678 32952728 chr21 33910458 33910508 chr21 3846567338465723 chr21 39427282 39427332 chr11 799708 799758 chr21 4324159943241649 chr21 43273409 43273459 chr21 43422050 43422100 chr21 4343264443432694 chr21 43439482 43439532 chr21 43447498 43447548 chr21 4405478744054837 chr21 45152007 45152057 chr21 46167919 46167969 chr21 4624618946246239 chr21 46870421 46870471 chr22 16995482 16995532 chr22 1786732317867373 chr22 19716208 19716258 chr22 28136508 28136558 chr22 2907443429074484 chr10 9425346 9425396 chr22 34084277 34084327 chr22 3491832534918375 chr22 35615523 35615573 chr22 36231410 36231460 chr22 3938717739387227 chr22 39392658 39392708 chr22 40399586 40399636 chr22 4136655541366605 chr22 42612276 42612326 chr22 43421174 43421224 chr22 4411395744114007 chr11 3007894 3007944 chr11 3338103 3338153 chr11 34588883458938 chr22 49104351 49104401 chr11 3629871 3629921 chr22 4921135449211404 chr11 3629991 3630041 chr11 3630577 3630627 chrX 40679134067963 chrX 4627084 4627134 chrX 5687488 5687538 chrX 9964303 9964353chrX 9969428 9969478 chrX 18244648 18244698 chrX 19135136 19135186 chrX22874287 22874337 chrX 23078841 23078891 chrX 23079764 23079814 chr115676681 5676731 chrX 34878077 34878127 chrX 36849294 36849344 chrX39741848 39741898 chrX 42073388 42073438 chrX 43679421 43679471 chrX52464224 52464274 chrX 52502437 52502487 chrX 55024806 55024856 chrX61503162 61503212 chrX 63282890 63282940 chrX 72004917 72004967 chrX72336913 72336963 chrX 72429315 72429365 chrX 81671718 81671768 chrX89305745 89305795 chrX 90838663 90838713 chrX 91034983 91035033 chrX91456533 91456583 chrX 91517518 91517568 chrX 91898017 91898067 chrX91902038 91902088 chrX 92731936 92731986 chrX 93687606 93687656 chrX96316297 96316347 chrX 101210726 101210776 chrX 101885783 101885833 chrX101892345 101892395 chrX 104123657 104123707 chr11 9905057 9905107 chrX111818994 111819044 chrX 111993667 111993717 chrX 112065813 112065863chrX 113536277 113536327 chrX 113543646 113543696 chrX 117670386117670436 chrX 117780088 117780138 chrX 118401778 118401828 chrX118916368 118916418 chrX 125013315 125013365 chrX 125757667 125757717chrX 140047110 140047160 chrX 140768038 140768088 chrX 144505686144505736 chrX 145018136 145018186 chrX 145020894 145020944 chrX147342261 147342311 chrX 147470265 147470315 chrY 3932711 3932761 chrY5695388 5695438 chrY 12921017 12921067 chrY 13412083 13412133 chrY13821906 13821956 chrY 13821731 13821781 chrY 14403477 14403527 chrY17871676 17871726 chrY 20410730 20410780 chrY 21567580 21567630 chr2588312 588362 chr2 588190 588240 chr2 5002838 5002888 chr2 77473267747376 chr2 9960860 9960910 chr2 13446752 13446802 chr2 1368796613688016 chr2 13695140 13695190 chr2 13695235 13695285 chr2 1495898614959036 chr2 21007473 21007523 chr2 21008189 21008239 chr2 2590958125909631 chr11 18613976 18614026 chr11 18621921 18621971 chr2 3405645834056508 chr2 38871144 38871194 chr2 40601916 40601966 chr2 4124179541241845 chr2 42831146 42831196 chr2 48407905 48407955 chr2 5128834351288393 chr2 52639544 52639594 chr2 55473500 55473550 chr2 5722355057223600 chr2 62126818 62126868 chr2 65089272 65089322 chr2 6510109465101144 chr11 24503029 24503079 chr2 71248028 71248078 chr2 7159028271590332 chr2 75661610 75661660 chr2 77862406 77862456 chr2 8675830786758357 chr2 95701938 95701988 chr2 97069591 97069641 chr2 9827283198272881 chr2 100608776 100608826 chr2 106217414 106217464 chr2106716520 106716570 chr2 106765290 106765340 chr2 108761618 108761668chr2 108769207 108769257 chr2 109356730 109356780 chr2 111532769111532819 chr2 113703067 113703117 chr2 117982939 117982989 chr2117988174 117988224 chr2 122539220 122539270 chr2 123245158 123245208chr2 128022307 128022357 chr2 128365154 128365204 chr2 128534227128534277 chr2 128534793 128534843 chr2 128832618 128832668 chr2129534141 129534191 chr2 132062687 132062737 chr2 132442114 132442164chr2 133526207 133526257 chr2 136112166 136112216 chr2 139505991139506041 chr2 142562144 142562194 chr2 157477584 157477634 chr2159940655 159940705 chr2 167668621 167668671 chr2 167826266 167826316chr2 171272273 171272323 chr2 171973724 171973774 chr2 173604336173604386 chr2 174376460 174376510 chr2 177087324 177087374 chr2182557052 182557102 chr2 187308758 187308808 chr2 188583849 188583899chr2 188633405 188633455 chr11 39638352 39638402 chr2 200943737200943787 chr2 206421512 206421562 chr2 212397308 212397358 chr2215903950 215904000 chr2 224271102 224271152 chr2 228789477 228789527chr2 228872995 228873045 chr2 231741744 231741794 chr2 232168171232168221 chr2 232468472 232468522 chr2 232476101 232476151 chr2235053053 235053103 chr2 235116680 235116730 chr2 238473878 238473928chr3 3218941 3218991 chr3 3663713 3663763 chr3 5239468 5239518 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151637389 151637439 chr3153752600 153752650 chr3 155873727 155873777 chr3 158626196 158626246chr3 160221378 160221428 chr3 162982713 162982763 chr3 163748181163748231 chr3 164092710 164092760 chr3 171116443 171116493 chr3174310222 174310272 chr3 176659137 176659187 chr3 183829667 183829717chr3 187972204 187972254 chr3 187972142 187972192 chr3 196986684196986734 chr3 197110571 197110621 chr4 2011788 2011838 chr4 20215152021565 chr10 13196866 13196916 chr4 3661548 3661598 chr4 36624983662548 chr4 4414658 4414708 chr4 5678869 5678919 chr4 8288791 8288841chr4 8628791 8628841 chr4 8710528 8710578 chr4 13180233 13180283 chr415243603 15243653 chr4 17320151 17320201 chr4 18440654 18440704 chr418945698 18945748 chr4 22351979 22352029 chr4 22357975 22358025 chr424835719 24835769 chr4 25358912 25358962 chr4 28033977 28034027 chr428039035 28039085 chr4 29979336 29979386 chr4 33128852 33128902 chr436805197 36805247 chr4 37498058 37498108 chr4 37550764 37550814 chr1164803238 64803288 chr4 39899227 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173128662 chr4 173194836 173194886 chr4 174032461 174032511chr4 174343047 174343097 chr4 174716255 174716305 chr4 174723263174723313 chr4 177807252 177807302 chr4 178997835 178997885 chr4179019694 179019744 chr4 180429805 180429855 chr4 184472398 184472448chr4 184994715 184994765 chr4 185045332 185045382 chr4 186127705186127755 chr4 186238592 186238642 chr4 188077113 188077163 chr1168427881 68427931 chr4 191335863 191335913 chr5 227094 227144 chr51613359 1613409 chr5 7095436 7095486 chr5 7141189 7141239 chr5 1884587918845929 chr5 26892790 26892840 chr5 27166782 27166832 chr5 2944211329442163 chr5 31645228 31645278 chr5 36158968 36159018 chr11 6996254769962597 chr5 39542540 39542590 chr5 39711015 39711065 chr5 4285932742859377 chr5 43125518 43125568 chr5 52860959 52861009 chr5 5565913555659185 chr5 58474512 58474562 chr5 59941893 59941943 chr5 6448610064486150 chr5 68607874 68607924 chr5 74054181 74054231 chr5 7405714774057197 chr5 78595338 78595388 chr5 79752149 79752199 chr5 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chr11 81394145 81394195 chr626183592 26183642 chr6 26670219 26670269 chr6 27960286 27960336 chr628411705 28411755 chr6 29768715 29768765 chr11 82784357 82784407 chr631678079 31678129 chr6 31924180 31924230 chr6 31925025 31925075 chr1185368382 85368432 chr6 38811313 38811363 chr6 42788729 42788779 chr643657957 43658007 chr6 47649941 47649991 chr6 56986133 56986183 chr663555999 63556049 chr6 65010255 65010305 chr6 66334642 66334692 chr666643839 66643889 chr6 68885928 68885978 chr6 69251312 69251362 chr1190197308 90197358 chr6 75174105 75174155 chr6 75179909 75179959 chr689368118 89368168 chr6 93552569 93552619 chr10 912747 912797 chr6101445672 101445722 chr6 107116179 107116229 chr6 108640785 108640835chr6 111398568 111398618 chr6 111530203 111530253 chr10 914729 914779chr6 116688533 116688583 chr11 95355336 95355386 chr6 121706665121706715 chr6 123057462 123057512 chr6 131287208 131287258 chr6131688049 131688099 chr6 139591211 139591261 chr6 141772157 141772207chr6 147754972 147755022 chr6 153802926 153802976 chr6 161778185161778235 chr6 164343114 164343164 chr6 166878666 166878716 chr6167281024 167281074 chr6 169812278 169812328 chr6 169813003 169813053chr7 581860 581910 chr7 1111718 1111768 chr11 107559488 107559538 chr71914999 1915049 chr11 107813092 107813142 chr7 4805043 4805093 chr76734197 6734247 chr7 7580027 7580077 chr7 12373055 12373105 chr723584344 23584394 chr7 24507279 24507329 chr7 24577109 24577159 chr730590054 30590104 chr7 32544032 32544082 chr7 32544934 32544984 chr732863621 32863671 chr7 36415370 36415420 chr7 39513963 39514013 chr739663241 39663291 chr7 43605111 43605161 chr7 43699001 43699051 chr743701354 43701404 chr7 44628855 44628905 chr7 48263214 48263264 chr751923255 51923305 chr7 54689646 54689696 chr7 55715185 55715235 chr757214790 57214840 chr7 57345133 57345183 chr7 63382628 63382678 chr763386794 63386844 chr7 63467287 63467337 chr7 63661619 63661669 chr764189290 64189340 chr7 65498298 65498348 chr7 66401858 66401908 chr767230852 67230902 chr7 70313913 70313963 chr7 72965786 72965836 chr772984858 72984908 chr7 75120415 75120465 chr7 75262888 75262938 chr791779609 91779659 chr7 97504904 97504954 chr7 100048567 100048617 chr7100679139 100679189 chr7 100679018 100679068 chr7 102353546 102353596chr7 104429609 104429659 chr7 104716150 104716200 chr7 106587234106587284 chr7 114778681 114778731 chr7 125853544 125853594 chr7136369064 136369114 chr7 138225573 138225623 chr11 118610680 118610730chr7 144448326 144448376 chr11 119552407 119552457 chr7 152936797152936847 chr7 153338632 153338682 chr7 154112101 154112151 chr7154111917 154111967 chr7 156308736 156308786 chr8 236845 236895 chr8419731 419781 chr8 2943936 2943986 chr8 5664060 5664110 chr8 69133866913436 chr8 9144681 9144731 chr8 11806400 11806450 chr8 1180819511808245 chr8 11830995 11831045 chr8 12409569 12409619 chr8 1258044012580490 chr8 15418429 15418479 chr8 18479985 18480035 chr8 2411505624115106 chr8 28475553 28475603 chr8 30451685 30451735 chr8 3311257433112624 chr8 33574521 33574571 chr8 41471654 41471704 chr8 4895189848951948 chr8 49043557 49043607 chr8 56663509 56663559 chr8 5673873656738786 chr8 57864910 57864960 chr8 57864660 57864710 chr8 5965384359653893 chr8 67221695 67221745 chr8 71497749 71497799 chr8 7499465174994701 chr8 78583485 78583535 chr8 95246983 95247033 chr8 103402296103402346 chr8 103970520 103970570 chr8 108139249 108139299 chr8112794021 112794071 chr8 116041190 116041240 chr8 122774184 122774234chr8 124455023 124455073 chr8 134577670 134577720 chr8 139954482139954532 chr8 141200394 141200444 chr8 144223084 144223134 chr8144525565 144525615 chr8 144734822 144734872 chr8 144815880 144815930chr8 144868006 144868056 chr8 144870176 144870226 chr8 146299504146299554 chr9 4398875 4398925 chr9 5221232 5221282 chr9 5707479 5707529chr9 6995119 6995169 chr9 7223834 7223884 chr9 15129441 15129491 chr919188085 19188135 chr9 32297420 32297470 chr9 34630320 34630370 chr937108937 37108987 chr9 37452896 37452946 chr9 64750083 64750133 chr973779268 73779318 chr9 74434560 74434610 chr9 82414103 82414153 chr984588809 84588859 chr9 85537862 85537912 chr9 86164713 86164763 chr986165447 86165497 chr9 86278149 86278199 chr9 86492458 86492508 chr989431631 89431681 chr9 92764974 92765024 chr9 96256903 96256953 chr998510946 98510996 chr9 101445869 101445919 chr9 101904997 101905047 chr9102777072 102777122 chr9 103696290 103696340 chr12 557741 557791 chr12668516 668566 chr9 125842875 125842925 chr9 126187445 126187495 chr9131559432 131559482 chr9 131560295 131560345 chr9 131623764 131623814chr9 131624234 131624284 chr9 132107939 132107989 chr9 133768441133768491 chr9 133775083 133775133 chr9 134011420 134011470 chr9135379180 135379230 chr9 135845549 135845599 chr12 3433959 3434009 chr1022165642 22165692 chr12 7586337 7586387 chr12 8117084 8117134 chr128326207 8326257 chr12 12151599 12151649 chr12 17328085 17328135 chr1231794390 31794440 chr12 31918372 31918422 chr12 32456617 32456667 chr1239269476 39269526 chr12 41122714 41122764 chr12 48420535 48420585 chr1250945002 50945052 chr12 55406124 55406174 chr12 59258225 59258275 chr1263674690 63674740 chr12 67850931 67850981 chr12 71498252 71498302 chr1272944885 72944935 chr12 72952953 72953003 chr12 86149346 86149396 chr1287080333 87080383 chr12 91836829 91836879 chr10 29653393 29653443 chr1293713349 93713399 chr12 94284872 94284922 chr12 94457521 94457571 chr1299061198 99061248 chr12 99529322 99529372 chr12 106075761 106075811chr10 30769582 30769632 chr12 112006296 112006346 chr12 118805078118805128 chr12 123664698 123664748 chr12 124945329 124945379 chr1034116294 34116344 chr12 126842488 126842538 chr10 35262240 35262290chr12 131255695 131255745 chr12 131776885 131776935 chr13 1755535817555408 chr13 18906462 18906512 chr13 19129242 19129292 chr13 2125539221255442 chr13 23299820 23299870 chr13 23309965 23310015 chr13 2376093423760984 chr13 26497864 26497914 chr10 37049645 37049695 chr13 2994974729949797 chr13 29973437 29973487 chr13 33069039 33069089 chr13 3751039937510449 chr13 39673030 39673080 chr13 39828061 39828111 chr13 4137893441378984 chr13 47613614 47613664 chr13 50531518 50531568 chr13 5397833553978385 chr13 54234495 54234545 chr13 54350050 54350100 chr13 6076665160766701 chr13 66141950 66142000 chr13 68174999 68175049 chr13 6939847369398523 chr13 79762676 79762726 chr13 82088346 82088396 chr13 8278730982787359 chr13 84402822 84402872 chr13 86994951 86995001 chr10 4308553843085588 chr10 43148067 43148117 chr10 43149330 43149380 chr10 4314899743149047 chr10 43149450 43149500 chr13 93720916 93720966 chr13 100790321100790371 chr13 101054652 101054702 chr13 101054501 101054551 chr13106261452 106261502 chr13 111894512 111894562 chr13 111896321 111896371chr13 112916909 112916959 chr14 29699751 29699801 chr14 3242256432422614 chr14 38222090 38222140 chr14 42384193 42384243 chr14 4639430546394355 chr14 47264521 47264571 chr14 48076600 48076650 chr14 4807692548076975 chr14 54430030 54430080 chr14 62106310 62106360 chr14 6391447963914529 chr14 64413606 64413656 chr14 72007549 72007599 chr14 7204032672040376 chr14 78921071 78921121 chr14 81799144 81799194 chr14 8205137582051425 chr10 54112943 54112993 chr14 88414597 88414647 chr10 5474170654741756 chr14 91205145 91205195 chr14 100704576 100704626 chr1059198618 59198668 chr14 101710619 101710669 chr14 103476977 103477027chr15 21421670 21421720 chr15 23774934 23774984 chr15 32130203 32130253chr15 32270808 32270858 chr15 34336963 34337013 chr15 51839385 51839435chr15 52895510 52895560 chr15 53518942 53518992 chr15 58570041 58570091chr10 65836185 65836235 chr15 59452602 59452652 chr15 60303393 60303443chr10 66899702 66899752 chr15 67367632 67367682 chr10 68867417 68867467chr15 72889555 72889605 chr10 69267666 69267716 chr15 84074086 84074136chr15 87252886 87252936 chr15 87790755 87790805 chr15 92194416 92194466chr10 70416347 70416397 chr10 70451684 70451734 chr16 10035785 10035835chr16 10358587 10358637 chr16 12033503 12033553 chr10 71420401 71420451chr10 71420010 71420060 chr16 14723269 14723319 chr16 17575064 17575114chr10 71729257 71729307 chr16 28191231 28191281 chr16 28997042 28997092chr16 29738949 29738999 chr16 29757131 29757181 chr16 30588126 30588176chr16 30593884 30593934 chr16 30606589 30606639 chr16 31103357 31103407chr16 31332504 31332554 chr16 35930163 35930213 chr16 46679745 46679795chr16 47185122 47185172 chr10 73044293 73044343 chr16 52842471 52842521chr10 73067037 73067087 chr16 56349692 56349742 chr16 56674389 56674439chr16 61053487 61053537 chr16 62218111 62218161 chr16 62457890 62457940chr16 65674146 65674196 chr10 73648695 73648745 chr10 73864084 73864134chr10 74008605 74008655 chr16 70225335 70225385 chr10 74145595 74145645chr16 73913231 73913281 chr16 77873660 77873710 chr16 83149237 83149287chr16 84155681 84155731 chr16 87195010 87195060 chr17 2657301 2657351chr17 2895707 2895757 chr17 6822033 6822083 chr10 77999698 77999748chr17 8172404 8172454 chr17 8354869 8354919 chr17 8355875 8355925 chr1714006847 14006897 chr17 14078969 14079019 chr17 19497434 19497484 chr1719611606 19611656 chr17 21130643 21130693 chr17 21175835 21175885 chr1725792985 25793035 chr17 26702909 26702959 chr17 26711366 26711416 chr1727309410 27309460 chr17 28713650 28713700 chr17 31143847 31143897 chr1732241037 32241087 chr17 32403847 32403897 chr17 33527835 33527885 chr1733876060 33876110 chr17 37586734 37586784 chr17 37678539 37678589 Table15AR. Repeat Category LTR22 chr17 39478863 39478913 chr17 6724040167240451 chr17 75355285 75355335 chr17 80932387 80932437 chr18 1477146914771519 chr18 25255495 25255545 chr19 5373418 5373468 chr19 3292888232928932 chr19 47892385 47892435 chr19 47892649 47892699 chr19 5785402557854075 chr19 60096805 60096855 chr19 62390683 62390733 chr1 1239608612396136 chr1 20330029 20330079 chr1 94635003 94635053 chr1 153370515153370565 chr1 168460105 168460155 chr1 190494975 190495025 chr1190653142 190653192 chr1 200686949 200686999 chr1 223012954 223013004chr21 13549685 13549735 chr21 28243281 28243331 chr10 9425346 9425396chrX 36849294 36849344 chrX 63282890 63282940 chrX 101210726 101210776chrX 118916368 118916418 chrX 140768038 140768088 chrX 145018136145018186 chrX 145020894 145020944 chrX 147470265 147470315 chr271590282 71590332 chr2 86758307 86758357 chr2 109356730 109356780 chr2167668621 167668671 chr2 232168171 232168221 chr3 111684064 111684114chr3 127106844 127106894 chr3 149564090 149564140 chr3 171116443171116493 chr4 70963685 70963735 chr4 174343047 174343097 chr5 2689279026892840 chr5 27166782 27166832 chr5 169858482 169858532 chr5 178319823178319873 chr11 80470448 80470498 chr11 85368382 85368432 chr6 5698613356986183 chr6 63555999 63556049 chr6 65010255 65010305 chr6 6925131269251362 chr6 101445672 101445722 chr6 107116179 107116229 chr1195355336 95355386 chr6 123057462 123057512 chr11 107813092 107813142chr7 39663241 39663291 chr7 70313913 70313963 chr7 106587234 106587284chr7 125853544 125853594 chr7 152936797 152936847 chr8 5664060 5664110chr8 33112574 33112624 chr8 134577670 134577720 chr9 5221232 5221282chr9 6995119 6995169 chr9 98510946 98510996 chr12 17328085 17328135chr12 39269476 39269526 chr12 41122714 41122764 chr12 59258225 59258275chr12 87080333 87080383 chr12 99061198 99061248 chr12 124945329124945379 chr13 18906462 18906512 chr13 23299820 23299870 chr13 2330996523310015 chr13 69398473 69398523 chr10 43085538 43085588 chr14 4726452147264571 chr14 78921071 78921121 chr15 21421670 21421720 chr15 5289551052895560 chr15 87252886 87252936 chr16 87195010 87195060 Table 15AS.Repeat Category LTR28 chr18 20350600 20350650 chr18 26194652 26194702chr18 49404836 49404886 chr18 61023297 61023347 chr1 61923197 61923247chr1 117104818 117104868 chr20 33635124 33635174 chr21 22856440 22856490chr21 46870421 46870471 chr2 136112166 136112216 chr11 39638352 39638402chr3 110264129 110264179 chr4 45138564 45138614 chr4 135926320 135926370chr4 178997835 178997885 chr5 7141189 7141239 chr5 39711015 39711065chr6 21574229 21574279 chr6 141772157 141772207 chr6 169813003 169813053chr7 72965786 72965836 chr7 104429609 104429659 chr8 49043557 49043607chr8 95246983 95247033 chr9 84588809 84588859 chr12 12151599 12151649chr14 88414597 88414647 chr15 32270808 32270858 chr17 31143847 31143897chr17 32241037 32241087 Table 15AT. Repeat Category LTR29 chr17 4763076847630818 chr18 70350021 70350071 chr18 70350428 70350478 chr1 3744909137449141 chr1 48031919 48031969 chr20 35916384 35916434 chr22 4136655541366605 chrX 4067913 4067963 chrX 5687488 5687538 chrX 4207338842073438 chrX 52502437 52502487 chrX 90838663 90838713 chrX 9631629796316347 chrX 111993667 111993717 chr2 117982939 117982989 chr2117988174 117988224 chr2 157477584 157477634 chr2 187308758 187308808chr2 228789477 228789527 chr3 15405995 15406045 chr11 47633579 47633629chr3 54166345 54166395 chr3 115143053 115143103 chr3 183829667 183829717chr10 13196866 13196916 chr4 25358912 25358962 chr4 29979336 29979386chr11 68427881 68427931 chr11 69962547 69962597 chr5 55659135 55659185chr5 78595338 78595388 chr5 167886974 167887024 chr6 26074279 26074329chr6 27960286 27960336 chr6 42788729 42788779 chr6 131688049 131688099chr7 48263214 48263264 chr7 100679139 100679189 chr7 100679018 100679068chr8 56663509 56663559 chr8 144223084 144223134 chr9 92764974 92765024chr9 132107939 132107989 chr12 31794390 31794440 chr12 32456617 32456667chr13 26497864 26497914 chr13 41378934 41378984 chr13 79762676 79762726chr14 29699751 29699801 chr10 54112943 54112993 chr10 70416347 70416397chr10 70451684 70451734 chr16 12033503 12033553 chr10 74145595 74145645Table 15AU. Repeat Category LTR30 chr18 39927387 39927437 chr18 4617695446177004 chr19 467128 467178 chr1 146964366 146964416 chr11 299259299309 chrX 79817252 79817302 chrX 79822965 79823015 chrX 8570803185708081 chrX 153302858 153302908 chr3 6084037 6084087 chr3 9974839999748449 chr3 104594079 104594129 chr3 147057055 147057105 chr3155406717 155406767 chr3 192143533 192143583 chr4 43335826 43335876 chr463843319 63843369 chr4 70558024 70558074 chr4 130841681 130841731 chr4136002782 136002832 chr4 156920679 156920729 chr4 156921015 156921065chr4 179406691 179406741 chr5 28332941 28332991 chr5 105284982 105285032chr11 82653958 82654008 chr11 82657767 82657817 chr6 32636170 32636220chr6 38812510 38812560 chr6 68745751 68745801 chr6 118984435 118984485chr12 14759905 14759955 chr10 28792964 28793014 chr13 45483153 45483203chr13 58639895 58639945 chr13 91381860 91381910 chr14 41705838 41705888chr14 41992258 41992308 chr14 41993984 41994034 chr14 41994336 41994386chr14 41994528 41994578 chr14 81842247 81842297 chr10 54243508 54243558Table 15AV. Repeat Category LTR33A chr17 39094931 39094981 chr1741664501 41664551 chr17 72818570 72818620 chr17 75886905 75886955 chr1092585098 92585148 chr18 47323488 47323538 chr19 3517224 3517274 chr10101552627 101552677 chr19 11286591 11286641 chr19 12944228 12944278chr19 46447598 46447648 chr19 49669421 49669471 chr19 51685203 51685253chr19 52610298 52610348 chr19 59572389 59572439 chr19 60008278 60008328chr1 23822547 23822597 chr1 24549677 24549727 chr1 30805080 30805130chr1 32889254 32889304 chr1 36631178 36631228 chr1 56885089 56885139chr1 58990315 58990365 chr1 198839665 198839715 chr1 242244752 242244802chr20 46162025 46162075 chr20 49474599 49474649 chr20 50250050 50250100chr21 26125060 26125110 chr22 16158992 16159042 chr22 43338093 43338143chr22 46556098 46556148 chr11 3403708 3403758 chr11 3403613 3403663 chrX16506687 16506737 chrX 21552576 21552626 chrX 21552335 21552385 chrX24638372 24638422 chr11 6351533 6351583 chrX 45673269 45673319 chrX75225019 75225069 chrX 117419902 117419952 chrX 121602113 121602163chr11 12573813 12573863 chrY 7812612 7812662 chr2 471654 471704 chr24883365 4883415 chr2 42143114 42143164 chr2 55705088 55705138 chr273368258 73368308 chr2 86019989 86020039 chr2 114558648 114558698 chr1132545341 32545391 chr2 131707434 131707484 chr2 139303651 139303701 chr2139303577 139303627 chr2 174023621 174023671 chr2 181907969 181908019chr2 182319616 182319666 chr2 185233466 185233516 chr2 189235924189235974 chr11 42807628 42807678 chr2 217674089 217674139 chr2220104294 220104344 chr2 222983630 222983680 chr3 17765611 17765661 chr339504671 39504721 chr3 44174416 44174466 chr3 88711279 88711329 chr1159139751 59139801 chr3 108807770 108807820 chr3 117234435 117234485 chr3131146964 131147014 chr3 141950363 141950413 chr3 160592849 160592899chr3 195306735 195306785 chr3 197514149 197514199 chr4 6083370 6083420chr4 6083158 6083208 chr4 6084408 6084458 chr4 7575155 7575205 chr1164141813 64141863 chr4 10617774 10617824 chr4 73345511 73345561 chr479084746 79084796 chr4 102542122 102542172 chr4 129892698 129892748 chr4137017604 137017654 chr4 142706444 142706494 chr4 185961090 185961140chr4 189443993 189444043 chr4 190056762 190056812 chr4 191170863191170913 chr5 6876057 6876107 chr5 6875834 6875884 chr11 6972035969720409 chr5 30924089 30924139 chr5 40303154 40303204 chr5 5782344457823494 chr5 57823224 57823274 chr5 61379468 61379518 chr5 6501371965013769 chr10 14199990 14200040 chr5 123297030 123297080 chr5 145264606145264656 chr5 148350176 148350226 chr11 78349472 78349522 chr1183181720 83181770 chr11 83181457 83181507 chr6 34768366 34768416 chr638811313 38811363 chr6 39591164 39591214 chr6 69408524 69408574 chr695628047 95628097 chr6 127725475 127725525 chr6 133250655 133250705chr11 98499635 98499685 chr6 160167226 160167276 chr11 105704033105704083 chr7 976211 976261 chr7 90775449 90775499 chr7 112986720112986770 chr7 150019757 150019807 chr7 150845493 150845543 chr8 47416974741747 chr8 26607969 26608019 chr8 87759115 87759165 chr8 127366210127366260 chr8 141488360 141488410 chr9 2245219 2245269 chr9 6709538967095439 chr9 69633208 69633258 chr9 95021737 95021787 chr9 123538221123538271 chr9 127190731 127190781 chr12 25496369 25496419 chr1240264484 40264534 chr12 45948540 45948590 chr12 48757183 48757233 chr1250843388 50843438 chr10 27948562 27948612 chr12 120213417 120213467chr12 120527391 120527441 chr12 124272184 124272234 chr12 125579367125579417 chr12 125579180 125579230 chr12 127991053 127991103 chr12127990901 127990951 chr12 130131599 130131649 chr12 130208868 130208918chr12 130294882 130294932 chr13 52748659 52748709 chr13 8119522681195276 chr13 107383651 107383701 chr13 111156377 111156427 chr13111156307 111156357 chr14 21210758 21210808 chr14 32420193 32420243chr14 45065795 45065845 chr14 69771401 69771451 chr14 90711747 90711797chr14 94030877 94030927 chr14 98100114 98100164 chr15 29265912 29265962chr15 57539031 57539081 chr15 60331970 60332020 chr15 70711252 70711302chr15 92306831 92306881 chr15 98571503 98571553 chr16 5143793 5143843chr16 26242030 26242080 chr16 52458502 52458552 chr16 59177054 59177104chr17 12456603 12456653 Table 15AW. Repeat Category LTR36 chr19 1424049014240540 chr19 46937792 46937842 chr1 48697941 48697991 chr1 6187550661875556 chr1 107719601 107719651 chr1 245078798 245078848 chr2126174140 26174190 chr21 42244634 42244684 chr21 44193736 44193786 chr2243038571 43038621 chrX 3270375 3270425 chrX 50138582 50138632 chrX52018605 52018655 chr2 47176491 47176541 chr2 140715701 140715751 chr2170909583 170909633 chr2 232481702 232481752 chr3 30101478 30101528 chr337380559 37380609 chr3 52710061 52710111 chr3 190890346 190890396 chr44534587 4534637 chr4 41083368 41083418 chr4 169550949 169550999 chr4190074769 190074819 chr4 190075321 190075371 chr4 190236932 190236982chr5 51210887 51210937 chr5 177717796 177717846 chr6 11030566 11030616chr6 161105726 161105776 chr7 21794497 21794547 chr11 111650778111650828 chr11 113671995 113672045 chr7 96683857 96683907 chr1018383321 18383371 chr9 67117678 67117728 chr9 92241682 92241732 chr9107263773 107263823 chr12 698565 698615 chr12 4815043 4815093 chr1244254350 44254400 chr12 44782648 44782698 chr12 67850931 67850981 chr1328427818 28427868 chr14 53658221 53658271 chr15 21322944 21322994 chr1521324469 21324519 chr15 43478158 43478208 chr16 80956986 80957036 Table15AX. Repeat Category LTR45B chr17 71536945 71536995 chr17 7153688471536934 chr10 97543300 97543350 chr19 8131777 8131827 chr19 3362650433626554 chr19 49770911 49770961 chr1 225019719 225019769 chr1 226282767226282817 chr20 56718264 56718314 chr21 23025494 23025544 chr22 2258746722587517 chr11 5576540 5576590 chr2 9872410 9872460 chr3 5991047 5991097chr3 105727307 105727357 chr3 123624609 123624659 chr11 6719287867192928 chr11 67193429 67193479 chr5 1824488 1824538 chr7 38242923824342 chr7 6494428 6494478 chr7 23150968 23151018 chr7 4807627248076322 chr7 65852113 65852163 chr7 99536327 99536377 chr8 9742788397427933 chr12 27558921 27558971 chr12 64327527 64327577 chr12 9253783692537886 chr10 30054828 30054878 chr13 69398473 69398523 chr14 2533992925339979 chr14 75174051 75174101 chr10 70158564 70158614 Table 15AY.Repeat Category LTR45C chr17 37840905 37840955 chr10 102632566 102632616chr19 60979460 60979510 chr1 3451431 3451481 chr20 31184057 31184107chr20 47582146 47582196 chr21 25300956 25301006 chr22 43765928 43765978chr2 104535742 104535792 chr3 130332571 130332621 chr3 190371417190371467 chr4 141203863 141203913 chr5 912356 912406 chr5 3183944431839494 chr5 93423230 93423280 chr5 140676464 140676514 chr6 1458812014588170 chr6 168341544 168341594 chr7 4360548 4360598 chr7 7149642771496477 chr7 72952260 72952310 chr7 151044429 151044479 chr9 2769731027697360 chr9 33161868 33161918 chr12 97976341 97976391 chr12 116694534116694584 chr12 131850894 131850944 chr13 44068136 44068186 chr1344074326 44074376 chr13 62785215 62785265 chr13 63526352 63526402 chr1525391384 25391434 chr16 16885017 16885067 chr17 4767595 4767645 Table15AZ. Repeat Category LTR46 chr17 42482324 42482374 chr17 7908745179087501 chr18 9687455 9687505 chr19 14725069 14725119 chr19 3774337537743425 chr19 40052996 40053046 chr19 54663365 54663415 chr19 6256541162565461 chr1 1014584 1014634 chr1 39580304 39580354 chr1 157338607157338657 chr22 43833974 43834024 chrX 73291486 73291536 chrX 138790465138790515 chrX 139479401 139479451 chrX 141495800 141495850 chrY 33574643357514 chr2 89449668 89449718 chr2 89731498 89731548 chr2 9947620999476259 chr2 201932701 201932751 chr2 201933265 201933315 chr4 3336657733366627 chr11 68535566 68535616 chr11 95921253 95921303 chr11 9592870695928756 chr11 110566207 110566257 chr11 115903812 115903862 chr777958420 77958470 chr7 97993177 97993227 chr8 143865047 143865097 chr95490959 5491009 chrX 139366249 139366299 chrX 139366339 139366389 chr1283807340 83807390 chr12 131976388 131976438 chr14 102380087 102380137chr16 75495898 75495948 chr17 33866426 33866476 Table 15BA. RepeatCategory LTR47A chr10 88437821 88437871 chr18 9748034 9748084 chr1835417984 35418034 chr18 59263778 59263828 chr18 74012476 74012526 chr1942188319 42188369 chr19 44459047 44459097 chr19 54929211 54929261 chr1141717898 141717948 chr1 198193523 198193573 chr1 227269693 227269743chr1 230159655 230159705 chr10 134251419 134251469 chr22 3776587137765921 chr22 41298475 41298525 chr22 41371678 41371728 chrX 4699619746996247 chrX 109550892 109550942 chrX 134676196 134676246 chr2 797109797159 chr2 60925446 60925496 chr11 38491161 38491211 chr2 207240404207240454 chr2 223890228 223890278 chr2 225818525 225818575 chr2230461139 230461189 chr3 45208409 45208459 chr3 51861954 51862004 chr3108172717 108172767 chr11 66511904 66511954 chr4 187916651 187916701chr5 115169987 115170037 chr5 125209670 125209720 chr5 131461571131461621 chr5 139632166 139632216 chr11 76173418 76173468 chr6 2625366726253717 chr6 31075637 31075687 chr6 163388692 163388742 chr7 7076129870761348 chr7 74987338 74987388 chr7 156640825 156640875 chr7 157162002157162052 chr8 20768318 20768368 chr8 144295522 144295572 chr8 144862249144862299 chr9 103838681 103838731 chr12 19661140 19661190 chr12129642208 129642258 chr13 25892907 25892957 chr13 61001781 61001831chr13 108918272 108918322 chr14 63572535 63572585 chr15 3269606432696114 chr16 14285640 14285690 chr16 68066143 68066193 chr17 326904326954 chr17 4759712 4759762 chr17 14626539 14626589 Table 15BC. RepeatCategory LTR48 chr10 85992953 85993003 chr17 65990673 65990723 chr1766301781 66301831 chr17 66303100 66303150 chr17 78936307 78936357 chr1820250868 20250918 chr18 27658717 27658767 chr18 59067516 59067566 chr1913714376 13714426 chr19 45491551 45491601 chr19 45493111 45493161 chr1945495804 45495854 chr19 45497455 45497505 chr19 45501660 45501710 chr10113903581 113903631 chr1 3358006 3358056 chr1 7845181 7845231 chr19407954 9408004 chr1 34754419 34754469 chr1 104788206 104788256 chr1112707296 112707346 chr1 184499204 184499254 chr1 198815657 198815707chr1 206360577 206360627 chr1 206452325 206452375 chr1 206452217206452267 chr1 217268950 217269000 chr1 225638433 225638483 chr1244930893 244930943 chr20 31064004 31064054 chr21 17927081 17927131 chrX8072165 8072215 chrX 27702543 27702593 chrX 41365260 41365310 chrX52732420 52732470 chrX 107578791 107578841 chrX 109434157 109434207 chrX111816968 111817018 chrX 112045793 112045843 chr2 2876140 2876190 chr211318389 11318439 chr11 20152409 20152459 chr2 44263336 44263386 chr248875420 48875470 chr2 58315050 58315100 chr2 65022818 65022868 chr278066424 78066474 chr11 30840018 30840068 chr2 113435500 113435550 chr2125260480 125260530 chr2 164855114 164855164 chr2 189343679 189343729chr2 231470809 231470859 chr3 16667365 16667415 chr3 18862739 18862789chr3 77443094 77443144 chr3 137795862 137795912 chr3 164445099 164445149chr4 57533616 57533666 chr4 84865911 84865961 chr4 91007165 91007215chr4 97922037 97922087 chr4 121114209 121114259 chr4 130058115 130058165chr4 152236221 152236271 chr4 160186307 160186357 chr5 5135821 5135871chr5 68232572 68232622 chr5 76302357 76302407 chr5 105213189 105213239chr5 130134327 130134377 chr5 137773859 137773909 chr5 141301187141301237 chr5 177667040 177667090 chr5 178389283 178389333 chr614494024 14494074 chr6 15071326 15071376 chr6 26142481 26142531 chr627702588 27702638 chr6 27929112 27929162 chr6 53116649 53116699 chr6107367209 107367259 chr6 136228076 136228126 chr6 142138041 142138091chr6 158787186 158787236 chr7 84577091 84577141 chr11 116672036116672086 chr7 99037161 99037211 chr7 110845006 110845056 chr7 154112101154112151 chr7 154111917 154111967 chr8 6546819 6546869 chr8 89728118972861 chr8 29257775 29257825 chr8 39782594 39782644 chr8 6212999362130043 chr8 116360637 116360687 chr8 120939691 120939741 chr9 1109032511090375 chr9 32805406 32805456 chr9 41213594 41213644 chr9 7139039571390445 chr9 80454672 80454722 chr9 86605059 86605109 chr9 9276705992767109 chr9 127702445 127702495 chr12 5570223 5570273 chr12 127937241127937291 chr13 24903239 24903289 chr13 32121780 32121830 chr13 4379980243799852 chr10 41984579 41984629 chr13 72292849 72292899 chr13 7229266872292718 chr14 66064461 66064511 chr14 79420434 79420484 chr15 3237817132378221 chr15 57422872 57422922 chr15 61909551 61909601 chr15 8910723989107289 chr15 89773235 89773285 chr16 10337191 10337241 chr16 1035858710358637 chr16 14373254 14373304 chr16 18950563 18950613 chr16 6001986960019919 chr10 73434940 73434990 Table 15BD. Repeat Category LTR48Bchr17 65990673 65990723 chr18 20250868 20250918 chr18 27658717 27658767chr1 34754419 34754469 chr1 112707296 112707346 chr1 198815657 198815707chr1 206360577 206360627 chr1 225638433 225638483 chr1 244930893244930943 chrX 8072165 8072215 chrX 27702543 27702593 chrX 4136526041365310 chrX 52732420 52732470 chrX 112045793 112045843 chr2 28761402876190 chr2 48875420 48875470 chr2 65022818 65022868 chr2 125260480125260530 chr2 164855114 164855164 chr2 189343679 189343729 chr318862739 18862789 chr3 77443094 77443144 chr3 164445099 164445149 chr457533616 57533666 chr4 84865911 84865961 chr4 121114209 121114259 chr4152236221 152236271 chr4 160186307 160186357 chr5 5135821 5135871 chr568232572 68232622 chr5 141301187 141301237 chr6 14494024 14494074 chr615071326 15071376 chr6 27929112 27929162 chr6 53116649 53116699 chr6136228076 136228126 chr6 142138041 142138091 chr8 8972811 8972861 chr829257775 29257825 chr8 39782594 39782644 chr8 116360637 116360687 chr8120939691 120939741 chr9 86605059 86605109 chr9 127702445 127702495chr12 5570223 5570273 chr12 127937241 127937291 chr13 24903239 24903289chr13 32121780 32121830 chr13 43799802 43799852 chr14 79420434 79420484chr15 57422872 57422922 chr15 89107239 89107289 chr16 10337191 10337241chr16 10358587 10358637 chr16 14373254 14373304 chr16 60019869 60019919Table 15BE. Repeat Category LTR5 chr17 38212629 38212679 chr17 3895088738950937 chr17 41916256 41916306 chr17 42159421 42159471 chr17 4359612843596178 chr17 47210829 47210879 chr17 47213443 47213493 chr17 4721515247215202 chr17 53176089 53176139 chr17 57841643 57841693 chr17 5808748958087539 chr17 58119386 58119436 chr10 86582408 86582458 chr17 7322907273229122 chr17 74174621 74174671 chr17 74455813 74455863 chr17 7465728974657339 chr17 74657221 74657271 chr17 77260496 77260546 chr17 7726146977261519 chr10 91128615 91128665 chr18 7262926 7262976 chr18 1193559111935641 chr18 22759338 22759388 chr18 26785077 26785127 chr18 2764341427643464 chr18 29034028 29034078 chr18 30087080 30087130 chr18 3303240433032454 chr18 33036041 33036091 chr18 37016758 37016808 chr18 4191999541920045 chr18 43598178 43598228 chr18 51448579 51448629 chr18 6289295862893008 chr18 63999808 63999858 chr18 75923806 75923856 chr10 100731341100731391 chr19 3956579 3956629 chr10 101245038 101245088 chr19 83581738358223 chr19 9179990 9180040 chr19 9558728 9558778 chr19 95974609597510 chr19 9760951 9761001 chr19 11583758 11583808 chr19 1209989612099946 chr19 12173944 12173994 chr19 12229801 12229851 chr19 1223226112232311 chr19 12457118 12457168 chr19 12582109 12582159 chr19 1363620213636252 chr19 14608060 14608110 chr19 18374953 18375003 chr19 1967550919675559 chr19 19927249 19927299 chr19 19928049 19928099 chr19 2005394620053996 chr19 22550554 22550604 chr19 39014444 39014494 chr19 3909715739097207 chr19 39210799 39210849 chr19 39298718 39298768 chr19 4010406540104115 chr19 40312519 40312569 chr19 41416208 41416258 chr19 4198344441983494 chr19 42297826 42297876 chr19 42434816 42434866 chr19 4292737242927422 chr19 43051386 43051436 chr19 43814405 43814455 chr19 4466184444661894 chr19 45157085 45157135 chr19 46020142 46020192 chr19 4722457047224620 chr19 48096167 48096217 chr19 48528031 48528081 chr19 4947694249476992 chr19 49790227 49790277 chr19 50064723 50064773 chr19 5006494150064991 chr19 54023193 54023243 chr19 54084423 54084473 chr19 5412885654128906 chr19 54409083 54409133 chr19 54572471 54572521 chr19 5457366254573712 chr19 54912714 54912764 chr19 55201725 55201775 chr19 5585024755850297 chr10 112819591 112819641 chr19 56990359 56990409 chr1956990162 56990212 chr19 57101744 57101794 chr19 57223274 57223324 chr1957534103 57534153 chr19 57583805 57583855 chr19 57678883 57678933 chr1957715328 57715378 chr19 57936032 57936082 chr19 58067902 58067952 chr1958131094 58131144 chr19 58139364 58139414 chr19 58139848 58139898 chr1958524305 58524355 chr19 58655200 58655250 chr19 58663290 58663340 chr1958693704 58693754 chr19 60147270 60147320 chr19 60264098 60264148 chr1960921908 60921958 chr19 61889467 61889517 chr19 62908476 62908526 chr1962979314 62979364 chr19 63014267 63014317 chr19 63041136 63041186 chr1963081082 63081132 chr1 4082911 4082961 chr1 8772419 8772469 chr1 97684729768522 chr1 9922438 9922488 chr1 10197485 10197535 chr1 1166059611660646 chr1 14824498 14824548 chr1 16841185 16841235 chr1 1689924116899291 chr1 16898581 16898631 chr1 24164941 24164991 chr1 2482045524820505 chr1 25518926 25518976 chr1 26741394 26741444 chr1 2935201029352060 chr1 29374465 29374515 chr10 6308540 6308590 chr1 3050596130506011 chr1 30875004 30875054 chr1 31132939 31132989 chr1 3242125332421303 chr1 34925638 34925688 chr10 121231194 121231244 chr1 3889329138893341 chr1 39594422 39594472 chr1 40452176 40452226 chr1 5086785450867904 chr10 123353996 123354046 chr10 124214281 124214331 chr170297151 70297201 chr1 72392831 72392881 chr1 79591418 79591468 chr187979260 87979310 chr1 88999425 88999475 chr1 89000532 89000582 chr191136245 91136295 chr1 99722492 99722542 chr1 99764281 99764331 chr10125933926 125933976 chr10 6878733 6878783 chr1 109607654 109607704 chr1109609184 109609234 chr1 109704713 109704763 chr1 142422815 142422865chr1 143848963 143849013 chr1 144219839 144219889 chr1 149644103149644153 chr10 127203590 127203640 chr1 157877337 157877387 chr1158133402 158133452 chr1 158502271 158502321 chr1 158599498 158599548chr10 530890 530940 chr1 163766609 163766659 chr1 166138524 166138574chr1 170683770 170683820 chr1 179933430 179933480 chr1 184282640184282690 chr1 185214345 185214395 chr1 210113833 210113883 chr1210268275 210268325 chr1 225300517 225300567 chr1 232206612 232206662chr1 236392854 236392904 chr10 132083157 132083207 chr10 132158267132158317 chr1 243193452 243193502 chr20 4078369 4078419 chr20 40805024080552 chr20 4082818 4082868 chr20 5724614 5724664 chr20 58608955860945 chr20 11386842 11386892 chr20 14508301 14508351 chr20 1460754614607596 chr10 133294432 133294482 chr20 20871044 20871094 chr2022982692 22982742 chr20 36282036 36282086 chr20 37267363 37267413 chr2037268504 37268554 chr20 45783368 45783418 chr20 47194089 47194139 chr2049811822 49811872 chr10 134140180 134140230 chr20 53116671 53116721chr20 54833663 54833713 chr20 62620801 62620851 chr20 63017220 63017270chr20 63018381 63018431 chr21 14575322 14575372 chr11 177578 177628chr11 191665 191715 chr21 17960114 17960164 chr21 17988104 17988154chr21 18418060 18418110 chr21 26125060 26125110 chr21 33290009 33290059chr21 37536121 37536171 chr21 37535965 37536015 chr21 37823869 37823919chr21 41713057 41713107 chr21 41714151 41714201 chr21 43461083 43461133chr21 44558906 44558956 chr21 44928959 44929009 chr22 15773725 15773775chr22 15915572 15915622 chr22 15914400 15914450 chr22 16538232 16538282chr22 17266672 17266722 chr22 19773175 19773225 chr22 22203765 22203815chr22 22573782 22573832 chr22 22574875 22574925 chr22 22623362 22623412chr22 30888012 30888062 chr22 30936393 30936443 chr22 32255216 32255266chr22 34619426 34619476 chr22 34848163 34848213 chr22 34934904 34934954chr22 37651766 37651816 chr11 2456544 2456594 chr22 40350458 40350508chr22 45121278 45121328 chr22 48338196 48338246 chr11 3441612 3441662chrX 2435691 2435741 chrX 4916362 4916412 chr10 10581271 10581321 chrX18360369 18360419 chr11 5071229 5071279 chrX 22687586 22687636 chrX25598216 25598266 chrX 30001173 30001223 chrX 37680962 37681012 chrX39219479 39219529 chrX 40325645 40325695 chrX 43457122 43457172 chrX43622446 43622496 chrX 50318105 50318155 chrX 50474127 50474177 chrX54829011 54829061 chrX 56576723 56576773 chrX 56912124 56912174 chrX60828851 60828901 chrX 61595332 61595382 chrX 62389251 62389301 chrX70820814 70820864 chrX 76112402 76112452 chrX 85999669 85999719 chrX86586306 86586356 chrX 90186963 90187013 chrX 106392702 106392752 chrX112966741 112966791 chr11 10178787 10178837 chrX 120574243 120574293chrX 121949911 121949961 chrX 123239105 123239155 chrX 128110094128110144 chrX 132777701 132777751 chrX 136122200 136122250 chrX147342261 147342311 chrX 147345673 147345723 chrX 147681116 147681166chrX 150826296 150826346 chrY 14224373 14224423 chr2 803011 803061 chr21386924 1386974 chr2 1386770 1386820 chr2 1653587 1653637 chr2 75909387590988 chr2 7590758 7590808 chr2 8855284 8855334 chr2 10375995 10376045chr2 14721153 14721203 chr2 20542197 20542247 chr11 18303058 18303108chr2 26213571 26213621 chr2 26948363 26948413 chr2 27367431 27367481chr2 30293756 30293806 chr2 32476162 32476212 chr2 33276483 33276533chr2 35009255 35009305 chr2 38480197 38480247 chr2 43051909 43051959chr2 47968310 47968360 chr2 54520656 54520706 chr11 22936248 22936298chr11 23078326 23078376 chr2 62129354 62129404 chr2 62629146 62629196chr2 64271607 64271657 chr2 73321932 73321982 chr2 76030916 76030966chr2 86019756 86019806 chr2 86019989 86020039 chr2 89068246 89068296chr2 91236795 91236845 chr2 105748503 105748553 chr2 113527152 113527202chr2 113787792 113787842 chr2 114612118 114612168 chr2 120233747120233797 chr2 120382380 120382430 chr2 122028884 122028934 chr2128302671 128302721 chr2 128777913 128777963 chr2 131890722 131890772chr2 133227915 133227965 chr2 135936087 135936137 chr2 142367141142367191 chr2 153086980 153087030 chr2 154890591 154890641 chr2162226587 162226637 chr2 167164919 167164969 chr2 181977849 181977899chr2 187588348 187588398 chr2 199868786 199868836 chr2 199944855199944905 chr2 201899765 201899815 chr2 202207405 202207455 chr2204125383 204125433 chr2 219163193 219163243 chr2 221389386 221389436chr2 228789477 228789527 chr2 229435141 229435191 chr2 230248061230248111 chr2 231240337 231240387 chr2 231240075 231240125 chr2232645112 232645162 chr2 232710689 232710739 chr2 233460964 233461014chr2 235569011 235569061 chr2 238710706 238710756 chr3 5097995 5098045chr3 5099285 5099335 chr3 9663170 9663220 chr3 9870157 9870207 chr312748811 12748861 chr3 23452238 23452288 chr11 47760530 47760580 chr338137127 38137177 chr3 38138628 38138678 chr3 39421348 39421398 chr339780790 39780840 chr3 42868634 42868684 chr3 43261356 43261406 chr344435106 44435156 chr3 44514297 44514347 chr3 45758782 45758832 chr346081060 46081110 chr3 48115327 48115377 chr11 55560301 55560351 chr365803559 65803609 chr3 71949171 71949221 chr3 72058973 72059023 chr375363945 75363995 chr3 75521334 75521384 chr3 81050160 81050210 chr1158678998 58679048 chr11 58680134 58680184 chr3 97591732 97591782 chr3100459853 100459903 chr3 101376436 101376486 chr3 105532960 105533010chr11 59918930 59918980 chr3 111407124 111407174 chr3 114075108114075158 chr3 114880044 114880094 chr11 60255915 60255965 chr1160302788 60302838 chr3 125782712 125782762 chr3 126931118 126931168 chr3129731695 129731745 chr11 60924835 60924885 chr3 131098184 131098234chr3 131162886 131162936 chr3 131162790 131162840 chr3 147561904147561954 chr3 152718256 152718306 chr3 157121064 157121114 chr1161738520 61738570 chr11 61870485 61870535 chr11 61914174 61914224 chr1161925022 61925072 chr3 178363070 178363120 chr3 180532846 180532896 chr3181796123 181796173 chr3 184560025 184560075 chr11 62403018 62403068chr3 188263334 188263384 chr3 196025398 196025448 chr3 197658103197658153 chr3 198989054 198989104 chr4 226019 226069 chr4 19854421985492 chr4 2759844 2759894 chr4 3354055 3354105 chr4 3353869 3353919chr4 3689621 3689671 chr4 4043501 4043551 chr4 4052072 4052122 chr45827767 5827817 chr11 64114644 64114694 chr4 9503863 9503913 chr49879847 9879897 chr11 64566820 64566870 chr4 29986235 29986285 chr434395984 34396034 chr4 35477560 35477610 chr4 40159666 40159716 chr440800479 40800529 chr4 48203041 48203091 chr4 60345528 60345578 chr465225603 65225653 chr4 69150697 69150747 chr4 78482962 78483012 chr483293080 83293130 chr4 89881624 89881674 chr4 97374024 97374074 chr497904176 97904226 chr4 109108881 109108931 chr4 130089597 130089647 chr4136918281 136918331 chr4 146139065 146139115 chr4 157885104 157885154chr10 13686047 13686097 chr4 162157466 162157516 chr10 13685834 13685884chr4 163918000 163918050 chr4 166520004 166520054 chr4 166572656166572706 chr4 167592424 167592474 chr4 173599653 173599703 chr4176018754 176018804 chr4 183347153 183347203 chr4 185343383 185343433chr4 186743116 186743166 chr4 188512088 188512138 chr4 188984139188984189 chr4 190556677 190556727 chr4 190972775 190972825 chr4191131919 191131969 chr5 250030 250080 chr5 1648794 1648844 chr5 18608201860870 chr5 2955624 2955674 chr5 4977684 4977734 chr5 10254793 10254843chr5 10254521 10254571 chr5 11315236 11315286 chr5 16676943 16676993chr5 18156976 18157026 chr5 19367338 19367388 chr5 21337684 21337734chr5 37717404 37717454 chr5 38816080 38816130 chr5 42967259 42967309chr5 43021322 43021372 chr5 55339846 55339896 chr5 55469507 55469557chr5 76936282 76936332 chr5 78289643 78289693 chr5 78969219 78969269chr5 79491046 79491096 chr5 79491922 79491972 chr11 70912291 70912341chr5 92187827 92187877 chr5 92867637 92867687 chr5 105671781 105671831chr5 105739154 105739204 chr11 71624551 71624601 chr11 71624085 71624135chr11 71624161 71624211 chr5 118476844 118476894 chr11 72232937 72232987chr5 130301407 130301457 chr5 131697694 131697744 chr5 132218624132218674 chr5 133709258 133709308 chr11 73068908 73068958 chr5141669062 141669112 chr5 149173636 149173686 chr5 153565323 153565373chr5 154045071 154045121 chr5 154101609 154101659 chr5 156075016156075066 chr5 159610319 159610369 chr5 159737184 159737234 chr5161114538 161114588 chr5 163845088 163845138 chr10 14752833 14752883chr5 169017888 169017938 chr5 169756391 169756441 chr5 171467209171467259 chr5 172586454 172586504 chr5 174982399 174982449 chr5177596414 177596464 chr5 179758671 179758721 chr5 180365018 180365068chr5 180659178 180659228 chr5 180803497 180803547 chr6 2524571 2524621chr6 2854841 2854891 chr6 5585635 5585685 chr6 5585498 5585548 chr610574982 10575032 chr6 10693170 10693220 chr6 19785228 19785278 chr1180225328 80225378 chr6 22581376 22581426 chr6 24770751 24770801 chr625629663 25629713 chr6 26313993 26314043 chr6 26864200 26864250 chr627672853 27672903 chr6 27901757 27901807 chr6 28759257 28759307 chr628763699 28763749 chr6 28945433 28945483 chr6 28946011 28946061 chr632555394 32555444 chr6 33580245 33580295 chr6 35344242 35344292 chr636649234 36649284 chr6 37367387 37367437 chr6 42909285 42909335 chr642917246 42917296 chr6 44775175 44775225 chr6 64832193 64832243 chr669185129 69185179 chr11 90428685 90428735 chr6 78431752 78431802 chr683084521 83084571 chr11 91901264 91901314 chr6 90596642 90596692 chr1193343104 93343154 chr6 110222353 110222403 chr6 110228704 110228754 chr6111185814 111185864 chr6 111408743 111408793 chr6 127541536 127541586chr6 135380018 135380068 chr6 135634057 135634107 chr6 151533824151533874 chr6 153016984 153017034 chr11 100636870 100636920 chr11101103329 101103379 chr6 159399357 159399407 chr6 160413126 160413176chr6 160414437 160414487 chr6 162298701 162298751 chr11 102791860102791910 chr6 165823852 165823902 chr11 102927867 102927917 chr11102935242 102935292 chr6 166853530 166853580 chr6 170650606 170650656chr7 1859001 1859051 chr7 4752613 4752663 chr7 5368745 5368795 chr721190287 21190337 chr7 22234162 22234212 chr7 23196919 23196969 chr723539081 23539131 chr7 27524638 27524688 chr7 32297009 32297059 chr732313423 32313473 chr7 44637395 44637445 chr7 47770789 47770839 chr749411593 49411643 chr7 50991381 50991431 chr7 50991154 50991204 chr765495540 65495590 chr7 74994612 74994662 chr7 96559666 96559716 chr798641772 98641822 chr7 100680721 100680771 chr11 117681634 117681684chr7 112338636 112338686 chr7 116070953 116071003 chr7 130411018130411068 chr11 118447704 118447754 chr7 136415656 136415706 chr7136980756 136980806 chr7 136980696 136980746 chr7 137891411 137891461chr7 139660490 139660540 chr7 140863241 140863291 chr7 148156215148156265 chr7 148774038 148774088 chr7 148777194 148777244 chr7150115663 150115713 chr7 150115776 150115826 chr7 151839062 151839112chr7 153639294 153639344 chr7 156133528 156133578 chr7 156304969156305019 chr7 156502968 156503018 chr8 600706 600756 chr8 50547625054812 chr8 7392473 7392523 chr8 7667950 7668000 chr8 7668627 7668677chr8 8101666 8101716 chr8 13448334 13448384 chr8 14045686 14045736 chr815273499 15273549 chr8 20651626 20651676 chr11 122688337 122688387 chr838059585 38059635 chr8 47359859 47359909 chr8 50364187 50364237 chr852962599 52962649 chr8 53727703 53727753 chr8 59634378 59634428 chr859635828 59635878 chr8 60104683 60104733 chr8 62813507 62813557 chr874147741 74147791 chr8 94534426 94534476 chr8 98818862 98818912 chr8100912384 100912434 chr8 103399565 103399615 chr8 107546488 107546538chr8 113432643 113432693 chr8 120886933 120886983 chr8 127261747127261797 chr8 129953432 129953482 chr8 134532339 134532389 chr8134532409 134532459 chr8 140034628 140034678 chr8 140200399 140200449chr8 144469340 144469390 chr8 146083556 146083606 chr8 146180661146180711 chr8 146257865 146257915 chr9 6085716 6085766 chr9 66863386686388 chr9 26705109 26705159 chr9 30678947 30678997 chr9 4060839040608440 chr9 71159213 71159263 chr9 73352841 73352891 chr9 7466559574665645 chr9 75105168 75105218 chr9 79383344 79383394 chr9 8243989882439948 chr9 89417021 89417071 chr9 90957962 90958012 chr9 9337397693374026 chr9 94514620 94514670 chr9 94515309 94515359 chr9 111348528111348578 chr9 111518356 111518406 chr9 112717357 112717407 chr9125035429 125035479 chr9 126811035 126811085 chr9 126995797 126995847chr9 129509269 129509319 chr9 135033112 135033162 chr9 135049672135049722 chr9 135369186 135369236 chr12 5516406 5516456 chr12 67782196778269 chr12 6866209 6866259 chr12 7692419 7692469 chr12 82639988264048 chr12 8680450 8680500 chr12 9855911 9855961 chr12 1061510310615153 chr12 12977866 12977916 chr12 14348933 14348983 chr12 2011728820117338 chr12 21689893 21689943 chr12 27818870 27818920 chr12 3425979534259845 chr12 34259704 34259754 chr12 40423906 40423956 chr12 4101115041011200 chr12 41068802 41068852 chr12 49805389 49805439 chr12 4980548149805531 chr12 51192764 51192814 chr12 54748754 54748804 chr12 5550315255503202 chr12 57016996 57017046 chr12 59869047 59869097 chr12 6620837166208421 chr12 67362124 67362174 chr12 67837052 67837102 chr12 7168873571688785 chr10 28878208 28878258 chr12 84365534 84365584 chr12 8541420785414257 chr12 89271681 89271731 chr12 89669396 89669446 chr12 9177640891776458 chr12 91970617 91970667 chr12 95771213 95771263 chr10 12934161293466 chr10 32653876 32653926 chr12 121673137 121673187 chr12123029942 123029992 chr12 126057309 126057359 chr12 127061202 127061252chr12 127492584 127492634 chr12 127727856 127727906 chr10 3495132834951378 chr10 35065409 35065459 chr10 35390026 35390076 chr13 1829437018294420 chr13 18493512 18493562 chr13 18944891 18944941 chr13 1977610219776152 chr13 19849293 19849343 chr13 21185979 21186029 chr13 2631185326311903 chr13 41412887 41412937 chr13 47972108 47972158 chr13 5263904052639090 chr13 61237284 61237334 chr13 65366572 65366622 chr13 6617117266171222 chr13 68851070 68851120 chr13 69562460 69562510 chr13 7309183173091881 chr13 78143115 78143165 chr13 86205023 86205073 chr10 4311770743117757 chr13 93619085 93619135 chr13 95850463 95850513 chr13 9640492296404972 chr10 43231649 43231699 chr10 43231302 43231352 chr10 4354023543540285 chr13 108796648 108796698 chr13 110546628 110546678 chr13111609992 111610042 chr13 111611289 111611339 chr13 111982820 111982870chr13 112385790 112385840 chr13 112865395 112865445 chr14 2246956622469616 chr14 24252092 24252142 chr14 36822964 36823014 chr14 4874520348745253 chr14 49011794 49011844 chr14 51200028 51200078 chr14 5320912653209176 chr10 50899856 50899906 chr14 68991832 68991882 chr14 6899171668991766 chr14 69625718 69625768 chr14 71485098 71485148 chr14 7609137676091426 chr14 76117748 76117798 chr14 76152163 76152213 chr14 8200411882004168 chr14 85477331 85477381 chr14 88283794 88283844 chr14 9308245093082500 chr14 93082268 93082318 chr14 94900977 94901027 chr14 101472452101472502 chr14 101889761 101889811 chr14 103661657 103661707 chr14103711185 103711235 chr14 104171193 104171243 chr15 23816087 23816137chr15 24614617 24614667 chr15 26142158 26142208 chr15 27557906 27557956chr15 39623078 39623128 chr15 42808318 42808368 chr15 51492229 51492279chr15 68383158 68383208 chr15 71182443 71182493 chr10 68955555 68955605chr15 72894311 72894361 chr15 76229398 76229448 chr15 76229450 76229500chr15 79444909 79444959 chr15 82552541 82552591 chr15 89247277 89247327chr15 100135410 100135460 chr16 799691 799741 chr16 1465411 1465461chr16 3093650 3093700 chr16 3550533 3550583 chr10 3057865 3057915 chr1610396311 10396361 chr16 17738062 17738112 chr16 18937337 18937387 chr1621054833 21054883 chr16 21193947 21193997 chr16 25043347 25043397 chr1648243212 48243262 chr16 64233038 64233088 chr16 68134896 68134946 chr1668134692 68134742 chr16 75628703 75628753 chr16 83692170 83692220 chr1684715560 84715610 chr16 89027035 89027085 chr16 89051255 89051305 chr1689859686 89859736 chr17 1928094 1928144 chr10 76313405 76313455 chr1076313622 76313672 chr10 76314057 76314107 chr17 2985591 2985641 chr176279672 6279722 chr17 6751001 6751051 chr17 6976142 6976192 chr178429697 8429747 chr17 9563207 9563257 chr17 11194088 11194138 chr1711218555 11218605 chr17 11711370 11711420 chr17 15376515 15376565 chr1715375773 15375823 chr17 15582313 15582363 chr17 15582374 15582424 chr1719570267 19570317 chr17 19585172 19585222 chr17 29067387 29067437 chr1729173707 29173757 chr17 30329244 30329294 Table 15BF. Repeat CategoryLTR51 chr19 14608060 14608110 chr19 39097157 39097207 chr1 97684729768522 chr1 16899241 16899291 chr1 16898581 16898631 chr10 530890530940 chr20 37267363 37267413 chr20 37268504 37268554 chr20 5311667153116721 chr21 37823869 37823919 chr22 30936393 30936443 chrX 49163624916412 chr2 142367141 142367191 chr4 183347153 183347203 chr4 186743116186743166 chr5 92187827 92187877 chr11 71624551 71624601 chr11 7162408571624135 chr11 71624161 71624211 chr11 72232937 72232987 chr5 133709258133709308 chr10 14752833 14752883 chr5 174982399 174982449 chr6 2562966325629713 chr6 26313993 26314043 chr6 35344242 35344292 chr6 6918512969185179 chr7 49411593 49411643 chr12 9855911 9855961 chr12 1297786612977916 chr12 127061202 127061252 chr13 95850463 95850513 chr1523816087 23816137 chr16 18937337 18937387 Table 15BG. Repeat CategoryLTR52 chr17 41916256 41916306 chr17 42159421 42159471 chr17 4721082947210879 chr17 47213443 47213493 chr17 47215152 47215202 chr17 5317608953176139 chr18 26785077 26785127 chr18 63999808 63999858 chr10 100731341100731391 chr19 12173944 12173994 chr19 12229801 12229851 chr19 1223226112232311 chr19 12457118 12457168 chr19 12582109 12582159 chr19 1967550919675559 chr19 42927372 42927422 chr19 55201725 55201775 chr10 112819591112819641 chr19 57583805 57583855 chr1 30505961 30506011 chr1 3889329138893341 chr20 4078369 4078419 chr20 4080502 4080552 chr20 40828184082868 chr22 48338196 48338246 chrX 2435691 2435741 chrX 5047412750474177 chrX 120574243 120574293 chrX 123239105 123239155 chrX128110094 128110144 chr2 14721153 14721203 chr2 76030916 76030966 chr2153086980 153087030 chr2 231240337 231240387 chr2 231240075 231240125chr3 72058973 72059023 chr3 105532960 105533010 chr3 114880044 114880094chr4 35477560 35477610 chr4 89881624 89881674 chr4 97374024 97374074chr4 166520004 166520054 chr4 188984139 188984189 chr5 76936282 76936332chr5 105739154 105739204 chr6 64832193 64832243 chr6 83084521 83084571chr11 100636870 100636920 chr7 4752613 4752663 chr8 5054762 5054812 chr813448334 13448384 chr8 50364187 50364237 chr8 113432643 113432693 chr930678947 30678997 chr9 90957962 90958012 chr12 40423906 40423956 chr1251192764 51192814 chr12 85414207 85414257 chr13 66171172 66171222 chr1368851070 68851120 chr13 69562460 69562510 chr13 78143115 78143165 chr1043231649 43231699 chr10 43231302 43231352 chr15 24614617 24614667 chr163093650 3093700 chr16 64233038 64233088 chr17 15582313 15582363 chr1715582374 15582424 Table 15BH. Repeat Category LTR54B chr17 3821262938212679 chr17 38950887 38950937 chr19 11583758 11583808 chr19 1209989612099946 chr19 39210799 39210849 chr19 48096167 48096217 chr1 179933430179933480 chr1 210113833 210113883 chr1 210268275 210268325 chr1225300517 225300567 chr20 14508301 14508351 chr20 14607546 14607596chr11 177578 177628 chr22 30888012 30888062 chr11 5071229 5071279 chrX30001173 30001223 chrX 40325645 40325695 chrX 43622446 43622496 chrX86586306 86586356 chrX 90186963 90187013 chrX 132777701 132777751 chrX147681116 147681166 chr2 133227915 133227965 chr2 235569011 235569061chr3 44514297 44514347 chr3 65803559 65803609 chr3 129731695 129731745chr4 78482962 78483012 chr5 2955624 2955674 chr5 11315236 11315286 chr578969219 78969269 chr5 159610319 159610369 chr5 159737184 159737234 chr5163845088 163845138 chr6 2524571 2524621 chr6 22581376 22581426 chr6110228704 110228754 chr11 102927867 102927917 chr7 96559666 96559716chr7 100680721 100680771 chr9 6686338 6686388 chr9 89417021 89417071chr12 34259795 34259845 chr12 34259704 34259754 chr12 67362124 67362174chr12 95771213 95771263 chr13 18493512 18493562 chr14 51200028 51200078chr14 101889761 101889811 chr15 27557906 27557956 chr16 3550533 3550583chr16 21054833 21054883 chr16 84715560 84715610 Table 15BI. RepeatCategory LTR56 chr17 58087489 58087539 chr10 86582408 86582458 chr1773229072 73229122 chr18 33032404 33032454 chr18 33036041 33036091 chr1950064723 50064773 chr19 50064941 50064991 chr19 54023193 54023243 chr116841185 16841235 chr10 124214281 124214331 chr1 91136245 91136295 chr1109704713 109704763 chr1 142422815 142422865 chr1 236392854 236392904chr10 133294432 133294482 chr20 20871044 20871094 chr10 134140180134140230 chr21 37536121 37536171 chr21 37535965 37536015 chr22 1726667217266722 chrX 61595332 61595382 chrX 76112402 76112452 chr2 16535871653637 chr11 18303058 18303108 chr2 47968310 47968360 chr2 6262914662629196 chr2 64271607 64271657 chr2 114612118 114612168 chr2 120382380120382430 chr2 131890722 131890772 chr2 162226587 162226637 chr2232710689 232710739 chr3 46081060 46081110 chr3 71949171 71949221 chr3125782712 125782762 chr11 60924835 60924885 chr3 152718256 152718306chr4 2759844 2759894 chr4 3689621 3689671 chr4 40159666 40159716 chr4191131919 191131969 chr5 19367338 19367388 chr5 55339846 55339896 chr5118476844 118476894 chr11 73068908 73068958 chr5 154101609 154101659chr6 5585635 5585685 chr6 5585498 5585548 chr6 44775175 44775225 chr6111185814 111185864 chr7 5368745 5368795 chr7 32313423 32313473 chr750991381 50991431 chr7 50991154 50991204 chr7 130411018 130411068 chr7137891411 137891461 chr7 148774038 148774088 chr7 148777194 148777244chr7 151839062 151839112 chr8 20651626 20651676 chr8 59635828 59635878chr8 62813507 62813557 chr8 140200399 140200449 chr9 40608390 40608440chr9 94514620 94514670 chr9 94515309 94515359 chr9 126811035 126811085chr12 7692419 7692469 chr12 20117288 20117338 chr12 54748754 54748804chr10 32653876 32653926 chr10 35065409 35065459 chr13 18294370 18294420chr13 18944891 18944941 chr13 111982820 111982870 chr13 112385790112385840 chr14 103661657 103661707 chr15 72894311 72894361 chr161465411 1465461 chr16 10396311 10396361 chr16 21193947 21193997 chr172985591 2985641 chr17 8429697 8429747 Table 15BJ. Repeat Category LTR5Achr19 58524305 58524355 chr19 60264098 60264148 chr22 15915572 15915622chr22 15914400 15914450 chr11 3441612 3441662 chr11 23078326 23078376chr2 135936087 135936137 chr3 75521334 75521384 chr3 131162886 131162936chr3 131162790 131162840 chr4 4043501 4043551 chr4 4052072 4052122 chr49503863 9503913 chr4 29986235 29986285 chr4 157885104 157885154 chr4185343383 185343433 chr5 250030 250080 chr5 154045071 154045121 chr6160413126 160413176 chr6 160414437 160414487 chr8 7392473 7392523 chr87667950 7668000 chr8 7668627 7668677 chr8 8101666 8101716 chr11122688337 122688387 chr8 47359859 47359909 chr8 146257865 146257915chr12 8263998 8264048 chr12 55503152 55503202 chr13 112865395 112865445chr14 22469566 22469616 chr14 53209126 53209176 chr14 93082450 93082500chr14 93082268 93082318 Table 15BK. Repeat Category LTR65 chr17 5867929658679346 chr19 2366379 2366429 chr19 47054260 47054310 chr19 5346825653468306 chr1 29924046 29924096 chr1 147063494 147063544 chr1 233536900233536950 chr20 30778714 30778764 chr20 55704857 55704907 chr11 46622214662271 chrX 46268177 46268227 chr2 37398453 37398503 chr2 3739886337398913 chr2 101578855 101578905 chr3 111395145 111395195 chr1162385503 62385553 chr4 68572670 68572720 chr6 24755917 24755967 chr626546561 26546611 chr6 26546667 26546717 chr6 74081386 74081436 chr722963657 22963707 chr8 42973385 42973435 chr8 98611214 98611264 chr8124012294 124012344 chr12 63193804 63193854 chr12 108975571 108975621chr10 32350313 32350363 chr13 98944739 98944789 chr14 32956461 32956511chr16 62102874 62102924 chr17 3843718 3843768 chr17 3844580 3844630chr17 21121035 21121085 Table 15BL. Repeat Category LTR66 chr17 4252574442525794 chr17 42575356 42575406 chr17 42576034 42576084 chr19 92173269217376 chr19 19834257 19834307 chr19 20038058 20038108 chr19 2004495920045009 chr19 20125977 20126027 chr10 121195738 121195788 chr1111132469 111132519 chr1 111132109 111132159 chr1 212089602 212089652chr1 223698589 223698639 chr1 223705206 223705256 chr1 223705042223705092 chr20 19627186 19627236 chr22 16142004 16142054 chrX 41513704151420 chrX 40185787 40185837 chr2 108839271 108839321 chr11 5616538156165431 chr4 262844 262894 chr4 439031 439081 chr4 187976047 187976097chr5 40875544 40875594 chr5 99999729 99999779 chr8 27970116 27970166chr8 51820559 51820609 chr9 21971252 21971302 chr11 133048199 133048249chr9 86137877 86137927 chr9 86137286 86137336 chr9 110878440 110878490chr12 63200484 63200534 chr12 125738149 125738199 chr13 8855610088556150 chr14 80803824 80803874 chr14 101717064 101717114 chr1620720540 20720590 chr16 20721230 20721280 chr16 23721734 23721784 chr1629044602 29044652 chr16 75369771 75369821 chr16 75370295 75370345 Table15BM. Repeat Category LTR6A chr17 76865531 76865581 chr17 8081188880811938 chr17 80848148 80848198 chr10 93457709 93457759 chr19 66072936607343 chr19 6612172 6612222 chr19 17387418 17387468 chr19 2033439020334440 chr19 21671956 21672006 chr19 21831147 21831197 chr19 3817898538179035 chr19 54025367 54025417 chr19 55945378 55945428 chr19 6155022661550276 chr19 63090568 63090618 chr19 63457951 63458001 chr19 6345780863457858 chr1 32779858 32779908 chr1 89131112 89131162 chr1 8913120089131250 chr1 89131276 89131326 chr1 141306950 141307000 chr1 228382395228382445 chr21 14152879 14152929 chr21 14191313 14191363 chr21 4328329943283349 chr22 23979345 23979395 chr22 28153185 28153235 chrX 8573120485731254 chrX 85731111 85731161 chrY 7402638 7402688 chrY 95532059553255 chrY 13599141 13599191 chr2 35376023 35376073 chr2 9794975497949804 chr2 97950249 97950299 chr2 97950616 97950666 chr2 111541407111541457 chr2 113704633 113704683 chr2 232965021 232965071 chr347844896 47844946 chr3 75657517 75657567 chr3 129716285 129716335 chr3180719847 180719897 chr3 187936483 187936533 chr5 79491046 79491096 chr5179149670 179149720 chr6 2935949 2935999 chr6 68885928 68885978 chr11107242740 107242790 chr7 101534025 101534075 chr7 133649977 133650027chr8 30009411 30009461 chr8 98747519 98747569 chr9 86396222 86396272chr9 86396456 86396506 chr9 123333858 123333908 chr9 125606080 125606130chr9 135241528 135241578 chr12 9452497 9452547 chr12 18240111 18240161chr13 19333225 19333275 chr10 38228378 38228428 chr10 54059815 54059865chr10 54059971 54060021 chr10 54060368 54060418 chr14 101831459101831509 chr14 104634957 104635007 chr14 104963949 104963999 chr1543480475 43480525 chr16 10322351 10322401 chr16 35631024 35631074 chr1689422025 89422075 Table 15BN. Repeat Category LTR6B chr19 81738098173859 chr19 20229475 20229525 chr19 41513125 41513175 chr19 5896954558969595 chr19 63033640 63033690 chr1 69148146 69148196 chr1 9988855899888608 chr20 46514718 46514768 chr21 40869833 40869883 chr21 4202028442020334 chr21 42020433 42020483 chr21 42391390 42391440 chr21 4239146242391512 chrX 2404210 2404260 chrX 101411671 101411721 chrY 70235327023582 chr2 47899899 47899949 chr2 124544225 124544275 chr2 202193112202193162 chr2 212659410 212659460 chr3 75476646 75476696 chr3 126872281126872331 chr3 131223375 131223425 chr3 147450182 147450232 chr3165380052 165380102 chr3 188049743 188049793 chr4 9352921 9352971 chr1167424875 67424925 chr11 67431729 67431779 chr4 177090399 177090449 chr76779170 6779220 chr7 138190863 138190913 chr8 6992924 6992974 chr817040286 17040336 chr8 17040150 17040200 chr8 42705163 42705213 chr8138002465 138002515 chr8 145925947 145925997 chr12 22745308 22745358chr13 67835085 67835135 chr14 100521088 100521138 chr15 8681169786811747 chr15 86819392 86819442 chr16 87599119 87599169 Table 15BO.Repeat Category LTR7 chr17 41458920 41458970 chr17 53570257 53570307chr17 54019740 54019790 chr17 58109200 58109250 chr17 63705550 63705600chr17 65970811 65970861 chr17 75204469 75204519 chr17 78931863 78931913chr17 79074224 79074274 chr10 91725026 91725076 chr10 92237746 92237796chr10 92769228 92769278 chr18 11668056 11668106 chr18 14117968 14118018chr18 19122011 19122061 chr18 27658717 27658767 chr18 28113604 28113654chr18 31048632 31048682 chr18 31193724 31193774 chr10 96653888 96653938chr10 96655229 96655279 chr18 38574279 38574329 chr18 48585619 48585669chr18 52232209 52232259 chr18 60497901 60497951 chr18 69141295 69141345chr18 73753954 73754004 chr10 98986394 98986444 chr18 74397382 74397432chr19 320411 320461 chr10 5472459 5472509 chr19 2163171 2163221 chr192852265 2852315 chr19 5797840 5797890 chr19 5808683 5808733 chr1910005395 10005445 chr19 12341118 12341168 chr19 12342474 12342524 chr1912543359 12543409 chr19 15801176 15801226 chr19 15801049 15801099 chr10103244268 103244318 chr19 17869895 17869945 chr10 103617621 103617671chr19 20003389 20003439 chr19 20238122 20238172 chr19 21291041 21291091chr19 21841739 21841789 chr19 22408793 22408843 chr19 22420613 22420663chr19 23000189 23000239 chr19 23000636 23000686 chr19 23554551 23554601chr19 33618498 33618548 chr19 33618447 33618497 chr19 39696735 39696785chr19 40787816 40787866 chr19 41442157 41442207 chr19 42019143 42019193chr19 42617725 42617775 chr19 44723633 44723683 chr19 45157085 45157135chr10 107447434 107447484 chr19 51473497 51473547 chr10 110023910110023960 chr10 110987213 110987263 chr19 52244705 52244755 chr1952587809 52587859 chr19 52593911 52593961 chr19 52594048 52594098 chr1957373376 57373426 chr19 57823038 57823088 chr19 59032669 59032719 chr1959441078 59441128 chr19 59441135 59441185 chr19 59596809 59596859 chr1959748223 59748273 chr19 60215651 60215701 chr19 60332108 60332158 chr1962966742 62966792 chr1 4775024 4775074 chr10 117904962 117905012 chr112700193 12700243 chr1 13249804 13249854 chr1 16604266 16604316 chr120408931 20408981 chr1 23170475 23170525 chr1 25842410 25842460 chr140838589 40838639 chr1 41704211 41704261 chr1 42075344 42075394 chr10122004355 122004405 chr1 48050121 48050171 chr1 53285438 53285488 chr10123345115 123345165 chr1 54858123 54858173 chr1 57579138 57579188 chr158539268 58539318 chr1 64191436 64191486 chr1 64973506 64973556 chr164981409 64981459 chr1 65478775 65478825 chr1 65483613 65483663 chr168221505 68221555 chr1 68227690 68227740 chr1 72821073 72821123 chr172829291 72829341 chr1 73207164 73207214 chr1 74230932 74230982 chr181961181 81961231 chr1 83947197 83947247 chr10 6675476 6675526 chr191510808 91510858 chr1 94595290 94595340 chr10 6848897 6848947 chr1108362484 108362534 chr1 112661402 112661452 chr1 113878663 113878713chr1 116751098 116751148 chr1 116924916 116924966 chr1 144219839144219889 chr1 145434524 145434574 chr1 145504231 145504281 chr1146555801 146555851 chr1 146586234 146586284 chr1 146729526 146729576chr1 149094901 149094951 chr1 170333388 170333438 chr1 178129472178129522 chr1 180821684 180821734 chr1 183156718 183156768 chr1183162799 183162849 chr1 184973575 184973625 chr1 184979006 184979056chr1 190237348 190237398 chr1 193472613 193472663 chr1 200259625200259675 chr1 207440302 207440352 chr1 210138031 210138081 chr1210144500 210144550 chr1 212640042 212640092 chr1 212645171 212645221chr1 213237948 213237998 chr1 213243798 213243848 chr1 213382532213382582 chr1 219208696 219208746 chr1 220253922 220253972 chr1222002013 222002063 chr1 224803468 224803518 chr1 226277275 226277325chr1 226793704 226793754 chr1 227900599 227900649 chr1 229006381229006431 chr1 229288686 229288736 chr1 229294903 229294953 chr1234142406 234142456 chr1 234693440 234693490 chr1 235337658 235337708chr1 235480380 235480430 chr1 235584318 235584368 chr1 236013819236013869 chr1 237968428 237968478 chr1 241460664 241460714 chr1243528719 243528769 chr1 243795101 243795151 chr1 243796303 243796353chr1 244189592 244189642 chr1 244470329 244470379 chr20 742482 742532chr20 4635833 4635883 chr20 12321818 12321868 chr20 12735264 12735314chr20 13338506 13338556 chr20 13876308 13876358 chr20 18492481 18492531chr20 18498196 18498246 chr20 19727641 19727691 chr20 21646042 21646092chr20 32272146 32272196 chr20 36304577 36304627 chr20 39407139 39407189chr20 39413065 39413115 chr20 42696340 42696390 chr20 43839348 43839398chr20 53701485 53701535 chr20 55854040 55854090 chr20 59976389 59976439chr20 61136928 61136978 chr21 14326082 14326132 chr21 19415400 19415450chr21 21028477 21028527 chr21 24121515 24121565 chr21 24216753 24216803chr21 26522033 26522083 chr21 30043571 30043621 chr21 37884951 37885001chr21 40990842 40990892 chr21 41246842 41246892 chr21 41253213 41253263chr21 42101473 42101523 chr21 43114939 43114989 chr21 44618204 44618254chr21 44759565 44759615 chr11 1314631 1314681 chr22 18398743 18398793chr22 18658204 18658254 chr22 19187029 19187079 chr22 19187947 19187997chr22 23412040 23412090 chr22 26462786 26462836 chr22 32555208 32555258chr22 37678648 37678698 chr22 37701491 37701541 chr22 37769940 37769990chr22 41192174 41192224 chr22 42291160 42291210 chr22 43803544 43803594chr22 44286645 44286695 chr22 46694833 46694883 chrX 3066239 3066289chrX 3103984 3104034 chrX 4276859 4276909 chrX 5687488 5687538 chrX12319325 12319375 chr11 5669400 5669450 chr11 6055258 6055308 chr116061449 6061499 chrX 29409331 29409381 chrX 29483767 29483817 chrX29834387 29834437 chrX 30757139 30757189 chrX 30762825 30762875 chrX32483243 32483293 chr11 6351533 6351583 chrX 39723070 39723120 chrX41897661 41897711 chrX 46188728 46188778 chrX 47494834 47494884 chrX69351664 69351714 chrX 72238335 72238385 chrX 85714508 85714558 chrX85715676 85715726 chrX 87611397 87611447 chrX 87613151 87613201 chrX87783484 87783534 chrX 90127018 90127068 chrX 92725642 92725692 chrX92731936 92731986 chrX 96316297 96316347 chrX 98603436 98603486 chrX100760285 100760335 chrX 101455806 101455856 chrX 107836776 107836826chrX 109550892 109550942 chrX 111187735 111187785 chrX 112054385112054435 chrX 112465245 112465295 chrX 115172922 115172972 chrX117205817 117205867 chrX 120059532 120059582 chrX 121608817 121608867chrX 123228928 123228978 chrX 123333255 123333305 chrX 132785064132785114 chrX 137701174 137701224 chrX 140204738 140204788 chrX140212967 140213017 chrX 143475247 143475297 chrY 2753777 2753827 chrY2756111 2756161 chrY 4900878 4900928 chr11 14510814 14510864 chrY19702078 19702128 chr2 20468938 20468988 chr2 22051998 22052048 chr2797109 797159 chr2 8040816 8040866 chr2 16957702 16957752 chr2 1696357916963629 chr2 17990089 17990139 chr2 27941470 27941520 chr2 3564173535641785 chr2 37025262 37025312 chr2 38590343 38590393 chr2 4422635744226407 chr2 45241595 45241645 chr11 20553729 20553779 chr2 4789989947899949 chr2 58315050 58315100 chr2 58320785 58320835 chr2 6061906460619114 chr11 23169493 23169543 chr2 64459301 64459351 chr2 6965033769650387 chr11 25472316 25472366 chr2 70822185 70822235 chr2 7082810270828152 chr2 71287939 71287989 chr2 71292495 71292545 chr2 7541536075415410 chr2 76775249 76775299 chr2 77290465 77290515 chr2 7810225478102304 chr2 78965979 78966029 chr2 81081809 81081859 chr11 2762081027620860 chr2 85266720 85266770 chr2 99848100 99848150 chr2 101416235101416285 chr11 32129805 32129855 chr11 32135280 32135330 chr2 110712182110712232 chr2 111599503 111599553 chr2 115643625 115643675 chr2138657080 138657130 chr2 138790890 138790940 chr2 154593483 154593533chr2 166766568 166766618 chr2 173232361 173232411 chr11 3776054137760591 chr2 184111025 184111075 chr2 184128127 184128177 chr2184597144 184597194 chr2 188633405 188633455 chr2 188743059 188743109chr2 189100605 189100655 chr2 189235924 189235974 chr2 189241624189241674 chr2 193197623 193197673 chr2 200319991 200320041 chr1139720435 39720485 chr2 207049639 207049689 chr2 208084452 208084502 chr2209961245 209961295 chr2 210151784 210151834 chr2 210366552 210366602chr2 210372381 210372431 chr11 42111217 42111267 chr2 216995419216995469 chr11 43974323 43974373 chr2 223915799 223915849 chr2232637365 232637415 chr2 236326913 236326963 chr2 238808029 238808079chr2 239420221 239420271 chr3 5165886 5165936 chr3 6738091 6738141 chr310747574 10747624 chr3 11287847 11287897 chr3 14288629 14288679 chr316760664 16760714 chr3 27616047 27616097 chr3 32473898 32473948 chr332479540 32479590 chr3 32809601 32809651 chr3 38085537 38085587 chr341966905 41966955 chr3 45315474 45315524 chr3 46246893 46246943 chr346246379 46246429 chr3 46558940 46558990 chr3 48232390 48232440 chr348726495 48726545 chr3 51795554 51795604 chr3 54625825 54625875 chr354631560 54631610 chr3 57295022 57295072 chr3 61635405 61635455 chr371894904 71894954 chr3 75445268 75445318 chr3 78559109 78559159 chr395868837 95868887 chr3 97249984 97250034 chr3 99284120 99284170 chr3102658141 102658191 chr3 106077332 106077382 chr3 113458126 113458176chr3 113463226 113463276 chr3 119773564 119773614 chr3 120165128120165178 chr3 125797321 125797371 chr3 125867722 125867772 chr3129874226 129874276 chr3 129881265 129881315 chr3 131104699 131104749chr3 134474740 134474790 chr3 144112238 144112288 chr3 146595058146595108 chr3 149452834 149452884 chr3 149458833 149458883 chr3150235942 150235992 chr3 153635679 153635729 chr11 61587529 61587579chr3 154264772 154264822 chr3 154271240 154271290 chr3 154867467154867517 chr3 157083847 157083897 chr3 157083481 157083531 chr3165386064 165386114 chr3 171717038 171717088 chr3 175270817 175270867chr3 177100576 177100626 chr3 177365415 177365465 chr3 178704449178704499 chr3 178709974 178710024 chr3 180555561 180555611 chr3180564544 180564594 chr3 183781376 183781426 chr3 187702397 187702447chr3 188224308 188224358 chr3 192934349 192934399 chr3 193109909193109959 chr3 193115542 193115592 chr3 196763750 196763800 chr3196763450 196763500 chr4 45068 45118 chr4 112371 112421 chr4 283783283833 chr4 324789 324839 chr4 5115780 5115830 chr4 5521949 5521999 chr46596559 6596609 chr4 13928461 13928511 chr4 16727142 16727192 chr416756591 16756641 chr4 18769231 18769281 chr4 23475191 23475241 chr424080699 24080749 chr4 24253307 24253357 chr4 24259449 24259499 chr430017200 30017250 chr4 33948271 33948321 chr4 47685906 47685956 chr454802023 54802073 chr4 54807245 54807295 chr4 62639104 62639154 chr463224036 63224086 chr4 64854425 64854475 chr4 77836731 77836781 chr480589844 80589894 chr4 80933231 80933281 chr4 80939356 80939406 chr482800313 82800363 chr4 83669442 83669492 chr4 85016892 85016942 chr485230161 85230211 chr4 89315394 89315444 chr4 89532039 89532089 chr491350011 91350061 chr4 93405249 93405299 chr4 93410676 93410726 chr493650984 93651034 chr4 93818464 93818514 chr4 93824180 93824230 chr495546322 95546372 chr4 95678094 95678144 chr4 98519383 98519433 chr4104939518 104939568 chr11 66119805 66119855 chr4 110094867 110094917chr4 118424332 118424382 chr4 121379625 121379675 chr4 124392873124392923 chr4 127530500 127530550 chr4 130026112 130026162 chr4132147347 132147397 chr4 133498126 133498176 chr4 133504043 133504093chr4 134648395 134648445 chr4 136553172 136553222 chr4 139611876139611926 chr4 140426584 140426634 chr4 140656729 140656779 chr4147202267 147202317 chr4 147337526 147337576 chr4 154245912 154245962chr4 157608004 157608054 chr4 158099132 158099182 chr4 158104885158104935 chr4 159095522 159095572 chr4 160923873 160923923 chr4161424822 161424872 chr11 67192878 67192928 chr11 67193429 67193479 chr4164591811 164591861 chr4 164596397 164596447 chr4 168332962 168333012chr4 169057998 169058048 chr4 169635601 169635651 chr4 176105575176105625 chr4 176137194 176137244 chr4 177911249 177911299 chr4179124771 179124821 chr4 180787874 180787924 chr4 181021088 181021138chr4 183567576 183567626 chr4 184436135 184436185 chr4 186284161186284211 chr4 187660968 187661018 chr4 187859292 187859342 chr5 912356912406 chr5 5743960 5744010 chr5 7316324 7316374 chr5 7322196 7322246chr5 8467325 8467375 chr5 11643289 11643339 chr5 12542807 12542857 chr512547376 12547426 chr5 12721243 12721293 chr5 17119212 17119262 chr518580782 18580832 chr5 18585098 18585148 chr5 18589610 18589660 chr518720260 18720310 chr5 20382016 20382066 chr5 25491202 25491252 chr528975751 28975801 chr5 66709229 66709279 chr5 75743206 75743256 chr1170775900 70775950 chr5 79563182 79563232 chr5 79565564 79565614 chr1170943339 70943389 chr5 84084130 84084180 chr5 84244676 84244726 chr585027506 85027556 chr5 91124264 91124314 chr5 100568126 100568176 chr5103443513 103443563 chr5 106396051 106396101 chr5 107966923 107966973chr5 107979518 107979568 chr5 116027447 116027497 chr5 116234548116234598 chr5 116357235 116357285 chr5 116464191 116464241 chr5118364360 118364410 chr5 120109423 120109473 chr5 121886011 121886061chr5 121890851 121890901 chr5 122036268 122036318 chr5 126085557126085607 chr5 126251216 126251266 chr5 126257770 126257820 chr5128082581 128082631 chr5 130984055 130984105 chr5 133274584 133274634chr5 135149379 135149429 chr5 152863481 152863531 chr5 162741949162741999 chr5 166705983 166706033 chr5 170169927 170169977 chr5170416099 170416149 chr5 170777459 170777509 chr5 178730265 178730315chr5 179957273 179957323 chr6 5973003 5973053 chr11 77517974 77518024chr6 14411081 14411131 chr6 16367130 16367180 chr6 21470246 21470296chr6 21475468 21475518 chr6 26136987 26137037 chr6 28852995 28853045chr6 29057048 29057098 chr6 31843729 31843779 chr6 33895038 33895088chr6 38936351 38936401 chr6 39150625 39150675 chr6 43385251 43385301chr6 43406107 43406157 chr6 44838237 44838287 chr11 87471184 87471234chr6 63499024 63499074 chr6 66554993 66555043 chr6 68579259 68579309chr6 68594377 68594427 chr6 68594473 68594523 chr6 77266307 77266357chr6 78363667 78363717 chr6 88567143 88567193 chr6 91380742 91380792chr6 94536117 94536167 chr6 94541254 94541304 chr6 95259116 95259166chr6 95264979 95265029 chr6 110222353 110222403 chr11 94730706 94730756chr6 114794998 114795048 chr6 120764033 120764083 chr6 120769836120769886 chr6 123147437 123147487 chr6 123889807 123889857 chr6125199519 125199569 chr6 126009568 126009618 chr6 129048307 129048357chr6 131013775 131013825 chr6 131597688 131597738 chr6 131603056131603106 chr6 131640988 131641038 chr6 131810907 131810957 chr6137361814 137361864 chr6 137368815 137368865 chr6 142323680 142323730chr6 142950986 142951036 chr6 145230567 145230617 chr6 145410544145410594 chr6 154274812 154274862 chr6 157328521 157328571 chr6158030869 158030919 chr6 159210674 159210724 chr6 160564770 160564820chr6 165380628 165380678 chr6 165388524 165388574 chr11 107287554107287604 chr7 944810 944860 chr7 3857917 3857967 chr7 6745920 6745970chr7 9142563 9142613 chr7 19905094 19905144 chr7 20330595 20330645 chr724178459 24178509 chr7 24183918 24183968 chr7 25811936 25811986 chr726053306 26053356 chr7 32297009 32297059 chr7 32620141 32620191 chr732847359 32847409 chr7 34081861 34081911 chr7 42650927 42650977 chr742656407 42656457 chr7 42983531 42983581 chr7 50914770 50914820 chr764731010 64731060 chr7 67266410 67266460 chr7 67415464 67415514 chr770051472 70051522 chr7 75020685 75020735 chr7 76581874 76581924 chr776587031 76587081 chr7 82706787 82706837 chr7 99017947 99017997 chr7100136893 100136943 chr7 105768288 105768338 chr7 111051718 111051768chr7 112434981 112435031 chr7 112439865 112439915 chr7 119977531119977581 chr7 124459177 124459227 chr7 125104244 125104294 chr7128727639 128727689 chr7 137429128 137429178 chr7 138192994 138193044chr7 138560808 138560858 chr7 146698049 146698099 chr7 151059258151059308 chr10 17664563 17664613 chr8 1737344 1737394 chr11 121045678121045728 chr8 2156882 2156932 chr8 5281562 5281612 chr8 7238340 7238390chr11 121963934 121963984 chr8 8953796 8953846 chr8 9698422 9698472chr11 123206002 123206052 chr11 123273850 123273900 chr11 123279090123279140 chr8 27752817 27752867 chr8 30008238 30008288 chr8 3354197433542024 chr8 34775340 34775390 chr8 42997700 42997750 chr8 5883687158836921 chr8 60838329 60838379 chr8 68682129 68682179 chr8 7264270272642752 chr8 76179650 76179700 chr8 80353864 80353914 chr8 8288159782881647 chr8 84472759 84472809 chr8 89711218 89711268 chr8 9338480793384857 chr8 98143793 98143843 chr8 98169472 98169522 chr8 9817545398175503 chr8 98796663 98796713 chr8 99559150 99559200 chr8 100912384100912434 chr8 101464852 101464902 chr8 101877391 101877441 chr8104438989 104439039 chr8 109278996 109279046 chr8 114484292 114484342chr8 115210934 115210984 chr8 116783713 116783763 chr8 116788284116788334 chr8 122987406 122987456 chr8 124448649 124448699 chr8125497285 125497335 chr8 129586445 129586495 chr8 129883261 129883311chr8 132715467 132715517 chr8 136756471 136756521 chr11 129977196129977246 chr11 130161291 130161341 chr11 130166667 130166717 chr8144225651 144225701 chr8 144225523 144225573 chr8 144331505 144331555chr8 144362178 144362228 chr8 145922018 145922068 chr9 2266226 2266276chr9 3740055 3740105 chr9 3806137 3806187 chr9 3891195 3891245 chr93891098 3891148 chr9 6706607 6706657 chr9 6707491 6707541 chr9 1088015810880208 chr9 11092415 11092465 chr9 12431051 12431101 chr9 1294410912944159 chr9 21477966 21478016 chr9 21481096 21481146 chr9 2527832825278378 chr9 31316087 31316137 chr9 33367328 33367378 chr9 3347612433476174 chr9 35110654 35110704 chr9 41232777 41232827 chr9 6748207367482123 chr9 75026755 75026805 chr9 80778301 80778351 chr9 8096161980961669 chr9 83539045 83539095 chr9 84661072 84661122 chr9 8547986285479912 chr9 85480482 85480532 chr10 20663720 20663770 chr9 8640427386404323 chr9 88516171 88516221 chr9 88522155 88522205 chr9 9017592090175970 chr9 92648983 92649033 chr9 94929155 94929205 chr9 9535657995356629 chr9 96407215 96407265 chr9 96417384 96417434 chr9 9659611896596168 chr9 97811822 97811872 chr9 98288046 98288096 chr9 113611254113611304 chr9 113977435 113977485 chr9 113982690 113982740 chr9116623922 116623972 chr9 119935335 119935385 chr9 120674529 120674579chr9 124212720 124212770 chr9 124218772 124218822 chr9 129703599129703649 chr12 3496740 3496790 chr10 22044281 22044331 chr12 98782509878300 chr12 10376784 10376834 chr12 12102633 12102683 chr12 1342093113420981 chr12 17071615 17071665 chr12 17514646 17514696 chr12 1824011118240161 chr12 18248000 18248050 chr12 20866800 20866850 chr10 2374994223749992 chr12 29184416 29184466 chr12 29319814 29319864 chr12 3187676831876818 chr12 43130641 43130691 chr10 26061688 26061738 chr10 2606804626068096 chr12 53627988 53628038 chr12 65178259 65178309 chr12 6645237966452429 chr12 71383160 71383210 chr12 71389001 71389051 chr12 7149825271498302 chr12 71506337 71506387 chr12 78436041 78436091 chr12 7844185878441908 chr12 102118271 102118321 chr12 107340789 107340839 chr12112913349 112913399 chr12 119337103 119337153 chr12 119345589 119345639chr12 119345823 119345873 chr12 126857744 126857794 chr12 130271912130271962 chr12 130574418 130574468 chr12 131705337 131705387 chr12131772354 131772404 chr12 131772964 131773014 chr13 23392028 23392078chr13 24885234 24885284 chr13 28973530 28973580 chr13 31232180 31232230chr13 33171348 33171398 chr13 33175567 33175617 chr13 41431715 41431765chr10 38084503 38084553 chr13 43171764 43171814 chr13 44666918 44666968chr13 46428340 46428390 chr13 47835474 47835524 chr13 49541967 49542017chr13 49547155 49547205 chr13 52505058 52505108 chr13 53956347 53956397chr13 54027032 54027082 chr13 54033072 54033122 chr13 54418429 54418479chr13 59577703 59577753 chr13 61585295 61585345 chr13 64598227 64598277chr13 64604546 64604596 chr13 67569632 67569682 chr13 76305325 76305375chr13 77646177 77646227 chr13 77652117 77652167 chr13 78562086 78562136chr13 80244312 80244362 chr13 82285955 82286005 chr13 83789886 83789936chr13 84115741 84115791 chr13 89190230 89190280 chr13 94351831 94351881chr13 96412027 96412077 chr13 107615852 107615902 chr13 107621559107621609 chr10 44535441 44535491 chr10 44537559 44537609 chr14 1927332819273378 chr14 22399362 22399412 chr14 22399170 22399220 chr14 2389003823890088 chr14 24989571 24989621 chr14 29710654 29710704 chr10 7864678696 chr14 36655915 36655965 chr10 48887289 48887339 chr14 4447158244471632 chr14 44477325 44477375 chr14 45568223 45568273 chr14 4672749546727545 chr14 48503541 48503591 chr14 49425524 49425574 chr14 5959549459595544 chr14 68758260 68758310 chr14 69581419 69581469 chr14 7404240074042450 chr10 53143958 53144008 chr14 81682161 81682211 chr14 8418874384188793 chr14 84194958 84195008 chr14 87896544 87896594 chr10 5459685054596900 chr10 54609192 54609242 chr10 55276843 55276893 chr14 9202145192021501 chr14 97449301 97449351 chr14 99767723 99767773 chr10 5919861859198668 chr10 59965264 59965314 chr10 59971866 59971916 chr15 2578113825781188 chr15 33263303 33263353 chr15 44688314 44688364 chr10 6453643464536484 chr15 51435015 51435065 chr15 51440809 51440859 chr15 5372604053726090 chr15 60305177 60305227 chr15 61307738 61307788 chr15 6352784363527893 chr15 63529569 63529619 chr15 72257326 72257376 chr15 7307234673072396 chr15 77886395 77886445 chr15 77886175 77886225 chr15 8610393986103989 chr15 86110020 86110070 chr15 86820205 86820255 chr15 8841134088411390 chr15 91052683 91052733 chr15 95144767 95144817 chr15 9515064795150697 chr15 98715686 98715736 chr15 99348380 99348430 chr16 6508465134 chr10 70158564 70158614 chr16 3214500 3214550 chr16 33046553304705 chr16 7864320 7864370 chr16 8894168 8894218 chr16 89059618906011 chr16 9731512 9731562 chr16 10422510 10422560 chr16 1341281213412862 chr16 13418459 13418509 chr16 18968603 18968653 chr16 1988630119886351 chr16 24469265 24469315 chr16 25544758 25544808 chr16 4698207146982121 chr10 73011958 73012008 chr16 56483472 56483522 chr16 5933228559332335 chr16 59893668 59893718 chr16 65044363 65044413 chr16 6508814565088195 chr16 71518632 71518682 chr16 82924124 82924174 chr16 8419444184194491 chr16 86093144 86093194 chr16 86096590 86096640 chr16 8655683886556888 chr16 89060522 89060572 chr16 89234080 89234130 chr17 53436925343742 chr17 6841059 6841109 chr17 7246205 7246255 chr10 7792299277923042 chr17 8456399 8456449 chr17 12080812 12080862 chr17 1730453417304584 chr17 19958586 19958636 chr17 32656351 32656401 Table 15BP.Repeat Category LTR7B chr17 53570257 53570307 chr17 65970811 65970861chr17 79074224 79074274 chr10 92769228 92769278 chr10 98986394 98986444chr19 320411 320461 chr19 2852265 2852315 chr19 5797840 5797890 chr195808683 5808733 chr19 41442157 41442207 chr19 42617725 42617775 chr10110023910 110023960 chr19 52244705 52244755 chr19 59748223 59748273chr19 60332108 60332158 chr1 13249804 13249854 chr1 25842410 25842460chr1 40838589 40838639 chr1 41704211 41704261 chr1 57579138 57579188chr1 58539268 58539318 chr1 64973506 64973556 chr1 64981409 64981459chr1 91510808 91510858 chr1 116751098 116751148 chr1 200259625 200259675chr1 207440302 207440352 chr1 234142406 234142456 chr1 234693440234693490 chr1 235480380 235480430 chr1 243528719 243528769 chr1243796303 243796353 chr1 244189592 244189642 chr20 4635833 4635883 chr2018492481 18492531 chr20 18498196 18498246 chr20 19727641 19727691 chr2055854040 55854090 chr22 37701491 37701541 chr22 41192174 41192224 chr2243803544 43803594 chrX 69351664 69351714 chrX 72238335 72238385 chrX96316297 96316347 chrX 107836776 107836826 chrX 111187735 111187785 chrX112054385 112054435 chrX 132785064 132785114 chrX 140212967 140213017chr11 14510814 14510864 chr2 45241595 45241645 chr2 99848100 99848150chr2 101416235 101416285 chr2 138790890 138790940 chr11 3776054137760591 chr2 184128127 184128177 chr11 39720435 39720485 chr2 223915799223915849 chr3 11287847 11287897 chr3 27616047 27616097 chr3 4196690541966955 chr3 99284120 99284170 chr3 120165128 120165178 chr3 129874226129874276 chr3 129881265 129881315 chr3 154867467 154867517 chr3183781376 183781426 chr4 30017200 30017250 chr4 54802023 54802073 chr454807245 54807295 chr4 63224036 63224086 chr4 77836731 77836781 chr480589844 80589894 chr4 83669442 83669492 chr4 85016892 85016942 chr4164591811 164591861 chr4 164596397 164596447 chr5 11643289 11643339 chr528975751 28975801 chr5 130984055 130984105 chr5 170416099 170416149 chr5170777459 170777509 chr5 178730265 178730315 chr6 29057048 29057098 chr631843729 31843779 chr6 33895038 33895088 chr6 43385251 43385301 chr1187471184 87471234 chr6 66554993 66555043 chr6 68594377 68594427 chr668594473 68594523 chr6 78363667 78363717 chr6 157328521 157328571 chr6159210674 159210724 chr11 107287554 107287604 chr7 944810 944860 chr726053306 26053356 chr7 70051472 70051522 chr7 105768288 105768338 chr7137429128 137429178 chr8 89711218 89711268 chr8 98796663 98796713 chr8116788284 116788334 chr8 122987406 122987456 chr9 3891195 3891245 chr93891098 3891148 chr9 11092415 11092465 chr9 33367328 33367378 chr935110654 35110704 chr9 86404273 86404323 chr9 90175920 90175970 chr992648983 92649033 chr12 17071615 17071665 chr10 23749942 23749992 chr1271389001 71389051 chr12 107340789 107340839 chr12 112913349 112913399chr12 131772354 131772404 chr12 131772964 131773014 chr13 2339202823392078 chr13 28973530 28973580 chr13 41431715 41431765 chr13 8228595582286005 chr13 96412027 96412077 chr14 19273328 19273378 chr14 7404240074042450 chr15 88411340 88411390 chr16 8894168 8894218 chr16 89059618906011 chr16 18968603 18968653 chr16 56483472 56483522 chr16 8419444184194491 chr17 5343692 5343742 chr17 6841059 6841109 chr17 72462057246255 chr17 8456399 8456449 chr17 19958586 19958636 Table 15BQ. RepeatCategory LTR7Y chr10 91725026 91725076 chr18 69141295 69141345 chr195808683 5808733 chr19 10005395 10005445 chr19 15801176 15801226 chr1915801049 15801099 chr19 21841739 21841789 chr10 110987213 110987263 chr112700193 12700243 chr1 20408931 20408981 chr1 81961181 81961231 chr183947197 83947247 chr1 94595290 94595340 chr1 108362484 108362534 chr1184979006 184979056 chr1 243795101 243795151 chr20 12321818 12321868chr20 36304577 36304627 chr20 39407139 39407189 chr20 39413065 39413115chr22 19187029 19187079 chr22 19187947 19187997 chr22 26462786 26462836chr22 37678648 37678698 chr22 37769940 37769990 chrX 3066239 3066289chrX 115172922 115172972 chrX 117205817 117205867 chr2 44226357 44226407chr11 20553729 20553779 chr2 58315050 58315100 chr2 58320785 58320835chr2 193197623 193197673 chr11 42111217 42111267 chr3 48726495 48726545chr3 125797321 125797371 chr11 61587529 61587579 chr3 157083847157083897 chr3 157083481 157083531 chr3 188224308 188224358 chr493405249 93405299 chr4 93410676 93410726 chr4 95678094 95678144 chr4104939518 104939568 chr4 127530500 127530550 chr4 139611876 139611926chr4 154245912 154245962 chr4 169057998 169058048 chr4 176105575176105625 chr4 184436135 184436185 chr5 8467325 8467375 chr5 1254280712542857 chr5 12547376 12547426 chr5 79563182 79563232 chr5 100568126100568176 chr5 121890851 121890901 chr5 179957273 179957323 chr1177517974 77518024 chr6 39150625 39150675 chr11 94730706 94730756 chr6120764033 120764083 chr6 125199519 125199569 chr6 131810907 131810957chr6 145230567 145230617 chr6 154274812 154274862 chr7 25811936 25811986chr7 34081861 34081911 chr7 112434981 112435031 chr7 112439865 112439915chr8 80353864 80353914 chr8 98143793 98143843 chr8 99559150 99559200chr8 116783713 116783763 chr8 136756471 136756521 chr11 129977196129977246 chr9 21481096 21481146 chr9 75026755 75026805 chr9 8077830180778351 chr9 84661072 84661122 chr12 17514646 17514696 chr12 126857744126857794 chr13 33171348 33171398 chr13 33175567 33175617 chr13 8919023089190280 chr13 107615852 107615902 chr13 107621559 107621609 chr1422399362 22399412 chr14 22399170 22399220 chr14 29710654 29710704 chr1481682161 81682211 chr15 25781138 25781188 chr15 33263303 33263353 chr1551435015 51435065 chr15 51440809 51440859 chr15 53726040 53726090 chr1591052683 91052733 chr16 86093144 86093194 chr16 86096590 86096640 chr175343692 5343742 chr10 77922992 77923042 chr17 12080812 12080862 chr1732656351 32656401 Table 15BR. Repeat Category LTR8 chr17 3847908638479136 chr17 43389204 43389254 chr17 47630768 47630818 chr10 8409971884099768 chr17 66301781 66301831 chr17 67940971 67941021 chr17 7146637371466423 chr17 74576553 74576603 chr17 76967249 76967299 chr17 7883834878838398 chr17 80300784 80300834 chr17 81389895 81389945 chr10 9382635793826407 chr10 4863106 4863156 chr18 53654288 53654338 chr18 5999466059994710 chr18 66200360 66200410 chr18 73429174 73429224 chr19 211332211382 chr19 2109709 2109759 chr19 2113827 2113877 chr19 2417602 2417652chr19 2419597 2419647 chr19 2904015 2904065 chr19 7052532 7052582 chr1912008845 12008895 chr19 12036997 12037047 chr19 12038223 12038273 chr1912267023 12267073 chr19 12268678 12268728 chr19 12855135 12855185 chr1913636202 13636252 chr19 14767399 14767449 chr19 17387418 17387468 chr1918293716 18293766 chr19 44047905 44047955 chr19 44048422 44048472 chr1944048600 44048650 chr19 44049077 44049127 chr19 45375634 45375684 chr10105608127 105608177 chr19 46997083 46997133 chr19 49505457 49505507chr19 50773479 50773529 chr19 50777525 50777575 chr19 50778188 50778238chr19 53631010 53631060 chr19 57098875 57098925 chr19 60208510 60208560chr19 63022959 63023009 chr19 63119545 63119595 chr1 9281222 9281272chr1 10819727 10819777 chr1 20317475 20317525 chr1 24910672 24910722chr1 24911038 24911088 chr1 31147815 31147865 chr1 32604453 32604503chr10 6440911 6440961 chr1 45193098 45193148 chr1 62014127 62014177 chr165134045 65134095 chr1 75673274 75673324 chr1 75673868 75673918 chr175674105 75674155 chr1 75674428 75674478 chr1 89000532 89000582 chr189000705 89000755 chr1 89441007 89441057 chr1 91159585 91159635 chr199696143 99696193 chr1 110109997 110110047 chr1 158155769 158155819 chr1179647472 179647522 chr1 198424803 198424853 chr1 220253922 220253972chr1 220528469 220528519 chr1 226330435 226330485 chr1 231628722231628772 chr1 238339949 238339999 chr1 241846302 241846352 chr1241850323 241850373 chr1 243193452 243193502 chr1 244214412 244214462chr1 244485834 244485884 chr20 753042 753092 chr20 5595008 5595058 chr205599935 5599985 chr20 13995802 13995852 chr20 16599338 16599388 chr10133236728 133236778 chr10 133469033 133469083 chr10 133468972 133469022chr20 36878178 36878228 chr20 42971427 42971477 chr20 43841592 43841642chr20 43843584 43843634 chr20 44759601 44759651 chr20 44759384 44759434chr20 47775676 47775726 chr20 52445703 52445753 chr20 53157668 53157718chr20 57196000 57196050 chr10 134630449 134630499 chr10 134632230134632280 chr21 19277888 19277938 chr11 306405 306455 chr21 2493015124930201 chr21 36391827 36391877 chr21 39828507 39828557 chr21 3987251639872566 chr11 738590 738640 chr21 43242867 43242917 chr21 4324298043243030 chr21 43244130 43244180 chr21 43275985 43276035 chr22 1469335614693406 chr22 23003129 23003179 chr22 28302489 28302539 chr22 2830342428303474 chr22 34392887 34392937 chr22 34393443 34393493 chr22 3439509934395149 chr22 39346774 39346824 chr22 41298475 41298525 chr22 4608075846080808 chr22 46535717 46535767 chr22 48127187 48127237 chr22 4921388049213930 chrX 2315697 2315747 chrX 2317816 2317866 chrX 2483102 2483152chrX 2686180 2686230 chrX 3918521 3918571 chrX 4779081 4779131 chrX12811361 12811411 chrX 16147428 16147478 chrX 30162570 30162620 chrX39697101 39697151 chrX 43388947 43388997 chrX 43525237 43525287 chrX45164723 45164773 chrX 45437701 45437751 chrX 46283909 46283959 chr117956114 7956164 chr11 7955709 7955759 chrX 63250412 63250462 chrX69423204 69423254 chrX 96391570 96391620 chrX 99098551 99098601 chrX99100106 99100156 chrX 109566684 109566734 chrX 119232011 119232061 chrX122066625 122066675 chr11 14162704 14162754 chrY 13568592 13568642 chrY13804461 13804511 chrY 17208727 17208777 chr2 11313885 11313935 chr216116695 16116745 chr2 24585626 24585676 chr2 25379603 25379653 chr1118644797 18644847 chr2 33805759 33805809 chr2 36847108 36847158 chr243092909 43092959 chr2 45792265 45792315 chr2 47529103 47529153 chr247899899 47899949 chr2 50079611 50079661 chr2 81186594 81186644 chr296585806 96585856 chr2 96591337 96591387 chr2 106397094 106397144 chr2108481066 108481116 chr2 108633115 108633165 chr2 109334729 109334779chr2 122555188 122555238 chr2 128928168 128928218 chr2 134840943134840993 chr2 151936778 151936828 chr2 157492741 157492791 chr2164144919 164144969 chr2 172971467 172971517 chr2 174374565 174374615chr2 174376460 174376510 chr2 175751791 175751841 chr2 212657826212657876 chr2 228820072 228820122 chr2 238661398 238661448 chr1146553554 46553604 chr3 5127176 5127226 chr3 5276446 5276496 chr3 77486887748738 chr3 9658743 9658793 chr3 9860757 9860807 chr3 15413956 15414006chr3 27621952 27622002 chr3 31997632 31997682 chr3 36677325 36677375chr3 38347087 38347137 chr3 40554525 40554575 chr3 42798928 42798978chr3 47481513 47481563 chr3 48242223 48242273 chr3 67754767 67754817chr11 59088252 59088302 chr3 101622392 101622442 chr3 123349358123349408 chr3 133316318 133316368 chr3 143296932 143296982 chr3156992685 156992735 chr11 61891217 61891267 chr3 173934752 173934802chr3 195615410 195615460 chr3 197176409 197176459 chr3 197200014197200064 chr3 197220210 197220260 chr3 197356836 197356886 chr3197396619 197396669 chr3 197497119 197497169 chr3 197499422 197499472chr3 197897775 197897825 chr4 8686281 8686331 chr4 10304685 10304735chr4 17325347 17325397 chr4 24615859 24615909 chr4 25370726 25370776chr4 29142097 29142147 chr4 32548735 32548785 chr4 57541876 57541926chr4 63843319 63843369 chr4 84107540 84107590 chr4 86169587 86169637chr4 88801606 88801656 chr4 90664378 90664428 chr4 90664171 90664221chr4 97764135 97764185 chr4 100403699 100403749 chr4 101166999 101167049chr4 104083333 104083383 chr4 108857512 108857562 chr4 126940607126940657 chr4 131310251 131310301 chr4 165740357 165740407 chr4176961241 176961291 chr4 186226357 186226407 chr11 68206349 68206399chr4 187708047 187708097 chr4 191457244 191457294 chr5 8049675 8049725chr5 17468688 17468738 chr5 18599684 18599734 chr5 19384198 19384248chr5 27141582 27141632 chr5 36637185 36637235 chr5 43118264 43118314chr5 53324958 53325008 chr5 53817100 53817150 chr5 56513013 56513063chr5 77131402 77131452 chr5 79514033 79514083 chr5 81327129 81327179chr5 84847406 84847456 chr5 103475119 103475169 chr5 108836390 108836440chr10 14422378 14422428 chr5 127168179 127168229 chr5 150709491150709541 chr5 150709816 150709866 chr5 157328767 157328817 chr5172216424 172216474 chr5 172449811 172449861 chr5 175020076 175020126chr5 180803497 180803547 chr6 804608 804658 chr11 77075747 77075797 chr63894186 3894236 chr6 10844331 10844381 chr6 15311067 15311117 chr615312756 15312806 chr6 15802362 15802412 chr6 16325023 16325073 chr621653634 21653684 chr6 27722850 27722900 chr6 27956148 27956198 chr629045975 29046025 chr6 30396548 30396598 chr6 31563106 31563156 chr656628499 56628549 chr6 56941147 56941197 chr6 71630463 71630513 chr676590178 76590228 chr6 107344884 107344934 chr6 127675438 127675488 chr6132163918 132163968 chr11 97474790 97474840 chr6 142271154 142271204chr6 147750043 147750093 chr6 151565426 151565476 chr6 158175191158175241 chr6 160226996 160227046 chr11 101881604 101881654 chr11101974556 101974606 chr6 162861843 162861893 chr7 1185198 1185248 chr72993174 2993224 chr7 5008567 5008617 chr7 6353292 6353342 chr7 63544506354500 chr7 26120268 26120318 chr7 29105569 29105619 chr7 3744395137444001 chr7 39931293 39931343 chr7 44768957 44769007 chr7 4616898746169037 chr7 55193681 55193731 chr7 67551002 67551052 chr7 6997951369979563 chr7 70312790 70312840 chr7 71440322 71440372 chr7 7221722372217273 chr7 73277695 73277745 chr7 73279639 73279689 chr7 7504682875046878 chr7 75427206 75427256 chr7 75428470 75428520 chr7 7777781577777865 chr7 78857920 78857970 chr7 100142002 100142052 chr7 100476168100476218 chr10 17435115 17435165 chr11 118264175 118264225 chr7129418230 129418280 chr7 137307934 137307984 chr7 137358824 137358874chr7 137412552 137412602 chr7 139593021 139593071 chr7 141101242141101292 chr7 147241919 147241969 chr7 154218861 154218911 chr7156303862 156303912 chr10 17966490 17966540 chr8 1736253 1736303 chr81736186 1736236 chr8 1737344 1737394 chr10 18213400 18213450 chr82987047 2987097 chr8 3970418 3970468 chr8 6612418 6612468 chr8 2654862026548670 chr8 30163171 30163221 chr8 41686359 41686409 chr8 4894964648949696 chr8 81352205 81352255 chr8 90881101 90881151 chr8 9158680391586853 chr8 91586500 91586550 chr8 98740673 98740723 chr8 129070264129070314 chr8 144233820 144233870 chr9 15126155 15126205 chr9 2410777224107822 chr9 37393585 37393635 chr9 42396698 42396748 chr9 6260912762609177 chr9 82462270 82462320 chr9 86426032 86426082 chr9 8644850386448553 chr9 86583986 86584036 chr9 108412234 108412284 chr9 109960080109960130 chr9 110993525 110993575 chr9 111048161 111048211 chr9115266322 115266372 chr9 133800282 133800332 chr10 21686937 21686987chr9 135692103 135692153 chr9 135692276 135692326 chr12 8864704 8864754chr12 8875406 8875456 chr12 12919904 12919954 chr12 23408640 23408690chr12 38856834 38856884 chr12 45981834 45981884 chr12 46642368 46642418chr12 51791449 51791499 chr12 66047339 66047389 chr12 74427811 74427861chr12 89113498 89113548 chr12 92927593 92927643 chr10 30571889 30571939chr12 116967454 116967504 chr12 118280951 118281001 chr12 121614687121614737 chr12 121632499 121632549 chr12 121837260 121837310 chr12122907697 122907747 chr12 123757609 123757659 chr12 126582794 126582844chr12 126784590 126784640 chr12 131260958 131261008 chr13 2125539221255442 chr13 22900809 22900859 chr13 28345729 28345779 chr13 4125196041252010 chr13 43100113 43100163 chr13 44378379 44378429 chr13 4797498647975036 chr13 58956760 58956810 chr13 67305995 67306045 chr13 6797724567977295 chr13 75385665 75385715 chr13 82285955 82286005 chr13 8395865183958701 chr13 84049778 84049828 chr13 84732843 84732893 chr13 9683604996836099 chr13 112528322 112528372 chr14 19132231 19132281 chr1419656490 19656540 chr14 21187554 21187604 chr14 25211335 25211385 chr1432817041 32817091 chr14 48339272 48339322 chr14 48339865 48339915 chr1450578785 50578835 chr14 52930468 52930518 chr14 62105065 62105115 chr1462821335 62821385 chr14 75548271 75548321 chr14 80073311 80073361 chr1054128381 54128431 chr14 90055443 90055493 chr14 91035870 91035920 chr1523816087 23816137 chr15 25064407 25064457 chr15 29139022 29139072 chr1533069427 33069477 chr15 39159919 39159969 chr15 39602416 39602466 chr1540851693 40851743 chr15 41731703 41731753 chr15 48797600 48797650 chr1553435645 53435695 chr15 61389910 61389960 chr15 61391052 61391102 chr1565910930 65910980 chr15 66031287 66031337 chr15 73155124 73155174 chr1587263415 87263465 chr15 99439815 99439865 chr16 1934427 1934477 chr161934980 1935030 chr10 70409128 70409178 chr16 2847001 2847051 chr168162325 8162375 chr16 12870144 12870194 chr10 71493102 71493152 chr1617722017 17722067 chr16 20540738 20540788 chr16 25551808 25551858 chr1626996996 26997046 chr16 27060510 27060560 chr16 31316426 31316476 chr1646465470 46465520 chr16 64527680 64527730 chr16 69604050 69604100 chr1678878402 78878452 chr16 80909534 80909584 chr16 81703347 81703397 chr1685787634 85787684 chr10 407098 407148 chr17 259399 259449 chr17 316603316653 chr17 5030486 5030536 chr17 7246205 7246255 chr17 7642629 7642679chr17 8087569 8087619 chr17 9437562 9437612 chr17 9520537 9520587 chr1716348340 16348390 chr10 3737554 3737604 chr17 30633815 30633865 chr1731909319 31909369 chr17 37586734 37586784 Table 15BS. Repeat CategoryLTR8A chr17 47630768 47630818 chr10 84099718 84099768 chr17 6794097167941021 chr17 74576553 74576603 chr17 78838348 78838398 chr17 8138989581389945 chr19 2417602 2417652 chr19 2419597 2419647 chr19 29040152904065 chr19 12036997 12037047 chr19 12038223 12038273 chr19 1226702312267073 chr19 12268678 12268728 chr19 12855135 12855185 chr19 1738741817387468 chr19 45375634 45375684 chr19 46997083 46997133 chr1 2491067224910722 chr1 24911038 24911088 chr1 110109997 110110047 chr1 158155769158155819 chr1 198424803 198424853 chr1 220253922 220253972 chr1220528469 220528519 chr1 226330435 226330485 chr1 238339949 238339999chr1 243193452 243193502 chr1 244485834 244485884 chr20 753042 753092chr20 5595008 5595058 chr20 13995802 13995852 chr20 36878178 36878228chr20 57196000 57196050 chr21 19277888 19277938 chr11 306405 306455chr11 738590 738640 chr21 43244130 43244180 chr22 39346774 39346824chr22 48127187 48127237 chrX 3918521 3918571 chrX 12811361 12811411 chrX45437701 45437751 chr11 7956114 7956164 chr11 7955709 7955759 chr224585626 24585676 chr2 81186594 81186644 chr2 106397094 106397144 chr2128928168 128928218 chr2 151936778 151936828 chr2 164144919 164144969chr2 238661398 238661448 chr11 46553554 46553604 chr3 5276446 5276496chr3 7748688 7748738 chr3 9860757 9860807 chr3 15413956 15414006 chr327621952 27622002 chr3 31997632 31997682 chr3 40554525 40554575 chr347481513 47481563 chr3 48242223 48242273 chr11 61891217 61891267 chr3197200014 197200064 chr3 197220210 197220260 chr3 197499422 197499472chr4 8686281 8686331 chr4 10304685 10304735 chr4 29142097 29142147 chr457541876 57541926 chr4 84107540 84107590 chr4 90664378 90664428 chr490664171 90664221 chr4 101166999 101167049 chr4 165740357 165740407 chr4176961241 176961291 chr11 68206349 68206399 chr4 191457244 191457294chr5 27141582 27141632 chr5 43118264 43118314 chr5 53324958 53325008chr5 53817100 53817150 chr5 56513013 56513063 chr5 157328767 157328817chr5 172216424 172216474 chr5 175020076 175020126 chr6 804608 804658chr6 3894186 3894236 chr6 16325023 16325073 chr6 21653634 21653684 chr629045975 29046025 chr6 31563106 31563156 chr6 56628499 56628549 chr671630463 71630513 chr6 107344884 107344934 chr6 127675438 127675488 chr6142271154 142271204 chr6 147750043 147750093 chr6 151565426 151565476chr11 101974556 101974606 chr7 1185198 1185248 chr7 2993174 2993224 chr76354450 6354500 chr7 29105569 29105619 chr7 55193681 55193731 chr769979513 69979563 chr7 71440322 71440372 chr7 73277695 73277745 chr773279639 73279689 chr7 75046828 75046878 chr7 75427206 75427256 chr775428470 75428520 chr7 100476168 100476218 chr7 141101242 141101292 chr7147241919 147241969 chr7 154218861 154218911 chr7 156303862 156303912chr8 1736253 1736303 chr8 1736186 1736236 chr8 1737344 1737394 chr826548620 26548670 chr8 41686359 41686409 chr8 81352205 81352255 chr890881101 90881151 chr8 91586803 91586853 chr8 91586500 91586550 chr898740673 98740723 chr8 129070264 129070314 chr9 135692103 135692153 chr9135692276 135692326 chr12 23408640 23408690 chr12 38856834 38856884chr12 89113498 89113548 chr12 126784590 126784640 chr13 2290080922900859 chr13 41251960 41252010 chr13 47974986 47975036 chr13 8228595582286005 chr14 25211335 25211385 chr14 50578785 50578835 chr14 7554827175548321 chr14 80073311 80073361 chr15 40851693 40851743 chr15 6603128766031337 chr15 87263415 87263465 chr16 17722017 17722067 chr16 2054073820540788 chr16 25551808 25551858 chr16 27060510 27060560 chr16 6960405069604100 chr16 78878402 78878452 chr16 81703347 81703397 chr17 95205379520587 chr17 30633815 30633865 chr17 31909319 31909369 Table 15BT.Repeat Category LTR9 chr17 52185310 52185360 chr17 65868183 65868233chr17 69674264 69674314 chr10 90983283 90983333 chr10 91779633 91779683chr10 92237746 92237796 chr18 3320719 3320769 chr18 3320816 3320866chr10 93837233 93837283 chr18 6918643 6918693 chr18 8926006 8926056chr18 13660988 13661038 chr18 16910157 16910207 chr18 27576432 27576482chr18 44030534 44030584 chr18 45232942 45232992 chr18 53647462 53647512chr18 67104173 67104223 chr18 71905396 71905446 chr19 6553460 6553510chr19 6555861 6555911 chr19 6836367 6836417 chr19 6835869 6835919 chr196881254 6881304 chr19 9204350 9204400 chr19 13510005 13510055 chr1914627649 14627699 chr19 14647844 14647894 chr19 14648466 14648516 chr1914648655 14648705 chr19 14730921 14730971 chr19 14775974 14776024 chr1916109033 16109083 chr10 103610338 103610388 chr19 18936286 18936336chr19 18937390 18937440 chr19 21674557 21674607 chr19 24128575 24128625chr19 37445850 37445900 chr19 39085948 39085998 chr19 49307995 49308045chr19 49308182 49308232 chr19 49308398 49308448 chr19 54923054 54923104chr19 55787269 55787319 chr19 56442846 56442896 chr19 61082548 61082598chr19 61601326 61601376 chr1 7846387 7846437 chr10 116714434 116714484chr1 9281222 9281272 chr1 12376074 12376124 chr1 14093112 14093162 chr115198503 15198553 chr1 27132689 27132739 chr1 39857947 39857997 chr148043929 48043979 chr1 51846084 51846134 chr10 123410780 123410830 chr155292584 55292634 chr1 75611654 75611704 chr1 112693661 112693711 chr1113866366 113866416 chr1 158008800 158008850 chr1 158162413 158162463chr1 185772310 185772360 chr1 193394775 193394825 chr1 204998449204998499 chr1 205083107 205083157 chr1 205082948 205082998 chr1207466474 207466524 chr1 216500736 216500786 chr1 216500430 216500480chr1 218944298 218944348 chr1 218944174 218944224 chr1 220264991220265041 chr1 225819978 225820028 chr1 226128214 226128264 chr1227794895 227794945 chr1 229309751 229309801 chr1 232632953 232633003chr1 233492800 233492850 chr1 233721937 233721987 chr10 131792040131792090 chr1 242390069 242390119 chr1 242390126 242390176 chr1243201130 243201180 chr20 4181311 4181361 chr20 11387711 11387761 chr2011448629 11448679 chr20 12676491 12676541 chr20 12775675 12775725 chr2034665989 34666039 chr20 40987783 40987833 chr20 42609553 42609603 chr2042610221 42610271 chr20 46837506 46837556 chr20 47118528 47118578 chr2051639041 51639091 chr20 52971069 52971119 chr20 52971713 52971763 chr2117587571 17587621 chr21 25136360 25136410 chr21 31486787 31486837 chr2131869165 31869215 chr21 31934483 31934533 chr21 33654906 33654956 chr2134993531 34993581 chr21 38413983 38414033 chr21 38413841 38413891 chr2139198026 39198076 chr21 44476192 44476242 chr22 42670580 42670630 chrX2559458 2559508 chrX 3105577 3105627 chrX 6201892 6201942 chrX 1258137112581421 chrX 13739636 13739686 chrX 15127494 15127544 chrX 2603366526033715 chrX 30393950 30394000 chr11 6308826 6308876 chrX 4516472345164773 chrX 87783484 87783534 chrX 87789407 87789457 chrX 9246547092465520 chrX 101884039 101884089 chr11 9758708 9758758 chrX 107984908107984958 chrX 111624328 111624378 chrX 121651307 121651357 chrX138718853 138718903 chrY 2532649 2532699 chrY 2981340 2981390 chrY4174253 4174303 chrY 20100026 20100076 chr2 24975120 24975170 chr230388405 30388455 chr2 38309454 38309504 chr2 53848462 53848512 chr264282881 64282931 chr2 65933219 65933269 chr2 70822185 70822235 chr274393201 74393251 chr2 78359108 78359158 chr2 81600536 81600586 chr289153971 89154021 chr2 102989106 102989156 chr2 111541407 111541457 chr2119414340 119414390 chr2 128676950 128677000 chr2 143675794 143675844chr2 143717275 143717325 chr2 155362324 155362374 chr2 166052823166052873 chr2 191186576 191186626 chr2 192545092 192545142 chr2192571583 192571633 chr2 203746179 203746229 chr2 207007232 207007282chr11 43940243 43940293 chr2 224791065 224791115 chr2 231229906231229956 chr3 2997588 2997638 chr3 3259320 3259370 chr10 1240824612408296 chr3 25960832 25960882 chr3 43419361 43419411 chr3 4568638745686437 chr3 48242223 48242273 chr3 52160154 52160204 chr3 7744309477443144 chr11 58438926 58438976 chr3 80372275 80372325 chr11 5850219258502242 chr11 58597031 58597081 chr11 58640822 58640872 chr3 9769752397697573 chr3 99364901 99364951 chr3 121304032 121304082 chr3 130487602130487652 chr3 136630758 136630808 chr3 141755168 141755218 chr3155101775 155101825 chr3 173715449 173715499 chr3 181920034 181920084chr4 8245500 8245550 chr4 13456119 13456169 chr4 40159666 40159716 chr440169083 40169133 chr4 56118613 56118663 chr4 74230105 74230155 chr484513306 84513356 chr4 84574672 84574722 chr4 84575486 84575536 chr4110767182 110767232 chr4 111014484 111014534 chr4 129111573 129111623chr4 130548050 130548100 chr4 134756686 134756736 chr4 146033725146033775 chr4 157736172 157736222 chr4 162750729 162750779 chr4169315695 169315745 chr4 174159601 174159651 chr4 177519833 177519883chr4 178242771 178242821 chr4 185868320 185868370 chr4 185868686185868736 chr4 185868922 185868972 chr4 186552758 186552808 chr4186552855 186552905 chr4 190618920 190618970 chr5 12714391 12714441 chr512715678 12715728 chr5 13888563 13888613 chr5 14950750 14950800 chr523271333 23271383 chr5 31633753 31633803 chr5 32958586 32958636 chr538706031 38706081 chr5 54518737 54518787 chr5 72517017 72517067 chr576268908 76268958 chr5 93774659 93774709 chr5 109800039 109800089 chr1171858634 71858684 chr5 126153252 126153302 chr5 131654018 131654068 chr5133753936 133753986 chr5 140863161 140863211 chr5 151117545 151117595chr5 151526252 151526302 chr11 74320868 74320918 chr5 157127398157127448 chr5 157127970 157128020 chr5 157374093 157374143 chr5159150381 159150431 chr5 173372337 173372387 chr11 77189673 77189723chr11 77189811 77189861 chr6 10784560 10784610 chr6 15142299 15142349chr6 18615023 18615073 chr6 21762273 21762323 chr6 30949092 30949142chr6 30949432 30949482 chr6 30949826 30949876 chr6 37439162 37439212chr6 54305013 54305063 chr6 64100292 64100342 chr6 70327681 70327731chr6 118946792 118946842 chr6 119868884 119868934 chr6 123152233123152283 chr11 97382143 97382193 chr6 138257269 138257319 chr6141450396 141450446 chr6 147750043 147750093 chr6 151869920 151869970chr6 156712221 156712271 chr6 159238556 159238606 chr10 1593608715936137 chr7 3824292 3824342 chr7 4315517 4315567 chr7 6994552 6994602chr7 7500601 7500651 chr7 7500936 7500986 chr7 8973781 8973831 chr710692589 10692639 chr7 21880835 21880885 chr7 32689416 32689466 chr734906222 34906272 chr7 43450030 43450080 chr7 56394087 56394137 chr763604713 63604763 chr7 66269495 66269545 chr7 66755146 66755196 chr766937518 66937568 chr7 67188081 67188131 chr7 67192109 67192159 chr769770542 69770592 chr7 69963982 69964032 chr7 70871785 70871835 chr772989261 72989311 chr7 78210486 78210536 chr7 101269111 101269161 chr7105745327 105745377 chr7 120631326 120631376 chr7 122110183 122110233chr7 140575899 140575949 chr7 141357856 141357906 chr7 144174277144174327 chr7 147590764 147590814 chr7 148079549 148079599 chr7152519241 152519291 chr8 16396670 16396720 chr8 26548620 26548670 chr826975212 26975262 chr8 29949657 29949707 chr8 34331248 34331298 chr836011683 36011733 chr8 39182303 39182353 chr8 50581777 50581827 chr852312750 52312800 chr11 125281717 125281767 chr8 58172206 58172256 chr858172838 58172888 chr8 58176618 58176668 chr8 59414931 59414981 chr869612615 69612665 chr8 69810987 69811037 chr8 74993381 74993431 chr891560020 91560070 chr8 105252639 105252689 chr8 112572399 112572449chr10 19046603 19046653 chr8 121524096 121524146 chr8 124448649124448699 chr8 127896769 127896819 chr8 132478742 132478792 chr8134741678 134741728 chr9 11055094 11055144 chr9 13228452 13228502 chr914820611 14820661 chr9 71697387 71697437 chr9 74614968 74615018 chr975065584 75065634 chr9 75658626 75658676 chr9 88994622 88994672 chr996015668 96015718 chr9 100782936 100782986 chr9 110011174 110011224 chr9129509269 129509319 chr10 21680676 21680726 chr5 69006205 69006255 chr569006678 69006728 chr5 69007232 69007282 chr5 69007287 69007337 chr570521542 70521592 chr5 70522244 70522294 chr5 70522471 70522521 chr1022580498 22580548 chr12 9677235 9677285 chr12 9827420 9827470 chr1212132185 12132235 chr12 14710205 14710255 chr12 28874937 28874987 chr1231696108 31696158 chr12 32066592 32066642 chr12 33027763 33027813 chr1239687416 39687466 chr12 48916670 48916720 chr12 62417673 62417723 chr1267796149 67796199 chr12 75768963 75769013 chr12 84843656 84843706 chr1291073369 91073419 chr12 103986948 103986998 chr12 103989301 103989351chr10 30446725 30446775 chr12 107670719 107670769 chr12 118227816118227866 chr10 32525560 32525610 chr12 126842488 126842538 chr1034476656 34476706 chr12 129786354 129786404 chr13 19297681 19297731chr13 21271904 21271954 chr10 35993736 35993786 chr13 23370363 23370413chr13 29760631 29760681 chr13 34739212 34739262 chr13 35134322 35134372chr13 44849427 44849477 chr13 48371143 48371193 chr13 58658405 58658455chr13 63830569 63830619 chr13 64140727 64140777 chr13 69394667 69394717chr13 76140648 76140698 chr13 95392261 95392311 chr13 108920104108920154 chr14 19766835 19766885 chr14 36681991 36682041 chr14 4452290844522958 chr14 48011068 48011118 chr14 50929235 50929285 chr14 5975789559757945 chr14 60315992 60316042 chr14 62205887 62205937 chr14 6438361864383668 chr14 66385315 66385365 chr14 80708678 80708728 chr14 9415185094151900 chr10 57926554 57926604 chr10 2318838 2318888 chr15 4355756543557615 chr15 50753758 50753808 chr15 78394988 78395038 chr15 8112612381126173 chr15 83050979 83051029 chr15 89641435 89641485 chr15 9174309491743144 chr15 96672873 96672923 chr16 7864320 7864370 chr16 81592558159305 chr16 11696445 11696495 chr16 11697535 11697585 chr16 1384022613840276 chr16 24456875 24456925 chr16 24473054 24473104 chr16 3530952635309576 chr16 59177054 59177104 chr16 63846061 63846111 chr16 7468116274681212 chr16 74967722 74967772 chr16 79670224 79670274 chr16 8366018183660231 chr17 7244614 7244664 chr17 12324096 12324146 chr17 1282313312823183 chr17 12824588 12824638 chr17 16649836 16649886 chr17 2157943921579489 chr17 26410035 26410085 chr17 30114599 30114649 Table 15BU.Repeat Category LTR9B chr10 90983283 90983333 chr18 13660988 13661038chr18 16910157 16910207 chr18 27576432 27576482 chr1 39857947 39857997chr1 55292584 55292634 chr1 185772310 185772360 chr1 193394775 193394825chr1 204998449 204998499 chr1 205083107 205083157 chr1 205082948205082998 chr1 225819978 225820028 chr1 229309751 229309801 chr1233721937 233721987 chr1 242390069 242390119 chr1 242390126 242390176chr20 12676491 12676541 chr20 34665989 34666039 chr20 42609553 42609603chr20 42610221 42610271 chr20 46837506 46837556 chr20 47118528 47118578chr20 52971069 52971119 chr20 52971713 52971763 chr21 17587571 17587621chr21 25136360 25136410 chr21 31934483 31934533 chr21 39198026 39198076chr21 44476192 44476242 chrX 3105577 3105627 chrX 26033665 26033715 chrX30393950 30394000 chrX 87783484 87783534 chrX 87789407 87789457 chrX101884039 101884089 chrX 107984908 107984958 chrX 111624328 111624378chrX 121651307 121651357 chrX 138718853 138718903 chrY 2532649 2532699chrY 2981340 2981390 chrY 4174253 4174303 chrY 20100026 20100076 chr230388405 30388455 chr2 53848462 53848512 chr2 89153971 89154021 chr2111541407 111541457 chr2 143675794 143675844 chr2 191186576 191186626chr2 192571583 192571633 chr2 203746179 203746229 chr2 207007232207007282 chr10 12408246 12408296 chr3 48242223 48242273 chr3 9769752397697573 chr3 121304032 121304082 chr3 136630758 136630808 chr3155101775 155101825 chr3 173715449 173715499 chr4 8245500 8245550 chr474230105 74230155 chr4 84574672 84574722 chr4 84575486 84575536 chr4110767182 110767232 chr4 111014484 111014534 chr4 134756686 134756736chr4 162750729 162750779 chr4 169315695 169315745 chr4 185868320185868370 chr4 185868686 185868736 chr4 185868922 185868972 chr4186552758 186552808 chr4 186552855 186552905 chr5 12714391 12714441 chr512715678 12715728 chr5 13888563 13888613 chr5 23271333 23271383 chr576268908 76268958 chr11 71858634 71858684 chr5 140863161 140863211 chr5157127398 157127448 chr5 157127970 157128020 chr5 157374093 157374143chr5 159150381 159150431 chr6 21762273 21762323 chr6 118946792 118946842chr6 123152233 123152283 chr6 138257269 138257319 chr6 141450396141450446 chr6 147750043 147750093 chr10 15936087 15936137 chr7 69945526994602 chr7 10692589 10692639 chr7 21880835 21880885 chr7 3490622234906272 chr7 43450030 43450080 chr7 63604713 63604763 chr7 101269111101269161 chr7 120631326 120631376 chr7 144174277 144174327 chr7147590764 147590814 chr7 152519241 152519291 chr8 29949657 29949707 chr869810987 69811037 chr8 124448649 124448699 chr9 14820611 14820661 chr996015668 96015718 chr12 9827420 9827470 chr12 28874937 28874987 chr1232066592 32066642 chr12 48916670 48916720 chr12 67796149 67796199 chr1275768963 75769013 chr12 84843656 84843706 chr12 103986948 103986998chr12 103989301 103989351 chr10 34476656 34476706 chr10 3599373635993786 chr13 23370363 23370413 chr13 29760631 29760681 chr13 3473921234739262 chr13 58658405 58658455 chr13 64140727 64140777 chr14 1976683519766885 chr14 64383618 64383668 chr14 66385315 66385365 chr14 8070867880708728 chr15 83050979 83051029 chr15 91743094 91743144 chr16 78643207864370 chr16 74967722 74967772 chr16 79670224 79670274 chr17 1232409612324146 chr17 16649836 16649886 chr17 26410035 26410085 Table 15BV.Repeat Category MER105 chr17 47464984 47465034 chr17 76677171 76677221chr10 104986758 104986808 chr19 60584278 60584328 chr1 8151882 8151932chr10 123865333 123865383 chr1 77854526 77854576 chr1 232399307232399357 chr21 21543126 21543176 chrX 69046204 69046254 chrX 123955784123955834 chr2 131934903 131934953 chr3 20792302 20792352 chr3 7915264379152693 chr4 114180583 114180633 chr5 5527186 5527236 chr5 8402869184028741 chr5 176325998 176326048 chr6 101178565 101178615 chr7 15394111539461 chr7 55030827 55030877 chr7 70975239 70975289 chr8 124893423124893473 chr9 34030443 34030493 chr9 125157153 125157203 chr9 136153727136153777 chr12 9571640 9571690 chr12 9913335 9913385 chr12 99131019913151 chr12 31207018 31207068 chr13 69927340 69927390 chr13 7614064876140698 chr14 81009416 81009466 chr10 74656398 74656448 chr17 37074373707487 chr17 3844580 3844630 chr17 4678606 4678656 Table 15BW. RepeatCategory MER115 chr17 40321357 40321407 chr17 47237392 47237442 chr1748490858 48490908 chr17 71985441 71985491 chr17 73707140 73707190 chr1775901543 75901593 chr18 2274999 2275049 chr18 4825187 4825237 chr185038026 5038076 chr18 12293149 12293199 chr18 12296070 12296120 chr1853396917 53396967 chr18 53396586 53396636 chr18 70064237 70064287 chr1873951577 73951627 chr19 44129557 44129607 chr10 107792814 107792864 chr123569183 23569233 chr10 122368143 122368193 chr10 122778365 122778415chr1 45980402 45980452 chr1 151547886 151547936 chr1 154789294 154789344chr1 158916456 158916506 chr1 178252869 178252919 chr1 198608493198608543 chr1 208787046 208787096 chr1 229119488 229119538 chr1230722606 230722656 chr10 131462310 131462360 chr1 245793997 245794047chr20 15003484 15003534 chr20 15003191 15003241 chr10 133108795133108845 chr20 25856108 25856158 chr20 31266702 31266752 chr20 3126768731267737 chr20 31267463 31267513 chr20 36878178 36878228 chr20 5558631455586364 chr20 58579067 58579117 chr20 58819322 58819372 chr21 3335018733350237 chr21 34858834 34858884 chr21 46576181 46576231 chr22 1561531515615365 chr22 20497056 20497106 chr22 35198392 35198442 chrX 138437754138437804 chr2 803011 803061 chr2 8490417 8490467 chr2 10375995 10376045chr2 11563286 11563336 chr2 15852580 15852630 chr11 18742927 18742977chr2 47542655 47542705 chr2 54915041 54915091 chr10 11789642 11789692chr2 68948350 68948400 chr2 73052612 73052662 chr2 85782669 85782719chr2 114025362 114025412 chr2 118378078 118378128 chr2 169804603169804653 chr2 188389269 188389319 chr2 193922667 193922717 chr2199825281 199825331 chr2 217166079 217166129 chr2 217166000 217166050chr2 240418962 240419012 chr2 240540928 240540978 chr3 24005272 24005322chr11 48987867 48987917 chr3 56440532 56440582 chr3 82545325 82545375chr3 85655475 85655525 chr3 101299974 101300024 chr3 137416811 137416861chr3 142496080 142496130 chr3 187568478 187568528 chr3 194119402194119452 chr3 198052923 198052973 chr4 80812226 80812276 chr4 9007834690078396 chr4 110014998 110015048 chr4 180358689 180358739 chr5 1577547315775523 chr5 66648730 66648780 chr5 130524278 130524328 chr5 173198883173198933 chr6 8620125 8620175 chr6 11416871 11416921 chr6 3116013031160180 chr11 85120211 85120261 chr6 158318218 158318268 chr7 12129871213037 chr7 26567365 26567415 chr11 118068431 118068481 chr11 118264175118264225 chr7 147575622 147575672 chr8 27801189 27801239 chr11124419065 124419115 chr8 39908626 39908676 chr8 83973237 83973287 chr895992948 95992998 chr8 105446505 105446555 chr8 126391075 126391125 chr8140744817 140744867 chr9 4023200 4023250 chr11 132201658 132201708 chr936869836 36869886 chr9 37475850 37475900 chr9 90654106 90654156 chr123288951 3289001 chr12 78325177 78325227 chr12 103802354 103802404 chr12105810948 105810998 chr12 111394884 111394934 chr12 114001951 114002001chr12 117993932 117993982 chr12 117993804 117993854 chr13 4687054946870599 chr13 47972108 47972158 chr14 22548547 22548597 chr14 4154601741546067 chr10 49729290 49729340 chr14 62717282 62717332 chr14 103259210103259260 chr14 103258930 103258980 chr14 103361622 103361672 chr14103361278 103361328 chr15 47088059 47088109 chr15 48811201 48811251chr15 51839385 51839435 chr15 75589502 75589552 chr15 77054920 77054970chr15 87965106 87965156 chr10 73415586 73415636 chr16 85150908 85150958chr10 76307542 76307592 chr10 77704876 77704926 Table 15BX. RepeatCategory MER11A* chr18 395798 395848 chr18 9493375 9493425 chr1870123608 70123658 chr1 46736143 46736193 chr10 131391175 131391225 chr2063274055 63274105 chr22 18297951 18298001 chrX 96535519 96535569 chr2106473008 106473058 chr2 242786781 242786831 chr11 47861546 47861596chr3 95004507 95004557 chr3 110623912 110623962 chr3 113882475 113882525chr3 150361875 150361925 chr3 197586983 197587033 chr3 199020693199020743 chr4 15897951 15898001 chr4 99792162 99792212 chr4 125843647125843697 chr4 132337813 132337863 chr4 136563840 136563890 chr4157396576 157396626 chr4 188199329 188199379 chr5 108699221 108699271chr5 125485237 125485287 chr5 163734727 163734777 chr5 180365018180365068 chr5 180714324 180714374 chr6 13936942 13936992 chr6 2527307225273122 chr6 90489024 90489074 chr7 52563479 52563529 chr7 127303810127303860 chr7 127485952 127486002 chr9 99527397 99527447 chr9 9952707499527124 chr12 55532980 55533030 chr13 43446756 43446806 chr10 3827586938275919 chr14 48272762 48272812 chr14 89280584 89280634 chr17 34427203442770 Table 15BY. Repeat Category MER11B chr17 66926261 66926311 chr1867239436 67239486 chr18 73025241 73025291 chr10 100682273 100682323chr10 101725121 101725171 chr19 12340427 12340477 chr19 2404986024049910 chr1 45456542 45456592 chr1 93889011 93889061 chr1 108374887108374937 chr1 169306448 169306498 chr1 204560439 204560489 chr1222132360 222132410 chr1 240188047 240188097 chr22 44469227 44469277chrX 6044455 6044505 chrX 15802783 15802833 chr11 6061449 6061499 chrX123389151 123389201 chr2 115689111 115689161 chr11 40856827 40856877chr3 15755242 15755292 chr3 20005014 20005064 chr5 127859815 127859865chr6 119421111 119421161 chr6 158669263 158669313 chr6 160411457160411507 chr6 160411752 160411802 chr7 96382598 96382648 chr7 9935295299353002 chr7 99353674 99353724 chr7 127824910 127824960 chr7 155800315155800365 chr8 79995327 79995377 chr8 108865069 108865119 chr9 2337990723379957 chr13 19507397 19507447 chr10 44812206 44812256 chr15 6698559766985647 chr10 71772615 71772665 chr16 57249633 57249683 Table 15BZ.Repeat Category MER11C chr17 40215259 40215309 chr17 63057560 63057610chr10 88278929 88278979 chr18 8612792 8612842 chr18 26647254 26647304chr18 31482049 31482099 chr18 41589423 41589473 chr18 65973109 65973159chr18 69333811 69333861 chr19 23693636 23693686 chr19 34380519 34380569chr19 40104065 40104115 chr19 43804696 43804746 chr19 43805380 43805430chr19 51362454 51362504 chr19 57101744 57101794 chr1 5520901 5520951chr1 45763285 45763335 chr1 103941933 103941983 chr1 108430247 108430297chr1 155379372 155379422 chr10 128154670 128154720 chr1 217643443217643493 chr20 25506559 25506609 chr21 27319436 27319486 chr21 3639182736391877 chr21 39368465 39368515 chr22 22623362 22623412 chr22 2265192222651972 chr22 25334962 25335012 chrX 15802783 15802833 chrX 1862758918627639 chrX 34176612 34176662 chrX 45603992 45604042 chrX 5156820651568256 chrX 106012830 106012880 chrX 120632211 120632261 chrX126692793 126692843 chrX 147351121 147351171 chrY 14994656 14994706 chr24811586 4811636 chr2 64008260 64008310 chr2 163586144 163586194 chr2203878570 203878620 chr2 211124870 211124920 chr2 211126480 211126530chr3 47508017 47508067 chr3 131493202 131493252 chr3 184939170 184939220chr11 62854917 62854967 chr11 62855792 62855842 chr3 197736445 197736495chr4 6183356 6183406 chr4 11732812 11732862 chr4 77533636 77533686 chr477534774 77534824 chr4 98853128 98853178 chr4 105228450 105228500 chr4110833796 110833846 chr4 154200689 154200739 chr11 67124496 67124546chr11 67386064 67386114 chr4 169112576 169112626 chr4 182747168182747218 chr5 19720869 19720919 chr5 33890040 33890090 chr5 4307109543071145 chr5 44284681 44284731 chr5 54187198 54187248 chr5 7337415373374203 chr11 71188457 71188507 chr5 107686727 107686777 chr5 142827330142827380 chr6 2873253 2873303 chr6 11036445 11036495 chr6 3083838530838435 chr6 33931078 33931128 chr6 57431704 57431754 chr6 106108380106108430 chr11 94021425 94021475 chr6 114665355 114665405 chr6114665210 114665260 chr6 115056135 115056185 chr6 115807598 115807648chr6 119856578 119856628 chr6 145998698 145998748 chr7 7411305 7411355chr7 12545347 12545397 chr7 35757640 35757690 chr7 50655591 50655641chr7 56073557 56073607 chr7 63253664 63253714 chr7 79817993 79818043chr7 97114553 97114603 chr7 104898292 104898342 chr7 108468537 108468587chr7 111450719 111450769 chr8 13566180 13566230 chr8 56035916 56035966chr8 63035667 63035717 chr8 80032401 80032451 chr8 82709657 82709707chr8 144227485 144227535 chr9 23379197 23379247 chr9 23379907 23379957chr9 24229494 24229544 chr9 63360136 63360186 chr9 78444516 78444566chr9 82114052 82114102 chr9 89732147 89732197 chr12 30218365 30218415chr12 82998661 82998711 chr12 83004551 83004601 chr12 120131073120131123 chr13 24043113 24043163 chr13 46580598 46580648 chr10 3872052838720578 chr13 86994951 86995001 chr14 20189565 20189615 chr14 3999959739999647 chr14 53630908 53630958 chr14 61238264 61238314 chr10 5610389456103944 chr14 105157464 105157514 chr15 22126981 22127031 chr1522297882 22297932 chr15 22335025 22335075 chr15 22966262 22966312 chr1585052003 85052053 chr15 90249504 90249554 chr15 98825703 98825753 chr1598827228 98827278 chr15 98826963 98827013 chr16 3969546 3969596 chr1071146877 71146927 chr16 14025531 14025581 chr16 21306847 21306897 chr1078841864 78841914 Table 15CA. Repeat Category MER11D chr10 9636335596363405 chr10 96363504 96363554 chr19 48096167 48096217 chrX 75331787533228 chrX 41918905 41918955 chrX 147339823 147339873 chr2 101481794101481844 chr2 211498285 211498335 chr3 20937962 20938012 chr4 5960043159600481 chr4 88671024 88671074 chr4 137244525 137244575 chr4 161755105161755155 chr5 153480858 153480908 chr5 176353627 176353677 chr649515803 49515853 chr6 49523035 49523085 chr6 66395799 66395849 chr6121344741 121344791 chr6 121351123 121351173 chr6 145435536 145435586chr6 158230742 158230792 chr7 2212051 2212101 chr7 30290910 30290960chr7 86955980 86956030 chr7 86956387 86956437 chr7 93112121 93112171chr7 96838755 96838805 chr8 125935178 125935228 chr8 135257317 135257367chr9 3100923 3100973 chr12 110844055 110844105 chr13 21356076 21356126chr14 45989898 45989948 chr10 54621911 54621961 chr14 94878274 94878324chr17 7272463 7272513 Table 15CB. Repeat Category MER34B chr17 5077201850772068 chr10 85528575 85528625 chr17 57252259 57252309 chr17 6288983662889886 chr17 75209408 75209458 chr17 79478135 79478185 chr18 5521016855210218 chr19 7461027 7461077 chr19 7461625 7461675 chr10 118414968118415018 chr1 17188473 17188523 chr1 23828344 23828394 chr1 3090052230900572 chr1 45310060 45310110 chr1 61877136 61877186 chr1 112733012112733062 chr1 112862899 112862949 chr1 201129540 201129590 chr1225634096 225634146 chr20 23045760 23045810 chr10 133729744 133729794chr11 328409 328459 chr21 44550269 44550319 chr22 19716208 19716258chr22 31819188 31819238 chrX 2633634 2633684 chrX 15301217 15301267 chrX15348726 15348776 chrX 35358799 35358849 chrX 42427669 42427719 chrX88072742 88072792 chrX 88082370 88082420 chrX 111818994 111819044 chrX144620279 144620329 chr2 1366082 1366132 chr2 1365917 1365967 chr227203643 27203693 chr2 42702253 42702303 chr2 47266649 47266699 chr247653771 47653821 chr2 62553370 62553420 chr2 70456953 70457003 chr270458976 70459026 chr2 82305011 82305061 chr2 233657661 233657711 chr2239143385 239143435 chr2 243024320 243024370 chr3 20086557 20086607 chr340266232 40266282 chr3 61224280 61224330 chr3 63790429 63790479 chr383263423 83263473 chr3 99178056 99178106 chr3 105560607 105560657 chr3149844097 149844147 chr3 161143719 161143769 chr3 168907006 168907056chr3 173064249 173064299 chr3 176366136 176366186 chr4 764196 764246chr4 2807281 2807331 chr4 2808633 2808683 chr4 4271387 4271437 chr416756591 16756641 chr11 65027004 65027054 chr4 57394558 57394608 chr457417782 57417832 chr4 61590133 61590183 chr4 68216689 68216739 chr4144736093 144736143 chr4 162370813 162370863 chr4 189385448 189385498chr4 189386833 189386883 chr5 105536991 105537041 chr5 116194075116194125 chr5 119011110 119011160 chr5 142055119 142055169 chr5149296808 149296858 chr5 178555574 178555624 chr6 27895395 27895445 chr680114928 80114978 chr6 110950036 110950086 chr6 144629720 144629770 chr6160443747 160443797 chr6 160444042 160444092 chr6 166747426 166747476chr7 77220567 77220617 chr7 140077267 140077317 chr7 142289936 142289986chr7 147695838 147695888 chr8 23059240 23059290 chr8 30008238 30008288chr8 53913511 53913561 chr10 19806204 19806254 chr10 19808787 19808837chr9 68875769 68875819 chr9 86385437 86385487 chr9 110835742 110835792chr12 31389923 31389973 chr12 31918372 31918422 chr12 74452319 74452369chr12 116041042 116041092 chr13 28345729 28345779 chr13 4779890847798958 chr10 44658317 44658367 chr10 44658680 44658730 chr10 4465883444658884 chr10 44659150 44659200 chr14 19298418 19298468 chr14 6382724863827298 chr14 65575053 65575103 chr14 67315861 67315911 chr14 8859897788599027 chr16 9210344 9210394 chr16 48295737 48295787 chr16 8482635484826404 Table 15CC. Repeat Category MER34B-int chr10 85528575 85528625chr10 118414968 118415018 chr1 30900522 30900572 chr1 45310060 45310110chr1 112733012 112733062 chr11 328409 328459 chr22 19716208 19716258chrX 15348726 15348776 chrX 88082370 88082420 chr3 40266232 40266282chr3 63790429 63790479 chr3 83263423 83263473 chr3 99178056 99178106chr3 105560607 105560657 chr3 149844097 149844147 chr3 161143719161143769 chr3 173064249 173064299 chr4 2807281 2807331 chr4 28086332808683 chr4 61590133 61590183 chr4 144736093 144736143 chr4 189385448189385498 chr4 189386833 189386883 chr5 105536991 105537041 chr5149296808 149296858 chr6 110950036 110950086 chr7 140077267 140077317chr7 142289936 142289986 chr8 23059240 23059290 chr10 19806204 19806254chr10 19808787 19808837 Table 15CD. Repeat Category MER34C chr1827651163 27651213 chr18 32807414 32807464 chr19 505773 505823 chr1948590743 48590793 chr1 2185443 2185493 chr1 2185916 2185966 chr1 33580063358056 chr1 9421164 9421214 chr10 121298838 121298888 chr1 178048424178048474 chr1 225800182 225800232 chr1 235676212 235676262 chr1244905815 244905865 chr20 20793502 20793552 chr20 25219964 25220014chr20 31048153 31048203 chr21 33672436 33672486 chr21 40038539 40038589chr21 40039052 40039102 chr21 41801469 41801519 chr21 42920610 42920660chr21 43273409 43273459 chr11 1887412 1887462 chr22 46199928 46199978chrX 2409324 2409374 chrX 14329409 14329459 chrX 42073388 42073438 chrX42233616 42233666 chrX 66549011 66549061 chrX 72638840 72638890 chr22881570 2881620 chr2 33603088 33603138 chr2 62077281 62077331 chr264651812 64651862 chr2 64651543 64651593 chr2 65334024 65334074 chr2116687468 116687518 chr2 128773443 128773493 chr2 231613616 231613666chr3 48102261 48102311 chr3 78291680 78291730 chr3 96302937 96302987chr3 106648615 106648665 chr11 63512975 63513025 chr4 139611876139611926 chr4 188077113 188077163 chr4 188103705 188103755 chr579637631 79637681 chr5 79638442 79638492 chr6 3749470 3749520 chr610767197 10767247 chr6 29670908 29670958 chr10 912747 912797 chr6139614599 139614649 chr6 145498033 145498083 chr6 158792646 158792696chr7 283585 283635 chr7 32716676 32716726 chr7 32722959 32723009 chr744773074 44773124 chr7 96567310 96567360 chr7 154228662 154228712 chr7158544874 158544924 chr8 42133638 42133688 chr8 125328895 125328945 chr96656012 6656062 chr9 75346148 75346198 chr9 129840359 129840409 chr1211661097 11661147 chr10 23749942 23749992 chr12 25996105 25996155 chr1269180898 69180948 chr12 96089450 96089500 chr13 57373738 57373788 chr1048936967 48937017 chr14 42271864 42271914 chr15 23548830 23548880 chr1064381632 64381682 chr10 64381964 64382014 chr15 72004387 72004437 chr1573039491 73039541 chr15 90416999 90417049 chr10 69817367 69817417 chr1599003367 99003417 chr16 11639845 11639895 chr10 72420232 72420282 chr1665582870 65582920 chr16 85148745 85148795 chr17 19021621 19021671 Table15CE. Repeat Category MER41E chr18 40429096 40429146 chr19 60933446093394 chr19 9909357 9909407 chr19 54072893 54072943 chr19 5491946454919514 chr1 8853924 8853974 chr1 12399761 12399811 chr1 2695363326953683 chr1 26959682 26959732 chr1 156263561 156263611 chr1 156263349156263399 chr1 173671809 173671859 chr1 173671518 173671568 chr2062865293 62865343 chr11 294389 294439 chr21 45290705 45290755 chr1126339496 26339546 chr2 219846914 219846964 chr3 101387573 101387623 chr426230853 26230903 chr4 179137300 179137350 chr5 32549469 32549519 chr5108034929 108034979 chr11 93760921 93760971 chr6 150278259 150278309chr6 150278742 150278792 chr6 153773856 153773906 chr8 8788828 8788878chr9 112720735 112720785 chr9 119358141 119358191 chr12 8209277882092828 chr12 116967454 116967504 chr13 77131165 77131215 chr1628481543 28481593 chr16 28481664 28481714 chr16 28494480 28494530 Table15CF. Repeat Category MER44C chr17 57338431 57338481 chr17 6698656566986615 chr18 13172025 13172075 chr19 43014963 43015013 chr19 4469281544692865 chr19 58773213 58773263 chr1 216980108 216980158 chr20 4351281343512863 chr20 46168018 46168068 chr20 61549805 61549855 chr21 1620242016202470 chr21 24077042 24077092 chrX 70444460 70444510 chr2 855052855102 chr2 32623921 32623971 chr2 108965316 108965366 chr2 175045479175045529 chr2 219607366 219607416 chr2 232024654 232024704 chr3124478624 124478674 chr10 750879 750929 chr3 184229947 184229997 chr424601112 24601162 chr4 33532047 33532097 chr4 107678276 107678326 chr572129201 72129251 chr5 124501633 124501683 chr5 179641912 179641962 chr6414730 414780 chr6 76241121 76241171 chr6 167817173 167817223 chr11111352203 111352253 chr7 36228486 36228536 chr7 37111702 37111752 chr11115852809 115852859 chr7 158017852 158017902 chr7 158018711 158018761chr8 6349354 6349404 chr8 61693573 61693623 chr8 61693064 61693114 chr11128550972 128551022 chr8 143050292 143050342 chr9 70858163 70858213chr10 24433461 24433511 chr12 36236507 36236557 chr12 75959292 75959342chr12 130527959 130528009 chr14 89681331 89681381 chr14 8968368889683738 chr15 25316700 25316750 chr15 29139022 29139072 chr15 4178871841788768 chr15 68798226 68798276 chr15 99950295 99950345 chr16 5917705459177104 chr17 3087684 3087734 chr17 7877570 7877620 Table 15CG. RepeatCategory MER44D chr17 54862299 54862349 chr19 36679035 36679085 chr1151620384 151620434 chr1 158302000 158302050 chr20 377409 377459 chrX19089812 19089862 chr2 480144 480194 chr2 5464063 5464113 chr2 113655772113655822 chr2 158731338 158731388 chr11 47951940 47951990 chr3121012704 121012754 chr4 68337394 68337444 chr4 68337298 68337348 chr499697671 99697721 chr4 182162455 182162505 chr4 182162606 182162656 chr5175477133 175477183 chr5 177555509 177555559 chr6 158952653 158952703chr7 32379009 32379059 chr8 70739998 70740048 chr8 122745740 122745790chr9 28780615 28780665 chr9 30012363 30012413 chr12 49945837 49945887chr16 50530109 50530159 chr16 88404077 88404127 chr10 80137221 80137271chr10 80555868 80555918 Table 15CH. Repeat Category MER4A1 chr1749870706 49870756 chr17 51481669 51481719 chr10 86302391 86302441 chr1088455635 88455685 chr17 73317152 73317202 chr17 75698321 75698371 chr1780704216 80704266 chr17 80811888 80811938 chr17 80813179 80813229 chr1818902000 18902050 chr18 55496602 55496652 chr18 72616008 72616058 chr19455691 455741 chr19 9026003 9026053 chr19 16279737 16279787 chr1941612521 41612571 chr19 43051386 43051436 chr10 105353082 105353132chr19 48640952 48641002 chr19 56115985 56116035 chr19 56572072 56572122chr19 57988082 57988132 chr19 63021095 63021145 chr19 63121278 63121328chr1 13188928 13188978 chr1 22778772 22778822 chr1 44059871 44059921chr1 45184264 45184314 chr1 66749264 66749314 chr1 105753294 105753344chr1 106420268 106420318 chr1 114203059 114203109 chr10 128103409128103459 chr1 177743560 177743610 chr1 199241864 199241914 chr1215245164 215245214 chr1 217947911 217947961 chr1 217952712 217952762chr1 220253922 220253972 chr1 224010707 224010757 chr1 226331919226331969 chr1 244215327 244215377 chr20 8745891 8745941 chr20 2561521925615269 chr20 53962566 53962616 chr21 19045384 19045434 chr21 1927788819277938 chr21 24177822 24177872 chr21 32453303 32453353 chr21 4323993343239983 chr21 43241599 43241649 chr21 43244130 43244180 chr21 4502320245023252 chr22 14693356 14693406 chr11 3097660 3097710 chr22 4618736546187415 chr22 47419707 47419757 chr22 49126260 49126310 chr22 4921655749216607 chrX 2377667 2377717 chrX 5007930 5007980 chrX 2261554922615599 chrX 27702543 27702593 chrX 31908873 31908923 chrX 4251417142514221 chr11 7955709 7955759 chrX 70784660 70784710 chrX 7746225677462306 chrX 78416582 78416632 chrX 86495599 86495649 chrX 9016057790160627 chrX 91597227 91597277 chrX 92077828 92077878 chrX 9851724698517296 chrX 113140416 113140466 chrX 114835369 114835419 chrX118121177 118121227 chrX 121680850 121680900 chrX 144189263 144189313chrX 144610443 144610493 chrX 144615032 144615082 chrY 3576941 3576991chrY 13522685 13522735 chrY 13599141 13599191 chrY 13710408 13710458chrY 13804461 13804511 chr2 721783 721833 chr2 1793728 1793778 chr22898828 2898878 chr2 2953485 2953535 chr2 2955905 2955955 chr2 30411613041211 chr2 8864628 8864678 chr2 20484867 20484917 chr2 2381119623811246 chr2 25282122 25282172 chr2 42975071 42975121 chr2 4297658342976633 chr2 84733253 84733303 chr2 85584112 85584162 chr11 3128348431283534 chr2 108633115 108633165 chr2 108634777 108634827 chr2110194303 110194353 chr2 113703067 113703117 chr2 113709135 113709185chr2 127792644 127792694 chr2 131103790 131103840 chr2 132363106132363156 chr2 209211056 209211106 chr2 235134244 235134294 chr2243039826 243039876 chr2 243044475 243044525 chr3 16692885 16692935 chr327507094 27507144 chr3 50309759 50309809 chr3 53270082 53270132 chr367639578 67639628 chr3 67639388 67639438 chr11 58370735 58370785 chr3116223969 116224019 chr3 127305289 127305339 chr11 60915634 60915684chr10 12813826 12813876 chr3 159666818 159666868 chr3 163282145163282195 chr3 198453535 198453585 chr4 479935 479985 chr4 480108 480158chr4 482044 482094 chr4 3095514 3095564 chr4 5826248 5826298 chr47224898 7224948 chr4 15453891 15453941 chr4 20389016 20389066 chr443800982 43801032 chr4 93405249 93405299 chr4 93410676 93410726 chr497310234 97310284 chr4 109273090 109273140 chr4 141176834 141176884 chr4162765339 162765389 chr11 67216071 67216121 chr4 166921791 166921841chr4 169198637 169198687 chr4 185942047 185942097 chr4 189392162189392212 chr5 6437024 6437074 chr5 13573632 13573682 chr5 2116207821162128 chr5 27338460 27338510 chr5 43032960 43033010 chr5 4323375643233806 chr5 74665846 74665896 chr5 175838814 175838864 chr5 180659955180660005 chr6 30588169 30588219 chr11 85372152 85372202 chr6 6353239263532442 chr6 131297278 131297328 chr6 153761283 153761333 chr6167637195 167637245 chr6 167637718 167637768 chr6 167637769 167637819chr6 169998023 169998073 chr7 38328301 38328351 chr7 56043416 56043466chr7 63775192 63775242 chr7 68357469 68357519 chr7 69894851 69894901chr7 70819583 70819633 chr7 72670749 72670799 chr7 112819615 112819665chr7 139596381 139596431 chr7 148669600 148669650 chr7 157648787157648837 chr8 3970418 3970468 chr8 4539613 4539663 chr8 6724752 6724802chr8 6725029 6725079 chr8 23119513 23119563 chr8 39966635 39966685 chr859414931 59414981 chr8 64313726 64313776 chr8 82456770 82456820 chr8120686232 120686282 chr8 122552822 122552872 chr8 134204317 134204367chr8 143789526 143789576 chr9 93433855 93433905 chr9 97152388 97152438chr9 108456446 108456496 chr12 670818 670868 chr9 128841920 128841970chr12 26129464 26129514 chr12 32056411 32056461 chr12 38870377 38870427chr12 94284872 94284922 chr12 99558590 99558640 chr10 36737830 36737880chr13 28122798 28122848 chr13 39644975 39645025 chr10 38154790 38154840chr13 43820304 43820354 chr13 48366584 48366634 chr13 60644354 60644404chr13 65753901 65753951 chr13 76494235 76494285 chr13 97020784 97020834chr13 97536085 97536135 chr13 97537238 97537288 chr10 43237791 43237841chr14 21286271 21286321 chr14 21662333 21662383 chr10 50884375 50884425chr14 65713847 65713897 chr14 68196947 68196997 chr14 68203701 68203751chr14 68770504 68770554 chr14 78347776 78347826 chr14 88804268 88804318chr14 90055443 90055493 chr14 98456404 98456454 chr14 99767723 99767773chr14 100134095 100134145 chr14 100135688 100135738 chr14 100513259100513309 chr14 103497584 103497634 chr14 104410535 104410585 chr1523927470 23927520 chr15 31600999 31601049 chr15 43478158 43478208 chr1549435332 49435382 chr15 64472013 64472063 chr15 64477549 64477599 chr1568787964 68788014 chr15 91450470 91450520 chr16 10377029 10377079 chr1612674886 12674936 chr16 17003180 17003230 chr16 19932804 19932854 chr1630582293 30582343 chr16 31731702 31731752 chr16 60010678 60010728 chr103171148 3171198 chr16 63401241 63401291 chr16 71856279 71856329 chr1674934900 74934950 chr16 74942548 74942598 chr16 83774144 83774194 chr1683775916 83775966 chr16 85750104 85750154 chr16 85750812 85750862 chr1687598236 87598286 chr10 76311073 76311123 chr10 77922992 77923042 chr103655613 3655663 Table 15CI. Repeat Category MER4D chr10 8262181682621866 chr17 49870706 49870756 chr10 85586493 85586543 chr17 7495800374958053 chr17 77188634 77188684 chr17 78828710 78828760 chr17 8139176481391814 chr18 646397 646447 chr18 8209095 8209145 chr18 8930095 8930145chr18 11580210 11580260 chr18 19487725 19487775 chr18 25749634 25749684chr18 32778894 32778944 chr18 58501240 58501290 chr18 60229610 60229660chr18 70768005 70768055 chr10 98986394 98986444 chr10 99058382 99058432chr19 9146080 9146130 chr19 9773837 9773887 chr19 11787797 11787847chr19 11860077 11860127 chr19 11897388 11897438 chr19 11937330 11937380chr19 11937572 11937622 chr19 11962301 11962351 chr19 12127291 12127341chr19 12472046 12472096 chr19 15045182 15045232 chr19 40722445 40722495chr10 104642279 104642329 chr19 51372795 51372845 chr19 5623983556239885 chr19 62375436 62375486 chr1 227716 227766 chr1 3498101 3498151chr1 20034698 20034748 chr1 32779858 32779908 chr1 75950522 75950572chr1 109129891 109129941 chr1 171958676 171958726 chr1 200125039200125089 chr10 131670828 131670878 chr10 131994969 131995019 chr1239356917 239356967 chr1 245993147 245993197 chr20 3352300 3352350 chr205730321 5730371 chr10 133573984 133574034 chr20 35241564 35241614 chr2049945522 49945572 chr10 134140180 134140230 chr10 134199156 134199206chr20 53936656 53936706 chr10 134251419 134251469 chr20 6258605962586109 chr20 63482161 63482211 chr11 291673 291723 chr11 294389 294439chr11 296451 296501 chr21 44491513 44491563 chr21 44528618 44528668chr21 45023202 45023252 chr11 1749675 1749725 chr11 1750237 1750287chr11 1751395 1751445 chr22 30892716 30892766 chr22 37544103 37544153chr11 2384001 2384051 chr22 47304715 47304765 chr11 3225141 3225191chr11 3232339 3232389 chrX 2424897 2424947 chrX 2554743 2554793 chrX2559458 2559508 chrX 4099109 4099159 chr11 4144267 4144317 chrX 4545712745457177 chrX 73201982 73202032 chrX 78723449 78723499 chrX 101035525101035575 chrX 151195123 151195173 chr2 9339807 9339857 chr2 2736297627363026 chr2 32271956 32272006 chr2 39566945 39566995 chr2 5851364558513695 chr2 70394704 70394754 chr2 71575369 71575419 chr2 8915397189154021 chr2 109342265 109342315 chr2 113435500 113435550 chr2125518807 125518857 chr2 127343481 127343531 chr2 129071332 129071382chr2 161185602 161185652 chr2 189496924 189496974 chr2 202850093202850143 chr2 207467114 207467164 chr2 218277236 218277286 chr2229681901 229681951 chr2 232637365 232637415 chr2 234096260 234096310chr2 242102644 242102694 chr3 8185018 8185068 chr3 40477875 40477925chr3 40478741 40478791 chr3 40493720 40493770 chr3 41966143 41966193chr3 41966905 41966955 chr3 48116258 48116308 chr3 80803645 80803695chr3 97799904 97799954 chr3 126632907 126632957 chr3 129700217 129700267chr3 130438662 130438712 chr3 139460807 139460857 chr3 143908454143908504 chr3 150277209 150277259 chr11 61645572 61645622 chr3155873727 155873777 chr3 180507235 180507285 chr3 186302236 186302286chr3 188059131 188059181 chr4 8558870 8558920 chr4 18982233 18982283chr4 31858852 31858902 chr4 57039387 57039437 chr4 65138773 65138823chr4 78463019 78463069 chr4 85028201 85028251 chr11 65992489 65992539chr4 109566311 109566361 chr4 115837183 115837233 chr4 136752614136752664 chr4 149022633 149022683 chr4 152591322 152591372 chr4173261016 173261066 chr4 184573979 184574029 chr4 188100756 188100806chr5 922738 922788 chr5 1200075 1200125 chr5 18580782 18580832 chr521133342 21133392 chr5 79684054 79684104 chr5 85190623 85190673 chr589922844 89922894 chr5 104579739 104579789 chr5 128806264 128806314chr10 14696007 14696057 chr6 15674542 15674592 chr11 79339197 79339247chr6 21826055 21826105 chr6 26584520 26584570 chr6 27891793 27891843chr6 123889807 123889857 chr6 136369977 136370027 chr6 158028345158028395 chr6 158518206 158518256 chr6 167561007 167561057 chr7 233703233753 chr7 12313752 12313802 chr7 23953975 23954025 chr7 3950111239501162 chr7 44893002 44893052 chr7 66143928 66143978 chr7 6639608766396137 chr7 66636502 66636552 chr7 71425048 71425098 chr7 7472846274728512 chr7 100136893 100136943 chr7 110843993 110844043 chr7128177499 128177549 chr7 137984278 137984328 chr11 118608749 118608799chr7 147615956 147616006 chr7 156138911 156138961 chr7 156315764156315814 chr7 156314878 156314928 chr7 158357113 158357163 chr8 510959511009 chr8 1694880 1694930 chr8 2218028 2218078 chr8 2217974 2218024chr8 11885993 11886043 chr8 18259074 18259124 chr8 18258935 18258985chr8 41586701 41586751 chr11 124943555 124943605 chr8 54723539 54723589chr8 75468140 75468190 chr8 101800524 101800574 chr8 114484292 114484342chr8 120134224 120134274 chr8 144387871 144387921 chr8 145333224145333274 chr9 37741692 37741742 chr9 37743608 37743658 chr9 6709538967095439 chr9 69667346 69667396 chr9 72164587 72164637 chr9 9442217694422226 chr9 96992635 96992685 chr9 97810507 97810557 chr9 126222179126222229 chr9 132224508 132224558 chr9 132225400 132225450 chr1231923319 31923369 chr12 55382715 55382765 chr12 74551747 74551797 chr1297385071 97385121 chr12 101052072 101052122 chr12 104524039 104524089chr12 122983724 122983774 chr12 126918758 126918808 chr12 130059965130060015 chr10 35238757 35238807 chr13 34660434 34660484 chr13 3513432235134372 chr13 39464835 39464885 chr13 111322774 111322824 chr13111883466 111883516 chr13 112387742 112387792 chr13 112879941 112879991chr14 32280572 32280622 chr14 48009425 48009475 chr15 87211979 87212029chr16 743625 743675 chr16 767689 767739 chr16 3769164 3769214 chr1610851196 10851246 chr16 24423044 24423094 chr16 48322132 48322182 chr10397536 397586 chr16 65767611 65767661 chr16 68051722 68051772 chr1668508183 68508233 chr16 74804551 74804601 chr16 84828681 84828731 chr1687676103 87676153 chr16 87676000 87676050 chr17 7045807 7045857 chr1719575870 19575920 chr17 21175835 21175885 chr17 26927387 26927437 chr1081487637 81487687 Table 15CJ. Repeat Category MER4D1 chr10 8558649385586543 chr17 77188634 77188684 chr17 81391764 81391814 chr18 646397646447 chr18 8930095 8930145 chr18 32778894 32778944 chr10 9905838299058432 chr19 9146080 9146130 chr19 9773837 9773887 chr19 1504518215045232 chr19 40722445 40722495 chr10 104642279 104642329 chr1962375436 62375486 chr1 227716 227766 chr1 3498101 3498151 chr1 2003469820034748 chr1 75950522 75950572 chr1 109129891 109129941 chr1 171958676171958726 chr10 131994969 131995019 chr20 3352300 3352350 chr20 3524156435241614 chr10 134140180 134140230 chr20 53936656 53936706 chr10134251419 134251469 chr20 62586059 62586109 chr22 30892716 30892766chr11 2384001 2384051 chr11 3225141 3225191 chr11 3232339 3232389 chrX2554743 2554793 chrX 2559458 2559508 chrX 78723449 78723499 chrX151195123 151195173 chr2 9339807 9339857 chr2 32271956 32272006 chr239566945 39566995 chr2 127343481 127343531 chr2 129071332 129071382 chr2161185602 161185652 chr2 207467114 207467164 chr2 229681901 229681951chr2 234096260 234096310 chr2 242102644 242102694 chr3 40477875 40477925chr3 40478741 40478791 chr3 41966143 41966193 chr3 41966905 41966955chr3 48116258 48116308 chr3 97799904 97799954 chr3 126632907 126632957chr3 130438662 130438712 chr3 139460807 139460857 chr3 143908454143908504 chr3 150277209 150277259 chr3 180507235 180507285 chr418982233 18982283 chr4 31858852 31858902 chr4 57039387 57039437 chr478463019 78463069 chr11 65992489 65992539 chr4 115837183 115837233 chr4152591322 152591372 chr4 173261016 173261066 chr5 18580782 18580832 chr579684054 79684104 chr5 85190623 85190673 chr10 14696007 14696057 chr1179339197 79339247 chr6 21826055 21826105 chr6 26584520 26584570 chr6136369977 136370027 chr6 158028345 158028395 chr6 158518206 158518256chr7 23953975 23954025 chr7 66143928 66143978 chr7 66636502 66636552chr7 71425048 71425098 chr7 100136893 100136943 chr11 118608749118608799 chr7 147615956 147616006 chr7 156138911 156138961 chr7156315764 156315814 chr7 156314878 156314928 chr8 1694880 1694930 chr11124943555 124943605 chr8 75468140 75468190 chr9 67095389 67095439 chr969667346 69667396 chr9 94422176 94422226 chr9 126222179 126222229 chr1274551747 74551797 chr12 97385071 97385121 chr12 101052072 101052122chr12 104524039 104524089 chr12 126918758 126918808 chr10 3523875735238807 chr13 35134322 35134372 chr13 39464835 39464885 chr13 112879941112879991 chr14 32280572 32280622 chr16 3769164 3769214 chr16 1085119610851246 chr10 397536 397586 chr16 68051722 68051772 chr16 8482868184828731 chr17 7045807 7045857 chr17 19575870 19575920 chr17 2692738726927437 chr10 81487637 81487687 Table 15CK. Repeat Category MER50 chr1740475514 40475564 chr17 53884816 53884866 chr17 58107096 58107146 chr1762870332 62870382 chr10 87963270 87963320 chr17 67083099 67083149 chr1767085464 67085514 chr17 67086764 67086814 chr17 74975548 74975598 chr1777211706 77211756 chr18 566669 566719 chr18 11574668 11574718 chr1811893485 11893535 chr18 27621381 27621431 chr18 47434648 47434698 chr1097647539 97647589 chr18 54624629 54624679 chr18 56875379 56875429 chr1857784078 57784128 chr18 58260787 58260837 chr18 66066645 66066695 chr1866258530 66258580 chr18 71804744 71804794 chr10 5477194 5477244 chr197745018 7745068 chr19 34823147 34823197 chr19 35085381 35085431 chr10104315655 104315705 chr19 43056431 43056481 chr10 5820538 5820588 chr10109024049 109024099 chr10 110812158 110812208 chr19 53193503 53193553chr10 113528085 113528135 chr19 59041021 59041071 chr1 953470 953520chr1 955570 955620 chr1 4142427 4142477 chr1 4142178 4142228 chr15588551 5588601 chr1 16879489 16879539 chr1 21181175 21181225 chr10122195791 122195841 chr10 122195339 122195389 chr1 51443031 51443081chr1 75540050 75540100 chr1 91092173 91092223 chr1 113878663 113878713chr1 166324713 166324763 chr1 166324524 166324574 chr1 168634712168634762 chr1 170880426 170880476 chr1 171313647 171313697 chr1180102022 180102072 chr1 181371002 181371052 chr1 209379148 209379198chr1 221770585 221770635 chr1 226097278 226097328 chr1 231740697231740747 chr1 231880229 231880279 chr1 231880683 231880733 chr1231880831 231880881 chr1 233162664 233162714 chr1 238262350 238262400chr1 238366933 238366983 chr20 36868801 36868851 chr20 37657210 37657260chr20 46088016 46088066 chr20 50559574 50559624 chr20 53754419 53754469chr20 59797353 59797403 chr21 18019066 18019116 chr21 20996422 20996472chr21 21375745 21375795 chr21 22873116 22873166 chr21 24958013 24958063chr21 29486042 29486092 chr21 29486429 29486479 chr21 36406379 36406429chr21 42915781 42915831 chr21 44493151 44493201 chr21 44751827 44751877chr22 21702098 21702148 chr22 22389230 22389280 chr22 22390769 22390819chr22 31279946 31279996 chr22 31281147 31281197 chr22 34833896 34833946chr10 9924602 9924652 chr22 43536939 43536989 chr22 43541654 43541704chrX 4800824 4800874 chrX 8346003 8346053 chrX 14429276 14429326 chrX15407411 15407461 chrX 46285807 46285857 chrX 86117641 86117691 chrX86129602 86129652 chrX 86586306 86586356 chrX 88602663 88602713 chrX96318456 96318506 chr11 9992783 9992833 chrX 124980125 124980175 chrX129601377 129601427 chrX 143048066 143048116 chrX 143694000 143694050chrX 144926632 144926682 chrX 150986787 150986837 chrY 3724548 3724598chr2 813473 813523 chr2 7255905 7255955 chr2 7259220 7259270 chr210713571 10713621 chr2 12372624 12372674 chr2 13036364 13036414 chr229288848 29288898 chr2 30308884 30308934 chr2 37626244 37626294 chr1120772386 20772436 chr11 21768694 21768744 chr2 56542682 56542732 chr261107046 61107096 chr2 61993416 61993466 chr11 26088559 26088609 chr272291892 72291942 chr2 76616916 76616966 chr2 77982071 77982121 chr2101597281 101597331 chr2 101923598 101923648 chr2 116700997 116701047chr2 121943323 121943373 chr2 129070564 129070614 chr2 129071332129071382 chr2 138630897 138630947 chr2 139205273 139205323 chr2140648849 140648899 chr2 169846117 169846167 chr2 169845855 169845905chr2 186562952 186563002 chr2 194557380 194557430 chr2 196984680196984730 chr2 198439386 198439436 chr2 201934867 201934917 chr2204999799 204999849 chr2 217182228 217182278 chr2 228239538 228239588chr2 228848729 228848779 chr2 232507178 232507228 chr3 9605152 9605202chr3 16117645 16117695 chr3 16233185 16233235 chr3 19147900 19147950chr3 33471139 33471189 chr3 45319611 45319661 chr3 47706294 47706344chr3 50031815 50031865 chr3 53904824 53904874 chr3 57904887 57904937chr3 60674238 60674288 chr11 57407129 57407179 chr3 100016954 100017004chr3 104206050 104206100 chr3 104206790 104206840 chr3 105560607105560657 chr3 127061100 127061150 chr3 127613424 127613474 chr3134503235 134503285 chr3 143946141 143946191 chr3 149458833 149458883chr3 163625887 163625937 chr3 194924619 194924669 chr3 195969315195969365 chr3 196194851 196194901 chr3 197390941 197390991 chr3197391066 197391116 chr4 5659821 5659871 chr4 8674719 8674769 chr49707683 9707733 chr4 15672767 15672817 chr4 33784887 33784937 chr437953700 37953750 chr4 57625192 57625242 chr4 66323064 66323114 chr478469120 78469170 chr4 79061569 79061619 chr4 89315394 89315444 chr4110105944 110105994 chr4 115704843 115704893 chr4 132588188 132588238chr4 136007219 136007269 chr4 146385129 146385179 chr4 147206181147206231 chr4 151666715 151666765 chr4 156921015 156921065 chr4156921119 156921169 chr4 156921601 156921651 chr4 156921661 156921711chr4 162325233 162325283 chr4 172360765 172360815 chr4 173292494173292544 chr4 174159601 174159651 chr4 177261252 177261302 chr4186362152 186362202 chr4 189431979 189432029 chr5 230617 230667 chr52970627 2970677 chr5 3059054 3059104 chr5 13460833 13460883 chr514609839 14609889 chr5 18589610 18589660 chr5 23756624 23756674 chr529110961 29111011 chr5 29110665 29110715 chr5 38648614 38648664 chr543562065 43562115 chr5 51680922 51680972 chr5 55193132 55193182 chr568232572 68232622 chr5 68497399 68497449 chr5 68557784 68557834 chr5108032405 108032455 chr5 112022411 112022461 chr5 114807957 114808007chr5 119286423 119286473 chr5 119447740 119447790 chr5 126161998126162048 chr5 151732275 151732325 chr5 174954406 174954456 chr1176352926 76352976 chr6 2884781 2884831 chr6 6231265 6231315 chr1177486368 77486418 chr6 11211938 11211988 chr6 11212433 11212483 chr611212748 11212798 chr6 11219727 11219777 chr11 78032918 78032968 chr615094559 15094609 chr6 28937722 28937772 chr6 28937622 28937672 chr628938505 28938555 chr11 88994865 88994915 chr6 65387152 65387202 chr666271660 66271710 chr6 79183274 79183324 chr6 85387403 85387453 chr1192351129 92351179 chr6 109964713 109964763 chr6 110860280 110860330 chr6111363795 111363845 chr6 123138363 123138413 chr6 123279225 123279275chr6 131688049 131688099 chr6 133124888 133124938 chr6 137603072137603122 chr6 151242532 151242582 chr6 158037804 158037854 chr11101878159 101878209 chr6 164281775 164281825 chr6 166448032 166448082chr6 167888561 167888611 chr6 167888721 167888771 chr6 167888898167888948 chr6 167889392 167889442 chr6 167889576 167889626 chr6167889858 167889908 chr6 167890047 167890097 chr11 107190533 107190583chr7 2997245 2997295 chr7 7427513 7427563 chr7 7469628 7469678 chr79869259 9869309 chr7 21173104 21173154 chr7 21194663 21194713 chr722995847 22995897 chr7 38472857 38472907 chr7 39501112 39501162 chr742499293 42499343 chr7 64859931 64859981 chr11 114990576 114990626 chr768404656 68404706 chr7 72226086 72226136 chr7 77251116 77251166 chr788987751 88987801 chr7 89575707 89575757 chr7 100127855 100127905 chr7110842571 110842621 chr7 130457591 130457641 chr7 133932604 133932654chr7 137524888 137524938 chr7 144873247 144873297 chr7 149260926149260976 chr7 156137421 156137471 chr8 2339733 2339783 chr8 37997203799770 chr8 8677276 8677326 chr8 9084007 9084057 chr8 10366578 10366628chr8 19338318 19338368 chr8 22957298 22957348 chr8 22987369 22987419chr8 23037501 23037551 chr8 31396983 31397033 chr8 58165155 58165205chr8 58166699 58166749 chr8 58168596 58168646 chr8 58172838 58172888chr8 58178500 58178550 chr8 58183164 58183214 chr8 62865385 62865435chr8 107948675 107948725 chr8 114494083 114494133 chr8 115311075115311125 chr8 115541567 115541617 chr8 121579312 121579362 chr8125931758 125931808 chr8 141961852 141961902 chr8 142520013 142520063chr8 146238004 146238054 chr10 19979247 19979297 chr9 20273788 20273838chr9 21920449 21920499 chr9 21920252 21920302 chr9 35478526 35478576chr9 110490314 110490364 chr9 113882503 113882553 chr9 116459500116459550 chr9 124455240 124455290 chr12 12971558 12971608 chr1219733833 19733883 chr10 23683554 23683604 chr12 29265161 29265211 chr1230113908 30113958 chr12 30114951 30115001 chr12 39426722 39426772 chr1026727781 26727831 chr10 27000579 27000629 chr12 81555801 81555851 chr1291978491 91978541 chr12 94734691 94734741 chr10 29889872 29889922 chr1029890075 29890125 chr12 103335448 103335498 chr12 104340511 104340561chr12 117582591 117582641 chr10 32250821 32250871 chr12 120203636120203686 chr12 120596532 120596582 chr12 122506037 122506087 chr12125485678 125485728 chr12 126249765 126249815 chr12 128868938 128868988chr13 40988367 40988417 chr13 42080060 42080110 chr13 68924762 68924812chr13 75846298 75846348 chr13 78804261 78804311 chr13 86534256 86534306chr14 21187554 21187604 chr14 29698765 29698815 chr14 30700038 30700088chr14 41298867 41298917 chr14 46653531 46653581 chr14 51624752 51624802chr14 52950024 52950074 chr10 1769451 1769501 chr10 1772658 1772708chr14 59887314 59887364 chr14 69970655 69970705 chr14 72040326 72040376chr14 76091376 76091426 chr14 81104366 81104416 chr14 85611558 85611608chr10 54128381 54128431 chr14 91028550 91028600 chr14 94572110 94572160chr14 98139119 98139169 chr14 101573197 101573247 chr10 2203728 2203778chr14 103553155 103553205 chr14 104385493 104385543 chr15 2063125520631305 chr15 31257720 31257770 chr15 48820304 48820354 chr15 4882122548821275 chr10 65501634 65501684 chr15 60227200 60227250 chr15 7933985179339901 chr15 87282589 87282639 chr15 92797150 92797200 chr16 12813671281417 chr16 1281875 1281925 chr16 11364432 11364482 chr16 1365375813653808 chr16 13667863 13667913 chr16 17544138 17544188 chr16 2192585421925904 chr16 28869672 28869722 chr16 46750827 46750877 chr10 7301690173016951 chr16 59142958 59143008 chr16 62261077 62261127 chr16 6321300963213059 chr16 73791391 73791441 chr16 84775253 84775303 chr16 8602073486020784 chr17 7200812 7200862 chr17 8304225 8304275 Table 15CL. RepeatCategory MER50B chr17 40475514 40475564 chr17 58107096 58107146 chr1811893485 11893535 chr18 57784078 57784128 chr18 58260787 58260837 chr1866258530 66258580 chr10 110812158 110812208 chr10 113528085 113528135chr1 168634712 168634762 chr1 231880229 231880279 chr1 231880683231880733 chr1 231880831 231880881 chr20 50559574 50559624 chr2120996422 20996472 chr21 29486042 29486092 chr21 29486429 29486479 chr2142915781 42915831 chr22 21702098 21702148 chr22 22389230 22389280 chr2222390769 22390819 chr10 9924602 9924652 chrX 8346003 8346053 chrX15407411 15407461 chrX 86117641 86117691 chrX 96318456 96318506 chrX124980125 124980175 chrX 129601377 129601427 chrX 143048066 143048116chrX 144926632 144926682 chrX 150986787 150986837 chr11 2176869421768744 chr11 26088559 26088609 chr2 72291892 72291942 chr2 7661691676616966 chr2 121943323 121943373 chr2 129070564 129070614 chr2129071332 129071382 chr2 140648849 140648899 chr2 186562952 186563002chr2 204999799 204999849 chr3 16117645 16117695 chr3 19147900 19147950chr3 33471139 33471189 chr3 53904824 53904874 chr4 15672767 15672817chr4 115704843 115704893 chr5 230617 230667 chr5 29110961 29111011 chr529110665 29110715 chr5 38648614 38648664 chr5 43562065 43562115 chr568557784 68557834 chr5 119286423 119286473 chr5 126161998 126162048chr11 76352926 76352976 chr11 88994865 88994915 chr6 65387152 65387202chr6 79183274 79183324 chr6 110860280 110860330 chr6 123279225 123279275chr6 133124888 133124938 chr6 158037804 158037854 chr6 167888561167888611 chr6 167888721 167888771 chr6 167888898 167888948 chr6167889392 167889442 chr6 167889576 167889626 chr6 167889858 167889908chr6 167890047 167890097 chr7 7427513 7427563 chr7 68404656 68404706chr7 88987751 88987801 chr7 89575707 89575757 chr7 110842571 110842621chr7 133932604 133932654 chr7 144873247 144873297 chr7 149260926149260976 chr8 3799720 3799770 chr8 9084007 9084057 chr8 1933831819338368 chr8 22987369 22987419 chr8 107948675 107948725 chr8 115311075115311125 chr9 20273788 20273838 chr9 35478526 35478576 chr9 113882503113882553 chr9 116459500 116459550 chr10 29889872 29889922 chr1029890075 29890125 chr13 68924762 68924812 chr13 78804261 78804311 chr1386534256 86534306 chr14 41298867 41298917 chr14 52950024 52950074 chr1472040326 72040376 chr10 2203728 2203778 chr16 13653758 13653808 chr1613667863 13667913 chr16 21925854 21925904 chr16 46750827 46750877 chr1662261077 62261127 chr17 7200812 7200862 Table 15CM. Repeat CategoryMER51A chr18 13128507 13128557 chr18 13451298 13451348 chr18 1345119413451244 chr18 54644218 54644268 chr19 23641507 23641557 chr19 3363197733632027 chr19 33636370 33636420 chr19 39584959 39585009 chr19 4504130145041351 chr19 63460502 63460552 chr1 3441400 3441450 chr1 97887359788785 chr1 88825390 88825440 chr1 92979420 92979470 chr1 9508030395080353 chr1 152837627 152837677 chr1 197122950 197123000 chr1226814532 226814582 chr20 50528292 50528342 chr20 62139297 62139347chr20 62140316 62140366 chr21 37858415 37858465 chr21 42085048 42085098chr21 46129945 46129995 chr22 27454517 27454567 chr22 45504901 45504951chrX 2440265 2440315 chrX 16153038 16153088 chrX 17756325 17756375 chrX39859197 39859247 chrX 39923048 39923098 chrX 117075723 117075773 chrX117251510 117251560 chrX 117858647 117858697 chrX 129566370 129566420chr2 44472360 44472410 chr2 117121876 117121926 chr11 33165743 33165793chr2 137292398 137292448 chr3 44753207 44753257 chr3 49584281 49584331chr11 58213235 58213285 chr11 58787567 58787617 chr3 130976233 130976283chr3 186294700 186294750 chr4 3715489 3715539 chr4 42097523 42097573chr4 89833227 89833277 chr4 155265272 155265322 chr5 70967020 70967070chr5 70967098 70967148 chr5 72508920 72508970 chr5 150406150 150406200chr5 150658336 150658386 chr5 154972859 154972909 chr5 166992531166992581 chr11 76280215 76280265 chr11 77094352 77094402 chr6 2477674724776797 chr10 15280948 15280998 chr6 53272990 53273040 chr6 104939867104939917 chr6 105318610 105318660 chr11 94073642 94073692 chr7 4307365743073707 chr7 73512196 73512246 chr7 107854039 107854089 chr7 111992638111992688 chr8 31092964 31093014 chr11 125450297 125450347 chr8 8281483982814889 chr11 133253322 133253372 chr9 35478526 35478576 chr9 3745820837458258 chr9 37458995 37459045 chr9 108340671 108340721 chr9 128841920128841970 chr12 6880388 6880438 chr12 12794253 12794303 chr12 3200947132009521 chr12 32710607 32710657 chr12 50259195 50259245 chr12 8614934686149396 chr12 100959205 100959255 chr13 18493512 18493562 chr1375228906 75228956 chr14 51191313 51191363 chr14 51293738 51293788 chr1459145480 59145530 chr15 38590889 38590939 chr15 62835162 62835212 chr1567917232 67917282 chr16 1629987 1630037 chr16 3518969 3519019 chr163518839 3518889 chr16 8159255 8159305 chr16 49798300 49798350 chr1678716343 78716393 chr17 15237562 15237612 chr17 29989357 29989407 chr1731393734 31393784 chr17 31396394 31396444 chr17 31399124 31399174 chr1733905512 33905562 Table 15CN. Repeat Category MER51B chr18 4262131442621364 chr18 42621070 42621120 chr18 46175076 46175126 chr19 90460869046136 chr1 27117829 27117879 chr1 46839910 46839960 chr1 4683977646839826 chr1 52676846 52676896 chr1 80003542 80003592 chr1 8000653280006582 chr1 91139029 91139079 chr1 152493527 152493577 chr1 163711434163711484 chr1 207821617 207821667 chr1 239696896 239696946 chr10133256240 133256290 chr10 133261722 133261772 chr20 36274397 36274447chr10 134660820 134660870 chr21 45869408 45869458 chr21 4612994546129995 chrX 75974047 75974097 chrX 109550892 109550942 chrX 118910669118910719 chrX 118916368 118916418 chrX 121653168 121653218 chr2137292398 137292448 chr2 196504924 196504974 chr2 237879687 237879737chr11 57168685 57168735 chr11 58787567 58787617 chr3 122994234 122994284chr3 134835210 134835260 chr3 170852608 170852658 chr10 1292371212923762 chr4 123132 123182 chr4 122867 122917 chr4 24394633 24394683chr4 25343454 25343504 chr4 84513306 84513356 chr4 115934383 115934433chr4 140733946 140733996 chr4 140735296 140735346 chr4 140737199140737249 chr4 140739007 140739057 chr4 140740735 140740785 chr4187712639 187712689 chr4 187712729 187712779 chr5 33711979 33712029 chr543227812 43227862 chr5 43230241 43230291 chr11 70901543 70901593 chr5150650151 150650201 chr6 39767599 39767649 chr6 42965775 42965825 chr642967989 42968039 chr6 42968703 42968753 chr7 1356073 1356123 chr747916601 47916651 chr7 70826814 70826864 chr7 80790080 80790130 chr7105534829 105534879 chr7 151800784 151800834 chr7 152043172 152043222chr8 26993015 26993065 chr8 101781290 101781340 chr8 121503949 121503999chr9 134945018 134945068 chr9 135017098 135017148 chr9 135017151135017201 chr10 22571035 22571085 chr12 61140321 61140371 chr13 1812895918129009 chr13 18130048 18130098 chr13 67555939 67555989 chr14 2567983925679889 chr14 32901443 32901493 chr14 45041736 45041786 chr14 4504548445045534 chr14 101703348 101703398 chr15 39153821 39153871 chr1570692488 70692538 chr10 3048073 3048123 chr16 10826739 10826789 chr1646464711 46464761 chr16 46464632 46464682 chr16 46465470 46465520 chr1646634350 46634400 chr10 73088875 73088925 chr16 87598236 87598286 Table15CO. Repeat Category MER57A-int chr17 71650885 71650935 chr10 8905468889054738 chr18 51633492 51633542 chr18 51633214 51633264 chr19 1979405719794107 chr19 19832922 19832972 chr19 20447698 20447748 chr19 2057155920571609 chr19 21985933 21985983 chr19 22190440 22190490 chr19 2280298922803039 chr19 23087435 23087485 chr19 23086715 23086765 chr19 2337030023370350 chr19 23372156 23372206 chr19 23764904 23764954 chr19 4777716947777219 chr19 47777386 47777436 chr19 47778183 47778233 chr19 4813362748133677 chr19 48258991 48259041 chr19 48261399 48261449 chr10 107096851107096901 chr19 50570168 50570218 chr1 77060879 77060929 chr1 8152834081528390 chr1 150913487 150913537 chr1 158114298 158114348 chr1173115742 173115792 chr1 179933430 179933480 chr1 202276010 202276060chr1 210268275 210268325 chr1 225800182 225800232 chr1 225802953225803003 chr20 24195235 24195285 chr20 30581384 30581434 chr20 3345127833451328 chr20 42803404 42803454 chr20 47180930 47180980 chr10 134829903134829953 chr21 32852866 32852916 chr22 15704972 15705022 chr11 18830691883119 chr11 1887412 1887462 chr11 1889686 1889736 chrX 2613542026135470 chrX 88202876 88202926 chrX 89435851 89435901 chrX 125771444125771494 chrY 3316496 3316546 chr2 69655094 69655144 chr2 8569392885693978 chr2 207041579 207041629 chr2 219857800 219857850 chr2236491263 236491313 chr3 33469000 33469050 chr3 126459975 126460025 chr3130413623 130413673 chr3 151890279 151890329 chr3 164275494 164275544chr3 169600014 169600064 chr4 72182187 72182237 chr4 124175490 124175540chr5 37805368 37805418 chr5 102458904 102458954 chr5 110297575 110297625chr5 110304838 110304888 chr5 152137696 152137746 chr5 171704461171704511 chr5 171706637 171706687 chr5 174965181 174965231 chr5174966747 174966797 chr5 174975174 174975224 chr5 175786623 175786673chr5 175787006 175787056 chr6 33152778 33152828 chr6 85004326 85004376chr6 132832115 132832165 chr6 137679565 137679615 chr6 142403775142403825 chr6 145498033 145498083 chr6 153761283 153761333 chr713549564 13549614 chr7 32722959 32723009 chr7 32953863 32953913 chr732955588 32955638 chr7 55442030 55442080 chr7 64095746 64095796 chr764243980 64244030 chr7 96559666 96559716 chr7 96561265 96561315 chr7103231387 103231437 chr7 158525233 158525283 chr8 18070627 18070677chr11 124965214 124965264 chr8 66835944 66835994 chr8 74879262 74879312chr8 103954219 103954269 chr8 125328895 125328945 chr8 125332371125332421 chr8 144870176 144870226 chr9 72531694 72531744 chr9 7253297472533024 chr9 129840359 129840409 chr9 129841253 129841303 chr10 260703260753 chr12 25996105 25996155 chr12 29569903 29569953 chr12 2956972429569774 chr12 34244293 34244343 chr13 36798213 36798263 chr10 4215105942151109 chr10 46447419 46447469 chr14 30226176 30226226 chr14 3668199136682041 chr14 36683226 36683276 chr10 48936967 48937017 chr14 6933478869334838 chr14 83370269 83370319 chr14 85575100 85575150 chr15 2388836523888415 chr15 91039462 91039512 chr16 2780566 2780616 chr16 2796532827965378 chr16 74373896 74373946 chr17 14516084 14516134 chr17 1451871714518767 Table 15CP. Repeat Category MER6 chr17 38344004 38344054 chr1081859646 81859696 chr10 81859236 81859286 chr10 81987068 81987118 chr1081996443 81996493 chr10 81996779 81996829 chr10 81996902 81996952 chr1742159421 42159471 chr17 42338242 42338292 chr17 42610400 42610450 chr1742806831 42806881 chr10 82378155 82378205 chr17 44792287 44792337 chr1746041043 46041093 chr17 46294369 46294419 chr17 47504094 47504144 chr1747945390 47945440 chr17 48146243 48146293 chr10 83919766 83919816 chr1748326788 48326838 chr17 48606392 48606442 chr17 49841124 49841174 chr1750076663 50076713 chr17 50076545 50076595 chr17 51379827 51379877 chr1751474424 51474474 chr17 53982663 53982713 chr17 55371841 55371891 chr1755383852 55383902 chr10 85805403 85805453 chr10 85805945 85805995 chr1085949723 85949773 chr17 59595918 59595968 chr17 65148923 65148973 chr1771139590 71139640 chr17 71270125 71270175 chr17 72848106 72848156 chr1088647234 88647284 chr17 73801340 73801390 chr17 74953388 74953438 chr1775176876 75176926 chr17 75380250 75380300 chr17 75886905 75886955 chr1775888082 75888132 chr17 76150864 76150914 chr17 76385061 76385111 chr1777036236 77036286 chr17 77036010 77036060 chr17 77209288 77209338 chr1777265523 77265573 chr17 77982432 77982482 chr17 78525870 78525920 chr1778527383 78527433 chr17 78847153 78847203 chr17 78912489 78912539 chr1778912378 78912428 chr10 91502212 91502262 chr17 79277553 79277603 chr1779459896 79459946 chr17 79617097 79617147 chr17 79912643 79912693 chr1092494429 92494479 chr17 80633910 80633960 chr17 80671667 80671717 chr104545080 4545130 chr18 3647883 3647933 chr18 4891166 4891216 chr186275226 6275276 chr18 8659822 8659872 chr18 8843767 8843817 chr189425093 9425143 chr18 10916207 10916257 chr18 12397116 12397166 chr1813561912 13561962 chr10 94757308 94757358 chr18 15326824 15326874 chr1818708053 18708103 chr18 24452956 24453006 chr18 25891941 25891991 chr1826200976 26201026 chr18 26823808 26823858 chr18 27385061 27385111 chr1827660595 27660645 chr18 27998944 27998994 chr18 29395873 29395923 chr1835631797 35631847 chr18 41932712 41932762 chr18 42621314 42621364 chr1842621070 42621120 chr18 42958118 42958168 chr10 5129359 5129409 chr1846554807 46554857 chr18 50165618 50165668 chr18 54338110 54338160 chr1854819342 54819392 chr18 55125069 55125119 chr18 55339400 55339450 chr1856314587 56314637 chr18 56665314 56665364 chr18 58471019 58471069 chr1858690757 58690807 chr18 58938483 58938533 chr18 59367070 59367120 chr1860142566 60142616 chr18 62321171 62321221 chr18 63005517 63005567 chr1864670156 64670206 chr18 65443448 65443498 chr18 66772560 66772610 chr1867314825 67314875 chr18 67600759 67600809 chr18 68508443 68508493 chr1868510276 68510326 chr18 69857096 69857146 chr18 70206558 70206608 chr1872581730 72581780 chr18 72587569 72587619 chr18 72895069 72895119 chr1872894895 72894945 chr18 73759407 73759457 chr18 73783026 73783076 chr1874579864 74579914 chr18 75775885 75775935 chr18 75847633 75847683 chr1875847987 75848037 chr18 76004501 76004551 chr18 76005154 76005204 chr19330893 330943 chr19 438082 438132 chr10 99838254 99838304 chr10 9983818299838232 chr10 100049969 100050019 chr19 2075531 2075581 chr19 27990912799141 chr19 2896558 2896608 chr19 2918744 2918794 chr19 31500923150142 chr19 4085549 4085599 chr19 4209367 4209417 chr19 45959314595981 chr19 4704468 4704518 chr19 4738227 4738277 chr19 57273195727369 chr19 6756116 6756166 chr19 7079091 7079141 chr19 71355467135596 chr19 7721357 7721407 chr19 7722794 7722844 chr19 79178457917895 chr19 8969662 8969712 chr19 9030711 9030761 chr19 90324269032476 chr19 9135767 9135817 chr19 11748558 11748608 chr19 1191379711913847 chr19 12045258 12045308 chr19 12237854 12237904 chr19 1363032813630378 chr19 13653674 13653724 chr19 14292747 14292797 chr10 102974097102974147 chr19 15033996 15034046 chr19 16580710 16580760 chr19 1658118316581233 chr19 18036599 18036649 chr19 18156781 18156831 chr19 2005735220057402 chr19 20262196 20262246 chr19 20352774 20352824 chr19 2227232922272379 chr19 22399725 22399775 chr19 22559892 22559942 chr19 2261672422616774 chr19 37744604 37744654 chr19 37756027 37756077 chr19 3821302138213071 chr19 39024517 39024567 chr19 39324871 39324921 chr19 3941955739419607 chr19 39801207 39801257 chr19 39807847 39807897 chr19 4038487040384920 chr19 42870509 42870559 chr19 42871851 42871901 chr19 4287289442872944 chr19 42878521 42878571 chr19 43752065 43752115 chr19 4390930843909358 chr19 44206013 44206063 chr19 44214716 44214766 chr19 4421512644215176 chr19 44216030 44216080 chr19 44216311 44216361 chr19 4421677944216829 chr19 44216859 44216909 chr19 44220917 44220967 chr19 4422637944226429 chr19 44229185 44229235 chr19 44312811 44312861 chr19 4531327445313324 chr19 45365521 45365571 chr19 45365588 45365638 chr19 4692457046924620 chr19 46925002 46925052 chr19 46925274 46925324 chr19 4692555446925604 chr19 46925864 46925914 chr19 46964552 46964602 chr19 4696497846965028 chr19 46965165 46965215 chr19 46965363 46965413 chr19 4781353047813580 chr19 47866984 47867034 chr10 106643402 106643452 chr1948189349 48189399 chr19 48540615 48540665 chr19 48540321 48540371 chr1948654504 48654554 chr19 49386611 49386661 chr19 50148168 50148218 chr1950363451 50363501 chr19 50363638 50363688 chr19 50507087 50507137 chr1950507255 50507305 chr10 109025149 109025199 chr19 51679736 51679786chr19 51680044 51680094 chr19 51680181 51680231 chr19 52459396 52459446chr19 52459695 52459745 chr19 52485290 52485340 chr19 52540881 52540931chr19 53450073 53450123 chr19 54499741 54499791 chr19 55191494 55191544chr19 55636124 55636174 chr19 56094980 56095030 chr19 56503997 56504047chr19 56549951 56550001 chr19 56556545 56556595 chr19 56672956 56673006chr19 57834593 57834643 chr19 57921962 57922012 chr19 57933409 57933459chr19 58054452 58054502 chr19 58139364 58139414 chr19 58192274 58192324chr19 58551674 58551724 chr19 59022879 59022929 chr19 59520855 59520905chr19 59521103 59521153 chr19 59791392 59791442 chr10 6059521 6059571chr19 60145473 60145523 chr10 114275315 114275365 chr10 114275170114275220 chr19 60931278 60931328 chr19 61172002 61172052 chr19 6136908761369137 chr19 61673912 61673962 chr19 61673765 61673815 chr19 6220691562206965 chr19 63624475 63624525 chr1 1219130 1219180 chr1 12256291225679 chr1 1463120 1463170 chr1 1959049 1959099 chr1 2222080 2222130chr10 115289131 115289181 chr1 3958458 3958508 chr1 4390316 4390366chr10 115879925 115879975 chr1 8853924 8853974 chr1 8886972 8887022 chr19179315 9179365 chr10 117046557 117046607 chr1 9297577 9297627 chr110696981 10697031 chr1 11042462 11042512 chr1 11395225 11395275 chr113900746 13900796 chr1 14530795 14530845 chr1 17395065 17395115 chr119584604 19584654 chr1 19693410 19693460 chr1 21945039 21945089 chr10119668846 119668896 chr1 22727204 22727254 chr1 23062260 23062310 chr124033094 24033144 chr1 24064272 24064322 chr1 26953633 26953683 chr130150643 30150693 chr1 32282590 32282640 chr1 32605274 32605324 chr136098518 36098568 chr1 37416193 37416243 chr1 39126439 39126489 chr139601783 39601833 chr1 39798956 39799006 chr1 39879966 39880016 chr143212208 43212258 chr1 43248074 43248124 chr1 43933310 43933360 chr143937538 43937588 chr1 45456542 45456592 chr1 45776159 45776209 chr146160842 46160892 chr1 46858225 46858275 chr1 49623259 49623309 chr150188781 50188831 chr1 52065869 52065919 chr1 57666817 57666867 chr161572991 61573041 chr1 62160833 62160883 chr1 62563329 62563379 chr162868674 62868724 chr1 63031228 63031278 chr1 66911631 66911681 chr106581662 6581712 chr1 69048209 69048259 chr10 124286273 124286323 chr175928156 75928206 chr1 79318898 79318948 chr1 81768927 81768977 chr181769070 81769120 chr1 81769354 81769404 chr1 82665820 82665870 chr186088966 86089016 chr1 86089283 86089333 chr1 89101819 89101869 chr190821623 90821673 chr1 101254657 101254707 chr1 101549591 101549641 chr1106534127 106534177 chr1 107441342 107441392 chr10 126161462 126161512chr1 113035091 113035141 chr1 113615663 113615713 chr1 114743350114743400 chr1 115767146 115767196 chr1 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81145381 chr16 83888882 83888932 chr16 83888801 83888851 chr1684058635 84058685 chr16 84298435 84298485 chr16 84544601 84544651 chr103319173 3319223 chr16 85707442 85707492 chr16 86205946 86205996 chr1686435063 86435113 chr16 88082341 88082391 chr16 88376360 88376410 chr1688661183 88661233 chr16 89019672 89019722 chr16 89108789 89108839 chr1689859686 89859736 chr17 1690348 1690398 chr17 3139463 3139513 chr173634038 3634088 chr17 4632158 4632208 chr17 5019479 5019529 chr175591913 5591963 chr17 6528819 6528869 chr17 6529802 6529852 chr176812177 6812227 chr17 7045807 7045857 chr17 7082884 7082934 chr177248036 7248086 chr17 7556256 7556306 chr17 7631704 7631754 chr179821572 9821622 chr17 9842486 9842536 chr17 9950959 9951009 chr1710074695 10074745 chr17 10238641 10238691 chr17 14852141 14852191 chr1717654261 17654311 chr17 19801094 19801144 chr10 80053063 80053113 chr1728120190 28120240 chr17 28258819 28258869 chr17 28278019 28278069 chr1730393270 30393320 chr17 36831448 36831498 chr10 81563691 81563741 Table15CQ. Repeat Category MER63A chr17 38344004 38344054 chr18 2799894427998994 chr18 54338110 54338160 chr18 58938483 58938533 chr18 5936707059367120 chr18 62321171 62321221 chr19 438082 438132 chr19 57273195727369 chr19 14292747 14292797 chr19 40384870 40384920 chr19 6014547360145523 chr19 61673912 61673962 chr19 61673765 61673815 chr1 1390074613900796 chr1 17395065 17395115 chr1 21945039 21945089 chr1 2403309424033144 chr1 39601783 39601833 chr10 124286273 124286323 chr1 9082162390821673 chr1 113615663 113615713 chr1 147965385 147965435 chr1154089424 154089474 chr1 201953707 201953757 chr1 201953594 201953644chr1 208377402 208377452 chr1 217611296 217611346 chr1 231333978231334028 chr20 1639037 1639087 chr20 4794544 4794594 chr20 1925646819256518 chr20 25016578 25016628 chr21 31772150 31772200 chr21 4037517340375223 chr22 23950631 23950681 chr11 2006284 2006334 chr22 4189092741890977 chrX 11555492 11555542 chrX 38684803 38684853 chrX 9453970494539754 chrX 121777001 121777051 chr2 3145169 3145219 chr2 87082838708333 chr2 39593484 39593534 chr2 61902549 61902599 chr2 6410861364108663 chr11 28567205 28567255 chr2 203095986 203096036 chr2 206690687206690737 chr2 207618146 207618196 chr2 230717019 230717069 chr2240638557 240638607 chr3 33972706 33972756 chr3 35786197 35786247 chr335786085 35786135 chr3 53172979 53173029 chr3 62349113 62349163 chr365768491 65768541 chr3 114617897 114617947 chr3 128126644 128126694 chr3133026334 133026384 chr3 190263915 190263965 chr3 191615997 191616047chr4 5629895 5629945 chr4 6429501 6429551 chr4 46426251 46426301 chr477296608 77296658 chr4 110762298 110762348 chr4 158890212 158890262 chr4167213535 167213585 chr4 188362110 188362160 chr4 188362485 188362535chr4 188362567 188362617 chr4 191221781 191221831 chr11 6959188169591931 chr11 69591678 69591728 chr5 53204858 53204908 chr5 5820780258207852 chr5 80159780 80159830 chr5 157928299 157928349 chr5 157978767157978817 chr5 172017491 172017541 chr5 174009991 174010041 chr5180600261 180600311 chr6 37008654 37008704 chr6 42178912 42178962 chr1194557072 94557122 chr11 94857374 94857424 chr6 123110279 123110329 chr74279874 4279924 chr11 111790318 111790368 chr7 67220930 67220980 chr7120032332 120032382 chr7 124669591 124669641 chr7 157682380 157682430chr8 21771256 21771306 chr8 139246315 139246365 chr9 3891195 3891245chr9 3891098 3891148 chr9 68289256 68289306 chr9 93525460 93525510 chr9130013737 130013787 chr9 131908284 131908334 chr9 135389171 135389221chr10 21769230 21769280 chr12 6080881 6080931 chr12 6822395 6822445chr12 25861147 25861197 chr12 49631606 49631656 chr10 29300672 29300722chr12 103917345 103917395 chr12 119820254 119820304 chr12 128390825128390875 chr13 22078920 22078970 chr10 36624838 36624888 chr13 2994974729949797 chr14 22748871 22748921 chr10 50093323 50093373 chr14 6143504861435098 chr10 61977266 61977316 chr15 32273533 32273583 chr15 3980419639804246 chr15 49992843 49992893 chr16 5794972 5795022 chr16 2527569625275746 chr16 84058635 84058685 chr17 9842486 9842536 Table 15CR.Repeat Category MER66C chr17 78847153 78847203 chr10 4545080 4545130chr19 7721357 7721407 chr19 7722794 7722844 chr19 18156781 18156831chr19 44229185 44229235 chr19 56094980 56095030 chr1 82665820 82665870chr1 173925499 173925549 chr1 206210941 206210991 chr1 228456118228456168 chr1 241661772 241661822 chr20 2422840 2422890 chr20 1788619617886246 chr20 32753740 32753790 chrX 51019934 51019984 chr2 1323430113234351 chr2 76646860 76646910 chr2 97206283 97206333 chr2 188021552188021602 chr11 46409574 46409624 chr3 15394903 15394953 chr3 5275397052754020 chr3 130110962 130111012 chr3 147960623 147960673 chr4 55914485591498 chr4 5591361 5591411 chr4 46782153 46782203 chr4 7216298772163037 chr4 185333536 185333586 chr4 189808416 189808466 chr5 14285711428621 chr11 105728036 105728086 chr7 55418979 55419029 chr7 7295453872954588 chr7 147615956 147616006 chr8 34494590 34494640 chr8 4008117440081224 chr9 19108028 19108078 chr9 26351897 26351947 chr11 133253322133253372 chr11 133252830 133252880 chr9 67879966 67880016 chr9 6788233967882389 chr10 23673113 23673163 chr12 47824452 47824502 chr13 4794544747945497 chr13 48199533 48199583 chr13 99044495 99044545 chr16 6359717863597228 chr16 89019672 89019722 chr17 5019479 5019529 chr17 65288196528869 chr17 7248036 7248086 Table 15CS. Repeat Category MER67A chr1755383852 55383902 chr18 42958118 42958168 chr1 239052461 239052511 chr1245891792 245891842 chr22 18306254 18306304 chr22 18308023 18308073chr22 18313807 18313857 chr22 34118405 34118455 chr22 46581440 46581490chr22 48519005 48519055 chr2 61079326 61079376 chr4 43882990 43883040chr4 44591443 44591493 chr4 69226257 69226307 chr4 77304481 77304531chr4 166532817 166532867 chr4 176200658 176200708 chr4 188984139188984189 chr5 105996596 105996646 chr5 178379857 178379907 chr626425471 26425521 chr6 27202998 27203048 chr6 37946584 37946634 chr74748760 4748810 chr7 20088989 20089039 chr7 51835806 51835856 chr827770505 27770555 chr8 59625641 59625691 chr9 34147287 34147337 chr9113598091 113598141 chr13 18187302 18187352 chr13 80882686 80882736chr14 43582701 43582751 chr10 49660196 49660246 chr16 17329171 17329221chr10 73135375 73135425 chr16 62533813 62533863 chr16 62535158 62535208chr17 14852141 14852191 Table 15CT. Repeat Category MER67D chr1750076663 50076713 chr17 50076545 50076595 chr18 26200976 26201026 chr1856314587 56314637 chr18 56665314 56665364 chr18 65443448 65443498 chr1869857096 69857146 chr18 72895069 72895119 chr18 72894895 72894945 chr10109025149 109025199 chr1 191824637 191824687 chr1 192481463 192481513chr20 42661734 42661784 chr21 46405158 46405208 chr22 44216198 44216248chrX 28582994 28583044 chr2 721783 721833 chr2 52641697 52641747 chr294875133 94875183 chr2 129760002 129760052 chr2 130830586 130830636 chr2132332374 132332424 chr2 187397091 187397141 chr11 39455224 39455274chr4 43458321 43458371 chr4 133498126 133498176 chr4 135529961 135530011chr4 162228125 162228175 chr4 163496714 163496764 chr4 171947817171947867 chr5 25430145 25430195 chr5 28748974 28749024 chr5 2934107729341127 chr5 29342489 29342539 chr6 116186093 116186143 chr6 142031461142031511 chr11 105740918 105740968 chr7 66893714 66893764 chr8 13000771300127 chr8 87038216 87038266 chr8 137401134 137401184 chr9 1244978712449837 chr9 120674529 120674579 chr12 40613466 40613516 chr12126782831 126782881 chr13 62898016 62898066 chr13 80970219 80970269chr13 85093609 85093659 chr13 86267888 86267938 Table 15CU. RepeatCategory MER6A chr17 55371841 55371891 chr18 18708053 18708103 chr1858690757 58690807 chr19 50363451 50363501 chr19 50363638 50363688 chr1185754121 185754171 chr1 187276631 187276681 chr1 197896466 197896516chr1 228550874 228550924 chr20 6039693 6039743 chr21 16298966 16299016chr21 37224689 37224739 chr21 41936038 41936088 chr22 30222092 30222142chr10 9924602 9924652 chr11 3994157 3994207 chrX 24011092 24011142 chrX24013248 24013298 chrX 30468831 30468881 chrX 33851654 33851704 chr29534966 9535016 chr2 54881521 54881571 chr2 65267889 65267939 chr286160451 86160501 chr2 97944141 97944191 chr2 107773049 107773099 chr2107772966 107773016 chr2 127420107 127420157 chr2 132110033 132110083chr2 197701075 197701125 chr2 199045946 199045996 chr2 236793626236793676 chr3 5078949 5078999 chr3 5079989 5080039 chr3 1352867113528721 chr3 19251241 19251291 chr11 55228251 55228301 chr3 7046282270462872 chr3 85438381 85438431 chr3 175744173 175744223 chr3 195486668195486718 chr4 6083158 6083208 chr4 38617257 38617307 chr4 9859157798591627 chr4 182182875 182182925 chr4 185170015 185170065 chr4185171342 185171392 chr4 185171569 185171619 chr5 698725 698775 chr53875646 3875696 chr5 52894591 52894641 chr5 55743123 55743173 chr610913493 10913543 chr6 20553687 20553737 chr6 66948363 66948413 chr6106398279 106398329 chr6 136892550 136892600 chr6 159382256 159382306chr6 167038839 167038889 chr6 167039107 167039157 chr6 167039337167039387 chr6 168410745 168410795 chr7 50868184 50868234 chr7 127787213127787263 chr7 143748226 143748276 chr8 142130704 142130754 chr11130353664 130353714 chr9 3915610 3915660 chr9 9701044 9701094 chr932909794 32909844 chr12 7148199 7148249 chr12 68865794 68865844 chr12106812813 106812863 chr14 53514748 53514798 chr14 53515273 53515323chr14 79558200 79558250 chr14 89992937 89992987 chr15 37753331 37753381chr15 40946542 40946592 chr15 68798226 68798276 chr15 99846757 99846807chr16 24500904 24500954 chr16 54790634 54790684 chr17 6812177 6812227chr17 9821572 9821622 Table 15CV. Repeat Category MER70A chr17 4902835249028402 chr17 49029549 49029599 chr19 2844874 2844924 chr19 3620606336206113 chr1 214702420 214702470 chr1 244143609 244143659 chr20 41782794178329 chr20 41029425 41029475 chr21 22190325 22190375 chr21 2239282722392877 chr21 22392663 22392713 chrX 15167186 15167236 chr2 6587819865878248 chr2 89187161 89187211 chr2 90025987 90026037 chr2 140817822140817872 chr2 211944927 211944977 chr2 232490643 232490693 chr464886141 64886191 chr4 117912241 117912291 chr5 36079493 36079543 chr1170188073 70188123 chr5 111643930 111643980 chr6 2748663 2748713 chr62750521 2750571 chr11 88029680 88029730 chr6 78646575 78646625 chr6156712221 156712271 chr11 103636850 103636900 chr7 125278747 125278797chr9 95884785 95884835 chr14 20441597 20441647 chr14 22393930 22393980chr14 22393844 22393894 chr14 72066958 72067008 chr10 65702323 65702373chr16 18259831 18259881 chr10 3305135 3305185 chr10 3304915 3304965Table 15CW. Repeat Category MER91C chr17 79249366 79249416 chr1827283995 27284045 chr10 102278766 102278816 chr19 10423266 10423316chr19 14546057 14546107 chr1 40709068 40709118 chr1 40708963 40709013chr1 84418440 84418490 chr1 114306751 114306801 chr1 218042807 218042857chr20 49748527 49748577 chr21 26224437 26224487 chr21 41440257 41440307chr22 15922229 15922279 chr22 44257847 44257897 chrX 39189265 39189315chrX 128819807 128819857 chr2 234021660 234021710 chr3 64717860 64717910chr3 161350757 161350807 chr4 47647420 47647470 chr11 66678301 66678351chr4 148700551 148700601 chr5 75094719 75094769 chr5 75094792 75094842chr6 90326547 90326597 chr11 96096607 96096657 chr6 131090917 131090967chr6 167338450 167338500 chr6 167338363 167338413 chr11 118942385118942435 chr11 119877086 119877136 chr9 77759196 77759246 chr9123956146 123956196 chr9 127839512 127839562 chr12 88291980 88292030chr12 93060962 93061012 chr14 89034619 89034669 chr14 89034471 89034521chr14 91414691 91414741 chr15 72117868 72117918 chr15 73334369 73334419chr16 23296035 23296085 chr16 84369434 84369484 Table 15CX. RepeatCategory MER92B chr18 60093475 60093525 chr19 11573890 11573940 chr1912261802 12261852 chr19 12331811 12331861 chr19 12518151 12518201 chr1919874828 19874878 chr19 19875997 19876047 chr19 20141234 20141284 chr1920142444 20142494 chr19 20397413 20397463 chr19 20999109 20999159 chr1921120161 21120211 chr19 23767442 23767492 chr19 24009324 24009374 chr1958196749 58196799 chr1 3685744 3685794 chr1 244186563 244186613 chr1244392331 244392381 chr20 23180294 23180344 chr20 23284166 23284216chr20 36262386 36262436 chr20 38227723 38227773 chr20 60213963 60214013chr21 30166800 30166850 chr21 38252030 38252080 chr21 41843126 41843176chr21 43255981 43256031 chr21 43381929 43381979 chr21 43509824 43509874chr10 601716 601766 chrX 141389174 141389224 chrX 141389603 141389653chrX 150782676 150782726 chrY 27454781 27454831 chr2 627506 627556 chr224137717 24137767 chr2 24137533 24137583 chr11 24703597 24703647 chr295550831 95550881 chr2 96158888 96158938 chr2 127802962 127803012 chr2198432701 198432751 chr2 199673167 199673217 chr2 230690606 230690656chr3 11287847 11287897 chr3 149325158 149325208 chr3 181791360 181791410chr4 4404190 4404240 chr4 87847349 87847399 chr4 118913897 118913947chr6 80475146 80475196 chr6 154120105 154120155 chr6 164999271 164999321chr11 107269280 107269330 chr7 2995204 2995254 chr7 34434499 34434549chr7 63340085 63340135 chr7 64254638 64254688 chr7 98047417 98047467chr8 32825100 32825150 chr8 143270260 143270310 chr8 143270046 143270096chr9 74527285 74527335 chr12 31673502 31673552 chr12 127831449 127831499chr13 53762636 53762686 chr13 101454108 101454158 chr13 104664019104664069 chr14 102175034 102175084 chr14 102761115 102761165 chr1567656495 67656545 chr16 87637388 87637438 Table 15CY. Repeat CategoryMLT1A chr10 81611942 81611992 chr10 81975981 81976031 chr17 4238918142389231 chr10 82047624 82047674 chr17 44792287 44792337 chr17 4565204845652098 chr10 83225068 83225118 chr17 46976620 46976670 chr17 4782255747822607 chr17 49571045 49571095 chr17 53252158 53252208 chr17 5558114255581192 chr17 60775221 60775271 chr17 61210321 61210371 chr17 6294945762949507 chr17 64026522 64026572 chr17 66826329 66826379 chr17 6695437266954422 chr17 68401794 68401844 chr17 70642640 70642690 chr17 7173604271736092 chr17 72359287 72359337 chr17 72531357 72531407 chr17 7322344173223491 chr17 73232506 73232556 chr10 88661731 88661781 chr10 8875770388757753 chr17 75363032 75363082 chr17 75443452 75443502 chr17 7561351275613562 chr17 76177819 76177869 chr17 76889972 76890022 chr17 7690322076903270 chr17 77230554 77230604 chr17 77230477 77230527 chr17 7857928078579330 chr17 79310647 79310697 chr17 79652646 79652696 chr10 9332065993320709 chr17 81683706 81683756 chr18 2954315 2954365 chr18 35191653519215 chr18 3518978 3519028 chr18 3608626 3608676 chr18 45591484559198 chr18 4959385 4959435 chr18 5017849 5017899 chr18 50380265038076 chr18 7128794 7128844 chr18 7341710 7341760 chr18 73818397381889 chr18 8716666 8716716 chr18 10647798 10647848 chr10 9472254694722596 chr18 13833454 13833504 chr18 13935237 13935287 chr18 1753971517539765 chr18 17913844 17913894 chr18 18628985 18629035 chr18 1901670619016756 chr18 19236242 19236292 chr18 19423005 19423055 chr18 2067155120671601 chr18 21836914 21836964 chr10 95605602 95605652 chr18 2247486122474911 chr10 95760596 95760646 chr18 25074663 25074713 chr10 9672440096724450 chr18 38348176 38348226 chr18 45244783 45244833 chr18 4649357646493626 chr18 46493517 46493567 chr18 47518863 47518913 chr18 4892375348923803 chr18 49828173 49828223 chr18 51774084 51774134 chr18 5345634153456391 chr18 57656031 57656081 chr10 98244194 98244244 chr18 6040943960409489 chr18 63126120 63126170 chr18 63723225 63723275 chr18 6469484664694896 chr18 65801419 65801469 chr18 66218240 66218290 chr18 6716744667167496 chr18 67364975 67365025 chr18 67364821 67364871 chr18 6756497967565029 chr18 68015471 68015521 chr18 68594111 68594161 chr18 6879485968794909 chr18 69892343 69892393 chr18 70215324 70215374 chr18 7061503270615082 chr18 71939462 71939512 chr18 74012476 74012526 chr10 9899454898994598 chr18 74786938 74786988 chr18 74808282 74808332 chr19 310891310941 chr19 2422245 2422295 chr19 3056906 3056956 chr19 5858131 5858181chr19 6385257 6385307 chr10 102054584 102054634 chr19 8759702 8759752chr19 10512264 10512314 chr19 11687350 11687400 chr19 11688645 11688695chr19 11726812 11726862 chr19 12254092 12254142 chr19 12533347 12533397chr19 13098307 13098357 chr19 13275759 13275809 chr19 13535918 13535968chr19 13606603 13606653 chr19 14420236 14420286 chr19 16646692 16646742chr19 16647855 16647905 chr19 16758682 16758732 chr19 16771851 16771901chr19 16771760 16771810 chr19 16941728 16941778 chr10 103319368103319418 chr10 103597586 103597636 chr19 18790945 18790995 chr1934809321 34809371 chr19 35909737 35909787 chr19 36311614 36311664 chr1936311413 36311463 chr19 37617490 37617540 chr19 38965314 38965364 chr1945365521 45365571 chr19 45365588 45365638 chr19 45876484 45876534 chr1949121414 49121464 chr19 49121314 49121364 chr19 49178403 49178453 chr10107792814 107792864 chr19 49361007 49361057 chr19 49788468 49788518chr10 108184472 108184522 chr10 108303197 108303247 chr19 5136245451362504 chr10 110043280 110043330 chr19 52149177 52149227 chr1952148809 52148859 chr19 52481083 52481133 chr19 53209375 53209425 chr1953434483 53434533 chr10 112161847 112161897 chr19 55268566 55268616chr19 56403657 56403707 chr19 56930240 56930290 chr19 57357731 57357781chr19 57678883 57678933 chr19 57904690 57904740 chr19 58129969 58130019chr19 61281807 61281857 chr19 61348792 61348842 chr19 61642757 61642807chr19 61880909 61880959 chr19 62143366 62143416 chr19 62176096 62176146chr19 62191428 62191478 chr1 2422896 2422946 chr1 3239901 3239951 chr13508591 3508641 chr1 4861387 4861437 chr1 5617136 5617186 chr1 69889986989048 chr1 7026200 7026250 chr10 116568218 116568268 chr1 86118498611899 chr1 11676008 11676058 chr1 13170889 13170939 chr10 118119298118119348 chr1 13329594 13329644 chr1 13498819 13498869 chr1 1350943413509484 chr1 13509267 13509317 chr1 17194457 17194507 chr1 1858237618582426 chr1 21199715 21199765 chr1 22803523 22803573 chr1 2345748723457537 chr10 120277329 120277379 chr1 26264385 26264435 chr10 62966296296679 chr1 27573683 27573733 chr1 31822718 31822768 chr10 120915467120915517 chr1 35177854 35177904 chr1 35705258 35705308 chr10 121029097121029147 chr10 121188378 121188428 chr1 38623270 38623320 chr1 3991647539916525 chr1 42245641 42245691 chr1 42598225 42598275 chr1 4290632442906374 chr1 45126460 45126510 chr1 50552740 50552790 chr1 5240114252401192 chr1 53240211 53240261 chr1 54347852 54347902 chr1 5577166555771715 chr1 60438978 60439028 chr1 63061742 63061792 chr1 6317240863172458 chr1 63172931 63172981 chr1 64956952 64957002 chr1 6512522365125273 chr1 66943454 66943504 chr1 67020448 67020498 chr1 6999958669999636 chr1 78659185 78659235 chr1 79154137 79154187 chr1 7920861279208662 chr1 79237605 79237655 chr1 81416608 81416658 chr1 8148464181484691 chr1 82025148 82025198 chr1 82298900 82298950 chr1 8326835083268400 chr1 83577899 83577949 chr1 87979260 87979310 chr1 8949148789491537 chr1 89490800 89490850 chr1 91971378 91971428 chr1 9276558792765637 chr1 92923914 92923964 chr1 92923775 92923825 chr1 9336032393360373 chr1 93360776 93360826 chr1 94948623 94948673 chr1 9791559997915649 chr1 100110375 100110425 chr1 103414281 103414331 chr1105056441 105056491 chr10 125889077 125889127 chr1 107820276 107820326chr1 109807413 109807463 chr1 110287077 110287127 chr1 112336971112337021 chr1 112340213 112340263 chr1 112507004 112507054 chr1112828223 112828273 chr1 112882515 112882565 chr10 126253295 126253345chr1 115095593 115095643 chr10 126349833 126349883 chr10 126523450126523500 chr1 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Repeat Category MLT1A0 chr10 81611942 81611992 chr10 8322506883225118 chr17 46976620 46976670 chr17 53252158 53252208 chr17 6121032161210371 chr17 62949457 62949507 chr17 64026522 64026572 chr17 7064264070642690 chr17 71736042 71736092 chr17 73232506 73232556 chr17 7544345275443502 chr17 75613512 75613562 chr17 76177819 76177869 chr17 7688997276890022 chr17 77230554 77230604 chr17 77230477 77230527 chr17 7857928078579330 chr17 79310647 79310697 chr10 93320659 93320709 chr17 8168370681683756 chr18 3519165 3519215 chr18 3518978 3519028 chr18 49593854959435 chr18 7381839 7381889 chr10 94722546 94722596 chr18 1383345413833504 chr18 13935237 13935287 chr18 17913844 17913894 chr18 1901670619016756 chr18 19236242 19236292 chr18 20671551 20671601 chr18 2183691421836964 chr18 25074663 25074713 chr10 96724400 96724450 chr18 4524478345244833 chr18 46493576 46493626 chr18 46493517 46493567 chr18 4892375348923803 chr18 51774084 51774134 chr18 53456341 53456391 chr18 5765603157656081 chr18 60409439 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65903931 65903981 chr15 59826949 59826999 chr15 6206889662068946 chr15 67367632 67367682 chr15 76656241 76656291 chr15 7942221979422269 chr15 79872020 79872070 chr15 80102059 80102109 chr15 8131528481315334 chr15 81314781 81314831 chr15 83293665 83293715 chr15 8505200385052053 chr15 88380808 88380858 chr15 91705653 91705703 chr15 9699018396990233 chr15 98237763 98237813 chr16 1075700 1075750 chr16 12734751273525 chr16 4044254 4044304 chr16 5248174 5248224 chr16 53801615380211 chr16 5834873 5834923 chr16 7512964 7513014 chr10 7119631271196362 chr10 71196111 71196161 chr16 9240077 9240127 chr16 1558970315589753 chr16 17931782 17931832 chr16 18013410 18013460 chr16 1892135618921406 chr10 71624333 71624383 chr16 19734793 19734843 chr16 2431444324314493 chr10 72105072 72105122 chr16 28208462 28208512 chr16 2927605529276105 chr16 53693173 53693223 chr16 55890375 55890425 chr16 5859748258597532 chr16 58995414 58995464 chr16 62315749 62315799 chr16 6348527463485324 chr16 66497775 66497825 chr16 66762598 66762648 chr10 7405202074052070 chr16 73886506 73886556 chr16 73886385 73886435 chr16 7540178775401837 chr16 77589290 77589340 chr16 80121277 80121327 chr16 8012115080121200 chr16 82742980 82743030 chr10 74814408 74814458 chr10 7481467274814722 chr17 259399 259449 chr17 1436954 1437004 chr17 6279672 6279722chr17 6280400 6280450 chr17 7160274 7160324 chr17 9077327 9077377 chr1710116628 10116678 chr10 78848227 78848277 chr17 12321590 12321640 chr1715823865 15823915 chr17 16021779 16021829 chr17 16589602 16589652 chr1079356589 79356639 chr17 18370892 18370942 chr17 19016137 19016187 chr1719486515 19486565 chr17 27799718 27799768 chr17 32249238 32249288 Table15DA. Repeat Category MLT1A1 chr17 42389181 42389231 chr10 8204762482047674 chr17 47822557 47822607 chr17 49571045 49571095 chr17 5558114255581192 chr17 60775221 60775271 chr17 79652646 79652696 chr18 50178495017899 chr18 7128794 7128844 chr18 7341710 7341760 chr10 9560560295605652 chr10 95760596 95760646 chr18 38348176 38348226 chr18 4982817349828223 chr10 98244194 98244244 chr18 65801419 65801469 chr18 6801547168015521 chr10 102054584 102054634 chr19 13606603 13606653 chr1957357731 57357781 chr1 3508591 3508641 chr10 118119298 118119348 chr113329594 13329644 chr1 22803523 22803573 chr10 6296629 6296679 chr131822718 31822768 chr1 38623270 38623320 chr1 39916475 39916525 chr169999586 69999636 chr1 89491487 89491537 chr1 89490800 89490850 chr191971378 91971428 chr1 93360323 93360373 chr1 93360776 93360826 chr1112336971 112337021 chr1 112340213 112340263 chr10 126523450 126523500chr1 157979341 157979391 chr1 163039703 163039753 chr1 186091563186091613 chr1 201779602 201779652 chr10 130653697 130653747 chr1215347907 215347957 chr1 228452409 228452459 chr1 231909179 231909229chr1 234181411 234181461 chr10 132168598 132168648 chr1 242914268242914318 chr20 17425983 17426033 chr20 25214568 25214618 chr20 2521467725214727 chr20 25410958 25411008 chr20 38756863 38756913 chr20 4620287846202928 chr20 61559507 61559557 chr20 62993513 62993563 chr21 2230169122301741 chr21 26208640 26208690 chr21 26554072 26554122 chr21 3178813831788188 chr21 44028131 44028181 chr21 46221250 46221300 chr22 2168700721687057 chr22 23785817 23785867 chr22 32646888 32646938 chr22 3507806035078110 chr22 35528365 35528415 chr11 2314129 2314179 chr11 23381622338212 chr11 2338614 2338664 chr22 39032518 39032568 chr22 3954615239546202 chr22 46078808 46078858 chr22 46080758 46080808 chrX 60693246069374 chrX 6070646 6070696 chrX 9963176 9963226 chrX 12186608 12186658chr11 6732140 6732190 chr11 6731923 6731973 chrX 56378890 56378940 chrX62485450 62485500 chrX 101121222 101121272 chrX 104123657 104123707 chrX115685448 115685498 chrX 117279575 117279625 chrX 117534168 117534218chrX 126492679 126492729 chrX 131904454 131904504 chrY 9052531 9052581chrY 16330374 16330424 chr2 1070590 1070640 chr2 1764358 1764408 chr215748891 15748941 chr2 18031329 18031379 chr2 39246423 39246473 chr247317603 47317653 chr2 54218673 54218723 chr11 28484301 28484351 chr2109269484 109269534 chr2 130316228 130316278 chr2 150618504 150618554chr2 170593329 170593379 chr2 170780631 170780681 chr2 170902111170902161 chr11 40147681 40147731 chr2 204114085 204114135 chr2208729015 208729065 chr2 232029091 232029141 chr2 236256659 236256709chr2 238236795 238236845 chr11 45717457 45717507 chr2 239996012239996062 chr3 11757313 11757363 chr3 23152294 23152344 chr11 4805807248058122 chr3 52125602 52125652 chr3 95573782 95573832 chr3 105270010105270060 chr3 110388685 110388735 chr3 117717428 117717478 chr3121452504 121452554 chr3 129743515 129743565 chr3 139058402 139058452chr3 142349181 142349231 chr3 143039830 143039880 chr3 158351515158351565 chr3 186107482 186107532 chr11 63471638 63471688 chr3198334327 198334377 chr4 1609924 1609974 chr11 64700890 64700940 chr1165218662 65218712 chr4 63395615 63395665 chr4 63915993 63916043 chr467429475 67429525 chr4 67552484 67552534 chr4 69163433 69163483 chr4100340653 100340703 chr4 112504259 112504309 chr4 114860281 114860331chr4 130006317 130006367 chr4 130092495 130092545 chr4 131684430131684480 chr4 140395544 140395594 chr4 148125040 148125090 chr4149194409 149194459 chr4 154068479 154068529 chr4 155316431 155316481chr4 155316301 155316351 chr4 170865875 170865925 chr4 177549385177549435 chr4 183424077 183424127 chr4 186989358 186989408 chr4188156277 188156327 chr4 188156435 188156485 chr4 189675471 189675521chr5 1147906 1147956 chr5 10912750 10912800 chr5 12239006 12239056 chr518465138 18465188 chr5 18746772 18746822 chr5 18776817 18776867 chr520739594 20739644 chr5 26248755 26248805 chr5 28233868 28233918 chr578139794 78139844 chr5 99282775 99282825 chr5 108808701 108808751 chr5124793979 124794029 chr5 145927213 145927263 chr5 164922120 164922170chr5 171733637 171733687 chr5 177988629 177988679 chr6 3441172 3441222chr6 7267792 7267842 chr6 9290298 9290348 chr6 13320864 13320914 chr614176842 14176892 chr6 39084428 39084478 chr6 39843570 39843620 chr656219731 56219781 chr6 83708015 83708065 chr6 124725475 124725525 chr6131255497 131255547 chr6 132642644 132642694 chr6 158194965 158195015chr6 168145501 168145551 chr6 168145801 168145851 chr6 168352323168352373 chr6 168352795 168352845 chr6 170650606 170650656 chr729451979 29452029 chr7 32525446 32525496 chr7 43738532 43738582 chr750677319 50677369 chr7 72357940 72357990 chr7 124636855 124636905 chr1017612669 17612719 chr11 118845396 118845446 chr7 150543396 150543446chr7 158043621 158043671 chr7 158044757 158044807 chr10 1796649017966540 chr8 1719367 1719417 chr8 1719962 1720012 chr10 1821340018213450 chr8 2767365 2767415 chr8 11303063 11303113 chr8 2348909623489146 chr8 24904119 24904169 chr8 30185916 30185966 chr8 3918230339182353 chr8 42159046 42159096 chr8 55474525 55474575 chr8 6796629967966349 chr8 74178911 74178961 chr8 83188834 83188884 chr11 128348352128348402 chr8 120118514 120118564 chr8 127699054 127699104 chr8131776504 131776554 chr8 141098143 141098193 chr8 142939718 142939768chr8 144384107 144384157 chr8 145861459 145861509 chr9 6684291 6684341chr9 6904458 6904508 chr9 7118221 7118271 chr9 7118120 7118170 chr916390427 16390477 chr9 33687572 33687622 chr9 33687318 33687368 chr970493932 70493982 chr9 78819849 78819899 chr9 87390311 87390361 chr992223237 92223287 chr9 93488821 93488871 chr9 96417384 96417434 chr9110866344 110866394 chr9 110867319 110867369 chr12 1537752 1537802 chr121538352 1538402 chr9 127937322 127937372 chr9 130641227 130641277 chr1022196439 22196489 chr12 16166769 16166819 chr12 32267328 32267378 chr1242135594 42135644 chr12 47317207 47317257 chr10 27192759 27192809 chr1028812081 28812131 chr10 29300672 29300722 chr12 90875344 90875394 chr1292519973 92520023 chr12 92942700 92942750 chr12 94972803 94972853 chr12100317739 100317789 chr12 120443279 120443329 chr12 131786851 131786901chr12 131999569 131999619 chr13 19148845 19148895 chr13 1948265119482701 chr13 22480241 22480291 chr13 23199912 23199962 chr13 2586533625865386 chr13 38728265 38728315 chr13 49862648 49862698 chr13 5370729153707341 chr10 42366038 42366088 chr13 62274430 62274480 chr13 7865572878655778 chr13 85532201 85532251 chr13 97969087 97969137 chr10 4522771245227762 chr14 21708164 21708214 chr14 21916565 21916615 chr14 2211600722116057 chr14 25625906 25625956 chr14 27133030 27133080 chr14 4992848049928530 chr14 63901595 63901645 chr14 69426430 69426480 chr14 6960007569600125 chr14 69599905 69599955 chr14 73939807 73939857 chr14 8054492980544979 chr14 82569731 82569781 chr14 87363378 87363428 chr14 8774858087748630 chr14 91044551 91044601 chr14 92327056 92327106 chr14 100396278100396328 chr14 101031609 101031659 chr14 103308182 103308232 chr14103973354 103973404 chr15 22700248 22700298 chr15 42399105 42399155chr15 52039484 52039534 chr15 53600647 53600697 chr15 80119673 80119723chr15 84306899 84306949 chr16 6084208 6084258 chr16 9082351 9082401chr16 22903640 22903690 chr16 28314359 28314409 chr16 48167565 48167615chr16 48167453 48167503 chr16 52807808 52807858 chr16 56523367 56523417chr16 58244086 58244136 chr16 75279095 75279145 chr16 75333135 75333185chr16 77291255 77291305 chr16 89155353 89155403 chr16 89155217 89155267chr10 75790824 75790874 chr10 75790960 75791010 chr17 8456399 8456449chr17 10132106 10132156 chr10 79362760 79362810 Table 15DB. RepeatCategory MLT1D-int chr19 3685474 3685524 chr1 24722027 24722077 chr156328589 56328639 chr1 158518464 158518514 chr1 158520497 158520547 chr1230795152 230795202 chr21 23355943 23355993 chr21 44649714 44649764chr21 44650783 44650833 chr21 44651638 44651688 chr11 1454013 1454063chr11 1455289 1455339 chr22 22680954 22681004 chr22 39258564 39258614chr22 39261089 39261139 chrX 50505235 50505285 chrX 104987939 104987989chr2 57317578 57317628 chr11 28788279 28788329 chr2 123209273 123209323chr2 135078099 135078149 chr2 135079567 135079617 chr2 141639929141639979 chr2 231439665 231439715 chr3 138239288 138239338 chr430994830 30994880 chr11 70003455 70003505 chr6 66671001 66671051 chr76002660 6002710 chr7 108487440 108487490 chr7 128762156 128762206 chr842208643 42208693 chr8 144772578 144772628 chr8 145142425 145142475 chr9100455867 100455917 chr12 127724608 127724658 chr13 64467757 64467807chr16 59565312 59565362 Table 15DC. Repeat Category MLT1E chr17 4783136347831413 chr17 47833546 47833596 chr17 55740556 55740606 chr17 5939350459393554 chr17 64715790 64715840 chr17 65536725 65536775 chr17 6718777267187822 chr17 68490863 68490913 chr17 75657698 75657748 chr17 7657901576579065 chr17 78800988 78801038 chr17 79642713 79642763 chr18 31098333109883 chr18 8433646 8433696 chr18 12966642 12966692 chr18 1869821718698267 chr18 30045015 30045065 chr18 30607603 30607653 chr18 3162237631622426 chr18 32443928 32443978 chr18 32655270 32655320 chr18 3287164132871691 chr18 32894687 32894737 chr18 34074086 34074136 chr10 50138465013896 chr18 36514156 36514206 chr18 41972856 41972906 chr18 4235399142354041 chr18 46584992 46585042 chr18 49525078 49525128 chr18 5002195850022008 chr18 52856287 52856337 chr18 56276892 56276942 chr18 5681055556810605 chr18 58496275 58496325 chr18 63077178 63077228 chr18 6539615465396204 chr18 66710209 66710259 chr18 73517328 73517378 chr18 7426523674265286 chr19 329657 329707 chr19 1118055 1118105 chr19 1290155 1290205chr19 1691821 1691871 chr19 2278146 2278196 chr19 3502015 3502065 chr194290134 4290184 chr19 4290360 4290410 chr19 4618040 4618090 chr196594897 6594947 chr19 9418830 9418880 chr19 13191417 13191467 chr1914260698 14260748 chr19 19578424 19578474 chr19 21557352 21557402 chr1921556880 21556930 chr19 23187662 23187712 chr19 37671585 37671635 chr1940156262 40156312 chr10 105862554 105862604 chr19 47698558 47698608chr19 49750219 49750269 chr19 59148441 59148491 chr19 59678885 59678935chr19 60673203 60673253 chr19 60674467 60674517 chr19 60990494 60990544chr19 63361953 63362003 chr19 63690504 63690554 chr1 3716912 3716962chr1 3825639 3825689 chr1 7883054 7883104 chr1 9000468 9000518 chr113148248 13148298 chr1 23841184 23841234 chr1 26757461 26757511 chr127010871 27010921 chr1 37686990 37687040 chr1 39494845 39494895 chr141138946 41138996 chr1 59489448 59489498 chr1 63234548 63234598 chr164594611 64594661 chr1 70284792 70284842 chr1 73172795 73172845 chr185407219 85407269 chr1 85407141 85407191 chr10 6684743 6684793 chr194913420 94913470 chr1 94913735 94913785 chr1 94914117 94914167 chr1105674740 105674790 chr1 119421025 119421075 chr1 119420802 119420852chr1 144829958 144830008 chr1 157982695 157982745 chr1 160580408160580458 chr1 164685897 164685947 chr1 165297962 165298012 chr1166644595 166644645 chr1 172765596 172765646 chr1 172765343 172765393chr10 129675692 129675742 chr1 189103439 189103489 chr1 191914983191915033 chr1 195544555 195544605 chr1 216740268 216740318 chr1223197391 223197441 chr1 223705206 223705256 chr1 225239001 225239051chr1 225238803 225238853 chr1 233176681 233176731 chr10 131636869131636919 chr1 241770014 241770064 chr1 243813655 243813705 chr1244547850 244547900 chr20 669783 669833 chr20 3043556 3043606 chr205642968 5643018 chr20 9185330 9185380 chr20 17168886 17168936 chr2017836425 17836475 chr20 17836216 17836266 chr20 20259800 20259850 chr2030766345 30766395 chr10 133469033 133469083 chr10 133468972 133469022chr10 133841192 133841242 chr20 44125679 44125729 chr20 5061643650616486 chr20 53230999 53231049 chr20 53919098 53919148 chr20 5422108154221131 chr20 55005483 55005533 chr20 55801676 55801726 chr20 5635379456353844 chr20 56578425 56578475 chr20 58396502 58396552 chr20 5991005759910107 chr20 62140316 62140366 chr20 62265276 62265326 chr20 6286361362863663 chr21 10087446 10087496 chr21 18272127 18272177 chr21 1842218218422232 chr21 22562168 22562218 chr21 31130187 31130237 chr21 3132419931324249 chr21 31324811 31324861 chr21 31746148 31746198 chr21 3364040833640458 chr21 34802071 34802121 chr21 34802604 34802654 chr21 3757118037571230 chr21 44430106 44430156 chr21 44440619 44440669 chr21 4445400744454057 chr21 44454910 44454960 chr21 44454737 44454787 chr21 4507347645073526 chr21 45409810 45409860 chr21 45525063 45525113 chr21 4622125046221300 chr21 46222157 46222207 chr21 46286537 46286587 chr21 4635718546357235 chr21 46472555 46472605 chr21 46473125 46473175 chr22 1814733518147385 chr22 19189270 19189320 chr22 28317612 28317662 chr22 2909885929098909 chr22 31668958 31669008 chr22 31823553 31823603 chr22 3213787032137920 chr22 34097825 34097875 chr22 35154982 35155032 chr22 4373285743732907 chr22 47854320 47854370 chr22 48160123 48160173 chr22 4818269148182741 chrX 6809179 6809229 chrX 6809112 6809162 chrX 1336356513363615 chrX 14620027 14620077 chrX 14739785 14739835 chrX 2179106721791117 chrX 23199210 23199260 chrX 23501868 23501918 chrX 2600464126004691 chrX 35056983 35057033 chrX 35290601 35290651 chr11 67321406732190 chrX 43494342 43494392 chrX 43696223 43696273 chrX 4496493544964985 chrX 49663992 49664042 chrX 55961522 55961572 chrX 6406272964062779 chrX 72004917 72004967 chrX 86355721 86355771 chrX 8694604286946092 chrX 92270844 92270894 chrX 94608237 94608287 chrX 105149088105149138 chrX 110026541 110026591 chr11 10556227 10556277 chr1110556684 10556734 chr11 10556750 10556800 chrX 128774648 128774698 chrX130089934 130089984 chrX 130408767 130408817 chrX 140290782 140290832chrX 144308906 144308956 chrX 152949555 152949605 chrY 4552353 4552403chrY 15599217 15599267 chr2 2022813 2022863 chr2 2832036 2832086 chr24816808 4816858 chr2 4816632 4816682 chr2 5543347 5543397 chr11 1767805517678105 chr2 19225058 19225108 chr2 19520116 19520166 chr2 2089535320895403 chr2 23326847 23326897 chr10 11814038 11814088 chr2 8190292281902972 chr11 31030017 31030067 chr2 121160429 121160479 chr2 122247202122247252 chr2 132882192 132882242 chr2 146157555 146157605 chr2147798908 147798958 chr2 166993330 166993380 chr11 35907226 35907276chr2 170762171 170762221 chr2 171933491 171933541 chr2 191819513191819563 chr2 191852250 191852300 chr2 195726434 195726484 chr2196582938 196582988 chr2 196584147 196584197 chr11 39333875 39333925chr2 202628331 202628381 chr2 208508603 208508653 chr11 4211764342117693 chr11 42337461 42337511 chr2 225166052 225166102 chr2 226019697226019747 chr2 229535737 229535787 chr2 229621126 229621176 chr2236301651 236301701 chr2 239833185 239833235 chr2 240546021 240546071chr2 240896499 240896549 chr11 46137660 46137710 chr3 3685495 3685545chr3 21627246 21627296 chr3 21700082 21700132 chr3 22197795 22197845chr3 23722812 23722862 chr3 37166996 37167046 chr11 47871256 47871306chr3 42412715 42412765 chr3 42412465 42412515 chr3 42498317 42498367chr3 46758851 46758901 chr3 59382295 59382345 chr3 59382192 59382242chr11 57172786 57172836 chr3 66582899 66582949 chr3 77739751 77739801chr3 81846521 81846571 chr3 86881111 86881161 chr3 95632183 95632233chr3 102850422 102850472 chr3 102908967 102909017 chr3 127171332127171382 chr3 130057005 130057055 chr3 131233285 131233335 chr3132690194 132690244 chr3 137705213 137705263 chr3 142968468 142968518chr3 142968378 142968428 chr3 152952931 152952981 chr3 156279560156279610 chr3 156279468 156279518 chr3 164930849 164930899 chr3172320890 172320940 chr3 175749358 175749408 chr3 178311695 178311745chr3 195873836 195873886 chr11 63525125 63525175 chr4 2249702 2249752chr4 3775205 3775255 chr4 4078325 4078375 chr4 4204483 4204533 chr49255641 9255691 chr4 16434193 16434243 chr4 16496468 16496518 chr417743014 17743064 chr4 21937470 21937520 chr4 21982637 21982687 chr422497116 22497166 chr4 26770351 26770401 chr4 26770292 26770342 chr433558999 33559049 chr4 35295748 35295798 chr4 38273593 38273643 chr439929681 39929731 chr4 55108506 55108556 chr4 68344529 68344579 chr478363184 78363234 chr4 81743745 81743795 chr4 92045141 92045191 chr496028975 96029025 chr4 96780225 96780275 chr4 131700058 131700108 chr4132974327 132974377 chr4 142706444 142706494 chr4 142706241 142706291chr4 160937083 160937133 chr4 160937262 160937312 chr4 163844864163844914 chr4 168460292 168460342 chr4 168460405 168460455 chr4168460636 168460686 chr4 168460856 168460906 chr4 169125144 169125194chr4 171177177 171177227 chr4 174542348 174542398 chr4 177807252177807302 chr4 180740683 180740733 chr4 184837525 184837575 chr1167969001 67969051 chr4 186207917 186207967 chr4 186209986 186210036 chr4186210138 186210188 chr4 189498010 189498060 chr4 189851035 189851085chr11 68590792 68590842 chr5 1436087 1436137 chr5 8346930 8346980 chr515920994 15921044 chr5 16866919 16866969 chr5 17550893 17550943 chr517674466 17674516 chr5 17698190 17698240 chr5 20650808 20650858 chr521188635 21188685 chr5 22161951 22162001 chr5 23370499 23370549 chr533279928 33279978 chr5 36834733 36834783 chr5 37426668 37426718 chr544995165 44995215 chr5 49777809 49777859 chr5 58937478 58937528 chr568149252 68149302 chr5 68591236 68591286 chr5 70768204 70768254 chr574281084 74281134 chr5 78280975 78281025 chr5 83930019 83930069 chr584359062 84359112 chr5 96223920 96223970 chr5 96223831 96223881 chr597894081 97894131 chr5 99659307 99659357 chr5 99876197 99876247 chr5108095800 108095850 chr5 110087810 110087860 chr5 114656062 114656112chr5 117365367 117365417 chr5 123354510 123354560 chr5 128976009128976059 chr10 14612842 14612892 chr11 73994890 73994940 chr10 1465603214656082 chr5 172417971 172418021 chr5 176817836 176817886 chr5176818537 176818587 chr5 177703831 177703881 chr5 178017199 178017249chr5 179728503 179728553 chr5 179739647 179739697 chr11 7675095076751000 chr11 76755216 76755266 chr6 2302240 2302290 chr11 7691659376916643 chr6 3120230 3120280 chr6 5922901 5922951 chr6 6226915 6226965chr6 8393893 8393943 chr6 10279733 10279783 chr6 15107176 15107226 chr615329248 15329298 chr6 18402408 18402458 chr11 80427901 80427951 chr630013905 30013955 chr6 48613004 48613054 chr6 54297963 54298013 chr665357455 65357505 chr6 66948363 66948413 chr6 84668687 84668737 chr684668443 84668493 chr6 94439856 94439906 chr6 98763579 98763629 chr6103294987 103295037 chr6 103462261 103462311 chr6 107130051 107130101chr6 110893963 110894013 chr6 113480283 113480333 chr6 114904747114904797 chr6 115232969 115233019 chr6 123177975 123178025 chr6130973613 130973663 chr6 140543421 140543471 chr6 146472859 146472909chr6 146472598 146472648 chr6 150935692 150935742 chr6 157931284157931334 chr6 162618483 162618533 chr6 162618970 162619020 chr6162618710 162618760 chr6 163974095 163974145 chr6 163974177 163974227chr6 164696499 164696549 chr6 165343844 165343894 chr6 165883566165883616 chr6 166580567 166580617 chr6 166581842 166581892 chr11105567462 105567512 chr7 227093 227143 chr7 2009656 2009706 chr7 25410502541100 chr7 2542692 2542742 chr7 2602788 2602838 chr7 3739170 3739220chr11 108553805 108553855 chr7 4598522 4598572 chr7 4921226 4921276 chr77365966 7366016 chr7 24478207 24478257 chr7 35194389 35194439 chr744999757 44999807 chr7 46766467 46766517 chr7 48099671 48099721 chr749297205 49297255 chr7 49886350 49886400 chr7 51711497 51711547 chr756959364 56959414 chr7 63174518 63174568 chr7 63378302 63378352 chr767727538 67727588 chr7 68988411 68988461 chr7 81776591 81776641 chr790277525 90277575 chr7 90698367 90698417 chr7 109179048 109179098 chr7117833906 117833956 chr7 135550670 135550720 chr7 140941959 140942009chr7 145016385 145016435 chr11 119180074 119180124 chr7 152109282152109332 chr7 158367986 158368036 chr8 600387 600437 chr8 600706 600756chr8 2918923 2918973 chr8 4040892 4040942 chr8 4616838 4616888 chr85452171 5452221 chr11 124059447 124059497 chr8 32451750 32451800 chr834602931 34602981 chr8 41363422 41363472 chr8 61489135 61489185 chr11125514648 125514698 chr11 125819610 125819660 chr8 80353864 80353914chr8 84923672 84923722 chr8 91391603 91391653 chr8 104758130 104758180chr11 128313590 128313640 chr8 107914805 107914855 chr8 109899259109899309 chr8 112720251 112720301 chr8 114627581 114627631 chr8114775405 114775455 chr8 117372070 117372120 chr8 118485921 118485971chr10 19196079 19196129 chr8 135728319 135728369 chr8 139902855139902905 chr8 142592164 142592214 chr8 144314346 144314396 chr8144621426 144621476 chr8 144943066 144943116 chr9 2738496 2738546 chr915083012 15083062 chr11 132392491 132392541 chr11 132392372 132392422chr9 15552274 15552324 chr9 23469176 23469226 chr11 132823075 132823125chr9 27622227 27622277 chr9 30080616 30080666 chr11 133203912 133203962chr9 34669728 34669778 chr9 38473512 38473562 chr9 73253139 73253189chr9 76436141 76436191 chr9 81140121 81140171 chr9 82198898 82198948chr9 92687906 92687956 chr9 98261589 98261639 chr9 103455573 103455623chr9 106050739 106050789 chr9 119808920 119808970 chr9 130941445130941495 chr12 2755981 2756031 chr9 132812854 132812904 chr9 134060962134061012 chr9 134280729 134280779 chr9 135706488 135706538 chr1021987921 21987971 chr10 23606945 23606995 chr10 1103757 1103807 chr1222488703 22488753 chr12 25870042 25870092 chr12 30457769 30457819 chr1230806774 30806824 chr12 41380329 41380379 chr12 46901752 46901802 chr1250205742 50205792 chr12 56591105 56591155 chr12 62960866 62960916 chr1273238994 73239044 chr12 74349511 74349561 chr12 84624791 84624841 chr1029463578 29463628 chr12 88190443 88190493 chr12 88757561 88757611 chr1289858467 89858517 chr12 93824643 93824693 chr12 107741709 107741759chr12 115490829 115490879 chr12 116976780 116976830 chr10 3251724732517297 chr12 123559989 123560039 chr12 123572104 123572154 chr12124482877 124482927 chr12 124489955 124490005 chr12 124988593 124988643chr12 124990006 124990056 chr12 126281682 126281732 chr12 126881269126881319 chr12 128649374 128649424 chr12 131166680 131166730 chr1329863915 29863965 chr10 37212001 37212051 chr13 32090042 32090092 chr1332462730 32462780 chr13 34514930 34514980 chr13 41019904 41019954 chr1038172937 38172987 chr13 44949681 44949731 chr13 44949176 44949226 chr1346310985 46311035 chr13 49087193 49087243 chr13 49242585 49242635 chr1364163906 64163956 chr13 66060461 66060511 chr13 76150254 76150304 chr1379571623 79571673 chr13 84853777 84853827 chr13 87688039 87688089 chr1388850597 88850647 chr13 105537151 105537201 chr13 109663122 109663172chr13 111275971 111276021 chr10 47846115 47846165 chr14 3856120738561257 chr14 43508332 43508382 chr14 51358080 51358130 chr14 6253857562538625 chr10 1866112 1866162 chr10 1866058 1866108 chr14 7621896776219017 chr14 76427788 76427838 chr10 54803155 54803205 chr14 8950094589500995 chr10 55777194 55777244 chr14 93307052 93307102 chr14 9971379399713843 chr14 99713554 99713604 chr14 102669904 102669954 chr14102882202 102882252 chr14 103480824 103480874 chr14 103611335 103611385chr14 103726056 103726106 chr15 20306201 20306251 chr15 2078383520783885 chr15 22688962 22689012 chr15 23695006 23695056 chr15 2369480523694855 chr15 27394543 27394593 chr15 29203465 29203515 chr15 3065435630654406 chr15 36118709 36118759 chr15 49313440 49313490 chr15 5383321153833261 chr15 54621186 54621236 chr10 66573792 66573842 chr15 6904866069048710 chr15 88846391 88846441 chr15 89300669 89300719 chr16 439124439174 chr16 440001 440051 chr10 70241432 70241482 chr10 7024166970241719 chr16 5079413 5079463 chr16 5879045 5879095 chr16 61888046188854 chr16 7512964 7513014 chr16 16541151 16541201 chr16 1802048918020539 chr16 18291725 18291775 chr16 25297275 25297325 chr16 2555180825551858 chr16 48213334 48213384 chr16 56032184 56032234 chr10 7326564473265694 chr16 59492617 59492667 chr16 62512910 62512960 chr16 6276508662765136 chr16 76448548 76448598 chr16 77232267 77232317 chr16 8581959985819649 chr10 75098284 75098334 chr10 76069850 76069900 chr10 7634532776345377 chr10 76442077 76442127 chr10 79039069 79039119 chr17 2639077026390820 chr17 29473237 29473287 Table 15DD. Repeat Category MLT1E2chr17 75657698 75657748 chr17 78800988 78801038 chr17 79642713 79642763chr18 30045015 30045065 chr18 30607603 30607653 chr18 32655270 32655320chr18 32871641 32871691 chr18 36514156 36514206 chr18 49525078 49525128chr18 63077178 63077228 chr18 65396154 65396204 chr18 66710209 66710259chr18 73517328 73517378 chr18 74265236 74265286 chr19 329657 329707chr19 1118055 1118105 chr19 1290155 1290205 chr19 4290134 4290184 chr194290360 4290410 chr19 14260698 14260748 chr19 21557352 21557402 chr1921556880 21556930 chr19 47698558 47698608 chr19 59678885 59678935 chr19000468 9000518 chr1 23841184 23841234 chr1 37686990 37687040 chr159489448 59489498 chr1 64594611 64594661 chr1 70284792 70284842 chr185407219 85407269 chr1 85407141 85407191 chr1 160580408 160580458 chr1165297962 165298012 chr1 166644595 166644645 chr1 195544555 195544605chr1 216740268 216740318 chr1 241770014 241770064 chr1 243813655243813705 chr1 244547850 244547900 chr20 669783 669833 chr20 56429685643018 chr20 44125679 44125729 chr20 50616436 50616486 chr20 5635379456353844 chr20 58396502 58396552 chr20 59910057 59910107 chr20 6214031662140366 chr21 10087446 10087496 chr21 18272127 18272177 chr21 2256216822562218 chr21 31324199 31324249 chr21 31324811 31324861 chr21 3757118037571230 chr21 44454007 44454057 chr21 44454910 44454960 chr21 4445473744454787 chr21 45073476 45073526 chr21 45525063 45525113 chr22 1918927019189320 chr22 31668958 31669008 chr22 32137870 32137920 chr22 3409782534097875 chr22 47854320 47854370 chrX 6809179 6809229 chrX 68091126809162 chrX 35290601 35290651 chrX 49663992 49664042 chrX 5596152255961572 chrX 86355721 86355771 chrX 105149088 105149138 chr11 1055622710556277 chr11 10556684 10556734 chr11 10556750 10556800 chrX 130089934130089984 chrX 130408767 130408817 chrY 4552353 4552403 chr2 55433475543397 chr11 17678055 17678105 chr2 20895353 20895403 chr2 8190292281902972 chr11 31030017 31030067 chr2 132882192 132882242 chr2 171933491171933541 chr2 196582938 196582988 chr2 196584147 196584197 chr2208508603 208508653 chr11 42337461 42337511 chr2 225166052 225166102chr2 226019697 226019747 chr2 229535737 229535787 chr2 229621126229621176 chr3 3685495 3685545 chr3 21700082 21700132 chr3 4241271542412765 chr3 42412465 42412515 chr3 59382295 59382345 chr3 5938219259382242 chr3 77739751 77739801 chr3 86881111 86881161 chr3 9563218395632233 chr3 102908967 102909017 chr3 127171332 127171382 chr3130057005 130057055 chr3 137705213 137705263 chr3 142968468 142968518chr3 142968378 142968428 chr3 172320890 172320940 chr11 6352512563525175 chr4 3775205 3775255 chr4 21982637 21982687 chr4 2249711622497166 chr4 33558999 33559049 chr4 68344529 68344579 chr4 8174374581743795 chr4 92045141 92045191 chr4 131700058 131700108 chr4 142706444142706494 chr4 142706241 142706291 chr4 163844864 163844914 chr4169125144 169125194 chr4 174542348 174542398 chr4 177807252 177807302chr4 180740683 180740733 chr4 184837525 184837575 chr11 6859079268590842 chr5 15920994 15921044 chr5 16866919 16866969 chr5 2216195122162001 chr5 23370499 23370549 chr5 37426668 37426718 chr5 6814925268149302 chr5 68591236 68591286 chr5 70768204 70768254 chr5 7828097578281025 chr5 97894081 97894131 chr5 108095800 108095850 chr5 110087810110087860 chr5 114656062 114656112 chr5 117365367 117365417 chr5123354510 123354560 chr5 128976009 128976059 chr5 177703831 177703881chr6 2302240 2302290 chr6 5922901 5922951 chr6 6226915 6226965 chr610279733 10279783 chr6 66948363 66948413 chr6 84668687 84668737 chr684668443 84668493 chr6 103294987 103295037 chr6 103462261 103462311 chr6113480283 113480333 chr6 115232969 115233019 chr6 146472859 146472909chr6 146472598 146472648 chr6 150935692 150935742 chr6 157931284157931334 chr6 164696499 164696549 chr6 165343844 165343894 chr6165883566 165883616 chr7 227093 227143 chr7 3739170 3739220 chr7 45985224598572 chr7 4921226 4921276 chr7 24478207 24478257 chr7 4499975744999807 chr7 49886350 49886400 chr7 63174518 63174568 chr7 6772753867727588 chr7 90698367 90698417 chr7 109179048 109179098 chr7 135550670135550720 chr7 140941959 140942009 chr8 4616838 4616888 chr8 54521715452221 chr11 124059447 124059497 chr8 34602931 34602981 chr8 4136342241363472 chr8 61489135 61489185 chr11 125514648 125514698 chr11125819610 125819660 chr8 107914805 107914855 chr8 112720251 112720301chr8 118485921 118485971 chr8 139902855 139902905 chr8 142592164142592214 chr8 144314346 144314396 chr9 2738496 2738546 chr9 1508301215083062 chr9 23469176 23469226 chr11 132823075 132823125 chr9 3008061630080666 chr9 73253139 73253189 chr9 92687906 92687956 chr9 106050739106050789 chr9 119808920 119808970 chr9 130941445 130941495 chr9134060962 134061012 chr9 135706488 135706538 chr10 21987921 21987971chr12 22488703 22488753 chr12 25870042 25870092 chr12 56591105 56591155chr12 88757561 88757611 chr10 32517247 32517297 chr12 124482877124482927 chr12 124489955 124490005 chr12 124988593 124988643 chr12124990006 124990056 chr12 128649374 128649424 chr12 131166680 131166730chr10 37212001 37212051 chr13 32090042 32090092 chr13 46310985 46311035chr13 49087193 49087243 chr13 84853777 84853827 chr13 88850597 88850647chr13 105537151 105537201 chr14 43508332 43508382 chr14 5135808051358130 chr10 1866112 1866162 chr10 1866058 1866108 chr14 8950094589500995 chr14 102669904 102669954 chr14 103480824 103480874 chr14103726056 103726106 chr15 20783835 20783885 chr15 49313440 49313490chr15 53833211 53833261 chr16 5079413 5079463 chr16 7512964 7513014chr16 48213334 48213384 chr16 56032184 56032234 chr10 73265644 73265694chr16 62512910 62512960 chr16 85819599 85819649 chr10 76069850 76069900chr10 79039069 79039119 Table 15DE. Repeat Category MLT1F chr17 3907168639071736 chr17 45871163 45871213 chr17 47838548 47838598 chr17 5910469359104743 chr17 59217273 59217323 chr17 67224841 67224891 chr17 7174386671743916 chr17 72666581 72666631 chr17 74034896 74034946 chr17 7458074574580795 chr17 75164482 75164532 chr17 76835361 76835411 chr17 7683675576836805 chr17 80086590 80086640 chr10 92621546 92621596 chr17 8062148080621530 chr10 93909856 93909906 chr18 11922659 11922709 chr10 9497478194974831 chr18 22826965 22827015 chr18 24382754 24382804 chr10 9579634695796396 chr18 36675429 36675479 chr18 36866944 36866994 chr18 4202849142028541 chr18 46104346 46104396 chr18 53440600 53440650 chr18 5359473253594782 chr18 58068017 58068067 chr18 58631226 58631276 chr18 7381706373817113 chr18 75834630 75834680 chr19 463625 463675 chr19 23178792317929 chr19 2611249 2611299 chr19 2692173 2692223 chr19 36120263612076 chr19 4770977 4771027 chr10 101648692 101648742 chr10 101870440101870490 chr19 8795787 8795837 chr19 8998136 8998186 chr19 91832059183255 chr19 12795021 12795071 chr19 13712633 13712683 chr19 1744636317446413 chr19 39558813 39558863 chr19 41353556 41353606 chr19 4272710442727154 chr19 45848729 45848779 chr19 48593167 48593217 chr19 4863358548633635 chr19 48633735 48633785 chr10 107983467 107983517 chr1950398924 50398974 chr19 51772260 51772310 chr19 51772894 51772944 chr1953844730 53844780 chr19 53973015 53973065 chr19 55018409 55018459 chr1955039196 55039246 chr19 59559100 59559150 chr19 59602322 59602372 chr1960415782 60415832 chr19 61598756 61598806 chr19 63363298 63363348 chr1963568373 63568423 chr1 3738472 3738522 chr10 116031715 116031765 chr16580096 6580146 chr1 7633036 7633086 chr1 9450768 9450818 chr1 1155106911551119 chr1 14216346 14216396 chr1 14400976 14401026 chr1 1440077714400827 chr1 15440057 15440107 chr1 16172507 16172557 chr1 1617280016172850 chr1 22664179 22664229 chr1 23571768 23571818 chr1 2436961924369669 chr1 25784989 25785039 chr1 27927355 27927405 chr10 120555242120555292 chr1 29893133 29893183 chr1 32500238 32500288 chr1 6314411163144161 chr1 64232586 64232636 chr10 6610343 6610393 chr1 7272219472722244 chr1 73031388 73031438 chr1 88978115 88978165 chr1 8901696189017011 chr1 102593718 102593768 chr1 111518427 111518477 chr1113009981 113010031 chr1 114342224 114342274 chr1 117852193 117852243chr10 127655663 127655713 chr1 176475850 176475900 chr1 187254490187254540 chr1 187924409 187924459 chr1 200937916 200937966 chr1201094375 201094425 chr1 210311915 210311965 chr1 215853149 215853199chr1 216826289 216826339 chr1 228974382 228974432 chr1 235647318235647368 chr1 242105657 242105707 chr1 242806821 242806871 chr20 296177296227 chr20 802400 802450 chr20 2559772 2559822 chr20 5615696 5615746chr20 5797290 5797340 chr20 5938312 5938362 chr20 11533963 11534013chr20 13615816 13615866 chr10 133069071 133069121 chr20 1587870015878750 chr20 20389642 20389692 chr20 31580933 31580983 chr10 133624391133624441 chr20 36653150 36653200 chr20 40223237 40223287 chr20 4358456543584615 chr20 45812921 45812971 chr20 49973245 49973295 chr20 5063623450636284 chr20 53154699 53154749 chr20 55595415 55595465 chr20 6206269462062744 chr20 62346837 62346887 chr21 15083139 15083189 chr21 1593988315939933 chr21 20233422 20233472 chr21 29393901 29393951 chr21 3003845430038504 chr10 8342517 8342567 chr21 32770629 32770679 chr21 3322816933228219 chr21 36192720 36192770 chr21 41906570 41906620 chr21 4315994943159999 chr21 43160065 43160115 chr21 43168233 43168283 chr21 4412163744121687 chr21 44215130 44215180 chr21 46307911 46307961 chr22 1603201416032064 chr22 16309519 16309569 chr22 23830018 23830068 chr22 2594764125947691 chr22 29865663 29865713 chr22 34759928 34759978 chr22 3777524337775293 chr22 40138192 40138242 chr22 41298475 41298525 chr22 4180376941803819 chr22 42841855 42841905 chr22 46526694 46526744 chr22 4801175848011808 chr22 48075796 48075846 chr22 48305361 48305411 chrX 1347805513478105 chrX 14177519 14177569 chrX 17142311 17142361 chrX 2304286723042917 chrX 23841302 23841352 chrX 37585931 37585981 chrX 3934521639345266 chrX 39950710 39950760 chrX 42487008 42487058 chr11 69988746998924 chrX 45576963 45577013 chr11 7224408 7224458 chr11 72242657224315 chrX 46789669 46789719 chrX 47467972 47468022 chrX 4790555047905600 chrX 49068576 49068626 chrX 52184140 52184190 chrX 5316675153166801 chrX 68240643 68240693 chrX 75982250 75982300 chrX 9556502395565073 chrX 95709686 95709736 chrX 95760737 95760787 chrX 9947345099473500 chrX 109817441 109817491 chrX 112745887 112745937 chrX114849536 114849586 chr11 10829493 10829543 chrX 147054063 147054113chrX 148811891 148811941 chrX 151740030 151740080 chrX 152532071152532121 chr2 3267055 3267105 chr2 8713031 8713081 chr2 8712900 8712950chr2 25552423 25552473 chr2 25552257 25552307 chr2 32434102 32434152chr2 39347781 39347831 chr2 39513076 39513126 chr2 43038139 43038189chr2 43210108 43210158 chr2 43209868 43209918 chr2 43804502 43804552chr2 48815338 48815388 chr2 53861149 53861199 chr2 58589343 58589393chr2 61012801 61012851 chr2 62610051 62610101 chr11 23996085 23996135chr11 24400944 24400994 chr11 24706487 24706537 chr2 74335998 74336048chr2 74854815 74854865 chr2 75843543 75843593 chr11 26906526 26906576chr2 77329427 77329477 chr2 78773086 78773136 chr2 81729245 81729295chr2 85281450 85281500 chr11 27783359 27783409 chr2 86900893 86900943chr2 87303336 87303386 chr2 88928806 88928856 chr2 95369412 95369462chr2 96900864 96900914 chr11 30123860 30123910 chr11 31992190 31992240chr2 110474129 110474179 chr2 110962301 110962351 chr2 113111019113111069 chr2 113302667 113302717 chr2 113784854 113784904 chr2119625761 119625811 chr2 122662146 122662196 chr2 129216610 129216660chr2 135054116 135054166 chr2 136140851 136140901 chr2 140962477140962527 chr2 141134765 141134815 chr2 145205977 145206027 chr2152384223 152384273 chr2 160006282 160006332 chr2 170765919 170765969chr2 181085617 181085667 chr2 193960514 193960564 chr2 200971337200971387 chr2 203744139 203744189 chr2 204384541 204384591 chr2216166647 216166697 chr2 216959021 216959071 chr2 220207353 220207403chr2 220207448 220207498 chr2 222409950 222410000 chr2 232352055232352105 chr2 234434348 234434398 chr2 238054837 238054887 chr2239331752 239331802 chr2 239421836 239421886 chr2 241876510 241876560chr3 5250591 5250641 chr3 9559873 9559923 chr3 15668855 15668905 chr326379414 26379464 chr3 30439007 30439057 chr3 38987586 38987636 chr340525481 40525531 chr3 44902314 44902364 chr3 44902084 44902134 chr346010834 46010884 chr3 47926805 47926855 chr3 49920556 49920606 chr351612041 51612091 chr3 57878943 57878993 chr3 61224280 61224330 chr362067849 62067899 chr3 62067620 62067670 chr3 65785787 65785837 chr367697260 67697310 chr3 68984356 68984406 chr3 68984421 68984471 chr3101449845 101449895 chr3 106260175 106260225 chr3 107499192 107499242chr3 110461564 110461614 chr3 112627691 112627741 chr3 112691317112691367 chr3 114867932 114867982 chr3 114867746 114867796 chr3125582950 125583000 chr3 128911181 128911231 chr3 129747404 129747454chr3 147103290 147103340 chr3 147103117 147103167 chr3 151407114151407164 chr3 159626951 159627001 chr3 161518181 161518231 chr3162076618 162076668 chr3 162309553 162309603 chr10 12887684 12887734chr3 178298415 178298465 chr3 184939170 184939220 chr3 184940529184940579 chr3 188120135 188120185 chr11 62987799 62987849 chr3192279985 192280035 chr3 193877524 193877574 chr4 694204 694254 chr41613199 1613249 chr4 2791685 2791735 chr4 3338388 3338438 chr4 46521754652225 chr4 4651920 4651970 chr4 7780612 7780662 chr4 18028303 18028353chr4 20846736 20846786 chr4 25454091 25454141 chr4 36540280 36540330chr4 38493723 38493773 chr4 39540115 39540165 chr4 44781742 44781792chr4 46650075 46650125 chr4 48047970 48048020 chr4 54854841 54854891chr4 55921132 55921182 chr4 57510914 57510964 chr4 59077222 59077272chr4 60928132 60928182 chr4 82109015 82109065 chr4 84283546 84283596chr11 65716047 65716097 chr4 86003460 86003510 chr4 96101259 96101309chr4 97108007 97108057 chr4 107045807 107045857 chr4 107667990 107668040chr4 112504259 112504309 chr4 114258881 114258931 chr4 115231995115232045 chr4 121540640 121540690 chr4 126352019 126352069 chr4129056103 129056153 chr4 130092495 130092545 chr4 130162847 130162897chr11 66511904 66511954 chr4 133391388 133391438 chr4 135297915135297965 chr4 151710205 151710255 chr4 151709982 151710032 chr4152136944 152136994 chr11 67089836 67089886 chr4 160872855 160872905chr4 161477188 161477238 chr4 166336872 166336922 chr4 175532466175532516 chr4 178080590 178080640 chr4 182706449 182706499 chr4188118314 188118364 chr4 188118752 188118802 chr4 188716207 188716257chr4 190254153 190254203 chr5 245287 245337 chr5 1014793 1014843 chr51986979 1987029 chr5 6075012 6075062 chr5 8616246 8616296 chr5 1065741310657463 chr5 21144909 21144959 chr5 29312782 29312832 chr5 3222228232222332 chr5 34978124 34978174 chr5 35578581 35578631 chr5 3854688938546939 chr5 39371066 39371116 chr5 45483914 45483964 chr5 5379401253794062 chr5 58180120 58180170 chr11 70471508 70471558 chr5 7100282271002872 chr5 74061942 74061992 chr5 74917467 74917517 chr5 7630486576304915 chr5 76501677 76501727 chr5 84377335 84377385 chr5 8551380285513852 chr5 103113882 103113932 chr5 106157293 106157343 chr5112068206 112068256 chr5 112480144 112480194 chr5 119159793 119159843chr5 122147062 122147112 chr5 126218141 126218191 chr5 130569114130569164 chr5 130921674 130921724 chr5 132426356 132426406 chr5134225133 134225183 chr5 138132013 138132063 chr5 138133653 138133703chr5 138199022 138199072 chr5 138347842 138347892 chr5 138668032138668082 chr5 139387481 139387531 chr5 139488762 139488812 chr5139501048 139501098 chr5 139609129 139609179 chr5 140111602 140111652chr5 141459637 141459687 chr5 156497695 156497745 chr5 171892389171892439 chr5 172965556 172965606 chr5 174626794 174626844 chr5175327127 175327177 chr5 176483897 176483947 chr5 179933852 179933902chr5 180689794 180689844 chr6 1191585 1191635 chr6 2902347 2902397 chr63817648 3817698 chr6 5012208 5012258 chr6 6552255 6552305 chr6 1360926813609318 chr6 13872648 13872698 chr6 21178283 21178333 chr6 2139192921391979 chr6 27177635 27177685 chr6 27801900 27801950 chr6 2793574327935793 chr10 15172921 15172971 chr6 33695868 33695918 chr6 3536710335367153 chr6 35772061 35772111 chr6 36016047 36016097 chr6 4110309741103147 chr6 41462319 41462369 chr11 86629243 86629293 chr6 6430018964300239 chr6 66023691 66023741 chr6 68982595 68982645 chr6 6933446169334511 chr6 70306607 70306657 chr11 89874411 89874461 chr6 7402642374026473 chr11 91307903 91307953 chr6 108217708 108217758 chr6 115056135115056185 chr6 116842471 116842521 chr6 128076336 128076386 chr6139430899 139430949 chr6 163964464 163964514 chr6 164756639 164756689chr6 167307759 167307809 chr7 1613084 1613134 chr11 107707516 107707566chr7 4456539 4456589 chr7 5861127 5861177 chr7 25929316 25929366 chr726654295 26654345 chr7 35052296 35052346 chr7 35761667 35761717 chr738595062 38595112 chr7 54791547 54791597 chr7 56597365 56597415 chr765009545 65009595 chr7 71164829 71164879 chr7 72952260 72952310 chr782311705 82311755 chr7 92846028 92846078 chr7 97882914 97882964 chr799718424 99718474 chr7 105303415 105303465 chr7 105372233 105372283 chr7125051716 125051766 chr7 132326854 132326904 chr7 138782480 138782530chr7 139576426 139576476 chr7 139577352 139577402 chr7 147978484147978534 chr7 148137297 148137347 chr7 152822916 152822966 chr7153186761 153186811 chr7 153811053 153811103 chr7 156330857 156330907chr7 156360651 156360701 chr7 157189184 157189234 chr8 23599 23649 chr81914259 1914309 chr8 9101514 9101564 chr8 9654580 9654630 chr8 1004267410042724 chr8 13250066 13250116 chr8 15018941 15018991 chr11 122488344122488394 chr8 22974244 22974294 chr8 23239401 23239451 chr8 2864473128644781 chr8 30685352 30685402 chr8 34877997 34878047 chr8 3797805037978100 chr8 42914443 42914493 chr8 42917019 42917069 chr8 6044889060448940 chr11 125584444 125584494 chr8 65807715 65807765 chr8 6660263666602686 chr8 66920969 66921019 chr8 74797544 74797594 chr8 8973208289732132 chr8 90676737 90676787 chr8 95246983 95247033 chr8 9593691095936960 chr8 102444287 102444337 chr8 103586082 103586132 chr8119815714 119815764 chr8 127565096 127565146 chr8 128425710 128425760chr8 131516408 131516458 chr8 140383523 140383573 chr8 142227483142227533 chr8 142369390 142369440 chr8 142715550 142715600 chr8144357831 144357881 chr8 144423722 144423772 chr8 144423433 144423483chr8 145358253 145358303 chr9 483208 483258 chr9 1799869 1799919 chr92346635 2346685 chr9 6796826 6796876 chr11 132143103 132143153 chr912944109 12944159 chr9 17830955 17831005 chr9 20319218 20319268 chr938367567 38367617 chr9 38368829 38368879 chr9 72976522 72976572 chr977808855 77808905 chr9 85491422 85491472 chr9 86654526 86654576 chr991193443 91193493 chr9 94577013 94577063 chr9 96960735 96960785 chr9105259066 105259116 chr9 115990107 115990157 chr9 115991545 115991595chr12 1359635 1359685 chr9 124895644 124895694 chr9 126154431 126154481chr9 129105052 129105102 chr9 129995736 129995786 chr9 131297963131298013 chr9 133171727 133171777 chr9 133887157 133887207 chr126129080 6129130 chr12 6761610 6761660 chr12 7692419 7692469 chr128317135 8317185 chr12 25408389 25408439 chr12 29746873 29746923 chr1024988124 24988174 chr12 40959838 40959888 chr12 45056630 45056680 chr1245128295 45128345 chr12 47418403 47418453 chr12 50539003 50539053 chr1256968840 56968890 chr12 60986043 60986093 chr12 64837889 64837939 chr1267213853 67213903 chr12 75231144 75231194 chr12 78844699 78844749 chr1289693542 89693592 chr12 92860780 92860830 chr12 98170282 98170332 chr12101985034 101985084 chr12 103293857 103293907 chr12 107656363 107656413chr12 107816070 107816120 chr12 107815796 107815846 chr12 110249371110249421 chr12 113381681 113381731 chr12 115906409 115906459 chr12116927846 116927896 chr12 118258205 118258255 chr10 32625956 32626006chr12 121602372 121602422 chr12 124327960 124328010 chr10 3564706135647111 chr13 34067414 34067464 chr13 34068287 34068337 chr13 3763652437636574 chr13 43194669 43194719 chr13 47798908 47798958 chr13 4887034948870399 chr13 50416978 50417028 chr13 50497385 50497435 chr13 5813448258134532 chr13 58491566 58491616 chr13 64357981 64358031 chr13 6600460766004657 chr13 83519773 83519823 chr13 88837668 88837718 chr13 9469688594696935 chr13 96489160 96489210 chr13 111049333 111049383 chr13112203444 112203494 chr13 112208088 112208138 chr14 21317056 21317106chr14 32444317 32444367 chr14 35663309 35663359 chr14 42727447 42727497chr14 43806534 43806584 chr14 48832161 48832211 chr14 52829932 52829982chr14 53641855 53641905 chr14 57067371 57067421 chr14 59195724 59195774chr14 71096027 71096077 chr14 81288037 81288087 chr14 81538508 81538558chr14 82083942 82083992 chr14 83809998 83810048 chr14 93057642 93057692chr14 94345214 94345264 chr14 98772271 98772321 chr10 57963877 57963927chr14 100998909 100998959 chr14 103089988 103090038 chr15 2171204021712090 chr15 25987247 25987297 chr15 27093839 27093889 chr15 2785816427858214 chr15 29693425 29693475 chr15 30752514 30752564 chr15 3077138030771430 chr10 63292902 63292952 chr15 39044626 39044676 chr15 3917155639171606 chr15 43217726 43217776 chr15 48849597 48849647 chr15 4998572549985775 chr15 61025214 61025264 chr15 61151883 61151933 chr15 6324293063242980 chr15 63572807 63572857 chr15 69550711 69550761 chr15 7081662970816679 chr15 73861885 73861935 chr15 75647642 75647692 chr15 8363884583638895 chr15 85494079 85494129 chr15 87793860 87793910 chr15 8821444188214491 chr15 88622338 88622388 chr10 69759189 69759239 chr15 9465429494654344 chr15 97230038 97230088 chr10 70104088 70104138 chr16 226967227017 chr16 1027708 1027758 chr16 1027451 1027501 chr16 2391658 2391708chr16 2406338 2406388 chr16 2725773 2725823 chr16 3180386 3180436 chr164696365 4696415 chr16 5535686 5535736 chr16 5879045 5879095 chr167007810 7007860 chr16 9131602 9131652 chr16 9460990 9461040 chr1610427595 10427645 chr16 10586268 10586318 chr16 10858574 10858624 chr1611915889 11915939 chr16 12436426 12436476 chr16 23522525 23522575 chr1629966171 29966221 chr16 29966305 29966355 chr16 31103357 31103407 chr1631149141 31149191 chr16 46656260 46656310 chr16 46662249 46662299 chr1656411872 56411922 chr16 58081119 58081169 chr16 60113353 60113403 chr1662140586 62140636 chr16 63155437 63155487 chr16 65500059 65500109 chr1666912749 66912799 chr16 68404424 68404474 chr16 69314198 69314248 chr1073953280 73953330 chr16 75212195 75212245 chr16 76723118 76723168 chr1680441908 80441958 chr16 80441609 80441659 chr16 85095814 85095864 chr1685215597 85215647 chr16 87107657 87107707 chr16 87107326 87107376 chr1687652684 87652734 chr16 89140641 89140691 chr16 89312607 89312657 chr1689671823 89671873 chr17 307644 307694 chr17 309190 309240 chr10 7630754276307592 chr17 3726180 3726230 chr17 4754733 4754783 chr17 62796726279722 chr17 6280400 6280450 chr17 8820911 8820961 chr17 1009425110094301 chr17 11533046 11533096 chr17 14948401 14948451 chr17 1552959415529644 chr17 16562294 16562344 chr17 17547553 17547603 chr17 3218505932185109 Table 15DF. Repeat Category MLT1F1 chr17 47838548 47838598chr17 59104693 59104743 chr17 75164482 75164532 chr10 92621546 92621596chr17 80621480 80621530 chr10 95796346 95796396 chr18 36675429 36675479chr18 42028491 42028541 chr18 58631226 58631276 chr18 73817063 73817113chr19 463625 463675 chr19 2317879 2317929 chr19 2611249 2611299 chr10101648692 101648742 chr19 12795021 12795071 chr10 107983467 107983517chr19 51772260 51772310 chr19 51772894 51772944 chr19 60415782 60415832chr19 63568373 63568423 chr10 116031715 116031765 chr1 7633036 7633086chr1 9450768 9450818 chr1 23571768 23571818 chr1 24369619 24369669 chr125784989 25785039 chr10 120555242 120555292 chr1 63144111 63144161 chr10127655663 127655713 chr1 187254490 187254540 chr1 228974382 228974432chr20 296177 296227 chr20 5615696 5615746 chr20 5938312 5938362 chr10133069071 133069121 chr20 20389642 20389692 chr10 133624391 133624441chr20 36653150 36653200 chr20 40223237 40223287 chr20 43584565 43584615chr20 55595415 55595465 chr20 62346837 62346887 chr21 15939883 15939933chr21 44121637 44121687 chr21 44215130 44215180 chr22 29865663 29865713chr22 40138192 40138242 chr22 41803769 41803819 chr22 48075796 48075846chr22 48305361 48305411 chrX 14177519 14177569 chrX 17142311 17142361chrX 23841302 23841352 chrX 39950710 39950760 chrX 42487008 42487058chrX 45576963 45577013 chrX 47905550 47905600 chrX 68240643 68240693chrX 75982250 75982300 chrX 99473450 99473500 chrX 151740030 151740080chrX 152532071 152532121 chr2 32434102 32434152 chr2 48815338 48815388chr2 53861149 53861199 chr2 74335998 74336048 chr2 78773086 78773136chr2 86900893 86900943 chr2 113111019 113111069 chr2 129216610 129216660chr2 160006282 160006332 chr2 170765919 170765969 chr2 200971337200971387 chr2 216166647 216166697 chr2 220207353 220207403 chr2220207448 220207498 chr2 234434348 234434398 chr2 238054837 238054887chr2 239331752 239331802 chr3 9559873 9559923 chr3 26379414 26379464chr3 46010834 46010884 chr3 61224280 61224330 chr3 68984356 68984406chr3 68984421 68984471 chr3 107499192 107499242 chr3 110461564 110461614chr3 112627691 112627741 chr3 125582950 125583000 chr3 128911181128911231 chr3 162076618 162076668 chr11 62987799 62987849 chr3193877524 193877574 chr4 1613199 1613249 chr4 7780612 7780662 chr425454091 25454141 chr4 84283546 84283596 chr4 96101259 96101309 chr4107045807 107045857 chr4 115231995 115232045 chr4 121540640 121540690chr4 129056103 129056153 chr4 130092495 130092545 chr4 133391388133391438 chr11 67089836 67089886 chr4 161477188 161477238 chr4175532466 175532516 chr4 178080590 178080640 chr4 190254153 190254203chr5 1014793 1014843 chr5 6075012 6075062 chr5 32222282 32222332 chr553794012 53794062 chr5 58180120 58180170 chr5 74061942 74061992 chr574917467 74917517 chr5 76501677 76501727 chr5 85513802 85513852 chr5103113882 103113932 chr5 112068206 112068256 chr5 132426356 132426406chr5 138132013 138132063 chr5 138199022 138199072 chr5 138668032138668082 chr5 139488762 139488812 chr5 139501048 139501098 chr5141459637 141459687 chr5 172965556 172965606 chr5 174626794 174626844chr5 175327127 175327177 chr5 176483897 176483947 chr5 180689794180689844 chr11 86629243 86629293 chr6 70306607 70306657 chr6 7402642374026473 chr11 91307903 91307953 chr6 115056135 115056185 chr6 116842471116842521 chr11 107707516 107707566 chr7 38595062 38595112 chr7 6500954565009595 chr7 71164829 71164879 chr7 82311705 82311755 chr7 105303415105303465 chr7 125051716 125051766 chr7 139576426 139576476 chr7139577352 139577402 chr7 156330857 156330907 chr7 157189184 157189234chr8 23599 23649 chr11 122488344 122488394 chr8 30685352 30685402 chr8127565096 127565146 chr8 144423722 144423772 chr8 144423433 144423483chr9 1799869 1799919 chr9 6796826 6796876 chr9 12944109 12944159 chr9129105052 129105102 chr9 129995736 129995786 chr9 133171727 133171777chr9 133887157 133887207 chr12 47418403 47418453 chr12 50539003 50539053chr12 92860780 92860830 chr12 110249371 110249421 chr12 116927846116927896 chr10 32625956 32626006 chr12 121602372 121602422 chr12124327960 124328010 chr13 88837668 88837718 chr14 48832161 48832211chr14 81538508 81538558 chr14 82083942 82083992 chr14 93057642 93057692chr14 94345214 94345264 chr14 98772271 98772321 chr14 100998909100998959 chr15 27858164 27858214 chr15 30752514 30752564 chr10 6329290263292952 chr15 39171556 39171606 chr15 43217726 43217776 chr15 6324293063242980 chr15 69550711 69550761 chr10 69759189 69759239 chr15 9465429494654344 chr16 226967 227017 chr16 1027708 1027758 chr16 1027451 1027501chr16 10586268 10586318 chr16 11915889 11915939 chr16 46656260 46656310chr16 46662249 46662299 chr16 58081119 58081169 chr16 66912749 66912799chr16 85095814 85095864 chr16 87652684 87652734 chr16 89140641 89140691chr16 89671823 89671873 chr10 76307542 76307592 chr17 8820911 8820961chr17 15529594 15529644 chr17 16562294 16562344 Table 15DG. RepeatCategory MLT1G1 chr17 58954765 58954815 chr10 86187299 86187349 chr1772717269 72717319 chr17 75547923 75547973 chr17 75595937 75595987 chr1777557056 77557106 chr18 11547510 11547560 chr10 95129757 95129807 chr1095413321 95413371 chr18 23406852 23406902 chr18 36866944 36866994 chr1097933975 97934025 chr18 69075067 69075117 chr18 69794363 69794413 chr1873331526 73331576 chr18 73331270 73331320 chr10 100251131 100251181chr19 2838149 2838199 chr10 101102945 101102995 chr19 6848179 6848229chr19 6847789 6847839 chr19 15530607 15530657 chr19 44208004 44208054chr19 45216299 45216349 chr19 45510386 45510436 chr19 45848729 45848779chr19 46645050 46645100 chr19 53719229 53719279 chr1 9956135 9956185chr1 9958461 9958511 chr1 10973375 10973425 chr1 22117570 22117620 chr124890233 24890283 chr1 32673587 32673637 chr1 38485694 38485744 chr140198973 40199023 chr1 40933098 40933148 chr1 57315426 57315476 chr163063337 63063387 chr1 63063549 63063599 chr1 63063932 63063982 chr163064161 63064211 chr1 93723638 93723688 chr1 158073478 158073528 chr1167406656 167406706 chr1 167407601 167407651 chr1 179318425 179318475chr1 226348786 226348836 chr1 244068010 244068060 chr20 2005208020052130 chr20 20051962 20052012 chr20 24784053 24784103 chr20 2489403024894080 chr20 34373693 34373743 chr20 58189827 58189877 chr20 5950766759507717 chr20 62346837 62346887 chr20 62749255 62749305 chr21 2147420021474250 chr21 21473974 21474024 chr21 26165546 26165596 chr21 3189052931890579 chr21 34834766 34834816 chr21 39706626 39706676 chr21 4033479140334841 chr21 45349143 45349193 chr21 46113059 46113109 chr21 4611365946113709 chr22 24767594 24767644 chr22 36789048 36789098 chr22 3687315836873208 chr11 2561822 2561872 chr11 2863193 2863243 chrX 1779616717796217 chrX 21713834 21713884 chrX 23194469 23194519 chrX 3887347438873524 chr11 8654721 8654771 chr2 645217 645267 chr2 7194792 7194842chr2 8864628 8864678 chr2 15233171 15233221 chr2 16048807 16048857 chr219652981 19653031 chr2 25837239 25837289 chr2 41526171 41526221 chr269866988 69867038 chr2 75799728 75799778 chr2 112051140 112051190 chr2113784854 113784904 chr2 120666259 120666309 chr2 159225768 159225818chr2 159225520 159225570 chr2 208574556 208574606 chr2 215958477215958527 chr2 233696531 233696581 chr2 236326913 236326963 chr3 65876836587733 chr3 14902067 14902117 chr3 15362495 15362545 chr3 2033264620332696 chr3 39173219 39173269 chr3 46010834 46010884 chr3 5161204151612091 chr3 78193364 78193414 chr3 100845901 100845951 chr3 100845236100845286 chr3 126257021 126257071 chr3 127097883 127097933 chr3141758515 141758565 chr3 166958907 166958957 chr4 6734614 6734664 chr47659924 7659974 chr4 19466589 19466639 chr4 29850644 29850694 chr437615942 37615992 chr4 37618923 37618973 chr4 40841592 40841642 chr444492212 44492262 chr4 57767143 57767193 chr4 89326161 89326211 chr4102210187 102210237 chr4 110061801 110061851 chr4 141088996 141089046chr4 144598972 144599022 chr4 157281132 157281182 chr4 161645228161645278 chr4 166237474 166237524 chr4 171564258 171564308 chr4191071761 191071811 chr5 6075254 6075304 chr5 6075012 6075062 chr56437024 6437074 chr5 10171631 10171681 chr5 25452937 25452987 chr537802862 37802912 chr5 38265439 38265489 chr5 56464643 56464693 chr578591185 78591235 chr5 81327129 81327179 chr5 103818213 103818263 chr1171889108 71889158 chr10 14521697 14521747 chr5 132010239 132010289 chr5143589416 143589466 chr5 157379428 157379478 chr5 163762160 163762210chr5 163761885 163761935 chr5 169800405 169800455 chr5 173790037173790087 chr5 177776936 177776986 chr6 24846609 24846659 chr6 2741720427417254 chr11 84450242 84450292 chr6 49482828 49482878 chr11 8901064089010690 chr6 82773885 82773935 chr6 93542478 93542528 chr6 133187616133187666 chr10 15808906 15808956 chr11 105157151 105157201 chr6170573016 170573066 chr6 170572746 170572796 chr6 170573098 170573148chr7 764166 764216 chr7 764361 764411 chr7 1304506 1304556 chr7 24994632499513 chr7 2499279 2499329 chr7 2782798 2782848 chr7 4195740 4195790chr7 4363467 4363517 chr7 22144728 22144778 chr7 47271517 47271567 chr747271430 47271480 chr7 55588403 55588453 chr7 99220910 99220960 chr7129353402 129353452 chr7 138549900 138549950 chr7 145539469 145539519chr11 121297297 121297347 chr8 17139164 17139214 chr8 17702176 17702226chr8 88865698 88865748 chr11 128156948 128156998 chr8 103212414103212464 chr8 103212500 103212550 chr8 109971604 109971654 chr8140647303 140647353 chr9 3469781 3469831 chr9 12259100 12259150 chr933161868 33161918 chr11 133223176 133223226 chr11 133222861 133222911chr9 74567171 74567221 chr9 86380195 86380245 chr9 93738245 93738295chr9 110920241 110920291 chr9 133382001 133382051 chr9 133383010133383060 chr10 22500800 22500850 chr12 15801880 15801930 chr12 2724897927249029 chr12 47592583 47592633 chr12 84275159 84275209 chr10 2941691129416961 chr12 88239050 88239100 chr12 111249132 111249182 chr12112566569 112566619 chr12 112913349 112913399 chr12 113927157 113927207chr12 113926953 113927003 chr12 115418466 115418516 chr12 122348956122349006 chr13 70313039 70313089 chr13 71014871 71014921 chr13 8597662285976672 chr13 101221176 101221226 chr13 101221110 101221160 chr1421259955 21260005 chr14 56853950 56854000 chr14 57949844 57949894 chr1472057569 72057619 chr14 74616673 74616723 chr14 89708039 89708089 chr14101217495 101217545 chr14 102073153 102073203 chr14 103096635 103096685chr15 25950421 25950471 chr15 35413729 35413779 chr10 69359082 69359132chr15 99815043 99815093 chr16 16794897 16794947 chr16 18602324 18602374chr16 51408954 51409004 chr10 73899939 73899989 chr16 75212195 75212245chr16 85517429 85517479 chr16 86447566 86447616 chr16 86596769 86596819chr16 88258867 88258917 chr16 89513481 89513531 chr17 540372 540422chr17 7969867 7969917 chr17 16863762 16863812 chr17 19176037 19176087chr17 36058731 36058781 Table 15DH. Repeat Category MLT2A2 chr1751756645 51756695 chr17 61506008 61506058 chr17 68455881 68455931 chr1838016939 38016989 chr18 38016466 38016516 chr18 42958118 42958168 chr1098244194 98244244 chr18 67484894 67484944 chr10 106907327 106907377chr19 51405439 51405489 chr19 51405283 51405333 chr19 59443366 59443416chr1 3909422 3909472 chr1 8906545 8906595 chr1 9279370 9279420 chr19297577 9297627 chr1 12273663 12273713 chr1 63073556 63073606 chr188529129 88529179 chr1 96184470 96184520 chr10 6825607 6825657 chr106825186 6825236 chr10 125859633 125859683 chr1 192561402 192561452 chr10131335709 131335759 chr20 47842721 47842771 chr21 20737501 20737551chr21 28595088 28595138 chr21 29145010 29145060 chr21 46615321 46615371chr22 15312379 15312429 chrX 4764063 4764113 chrX 6372101 6372151 chrX17784709 17784759 chrX 19416489 19416539 chrX 88082370 88082420 chrX101263683 101263733 chrX 114708023 114708073 chrY 3305969 3306019 chr25087716 5087766 chr2 6982850 6982900 chr11 18195154 18195204 chr1118194906 18194956 chr11 18440395 18440445 chr2 37866238 37866288 chr1120553729 20553779 chr2 56825740 56825790 chr11 27753445 27753495 chr2103118135 103118185 chr2 133559628 133559678 chr11 33932843 33932893chr2 170920350 170920400 chr2 199607850 199607900 chr2 203969901203969951 chr2 224369830 224369880 chr2 224937948 224937998 chr314998439 14998489 chr3 34725721 34725771 chr3 35621701 35621751 chr368470120 68470170 chr3 74516329 74516379 chr3 77645541 77645591 chr3105605117 105605167 chr3 106151957 106152007 chr3 109781633 109781683chr3 169820168 169820218 chr3 194057014 194057064 chr4 32868244 32868294chr4 34107951 34108001 chr4 59153299 59153349 chr4 89912622 89912672chr4 117018984 117019034 chr4 132678146 132678196 chr4 140941457140941507 chr4 161611356 161611406 chr4 175466338 175466388 chr5 20334202033470 chr5 2278185 2278235 chr5 6932896 6932946 chr5 22684338 22684388chr5 26747254 26747304 chr11 69718886 69718936 chr5 44985597 44985647chr5 64798423 64798473 chr5 121540580 121540630 chr5 122382726 122382776chr5 162323487 162323537 chr6 11889422 11889472 chr6 50961577 50961627chr11 90082072 90082122 chr6 103252161 103252211 chr6 105710211105710261 chr11 97450060 97450110 chr6 146569176 146569226 chr6148129775 148129825 chr11 104666946 104666996 chr7 69914072 69914122chr7 69916233 69916283 chr7 104622716 104622766 chr7 110266516 110266566chr7 115481261 115481311 chr7 135292474 135292524 chr8 2131193 2131243chr8 14347269 14347319 chr8 40224296 40224346 chr9 12371070 12371120chr9 20815899 20815949 chr9 20815816 20815866 chr9 113485125 113485175chr12 3744503 3744553 chr12 54946744 54946794 chr12 56236684 56236734chr12 59251633 59251683 chr12 104506203 104506253 chr12 106314005106314055 chr12 111435179 111435229 chr12 125835508 125835558 chr1034899259 34899309 chr10 42034027 42034077 chr13 52661975 52662025 chr13103856039 103856089 chr13 103855841 103855891 chr14 59622519 59622569chr14 60513579 60513629 chr14 69842721 69842771 chr14 93626408 93626458chr14 100353991 100354041 chr14 102525042 102525092 chr14 104932537104932587 chr15 22839882 22839932 chr15 37820735 37820785 chr15 8171432881714378 chr16 13494592 13494642 chr16 89134294 89134344 chr17 42302594230309 chr17 21179866 21179916 Table 15DI. Repeat Category MLT2B1 chr1764813207 64813257 chr18 869566 869616 chr18 12891931 12891981 chr1816993075 16993125 chr18 46624091 46624141 chr18 68910954 68911004 chr1871015702 71015752 chr18 74481918 74481968 chr19 14296119 14296169 chr1918793111 18793161 chr19 45408107 45408157 chr19 59274379 59274429 chr1960674467 60674517 chr1 9294515 9294565 chr1 11154981 11155031 chr123626682 23626732 chr1 39483892 39483942 chr1 49242874 49242924 chr1119973468 119973518 chr10 7537343 7537393 chr1 240975151 240975201 chr1241508439 241508489 chr1 246005048 246005098 chr20 2154318 2154368 chr2011372729 11372779 chr20 38742153 38742203 chr20 46773608 46773658 chr2125200111 25200161 chr21 33118597 33118647 chr21 43747724 43747774 chr2143747504 43747554 chr11 1601856 1601906 chr22 34302719 34302769 chr2239381226 39381276 chr22 42710174 42710224 chr22 45935208 45935258 chr2246239906 46239956 chr22 46239663 46239713 chr22 47538539 47538589 chr2247913364 47913414 chrX 29879581 29879631 chrX 29905010 29905060 chrX30730952 30731002 chrX 117591018 117591068 chrY 6144298 6144348 chr222843654 22843704 chr2 43092909 43092959 chr2 62475076 62475126 chr278874346 78874396 chr2 79584169 79584219 chr2 137666784 137666834 chr2155679366 155679416 chr2 175333644 175333694 chr2 203754217 203754267chr2 206946511 206946561 chr2 237602498 237602548 chr2 241947266241947316 chr3 15149900 15149950 chr3 16362141 16362191 chr11 4907074149070791 chr3 71859392 71859442 chr11 58237769 58237819 chr3 124459135124459185 chr3 124458995 124459045 chr3 156037804 156037854 chr3174491165 174491215 chr11 63109115 63109165 chr4 8743364 8743414 chr436868320 36868370 chr4 39562913 39562963 chr4 42159278 42159328 chr445511568 45511618 chr11 65250440 65250490 chr4 91637694 91637744 chr4110633745 110633795 chr4 111594382 111594432 chr4 127195479 127195529chr4 166297456 166297506 chr10 13816303 13816353 chr10 13816183 13816233chr5 8807918 8807968 chr5 21573722 21573772 chr5 25938550 25938600 chr539712614 39712664 chr5 61431233 61431283 chr5 86612830 86612880 chr586612658 86612708 chr11 72688134 72688184 chr10 14745869 14745919 chr5172981585 172981635 chr6 10966242 10966292 chr11 80242000 80242050 chr628705039 28705089 chr11 89172265 89172315 chr6 71296452 71296502 chr6105747608 105747658 chr6 124874258 124874308 chr6 131861203 131861253chr6 154870278 154870328 chr6 169731254 169731304 chr7 3976774 3976824chr7 4437466 4437516 chr7 8619853 8619903 chr7 15486372 15486422 chr716314666 16314716 chr7 16314370 16314420 chr7 37398535 37398585 chr746434126 46434176 chr7 64486710 64486760 chr7 97275229 97275279 chr7122760060 122760110 chr7 126106333 126106383 chr7 134818844 134818894chr7 155240895 155240945 chr7 156341430 156341480 chr7 157819504157819554 chr8 222053 222103 chr8 12446641 12446691 chr8 2350811523508165 chr8 26975212 26975262 chr8 52607316 52607366 chr8 8305288183052931 chr8 103450798 103450848 chr8 137520868 137520918 chr9 1533808515338135 chr9 42639813 42639863 chr9 76603008 76603058 chr9 126685267126685317 chr9 132082816 132082866 chr9 132625264 132625314 chr9132894599 132894649 chr9 133596915 133596965 chr9 133711537 133711587chr12 13420931 13420981 chr12 13420842 13420892 chr12 15213662 15213712chr12 15213390 15213440 chr12 54160277 54160327 chr12 56358586 56358636chr12 88184808 88184858 chr12 89198972 89199022 chr12 100586100100586150 chr12 127686575 127686625 chr12 128413797 128413847 chr1036009656 36009706 chr13 25407090 25407140 chr13 42788680 42788730 chr1358036223 58036273 chr14 19013552 19013602 chr14 19595168 19595218 chr1436898760 36898810 chr14 57623612 57623662 chr14 72323518 72323568 chr1481120912 81120962 chr10 57552657 57552707 chr15 21261738 21261788 chr1591737448 91737498 chr15 92194416 92194466 chr16 11247497 11247547 chr1612114668 12114718 chr16 19805588 19805638 chr16 20900756 20900806 chr1649584112 49584162 chr16 50630494 50630544 chr16 54982509 54982559 chr1684011623 84011673 chr16 84011832 84011882 chr17 15114820 15114870 chr1726902719 26902769 Table 15DJ. Repeat Category MLT2B2 chr17 4232415242324202 chr17 51513647 51513697 chr18 2472063 2472113 chr18 4702510847025158 chr19 1842578 1842628 chr19 5913243 5913293 chr1 2552082325520873 chr1 40216538 40216588 chr1 103974751 103974801 chr1 164040876164040926 chr1 183918698 183918748 chr1 192085481 192085531 chr10131824919 131824969 chr10 132134256 132134306 chr1 244499146 244499196chr20 4985317 4985367 chr20 22127357 22127407 chr20 40945275 40945325chr20 55952755 55952805 chr21 18211675 18211725 chr21 18211411 18211461chr21 22863933 22863983 chr22 47519185 47519235 chrX 17859254 17859304chrX 43622446 43622496 chrX 44176902 44176952 chrX 98507925 98507975chrX 110257160 110257210 chrY 7125685 7125735 chr2 8444248 8444298 chr230501804 30501854 chr2 53958434 53958484 chr2 116810202 116810252 chr2153280475 153280525 chr2 186283894 186283944 chr2 204295646 204295696chr2 228727285 228727335 chr2 240711975 240712025 chr3 53270082 53270132chr3 108288719 108288769 chr3 108288519 108288569 chr3 128217716128217766 chr3 145865320 145865370 chr3 185450976 185451026 chr4 56929635693013 chr11 65213837 65213887 chr11 65214358 65214408 chr4 153633265153633315 chr4 184964214 184964264 chr4 184964334 184964384 chr4184965109 184965159 chr4 185184983 185185033 chr4 188898341 188898391chr5 14169093 14169143 chr5 76757706 76757756 chr5 130647790 130647840chr5 131229208 131229258 chr5 131772240 131772290 chr5 176388024176388074 chr6 21096792 21096842 chr11 89124528 89124578 chr6 137411784137411834 chr7 47366209 47366259 chr7 47457236 47457286 chr11 114462889114462939 chr10 17433699 17433749 chr8 2760276 2760326 chr11 122277054122277104 chr8 93178573 93178623 chr8 142540071 142540121 chr8 142971896142971946 chr9 38880245 38880295 chr9 73935023 73935073 chr9 105476092105476142 chr9 105476006 105476056 chr12 82119256 82119306 chr12103065833 103065883 chr12 125529778 125529828 chr10 44089462 44089512chr10 44089692 44089742 chr14 85015790 85015840 chr14 103100312103100362 chr16 10300759 10300809 chr16 16906758 16906808 chr16 2748935727489407 chr16 60377051 60377101 chr16 68431780 68431830 chr17 1392327713923327 chr17 26927387 26927437 chr17 27276932 27276982 chr10 37375543737604 Table 15DK. Repeat Category MLT2B3 chr17 49888862 49888912 chr1095264677 95264727 chr18 22041995 22042045 chr18 37083225 37083275 chr1842490825 42490875 chr10 97590744 97590794 chr18 66218240 66218290 chr1868944895 68944945 chr19 47728580 47728630 chr19 47729535 47729585 chr1953255201 53255251 chr10 112854925 112854975 chr19 59648218 59648268 chr113155265 13155315 chr1 19095012 19095062 chr1 23845639 23845689 chr131977074 31977124 chr1 35144722 35144772 chr1 36134155 36134205 chr149757364 49757414 chr1 91068049 91068099 chr1 91068263 91068313 chr191068479 91068529 chr1 91068828 91068878 chr1 108845441 108845491 chr1118919477 118919527 chr1 140876147 140876197 chr10 127045012 127045062chr1 212251208 212251258 chr1 220036870 220036920 chr1 221999851221999901 chr21 26101449 26101499 chr22 39303942 39303992 chrX 75457247545774 chrX 24901828 24901878 chrX 79745570 79745620 chrX 8109260281092652 chrX 88483053 88483103 chrX 91309953 91310003 chrX 9291901592919065 chrX 101263683 101263733 chrX 137506868 137506918 chr2 924683924733 chr2 15066592 15066642 chr2 77632501 77632551 chr2 123251438123251488 chr2 144889273 144889323 chr2 166290295 166290345 chr2168884380 168884430 chr3 42586294 42586344 chr11 54806468 54806518 chr3107690373 107690423 chr3 110614107 110614157 chr3 141881935 141881985chr3 154031575 154031625 chr3 166336650 166336700 chr3 192959356192959406 chr4 6375852 6375902 chr11 64045589 64045639 chr4 1321112913211179 chr4 61366061 61366111 chr4 95536618 95536668 chr4 129845885129845935 chr4 142706241 142706291 chr4 166625966 166626016 chr4184645832 184645882 chr4 186824022 186824072 chr5 39494380 39494430 chr545884691 45884741 chr5 52695082 52695132 chr11 70609329 70609379 chr589693137 89693187 chr5 100625253 100625303 chr6 10101594 10101644 chr621762273 21762323 chr6 38123665 38123715 chr6 68839330 68839380 chr680963036 80963086 chr6 116131504 116131554 chr6 122458270 122458320 chr6137411784 137411834 chr11 99456629 99456679 chr7 1304506 1304556 chr719029198 19029248 chr7 19030908 19030958 chr7 42251464 42251514 chr753621070 53621120 chr7 53621388 53621438 chr7 109931413 109931463 chr7110694806 110694856 chr7 146878109 146878159 chr7 149081470 149081520chr7 153192272 153192322 chr7 158362589 158362639 chr8 6059943 6059993chr8 13012225 13012275 chr8 14814171 14814221 chr8 30115657 30115707chr8 30115580 30115630 chr8 33100860 33100910 chr8 38099130 38099180chr8 40224296 40224346 chr8 103101496 103101546 chr8 122699189 122699239chr8 127765825 127765875 chr8 141051202 141051252 chr9 14832661 14832711chr9 28426844 28426894 chr9 33189448 33189498 chr9 36552123 36552173chr9 36552755 36552805 chr9 85511805 85511855 chr11 134289347 134289397chr9 126998275 126998325 chr9 126998807 126998857 chr9 132024899132024949 chr9 132141966 132142016 chr9 132317874 132317924 chr1210469448 10469498 chr12 22979813 22979863 chr13 82836075 82836125 chr1433286669 33286719 chr15 21774081 21774131 chr15 62393346 62393396 chr16799691 799741 chr16 19258937 19258987 chr16 57302318 57302368 chr1658064548 58064598 chr16 73715126 73715176 chr17 279849 279899 chr178157601 8157651 chr17 28244775 28244825 Table 15DL. Repeat CategoryMLT2B4 chr17 76057738 76057788 chr17 76114760 76114810 chr17 7611688376116933 chr18 3619827 3619877 chr18 75730292 75730342 chr19 5470561554705665 chr10 118349143 118349193 chr1 21217328 21217378 chr1 6225322062253270 chr1 82052362 82052412 chr10 6800392 6800442 chr1 152351055152351105 chr1 162047623 162047673 chr1 175962612 175962662 chr1190665709 190665759 chr1 242419138 242419188 chr20 3748977 3749027 chr2036103118 36103168 chr20 38390453 38390503 chr20 47209101 47209151 chr2047212140 47212190 chr20 47211823 47211873 chr20 47435851 47435901 chr2047785934 47785984 chr20 47787367 47787417 chr20 47818208 47818258 chr2117922576 17922626 chr21 22016893 22016943 chr21 31741048 31741098 chr2140782219 40782269 chr22 35432316 35432366 chr22 39935942 39935992 chr2241077304 41077354 chr22 41153900 41153950 chr22 41155029 41155079 chr2241326511 41326561 chr22 43633345 43633395 chr22 44532882 44532932 chrX3066239 3066289 chrX 3166567 3166617 chrX 22501900 22501950 chrX33526748 33526798 chrX 105389184 105389234 chrX 111031038 111031088 chrX116934192 116934242 chrX 132790269 132790319 chrX 143266890 143266940chr2 10591259 10591309 chr2 10592453 10592503 chr2 13743753 13743803chr2 15246971 15247021 chr2 32519841 32519891 chr2 47480090 47480140chr2 55955226 55955276 chr2 72599467 72599517 chr2 112160061 112160111chr11 33932843 33932893 chr2 147000420 147000470 chr2 157253723157253773 chr2 164844199 164844249 chr2 188936364 188936414 chr2225686623 225686673 chr2 241364100 241364150 chr2 243279464 243279514chr11 47416833 47416883 chr3 23289221 23289271 chr3 27557442 27557492chr3 35492659 35492709 chr3 44435106 44435156 chr3 50997473 50997523chr11 57543049 57543099 chr3 85318069 85318119 chr10 12792749 12792799chr3 171420074 171420124 chr3 176609269 176609319 chr3 178342233178342283 chr3 190403197 190403247 chr3 196995464 196995514 chr3197057427 197057477 chr3 198694503 198694553 chr4 1289256 1289306 chr43746624 3746674 chr4 25706985 25707035 chr4 36361613 36361663 chr446066583 46066633 chr4 55291213 55291263 chr4 77238673 77238723 chr4116308807 116308857 chr4 185942047 185942097 chr4 189810150 189810200chr4 191279911 191279961 chr5 1650636 1650686 chr5 1674289 1674339 chr51676869 1676919 chr5 3083945 3083995 chr5 25462370 25462420 chr526271413 26271463 chr5 26513753 26513803 chr5 29831786 29831836 chr530475097 30475147 chr5 43295268 43295318 chr5 76167067 76167117 chr611426770 11426820 chr6 11426577 11426627 chr6 52404923 52404973 chr652404817 52404867 chr6 76257273 76257323 chr6 150407323 150407373 chr6158814989 158815039 chr6 166014491 166014541 chr6 166881545 166881595chr6 166881337 166881387 chr6 170021365 170021415 chr7 2202097 2202147chr11 113272824 113272874 chr11 113424814 113424864 chr7 7180380571803855 chr7 92643844 92643894 chr7 97753959 97754009 chr7 9852880398528853 chr7 106529957 106530007 chr7 122760060 122760110 chr7146323510 146323560 chr8 6144762 6144812 chr8 10166911 10166961 chr810435924 10435974 chr8 25001794 25001844 chr8 80272702 80272752 chr883052881 83052931 chr8 86221696 86221746 chr8 103410341 103410391 chr976833828 76833878 chr9 85826471 85826521 chr9 90786194 90786244 chr995938036 95938086 chr9 104862008 104862058 chr9 112452670 112452720 chr9122764946 122764996 chr9 132580615 132580665 chr9 134472238 134472288chr9 134744747 134744797 chr12 31688673 31688723 chr12 47580608 47580658chr12 84515765 84515815 chr12 88670035 88670085 chr12 94981437 94981487chr12 128132968 128133018 chr13 28122798 28122848 chr13 109462661109462711 chr14 79478772 79478822 chr14 81560030 81560080 chr14 9463751594637565 chr16 3248889 3248939 chr16 65166885 65166935 chr16 7437389674373946 chr16 87615363 87615413 chr17 29059554 29059604 Table 15DM.Repeat Category MLT2D chr17 42892627 42892677 chr17 72581475 72581525chr18 20271821 20271871 chr18 26386186 26386236 chr18 35294094 35294144chr18 69101334 69101384 chr19 6508751 6508801 chr19 38948511 38948561chr19 52619852 52619902 chr19 59238897 59238947 chr1 1792237 1792287chr1 2732525 2732575 chr1 3891642 3891692 chr1 5614386 5614436 chr17106875 7106925 chr1 7675012 7675062 chr1 13374220 13374270 chr115202424 15202474 chr1 30646775 30646825 chr1 64425593 64425643 chr166660569 66660619 chr1 82896747 82896797 chr1 93434106 93434156 chr1100673040 100673090 chr1 190665709 190665759 chr1 226702304 226702354chr1 230815266 230815316 chr10 131932323 131932373 chr1 238027964238028014 chr1 244446259 244446309 chr20 13668055 13668105 chr2017789508 17789558 chr20 34412449 34412499 chr20 35953103 35953153 chr10133682067 133682117 chr20 36391236 36391286 chr20 41754886 41754936chr20 55956411 55956461 chr20 60658952 60659002 chr11 249897 249947chr21 25959866 25959916 chr21 44755927 44755977 chr22 21274136 21274186chr22 23908895 23908945 chr22 23910026 23910076 chr22 44201421 44201471chr22 46242729 46242779 chrX 3066239 3066289 chrX 23495332 23495382 chrX40216681 40216731 chrX 51816777 51816827 chrX 54640989 54641039 chrX88476179 88476229 chrX 132294706 132294756 chrX 132432650 132432700 chr22937024 2937074 chr2 48354622 48354672 chr2 75011422 75011472 chr278359108 78359158 chr2 103118135 103118185 chr2 113005174 113005224 chr2113004961 113005011 chr2 113005822 113005872 chr11 37232568 37232618chr2 186420932 186420982 chr2 231303416 231303466 chr11 4536461945364669 chr2 243020202 243020252 chr3 636641 636691 chr3 32593203259370 chr3 15304330 15304380 chr3 15304177 15304227 chr3 4416838644168436 chr3 57058513 57058563 chr3 128580101 128580151 chr3 128580276128580326 chr3 131539530 131539580 chr3 136092810 136092860 chr3139961212 139961262 chr3 191789601 191789651 chr4 3775205 3775255 chr46173853 6173903 chr4 7213137 7213187 chr4 7221949 7221999 chr11 6470421064704260 chr4 42112098 42112148 chr4 46918627 46918677 chr4 8900672789006777 chr4 98350549 98350599 chr4 99692300 99692350 chr4 132131127132131177 chr11 67099473 67099523 chr4 160408961 160409011 chr4185228517 185228567 chr4 185229918 185229968 chr4 186620823 186620873chr5 17989253 17989303 chr5 22805974 22806024 chr5 76360250 76360300chr5 95127318 95127368 chr5 121895650 121895700 chr5 141434767 141434817chr5 168028580 168028630 chr5 170150488 170150538 chr5 173936851173936901 chr6 19892444 19892494 chr6 27815049 27815099 chr6 3983318339833233 chr6 42654824 42654874 chr10 15290849 15290899 chr6 115011254115011304 chr6 147835252 147835302 chr11 101258719 101258769 chr6158814989 158815039 chr6 168228942 168228992 chr6 168842830 168842880chr7 10645580 10645630 chr7 12517848 12517898 chr7 55217291 55217341chr7 69839805 69839855 chr11 118353449 118353499 chr7 130765665130765715 chr7 131615325 131615375 chr7 134360358 134360408 chr7148487590 148487640 chr7 150977859 150977909 chr7 153386640 153386690chr8 9425976 9426026 chr8 26301614 26301664 chr8 42495133 42495183 chr852623676 52623726 chr8 139920986 139921036 chr8 144352829 144352879 chr916134469 16134519 chr9 67714503 67714553 chr9 94830443 94830493 chr9136062331 136062381 chr12 7994516 7994566 chr12 8857636 8857686 chr1211757176 11757226 chr12 32510748 32510798 chr12 54160277 54160327 chr1256776455 56776505 chr12 74195049 74195099 chr12 75400118 75400168 chr1297505100 97505150 chr10 31252721 31252771 chr13 54027032 54027082 chr1354033072 54033122 chr13 105292923 105292973 chr13 105292841 105292891chr13 112500214 112500264 chr14 28160143 28160193 chr10 4987523649875286 chr14 53935954 53936004 chr14 62168059 62168109 chr14 8812583688125886 chr14 88342508 88342558 chr14 102204340 102204390 chr14102391141 102391191 chr14 102750844 102750894 chr10 60029085 60029135chr15 43621850 43621900 chr15 53798580 53798630 chr15 94022203 94022253chr10 70147677 70147727 chr10 3024852 3024902 chr16 52094190 52094240chr16 56425008 56425058 chr16 84489047 84489097 chr17 2726633 2726683chr17 5940066 5940116 chr17 12501162 12501212 chr17 26929269 26929319Table 15DN. Repeat Category MSR1 chr19 7718302 7718352 chr19 77341937734243 chr19 40259425 40259475 chr19 41039038 41039088 chr19 4113698541137035 chr19 43926467 43926517 chr19 44379455 44379505 chr19 4437938544379435 chr19 44585311 44585361 chr19 44585656 44585706 chr19 4458591344585963 chr19 46009354 46009404 chr19 46009572 46009622 chr19 4633268646332736 chr19 46332881 46332931 chr19 47090604 47090654 chr19 4708998047090030 chr19 47098641 47098691 chr19 47180762 47180812 chr19 4726117347261223 chr19 47261422 47261472 chr19 47261098 47261148 chr19 4756610147566151 chr19 48610867 48610917 chr19 48611065 48611115 chr19 4861130148611351 chr19 48675115 48675165 chr19 48693386 48693436 chr19 4870273348702783 chr19 48821598 48821648 chr19 48823304 48823354 chr19 4997322349973273 chr19 50004302 50004352 chr19 50007509 50007559 chr19 5000846450008514 chr19 50069337 50069387 chr19 50068960 50069010 chr19 5358667753586727 chr19 53641833 53641883 chr19 53645623 53645673 chr19 5366490653664956 chr19 53794639 53794689 chr19 53909623 53909673 chr19 5395454353954593 chr19 54031956 54032006 chr19 54032859 54032909 chr19 5406777754067827 chr19 54091621 54091671 chr19 54095191 54095241 chr19 5409532654095376 chr19 54128856 54128906 chr19 54128659 54128709 chr19 5412871654128766 chr19 54180973 54181023 chr19 54180791 54180841 chr19 5418915754189207 chr19 54253689 54253739 chr19 54259965 54260015 chr19 5426007154260121 chr19 54320824 54320874 chr19 54353062 54353112 chr19 5436370654363756 chr19 54555046 54555096 chr19 54557467 54557517 chr19 5462115454621204 chr19 54631785 54631835 chr19 54707872 54707922 chr19 5481565854815708 chr19 54835803 54835853 chr19 54836265 54836315 chr19 5484128354841333 chr19 54861140 54861190 chr19 54887260 54887310 chr19 5497778354977833 chr19 54977525 54977575 chr19 54994844 54994894 chr19 5501385355013903 chr19 55646529 55646579 chr19 55662622 55662672 chr19 5582036155820411 chr19 55824307 55824357 chr19 56022427 56022477 chr19 5616374056163790 chr19 56194330 56194380 chr19 56196216 56196266 chr19 5619612956196179 chr19 56272488 56272538 chr19 56274637 56274687 chr19 5627454056274590 chr19 56532902 56532952 chr19 56583200 56583250 chr19 5658564456585694 chr19 56797010 56797060 chr19 56884480 56884530 chr19 5688753256887582 chr19 56887722 56887772 chr19 56887796 56887846 chr19 5906337059063420 chr19 59064702 59064752 chr19 59137020 59137070 chr19 5929087459290924 chr19 59310010 59310060 chr19 59365023 59365073 chr19 5961857959618629 chr19 60316982 60317032 chr19 60340229 60340279 chr19 6036500760365057 chr19 60427830 60427880 chr19 60427702 60427752 chr19 6050569660505746 chr19 60523332 60523382 chr19 60565462 60565512 chr19 6057260760572657 chr19 60577642 60577692 chr19 60640878 60640928 chr19 6064070260640752 chr19 60739403 60739453 chr19 60851697 60851747 Table 15DO.Repeat Category MSTA chr17 45888066 45888116 chr17 55581142 55581192chr17 57371424 57371474 chr10 86045933 86045983 chr17 62577665 62577715chr17 64354869 64354919 chr17 65298382 65298432 chr17 67042860 67042910chr17 71324294 71324344 chr17 73478286 73478336 chr17 75584998 75585048chr10 92395332 92395382 chr17 80912139 80912189 chr17 80913287 80913337chr17 81101333 81101383 chr17 81697356 81697406 chr18 516583 516633chr18 4418917 4418967 chr18 5631183 5631233 chr18 8411910 8411960 chr1819097151 19097201 chr18 27532763 27532813 chr18 28036231 28036281 chr1828036017 28036067 chr18 28388101 28388151 chr10 5014356 5014406 chr105013846 5013896 chr18 35450240 35450290 chr18 35498079 35498129 chr1843746242 43746292 chr18 50113828 50113878 chr18 53882989 53883039 chr1854596391 54596441 chr18 55399822 55399872 chr18 62284049 62284099 chr1867368054 67368104 chr18 67466511 67466561 chr18 68222456 68222506 chr1868935572 68935622 chr18 70615032 70615082 chr18 75838445 75838495 chr194993783 4993833 chr19 8998136 8998186 chr19 9119370 9119420 chr1912608461 12608511 chr19 14142639 14142689 chr19 14774019 14774069 chr1914773946 14773996 chr19 15033996 15034046 chr19 19728690 19728740 chr1934438741 34438791 chr10 5720358 5720408 chr19 37514377 37514427 chr1939261074 39261124 chr19 39462351 39462401 chr19 40201046 40201096 chr10104650009 104650059 chr19 44246012 44246062 chr19 45303470 45303520chr19 45348294 45348344 chr19 46902543 46902593 chr10 105726634105726684 chr10 5888108 5888158 chr19 47876848 47876898 chr10 107234376107234426 chr10 111510822 111510872 chr19 54661536 54661586 chr1957259576 57259626 chr19 57259638 57259688 chr19 57368812 57368862 chr10113412970 113413020 chr19 60418163 60418213 chr19 60977531 60977581chr19 61673912 61673962 chr19 62853071 62853121 chr19 63326067 63326117chr19 63325829 63325879 chr10 115206836 115206886 chr1 2524079 2524129chr1 3571643 3571693 chr1 4827952 4828002 chr1 5200128 5200178 chr15529622 5529672 chr1 7898773 7898823 chr1 7961784 7961834 chr1 1243524812435298 chr1 14345870 14345920 chr10 118575158 118575208 chr1 1685856416858614 chr1 17009439 17009489 chr1 17153095 17153145 chr1 1851624218516292 chr1 18539263 18539313 chr10 118822737 118822787 chr1 2023008020230130 chr10 119183648 119183698 chr1 21616192 21616242 chr1 2447876724478817 chr10 121467587 121467637 chr1 40985577 40985627 chr1 4298507842985128 chr1 62190833 62190883 chr1 67103364 67103414 chr1 6849727968497329 chr1 70297151 70297201 chr1 72083574 72083624 chr1 7213827472138324 chr1 79285858 79285908 chr1 81017631 81017681 chr1 8238640382386453 chr1 83622755 83622805 chr1 85130152 85130202 chr1 8623358986233639 chr1 92028569 92028619 chr1 110884704 110884754 chr10 126185829126185879 chr1 112628853 112628903 chr1 152614436 152614486 chr1153203479 153203529 chr1 153203869 153203919 chr1 175867474 175867524chr1 193173421 193173471 chr1 200359027 200359077 chr1 201186284201186334 chr1 201186822 201186872 chr1 204138933 204138983 chr1204489468 204489518 chr1 206286596 206286646 chr1 210173229 210173279chr1 212443612 212443662 chr1 215706938 215706988 chr1 216210168216210218 chr1 217975141 217975191 chr1 219405209 219405259 chr1221776796 221776846 chr1 227660466 227660516 chr1 228014767 228014817chr1 230969101 230969151 chr1 232786093 232786143 chr10 131804646131804696 chr1 236724634 236724684 chr1 238449796 238449846 chr1239153469 239153519 chr1 239161866 239161916 chr1 242455444 242455494chr1 243569426 243569476 chr20 1599328 1599378 chr20 9587813 9587863chr20 10419827 10419877 chr20 11741957 11742007 chr20 12564601 12564651chr20 25214568 25214618 chr20 25214677 25214727 chr10 133507886133507936 chr20 33443400 33443450 chr20 39407139 39407189 chr20 3941306539413115 chr20 43062274 43062324 chr20 46064724 46064774 chr20 4606483746064887 chr20 46065723 46065773 chr20 46159502 46159552 chr20 4784272147842771 chr20 51560862 51560912 chr20 52851641 52851691 chr20 5596295455963004 chr20 56756651 56756701 chr20 61370607 61370657 chr20 6312119863121248 chr21 14152879 14152929 chr21 17719211 17719261 chr21 1799745517997505 chr21 20185894 20185944 chr21 23113678 23113728 chr21 2378508723785137 chr21 27012980 27013030 chr21 27118714 27118764 chr21 2929276929292819 chr21 30780124 30780174 chr21 30779987 30780037 chr21 3346951233469562 chr21 34986548 34986598 chr21 36372195 36372245 chr21 3904346939043519 chr21 39043790 39043840 chr21 39410826 39410876 chr21 3961646739616517 chr21 39872516 39872566 chr21 41049265 41049315 chr21 4191399741914047 chr21 42989815 42989865 chr21 44937529 44937579 chr21 4494884144948891 chr21 44954095 44954145 chr21 45573639 45573689 chr21 4557378545573835 chr21 45873464 45873514 chr21 46239884 46239934 chr22 1617229316172343 chr22 16370831 16370881 chr22 18030983 18031033 chr11 13631131363163 chr22 24135046 24135096 chr22 26348850 26348900 chr22 2726084927260899 chr22 32080385 32080435 chr22 32081435 32081485 chr22 4018629240186342 chr22 41150166 41150216 chr22 41408584 41408634 chr22 4323165543231705 chr10 10128867 10128917 chr22 43790731 43790781 chr22 4558587445585924 chr22 45648763 45648813 chr11 3177908 3177958 chr22 4770173747701787 chr22 48270471 48270521 chr22 48519005 48519055 chrX 26846222684672 chrX 3987288 3987338 chrX 11654542 11654592 chrX 1587307515873125 chrX 17839781 17839831 chrX 23808855 23808905 chrX 2386085923860909 chrX 26252159 26252209 chrX 34622260 34622310 chrX 3858952738589577 chrX 45118395 45118445 chrX 46155942 46155992 chrX 4626395346264003 chrX 52586295 52586345 chrX 55875396 55875446 chrX 7492752274927572 chrX 76534776 76534826 chrX 87673683 87673733 chrX 8897549488975544 chrX 88978739 88978789 chrX 90283563 90283613 chrX 9148921191489261 chrX 92067282 92067332 chrX 98270218 98270268 chrX 101446981101447031 chrX 104114023 104114073 chr11 9758708 9758758 chrX 109423715109423765 chrX 109644277 109644327 chrX 115282502 115282552 chrX115284223 115284273 chrX 118930248 118930298 chrX 119261973 119262023chrX 125201551 125201601 chrX 128413316 128413366 chrX 129714867129714917 chrX 138959582 138959632 chrX 139810344 139810394 chrX143283619 143283669 chrX 147627879 147627929 chrX 147630067 147630117chrX 148332296 148332346 chrX 150986787 150986837 chr11 1345128013451330 chrX 151740030 151740080 chrX 153124337 153124387 chrY 52752295275279 chrY 22280806 22280856 chr2 855052 855102 chr2 1327377 1327427chr2 2051572 2051622 chr11 16062323 16062373 chr11 16062979 16063029chr2 4953172 4953222 chr2 5543347 5543397 chr2 6656045 6656095 chr211561259 11561309 chr2 11843539 11843589 chr2 21384804 21384854 chr227228368 27228418 chr2 37943678 37943728 chr2 38513946 38513996 chr242302034 42302084 chr2 46408570 46408620 chr2 53909678 53909728 chr261853286 61853336 chr2 61975369 61975419 chr11 23624442 23624492 chr263955323 63955373 chr2 65214840 65214890 chr2 68695855 68695905 chr1125286792 25286842 chr2 70620206 70620256 chr2 73940191 73940241 chr275927671 75927721 chr2 79204062 79204112 chr2 81768009 81768059 chr286761525 86761575 chr2 86845934 86845984 chr2 97142279 97142329 chr2101375431 101375481 chr2 104537746 104537796 chr2 106535639 106535689chr2 107255191 107255241 chr2 115423706 115423756 chr2 117881546117881596 chr2 120543299 120543349 chr2 129467410 129467460 chr2132247539 132247589 chr2 132435344 132435394 chr2 132781839 132781889chr2 134059821 134059871 chr2 135045643 135045693 chr2 143654440143654490 chr2 158435665 158435715 chr2 158561622 158561672 chr1135539748 35539798 chr2 173750757 173750807 chr2 176107921 176107971 chr2180134858 180134908 chr2 180187590 180187640 chr2 180376220 180376270chr2 183445032 183445082 chr11 38518519 38518569 chr2 189623995189624045 chr2 190825264 190825314 chr2 191468339 191468389 chr2194041993 194042043 chr2 201241943 201241993 chr2 203411046 203411096chr2 204326801 204326851 chr11 40716816 40716866 chr2 205710604205710654 chr2 205897391 205897441 chr2 209127422 209127472 chr2212783315 212783365 chr2 216245556 216245606 chr2 221868986 221869036chr2 225788560 225788610 chr2 228752354 228752404 chr2 229665053229665103 chr2 231495633 231495683 chr2 232039565 232039615 chr2237140789 237140839 chr2 237450368 237450418 chr11 45826640 45826690chr2 240177162 240177212 chr2 240258521 240258571 chr2 240687231240687281 chr2 240955994 240956044 chr2 241452682 241452732 chr2241790134 241790184 chr2 242990764 242990814 chr2 243250171 243250221chr3 3138199 3138249 chr3 8761838 8761888 chr3 8761533 8761583 chr314988961 14989011 chr3 23116559 23116609 chr3 24005272 24005322 chr332714680 32714730 chr10 12458739 12458789 chr3 45240122 45240172 chr347815106 47815156 chr3 50734107 50734157 chr3 54093250 54093300 chr1156991717 56991767 chr3 75381757 75381807 chr3 77709533 77709583 chr380629199 80629249 chr3 86019685 86019735 chr3 88990148 88990198 chr396783608 96783658 chr3 100845901 100845951 chr3 101219199 101219249chr11 59243434 59243484 chr3 103318236 103318286 chr3 106096590106096640 chr3 116223969 116224019 chr3 118991853 118991903 chr3120152768 120152818 chr3 123478029 123478079 chr3 138605672 138605722chr3 142022022 142022072 chr3 147084997 147085047 chr3 154870852154870902 chr3 159181223 159181273 chr3 164527020 164527070 chr3173574851 173574901 chr3 176977474 176977524 chr3 179039437 179039487chr3 184510826 184510876 chr10 13003536 13003586 chr3 192143533192143583 chr3 193256818 193256868 chr3 193669201 193669251 chr3194807740 194807790 chr3 195950575 195950625 chr3 199104385 199104435chr4 450692 450742 chr4 2000184 2000234 chr4 3727039 3727089 chr45158919 5158969 chr4 5471508 5471558 chr4 10596341 10596391 chr413826446 13826496 chr4 15486246 15486296 chr4 15640723 15640773 chr419911333 19911383 chr4 22618991 22619041 chr4 24422495 24422545 chr428670052 28670102 chr4 36572828 36572878 chr4 38169964 38170014 chr443313853 43313903 chr4 44160312 44160362 chr4 53374935 53374985 chr453374657 53374707 chr4 54038863 54038913 chr4 62007396 62007446 chr477469265 77469315 chr4 77616808 77616858 chr4 77836731 77836781 chr478234526 78234576 chr10 13437896 13437946 chr4 84411789 84411839 chr484479609 84479659 chr4 84867263 84867313 chr4 87928272 87928322 chr490660950 90661000 chr4 95513132 95513182 chr4 95776780 95776830 chr4108017000 108017050 chr4 109868345 109868395 chr4 120062619 120062669chr4 128246962 128247012 chr11 66515968 66516018 chr4 132448019132448069 chr4 134330513 134330563 chr4 137075973 137076023 chr4137321225 137321275 chr4 138218022 138218072 chr4 144489594 144489644chr4 149641092 149641142 chr4 154214420 154214470 chr4 157952073157952123 chr4 158549665 158549715 chr4 159769355 159769405 chr4164038975 164039025 chr4 164727053 164727103 chr4 166271186 166271236chr4 166297456 166297506 chr4 173240078 173240128 chr4 182150208182150258 chr4 183681750 183681800 chr4 183682808 183682858 chr4185950684 185950734 chr4 186738753 186738803 chr4 186739076 186739126chr11 68505537 68505587 chr5 2320972 2321022 chr5 2575289 2575339 chr54331870 4331920 chr5 4745567 4745617 chr11 69110189 69110239 chr57990087 7990137 chr5 12819201 12819251 chr5 12919543 12919593 chr517215200 17215250 chr5 20064688 20064738 chr5 20954939 20954989 chr1169570417 69570467 chr5 23290344 23290394 chr5 24214950 24215000 chr524215873 24215923 chr5 24215682 24215732 chr5 25767537 25767587 chr525932853 25932903 chr5 26081418 26081468 chr5 26322417 26322467 chr534340955 34341005 chr5 35994756 35994806 chr5 52917983 52918033 chr555985412 55985462 chr5 56594539 56594589 chr5 56887679 56887729 chr1170531815 70531865 chr5 77202934 77202984 chr5 78547584 78547634 chr1170854433 70854483 chr11 70898692 70898742 chr5 81327129 81327179 chr586700779 86700829 chr5 86700589 86700639 chr5 88708465 88708515 chr594908683 94908733 chr5 101902448 101902498 chr5 101903695 101903745 chr5103022756 103022806 chr5 104511195 104511245 chr5 108647406 108647456chr5 109396103 109396153 chr5 110563659 110563709 chr5 110998474110998524 chr5 114157001 114157051 chr5 114212915 114212965 chr5116234548 116234598 chr11 71946042 71946092 chr5 119558610 119558660chr5 125568950 125569000 chr5 125950085 125950135 chr5 127591699127591749 chr5 131595596 131595646 chr5 139028053 139028103 chr5152241936 152241986 chr5 162752278 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8483059084830640 chr13 88613062 88613112 chr13 90772051 90772101 chr13 9138186091381910 chr13 93754404 93754454 chr13 99776196 99776246 chr13 101063117101063167 chr13 102073633 102073683 chr13 104143792 104143842 chr13107979735 107979785 chr13 109723080 109723130 chr13 111854214 111854264chr13 112673322 112673372 chr13 112808979 112809029 chr14 2471969924719749 chr14 29317806 29317856 chr14 29860446 29860496 chr14 3276459532764645 chr14 35515904 35515954 chr14 36469551 36469601 chr10 4989259249892642 chr14 52293911 52293961 chr14 61795563 61795613 chr14 6213651862136568 chr14 62260629 62260679 chr14 63572535 63572585 chr14 6500802865008078 chr14 70535491 70535541 chr14 70534968 70535018 chr14 7075172470751774 chr14 70783276 70783326 chr14 73208700 73208750 chr14 8380458883804638 chr10 54112943 54112993 chr14 85934537 85934587 chr14 9345676293456812 chr14 93700748 93700798 chr10 56302678 56302728 chr14 9742984997429899 chr14 99628899 99628949 chr14 100610040 100610090 chr1060096274 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Repeat Category MSTB chr10 82267400 82267450 chr17 4856755748567607 chr17 54421646 54421696 chr17 55351216 55351266 chr17 5615982656159876 chr17 57505478 57505528 chr10 86464464 86464514 chr17 6657570366575753 chr17 67741387 67741437 chr17 70585186 70585236 chr17 7572993875729988 chr17 76052877 76052927 chr17 78945383 78945433 chr17 8091213980912189 chr17 80913287 80913337 chr17 81608104 81608154 chr18 993795993845 chr18 2701766 2701816 chr10 95386206 95386256 chr18 2738952027389570 chr18 29626733 29626783 chr18 46096167 46096217 chr18 4931450449314554 chr10 5241164 5241214 chr18 58320407 58320457 chr10 52911005291150 chr18 61887606 61887656 chr18 64211715 64211765 chr18 6737092267370972 chr18 69950420 69950470 chr18 72270481 72270531 chr18 7249263272492682 chr18 74944223 74944273 chr18 74944003 74944053 chr19 339779339829 chr19 605054 605104 chr19 1656176 1656226 chr19 5719746 5719796chr19 6087882 6087932 chr19 10987160 10987210 chr19 11090057 11090107chr19 11607484 11607534 chr19 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180813005 chr3 182983482 182983532chr3 186256268 186256318 chr3 186287720 186287770 chr3 186422313186422363 chr3 187851359 187851409 chr3 189553527 189553577 chr3192445644 192445694 chr3 196286041 196286091 chr4 508270 508320 chr45026171 5026221 chr4 11753452 11753502 chr4 14996354 14996404 chr415867733 15867783 chr4 17136944 17136994 chr4 18575341 18575391 chr424540849 24540899 chr4 31192895 31192945 chr4 46750403 46750453 chr447575168 47575218 chr4 54937449 54937499 chr4 67868869 67868919 chr470977706 70977756 chr4 72208133 72208183 chr4 90725576 90725626 chr4104009332 104009382 chr4 106744571 106744621 chr4 117383824 117383874chr4 119965655 119965705 chr4 124762191 124762241 chr4 125671442125671492 chr4 126541857 126541907 chr4 132366697 132366747 chr4134017331 134017381 chr4 135054156 135054206 chr4 139626989 139627039chr4 140166425 140166475 chr4 163640181 163640231 chr4 165130903165130953 chr4 168343862 168343912 chr4 169337258 169337308 chr4169337659 169337709 chr4 177354751 177354801 chr4 179018082 179018132chr4 179237751 179237801 chr4 180437491 180437541 chr4 181203613181203663 chr4 185075468 185075518 chr4 185935433 185935483 chr4190931367 190931417 chr5 767762 767812 chr5 852060 852110 chr5 23419772342027 chr5 3297205 3297255 chr5 9184142 9184192 chr5 15010471 15010521chr5 16962395 16962445 chr5 20852747 20852797 chr5 26979439 26979489chr5 31975672 31975722 chr5 32230998 32231048 chr5 34442340 34442390chr5 37286089 37286139 chr11 70015849 70015899 chr5 43321614 43321664chr5 43620931 43620981 chr5 43620708 43620758 chr5 55084043 55084093chr5 55144305 55144355 chr5 62116687 62116737 chr5 62116753 62116803chr5 67129551 67129601 chr11 70553759 70553809 chr11 70553692 70553742chr5 74305828 74305878 chr5 76127961 76128011 chr11 70775900 70775950chr5 92010868 92010918 chr5 92195265 92195315 chr5 93644209 93644259chr5 98686461 98686511 chr11 71946042 71946092 chr5 118876968 118877018chr5 124274859 124274909 chr5 124276306 124276356 chr5 133429849133429899 chr11 73111150 73111200 chr5 139672162 139672212 chr5154069475 154069525 chr5 171284437 171284487 chr5 171284271 171284321chr5 172429660 172429710 chr5 175848410 175848460 chr11 7589836175898411 chr5 177509254 177509304 chr5 177734065 177734115 chr5178484311 178484361 chr6 3511935 3511985 chr6 6742591 6742641 chr611484584 11484634 chr6 14695949 14695999 chr6 16049543 16049593 chr617279170 17279220 chr6 17408463 17408513 chr6 17466319 17466369 chr618134481 18134531 chr6 22642952 22643002 chr6 23679967 23680017 chr627446473 27446523 chr6 32796124 32796174 chr10 15241373 15241423 chr645408463 45408513 chr6 47630144 47630194 chr6 49510392 49510442 chr1188237218 88237268 chr6 63965557 63965607 chr11 89684981 89685031 chr674398785 74398835 chr6 76474844 76474894 chr6 85758144 85758194 chr686022358 86022408 chr11 92325486 92325536 chr6 90333708 90333758 chr6103686484 103686534 chr6 107629014 107629064 chr6 109186186 109186236chr6 115624784 115624834 chr6 116960864 116960914 chr6 120361677120361727 chr6 124817572 124817622 chr6 124817407 124817457 chr6126457377 126457427 chr6 129824969 129825019 chr6 131445396 131445446chr6 134431790 134431840 chr6 135074792 135074842 chr6 135114416135114466 chr6 138301200 138301250 chr6 140255093 140255143 chr6143743612 143743662 chr6 144578458 144578508 chr6 146916571 146916621chr11 100825792 100825842 chr6 158640582 158640632 chr6 160156726160156776 chr11 101798229 101798279 chr11 101812586 101812636 chr6161345981 161346031 chr6 166012383 166012433 chr7 1648753 1648803 chr71916827 1916877 chr7 3687404 3687454 chr11 109777172 109777222 chr710859779 10859829 chr7 15545104 15545154 chr7 21742240 21742290 chr724507279 24507329 chr7 26203804 26203854 chr11 111438717 111438767 chr730166593 30166643 chr7 30166673 30166723 chr11 111635965 111636015 chr737470800 37470850 chr7 44451749 44451799 chr7 45193199 45193249 chr747457236 47457286 chr7 63572288 63572338 chr7 65275522 65275572 chr768411773 68411823 chr7 70119658 70119708 chr7 70432871 70432921 chr770659204 70659254 chr7 70658923 70658973 chr7 71026673 71026723 chr771276649 71276699 chr7 72608830 72608880 chr7 74957472 74957522 chr778741810 78741860 chr7 89633972 89634022 chr7 97475261 97475311 chr797570944 97570994 chr7 98034044 98034094 chr7 98576035 98576085 chr7100267427 100267477 chr7 100648877 100648927 chr7 101473407 101473457chr7 104234760 104234810 chr7 113328809 113328859 chr7 123204395123204445 chr7 123930634 123930684 chr11 118116141 118116191 chr7130222718 130222768 chr7 135138367 135138417 chr7 143039189 143039239chr11 118849783 118849833 chr7 148058302 148058352 chr7 150787128150787178 chr7 150986282 150986332 chr7 151059258 151059308 chr7151714738 151714788 chr7 152190369 152190419 chr7 152238506 152238556chr7 154390167 154390217 chr7 154967890 154967940 chr7 155463705155463755 chr7 156038532 156038582 chr7 157800037 157800087 chr7157799859 157799909 chr8 1672947 1672997 chr8 2039844 2039894 chr11121402439 121402489 chr8 4699197 4699247 chr8 6147929 6147979 chr11121705789 121705839 chr10 18281274 18281324 chr8 9984662 9984712 chr813686403 13686453 chr8 16570215 16570265 chr11 122549858 122549908 chr821283134 21283184 chr11 122849124 122849174 chr11 123170295 123170345chr10 18536301 18536351 chr8 32734976 32735026 chr8 33933912 33933962chr8 36267203 36267253 chr8 37825367 37825417 chr8 39346162 39346212chr8 39617457 39617507 chr8 40224296 40224346 chr8 49718688 49718738chr8 50121037 50121087 chr8 55790827 55790877 chr8 57023351 57023401chr8 64126579 64126629 chr8 72728256 72728306 chr8 76541573 76541623chr8 77022855 77022905 chr8 81063922 81063972 chr8 81607390 81607440chr8 83576394 83576444 chr8 94528535 94528585 chr8 96416556 96416606chr8 98401755 98401805 chr8 98717863 98717913 chr8 101044009 101044059chr8 103428828 103428878 chr8 112772098 112772148 chr8 118020662118020712 chr8 123648457 123648507 chr8 126970044 126970094 chr8130318850 130318900 chr8 131500714 131500764 chr8 134859343 134859393chr8 137294881 137294931 chr8 141924114 141924164 chr8 144252762144252812 chr8 144252687 144252737 chr8 144441241 144441291 chr8144441942 144441992 chr8 144951500 144951550 chr11 130929079 130929129chr11 131062555 131062605 chr8 145861459 145861509 chr10 1980620419806254 chr9 6580065 6580115 chr11 132408352 132408402 chr9 2071347420713524 chr9 36402501 36402551 chr9 38085827 38085877 chr9 6734134167341391 chr9 81492799 81492849 chr9 82987343 82987393 chr9 8362281783622867 chr9 83622669 83622719 chr9 83945559 83945609 chr9 8394616383946213 chr9 83946297 83946347 chr9 86094921 86094971 chr9 8609517486095224 chr9 86220786 86220836 chr9 87287030 87287080 chr11 134025879134025929 chr9 103627572 103627622 chr9 110486938 110486988 chr9110881909 110881959 chr9 116834074 116834124 chr9 120975059 120975109chr9 122052502 122052552 chr9 128220736 128220786 chr9 128660480128660530 chr9 130046797 130046847 chr9 130046656 130046706 chr1021641642 21641692 chr9 133167436 133167486 chr12 4154188 4154238 chr124207661 4207711 chr12 5690728 5690778 chr12 7787855 7787905 chr1210883590 10883640 chr10 22870670 22870720 chr12 21238279 21238329 chr1024039681 24039731 chr10 24057720 24057770 chr12 26387101 26387151 chr1226618966 26619016 chr12 27357528 27357578 chr12 33236546 33236596 chr1234254285 34254335 chr12 54563810 54563860 chr12 61303385 61303435 chr1267979557 67979607 chr10 28926586 28926636 chr12 76921358 76921408 chr1278325177 78325227 chr12 83876692 83876742 chr12 84127839 84127889 chr1298359524 98359574 chr12 102853073 102853123 chr12 112386976 112387026chr12 115191144 115191194 chr10 31447112 31447162 chr12 116927846116927896 chr12 124427256 124427306 chr12 124640271 124640321 chr12126755663 126755713 chr12 128351001 128351051 chr12 129609979 129610029chr13 18249389 18249439 chr13 27048486 27048536 chr13 28646991 28647041chr13 29447391 29447441 chr13 31917515 31917565 chr13 35106082 35106132chr13 39076798 39076848 chr13 44604251 44604301 chr13 46799072 46799122chr13 46798806 46798856 chr13 50262066 50262116 chr13 53462193 53462243chr13 53840773 53840823 chr13 55501386 55501436 chr13 59800054 59800104chr13 65370217 65370267 chr13 72012773 72012823 chr13 74499453 74499503chr13 76022076 76022126 chr13 77739914 77739964 chr13 83837723 83837773chr13 84150559 84150609 chr13 87785426 87785476 chr13 96701986 96702036chr13 97027878 97027928 chr13 97754562 97754612 chr10 43522029 43522079chr13 106257692 106257742 chr13 106257604 106257654 chr13 111649032111649082 chr14 22393930 22393980 chr14 22393844 22393894 chr14 2265823122658281 chr14 32552191 32552241 chr14 39184578 39184628 chr14 4651048646510536 chr14 49632226 49632276 chr14 51652487 51652537 chr10 5086178450861834 chr14 66800897 66800947 chr14 71878938 71878988 chr14 7351436573514415 chr14 73515627 73515677 chr10 52923500 52923550 chr14 7552775775527807 chr14 79773603 79773653 chr14 79785522 79785572 chr14 8026463980264689 chr14 83809998 83810048 chr14 84851761 84851811 chr14 9021823990218289 chr14 93860396 93860446 chr14 94249122 94249172 chr14 9841853398418583 chr14 100842001 100842051 chr14 104880917 104880967 chr1521727893 21727943 chr15 27487486 27487536 chr15 38538232 38538282 chr1553356617 53356667 chr10 65518292 65518342 chr15 57763922 57763972 chr1565933522 65933572 chr15 72919310 72919360 chr15 72921328 72921378 chr1574756056 74756106 chr15 84997327 84997377 chr15 90837864 90837914 chr1591869794 91869844 chr15 96698975 96699025 chr16 38494 38544 chr161281875 1281925 chr16 1803005 1803055 chr16 11443726 11443776 chr1612221655 12221705 chr16 12222473 12222523 chr16 12476621 12476671 chr1615263834 15263884 chr16 15623946 15623996 chr16 16553085 16553135 chr1618118433 18118483 chr16 22644299 22644349 chr16 22714231 22714281 chr1622942215 22942265 chr16 26559308 26559358 chr16 30203275 30203325 chr1646677611 46677661 chr16 50308674 50308724 chr16 53156359 53156409 chr1654108194 54108244 chr16 54427736 54427786 chr10 73260659 73260709 chr1073315096 73315146 chr16 59018412 59018462 chr16 59056896 59056946 chr1681209664 81209714 chr16 85443893 85443943 chr16 86967473 86967523 chr1687615363 87615413 chr16 87994456 87994506 chr16 89434528 89434578 chr173810475 3810525 chr17 6145797 6145847 chr17 6956749 6956799 chr176957302 6957352 chr17 8879079 8879129 chr17 12646700 12646750 chr1714566587 14566637 chr17 15229635 15229685 chr17 16684482 16684532 chr1717760955 17761005 chr17 35714619 35714669 Table 15DQ. Repeat CategoryMSTB-int chr17 48567557 48567607 chr17 54421646 54421696 chr18 6188760661887656 chr1 46839776 46839826 chr11 4786972 4787022 chrX 7161268371612733 chrX 86766044 86766094 chrX 93600896 93600946 chr2 113642954113643004 chr3 147400213 147400263 chr4 18575341 18575391 chr4 4757516847575218 chr4 124762191 124762241 chr4 126541857 126541907 chr4190931367 190931417 chr5 98686461 98686511 chr11 71946042 71946092 chr614695949 14695999 chr6 76474844 76474894 chr6 86022358 86022408 chr6126457377 126457427 chr7 101473407 101473457 chr11 123170295 123170345chr8 77022855 77022905 chr8 144252762 144252812 chr8 144252687 144252737chr11 134025879 134025929 chr9 120975059 120975109 chr12 2123827921238329 chr13 39076798 39076848 chr13 74499453 74499503 chr14 6680089766800947 chr14 104880917 104880967 chr15 90837864 90837914 Table 15DR.Repeat Category MSTB1 chr10 82267400 82267450 chr17 55351216 55351266chr17 57505478 57505528 chr17 67741387 67741437 chr17 70585186 70585236chr17 80912139 80912189 chr17 80913287 80913337 chr17 81608104 81608154chr18 2701766 2701816 chr18 29626733 29626783 chr18 46096167 46096217chr18 49314504 49314554 chr18 58320407 58320457 chr18 69950420 69950470chr19 1656176 1656226 chr19 6087882 6087932 chr19 10987160 10987210chr19 17473222 17473272 chr19 33636370 33636420 chr10 105192813105192863 chr10 105193243 105193293 chr10 105193529 105193579 chr1953296313 53296363 chr19 56327657 56327707 chr1 5268962 5269012 chr113647332 13647382 chr1 14216346 14216396 chr1 26126487 26126537 chr157886437 57886487 chr1 58028929 58028979 chr1 58989326 58989376 chr190255661 90255711 chr10 125379054 125379104 chr10 125378842 125378892chr1 108556221 108556271 chr1 164029617 164029667 chr1 173130455173130505 chr1 191578364 191578414 chr1 225213113 225213163 chr1225589050 225589100 chr1 227455774 227455824 chr1 231470261 231470311chr1 240132156 240132206 chr20 31502272 31502322 chr10 134609524134609574 chr20 63479487 63479537 chr21 16014761 16014811 chr21 3260148932601539 chr21 33956644 33956694 chr21 40849941 40849991 chr21 4282224742822297 chr22 16104214 16104264 chr22 16526760 16526810 chr22 1840804718408097 chr22 41846210 41846260 chrX 15071533 15071583 chrX 2383298723833037 chrX 34433193 34433243 chrX 48016926 48016976 chrX 5060831450608364 chrX 53083196 53083246 chrX 81863466 81863516 chrX 117231013117231063 chrX 117654850 117654900 chrX 131646562 131646612 chrX140212967 140213017 chrY 6122806 6122856 chr2 3178777 3178827 chr230408202 30408252 chr2 61969776 61969826 chr11 25574739 25574789 chr1125574558 25574608 chr2 85903251 85903301 chr2 98044846 98044896 chr2115439544 115439594 chr2 121437900 121437950 chr2 129438915 129438965chr2 138594488 138594538 chr2 143495291 143495341 chr2 151718328151718378 chr2 202178389 202178439 chr2 202178325 202178375 chr2203129931 203129981 chr2 216982642 216982692 chr2 231957341 231957391chr11 45801643 45801693 chr2 241454760 241454810 chr2 241844409241844459 chr3 16491880 16491930 chr3 16491653 16491703 chr3 1792392117923971 chr3 41847584 41847634 chr3 45140512 45140562 chr3 4981442649814476 chr3 80430511 80430561 chr3 88176564 88176614 chr3 158176367158176417 chr3 176081746 176081796 chr3 186422313 186422363 chr411753452 11753502 chr4 17136944 17136994 chr4 67868869 67868919 chr472208133 72208183 chr4 119965655 119965705 chr4 179237751 179237801 chr4181203613 181203663 chr4 185935433 185935483 chr5 767762 767812 chr5852060 852110 chr5 3297205 3297255 chr5 16962395 16962445 chr5 2085274720852797 chr5 26979439 26979489 chr5 34442340 34442390 chr11 7001584970015899 chr5 55084043 55084093 chr5 62116687 62116737 chr5 6211675362116803 chr5 67129551 67129601 chr5 171284437 171284487 chr5 171284271171284321 chr5 175848410 175848460 chr11 75898361 75898411 chr5177509254 177509304 chr6 17466319 17466369 chr6 22642952 22643002 chr623679967 23680017 chr6 27446473 27446523 chr6 49510392 49510442 chr1188237218 88237268 chr11 89684981 89685031 chr6 74398785 74398835 chr1192325486 92325536 chr6 90333708 90333758 chr6 103686484 103686534 chr6116960864 116960914 chr6 124817572 124817622 chr6 124817407 124817457chr6 134431790 134431840 chr6 143743612 143743662 chr6 144578458144578508 chr11 100825792 100825842 chr6 161345981 161346031 chr6166012383 166012433 chr7 1648753 1648803 chr7 1916827 1916877 chr73687404 3687454 chr7 15545104 15545154 chr7 21742240 21742290 chr730166593 30166643 chr7 30166673 30166723 chr7 44451749 44451799 chr770119658 70119708 chr7 71026673 71026723 chr7 78741810 78741860 chr797475261 97475311 chr7 150986282 150986332 chr8 6147929 6147979 chr816570215 16570265 chr8 21283134 21283184 chr10 18536301 18536351 chr832734976 32735026 chr8 37825367 37825417 chr8 39346162 39346212 chr849718688 49718738 chr8 55790827 55790877 chr8 76541573 76541623 chr883576394 83576444 chr8 98717863 98717913 chr8 137294881 137294931 chr11130929079 130929129 chr9 6580065 6580115 chr9 81492799 81492849 chr982987343 82987393 chr9 133167436 133167486 chr12 4154188 4154238 chr124207661 4207711 chr10 22870670 22870720 chr10 24039681 24039731 chr1024057720 24057770 chr12 34254285 34254335 chr12 76921358 76921408 chr1278325177 78325227 chr12 102853073 102853123 chr12 115191144 115191194chr10 31447112 31447162 chr12 116927846 116927896 chr12 129609979129610029 chr13 18249389 18249439 chr13 29447391 29447441 chr13 3191751531917565 chr13 50262066 50262116 chr13 53462193 53462243 chr13 5384077353840823 chr13 59800054 59800104 chr13 72012773 72012823 chr13 7602207676022126 chr10 43522029 43522079 chr14 32552191 32552241 chr14 4963222649632276 chr10 50861784 50861834 chr14 73514365 73514415 chr14 7351562773515677 chr10 52923500 52923550 chr14 79785522 79785572 chr14 8485176184851811 chr14 98418533 98418583 chr15 21727893 21727943 chr15 5335661753356667 chr15 72919310 72919360 chr15 72921328 72921378 chr15 7475605674756106 chr16 1803005 1803055 chr16 15263834 15263884 chr16 1562394615623996 chr16 16553085 16553135 chr16 22714231 22714281 chr16 2294221522942265 chr16 46677611 46677661 chr16 53156359 53156409 chr16 8799445687994506 chr16 89434528 89434578 chr17 8879079 8879129 chr17 1668448216684532 Table 15DS. Repeat Category MSTC chr17 49223574 49223624 chr1758265918 58265968 chr17 75176876 75176926 chr17 77265523 77265573 chr186319433 6319483 chr18 7935504 7935554 chr18 7935063 7935113 chr1094645208 94645258 chr18 39054226 39054276 chr18 45254771 45254821 chr1847025108 47025158 chr19 2752743 2752793 chr19 7996493 7996543 chr1951224142 51224192 chr10 112101943 112101993 chr19 59229744 59229794chr19 62654555 62654605 chr1 20160557 20160607 chr1 23841184 23841234chr1 39857947 39857997 chr1 45267386 45267436 chr1 46209492 46209542chr1 87428705 87428755 chr1 109279029 109279079 chr1 112843013 112843063chr1 114419057 114419107 chr10 127358135 127358185 chr1 180554469180554519 chr1 184956525 184956575 chr1 198067310 198067360 chr1205954407 205954457 chr1 215685991 215686041 chr1 228043173 228043223chr10 131829430 131829480 chr1 244076008 244076058 chr1 244426531244426581 chr20 4027071 4027121 chr20 4306659 4306709 chr20 51978935197943 chr20 25353621 25353671 chr20 31707957 31708007 chr10 79301797930229 chr20 50683379 50683429 chr20 57196000 57196050 chr21 1510193115101981 chr21 22921165 22921215 chr11 869773 869823 chr22 1652676016526810 chr22 19048340 19048390 chr22 25002284 25002334 chr22 2974040029740450 chr22 37902423 37902473 chr22 40095366 40095416 chr22 4237920242379252 chr22 42875195 42875245 chr22 48955466 48955516 chrX 3975393739753987 chrX 46738835 46738885 chrX 53093966 53094016 chrX 5310307053103120 chrX 61386426 61386476 chrX 62045450 62045500 chrX 117223119117223169 chrX 138756298 138756348 chrX 153122807 153122857 chr2 35844743584524 chr2 9324308 9324358 chr2 10423470 10423520 chr2 2101222621012276 chr2 38035945 38035995 chr2 63841612 63841662 chr2 6584441165844461 chr2 66263669 66263719 chr2 83210236 83210286 chr2 101679313101679363 chr2 104127966 104128016 chr2 127723082 127723132 chr1133178388 33178438 chr2 179321318 179321368 chr2 218715874 218715924 chr2240591870 240591920 chr3 28804440 28804490 chr3 86523315 86523365 chr3107085198 107085248 chr3 121011643 121011693 chr3 127060492 127060542chr3 154271240 154271290 chr3 175465669 175465719 chr3 178139841178139891 chr3 188246468 188246518 chr3 188246264 188246314 chr1163115209 63115259 chr4 36418577 36418627 chr4 74383772 74383822 chr484413645 84413695 chr11 65992489 65992539 chr4 102355966 102356016 chr4134128027 134128077 chr4 139195747 139195797 chr4 149209592 149209642chr4 179545333 179545383 chr5 26997896 26997946 chr5 40506098 40506148chr5 42221006 42221056 chr5 42220756 42220806 chr5 53381788 53381838chr5 55363659 55363709 chr11 70600025 70600075 chr5 74443459 74443509chr5 118871576 118871626 chr5 129990024 129990074 chr5 165683010165683060 chr5 168745591 168745641 chr5 180025883 180025933 chr6 393123393173 chr6 6744907 6744957 chr11 78349472 78349522 chr6 3056737930567429 chr6 32400938 32400988 chr6 42725398 42725448 chr6 146448076146448126 chr6 155240929 155240979 chr6 158725212 158725262 chr6161760821 161760871 chr11 107236880 107236930 chr7 4317485 4317535 chr75510871 5510921 chr7 7011368 7011418 chr7 19142316 19142366 chr769816616 69816666 chr7 69916233 69916283 chr7 86231719 86231769 chr790239855 90239905 chr7 96288395 96288445 chr11 117950493 117950543 chr7147377214 147377264 chr7 152250288 152250338 chr7 156441007 156441057chr7 156440791 156440841 chr8 23068626 23068676 chr8 81352205 81352255chr8 131891567 131891617 chr8 144846403 144846453 chr9 8900388 8900438chr9 34663243 34663293 chr9 37744942 37744992 chr9 67112392 67112442chr9 71076714 71076764 chr9 85796398 85796448 chr9 111351760 111351810chr9 130991079 130991129 chr9 135214605 135214655 chr12 7999618 7999668chr12 31945285 31945335 chr12 39575608 39575658 chr12 52320280 52320330chr12 52321612 52321662 chr12 100325057 100325107 chr12 111483638111483688 chr12 115418466 115418516 chr12 131850894 131850944 chr1317910936 17910986 chr13 39573871 39573921 chr13 60786063 60786113 chr1376746786 76746836 chr13 87557235 87557285 chr14 70028797 70028847 chr1471827127 71827177 chr14 79377960 79378010 chr14 84341952 84342002 chr1487918997 87919047 chr14 90393525 90393575 chr14 94832153 94832203 chr1498642422 98642472 chr14 98645152 98645202 chr14 100170221 100170271chr14 100170284 100170334 chr15 22095918 22095968 chr15 2238663422386684 chr10 63625136 63625186 chr10 63624530 63624580 chr15 6198877261988822 chr15 75075059 75075109 chr15 85849930 85849980 chr15 8584986385849913 chr15 87852749 87852799 chr15 98876768 98876818 chr15 9923659399236643 chr16 136066 136116 chr16 413009 413059 chr10 70280865 70280915chr16 2210094 2210144 chr16 9210344 9210394 chr16 12169904 12169954chr16 19879657 19879707 chr16 25794237 25794287 chr16 66343915 66343965chr16 75476527 75476577 chr16 75575684 75575734 chr16 83831461 83831511chr10 3319173 3319223 chr16 87359110 87359160 chr10 76012564 76012614chr10 76421584 76421634 chr17 7135486 7135536 chr17 7136669 7136719chr17 8642561 8642611 chr17 9920205 9920255 chr17 17739429 17739479chr17 20061485 20061535 chr17 30815617 30815667 Table 15DT. RepeatCategory MSTD chr17 43738723 43738773 chr17 45532986 45533036 chr1749348289 49348339 chr17 50076545 50076595 chr17 64354869 64354919 chr1770447280 70447330 chr10 91061511 91061561 chr17 79431375 79431425 chr1779431253 79431303 chr18 30045015 30045065 chr10 97806683 97806733 chr1858695927 58695977 chr18 70339103 70339153 chr19 1924561 1924611 chr196746974 6747024 chr19 18002336 18002386 chr19 41423915 41423965 chr1945017121 45017171 chr19 45017455 45017505 chr19 45459348 45459398 chr1952412887 52412937 chr19 52412992 52413042 chr19 52413861 52413911 chr1952447915 52447965 chr1 1066451 1066501 chr1 3743795 3743845 chr10116234529 116234579 chr1 7348055 7348105 chr1 16729622 16729672 chr120256799 20256849 chr1 23730576 23730626 chr1 30386744 30386794 chr131843743 31843793 chr1 39463055 39463105 chr1 42683834 42683884 chr145148590 45148640 chr1 47193023 47193073 chr1 65138075 65138125 chr10124312216 124312266 chr10 124314004 124314054 chr1 75888168 75888218chr1 80833521 80833571 chr1 82407150 82407200 chr1 99301370 99301420chr1 102470555 102470605 chr1 102829815 102829865 chr1 105056441105056491 chr1 141906328 141906378 chr1 141906931 141906981 chr1162897100 162897150 chr1 163667791 163667841 chr1 170627883 170627933chr1 170627498 170627548 chr1 173809339 173809389 chr1 176279453176279503 chr1 179647472 179647522 chr1 197716439 197716489 chr1214539452 214539502 chr1 239772333 239772383 chr10 132297213 132297263chr1 243449738 243449788 chr20 4030829 4030879 chr20 34729575 34729625chr20 53115309 53115359 chr20 54290571 54290621 chr20 55725553 55725603chr20 62858940 62858990 chr21 18106682 18106732 chr21 18418060 18418110chr21 24273192 24273242 chr21 35119635 35119685 chr21 35119017 35119067chr21 43466253 43466303 chr21 43714375 43714425 chr22 31779866 31779916chr22 37307168 37307218 chr22 43770699 43770749 chr22 47403855 47403905chr22 48220341 48220391 chrX 5462786 5462836 chrX 12142713 12142763 chrX23795630 23795680 chrX 24665184 24665234 chrX 30385238 30385288 chrX36851284 36851334 chrX 40037922 40037972 chrX 42899401 42899451 chrX47992094 47992144 chrX 54365148 54365198 chr11 8266660 8266710 chrX81777222 81777272 chrX 85708031 85708081 chrX 85714508 85714558 chrX93239943 93239993 chrX 93290733 93290783 chrX 114334364 114334414 chrX126583601 126583651 chrX 131058099 131058149 chrX 137638369 137638419chrX 137645373 137645423 chrX 139612067 139612117 chr11 1242379612423846 chrX 150782133 150782183 chrX 150782676 150782726 chrY 30247153024765 chrY 21815090 21815140 chr2 5620456 5620506 chr11 1717938817179438 chr2 16116695 16116745 chr2 19841006 19841056 chr2 2405752924057579 chr2 39073747 39073797 chr2 40153961 40154011 chr2 6389015363890203 chr2 65316675 65316725 chr2 70205880 70205930 chr11 2581447525814525 chr2 72079481 72079531 chr2 75499248 75499298 chr2 8305004083050090 chr2 85423647 85423697 chr2 91639134 91639184 chr11 2861072328610773 chr2 98778873 98778923 chr2 105590583 105590633 chr11 3169106431691114 chr2 109170435 109170485 chr2 113386749 113386799 chr2114666213 114666263 chr2 138570986 138571036 chr2 140775550 140775600chr2 149256417 149256467 chr2 171293511 171293561 chr2 172135643172135693 chr2 175674694 175674744 chr2 179296325 179296375 chr2182319616 182319666 chr2 186325045 186325095 chr2 193697445 193697495chr2 194128026 194128076 chr2 196564591 196564641 chr2 219300124219300174 chr2 232042152 232042202 chr2 241404409 241404459 chr2242786781 242786831 chr3 3676706 3676756 chr3 24001280 24001330 chr333397439 33397489 chr11 47749644 47749694 chr3 60980262 60980312 chr397520834 97520884 chr3 104227089 104227139 chr11 60127596 60127646 chr3132371115 132371165 chr3 134209206 134209256 chr3 148009254 148009304chr3 161218343 161218393 chr3 171217151 171217201 chr3 173356286173356336 chr3 173912627 173912677 chr3 178655690 178655740 chr1162262407 62262457 chr4 2806392 2806442 chr4 3722738 3722788 chr4 59004625900512 chr4 6662281 6662331 chr4 21267829 21267879 chr4 2880111528801165 chr4 38320725 38320775 chr4 65103738 65103788 chr4 6707232467072374 chr4 69226257 69226307 chr4 103542545 103542595 chr4 111032984111033034 chr4 111057630 111057680 chr4 111059573 111059623 chr4115757127 115757177 chr4 125274904 125274954 chr4 138040067 138040117chr4 140254634 140254684 chr4 146976983 146977033 chr4 149148078149148128 chr4 153514868 153514918 chr4 183461044 183461094 chr4183461165 183461215 chr4 183461415 183461465 chr4 184706031 184706081chr4 186732212 186732262 chr5 1615936 1615986 chr5 12822453 12822503chr5 15131992 15132042 chr5 21578232 21578282 chr5 22148192 22148242chr5 22632364 22632414 chr5 23559092 23559142 chr5 33331587 33331637chr5 58993631 58993681 chr5 64848896 64848946 chr5 66499603 66499653chr5 72899463 72899513 chr11 70960369 70960419 chr11 71022050 71022100chr5 126895014 126895064 chr5 131931958 131932008 chr11 7290754672907596 chr5 138360702 138360752 chr5 142886871 142886921 chr5148886376 148886426 chr5 157324900 157324950 chr5 157338016 157338066chr5 161079161 161079211 chr5 165621557 165621607 chr5 171447268171447318 chr5 173652167 173652217 chr6 7320875 7320925 chr6 1021522810215278 chr6 13678216 13678266 chr6 15609887 15609937 chr6 1745088017450930 chr6 23793761 23793811 chr6 30567379 30567429 chr6 3705833437058384 chr6 37127691 37127741 chr6 71774224 71774274 chr6 7235069472350744 chr6 80935768 80935818 chr6 107256215 107256265 chr6 110966109110966159 chr6 134445871 134445921 chr6 140025662 140025712 chr6142018072 142018122 chr6 144560003 144560053 chr6 153311845 153311895chr6 159933524 159933574 chr6 159933845 159933895 chr6 161256490161256540 chr6 162181882 162181932 chr6 170253920 170253970 chr6170322679 170322729 chr6 170322289 170322339 chr7 15934339 15934389 chr732872814 32872864 chr7 35094830 35094880 chr7 36533292 36533342 chr763899329 63899379 chr7 81779845 81779895 chr7 88609021 88609071 chr10971772 971822 chr11 117478034 117478084 chr7 129260636 129260686 chr7134646503 134646553 chr7 142192010 142192060 chr7 146308980 146309030chr7 148777194 148777244 chr7 149016006 149016056 chr8 13242512 13242562chr8 13686403 13686453 chr8 30242500 30242550 chr8 33549778 33549828chr8 58204850 58204900 chr11 125656200 125656250 chr8 81181083 81181133chr8 83159889 83159939 chr8 96317756 96317806 chr8 98175453 98175503chr8 103769219 103769269 chr10 18986048 18986098 chr8 117930368117930418 chr8 124068231 124068281 chr8 124147936 124147986 chr8124147788 124147838 chr8 126658306 126658356 chr8 142330104 142330154chr9 6236705 6236755 chr9 17091118 17091168 chr9 20251522 20251572 chr925389724 25389774 chr9 31262357 31262407 chr9 33197992 33198042 chr976776257 76776307 chr9 83972525 83972575 chr9 119232210 119232260 chr9123524649 123524699 chr9 128152483 128152533 chr9 129451181 129451231chr9 132293098 132293148 chr12 2958931 2958981 chr12 4378655 4378705chr12 6482883 6482933 chr12 14398174 14398224 chr12 17508576 17508626chr12 20300200 20300250 chr12 25028702 25028752 chr12 26943508 26943558chr12 43888213 43888263 chr12 50841873 50841923 chr10 27444500 27444550chr10 28117270 28117320 chr10 28808079 28808129 chr12 75813744 75813794chr12 100313075 100313125 chr12 105956867 105956917 chr12 118148833118148883 chr12 123110571 123110621 chr12 131133988 131134038 chr1318609269 18609319 chr13 23446581 23446631 chr10 36703731 36703781 chr1325863440 25863490 chr13 31402114 31402164 chr13 52707833 52707883 chr1361389286 61389336 chr13 73889015 73889065 chr13 79671458 79671508 chr13111562838 111562888 chr14 19251435 19251485 chr14 24114849 24114899chr14 35751436 35751486 chr14 43397426 43397476 chr14 43397944 43397994chr14 43397539 43397589 chr14 52928696 52928746 chr14 54246808 54246858chr14 56371593 56371643 chr14 59630337 59630387 chr10 51476484 51476534chr14 68218035 68218085 chr14 73918164 73918214 chr14 91213061 91213111chr14 100619643 100619693 chr14 101031609 101031659 chr14 103973354103973404 chr15 23066720 23066770 chr15 27248673 27248723 chr15 3323148333231533 chr15 43752861 43752911 chr15 48501306 48501356 chr15 5120086551200915 chr15 58424712 58424762 chr15 62949040 62949090 chr15 6495748564957535 chr15 72508130 72508180 chr15 81315284 81315334 chr15 8131478181314831 chr15 99264746 99264796 chr15 99264648 99264698 chr10 7028560770285657 chr16 7248087 7248137 chr10 3051755 3051805 chr10 7161656571616615 chr16 20906968 20907018 chr16 29063507 29063557 chr16 3567491435674964 chr16 68527548 68527598 chr16 69591980 69592030 chr16 7462845274628502 chr16 87776616 87776666 chr16 89880459 89880509 chr17 276139276189 chr17 552917 552967 chr17 16700384 16700434 chr17 1903079519030845 chr17 19762274 19762324 chr17 21559575 21559625 chr17 3081561730815667 Table 15DU. Repeat Category PABL_A chr17 72568231 72568281chr17 77261469 77261519 chr17 80981555 80981605 chr18 75923806 75923856chr10 99786992 99787042 chr19 19670682 19670732 chr19 34809321 34809371chr19 56442846 56442896 chr1 39801573 39801623 chr1 143790728 143790778chr1 231283070 231283120 chrX 2455769 2455819 chrX 6724490 6724540 chrX16108953 16109003 chrX 16112159 16112209 chrX 16588750 16588800 chrX68159818 68159868 chrX 109566684 109566734 chrX 109686451 109686501 chrX124825702 124825752 chrX 124829612 124829662 chrY 4927929 4927979 chr2133451 133501 chr2 30283438 30283488 chr2 127848432 127848482 chr2243070936 243070986 chr3 3144325 3144375 chr3 3144439 3144489 chr33145469 3145519 chr3 46960831 46960881 chr3 123509622 123509672 chr3129710293 129710343 chr4 142212094 142212144 chr4 164060926 164060976chr4 164061119 164061169 chr4 164061270 164061320 chr4 164061519164061569 chr11 71588207 71588257 chr6 107368702 107368752 chr1197480148 97480198 chr6 169495542 169495592 chr7 34532025 34532075 chr734533818 34533868 chr7 57345133 57345183 chr8 22932018 22932068 chr823119513 23119563 chr8 23121541 23121591 chr8 26089194 26089244 chr992370890 92370940 chr9 136045910 136045960 chr12 48662383 48662433 chr1251791449 51791499 chr13 21255392 21255442 chr13 48064778 48064828 chr1419468645 19468695 chr10 59239398 59239448 chr15 20006983 20007033 chr162249820 2249870 chr16 2252152 2252202 chr16 10342661 10342711 chr1612378743 12378793 chr16 84020451 84020501 Table 15DV. Repeat CategoryPABL_B chr10 85531577 85531627 chr18 46230633 46230683 chr18 6315127163151321 chr19 61162672 61162722 chr1 16907790 16907840 chr21 3370516833705218 chr22 48266608 48266658 chrX 2451150 2451200 chr11 56249055624955 chrX 92036559 92036609 chrX 95869474 95869524 chrX 9587375195873801 chrX 129543009 129543059 chrY 13469834 13469884 chr2 3019135130191401 chr2 54232197 54232247 chr3 42806657 42806707 chr3 4280741642807466 chr4 103542545 103542595 chr4 188045924 188045974 chr4188045864 188045914 chr6 26424403 26424453 chr6 32179199 32179249 chr653481562 53481612 chr11 107188156 107188206 chr7 4799187 4799237 chr7134425891 134425941 chr8 54315147 54315197 chr8 144252687 144252737 chr9133981791 133981841 chr9 133990061 133990111 chr9 133991258 133991308chr9 133994121 133994171 chr12 30563067 30563117 chr16 9305240 9305290chr17 11013127 11013177 Table 15DW. Repeat Category SST1 chr18 1117913611179186 chr19 41439574 41439624 chr19 41442157 41442207 chr19 4145094141450991 chr19 41454843 41454893 chr19 42190779 42190829 chr19 4219295642193006 chr19 42195250 42195300 chr19 42197755 42197805 chr19 4223852142238571 chr19 42240257 42240307 chr19 42241761 42241811 chr19 4224383042243880 chr19 42452388 42452438 chr19 42464712 42464762 chr19 4246749342467543 chr19 42487646 42487696 chr19 42732769 42732819 chr19 4273442042734470 chr19 42734152 42734202 chr20 25829405 25829455 chr20 2583232325832373 chr20 25834137 25834187 chr20 25834860 25834910 chr20 2583617825836228 chr20 25837963 25838013 chr20 25839822 25839872 chr20 2584151025841560 chr20 25843969 25844019 chr20 25960261 25960311 chr20 2596144525961495 chr20 25962189 25962239 chr20 25962783 25962833 chr20 2596395025964000 chr20 25965913 25965963 chr20 25967555 25967605 chr20 2622726326227313 chr20 29411493 29411543 chr20 29413930 29413980 chr20 2941447929414529 chr20 29416037 29416087 chr20 29465353 29465403 chr22 1560367715603727 chrY 8244873 8244923 chrY 8586928 8586978 chrY 8594455 8594505chrY 8599812 8599862 chrY 8802608 8802658 chrY 8832966 8833016 chrY22603191 22603241 chrY 22604888 22604938 chrY 22612413 22612463 chrY22811477 22811527 chrY 22816605 22816655 chrY 22816405 22816455 chr4133105673 133105723 chr4 133108807 133108857 chr4 133114432 133114482chr4 133119447 133119497 chr4 133121931 133121981 chr4 133128547133128597 chr4 133144611 133144661 chr4 133356425 133356475 chr6 25827612582811 chr6 2584919 2584969 chr6 2584618 2584668 chr7 57323292 57323342chr7 57484576 57484626 chr7 57489252 57489302 chr7 57491668 57491718chr7 57493544 57493594 chr7 57608476 57608526 chr7 57611298 57611348chr7 57612957 57613007 chr7 57614872 57614922 chr7 57657592 57657642chr7 57658603 57658653 chr7 57660994 57661044 chr7 63740873 63740923chr7 63742146 63742196 chr7 63742406 63742456 chr7 63743064 63743114chr7 63745004 63745054 chr7 63747477 63747527 chr7 63750110 63750160chr7 63752506 63752556 chr7 63755151 63755201 chr7 63754991 63755041chr7 63756844 63756894 chr9 42227834 42227884 chr9 42278036 42278086chr9 42279994 42280044 chr9 42281227 42281277 chr9 42282424 42282474chr9 42283864 42283914 chr9 42285059 42285109 chr9 42286324 42286374chr9 43656896 43656946 chr9 63427466 63427516 chr9 63959998 63960048chr9 64968296 64968346 chr12 36221876 36221926 chr12 36223975 36224025chr12 36226413 36226463 chr12 36227743 36227793 chr16 35295200 35295250chr16 35456280 35456330 chr16 35458498 35458548 chr16 36108845 36108895chr16 36111212 36111262 chr17 21639309 21639359 chr17 21639450 21639500chr17 21971245 21971295 chr17 21971093 21971143 chr17 21973380 21973430chr17 21975111 21975161 chr17 21976921 21976971 chr17 22047600 22047650chr17 22049889 22049939 chr17 22051925 22051975 chr17 22053384 22053434chr17 22054809 22054859 chr17 22056570 22056620 chr17 22337670 22337720chr17 25628588 25628638 chr17 25631116 25631166 Table 15DX. RepeatCategory SVA chr17 37864620 37864670 chr17 37868936 37868986 chr1081959991 81960041 chr17 41685175 41685225 chr17 42004319 42004369 chr1742734324 42734374 chr17 43076361 43076411 chr17 45948984 45949034 chr1747677535 47677585 chr17 47701957 47702007 chr17 47703054 47703104 chr1085605701 85605751 chr17 56397987 56398037 chr17 56627221 56627271 chr1756695603 56695653 chr17 56761362 56761412 chr17 59102423 59102473 chr1759104693 59104743 chr17 59528917 59528967 chr17 60573292 60573342 chr1762007246 62007296 chr17 64030006 64030056 chr17 64382861 64382911 chr1764482980 64483030 chr10 87878662 87878712 chr17 76370870 76370920 chr1777057926 77057976 chr17 77059787 77059837 chr17 78833919 78833969 chr1778920815 78920865 chr17 78921614 78921664 chr10 92748136 92748186 chr1781013243 81013293 chr18 9420600 9420650 chr18 10497097 10497147 chr1094398851 94398901 chr18 11598689 11598739 chr18 11604243 11604293 chr1811638686 11638736 chr18 12233072 12233122 chr18 12971495 12971545 chr1813089283 13089333 chr18 14002100 14002150 chr18 14844429 14844479 chr1816970446 16970496 chr10 95394816 95394866 chr18 28980431 28980481 chr1831910823 31910873 chr18 43605810 43605860 chr18 44859908 44859958 chr1097234931 97234981 chr18 45357576 45357626 chr18 45577496 45577546 chr1846197026 46197076 chr18 46387762 46387812 chr18 50122968 50123018 chr1860425731 60425781 chr18 62943894 62943944 chr10 98366801 98366851 chr1865919396 65919446 chr18 71840174 71840224 chr10 98954242 98954292 chr1099265275 99265325 chr10 99576058 99576108 chr19 3949538 3949588 chr10101516416 101516466 chr10 101700609 101700659 chr19 8710247 8710297chr19 10449737 10449787 chr19 11274598 11274648 chr19 11649906 11649956chr19 12333644 12333694 chr19 12438908 12438958 chr19 12594362 12594412chr19 13674463 13674513 chr19 15334075 15334125 chr19 17978509 17978559chr10 103726614 103726664 chr19 20036101 20036151 chr19 2010893220108982 chr19 20148629 20148679 chr19 20506124 20506174 chr19 2102351321023563 chr19 21188097 21188147 chr19 21234798 21234848 chr19 2123670021236750 chr19 21419107 21419157 chr19 21461933 21461983 chr19 2148700521487055 chr19 21582097 21582147 chr19 21589414 21589464 chr19 2168193821681988 chr19 21694870 21694920 chr19 21841739 21841789 chr19 2207930222079352 chr19 22083508 22083558 chr19 22296495 22296545 chr19 2267529422675344 chr19 22677851 22677901 chr19 22900009 22900059 chr19 2310896123109011 chr19 23136141 23136191 chr19 23147388 23147438 chr19 2326547323265523 chr19 23344675 23344725 chr19 23394402 23394452 chr19 2350837123508421 chr19 23911260 23911310 chr19 35131898 35131948 chr19 3926107439261124 chr19 39263427 39263477 chr19 39314605 39314655 chr19 4010406540104115 chr19 42870509 42870559 chr19 43305581 43305631 chr19 4354724643547296 chr19 43547461 43547511 chr19 43981578 43981628 chr19 4399027143990321 chr10 105032521 105032571 chr19 45307583 45307633 chr1945999128 45999178 chr19 46163266 46163316 chr19 46165258 46165308 chr1946377437 46377487 chr19 46964552 46964602 chr10 106209953 106210003chr19 47807284 47807334 chr19 47807539 47807589 chr19 47836528 47836578chr19 47836738 47836788 chr19 48743784 48743834 chr19 49684062 49684112chr10 112192597 112192647 chr19 55586783 55586833 chr19 5577774755777797 chr19 57147868 57147918 chr19 57217319 57217369 chr19 5787094257870992 chr19 57914686 57914736 chr19 58115312 58115362 chr19 5841713558417185 chr19 58464391 58464441 chr19 58465975 58466025 chr19 5878200758782057 chr19 59410613 59410663 chr10 6101851 6101901 chr19 6360964363609693 chr1 6075915 6075965 chr1 6485917 6485967 chr10 116211014116211064 chr1 7723387 7723437 chr1 8269871 8269921 chr1 8681661 8681711chr1 8682579 8682629 chr1 11076259 11076309 chr10 6253552 6253602 chr120820932 20820982 chr1 21297955 21298005 chr1 24478767 24478817 chr124509715 24509765 chr1 24512635 24512685 chr1 26528785 26528835 chr126750546 26750596 chr1 26994783 26994833 chr1 27786309 27786359 chr130321610 30321660 chr10 120686024 120686074 chr1 32941385 32941435 chr132942019 32942069 chr1 32944060 32944110 chr1 33325049 33325099 chr134050727 34050777 chr1 34840779 34840829 chr1 36972969 36973019 chr10121147198 121147248 chr1 38527309 38527359 chr1 39114566 39114616 chr139748084 39748134 chr1 39791216 39791266 chr10 121640164 121640214 chr144960171 44960221 chr1 44983957 44984007 chr1 44995084 44995134 chr145102917 45102967 chr1 45126460 45126510 chr1 45376458 45376508 chr145572936 45572986 chr1 46075784 46075834 chr1 48220000 48220050 chr148314226 48314276 chr1 50217707 50217757 chr1 50662437 50662487 chr150787686 50787736 chr1 51548093 51548143 chr1 52706478 52706528 chr154068147 54068197 chr10 123628332 123628382 chr1 76001630 76001680 chr177575987 77576037 chr1 77759401 77759451 chr1 80923529 80923579 chr186789105 86789155 chr1 86852333 86852383 chr1 89730933 89730983 chr191221796 91221846 chr1 91964013 91964063 chr1 91964210 91964260 chr196407451 96407501 chr1 96408015 96408065 chr1 96700970 96701020 chr198442195 98442245 chr1 98442407 98442457 chr1 99007962 99008012 chr199436588 99436638 chr1 99436839 99436889 chr1 99786467 99786517 chr1106309087 106309137 chr1 108058362 108058412 chr1 108426146 108426196chr1 108564251 108564301 chr1 111074871 111074921 chr1 111371416111371466 chr1 111450444 111450494 chr1 111641250 111641300 chr1112481075 112481125 chr1 112569776 112569826 chr1 112740854 112740904chr1 114084359 114084409 chr1 114321118 114321168 chr1 114646723114646773 chr1 115202666 115202716 chr1 117317734 117317784 chr1117320217 117320267 chr1 141723087 141723137 chr1 143416461 143416511chr1 143419906 143419956 chr1 144039781 144039831 chr1 146561408146561458 chr10 126780633 126780683 chr1 147918894 147918944 chr1148790802 148790852 chr1 148841397 148841447 chr1 148958259 148958309chr1 149267901 149267951 chr1 149334791 149334841 chr1 149385870149385920 chr1 149445795 149445845 chr1 149662123 149662173 chr10127233754 127233804 chr1 151477705 151477755 chr1 151568711 151568761chr1 152887053 152887103 chr1 153745730 153745780 chr1 156635625156635675 chr10 128266789 128266839 chr1 157717997 157718047 chr1158119199 158119249 chr1 158216159 158216209 chr1 158469005 158469055chr1 158608730 158608780 chr1 159608960 159609010 chr1 159614599159614649 chr1 159624064 159624114 chr1 160655110 160655160 chr1160656709 160656759 chr1 164186577 164186627 chr1 164928750 164928800chr1 164963491 164963541 chr1 165365335 165365385 chr1 165993319165993369 chr1 167576429 167576479 chr1 168902433 168902483 chr1169780288 169780338 chr1 171969996 171970046 chr1 173265792 173265842chr1 176249568 176249618 chr1 179647472 179647522 chr1 179951552179951602 chr1 180635497 180635547 chr1 183667543 183667593 chr1184823767 184823817 chr1 186397756 186397806 chr1 194662399 194662449chr1 195841881 195841931 chr1 199448114 199448164 chr1 199998056199998106 chr1 200524238 200524288 chr1 200987630 200987680 chr1206381019 206381069 chr1 208364987 208365037 chr1 208450031 208450081chr1 208712267 208712317 chr1 209527408 209527458 chr1 210008207210008257 chr1 210383109 210383159 chr1 212100487 212100537 chr1214754763 214754813 chr1 217697475 217697525 chr1 221512399 221512449chr1 222777223 222777273 chr1 222959363 222959413 chr1 224294417224294467 chr1 224874141 224874191 chr1 228624252 228624302 chr1229551038 229551088 chr1 229552484 229552534 chr1 231488680 231488730chr1 233632164 233632214 chr1 234332911 234332961 chr1 234873194234873244 chr1 235530678 235530728 chr1 238620763 238620813 chr1242885219 242885269 chr1 243473979 243474029 chr1 244141539 244141589chr1 244329852 244329902 chr1 244632046 244632096 chr1 245774636245774686 chr20 3102191 3102241 chr20 4007499 4007549 chr20 54284995428549 chr20 5615696 5615746 chr20 8619097 8619147 chr20 93611369361186 chr20 11489840 11489890 chr20 13735794 13735844 chr20 1620429316204343 chr20 19654518 19654568 chr10 133277383 133277433 chr2024600970 24601020 chr20 25287625 25287675 chr20 29422434 29422484 chr2031453944 31453994 chr20 31510455 31510505 chr20 32418550 32418600 chr2032489817 32489867 chr20 32841002 32841052 chr20 33002555 33002605 chr2033005345 33005395 chr20 36325661 36325711 chr20 36464063 36464113 chr2037694101 37694151 chr20 37694043 37694093 chr20 37826042 37826092 chr2040870445 40870495 chr20 42921658 42921708 chr20 44960382 44960432 chr2044961126 44961176 chr20 49225279 49225329 chr20 53551561 53551611 chr2057674894 57674944 chr21 15966999 15967049 chr21 17587571 17587621 chr2125989075 25989125 chr21 28857115 28857165 chr21 36684328 36684378 chr2137959115 37959165 chr21 46060422 46060472 chr10 8914307 8914357 chr2216899855 16899905 chr22 17263086 17263136 chr22 17445438 17445488 chr2220356744 20356794 chr22 21120114 21120164 chr22 22227124 22227174 chr2222786667 22786717 chr22 23039036 23039086 chr22 23999369 23999419 chr2227275106 27275156 chr10 9320215 9320265 chr22 28272240 28272290 chr2228364660 28364710 chr22 28780217 28780267 chr22 29746663 29746713 chr2229748744 29748794 chr22 29905657 29905707 chr22 33404992 33405042 chr2234959787 34959837 chr22 37620291 37620341 chr22 37620133 37620183 chr2237650110 37650160 chr10 9901903 9901953 chr22 39932992 39933042 chr2240271217 40271267 chr22 41599274 41599324 chr11 3383795 3383845 chr2248029596 48029646 chr22 48610304 48610354 chrX 6987354 6987404 chrX6989970 6990020 chrX 7881727 7881777 chr11 4123633 4123683 chrX 1299223012992280 chr11 4222421 4222471 chrX 16345668 16345718 chrX 1634921016349260 chrX 16625550 16625600 chrX 22902646 22902696 chrX 2408980724089857 chrX 25284717 25284767 chrX 26838354 26838404 chr11 59202755920325 chr11 5945739 5945789 chrX 28714872 28714922 chrX 3564055135640601 chrX 36598374 36598424 chrX 39753937 39753987 chrX 4027503140275081 chrX 41175076 41175126 chrX 41365260 41365310 chrX 4381552843815578 chrX 43947517 43947567 chrX 44410035 44410085 chrX 4530250245302552 chrX 47019969 47020019 chrX 49779322 49779372 chrX 5182364651823696 chrX 52714800 52714850 chrX 53208387 53208437 chrX 5372927353729323 chrX 54365148 54365198 chrX 54741759 54741809 chrX 5537373755373787 chrX 61277107 61277157 chrX 61913176 61913226 chrX 6406272964062779 chrX 66412501 66412551 chrX 66565428 66565478 chrX 6750865367508703 chr11 8508575 8508625 chrX 68209070 68209120 chrX 6843697568437025 chrX 68459317 68459367 chrX 68767264 68767314 chrX 6938724469387294 chrX 69386927 69386977 chrX 69732487 69732537 chrX 6976284469762894 chrX 70266731 70266781 chrX 70769609 70769659 chrX 7110743671107486 chrX 71109494 71109544 chrX 71153900 71153950 chrX 7196894471968994 chrX 72254796 72254846 chrX 72499987 72500037 chrX 7342041873420468 chrX 73422875 73422925 chrX 75153113 75153163 chrX 7536728775367337 chr11 8963146 8963196 chrX 75944307 75944357 chrX 7840929678409346 chrX 78723449 78723499 chrX 85060151 85060201 chrX 8549263085492680 chrX 94078171 94078221 chrX 98749981 98750031 chrX 9900033699000386 chrX 99766108 99766158 chrX 120487623 120487673 chrX 121419432121419482 chrX 121565043 121565093 chrX 121960814 121960864 chrX124480096 124480146 chrX 124514656 124514706 chrX 129166861 129166911chrX 132126485 132126535 chrX 132799266 132799316 chrX 134789452134789502 chrX 136071210 136071260 chrX 143798909 143798959 chrX145741311 145741361 chrX 149386401 149386451 chrX 152469870 152469920chrX 152875190 152875240 chrY 3866599 3866649 chrY 8489041 8489091 chrY13574876 13574926 chrY 13999269 13999319 chrY 20592134 20592184 chrY21559578 21559628 chr2 117882 117932 chr11 15672337 15672387 chr23204573 3204623 chr2 4979181 4979231 chr2 7499488 7499538 chr11 1703750617037556 chr2 11066028 11066078 chr2 15382130 15382180 chr2 1577510215775152 chr2 15841628 15841678 chr11 18108009 18108059 chr2 2459812924598179 chr2 25732866 25732916 chr2 25734107 25734157 chr2 2583052525830575 chr2 25919797 25919847 chr2 26569299 26569349 chr2 2686309626863146 chr2 27738824 27738874 chr2 27756436 27756486 chr2 2779252927792579 chr2 32648272 32648322 chr2 32955231 32955281 chr2 3396164133961691 chr2 34333508 34333558 chr2 38135630 38135680 chr2 3816591538165965 chr2 38179276 38179326 chr11 19847158 19847208 chr2 3983091039830960 chr2 41947661 41947711 chr2 41950404 41950454 chr2 4219647242196522 chr2 42217298 42217348 chr2 42808785 42808835 chr2 4326584543265895 chr2 43498271 43498321 chr2 43500315 43500365 chr2 4388043043880480 chr2 44263336 44263386 chr2 44791739 44791789 chr11 2084997820850028 chr2 47636478 47636528 chr2 48756212 48756262 chr2 4881533848815388 chr2 50614095 50614145 chr2 53525354 53525404 chr2 5590729355907343 chr2 55976416 55976466 chr2 62832413 62832463 chr2 6392504263925092 chr2 64011757 64011807 chr2 64242968 64243018 chr2 6471383464713884 chr2 65803506 65803556 chr2 74263993 74264043 chr2 7432517774325227 chr2 75927671 75927721 chr2 86548260 86548310 chr2 8674803586748085 chr2 86751223 86751273 chr11 28415051 28415101 chr2 8912808189128131 chr2 95393385 95393435 chr2 98340411 98340461 chr2 105488366105488416 chr2 108965316 108965366 chr2 110558671 110558721 chr2113949003 113949053 chr2 120698151 120698201 chr2 126130693 126130743chr2 127971499 127971549 chr2 128203487 128203537 chr2 129058858129058908 chr2 129270462 129270512 chr2 130659025 130659075 chr2130683880 130683930 chr2 135032003 135032053 chr2 135936087 135936137chr2 136243700 136243750 chr2 136675380 136675430 chr11 3397188933971939 chr2 144959683 144959733 chr2 152935240 152935290 chr2153218611 153218661 chr2 157351779 157351829 chr2 157511773 157511823chr2 159370579 159370629 chr2 161499322 161499372 chr2 163528626163528676 chr2 170385154 170385204 chr2 170387761 170387811 chr2170563960 170564010 chr2 170565362 170565412 chr2 170635216 170635266chr2 171208056 171208106 chr2 172834746 172834796 chr2 172833072172833122 chr2 172960183 172960233 chr2 173604336 173604386 chr2173767165 173767215 chr2 176174649 176174699 chr2 178913322 178913372chr11 37418083 37418133 chr2 183453258 183453308 chr2 187222385187222435 chr2 188705461 188705511 chr2 190720813 190720863 chr2191499257 191499307 chr2 192466848 192466898 chr2 192808333 192808383chr2 193960514 193960564 chr2 198764906 198764956 chr2 198989211198989261 chr2 198991529 198991579 chr2 201752061 201752111 chr2202109174 202109224 chr2 202233824 202233874 chr2 202349139 202349189chr2 202630818 202630868 chr2 203601228 203601278 chr2 203783341203783391 chr2 204439048 204439098 chr11 41288808 41288858 chr2207425287 207425337 chr2 207467114 207467164 chr2 209445754 209445804chr2 212017257 212017307 chr2 217295015 217295065 chr2 220819339220819389 chr2 222958714 222958764 chr2 223884739 223884789 chr2230809338 230809388 chr2 233974469 233974519 chr2 234920756 234920806chr10 12273291 12273341 chr2 240172343 240172393 chr2 240582472240582522 chr2 243320065 243320115 chr3 2933957 2934007 chr3 51305705130620 chr3 5260197 5260247 chr3 5300631 5300681 chr3 8342595 8342645chr3 8457932 8457982 chr3 9575852 9575902 chr3 9587518 9587568 chr1146884329 46884379 chr3 10087134 10087184 chr3 10433363 10433413 chr1147082844 47082894 chr3 11504319 11504369 chr3 12865423 12865473 chr315077438 15077488 chr3 15178450 15178500 chr3 15758154 15758204 chr316013215 16013265 chr3 16997646 16997696 chr3 20565198 20565248 chr323889024 23889074 chr3 32182170 32182220 chr3 38054848 38054898 chr338067523 38067573 chr11 47877944 47877994 chr3 39229007 39229057 chr339657831 39657881 chr3 41307227 41307277 chr3 41843453 41843503 chr341985386 41985436 chr3 42798928 42798978 chr3 42912502 42912552 chr1148942104 48942154 chr3 44824130 44824180 chr3 47259349 47259399 chr347311155 47311205 chr11 50048250 50048300 chr3 50082426 50082476 chr1155687513 55687563 chr3 50800243 50800293 chr3 51244702 51244752 chr351304612 51304662 chr3 51601378 51601428 chr11 56039982 56040032 chr356576597 56576647 chr3 57330787 57330837 chr3 57689952 57690002 chr358233798 58233848 chr3 58834519 58834569 chr10 12566958 12567008 chr360870782 60870832 chr3 61336734 61336784 chr10 12569773 12569823 chr361378741 61378791 chr3 61613918 61613968 chr11 57260710 57260760 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64033294 64033344 chr10 6405350064053550 chr15 40609868 40609918 chr15 41176502 41176552 chr15 4330239843302448 chr15 44107034 44107084 chr15 47559523 47559573 chr15 4818221848182268 chr15 49893233 49893283 chr15 50468909 50468959 chr15 5279041252790462 chr15 53453930 53453980 chr10 64915612 64915662 chr10 6491606864916118 chr10 64916861 64916911 chr15 54549117 54549167 chr15 6022720060227250 chr15 60341617 60341667 chr10 66155772 66155822 chr10 6615593266155982 chr15 60699306 60699356 chr15 61106455 61106505 chr15 6614165766141707 chr15 66866763 66866813 chr15 66869293 66869343 chr15 6697381166973861 chr15 68880567 68880617 chr10 68795183 68795233 chr15 6977694569776995 chr15 72738079 72738129 chr15 73488837 73488887 chr15 7865589278655942 chr10 69383639 69383689 chr15 82211845 82211895 chr15 8294501982945069 chr10 2803222 2803272 chr15 86798037 86798087 chr15 8812649388126543 chr15 88139945 88139995 chr15 88142660 88142710 chr15 9088064890880698 chr15 91042469 91042519 chr15 99050468 99050518 chr16 15886421588692 chr16 2210094 2210144 chr16 2390927 2390977 chr16 28531592853209 chr16 3321835 3321885 chr10 71098249 71098299 chr10 7109847671098526 chr16 7952462 7952512 chr16 9411886 9411936 chr16 1139634911396399 chr16 13949321 13949371 chr10 71512902 71512952 chr16 1459384214593892 chr10 71734796 71734846 chr10 71793315 71793365 chr10 7179342171793471 chr16 30216836 30216886 chr16 31150915 31150965 chr16 3115320831153258 chr16 31279128 31279178 chr16 31883300 31883350 chr16 4646916346469213 chr16 46509889 46509939 chr16 46814287 46814337 chr16 4787145147871501 chr16 48227930 48227980 chr16 48295737 48295787 chr16 4876292648762976 chr16 49023177 49023227 chr10 72981158 72981208 chr10 7298130372981353 chr16 53350948 53350998 chr16 53437819 53437869 chr16 5351093053510980 chr16 53512182 53512232 chr16 55799000 55799050 chr16 5655032556550375 chr16 57011286 57011336 chr16 58207131 58207181 chr16 5865637258656422 chr16 60167127 60167177 chr16 66324250 66324300 chr16 6797456267974612 chr16 69861995 69862045 chr16 71398847 71398897 chr16 7230683272306882 chr16 76313675 76313725 chr16 80058285 80058335 chr10 7482005874820108 chr16 89272919 89272969 chr17 1800608 1800658 chr17 26160892616139 chr17 3221653 3221703 chr17 3482778 3482828 chr10 7643859476438644 chr10 76855725 76855775 chr17 5825875 5825925 chr17 84769468476996 chr17 8655083 8655133 chr17 10160440 10160490 chr17 1377022613770276 chr17 16084032 16084082 chr10 79180836 79180886 chr17 1899270518992755 chr10 79574109 79574159 chr17 19694535 19694585 chr17 1975015819750208 chr17 20623429 20623479 chr17 21049199 21049249 chr17 2568385825683908 chr17 26929269 26929319 chr17 27077855 27077905 chr17 2713270727132757 chr17 28005198 28005248 chr17 28996952 28997002 chr17 2899525728995307 chr17 29009873 29009923 chr17 29209120 29209170 chr17 2945393729453987 chr10 80384278 80384328 chr17 31396394 31396444 chr17 3366887833668928 chr17 36120972 36121022 chr17 37161394 37161444 chr17 3746247637462526 Table 15DY. Repeat Category K.standard.SVA_A chr17 5676136256761412 chr18 9420600 9420650 chr18 10497097 10497147 chr18 1160424311604293 chr18 11638686 11638736 chr18 12233072 12233122 chr18 1421191214211962 chr18 16970446 16970496 chr10 97234931 97234981 chr18 4619702646197076 chr18 65919396 65919446 chr10 101265324 101265374 chr1921234798 21234848 chr19 21236700 21236750 chr19 35085381 35085431 chr1943990271 43990321 chr19 50840274 50840324 chr19 55777747 55777797 chr1957914686 57914736 chr1 30321610 30321660 chr1 33018906 33018956 chr139879966 39880016 chr1 44983957 44984007 chr1 45572936 45572986 chr146075784 46075834 chr1 99436588 99436638 chr1 99436839 99436889 chr1112569776 112569826 chr1 114084359 114084409 chr1 115199896 115199946chr1 141723087 141723137 chr1 149267901 149267951 chr1 151568711151568761 chr1 157717997 157718047 chr1 159608960 159609010 chr1160655110 160655160 chr1 160656709 160656759 chr1 164928750 164928800chr1 164963491 164963541 chr1 171969996 171970046 chr1 180635497180635547 chr1 184823767 184823817 chr1 195841881 195841931 chr1222959363 222959413 chr1 235530678 235530728 chr20 3102191 3102241 chr209361136 9361186 chr21 14227516 14227566 chr21 15966999 15967049 chr2118015648 18015698 chr21 29684534 29684584 chr11 508667 508717 chr2237620291 37620341 chr22 37620133 37620183 chr22 37650110 37650160 chr2248610304 48610354 chrX 22902646 22902696 chrX 26838354 26838404 chrX54365148 54365198 chrX 68436975 68437025 chrX 69387244 69387294 chrX69386927 69386977 chrX 69761106 69761156 chrX 69762844 69762894 chrX71107436 71107486 chrX 71109494 71109544 chrX 73420418 73420468 chrX73422875 73422925 chrX 75153113 75153163 chrX 99766108 99766158 chrX120487623 120487673 chrX 131324699 131324749 chrY 13574876 13574926 chrY21559578 21559628 chr2 24598129 24598179 chr2 25732866 25732916 chr225734107 25734157 chr2 27792529 27792579 chr2 44263336 44263386 chr286548260 86548310 chr2 86748035 86748085 chr2 86751223 86751273 chr298340411 98340461 chr2 170387761 170387811 chr11 37418083 37418133 chr2188705461 188705511 chr2 204134699 204134749 chr2 232605106 232605156chr2 243320065 243320115 chr3 41843453 41843503 chr3 72058973 72059023chr3 75369099 75369149 chr3 95084603 95084653 chr3 102591681 102591731chr3 158218436 158218486 chr4 305760 305810 chr4 28268326 28268376 chr441408307 41408357 chr4 41409959 41410009 chr4 45126888 45126938 chr468249466 68249516 chr4 92548149 92548199 chr4 99710973 99711023 chr4106881271 106881321 chr4 111057630 111057680 chr4 111059573 111059623chr4 160257882 160257932 chr5 32085228 32085278 chr5 32088284 32088334chr5 37565317 37565367 chr11 70029414 70029464 chr5 49919632 49919682chr5 50087211 50087261 chr5 56830192 56830242 chr5 57876806 57876856chr5 63537275 63537325 chr5 74991734 74991784 chr5 77140242 77140292chr5 82817681 82817731 chr5 100198261 100198311 chr5 133269558 133269608chr11 78316902 78316952 chr6 30296612 30296662 chr6 33372672 33372722chr6 57222629 57222679 chr6 63870774 63870824 chr6 69827387 69827437chr6 70137007 70137057 chr6 70139399 70139449 chr6 158678351 158678401chr6 170013381 170013431 chr7 6007030 6007080 chr7 25957311 25957361chr7 25959456 25959506 chr11 111614658 111614708 chr7 30935952 30936002chr7 33086237 33086287 chr11 112931818 112931868 chr7 44652531 44652581chr7 54252876 54252926 chr7 66959479 66959529 chr7 76778790 76778840chr7 91129839 91129889 chr7 91267518 91267568 chr7 94090765 94090815chr7 96401185 96401235 chr7 99736285 99736335 chr7 102270270 102270320chr7 115832583 115832633 chr7 128409087 128409137 chr7 128410119128410169 chr7 128856947 128856997 chr7 138323984 138324034 chr7138325521 138325571 chr7 154279852 154279902 chr10 17678461 17678511chr8 48066608 48066658 chr8 53536435 53536485 chr8 55049110 55049160chr8 63357664 63357714 chr8 70817719 70817769 chr8 94802987 94803037chr8 98809396 98809446 chr8 118395610 118395660 chr9 5422566 5422616chr9 5424193 5424243 chr9 26482072 26482122 chr9 28140416 28140466 chr935173889 35173939 chr9 35174621 35174671 chr9 67871577 67871627 chr990209393 90209443 chr9 96605676 96605726 chr9 96605872 96605922 chr998533965 98534015 chr9 98534277 98534327 chr9 98534441 98534491 chr9102377741 102377791 chr9 102458408 102458458 chr9 132324195 132324245chr12 11502542 11502592 chr12 40906831 40906881 chr12 44265768 44265818chr12 44681193 44681243 chr12 47322573 47322623 chr12 47525993 47526043chr12 60690212 60690262 chr12 60691842 60691892 chr12 64840874 64840924chr12 64841114 64841164 chr12 64854457 64854507 chr12 68486670 68486720chr12 100986007 100986057 chr10 31655050 31655100 chr12 119127047119127097 chr12 119128750 119128800 chr12 119129274 119129324 chr1032800211 32800261 chr13 17206811 17206861 chr10 35655860 35655910 chr1340848367 40848417 chr13 41788073 41788123 chr13 76031516 76031566 chr1043021917 43021967 chr13 88282518 88282568 chr13 96125101 96125151 chr1045125753 45125803 chr10 45127879 45127929 chr14 20559441 20559491 chr1421567514 21567564 chr14 44094152 44094202 chr14 44094745 44094795 chr1449823063 49823113 chr14 64172573 64172623 chr14 90644482 90644532 chr1059348591 59348641 chr14 103553155 103553205 chr10 64033294 64033344chr15 53453930 53453980 chr15 54549117 54549167 chr16 2212473 2212523chr16 2213402 2213452 chr16 2214399 2214449 chr16 2216275 2216325 chr169411886 9411936 chr10 71345498 71345548 chr16 47871451 47871501 chr1655799000 55799050 chr16 60167127 60167177 chr17 8480455 8480505 chr1713770226 13770276 chr17 27132707 27132757 Table 15DZ. Repeat CategoryK.standard.SVA_B chr17 37864620 37864670 chr10 85605701 85605751 chr1756397987 56398037 chr17 59528917 59528967 chr17 64382861 64382911 chr1087878662 87878712 chr17 81411705 81411755 chr18 28980431 28980481 chr1843605810 43605860 chr18 46387762 46387812 chr18 74933112 74933162 chr1911649906 11649956 chr19 12333644 12333694 chr10 103726614 103726664chr19 21023513 21023563 chr19 21188097 21188147 chr19 21419107 21419157chr19 21589414 21589464 chr19 22296495 22296545 chr19 22675294 22675344chr19 22677851 22677901 chr19 22900009 22900059 chr19 23136141 23136191chr19 23265473 23265523 chr19 49398958 49399008 chr19 55586783 55586833chr19 60112838 60112888 chr1 32774148 32774198 chr1 33325049 33325099chr1 34050727 34050777 chr1 34840779 34840829 chr1 39748084 39748134chr1 44995084 44995134 chr1 45126460 45126510 chr1 45602161 45602211chr1 50787686 50787736 chr1 80923529 80923579 chr1 91221796 91221846chr1 91964013 91964063 chr1 91964210 91964260 chr1 91964585 91964635chr1 117190189 117190239 chr1 144039781 144039831 chr1 148958259148958309 chr1 149334791 149334841 chr10 127233754 127233804 chr10128266789 128266839 chr1 158119199 158119249 chr1 158216159 158216209chr1 160702335 160702385 chr1 164186577 164186627 chr1 165993319165993369 chr1 186397756 186397806 chr1 200524238 200524288 chr1200525208 200525258 chr1 200987630 200987680 chr1 209243993 209244043chr1 221512399 221512449 chr1 222777223 222777273 chr1 228624252228624302 chr1 233632164 233632214 chr1 242885219 242885269 chr2036464063 36464113 chr20 37826042 37826092 chr21 25989075 25989125 chr2136684328 36684378 chr21 44096750 44096800 chr10 9320215 9320265 chr2229905657 29905707 chr10 9901903 9901953 chr22 41235579 41235629 chr2241599274 41599324 chrX 12992230 12992280 chr11 4222421 4222471 chr114322037 4322087 chrX 25284717 25284767 chr11 5945739 5945789 chrX44410035 44410085 chrX 49779322 49779372 chrX 52714800 52714850 chrX53208387 53208437 chrX 53729273 53729323 chrX 61913176 61913226 chrX64062729 64062779 chrX 67508653 67508703 chr11 8508575 8508625 chrX68209070 68209120 chrX 69732487 69732537 chrX 71968944 71968994 chrX85060151 85060201 chrX 132126485 132126535 chrX 136071210 136071260 chrX143798909 143798959 chrX 149386401 149386451 chrX 152875190 152875240chrY 3866599 3866649 chrY 20592134 20592184 chr11 15672337 15672387 chr226863096 26863146 chr2 34333508 34333558 chr2 38179276 38179326 chr250614095 50614145 chr2 70469813 70469863 chr2 74325177 74325227 chr289122948 89122998 chr11 31957916 31957966 chr2 110558671 110558721 chr2126130693 126130743 chr2 130659025 130659075 chr2 136243700 136243750chr2 159370579 159370629 chr2 173767165 173767215 chr2 190720813190720863 chr2 193960514 193960564 chr2 202109174 202109224 chr2216231881 216231931 chr2 220819339 220819389 chr10 12273291 12273341chr2 240172343 240172393 chr3 2933957 2934007 chr3 5260197 5260247 chr316013215 16013265 chr3 20565198 20565248 chr3 38054848 38054898 chr338067523 38067573 chr11 47877944 47877994 chr3 39657831 39657881 chr342912502 42912552 chr11 48942104 48942154 chr3 50800243 50800293 chr351601378 51601428 chr11 56039982 56040032 chr3 60870782 60870832 chr361336734 61336784 chr11 57487558 57487608 chr3 98521242 98521292 chr1160052632 60052682 chr3 114497959 114498009 chr3 117558333 117558383 chr3120282325 120282375 chr3 128333637 128333687 chr3 128349536 128349586chr3 139561450 139561500 chr3 139825401 139825451 chr3 165822502165822552 chr3 176126000 176126050 chr3 180070735 180070785 chr3192163079 192163129 chr4 3127986 3128036 chr4 6903951 6904001 chr425002162 25002212 chr4 37406979 37407029 chr4 48104192 48104242 chr453774448 53774498 chr4 53922258 53922308 chr4 71218992 71219042 chr479387535 79387585 chr4 80625236 80625286 chr4 83456560 83456610 chr4107701499 107701549 chr4 110983061 110983111 chr4 115175721 115175771chr4 122617937 122617987 chr4 152452363 152452413 chr4 152463170152463220 chr4 153229381 153229431 chr4 154264872 154264922 chr4159137232 159137282 chr4 171296972 171297022 chr4 171446308 171446358chr4 171784156 171784206 chr4 174800413 174800463 chr5 43712487 43712537chr5 43792676 43792726 chr5 43869392 43869442 chr5 55570573 55570623chr5 55710450 55710500 chr5 75931791 75931841 chr5 93396334 93396384chr5 109245612 109245662 chr5 111772160 111772210 chr5 119558610119558660 chr11 73765747 73765797 chr5 156347832 156347882 chr5157443683 157443733 chr5 157445895 157445945 chr5 162992490 162992540chr11 74815284 74815334 chr6 13241543 13241593 chr11 78936415 78936465chr6 24522959 24523009 chr6 25695119 25695169 chr6 27605851 27605901chr6 28578886 28578936 chr6 31142316 31142366 chr6 31401822 31401872chr6 31927680 31927730 chr6 40830583 40830633 chr6 42702506 42702556chr6 47459498 47459548 chr6 57959000 57959050 chr6 58563155 58563205chr6 70671601 70671651 chr6 74631362 74631412 chr6 114298275 114298325chr6 122031226 122031276 chr11 98179198 98179248 chr6 144772891144772941 chr6 159737485 159737535 chr6 159738545 159738595 chr7 19450441945094 chr11 108553805 108553855 chr7 27770474 27770524 chr7 3253676632536816 chr7 44773074 44773124 chr7 47701973 47702023 chr7 7678025476780304 chr7 91785287 91785337 chr7 103911520 103911570 chr7 107456084107456134 chr7 127656826 127656876 chr11 118400170 118400220 chr7137478490 137478540 chr7 141724082 141724132 chr7 148422005 148422055chr8 15314670 15314720 chr8 21824766 21824816 chr8 24982546 24982596chr8 34810262 34810312 chr8 39214928 39214978 chr8 40372107 40372157chr8 40890180 40890230 chr8 42792417 42792467 chr8 50004901 50004951chr8 59740450 59740500 chr8 74807040 74807090 chr8 87359490 87359540chr8 90279395 90279445 chr8 94939631 94939681 chr8 99021152 99021202chr8 101321606 101321656 chr11 128537274 128537324 chr8 117267367117267417 chr8 118745802 118745852 chr8 143972289 143972339 chr915433194 15433244 chr9 26205941 26205991 chr9 26654616 26654666 chr927332388 27332438 chr9 75776286 75776336 chr9 94858637 94858687 chr994858981 94859031 chr9 94859352 94859402 chr9 95641048 95641098 chr995641130 95641180 chr9 100745241 100745291 chr9 100746438 100746488 chr9102631264 102631314 chr9 116817455 116817505 chr9 118775000 118775050chr9 132283480 132283530 chr12 12663361 12663411 chr12 24718263 24718313chr12 41031030 41031080 chr12 45850566 45850616 chr12 54329295 54329345chr12 55560307 55560357 chr12 56176032 56176082 chr12 56176903 56176953chr12 68056520 68056570 chr12 68534826 68534876 chr12 73269005 73269055chr10 29065758 29065808 chr12 101147487 101147537 chr12 107316726107316776 chr12 116581655 116581705 chr10 32271413 32271463 chr12119130771 119130821 chr10 32525560 32525610 chr10 32793443 32793493chr10 34645164 34645214 chr10 35269148 35269198 chr13 31094474 31094524chr13 31614992 31615042 chr13 34340336 34340386 chr13 36736001 36736051chr13 39943337 39943387 chr13 39945132 39945182 chr13 51191001 51191051chr13 74667316 74667366 chr13 83712078 83712128 chr13 85911036 85911086chr13 94196148 94196198 chr13 94279680 94279730 chr10 43226578 43226628chr10 43227149 43227199 chr10 43227801 43227851 chr14 18901435 18901485chr14 20156340 20156390 chr14 22195455 22195505 chr14 22358544 22358594chr14 30018612 30018662 chr14 30587748 30587798 chr14 32444317 32444367chr14 49414281 49414331 chr14 49415032 49415082 chr14 49924157 49924207chr14 54376795 54376845 chr10 51461449 51461499 chr14 69834765 69834815chr14 76204463 76204513 chr14 79701595 79701645 chr14 79919736 79919786chr15 40609868 40609918 chr15 44107034 44107084 chr15 49893233 49893283chr15 50468909 50468959 chr15 52790412 52790462 chr15 68880567 68880617chr15 78655892 78655942 chr15 86798037 86798087 chr16 13949321 13949371chr16 16677540 16677590 chr16 48227930 48227980 chr16 48295737 48295787chr16 53437819 53437869 chr16 66324250 66324300 chr16 76313675 76313725chr10 74820058 74820108 chr10 76855725 76855775 chr10 76856010 76856060chr17 8476946 8476996 chr17 8479472 8479522 chr10 79180836 79180886chr17 20623429 20623479 chr10 80384278 80384328 Table 15EA. RepeatCategory K.standard.SVA_C chr17 41685175 41685225 chr17 6671111966711169 chr18 11598689 11598739 chr18 66387013 66387063 chr19 2168193821681988 chr19 22079302 22079352 chr19 23394402 23394452 chr19 2350837123508421 chr19 23937139 23937189 chr19 35131898 35131948 chr19 4783652847836578 chr19 47836738 47836788 chr19 48743784 48743834 chr19 6268738762687437 chr1 11076259 11076309 chr1 21297955 21298005 chr10 120985417120985467 chr1 86852333 86852383 chr1 99007962 99008012 chr1 9900833999008389 chr1 99786467 99786517 chr1 114321118 114321168 chr1 114646723114646773 chr1 143419906 143419956 chr1 156635625 156635675 chr1165365335 165365385 chr1 168902433 168902483 chr1 177918084 177918134chr1 244632046 244632096 chr20 5615696 5615746 chr20 8619097 8619147chr20 11489840 11489890 chr20 18350266 18350316 chr20 32693778 32693828chr22 20356744 20356794 chr22 28272240 28272290 chr22 29354386 29354436chrX 13681062 13681112 chrX 16625550 16625600 chrX 35640551 35640601chrX 43815528 43815578 chrX 55373737 55373787 chrX 72499987 72500037chrX 85492630 85492680 chrX 124514656 124514706 chr2 33961641 33961691chr2 38165915 38165965 chr2 53525354 53525404 chr2 62832413 62832463chr2 183453258 183453308 chr2 202233824 202233874 chr2 209445754209445804 chr2 212017257 212017307 chr2 219417030 219417080 chr3 83425958342645 chr3 41985386 41985436 chr3 47311155 47311205 chr11 4978541249785462 chr11 50048250 50048300 chr3 56576597 56576647 chr3 8488826784888317 chr11 60033074 60033124 chr11 60033643 60033693 chr3 129812448129812498 chr3 138911732 138911782 chr3 142070326 142070376 chr3144113304 144113354 chr3 147134224 147134274 chr3 150483743 150483793chr3 157001239 157001289 chr3 178452418 178452468 chr3 197299068197299118 chr4 13514780 13514830 chr4 48210433 48210483 chr4 140238915140238965 chr4 160380069 160380119 chr4 160381966 160382016 chr4160382612 160382662 chr11 67141506 67141556 chr4 176203954 176204004chr4 185436887 185436937 chr11 68019296 68019346 chr5 43556883 43556933chr5 45936559 45936609 chr5 53733108 53733158 chr5 65270541 65270591chr5 80204338 80204388 chr5 105270759 105270809 chr5 117693901 117693951chr5 118376343 118376393 chr5 134821989 134822039 chr5 138525334138525384 chr5 151122935 151122985 chr5 151888965 151889015 chr1176021087 76021137 chr6 29969993 29970043 chr6 32005671 32005721 chr1185292010 85292060 chr11 85292396 85292446 chr11 86208950 86209000 chr643439030 43439080 chr6 50825357 50825407 chr6 58630865 58630915 chr666803405 66803455 chr6 74960358 74960408 chr6 86486068 86486118 chr687943856 87943906 chr6 88442417 88442467 chr6 105483836 105483886 chr6111384995 111385045 chr6 118115817 118115867 chr6 129389416 129389466chr6 140676975 140677025 chr6 165067882 165067932 chr6 165068088165068138 chr7 5519695 5519745 chr7 76778003 76778053 chr7 107050030107050080 chr7 111898941 111898991 chr7 127882691 127882741 chr7128668004 128668054 chr7 139221997 139222047 chr7 154218861 154218911chr8 913745 913795 chr8 11226468 11226518 chr11 123811680 123811730 chr852681243 52681293 chr8 66578304 66578354 chr8 68130536 68130586 chr887392904 87392954 chr8 100896929 100896979 chr9 6939844 6939894 chr933656621 33656671 chr9 34030443 34030493 chr9 37881172 37881222 chr9103017608 103017658 chr9 109760450 109760500 chr12 4669323 4669373 chr126455793 6455843 chr12 14398174 14398224 chr12 24971168 24971218 chr1233068276 33068326 chr12 37009491 37009541 chr12 39034079 39034129 chr1247201642 47201692 chr12 68438754 68438804 chr10 29227381 29227431 chr1288400938 88400988 chr12 107551344 107551394 chr12 123891250 123891300chr13 44535964 44536014 chr13 48133222 48133272 chr13 79518935 79518985chr14 33612065 33612115 chr14 37745688 37745738 chr14 43059916 43059966chr14 62640744 62640794 chr14 64150557 64150607 chr14 68359326 68359376chr14 68933729 68933779 chr14 82555168 82555218 chr15 18664321 18664371chr10 66155260 66155310 chr10 66155446 66155496 chr10 66155772 66155822chr10 66155932 66155982 chr10 68794843 68794893 chr16 17567629 17567679chr16 31154953 31155003 chr17 10160440 10160490 chr17 16417159 16417209chr17 29009873 29009923 chr17 33668878 33668928 Table 15EB. RepeatCategory K.standard.SVA_D chr17 37868936 37868986 chr10 8195999181960041 chr10 81960244 81960294 chr10 81960665 81960715 chr10 8196094481960994 chr17 42004319 42004369 chr17 43076361 43076411 chr17 4480435944804409 chr17 45948984 45949034 chr17 56627221 56627271 chr17 5669560356695653 chr17 57947352 57947402 chr17 60573292 60573342 chr17 6200724662007296 chr17 64030006 64030056 chr17 78921614 78921664 chr17 7921001879210068 chr17 79212344 79212394 chr10 92748136 92748186 chr18 68186876818737 chr18 9013011 9013061 chr10 94398851 94398901 chr18 1297149512971545 chr18 13089283 13089333 chr18 14002100 14002150 chr18 1437396814374018 chr18 31910823 31910873 chr18 44859908 44859958 chr18 5345075253450802 chr18 60425731 60425781 chr18 62943894 62943944 chr18 7184017471840224 chr18 72868729 72868779 chr10 98954242 98954292 chr10 9926527599265325 chr10 99576058 99576108 chr19 1451859 1451909 chr10 101700609101700659 chr19 5655128 5655178 chr19 8710247 8710297 chr19 1127459811274648 chr19 12438908 12438958 chr19 15334075 15334125 chr19 1797850917978559 chr19 17979127 17979177 chr19 20036101 20036151 chr19 2010893220108982 chr19 20123339 20123389 chr19 20148629 20148679 chr19 2050612420506174 chr19 21461933 21461983 chr19 21487005 21487055 chr19 2158209721582147 chr19 23147388 23147438 chr19 23911260 23911310 chr19 3931460539314655 chr19 39317296 39317346 chr19 40104065 40104115 chr19 4167218241672232 chr19 41672866 41672916 chr19 41675457 41675507 chr19 4354724643547296 chr19 43547461 43547511 chr19 43547601 43547651 chr19 4354780043547850 chr19 43548061 43548111 chr19 43981578 43981628 chr10 105032521105032571 chr19 46163266 46163316 chr19 46165258 46165308 chr19 4696455246964602 chr19 46964978 46965028 chr19 46965165 46965215 chr19 4696536346965413 chr19 47807284 47807334 chr19 47807539 47807589 chr19 4968406249684112 chr19 50840843 50840893 chr19 50841209 50841259 chr19 5084134850841398 chr19 50841695 50841745 chr10 112192597 112192647 chr1957147868 57147918 chr19 58417135 58417185 chr19 58464391 58464441 chr1958465975 58466025 chr19 58782007 58782057 chr19 59410613 59410663 chr1963609643 63609693 chr1 6075915 6075965 chr1 6485917 6485967 chr10116211014 116211064 chr1 7723387 7723437 chr1 8269871 8269921 chr18681661 8681711 chr1 9797590 9797640 chr10 6253552 6253602 chr1 2652878526528835 chr10 120686024 120686074 chr1 33476375 33476425 chr1 3486211934862169 chr10 121220529 121220579 chr1 38527309 38527359 chr1 3911456639114616 chr1 39791216 39791266 chr10 121640164 121640214 chr1 4496017144960221 chr1 45376458 45376508 chr1 48029195 48029245 chr1 4831422648314276 chr1 50217707 50217757 chr1 51548093 51548143 chr1 5270647852706528 chr10 123628332 123628382 chr1 76001630 76001680 chr1 7600200576002055 chr1 76002671 76002721 chr1 86789105 86789155 chr1 8678945086789500 chr1 89730933 89730983 chr1 96407451 96407501 chr1 9640801596408065 chr1 96408356 96408406 chr1 96700970 96701020 chr1 9844219598442245 chr1 98442407 98442457 chr1 106309087 106309137 chr1 108058362108058412 chr1 108426146 108426196 chr1 111074871 111074921 chr1111371416 111371466 chr1 112481075 112481125 chr1 114633908 114633958chr1 143416461 143416511 chr1 146561408 146561458 chr10 126780633126780683 chr1 148841397 148841447 chr1 149385870 149385920 chr1149445795 149445845 chr1 149662123 149662173 chr1 151477705 151477755chr1 158469005 158469055 chr1 158608730 158608780 chr1 167576429167576479 chr1 173265792 173265842 chr1 173606513 173606563 chr1176249568 176249618 chr1 176628698 176628748 chr1 179647472 179647522chr1 179951552 179951602 chr1 194662399 194662449 chr1 199448114199448164 chr1 199998056 199998106 chr1 206381019 206381069 chr1209552410 209552460 chr1 210008207 210008257 chr1 210383109 210383159chr1 214754763 214754813 chr1 217697475 217697525 chr1 224294417224294467 chr1 224874141 224874191 chr1 228300473 228300523 chr1229551038 229551088 chr1 229552484 229552534 chr1 234332911 234332961chr1 234873194 234873244 chr1 243473979 243474029 chr1 244141539244141589 chr1 245774636 245774686 chr20 2996265 2996315 chr20 34180433418093 chr20 13735794 13735844 chr20 17986966 17987016 chr20 1965451819654568 chr20 24600970 24601020 chr20 29422434 29422484 chr20 3145394431453994 chr20 32489817 32489867 chr20 32841002 32841052 chr20 3300255533002605 chr20 33005345 33005395 chr20 33779746 33779796 chr20 3629237436292424 chr20 36325661 36325711 chr20 36438601 36438651 chr20 3644135136441401 chr20 37694101 37694151 chr20 37694043 37694093 chr20 3777699237777042 chr20 40870445 40870495 chr20 42921658 42921708 chr20 4496038244960432 chr20 44961126 44961176 chr20 46841293 46841343 chr20 4823887648238926 chr20 57674894 57674944 chr20 60915301 60915351 chr10 134702818134702868 chr21 28857115 28857165 chr21 39448555 39448605 chr21 4606042246060472 chr10 8914307 8914357 chr22 16899855 16899905 chr22 1726308617263136 chr22 17445438 17445488 chr22 22227124 22227174 chr22 2278666722786717 chr22 23039036 23039086 chr22 23999369 23999419 chr22 2727510627275156 chr22 28364660 28364710 chr22 28580093 28580143 chr22 3334782733347877 chr22 33404992 33405042 chr22 34957881 34957931 chr22 4027121740271267 chr22 40272363 40272413 chr22 41378973 41379023 chr11 33837953383845 chrX 6987354 6987404 chrX 6989970 6990020 chrX 12344840 12344890chr11 4123633 4123683 chrX 16345668 16345718 chrX 16349210 16349260chr11 5920275 5920325 chrX 28714872 28714922 chrX 36598374 36598424 chrX40102942 40102992 chrX 40501423 40501473 chrX 41177142 41177192 chrX41175076 41175126 chrX 43947517 43947567 chrX 45302502 45302552 chrX47019969 47020019 chrX 47126800 47126850 chrX 51824554 51824604 chrX54741759 54741809 chrX 68459317 68459367 chrX 68767264 68767314 chrX69429912 69429962 chrX 72254796 72254846 chrX 72654158 72654208 chrX75367287 75367337 chrX 75944307 75944357 chrX 76278215 76278265 chrX78409296 78409346 chrX 78723449 78723499 chrX 94078171 94078221 chrX101132432 101132482 chrX 117251510 117251560 chrX 121960814 121960864chrX 124480096 124480146 chrX 129166861 129166911 chrX 132799266132799316 chrX 134789452 134789502 chrY 8489041 8489091 chrY 1399926913999319 chr2 3204573 3204623 chr2 4979181 4979231 chr2 7499488 7499538chr2 11066028 11066078 chr2 15702967 15703017 chr2 15775102 15775152chr2 15841628 15841678 chr2 25830525 25830575 chr2 25919797 25919847chr2 26569299 26569349 chr2 27738824 27738874 chr2 32955231 32955281chr2 38135630 38135680 chr11 19847158 19847208 chr2 39830910 39830960chr2 42196472 42196522 chr2 42217298 42217348 chr2 43265845 43265895chr2 43880430 43880480 chr2 44270329 44270379 chr11 20849978 20850028chr2 47636478 47636528 chr2 48815338 48815388 chr2 51031762 51031812chr2 54298864 54298914 chr2 63925042 63925092 chr2 64011757 64011807chr2 64242968 64243018 chr2 65803506 65803556 chr2 74263993 74264043chr2 75927671 75927721 chr2 95393385 95393435 chr2 105488366 105488416chr2 113949003 113949053 chr2 128203487 128203537 chr2 133188017133188067 chr2 135032003 135032053 chr2 135936087 135936137 chr2136675380 136675430 chr11 33971889 33971939 chr2 144889273 144889323chr2 144959683 144959733 chr2 152935240 152935290 chr2 153218611153218661 chr2 157351779 157351829 chr2 157511773 157511823 chr2161499322 161499372 chr2 170385154 170385204 chr2 170563960 170564010chr2 170565362 170565412 chr2 170635216 170635266 chr2 171208056171208106 chr2 172927182 172927232 chr2 172960183 172960233 chr2173604336 173604386 chr2 178913322 178913372 chr2 191499257 191499307chr2 192808333 192808383 chr2 198764906 198764956 chr2 202306974202307024 chr2 202630818 202630868 chr2 203601228 203601278 chr2203783341 203783391 chr2 204439048 204439098 chr2 207240404 207240454chr2 207425287 207425337 chr2 222958714 222958764 chr2 223965719223965769 chr2 223966940 223966990 chr2 230809338 230809388 chr2233974469 233974519 chr2 240582472 240582522 chr3 5130570 5130620 chr35300631 5300681 chr3 8457932 8457982 chr3 9575852 9575902 chr11 4688432946884379 chr3 10087134 10087184 chr11 47026052 47026102 chr3 1286542312865473 chr3 15077438 15077488 chr3 15178450 15178500 chr3 1575815415758204 chr3 16997646 16997696 chr3 20884603 20884653 chr3 2388902423889074 chr3 32182170 32182220 chr3 39229007 39229057 chr3 4130722741307277 chr3 44824130 44824180 chr3 47955138 47955188 chr3 5008242650082476 chr3 50309759 50309809 chr11 55687513 55687563 chr3 5130461251304662 chr3 51850498 51850548 chr3 58233798 58233848 chr10 1256695812567008 chr10 12569773 12569823 chr3 61378741 61378791 chr3 6161391861613968 chr3 61616094 61616144 chr11 57260710 57260760 chr3 7189840371898453 chr3 82553872 82553922 chr3 96783608 96783658 chr11 5912773859127788 chr11 59243434 59243484 chr3 101519040 101519090 chr3 104295845104295895 chr3 104571369 104571419 chr3 107115684 107115734 chr1159744942 59744992 chr3 109065331 109065381 chr3 110164908 110164958 chr3113597058 113597108 chr3 114087325 114087375 chr3 114888903 114888953chr3 118091316 118091366 chr3 119759055 119759105 chr3 121454943121454993 chr3 123242235 123242285 chr3 123821259 123821309 chr3125791162 125791212 chr11 60710165 60710215 chr3 130380868 130380918chr3 130404254 130404304 chr3 132991237 132991287 chr3 137764369137764419 chr3 138239288 138239338 chr3 144127650 144127700 chr3146521762 146521812 chr3 150420105 150420155 chr3 151861016 151861066chr3 161218343 161218393 chr3 176171693 176171743 chr3 178931306178931356 chr3 180767784 180767834 chr3 184645997 184646047 chr3186043662 186043712 chr3 187851359 187851409 chr3 187911898 187911948chr3 187924312 187924362 chr3 191512025 191512075 chr3 197597571197597621 chr4 378714 378764 chr4 535300 535350 chr4 961158 961208 chr1164244542 64244592 chr4 16146889 16146939 chr4 37566942 37566992 chr438705577 38705627 chr4 38707069 38707119 chr4 38705526 38705576 chr440040961 40041011 chr4 40047464 40047514 chr4 54017639 54017689 chr454021168 54021218 chr4 54038863 54038913 chr4 54813739 54813789 chr455108506 55108556 chr4 57476050 57476100 chr4 57954046 57954096 chr458007002 58007052 chr11 65305886 65305936 chr4 70942426 70942476 chr470944355 70944405 chr4 70942485 70942535 chr4 79364394 79364444 chr484566567 84566617 chr4 85324228 85324278 chr4 95536618 95536668 chr4114339366 114339416 chr4 119916655 119916705 chr4 148857810 148857860chr4 152714116 152714166 chr4 152754814 152754864 chr4 152755106152755156 chr4 153024266 153024316 chr4 154366316 154366366 chr1167021005 67021055 chr4 166246269 166246319 chr4 166520004 166520054 chr4171186399 171186449 chr4 175912782 175912832 chr4 176308166 176308216chr4 184658760 184658810 chr4 186858654 186858704 chr4 186858885186858935 chr4 189274453 189274503 chr5 1638927 1638977 chr5 1633073116330781 chr11 69869284 69869334 chr5 37059846 37059896 chr5 3761019237610242 chr5 39319088 39319138 chr5 39379033 39379083 chr5 4302475743024807 chr5 43134762 43134812 chr5 43567004 43567054 chr5 4362475443624804 chr5 53692253 53692303 chr5 55009303 55009353 chr5 5532801155328061 chr5 55351451 55351501 chr5 59743627 59743677 chr5 6182633461826384 chr5 62394801 62394851 chr5 65289682 65289732 chr5 6763612667636176 chr5 68376198 68376248 chr5 70906132 70906182 chr5 7093273570932785 chr11 70606443 70606493 chr5 74649079 74649129 chr5 7465220174652251 chr5 75716644 75716694 chr5 76194250 76194300 chr5 7636584576365895 chr5 77771976 77772026 chr5 79682758 79682808 chr5 8032379880323848 chr5 83692597 83692647 chr5 87994980 87995030 chr5 107972342107972392 chr5 108403271 108403321 chr5 112367724 112367774 chr5117012722 117012772 chr5 118534935 118534985 chr5 134294759 134294809chr5 138188367 138188417 chr5 138190326 138190376 chr5 138223846138223896 chr5 138468282 138468332 chr5 138637318 138637368 chr5139836744 139836794 chr11 73335602 73335652 chr11 73375081 73375131chr11 73567595 73567645 chr5 149079492 149079542 chr5 152445451152445501 chr5 152706035 152706085 chr11 74849112 74849162 chr1175316270 75316320 chr5 175660174 175660224 chr11 76371315 76371365 chr5179179616 179179666 chr5 180308543 180308593 chr6 5781917 5781967 chr615525144 15525194 chr6 15835798 15835848 chr11 78629649 78629699 chr617842796 17842846 chr6 20046727 20046777 chr6 21906600 21906650 chr622943720 22943770 chr6 27901757 27901807 chr6 27904250 27904300 chr1182569779 82569829 chr6 30007332 30007382 chr11 82755217 82755267 chr631068038 31068088 chr6 31529046 31529096 chr6 32047682 32047732 chr632425122 32425172 chr6 33075498 33075548 chr6 33846472 33846522 chr1185546999 85547049 chr6 41630683 41630733 chr6 42481945 42481995 chr1186168516 86168566 chr6 48384900 48384950 chr6 52568954 52569004 chr653218016 53218066 chr6 55822642 55822692 chr6 56735593 56735643 chr671971793 71971843 chr6 74306245 74306295 chr6 74557303 74557353 chr674620521 74620571 chr11 90485942 90485992 chr6 76148174 76148224 chr684949859 84949909 chr6 88457425 88457475 chr6 100144530 100144580 chr6106348914 106348964 chr6 108169879 108169929 chr6 108301147 108301197chr6 108320119 108320169 chr6 112415165 112415215 chr6 112895991112896041 chr11 94903240 94903290 chr6 135666863 135666913 chr6144736050 144736100 chr6 148481686 148481736 chr6 150138187 150138237chr6 151801723 151801773 chr6 154616129 154616179 chr6 155318861155318911 chr6 158640582 158640632 chr11 105725765 105725815 chr11107320113 107320163 chr7 2086044 2086094 chr7 4174729 4174779 chr76456810 6456860 chr7 6759932 6759982 chr7 16575222 16575272 chr722828634 22828684 chr7 25929316 25929366 chr7 26043031 26043081 chr728621555 28621605 chr7 35977068 35977118 chr7 47738995 47739045 chr750268181 50268231 chr7 55122036 55122086 chr7 55213641 55213691 chr755959316 55959366 chr7 62746739 62746789 chr7 63611692 63611742 chr763682520 63682570 chr7 63841399 63841449 chr7 75195014 75195064 chr775195590 75195640 chr7 76776743 76776793 chr7 87508754 87508804 chr789986298 89986348 chr7 98638080 98638130 chr7 99098634 99098684 chr799733707 99733757 chr7 110809782 110809832 chr7 111751609 111751659 chr7127771776 127771826 chr7 132084922 132084972 chr7 132277862 132277912chr7 135314001 135314051 chr7 138529099 138529149 chr7 146891648146891698 chr7 148369249 148369299 chr7 148642197 148642247 chr7149594275 149594325 chr8 9049806 9049856 chr8 9260307 9260357 chr89260370 9260420 chr8 21579310 21579360 chr11 124112011 124112061 chr833574521 33574571 chr8 34442947 34442997 chr8 34445769 34445819 chr837841030 37841080 chr8 42814240 42814290 chr8 43293109 43293159 chr843561357 43561407 chr8 57235757 57235807 chr8 58034874 58034924 chr859639792 59639842 chr8 61512102 61512152 chr8 64143646 64143696 chr866623455 66623505 chr8 67193684 67193734 chr8 68423058 68423108 chr887664553 87664603 chr8 94007310 94007360 chr8 101860209 101860259 chr8103898175 103898225 chr8 122626152 122626202 chr11 129254868 129254918chr8 124285606 124285656 chr8 125401788 125401838 chr8 129088391129088441 chr8 129088470 129088520 chr8 131891567 131891617 chr8134725470 134725520 chr8 142184759 142184809 chr9 6612209 6612259 chr916966537 16966587 chr9 19423098 19423148 chr9 29180047 29180097 chr970879296 70879346 chr9 70923881 70923931 chr9 75026755 75026805 chr975133827 75133877 chr9 83645073 83645123 chr9 84383507 84383557 chr985832215 85832265 chr9 86318262 86318312 chr9 87064208 87064258 chr990331814 90331864 chr9 90332049 90332099 chr9 90933510 90933560 chr995938036 95938086 chr9 98209195 98209245 chr9 105413194 105413244 chr9108240280 108240330 chr9 114979963 114980013 chr9 120989652 120989702chr9 123598178 123598228 chr9 123920214 123920264 chr9 128658826128658876 chr12 7242914 7242964 chr12 7635369 7635419 chr12 86680938668143 chr12 12459818 12459868 chr12 12609163 12609213 chr12 1938447919384529 chr12 28246451 28246501 chr12 32608405 32608455 chr12 4718158547181635 chr12 47524001 47524051 chr12 47596738 47596788 chr12 4796372847963778 chr12 47963802 47963852 chr12 50326226 50326276 chr12 5109080151090851 chr12 53168476 53168526 chr12 54160277 54160327 chr12 5546497855465028 chr12 55470652 55470702 chr12 56188739 56188789 chr12 7462070574620755 chr12 79205675 79205725 chr12 94132693 94132743 chr12 9480490794804957 chr12 95055588 95055638 chr12 95055532 95055582 chr12 9919218599192235 chr12 109072525 109072575 chr12 109075119 109075169 chr12109801604 109801654 chr12 110573855 110573905 chr12 118210960 118211010chr12 121632499 121632549 chr12 122937497 122937547 chr12 129835954129836004 chr10 35698339 35698389 chr13 21232371 21232421 chr13 2334469223344742 chr13 23853347 23853397 chr13 23886147 23886197 chr13 2509698725097037 chr13 25178527 25178577 chr13 28641011 28641061 chr13 2921311229213162 chr13 30373477 30373527 chr13 31087728 31087778 chr13 3565160935651659 chr13 40253388 40253438 chr13 43053772 43053822 chr13 5045128150451331 chr10 42625880 42625930 chr13 79474134 79474184 chr13 8632792086327970 chr13 94042622 94042672 chr13 97593377 97593427 chr13 106132342106132392 chr13 108957655 108957705 chr13 112443952 112444002 chr1045111597 45111647 chr14 18670218 18670268 chr14 18963225 18963275 chr1045290795 45290845 chr14 29897533 29897583 chr14 32539370 32539420 chr1434285635 34285685 chr14 34285988 34286038 chr14 34437910 34437960 chr1436015784 36015834 chr14 40131951 40132001 chr14 40134862 40134912 chr1440135220 40135270 chr14 53913324 53913374 chr14 57514566 57514616 chr1461621604 61621654 chr14 62495720 62495770 chr14 65002647 65002697 chr1470693616 70693666 chr14 71642570 71642620 chr10 52497811 52497861 chr1052497995 52498045 chr14 74382855 74382905 chr14 75189882 75189932 chr1475277927 75277977 chr14 76450964 76451014 chr14 78741830 78741880 chr1481271688 81271738 chr14 83809998 83810048 chr14 84287070 84287120 chr1490014834 90014884 chr14 100629249 100629299 chr14 101134995 101135045chr14 103518394 103518444 chr15 24812598 24812648 chr15 3295459432954644 chr15 41176502 41176552 chr15 43302398 43302448 chr15 4755952347559573 chr10 64915612 64915662 chr10 64916068 64916118 chr10 6491686164916911 chr10 64917206 64917256 chr15 60341617 60341667 chr15 6069930660699356 chr15 66141657 66141707 chr15 66145040 66145090 chr15 6686676366866813 chr15 66869293 66869343 chr15 66973811 66973861 chr10 6879438468794434 chr10 68795183 68795233 chr15 70816629 70816679 chr15 7273807972738129 chr15 82211845 82211895 chr15 82945019 82945069 chr15 8756883987568889 chr15 88250004 88250054 chr15 90880648 90880698 chr15 9104246991042519 chr15 99050468 99050518 chr16 2210094 2210144 chr16 22111732211223 chr16 2390927 2390977 chr16 3321835 3321885 chr16 79524627952512 chr16 8795301 8795351 chr16 11396349 11396399 chr10 7151290271512952 chr10 71513053 71513103 chr16 14593842 14593892 chr10 7173479671734846 chr16 31150915 31150965 chr16 31279128 31279178 chr16 3141548031415530 chr16 31883300 31883350 chr16 46469163 46469213 chr16 4681428746814337 chr16 48762926 48762976 chr16 49023177 49023227 chr10 7297538372975433 chr10 72975897 72975947 chr10 72976020 72976070 chr10 7298115872981208 chr10 72981303 72981353 chr16 53350948 53350998 chr16 5351093053510980 chr16 57011286 57011336 chr16 58207131 58207181 chr16 5865637258656422 chr16 67974562 67974612 chr16 69091625 69091675 chr16 6985965469859704 chr16 71398847 71398897 chr16 80058285 80058335 chr16 8927291989272969 chr17 1800608 1800658 chr17 2616089 2616139 chr17 32216533221703 chr17 3482778 3482828 chr17 5246313 5246363 chr17 58258755825925 chr17 8655083 8655133 chr17 16084032 16084082 chr17 1619806616198116 chr17 17547553 17547603 chr17 18017576 18017626 chr10 7957410979574159 chr10 79574395 79574445 chr17 27077855 27077905 chr17 2800519828005248 chr17 28996952 28997002 chr17 28995257 28995307 chr17 2920912029209170 chr17 37161394 37161444 chr17 37462476 37462526 Table 15EC.Repeat Category K.standard.SVA_E chr17 76370870 76370920 chr10 9836680198366851 chr19 21694870 21694920 chr19 23108961 23109011 chr19 5800490258004952 chr19 58115312 58115362 chr19 58384220 58384270 chr1 77239857724035 chr1 24509715 24509765 chr1 24512635 24512685 chr1 2699478326994833 chr1 32940987 32941037 chr1 32941385 32941435 chr1 3294201932942069 chr1 32944060 32944110 chr1 42629117 42629167 chr1 4510291745102967 chr1 48220000 48220050 chr1 77759401 77759451 chr1 148790802148790852 chr1 153745730 153745780 chr1 209527408 209527458 chr1231488680 231488730 chr20 2798081 2798131 chr20 4007499 4007549 chr2053551561 53551611 chr21 43092298 43092348 chr22 29746663 29746713 chr2229748744 29748794 chrX 52766633 52766683 chrX 66412501 66412551 chrX66415982 66416032 chrX 70266731 70266781 chr11 8963146 8963196 chrX90848034 90848084 chr2 117882 117932 chr2 15382130 15382180 chr227756436 27756486 chr2 32648272 32648322 chr2 44791739 44791789 chr2129270462 129270512 chr2 133191550 133191600 chr2 192466848 192466898chr2 201752061 201752111 chr2 202349139 202349189 chr2 215903950215904000 chr2 217295015 217295065 chr3 38085537 38085587 chr3 131906916131906966 chr3 182965395 182965445 chr4 106490235 106490285 chr4185354845 185354895 chr5 40845960 40846010 chr5 137098703 137098753 chr64982114 4982164 chr6 21960749 21960799 chr6 51892806 51892856 chr656804762 56804812 chr6 131446015 131446065 chr6 131445396 131445446 chr72319330 2319380 chr7 20451686 20451736 chr7 32169759 32169809 chr7151676285 151676335 chr8 30163171 30163221 chr8 43053908 43053958 chr849111125 49111175 chr8 99998632 99998682 chr8 117649872 117649922 chr8128598924 128598974 chr11 130492741 130492791 chr9 132101873 132101923chr9 132102501 132102551 chr9 132103362 132103412 chr9 132104232132104282 chr12 8496022 8496072 chr12 8671060 8671110 chr12 93929039392953 chr12 68881105 68881155 chr12 88764115 88764165 chr12 9473876794738817 chr10 32264631 32264681 chr10 43202584 43202634 chr14 2109815221098202 chr14 63350373 63350423 chr14 63353560 63353610 chr10 6405350064053550 chr10 2803222 2803272 chr10 71098249 71098299 chr10 7109847671098526 chr16 31153208 31153258 chr16 69861995 69862045 chr16 7230683272306882 chr17 25683858 25683908 chr17 29453937 29453987 chr17 3139373431393784 chr17 31396394 31396444 Table 15ED. Repeat CategoryK.standard.SVA_F chr17 42734324 42734374 chr17 59104693 59104743 chr1779274921 79274971 chr17 79277553 79277603 chr18 45357576 45357626 chr1845577496 45577546 chr18 50122968 50123018 chr10 101516416 101516466chr10 101519286 101519336 chr19 12594362 12594412 chr19 1367446313674513 chr19 21841739 21841789 chr19 22083508 22083558 chr19 3926107439261124 chr19 39263427 39263477 chr10 104552012 104552062 chr1945307583 45307633 chr19 45307871 45307921 chr10 106209953 106210003chr10 6101851 6101901 chr1 20820932 20820982 chr1 24478767 24478817 chr126750546 26750596 chr1 27786309 27786359 chr10 121147198 121147248 chr154068147 54068197 chr1 54396246 54396296 chr1 108564251 108564301 chr1111450444 111450494 chr1 111641250 111641300 chr1 112616833 112616883chr1 112740854 112740904 chr1 112913061 112913111 chr1 117317734117317784 chr1 117320217 117320267 chr1 147916626 147916676 chr1147918894 147918944 chr1 152887053 152887103 chr1 171556599 171556649chr1 212100487 212100537 chr1 238620763 238620813 chr20 1620429316204343 chr20 31510455 31510505 chr20 34455925 34455975 chr21 1758757117587621 chr21 45543355 45543405 chr22 25494761 25494811 chr22 3031621530316265 chrX 24089807 24089857 chrX 41365260 41365310 chrX 5182364651823696 chrX 61277107 61277157 chrX 70769609 70769659 chrX 7430638374306433 chrX 99000336 99000386 chrX 113347469 113347519 chrX 145741311145741361 chrX 152469870 152469920 chr11 17037506 17037556 chr2 4194766141947711 chr2 41950404 41950454 chr2 42808785 42808835 chr2 4349827143498321 chr2 43500315 43500365 chr2 48756212 48756262 chr2 4876007948760129 chr2 55976416 55976466 chr2 64713834 64713884 chr11 2841505128415101 chr2 96957427 96957477 chr2 108965316 108965366 chr2 120698151120698201 chr2 127971499 127971549 chr2 187222385 187222435 chr2198989211 198989261 chr2 198991529 198991579 chr2 207467114 207467164chr2 223884739 223884789 chr11 44650882 44650932 chr2 234920756234920806 chr11 45725549 45725599 chr3 10433363 10433413 chr11 4708284447082894 chr3 11504319 11504369 chr3 17722705 17722755 chr3 4279892842798978 chr3 51244702 51244752 chr3 57689952 57690002 chr3 5883451958834569 chr3 67426687 67426737 chr3 77134394 77134444 chr3 9987913799879187 chr3 102478471 102478521 chr3 107151613 107151663 chr3123203406 123203456 chr3 123206645 123206695 chr3 125409128 125409178chr3 129992950 129993000 chr3 133511983 133512033 chr3 134823890134823940 chr3 180330420 180330470 chr4 1790346 1790396 chr4 4828244948282499 chr4 53244584 53244634 chr4 64787918 64787968 chr4 147192912147192962 chr4 152159877 152159927 chr4 159135764 159135814 chr4159136799 159136849 chr4 161439611 161439661 chr4 182562933 182562983chr5 34353384 34353434 chr5 77174987 77175037 chr5 81518850 81518900chr5 81521351 81521401 chr5 108755363 108755413 chr11 71940955 71941005chr5 141485397 141485447 chr5 167266580 167266630 chr5 168052697168052747 chr5 170555625 170555675 chr5 170812871 170812921 chr5175711689 175711739 chr5 176368109 176368159 chr5 176368289 176368339chr5 178060017 178060067 chr11 76534761 76534811 chr11 76537673 76537723chr6 15296543 15296593 chr6 27562392 27562442 chr6 31925025 31925075chr6 32668245 32668295 chr6 34411459 34411509 chr6 35354218 35354268chr6 35355721 35355771 chr6 35356410 35356460 chr6 35357115 35357165chr6 38979060 38979110 chr6 43596909 43596959 chr6 47521404 47521454chr6 87716483 87716533 chr11 93369556 93369606 chr6 109412841 109412891chr6 109414914 109414964 chr6 112875966 112876016 chr11 9474367594743725 chr6 123152233 123152283 chr6 158458359 158458409 chr6162668401 162668451 chr7 820041 820091 chr7 820866 820916 chr7 20535222053572 chr7 10250728 10250778 chr7 24799709 24799759 chr7 2974289629742946 chr7 51018528 51018578 chr7 55030827 55030877 chr7 9995189399951943 chr11 118917246 118917296 chr10 17676024 17676074 chr8 9080290852 chr8 5569478 5569528 chr8 62716767 62716817 chr8 65647631 65647681chr8 68274453 68274503 chr8 124283125 124283175 chr8 128287078 128287128chr8 129796003 129796053 chr11 129500602 129500652 chr9 6796826 6796876chr9 36606303 36606353 chr9 70914608 70914658 chr9 74135004 74135054chr9 94849984 94850034 chr9 94850112 94850162 chr9 94850295 94850345chr9 105400664 105400714 chr9 105920431 105920481 chr9 110658031110658081 chr9 118635803 118635853 chr9 121196388 121196438 chr9123467552 123467602 chr12 3075706 3075756 chr10 21723109 21723159 chr129995855 9995905 chr12 9995804 9995854 chr12 36496322 36496372 chr1254756803 54756853 chr10 27590438 27590488 chr12 64813502 64813552 chr1297551979 97552029 chr12 103218909 103218959 chr12 109715997 109716047chr12 112721510 112721560 chr12 118769879 118769929 chr12 120828334120828384 chr13 18150467 18150517 chr13 19819222 19819272 chr13 3291178232911832 chr13 32913879 32913929 chr13 41337783 41337833 chr13 4385894343858993 chr13 44887929 44887979 chr13 71948442 71948492 chr14 3349772833497778 chr14 43848168 43848218 chr14 43850302 43850352 chr14 9136926991369319 chr15 33663776 33663826 chr15 37903549 37903599 chr15 3939251139392561 chr15 73488837 73488887 chr15 88126493 88126543 chr15 8813994588139995 chr15 88142660 88142710 chr16 1588642 1588692 chr16 28531592853209 chr10 71793315 71793365 chr10 71793421 71793471 chr16 3021683630216886 chr16 46509889 46509939 chr16 56550325 56550375 chr10 7643859476438644 chr10 76438918 76438968 chr17 15742449 15742499 chr17 1899270518992755 chr17 18993007 18993057 chr17 19694535 19694585 chr17 2692926926929319 chr17 36120972 36121022 Table 15EE. Repeat Category THE1B chr1742046940 42046990 chr17 44573850 44573900 chr17 47210829 47210879 chr1753924503 53924553 chr17 55593418 55593468 chr17 56249321 56249371 chr1758985856 58985906 chr17 64629756 64629806 chr17 67420693 67420743 chr1768156863 68156913 chr17 68806705 68806755 chr17 69052188 69052238 chr1771090845 71090895 chr17 71176123 71176173 chr17 71743866 71743916 chr1773016291 73016341 chr17 75446350 75446400 chr10 90222619 90222669 chr1777252911 77252961 chr17 77260496 77260546 chr17 78442231 78442281 chr1779323136 79323186 chr17 80036141 80036191 chr17 81671328 81671378 chr18829547 829597 chr18 829394 829444 chr10 94044869 94044919 chr18 1068901110689061 chr18 19271431 19271481 chr18 25556777 25556827 chr18 4072347640723526 chr18 49340626 49340676 chr18 49900860 49900910 chr18 5446913654469186 chr18 54911314 54911364 chr18 60314204 60314254 chr18 6207481962074869 chr18 62682608 62682658 chr18 67038604 67038654 chr18 7383285773832907 chr18 74185717 74185767 chr18 74185622 74185672 chr19 12991451299195 chr19 1646460 1646510 chr19 2779151 2779201 chr19 74271277427177 chr19 8073567 8073617 chr19 9135767 9135817 chr19 1689913416899184 chr19 17475311 17475361 chr19 36311614 36311664 chr19 3850568238505732 chr10 104557250 104557300 chr19 44231592 44231642 chr10108428542 108428592 chr19 50804617 50804667 chr19 51435136 51435186chr19 51518505 51518555 chr19 51721882 51721932 chr19 51734352 51734402chr19 51755106 51755156 chr19 51839634 51839684 chr19 53313249 53313299chr19 57583805 57583855 chr10 113623780 113623830 chr19 5923181359231863 chr19 59596809 59596859 chr19 63435711 63435761 chr1 32124133212463 chr1 4195857 4195907 chr1 4844173 4844223 chr1 4981898 4981948chr1 5022830 5022880 chr1 5588551 5588601 chr1 7678680 7678730 chr18106904 8106954 chr1 8370136 8370186 chr1 11177088 11177138 chr117252240 17252290 chr1 17907531 17907581 chr1 19588040 19588090 chr120414039 20414089 chr1 28819162 28819212 chr1 36402273 36402323 chr138234531 38234581 chr1 40385179 40385229 chr1 42629117 42629167 chr149103716 49103766 chr1 49527992 49528042 chr1 53182699 53182749 chr153596568 53596618 chr1 53840269 53840319 chr1 56325651 56325701 chr161496107 61496157 chr1 68799890 68799940 chr1 69175825 69175875 chr171234370 71234420 chr1 71585873 71585923 chr1 74840872 74840922 chr179814000 79814050 chr1 85357258 85357308 chr1 85357318 85357368 chr189423581 89423631 chr1 99533644 99533694 chr1 109517637 109517687 chr1111516843 111516893 chr1 155559572 155559622 chr1 171969996 171970046chr10 7408920 7408970 chr1 178238244 178238294 chr1 179537310 179537360chr1 186732464 186732514 chr1 195337604 195337654 chr10 130344607130344657 chr1 208013082 208013132 chr1 212821477 212821527 chr1213813940 213813990 chr1 217588493 217588543 chr1 220594274 220594324chr1 229472518 229472568 chr1 229963425 229963475 chr10 131398337131398387 chr1 241996481 241996531 chr20 802400 802450 chr20 33713283371378 chr10 132740818 132740868 chr20 6977179 6977229 chr20 1197881811978868 chr20 12426160 12426210 chr20 18719841 18719891 chr20 1916495319165003 chr20 21719523 21719573 chr20 30715808 30715858 chr10 133573984133574034 chr20 37795091 37795141 chr20 40705751 40705801 chr20 4193525641935306 chr20 43356433 43356483 chr10 133920653 133920703 chr2046033549 46033599 chr20 46033343 46033393 chr20 54455748 54455798 chr2060878152 60878202 chr21 16377594 16377644 chr21 21121219 21121269 chr2125684095 25684145 chr21 26666236 26666286 chr21 29574112 29574162 chr2130165196 30165246 chr21 33290009 33290059 chr21 39306627 39306677 chr2139710579 39710629 chr21 40782219 40782269 chr21 41353072 41353122 chr2142030147 42030197 chr21 43841239 43841289 chr21 43940646 43940696 chr2144854458 44854508 chr21 46317397 46317447 chr21 46432727 46432777 chr2146433136 46433186 chr22 26992125 26992175 chr22 31383600 31383650 chr2235585170 35585220 chr22 41712815 41712865 chr22 43171879 43171929 chr2245665754 45665804 chr22 45708952 45709002 chr22 45748610 45748660 chr2246101425 46101475 chr22 46803563 46803613 chr22 47803519 47803569 chr2248057909 48057959 chrX 17465100 17465150 chrX 20086619 20086669 chrX22554826 22554876 chrX 22612177 22612227 chrX 23832987 23833037 chr117062758 7062808 chrX 46301998 46302048 chrX 47554064 47554114 chr118178181 8178231 chrX 71991359 71991409 chrX 91981633 91981683 chrX112060891 112060941 chrX 122281490 122281540 chrX 130001775 130001825chrX 130206232 130206282 chrX 143765113 143765163 chrX 150348778150348828 chrY 6476963 6477013 chr11 14279320 14279370 chrY 71256857125735 chrY 20330654 20330704 chrY 22684288 22684338 chr2 306520 306570chr2 1885133 1885183 chr2 1967072 1967122 chr10 11438947 11438997 chr23791064 3791114 chr2 4728337 4728387 chr2 7131952 7132002 chr2 93594189359468 chr2 9867616 9867666 chr2 10139813 10139863 chr2 1618797816188028 chr2 17990089 17990139 chr2 21237468 21237518 chr2 2474541124745461 chr2 38102124 38102174 chr2 44367925 44367975 chr2 4760802547608075 chr2 52650394 52650444 chr2 61479885 61479935 chr2 6552006265520112 chr2 68889480 68889530 chr11 25615137 25615187 chr2 7139964671399696 chr2 83562275 83562325 chr2 87419465 87419515 chr2 9954153599541585 chr2 99541479 99541529 chr2 100220279 100220329 chr2 102305463102305513 chr2 110650530 110650580 chr11 32214292 32214342 chr2112600698 112600748 chr2 113302667 113302717 chr2 114666213 114666263chr2 117696100 117696150 chr2 118876651 118876701 chr2 119017236119017286 chr11 32593362 32593412 chr2 128676950 128677000 chr2132034989 132035039 chr2 132082474 132082524 chr2 139205273 139205323chr2 140775550 140775600 chr2 144889273 144889323 chr2 153798978153799028 chr2 154886295 154886345 chr11 34861570 34861620 chr2165651095 165651145 chr2 167201731 167201781 chr2 174487761 174487811chr11 37203237 37203287 chr11 37943405 37943455 chr2 185398017 185398067chr2 186474851 186474901 chr2 186977083 186977133 chr2 188363292188363342 chr2 191940414 191940464 chr11 40004103 40004153 chr2209605296 209605346 chr2 216896350 216896400 chr2 216896575 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142618147142618197 chr5 142886871 142886921 chr11 73894768 73894818 chr5150904173 150904223 chr5 150977147 150977197 chr5 158705564 158705614chr5 164509259 164509309 chr5 164851956 164852006 chr5 170497918170497968 chr5 172429660 172429710 chr6 7894607 7894657 chr6 1118062211180672 chr6 11750023 11750073 chr6 18631144 18631194 chr6 2127838821278438 chr6 23166551 23166601 chr6 32733241 32733291 chr6 3385882833858878 chr6 39158373 39158423 chr6 47459498 47459548 chr11 8830443688304486 chr6 69561804 69561854 chr6 76241121 76241171 chr6 7930345979303509 chr6 81764187 81764237 chr6 81883614 81883664 chr11 9239639892396448 chr6 97823329 97823379 chr6 110586960 110587010 chr6 113033877113033927 chr6 120363234 120363284 chr6 128004232 128004282 chr6129277061 129277111 chr6 131778119 131778169 chr6 134437302 134437352chr6 136892550 136892600 chr6 140204144 140204194 chr6 140474705140474755 chr6 140822079 140822129 chr6 146093820 146093870 chr6146092174 146092224 chr6 149156857 149156907 chr6 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108389817 108389867 chr7 115782481 115782531chr7 116635908 116635958 chr7 120878667 120878717 chr7 121472273121472323 chr7 131845710 131845760 chr11 118415010 118415060 chr7134203050 134203100 chr7 135107266 135107316 chr10 17516850 17516900chr7 137477211 137477261 chr7 148435669 148435719 chr7 153021703153021753 chr7 154451895 154451945 chr7 156268675 156268725 chr7156268457 156268507 chr7 158163649 158163699 chr8 196756 196806 chr11120910436 120910486 chr8 3497098 3497148 chr8 10420439 10420489 chr812658175 12658225 chr8 14644106 14644156 chr8 15394187 15394237 chr816903837 16903887 chr8 21224902 21224952 chr11 122849124 122849174 chr824115056 24115106 chr11 123072192 123072242 chr8 27809634 27809684 chr830133875 30133925 chr8 30174141 30174191 chr8 30874375 30874425 chr831166658 31166708 chr8 33574521 33574571 chr8 37495402 37495452 chr856652156 56652206 chr8 57531322 57531372 chr8 58881323 58881373 chr864498787 64498837 chr8 85484953 85485003 chr8 87539909 87539959 chr11126704776 126704826 chr8 91586500 91586550 chr8 111345140 111345190 chr8112393415 112393465 chr8 116270696 116270746 chr8 116838334 116838384chr8 122474439 122474489 chr8 124680721 124680771 chr8 127792715127792765 chr8 131439329 131439379 chr8 132576368 132576418 chr8135686406 135686456 chr8 137559036 137559086 chr8 139797068 139797118chr8 139905464 139905514 chr8 140835125 140835175 chr11 130326971130327021 chr9 7351896 7351946 chr11 132134187 132134237 chr9 1016188710161937 chr9 16596905 16596955 chr9 16907364 16907414 chr9 1778867517788725 chr9 20086102 20086152 chr9 21908394 21908444 chr9 2471475724714807 chr9 26623809 26623859 chr9 30022898 30022948 chr9 3156860731568657 chr9 31714485 31714535 chr9 38252030 38252080 chr9 3923789839237948 chr9 41213594 41213644 chr9 63665818 63665868 chr9 8095153880951588 chr11 133851619 133851669 chr9 87832548 87832598 chr9 8791161087911660 chr9 91250072 91250122 chr9 99921541 99921591 chr9 106507549106507599 chr9 107736555 107736605 chr9 113485125 113485175 chr9118660347 118660397 chr9 122248827 122248877 chr9 123920214 123920264chr9 128713706 128713756 chr9 130240519 130240569 chr9 133203778133203828 chr9 133763238 133763288 chr9 134187415 134187465 chr101066339 1066389 chr12 9739054 9739104 chr12 16683725 16683775 chr1217198287 17198337 chr12 19022674 19022724 chr12 25000045 25000095 chr1233662885 33662935 chr12 33892301 33892351 chr12 39767360 39767410 chr1241983462 41983512 chr10 25343511 25343561 chr12 53957670 53957720 chr1261191808 61191858 chr12 62231614 62231664 chr10 27987185 27987235 chr1262426679 62426729 chr12 64700655 64700705 chr12 68985178 68985228 chr1269544663 69544713 chr10 28759765 28759815 chr12 69738770 69738820 chr1275764879 75764929 chr12 76763515 76763565 chr12 81471420 81471470 chr1286677801 86677851 chr10 29437955 29438005 chr12 89632706 89632756 chr1295024436 95024486 chr12 103250232 103250282 chr12 104194657 104194707chr12 104649411 104649461 chr10 30355749 30355799 chr10 3057188930571939 chr12 113456838 113456888 chr12 114795515 114795565 chr12116404850 116404900 chr12 119185258 119185308 chr12 123612332 123612382chr12 125406029 125406079 chr12 125700319 125700369 chr12 130579787130579837 chr13 24833257 24833307 chr13 30255140 30255190 chr13 3909354239093592 chr13 44799080 44799130 chr13 51199299 51199349 chr13 5720879557208845 chr13 57341338 57341388 chr13 66480332 66480382 chr13 7142362171423671 chr13 72445465 72445515 chr13 72614089 72614139 chr13 7629798376298033 chr13 83285692 83285742 chr13 86870219 86870269 chr13 9046948090469530 chr13 93624225 93624275 chr13 96419543 96419593 chr13 9647946896479518 chr13 97470666 97470716 chr13 102174450 102174500 chr13103680574 103680624 chr13 108611014 108611064 chr13 112540959 112541009chr13 112663109 112663159 chr14 25625906 25625956 chr14 2699819026998240 chr14 27061331 27061381 chr14 28819290 28819340 chr14 3145666931456719 chr14 33186802 33186852 chr14 33650029 33650079 chr14 3566330935663359 chr14 50851666 50851716 chr14 55861576 55861626 chr14 6238398962384039 chr14 62992791 62992841 chr14 62992590 62992640 chr14 6299253762992587 chr14 65077682 65077732 chr14 68287292 68287342 chr14 6877050468770554 chr14 76813719 76813769 chr14 87837040 87837090 chr14 8783692787836977 chr14 88609259 88609309 chr14 89882172 89882222 chr14 9132954491329594 chr14 95725985 95726035 chr10 56682870 56682920 chr14 9775157197751621 chr14 99507267 99507317 chr14 100565595 100565645 chr14103461211 103461261 chr14 103742588 103742638 chr14 105044041 105044091chr15 21626928 21626978 chr15 33747774 33747824 chr15 38023953 38024003chr15 38022802 38022852 chr10 2470547 2470597 chr15 46266739 46266789chr15 48903231 48903281 chr15 54405149 54405199 chr15 54404697 54404747chr15 55036113 55036163 chr15 69202348 69202398 chr15 70253685 70253735chr15 74973933 74973983 chr15 79987446 79987496 chr15 88229107 88229157chr15 90630924 90630974 chr15 92440803 92440853 chr15 93382980 93383030chr15 96711319 96711369 chr15 98052588 98052638 chr16 1786565 1786615chr10 3031800 3031850 chr16 6234799 6234849 chr16 8635088 8635138 chr1610607829 10607879 chr16 12523437 12523487 chr16 12879834 12879884 chr1613111964 13112014 chr16 13549629 13549679 chr16 16938176 16938226 chr1618273340 18273390 chr16 18921356 18921406 chr16 23682763 23682813 chr1625318826 25318876 chr16 36142653 36142703 chr16 47955794 47955844 chr1647955886 47955936 chr16 50286274 50286324 chr16 54070311 54070361 chr1659893668 59893718 chr16 59895581 59895631 chr16 64726423 64726473 chr1665514498 65514548 chr16 65564315 65564365 chr10 73524388 73524438 chr1073524915 73524965 chr16 71040536 71040586 chr16 77644386 77644436 chr1677756101 77756151 chr16 83089844 83089894 chr16 83828862 83828912 chr1683829759 83829809 chr16 86525439 86525489 chr16 88154523 88154573 chr1689471616 89471666 chr17 166183 166233 chr10 76934632 76934682 chr1710334296 10334346 chr17 10395358 10395408 chr17 11859589 11859639 chr1714134391 14134441 Table 15EF. Repeat Category THE1B-int chr17 5898585658985906 chr17 68806705 68806755 chr10 90222619 90222669 chr18 2555677725556827 chr1 69175825 69175875 chr1 89423581 89423631 chr20 1242616012426210 chr21 43841239 43841289 chrX 91981633 91981683 chrY 2033065420330704 chrY 22684288 22684338 chr2 44367925 44367975 chr2 4760802547608075 chr2 119017236 119017286 chr2 132082474 132082524 chr2153798978 153799028 chr11 37203237 37203287 chr2 226604718 226604768chr11 49732024 49732074 chr3 58836981 58837031 chr11 58306356 58306406chr4 36905067 36905117 chr4 162765339 162765389 chr5 34340955 34341005chr5 35676444 35676494 chr5 82493950 82494000 chr5 130538202 130538252chr11 88304436 88304486 chr6 69561804 69561854 chr6 97823329 97823379chr8 16903837 16903887 chr11 123072192 123072242 chr8 85484953 85485003chr8 111345140 111345190 chr8 112393415 112393465 chr9 30022898 30022948chr12 33662885 33662935 chr12 119185258 119185308 chr13 7629798376298033 chr13 86870219 86870269 chr14 105044041 105044091 chr1538022802 38022852 chr15 46266739 46266789 chr15 48903231 48903281 chr1554405149 54405199 chr16 59895581 59895631 Table 15EG. Repeat CategoryTHE1C chr17 47636949 47636999 chr17 59796751 59796801 chr17 7093768870937738 chr17 71770126 71770176 chr17 71769983 71770033 chr17 7570443475704484 chr17 77242580 77242630 chr17 80241373 80241423 chr17 8167132881671378 chr18 3467435 3467485 chr18 10880787 10880837 chr18 1088055310880603 chr18 27651163 27651213 chr18 34123316 34123366 chr18 4396638343966433 chr18 46022379 46022429 chr18 53362630 53362680 chr18 5927584159275891 chr18 65006100 65006150 chr18 69004879 69004929 chr19 14987421498792 chr19 5858131 5858181 chr19 14674487 14674537 chr19 1550269615502746 chr10 103154131 103154181 chr19 16611216 16611266 chr1916739076 16739126 chr19 19158816 19158866 chr19 19158653 19158703 chr1938965314 38965364 chr19 40384870 40384920 chr10 105726634 105726684chr10 105726430 105726480 chr19 49277897 49277947 chr19 4927732349277373 chr19 49277174 49277224 chr19 56968063 56968113 chr10 113271742113271792 chr19 62513169 62513219 chr1 1111178 1111228 chr10 115253082115253132 chr1 4849482 4849532 chr1 4884680 4884730 chr1 8626060 8626110chr10 117868280 117868330 chr1 11349731 11349781 chr1 13370416 13370466chr1 14410031 14410081 chr1 14925969 14926019 chr1 17190858 17190908chr1 22161436 22161486 chr1 22161959 22162009 chr1 24139471 24139521chr1 26865623 26865673 chr1 42883165 42883215 chr1 51972234 51972284chr1 52401142 52401192 chr1 68504022 68504072 chr1 71111524 71111574chr1 82304581 82304631 chr1 90539795 90539845 chr1 90576122 90576172chr1 94974324 94974374 chr1 99880378 99880428 chr1 102879865 102879915chr1 103466771 103466821 chr1 103466554 103466604 chr1 105493440105493490 chr1 172743711 172743761 chr10 7379746 7379796 chr1 184823767184823817 chr1 189009555 189009605 chr1 190218654 190218704 chr10129903512 129903562 chr1 215737520 215737570 chr1 221098520 221098570chr1 236612610 236612660 chr1 237841373 237841423 chr20 2604173 2604223chr20 6998114 6998164 chr20 21044779 21044829 chr20 36989239 36989289chr20 36989301 36989351 chr20 45998497 45998547 chr10 134321538134321588 chr20 62054459 62054509 chr21 14578330 14578380 chr21 1801177718011827 chr21 18440570 18440620 chr21 19085399 19085449 chr21 1993659519936645 chr11 328409 328459 chr21 27277749 27277799 chr21 3322979733229847 chr21 34161574 34161624 chr21 36079690 36079740 chr21 4401563544015685 chr22 26678574 26678624 chr22 29507642 29507692 chr22 3024687430246924 chr22 30937629 30937679 chr22 32139915 32139965 chr11 23141292314179 chr22 39414817 39414867 chr22 42886770 42886820 chr22 4766481147664861 chrX 18675482 18675532 chrX 23345481 23345531 chrX 3431419434314244 chrX 69653256 69653306 chrX 94984346 94984396 chrX 103537075103537125 chrX 117705092 117705142 chrX 123955784 123955834 chrX126289963 126290013 chrX 147505293 147505343 chr2 2377763 2377813 chr29840685 9840735 chr2 13234301 13234351 chr2 15467661 15467711 chr216957702 16957752 chr2 16963579 16963629 chr2 25084839 25084889 chr230636170 30636220 chr2 33143789 33143839 chr2 43556443 43556493 chr245792265 45792315 chr2 48443015 48443065 chr2 72100823 72100873 chr275983835 75983885 chr2 76517586 76517636 chr2 76627852 76627902 chr1128931923 28931973 chr2 98155727 98155777 chr2 101450677 101450727 chr2120551745 120551795 chr2 138298836 138298886 chr2 138300527 138300577chr2 153447456 153447506 chr2 157485698 157485748 chr2 162189849162189899 chr2 166651450 166651500 chr2 173446723 173446773 chr2185068466 185068516 chr2 193555207 193555257 chr11 39435511 39435561chr2 222866721 222866771 chr2 228366029 228366079 chr2 238274355238274405 chr2 242108191 242108241 chr3 2121831 2121881 chr3 35238363523886 chr3 15963889 15963939 chr3 25726329 25726379 chr3 2655940826559458 chr3 34358519 34358569 chr3 35394429 35394479 chr3 3539418035394230 chr3 65494761 65494811 chr3 78636160 78636210 chr3 8050401580504065 chr3 80540590 80540640 chr3 89938698 89938748 chr3 9647030596470355 chr3 151746498 151746548 chr3 169182658 169182708 chr3189820271 189820321 chr3 190419862 190419912 chr3 192017425 192017475chr3 197913520 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chr5119822132 119822182 chr5 131102301 131102351 chr5 154221110 154221160chr5 171682541 171682591 chr5 175033526 175033576 chr11 7927779179277841 chr6 19396981 19397031 chr6 22335432 22335482 chr11 8209582382095873 chr6 38350720 38350770 chr6 78914374 78914424 chr6 8286586482865914 chr11 92234017 92234067 chr6 88276143 88276193 chr6 124062745124062795 chr6 131069295 131069345 chr6 135018284 135018334 chr6147372997 147373047 chr6 162514826 162514876 chr6 164857617 164857667chr6 166580567 166580617 chr6 168234169 168234219 chr6 169002116169002166 chr7 1382434 1382484 chr7 6418626 6418676 chr7 1257799812578048 chr7 26420224 26420274 chr7 26420115 26420165 chr7 3429511534295165 chr10 16844169 16844219 chr7 70156268 70156318 chr7 7041135070411400 chr7 70458206 70458256 chr7 77059161 77059211 chr7 8022937580229425 chr7 81250549 81250599 chr7 81250418 81250468 chr7 103231387103231437 chr7 109874535 109874585 chr7 109873879 109873929 chr7114335151 114335201 chr7 152865004 152865054 chr7 153186761 153186811chr7 156992896 156992946 chr8 20892229 20892279 chr8 23390529 23390579chr8 32692131 32692181 chr8 36060383 36060433 chr8 37969979 37970029chr8 90454413 90454463 chr8 92391559 92391609 chr8 93846504 93846554chr8 99641042 99641092 chr8 99640925 99640975 chr8 102319454 102319504chr8 113724457 113724507 chr10 19046603 19046653 chr8 120260590120260640 chr8 120511484 120511534 chr8 121028932 121028982 chr8122755841 122755891 chr8 137041338 137041388 chr8 138102901 138102951chr9 17112347 17112397 chr9 23250170 23250220 chr9 30232420 30232470chr9 32372950 32373000 chr9 80494479 80494529 chr9 82177141 82177191chr9 134021015 134021065 chr12 22312918 22312968 chr12 44691388 44691438chr12 50562628 50562678 chr12 54329295 54329345 chr12 55464978 55465028chr12 56891407 56891457 chr12 58293089 58293139 chr12 58292495 58292545chr12 68651706 68651756 chr12 101347960 101348010 chr12 103309216103309266 chr12 103309123 103309173 chr12 111867216 111867266 chr12121083009 121083059 chr12 126398245 126398295 chr13 28786641 28786691chr13 51556435 51556485 chr13 54879434 54879484 chr13 85212997 85213047chr13 86267888 86267938 chr13 97545414 97545464 chr13 99421029 99421079chr13 109534311 109534361 chr14 43660329 43660379 chr14 4530387045303920 chr14 45673413 45673463 chr14 54971915 54971965 chr14 6376487163764921 chr14 65189705 65189755 chr14 67742249 67742299 chr14 6920454869204598 chr14 71843915 71843965 chr14 75633597 75633647 chr14 7940138379401433 chr14 87921362 87921412 chr10 55084094 55084144 chr14 9061995190620001 chr10 56467985 56468035 chr14 97892506 97892556 chr15 3129582331295873 chr15 34260484 34260534 chr10 63406105 63406155 chr15 5114975651149806 chr15 53516874 53516924 chr15 64580015 64580065 chr15 6599383065993880 chr15 75955973 75956023 chr15 95406942 95406992 chr16 4033640386 chr16 2875784 2875834 chr16 9541076 9541126 chr16 2109434721094397 chr16 46350455 46350505 chr16 59018412 59018462 chr16 6386730963867359 chr16 80483988 80484038 chr16 83331241 83331291 chr16 8668619986686249 chr16 89513481 89513531 chr17 1401598 1401648 chr17 19348551934905 chr17 2757948 2757998 chr10 76474112 76474162 chr17 57232785723328 chr17 6501641 6501691 chr10 78796541 78796591 chr10 7920740179207451 Table 15EH. Repeat Category THE1D chr17 48069632 48069682 chr1755703817 55703867 chr17 56679818 56679868 chr17 62017864 62017914 chr1762985967 62986017 chr17 63229393 63229443 chr17 65546067 65546117 chr1767146227 67146277 chr17 67161361 67161411 chr17 70550434 70550484 chr1777903258 77903308 chr17 78758576 78758626 chr10 91955066 91955116 chr1811359973 11360023 chr10 94729948 94729998 chr10 95007433 95007483 chr1823575893 23575943 chr18 28066112 28066162 chr18 32073297 32073347 chr1841444603 41444653 chr18 41447177 41447227 chr18 41941155 41941205 chr1850784563 50784613 chr18 51961457 51961507 chr10 97928901 97928951 chr1859429155 59429205 chr18 65651125 65651175 chr18 66268772 66268822 chr1874816367 74816417 chr19 2779151 2779201 chr19 11292980 11293030 chr1912929849 12929899 chr19 41609387 41609437 chr19 44106665 44106715 chr1945145464 45145514 chr19 47239676 47239726 chr19 47239756 47239806 chr1948646900 48646950 chr19 51377888 51377938 chr19 51772260 51772310 chr1954168230 54168280 chr19 54921140 54921190 chr19 59224969 59225019 chr1960967927 60967977 chr1 7645020 7645070 chr1 11432434 11432484 chr113350247 13350297 chr1 17412328 17412378 chr1 21188955 21189005 chr126865623 26865673 chr1 32549707 32549757 chr10 121037911 121037961 chr137339156 37339206 chr10 121367901 121367951 chr1 53041408 53041458 chr162183527 62183577 chr1 70221167 70221217 chr1 70297151 70297201 chr173442809 73442859 chr1 86871280 86871330 chr1 86871958 86872008 chr187460667 87460717 chr1 91046540 91046590 chr1 93345442 93345492 chr193889011 93889061 chr1 100918633 100918683 chr1 101756050 101756100 chr1102510060 102510110 chr1 150070877 150070927 chr10 128348785 128348835chr1 159100466 159100516 chr1 160467872 160467922 chr1 191144825191144875 chr1 192320899 192320949 chr1 200968211 200968261 chr1215143042 215143092 chr1 228601973 228602023 chr1 228972793 228972843chr1 231297636 231297686 chr1 231915888 231915938 chr10 7665614 7665664chr10 132725774 132725824 chr20 5648083 5648133 chr20 33850794 33850844chr20 33850627 33850677 chr20 36429491 36429541 chr20 38392612 38392662chr20 41089142 41089192 chr20 46246626 46246676 chr20 53360942 53360992chr20 59694976 59695026 chr21 14723378 14723428 chr21 30930399 30930449chr21 38165799 38165849 chr21 40998192 40998242 chr21 43456370 43456420chr21 46284419 46284469 chr22 16954326 16954376 chr11 1326497 1326547chr22 27884289 27884339 chr11 2416073 2416123 chr22 41829262 41829312chr22 46431520 46431570 chrX 2978061 2978111 chrX 4684361 4684411 chrX8471941 8471991 chr11 6538175 6538225 chrX 54134301 54134351 chr1011071454 11071504 chrX 70298556 70298606 chrX 74927522 74927572 chrX77724057 77724107 chr11 9094903 9094953 chrX 84113053 84113103 chrX86117641 86117691 chrX 88572783 88572833 chrX 94492126 94492176 chrX95760737 95760787 chrX 100223831 100223881 chrX 110650889 110650939 chrX117586594 117586644 chrX 119765572 119765622 chr11 10816251 10816301chr11 12007232 12007282 chrX 136405028 136405078 chrX 142191397142191447 chrX 145517100 145517150 chr11 12975399 12975449 chr1112975344 12975394 chrX 152357970 152358020 chrY 2721519 2721569 chrY3524266 3524316 chrY 3694734 3694784 chr11 14842298 14842348 chr25588728 5588778 chr2 11112249 11112299 chr2 20047873 20047923 chr220047781 20047831 chr2 25972860 25972910 chr2 35832226 35832276 chr244349441 44349491 chr2 45311857 45311907 chr2 46408570 46408620 chr250034204 50034254 chr2 53710875 53710925 chr2 54595758 54595808 chr256880138 56880188 chr11 24400944 24400994 chr2 76142161 76142211 chr286468772 86468822 chr11 29710195 29710245 chr2 102391866 102391916 chr2102391749 102391799 chr2 120789006 120789056 chr2 122178407 122178457chr2 131749860 131749910 chr2 136371215 136371265 chr2 142792967142793017 chr2 144000301 144000351 chr2 167367496 167367546 chr2186190981 186191031 chr2 196446537 196446587 chr2 198423202 198423252chr11 41461409 41461459 chr2 211339566 211339616 chr2 216530365216530415 chr2 220755499 220755549 chr2 221941094 221941144 chr2222196578 222196628 chr2 224563640 224563690 chr2 227697537 227697587chr2 233036508 233036558 chr2 236074484 236074534 chr2 238276865238276915 chr2 238943954 238944004 chr2 238943884 238943934 chr3 53480355348085 chr3 11434869 11434919 chr3 31105738 31105788 chr3 4175650241756552 chr3 41756351 41756401 chr3 51861954 51862004 chr3 5575369455753744 chr3 61655195 61655245 chr3 63207815 63207865 chr3 6504537965045429 chr11 58173467 58173517 chr3 85500278 85500328 chr3 101289390101289440 chr3 104787959 104788009 chr3 118806087 118806137 chr3141194320 141194370 chr3 145608199 145608249 chr3 165218910 165218960chr3 169357566 169357616 chr3 171846734 171846784 chr3 188030708188030758 chr11 63139942 63139992 chr3 194195897 194195947 chr3194797247 194797297 chr4 3466926 3466976 chr4 3467668 3467718 chr44968519 4968569 chr4 7670849 7670899 chr4 14377301 14377351 chr422863337 22863387 chr4 34130421 34130471 chr4 34680755 34680805 chr435233686 35233736 chr4 38119008 38119058 chr4 41284999 41285049 chr443335826 43335876 chr4 52879614 52879664 chr4 52879456 52879506 chr1013372080 13372130 chr4 68572670 68572720 chr4 72376738 72376788 chr473345511 73345561 chr4 82747687 82747737 chr4 85506141 85506191 chr489405601 89405651 chr4 89405262 89405312 chr4 94906032 94906082 chr4113182652 113182702 chr4 121162309 121162359 chr4 121753255 121753305chr4 131969982 131970032 chr4 134324249 134324299 chr4 164865357164865407 chr4 164987585 164987635 chr4 167497710 167497760 chr4170153632 170153682 chr4 191613838 191613888 chr5 2906653 2906703 chr53590738 3590788 chr5 20828932 20828982 chr5 21993397 21993447 chr523252956 23253006 chr5 23489899 23489949 chr5 23927213 23927263 chr529758633 29758683 chr11 69763113 69763163 chr5 32508931 32508981 chr1169887353 69887403 chr5 35560324 35560374 chr5 39031819 39031869 chr540491778 40491828 chr5 44884357 44884407 chr5 45862330 45862380 chr556981829 56981879 chr5 56981397 56981447 chr5 56995986 56996036 chr562320051 62320101 chr5 68557784 68557834 chr5 68591236 68591286 chr1170471508 70471558 chr11 70556198 70556248 chr5 75094719 75094769 chr575094792 75094842 chr5 80537325 80537375 chr5 84783628 84783678 chr586560281 86560331 chr5 90593429 90593479 chr5 100568126 100568176 chr5106422888 106422938 chr5 117619260 117619310 chr5 117736291 117736341chr5 141480312 141480362 chr5 155716639 155716689 chr5 156934807156934857 chr11 74384051 74384101 chr5 157443683 157443733 chr5157445895 157445945 chr5 174988631 174988681 chr11 76352926 76352976chr11 76481368 76481418 chr5 179802331 179802381 chr6 3730305 3730355chr6 7328002 7328052 chr6 9080274 9080324 chr6 15595691 15595741 chr615595571 15595621 chr6 21233228 21233278 chr6 24329230 24329280 chr1181265431 81265481 chr6 27073075 27073125 chr6 34403893 34403943 chr635774953 35775003 chr6 38350720 38350770 chr6 46641817 46641867 chr652797671 52797721 chr6 57681279 57681329 chr6 66632728 66632778 chr669530768 69530818 chr6 71333243 71333293 chr6 75504907 75504957 chr681903529 81903579 chr6 83001016 83001066 chr6 97198957 97199007 chr6120307337 120307387 chr6 123209767 123209817 chr6 126606182 126606232chr6 137805431 137805481 chr6 139003253 139003303 chr6 139149367139149417 chr6 139793550 139793600 chr10 15608417 15608467 chr1015608232 15608282 chr6 151317472 151317522 chr11 100196111 100196161chr6 153188489 153188539 chr6 153804560 153804610 chr6 160878887160878937 chr6 161091126 161091176 chr6 164269279 164269329 chr6164269165 164269215 chr6 165526450 165526500 chr11 103007823 103007873chr6 166207679 166207729 chr11 103245047 103245097 chr7 2653220 2653270chr7 3753284 3753334 chr7 4401802 4401852 chr7 4859467 4859517 chr75597813 5597863 chr7 12107515 12107565 chr7 18635316 18635366 chr722322101 22322151 chr7 32470528 32470578 chr7 32580145 32580195 chr737443951 37444001 chr7 39622435 39622485 chr7 44973021 44973071 chr756978683 56978733 chr7 57287551 57287601 chr7 63120931 63120981 chr764214264 64214314 chr11 115060752 115060802 chr7 71087236 71087286 chr771282581 71282631 chr7 83084432 83084482 chr7 83563346 83563396 chr799800870 99800920 chr7 99800634 99800684 chr7 101285405 101285455 chr7104801841 104801891 chr7 123724604 123724654 chr7 130423235 130423285chr7 132682841 132682891 chr7 143748226 143748276 chr7 143962506143962556 chr7 146503874 146503924 chr7 147450479 147450529 chr7152272636 152272686 chr8 1113338 1113388 chr8 1738797 1738847 chr82041578 2041628 chr8 3125027 3125077 chr8 5815959 5816009 chr8 1111830311118353 chr8 11874918 11874968 chr8 14540955 14541005 chr8 1471893014718980 chr8 17298645 17298695 chr8 17921747 17921797 chr8 1967690419676954 chr8 20676624 20676674 chr8 23924581 23924631 chr8 2992023029920280 chr8 31122643 31122693 chr8 41300480 41300530 chr8 4798005147980101 chr8 70844439 70844489 chr8 76491538 76491588 chr8 7662632576626375 chr8 76628152 76628202 chr8 77300318 77300368 chr8 8703122687031276 chr8 88780488 88780538 chr8 111346851 111346901 chr8 115680711115680761 chr8 115844280 115844330 chr8 125140793 125140843 chr8135633941 135633991 chr8 138029501 138029551 chr8 141044675 141044725chr8 141044439 141044489 chr9 4534565 4534615 chr9 16923052 16923102chr9 16973407 16973457 chr9 17359602 17359652 chr9 30606051 30606101chr9 40667587 40667637 chr9 74527285 74527335 chr10 21072345 21072395chr9 94162449 94162499 chr9 101625822 101625872 chr9 110675809 110675859chr9 115060157 115060207 chr9 115059518 115059568 chr9 119205835119205885 chr9 119401902 119401952 chr9 120243950 120244000 chr9124399947 124399997 chr10 21874435 21874485 chr12 8010771 8010821 chr1226129464 26129514 chr12 38883757 38883807 chr12 41355906 41355956 chr1243745316 43745366 chr12 43745509 43745559 chr12 46553856 46553906 chr1247863804 47863854 chr12 56050168 56050218 chr12 58647722 58647772 chr1259136119 59136169 chr12 67828091 67828141 chr12 68104726 68104776 chr1272705579 72705629 chr12 73238994 73239044 chr12 78898913 78898963 chr1281461078 81461128 chr12 83261370 83261420 chr12 89608008 89608058 chr1289632706 89632756 chr12 92519973 92520023 chr12 92528285 92528335 chr12108540193 108540243 chr12 114891204 114891254 chr12 122681491 122681541chr12 123507139 123507189 chr10 33773888 33773938 chr12 124447138124447188 chr12 124532238 124532288 chr12 128660138 128660188 chr1326562555 26562605 chr13 32034086 32034136 chr13 34821242 34821292 chr1339482195 39482245 chr13 39768990 39769040 chr10 42235300 42235350 chr1357984823 57984873 chr13 60820375 60820425 chr13 64604546 64604596 chr1368227740 68227790 chr13 70526253 70526303 chr13 78795969 78796019 chr1379518935 79518985 chr13 87557235 87557285 chr13 93357611 93357661 chr13101519354 101519404 chr13 103750266 103750316 chr13 105229716 105229766chr13 109589028 109589078 chr14 28192632 28192682 chr14 2841069128410741 chr14 29504502 29504552 chr14 40465885 40465935 chr14 4530387045303920 chr14 45673413 45673463 chr14 48863603 48863653 chr14 6224026962240319 chr14 65028294 65028344 chr14 65189705 65189755 chr14 7751550077515550 chr14 83969844 83969894 chr14 86225265 86225315 chr14 8767590087675950 chr14 89250952 89251002 chr14 90125343 90125393 chr14 9594706095947110 chr14 101651173 101651223 chr14 102907347 102907397 chr1520536796 20536846 chr15 23852540 23852590 chr15 35206036 35206086 chr1537287148 37287198 chr15 40505373 40505423 chr15 42425918 42425968 chr1544348022 44348072 chr15 50549867 50549917 chr15 87300995 87301045 chr1589746193 89746243 chr15 98153048 98153098 chr15 98477171 98477221 chr1598692502 98692552 chr16 737137 737187 chr16 4150930 4150980 chr166861161 6861211 chr16 10199562 10199612 chr16 10821743 10821793 chr1610821691 10821741 chr16 13721231 13721281 chr16 22636284 22636334 chr1624006986 24007036 chr16 54127369 54127419 chr16 57534152 57534202 chr1660071023 60071073 chr16 60338285 60338335 chr16 62308324 62308374 chr1665386492 65386542 chr16 66686535 66686585 chr16 74677251 74677301 chr1676617176 76617226 chr16 77472991 77473041 chr16 86414160 86414210 chr1686686199 86686249 chr16 89436254 89436304 chr16 89438836 89438886 chr173035453 3035503 chr17 13913677 13913727 Table 15EI. Repeat Category U1chr17 47501447 47501497 chr17 57218909 57218959 chr17 65954059 65954109chr18 3413958 3414008 chr19 11410623 11410673 chr19 44231592 44231642chr19 52143735 52143785 chr1 6988998 6989048 chr1 16221591 16221641 chr116603248 16603298 chr1 24344600 24344650 chr1 28521410 28521460 chr145237333 45237383 chr1 108864439 108864489 chr1 142425044 142425094 chr1143131391 143131441 chr1 143674498 143674548 chr1 143698675 143698725chr1 143820974 143821024 chr1 144063380 144063430 chr1 146129449146129499 chr1 221338206 221338256 chr20 49242053 49242103 chr2141910493 41910543 chr22 16498997 16499047 chr22 39554301 39554351 chrX2325388 2325438 chrX 117311925 117311975 chr2 97131960 97132010 chr2100815232 100815282 chr2 130277949 130277999 chr2 219396064 219396114chr2 233746072 233746122 chr3 72542783 72542833 chr3 123790004 123790054chr3 126486150 126486200 chr3 133320736 133320786 chr5 137527124137527174 chr5 170918705 170918755 chr6 4021635 4021685 chr6 4783836247838412 chr6 89419682 89419732 chr6 108352806 108352856 chr6 108352726108352776 chr7 5269210 5269260 chr7 29694750 29694800 chr7 6531117265311222 chr7 137276851 137276901 chr7 151684647 151684697 chr11122468037 122468087 chr9 131244434 131244484 chr9 135375222 135375272chr12 87477986 87478036 chr12 129653009 129653059 chr14 100815275100815325 chr15 80182352 80182402 chr10 69817367 69817417 chr16 1162471911624769 chr16 67200540 67200590 chr17 1726256 1726306 chr17 77152377715287

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1. A method of assessing one or more statuses of a subject, the methodcomprising: determining the methylation state of one or more statusbiomarkers in the subject, comparing one or more of the determinedmethylation states to one or more reference methylation states, whereina difference, lack of a difference, or both in one or more of thedetermined methylation states and one or more of the referencemethylation states indicates one or more statuses of the subject.
 2. Themethod of claim 1, wherein the status biomarkers comprise nucleic acidsequences in the genome of the species to which the subject belongs,wherein the nucleic acid sequences are in proximity to CpG islands orislets, wherein the CpG islands or islets comprise nucleic acid regionsgreater than 100 nucleotides in length that contain a minimum of 5 CpGresidues and have a ratio of CG content to GC content greater than 0.3.3-8. (canceled)
 9. The method of claim 2, wherein one or more of thestatus biomarkers comprises a probe binding site, wherein the probebinding site of the one or more of the status biomarkers is specific fora probe.
 10. The method of claim 9, wherein one or more of the probesare specific for a repetitive DNA sequence locus, wherein the repetitiveDNA sequence locus comprises one or more repetitive DNA sequences,wherein independently for each of the one or more of the probes one ormore of the repetitive DNA sequences belongs to a family of repetitiveDNA sequences listed in Table
 1. 11. The method of claim 10, whereineach probe is specific for a repetitive DNA sequence locus, whereinindependently for each probe one or more of the repetitive DNA sequencesbelongs to a family of repetitive DNA sequences listed in Table 1.12-21. (canceled)
 22. The method of claim 1, wherein the methylationstate of more than 100 biomarkers is determined. 23-26. (canceled) 27.The method of claim 1, wherein a plurality of the biomarkersindependently belong to one or more status biomarker families, whereineach biomarker in each status biomarker family comprises one or morerepetitive DNA sequences that belong to a single family of repetitiveDNA sequences listed in Table
 1. 28-41. (canceled)
 42. The method ofclaim 1, wherein the status biomarkers comprise a set of statusbiomarkers, wherein the members of the set of status biomarkers arestatus biomarkers that indicate the status of one or more specificstatuses.
 43. The method of claim 42, wherein the one or more specificstatuses comprise wellness, level of health, risk to wellness, risk tolevel of health, status of the genome, genomic instability, aging, riskof aging, cancer, risk of cancer, head and neck cancer, risk of head andneck cancer, breast cancer, risk of breast cancer, lung cancer, risk oflung cancer, prostate cancer, risk of prostate cancer, colon cancer,risk of colon cancer, esophageal cancer, risk of esophageal cancer,ovarian cancer, risk of ovarian cancer, liver cancer, risk of livercancer, pancreatic cancer, risk of pancreatic cancer, skin cancer, riskof skin cancer, melanoma, risk of melanoma, lymphoma, risk of lymphoma,leukemia, risk of leukemia, cervical cancer, risk of cervical cancer,cervical dysplasia, risk of cervical dysplasia, cervical intraepithelialneoplasia, risk of cervical intraepithelial neoplasia, tumor burden,stress response, diabetes, risk of diabetes, heart disease, risk ofheart disease, and response to treatment.
 44. (canceled)
 45. The methodof claim 1, wherein the one or more specific statuses comprise a lack ofwellness, low level of health, risk to wellness, risk to level ofhealth, poor status of the genome, genomic instability, aging, risk ofaging, cancer, risk of cancer, head and neck cancer, risk of head andneck cancer, breast cancer, risk of breast cancer, lung cancer, risk oflung cancer, prostate cancer, risk of prostate cancer, colon cancer,risk of colon cancer, esophageal cancer, risk of esophageal cancer,ovarian cancer, risk of ovarian cancer, liver cancer, risk of livercancer, pancreatic cancer, risk of pancreatic cancer, skin cancer, riskof skin cancer, melanoma, risk of melanoma, lymphoma, risk of lymphoma,leukemia, risk of leukemia, cervical cancer, risk of cervical cancer,cervical dysplasia, risk of cervical dysplasia, cervical intraepithelialneoplasia, risk of cervical intraepithelial neoplasia, tumor burden,stress response, diabetes, risk of diabetes, heart disease, and risk ofheart disease.
 46. The method of claim 1, wherein the methylation stateis determined by treating a DNA sample of the subject to differentiatemethylated and unmethylated nucleotides, detecting the level ofmethylated forms of the one or more status biomarkers in the treatedDNA, detecting the level of unmethylated forms of the one or more statusbiomarkers in the treated DNA, or both, wherein the level of methylatedforms of the status biomarkers, the level of unmethylated forms of thestatus biomarkers, or both indicates the methylation state of the statusbiomarkers.
 47. The method of claim 46, wherein treating the DNA sampleis accomplished by incubating the DNA sample with one or morerestriction endonucleases and amplifying the incubated DNA, wherein therestriction endonucleases are methylation-sensitive restrictionendonucleases, wherein the level of the status biomarkers in theamplified DNA is lower when the status biomarkers have reducedmethylation and the level of the status biomarkers in the amplified DNAis higher when the status biomarkers have increased methylation, whereinthe level of the status biomarkers comprise the level of methylatedforms of the one or more status biomarkers in the treated DNA, the levelof unmethylated forms of the one or more status biomarkers in thetreated DNA, or both. 48-53. (canceled)
 54. The method of claim 46,wherein treating the DNA sample is accomplished by processing the DNAsample with sodium bisulfite.
 55. The method of claim 46, whereintreating the DNA sample is accomplished by fragmenting the DNA andseparating methylated DNA from unmethylated DNA.
 56. (canceled)
 57. Themethod of claim 55, wherein methylated DNA is separated fromunmethylated DNA by binding methylated DNA with a specific bindingmolecule specific for methyl groups and separating the bound form theunbound DNA.
 58. (canceled)
 59. The method of claim 46, wherein treatingthe DNA sample is accomplished by capturing status biomarker DNAfragments and sequencing the captured status biomarker DNA fragments,wherein the sequencing distinguishes cytosine from methylcytosine,wherein the level of methylcytosine indicates level of methylated formsof the status biomarkers. 60-68. (canceled)
 69. The method of claim 59further comprising, after capturing status biomarker DNA fragments andprior to sequencing the captured status biomarker DNA fragments,releasing the captured status biomarker DNA fragments and recapturingthe released status biomarker DNA fragments. 70-76. (canceled)
 77. Themethod of claim 46, wherein detecting the level of the status biomarkersis accomplished via an array of probes specific for the statusbiomarkers.
 78. (canceled)
 79. The method of claim 77, wherein detectingthe level of the status biomarkers is accomplished via amplifying theprocessed DNA and determining the ratio of cytosine to thymidine in theamplified DNA and converting the ratio to the level of methylated formsof the status biomarkers.
 80. (canceled)
 81. The method of claim 46,wherein detecting the level of the status biomarkers is accomplished viaPCR amplification of the status biomarkers using primers specific forthe status biomarkers. 82-83. (canceled)
 84. The method of claim 46,wherein the level of the status biomarkers are grouped into a pluralityof status biomarker families, wherein the level of the status biomarkersin one or more of the families is analyzed, wherein the analyzed levelof the status biomarkers in the one or more of the families indicatesthe methylation state of the status biomarkers in the family. 85-87.(canceled)
 88. The method of claim 1, wherein the level of one or moreof the status biomarkers is normalized to one or more of the referencemethylation states.
 89. The method of claim 27, wherein the level of oneor more of the status biomarker families is normalized to one or more ofthe reference methylation states.
 90. The method of claim 84, whereinthe status biomarkers are grouped according to one or more repetitiveDNA sequences that the status biomarkers comprise, wherein eachbiomarker in each status biomarker family comprises one or morerepetitive DNA sequences that belong to a single family of repetitiveDNA sequences listed in Table
 1. 91-92. (canceled)
 93. The method ofclaim 1, wherein one or more of the one or more reference methylationstates is the methylation state of the same subject at a different time,the methylation state of the same subject at an earlier time, themethylation state of the same subject at a later time, or themethylation state of one or more normal cells, tissues, organs, or acombination of the same subject.
 94. The method of claim 1, wherein oneor more of the one or more reference methylation states is themethylation state from non-tumor adjacent tissue.
 95. (canceled)
 96. Themethod of claim 1 further comprising determining the genetic state ofone or more status biomarkers, comparing one or more of the determinedgenetic states to one or more reference genetic states, wherein adifference, lack of a difference, or both in one or more of thedetermined genetic states and one or more of the reference geneticstates indicates one or more statuses of the subject.
 97. The method ofclaim 46, wherein the source of one or more of the DNA samples is one ormore tissues of the subject, organs of the subject, or both. 98-100.(canceled)
 101. The method of claim 1, wherein the subject is assessedfor the status of wellness, level of health, risk to wellness, risk tolevel of health, or a combination. 102-117. (canceled)
 118. A set of oneor more status biomarkers, wherein the status biomarkers comprisenucleic acid sequences in a genome, wherein the nucleic acid sequencesare in proximity to CpG islands or islets, wherein the CpG islands orislets comprise nucleic acid regions greater than 100 nucleotides inlength that contain a minimum of 5 CpG residues and have a ratio of CGcontent to GC content greater than 0.3.
 119. The method of claim 118,wherein the CpG islands or islets comprise nucleic acid regions greaterthan 200 nucleotides in length. 120-125. (canceled)
 126. The set ofclaim 118, wherein one or more of the status biomarkers comprises aprobe binding site, wherein the probe binding site of the one or more ofthe status biomarkers is specific for a probe, wherein one or more ofthe probes are specific for a repetitive DNA sequence locus, wherein therepetitive DNA sequence locus comprises one or more repetitive DNAsequences, wherein independently for each of the one or more of theprobes one or more of the repetitive DNA sequences belongs to a familyof repetitive DNA sequences listed in Table
 1. 127. The set of claim126, wherein each probe is specific for a repetitive DNA sequence locus,wherein independently for each probe one or more of the repetitive DNAsequences belongs to a family of repetitive DNA sequences listed inTable
 1. 128-162. (canceled)
 163. A method of identifying statusbiomarkers associated with a status of a subject, the method comprising:determining the methylation state of one or more status biomarkers inone or more DNA samples, wherein the DNA samples are from sources thatare relevant to one or more specific statuses, comparing one or more ofthe determined methylation states to one or more reference methylationstates, wherein a difference in one or more of the determinedmethylation states and one or more of the reference methylation statesindicates that the status biomarkers for which the difference in themethylation states is found is a status biomarker associated with one ormore of the specific statuses.
 164. The method of claim 163, wherein thestatus biomarkers comprise nucleic acid sequences in the genome of thespecies to which the subject belongs, wherein the nucleic acid sequencesare in proximity to CpG islands or islets, wherein the CpG islands orislets comprise nucleic acid regions greater than 100 nucleotides inlength that contain a minimum of 5 CpG residues and have a ratio of CGcontent to GC content greater than 0.3. 165-171. (canceled)
 172. Themethod of claim 164, wherein one or more of the status biomarkerscomprises a probe binding site, wherein the probe binding site of theone or more of the status biomarkers is specific for a probe, whereinone or more of the probes are specific for a repetitive DNA sequencelocus, wherein the repetitive DNA sequence locus comprises one or morerepetitive DNA sequences, wherein independently for each of the one ormore of the probes one or more of the repetitive DNA sequences belongsto a family of repetitive DNA sequences listed in Table
 1. 173. Themethod of claim 172, wherein each probe is specific for a repetitive DNAsequence locus, wherein independently for each probe one or more of therepetitive DNA sequences belongs to a family of repetitive DNA sequenceslisted in Table
 1. 174-262. (canceled)
 263. A method of producing statusbiomarker capture probes, the method comprising selecting a subset ofrepetitive DNA sequence loci from a set of repetitive DNA sequence loci,wherein the repetitive DNA sequence loci in the set of repetitive DNAsequence loci belong to a single one of the families of repetitive DNAsequence listed in Table 1, wherein the subset of repetitive DNAsequence loci are selected by identifying those repetitive DNA sequenceloci that comprise a repetitive DNA sequence belonging to one of thefamilies of repetitive DNA sequences listed in Table 17, generating aset of status biomarker capture probe sequences, wherein each statusbiomarker capture probe sequence in the set has a length of 50 bases ormore, wherein each status biomarker capture probe represented in the setof status biomarker capture probe sequences can hybridize to at least 5%of the repetitive DNA sequence loci in the selected subset of repetitiveDNA sequence loci, synthesizing one or more status biomarker captureprobes, wherein each status biomarker capture probe has the sequence ofone of the status biomarker capture probe sequences.
 264. The method ofclaim 263, wherein the repetitive DNA sequence loci in the set ofrepetitive DNA sequence loci belong to a single one of the families ofrepetitive DNA sequence LTR54B, MER11B, MER34B, LTR56, THE1B, HERV9,LTR14C, HERVFH21, LTR6B, LTR46, MLT1D, MER67D, HERVK11, LTR10B, HERVK22,MER6, MER66C, MLT1G1, MER4D, and MLTD2.
 265. The method of claim 263further comprising selecting one or more additional subsets ofrepetitive DNA sequence loci each from a different additional set ofrepetitive DNA sequence loci, generating one or more additional sets ofstatus biomarker capture probe sequences each based on one of the one ormore additional subsets, and synthesizing one or more additional statusbiomarker capture probes, wherein each additional status biomarkercapture probe has the sequence of one of the additional status biomarkercapture probe sequences, wherein the repetitive DNA sequence loci ineach additional set of repetitive DNA sequence loci independently belongto a different single one of the families of repetitive DNA sequencelisted in Table 1, wherein the repetitive DNA sequence loci in the setof repetitive DNA sequence loci and in each additional set of repetitiveDNA sequence loci belong to different families of repetitive DNAsequence. 266-274. (canceled)